MicroScope - Tutorial   »   Experimental Data   »   Evolution Projects   »   First steps
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How to begin ?

Once your evolution project selected (1 and 2), just click one of the radio buttons to switch between the different exploration modes (3):

(PNG)
  • Comparative analysis => Click here for more details.
  • Parallelism analysis => Click here for more details.
  • Graphical analysis => Click here for more details.

What is the meaning of the score computed by SNiPer for each variation ?

For each reported mutation, a score, which is meant to indicate the confidence one can have in the prediction, is computed:

  • SNP_score=
    lctc.png (PNG)
    • Local-coverage : Number of reads containing the new base with a high quality.
    • Total-coverage : Total number of reads containing the new base.
  • indel_score=
    lctc.png (PNG)
    • Local-coverage : Number of reads containing the indel.
    • Total-coverage : Total number of reads mapping the mutated position.