Label Type Frame Begin End Mutation Gene Product Score OG_id OG_function COGclassID COGprocess COGClassDescription ACIAD0001 CDS +3 201 1598 no dnaA Chromosomal replication initiator protein dnaA 904 3NIMU it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids L INFORMATION STORAGE AND PROCESSING Replication, recombination and repair ACIAD0002 CDS +1 1834 2982 no dnaN DNA polymerase III, beta chain 720 3NJI0 Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria L INFORMATION STORAGE AND PROCESSING Replication, recombination and repair ACIAD0003 CDS +1 2998 4074 no recF DNA replication, recombinaison and repair protein 707 3NKN9 it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP L INFORMATION STORAGE AND PROCESSING Replication, recombination and repair ACIAD0004 CDS +2 4127 6595 no gyrB DNA gyrase, subunit B (type II topoisomerase) 1608 3NJZQ A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner L INFORMATION STORAGE AND PROCESSING Replication, recombination and repair ACIAD0005 CDS -2 6712 6948 no conserved hypothetical protein (DUF2171 domain-containing protein) 160 3NTHP Uncharacterized protein conserved in bacteria (DUF2171) S POORLY CHARACTERIZED Function unknown ACIAD0007 CDS -2 7336 9270 no putative transport protein (ABC superfamily, atp_bind) 1224 3NINK COG0488 ATPase components of ABC transporters with duplicated ATPase domains S POORLY CHARACTERIZED Function unknown ACIAD0008 CDS +3 9651 10661 no putative RND type efflux pump involved in aminoglycoside resistance (AdeT) 667 3NINA TRAP-type C4-dicarboxylate transport system periplasmic component G METABOLISM Carbohydrate transport and metabolism ACIAD0009 CDS +2 10910 11920 no adeT RND type efflux pump involved in aminoglycoside resistance 670 3NK45 TRAP-type C4-dicarboxylate transport system periplasmic component G METABOLISM Carbohydrate transport and metabolism ACIAD0010 CDS +3 12039 12374 no putative chaperone involved in Fe-S cluster assembly and activation (HesB-like) 223 3NNK9 Iron-sulfur cluster insertion protein ErpA C METABOLISM Energy production and conversion ACIAD0011 CDS -2 12436 13566 no anmK Anhydro-N-acetylmuramic acid kinase (AnhMurNAc kinase) 768 3NJF2 Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling F METABOLISM Nucleotide transport and metabolism ACIAD0013 CDS +2 13646 14860 no tyrS tyrosyl-tRNA synthetase 796 3NK51 Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr) J INFORMATION STORAGE AND PROCESSING Translation, ribosomal structure and biogenesis ACIAD0014 CDS +2 15431 15685 no conserved hypothetical protein 178 3NPNZ S POORLY CHARACTERIZED Function unknown ACIAD0015 CDS +3 15927 17882 no putative 5'-nucleotidase NucA precursor 1258 3NJWC 5'-nucleotidase, C-terminal domain F METABOLISM Nucleotide transport and metabolism ACIAD0017 CDS +3 23916 24530 no putative glutathione S-transferase 423 3NMXE Glutathione S-transferase, C-terminal domain O CELLULAR PROCESSES AND SIGNALING Posttranslational modification, protein turnover, chaperones ACIAD0018 CDS +2 24584 24895 no conserved hypothetical protein 197 3NNYC Ankyrin repeats (many copies) S POORLY CHARACTERIZED Function unknown ACIAD0019 CDS -3 25116 25658 no putative NAD(P)H-dependent FMN reductase 361 3NIJ3 NADPH-dependent FMN reductase S POORLY CHARACTERIZED Function unknown ACIAD0020 CDS -1 25757 26239 no fkpB FKBP-type peptidyl-prolyl cis-trans isomerase (rotamase) 323 