MicroScope Platform Overview
- Overview of the annotation editor
- Annotation Rules
- BLAST results
- Compositional features
- E. coli K12
- B. subtilis
- MaGe/Curated annotations
- Syntonome / Syntonome RefSeq
- Similarities SwissProt / TrEMBL
- Predicted MetaCyc Pathways
MicroScope - Tutorial » MaGe » Gene Annotation Editor » TMhmm
What is TMhmm ?
TMHMM is a program for the prediction of transmembrane helices based on a hidden Markov model. The program reads a fasta-formatted protein sequence and predicts locations of transmembrane, intracellular and extracellular regions.
How to read TMhmm results
The table of results indicates the begin and end positions of detected alpha-helices for the protein sequence. It also gives the location (inside/outside) of the fragments in between the helices.
Tips: As protein can be called « membranar » if it contains more than 3 alpha-helices.