3NJ55 Peptidyl-prolyl cis-trans G METABOLISM Carbohydrate transport and metabolism ACIAD0021 CDS -3 26232 26771 no lspA prolipoprotein signal peptidase (Signal peptidase II.) 368 3NJUG This protein specifically catalyzes the removal of signal peptides from prolipoproteins M CELLULAR PROCESSES AND SIGNALING Cell wall/membrane/envelope biogenesis ACIAD0021 CDS -3 26232 26771 no lspA prolipoprotein signal peptidase (Signal peptidase II.) 368 3NJUG This protein specifically catalyzes the removal of signal peptides from prolipoproteins U CELLULAR PROCESSES AND SIGNALING Intracellular trafficking, secretion, and vesicular transport ACIAD0022 CDS -2 26764 29601 no ileS isoleucyl-tRNA synthetase 1934 3NIHR amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile) J INFORMATION STORAGE AND PROCESSING Translation, ribosomal structure and biogenesis ACIAD0023 CDS -1 29666 30667 no ribF bifunctional protein [Includes: riboflavin kinase (Flavokinase); FMN adenylyltransferase (FAD pyrophosphorylase) (FAD synthetase)] 676 3NJWF Belongs to the ribF family H METABOLISM Coenzyme transport and metabolism ACIAD0024 CDS +3 30876 32000 no putative malic acid transport protein 742 3NJUA Voltage-dependent anion channel P METABOLISM Inorganic ion transport and metabolism ACIAD0025 CDS +2 32045 32845 no rutD Putative carbamate hydrolase RutD (Pyrimidine utilization protein D) 542 3NKAK May increase the rate of spontaneous hydrolysis of aminoacrylate to malonic semialdehyde. Required to remove a toxic intermediate produce in the pyrimidine nitrogen degradation S POORLY CHARACTERIZED Function unknown ACIAD0026 CDS -1 32918 33535 no rutR DNA-binding transcriptional regulator of the alternative pyrimidine degradation pathway (Rut operon repressor) 400 3NIZ8 YcdC-like protein, C-terminal region K INFORMATION STORAGE AND PROCESSING Transcription ACIAD0027 CDS +1 33988 35097 no rutA Putative Pyrimidine monooxygenase rutA (Pyrimidine utilization protein A) 740 3NJKB Catalyzes the pyrimidine ring opening between N-3 and C- 4 by an unusual flavin hydroperoxide-catalyzed mechanism to yield ureidoacrylate peracid. It cleaves pyrmidine rings directly by adding oxygen atoms, making a toxic ureidoacrylate peracid product which can be spontaneously reduced to ureidoacrylate C METABOLISM Energy production and conversion ACIAD0028 CDS +3 35094 35831 no rutB Putative ureidoacrylate amidohydrolase RutB (Pyrimidine utilization protein B) 493 3NJDP In vivo, quickly hydrolyzes the ureidoacrylate peracid to avoid toxicity, but can also hydrolyzes ureidoacrylate that is formed spontaneously from ureidoacrylate peracid. One of the products of hydrolysis, carbamate, hydrolyzes spontaneously, thereby releasing one of the pyrimidine rings nitrogen atoms as ammonia and one of its carbons as CO2 Q METABOLISM Secondary metabolites biosynthesis, transport and catabolism ACIAD0029 CDS +3 35844 36224 no rutC putative 3-aminoacrylate deaminase RutC (Pyrimidine utilization protein C) 256 3NNMM May reduce aminoacrylate peracid to aminoacrylate. Required to remove a toxic intermediate produce by the pyrimidine nitrogen degradation J INFORMATION STORAGE AND PROCESSING Translation, ribosomal structure and biogenesis ACIAD0030 CDS +3 36303 36869 no rutF putative FMN reductase (NADH) RutF (Pyrimidine utilization protein F) 376 3NNA1 Catalyzes the reduction of FMN to FMNH2 which is used to reduce pyrimidine by RutA via the Rut pathway C METABOLISM Energy production and conversion ACIAD0031 CDS +2 36899 38263 no rutG Putative pyrimidine permease rutG (Pyrimidine utilization protein G) 864 3NJBQ Permease family F METABOLISM Nucleotide transport and metabolism ACIAD0032 CDS +2 38279 39151 no putative hydroxyacid dehydrogenase/reductase 568 3NJ1Y NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase I METABOLISM Lipid transport and metabolism ACIAD0034 CDS -1 39182 39991 no ssuB alkanesulfonate transport protein (ABC superfamily, atp_bind) 520 3NK1K Part of the ABC transporter complex SsuABC involved in aliphatic sulfonates import. Responsible for energy coupling to the transport system P METABOLISM Inorganic ion transport and metabolism ACIAD0035 CDS -1 39995 40795 no ssuC alkanesulfonate transport protein (ABC superfamily, membrane) 502 3NIPE Binding-protein-dependent transport system inner membrane component P METABOLISM Inorganic ion transport and metabolism ACIAD0036 CDS -2 40792 41982 no ssuD FMNH(2)-dependent alkanesulfonate monooxygenase 791 3NITN Catalyzes the desulfonation of aliphatic sulfonates C METABOLISM Energy production and conversion ACIAD0037 CDS -1 42005 43012 no ssuA alkanesulfonate transport protein (ABC superfamily, peri_bind) 655 3NTAG Substrate binding domain of ABC-type glycine betaine transport system P METABOLISM Inorganic ion transport and metabolism ACIAD0038 CDS -2 43039 44061 no ssuA alkanesulfonate transport protein (ABC superfamily, peri_bind) 662 3NIW9 ABC transporter substrate-binding protein P METABOLISM Inorganic ion transport and metabolism ACIAD0039 CDS -2 44434 45789 no argA N-alpha-acetylglutamate synthase (amino-acid acetyltransferase) 885 3NIZC Belongs to the acetyltransferase family. ArgA subfamily E METABOLISM Amino acid transport and metabolism ACIAD0040 CDS -2 45901 46203 no conserved hypothetical protein; putative signal peptide 207 3NQ21 Nickel/cobalt transporter regulator S POORLY CHARACTERIZED Function unknown ACIAD0041 CDS -1 46379 46786 no conserved hypothetical protein; putative signal peptide 275 3NNTW Nickel/cobalt transporter regulator S POORLY CHARACTERIZED Function unknown ACIAD0042 CDS -2 47056 47802 no putative oxoacyl-(acyl carrier protein) reductase 488 3NJ4C KR domain I METABOLISM Lipid transport and metabolism ACIAD0042 CDS -2 47056 47802 no putative oxoacyl-(acyl carrier protein) reductase 488 3NJ4C KR domain Q METABOLISM Secondary metabolites biosynthesis, transport and catabolism ACIAD0043 CDS -2 47833 48540 no putative phosphoglycolate phosphatase 2 (PGP 2) 468 3NJ75 Phosphoglycolate phosphatase S POORLY CHARACTERIZED Function unknown ACIAD0044 CDS -3 48537 49253 no ubiG 3-demethylubiquinone-9 3-methyltransferase and 2-octaprenyl-6-hydroxy phenol methylase 488 3NKGB O-methyltransferase that catalyzes the 2 O-methylation steps in the ubiquinone biosynthetic pathway H METABOLISM Coenzyme transport and metabolism ACIAD0045 CDS +1 49432 50052 no dsbA thiol:disulfide interchange protein, periplasmic, alkali-inducible 415 3NJ0Z Thiol disulfide interchange protein O CELLULAR PROCESSES AND SIGNALING Posttranslational modification, protein turnover, chaperones ACIAD0046 CDS -2 50137 50811 no putative transcriptional regulator 431 3NJ4A Bacterial regulatory proteins, tetR family K INFORMATION STORAGE AND PROCESSING Transcription ACIAD0047 CDS -2 50905 51540 no conserved hypothetical protein; putative transcriptional regulator (TetR family) 407 3NKKM Bacterial regulatory proteins, tetR family K INFORMATION STORAGE AND PROCESSING Transcription ACIAD0048 CDS +3 51732 52754 no putative oxidoreductase 672 3NK4F Oxidoreductase NAD-binding domain C METABOLISM Energy production and conversion ACIAD0049 CDS +1 52789 53940 no putative fatty acid desaturase 792 3NIQ6 Fatty acid desaturase I METABOLISM Lipid transport and metabolism ACIAD0050 CDS +2 54008 54763 no rph ribonuclease PH (RNase PH), tRNA nucleotidyltransferase 485 3NJQV Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates J INFORMATION STORAGE AND PROCESSING Translation, ribosomal structure and biogenesis ACIAD0051 CDS +3 54987 55442 no PAAR motif-containing protein 294 3NNSI PAAR motif S POORLY CHARACTERIZED Function unknown ACIAD0052 CDS +1 55435 55983 no PAAR motif-containing protein 375 3NP0B PAAR motif S POORLY CHARACTERIZED Function unknown ACIAD0053 CDS +2 55985 56617 no hypothetical protein; putative zinc protease 418 3NPYK S POORLY CHARACTERIZED Function unknown ACIAD0054 CDS +2 56618 57070 no hypothetical protein; putative fragment of ribosomal protein S3 299 3NRV5 S POORLY CHARACTERIZED Function unknown ACIAD0056 CDS +3 57531 57689 no hypothetical protein 110 3NSA3 S POORLY CHARACTERIZED Function unknown ACIAD0057 fCDS +2 57779 58168 pseudo fragment of transposase (part 1) 178 3NKHK Transposase DDE domain L INFORMATION STORAGE AND PROCESSING Replication, recombination and repair ACIAD0058 fCDS +3 58242 58427 pseudo fragment of transposase (part 2) 90.9 3NKHK Transposase DDE domain L INFORMATION STORAGE AND PROCESSING Replication, recombination and repair ACIAD0059 fCDS +2 58409 58615 pseudo fragment of transposase (part 3) 93.2 3NKHK Transposase DDE domain L INFORMATION STORAGE AND PROCESSING Replication, recombination and repair ACIAD0061 CDS +3 59058 59261 no conserved hypothetical protein; putative signal peptide 125 3NQI4 S POORLY CHARACTERIZED Function unknown ACIAD0062 CDS -1 59258 60127 no nadC nicotinate-nucleotide pyrophosphorylase (quinolinate phosphoribosyltransferase) 550 3NJD6 Belongs to the NadC ModD family H METABOLISM Coenzyme transport and metabolism ACIAD0063 CDS +2 60290 60880 no ampD N-acetyl-anhydromuramyl-L-alanine amidase (Regulates ampC) 413 3NIXH Ami_2 V CELLULAR PROCESSES AND SIGNALING Defense mechanisms ACIAD0064 CDS +3 60933 62480 no putative virulence factor MviN family (multidrug/oligosaccharidyl-lipid/polysaccharide exporter superfamily) 996 3NITU Involved in peptidoglycan biosynthesis. Transports lipid-linked peptidoglycan precursors from the inner to the outer leaflet of the cytoplasmic membrane S POORLY CHARACTERIZED Function unknown ACIAD0065 CDS -1 62660 63358 no fklB FKBP-type 22KD peptidyl-prolyl cis-trans isomerase (rotamase) 437 3NJ27 peptidyl-prolyl cis-trans isomerase M CELLULAR PROCESSES AND SIGNALING Cell wall/membrane/envelope biogenesis ACIAD0066 CDS -1 63404 64111 no fkpA FKBP-type peptidyl-prolyl cis-trans isomerase (rotamase) 456 3NKXN Domain amino terminal to FKBP-type peptidyl-prolyl isomerase O CELLULAR PROCESSES AND SIGNALING Posttranslational modification, protein turnover, chaperones ACIAD0068 CDS -3 64281 66491 no ptk tyrosine-protein kinase, autophosphorylates 1246 3NJIK G-rich domain on putative tyrosine kinase D CELLULAR PROCESSES AND SIGNALING Cell cycle control, cell division, chromosome partitioning ACIAD0069 CDS -1 66506 66937 no ptp low molecular weight protein-tyrosine-phosphatase 302 3NNB0 Belongs to the low molecular weight phosphotyrosine protein phosphatase family T CELLULAR PROCESSES AND SIGNALING Signal transduction mechanisms ACIAD0070 CDS -2 66934 68037 no wza polysaccharide export protein 722 3NJF4 Polysaccharide biosynthesis/export protein M CELLULAR PROCESSES AND SIGNALING Cell wall/membrane/envelope biogenesis ACIAD0072 CDS +2 68507 69670 no ugd UDP-glucose 6-dehydrogenase 746 3NJSX Belongs to the UDP-glucose GDP-mannose dehydrogenase family M CELLULAR PROCESSES AND SIGNALING Cell wall/membrane/envelope biogenesis ACIAD0073 CDS +2 69689 70573 no putative glycosyl transferase family 2 582 3NNC3 Evidence 3 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology S POORLY CHARACTERIZED Function unknown ACIAD0074 CDS +3 70563 71492 no putative glycosyl transferase family 2 632 1SA3F glycosyl transferase family 2 M CELLULAR PROCESSES AND SIGNALING Cell wall/membrane/envelope biogenesis ACIAD0075 CDS +2 71489 72739 no putative polysaccharide transport protein 761 1S2YR Polysaccharide biosynthesis protein S POORLY CHARACTERIZED Function unknown ACIAD0076 CDS +1 72769 73839 no rmlB dTDP-D-glucose-4,6-dehydratase 732 3NIR1 RmlD substrate binding domain M CELLULAR PROCESSES AND SIGNALING Cell wall/membrane/envelope biogenesis ACIAD0078 CDS +1 73858 74766 no rmlD dTDP-4-dehydrorhamnose reductase (dTDP-4-keto-L- rhamnose reductase) (dTDP-6-deoxy-L-mannose dehydrogenase) (dTDP-L- rhamnose synthetase) 602 3NM08 Catalyzes the reduction of dTDP-6-deoxy-L-lyxo-4- hexulose to yield dTDP-L-rhamnose M CELLULAR PROCESSES AND SIGNALING Cell wall/membrane/envelope biogenesis ACIAD0079 CDS +1 74767 75666 no rmlA dTDP-glucose pyrophosphorylase (glucose-1-phosphate thymidylyltransferase) 596 3NJY8 Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis M CELLULAR PROCESSES AND SIGNALING Cell wall/membrane/envelope biogenesis ACIAD0080 CDS +2 75737 76300 no rmlC dTDP-4-keto-6-deoxy-D-glucose-3,5-epimerase 392 3NJVJ Catalyzes the epimerization of the C3' and C5'positions of dTDP-6-deoxy-D-xylo-4-hexulose, forming dTDP-6-deoxy-L-lyxo-4- hexulose M CELLULAR PROCESSES AND SIGNALING Cell wall/membrane/envelope biogenesis ACIAD0081 CDS +3 76353 77393 no putative glycosyl transferase family 1 691 1STQD Glycosyl transferases group 1 M CELLULAR PROCESSES AND SIGNALING Cell wall/membrane/envelope biogenesis ACIAD0082 CDS +1 77383 78330 no putative glycosyl transferase family 2 (rhamnosyl transferase) 629 3NQM1 Glycosyltransferase like family 2 M CELLULAR PROCESSES AND SIGNALING Cell wall/membrane/envelope biogenesis ACIAD0083 CDS +2 78350 79315 no conserved hypothetical protein; putative polysaccharide polymerase 571 1S3M9 EpsG family S POORLY CHARACTERIZED Function unknown ACIAD0084 CDS +3 79335 80354 no putative glycosyl transferase family 1 (mannosyl transferase) 696 3NPSW Glycosyl transferases group 1 M CELLULAR PROCESSES AND SIGNALING Cell wall/membrane/envelope biogenesis ACIAD0085 CDS +3 80367 81164 no putative glycosyl transferase family 2 544 3NMZE Glycosyl transferase family 2 S POORLY CHARACTERIZED Function unknown ACIAD0086 CDS -3 81192 82610 no epsM bifunctional protein [Includes: Mannose-6-phosphate isomerase (Phosphomannose isomerase) (Pmi) (Phosphohexomutase); Mannose-1-phosphate guanylyl transferase (Gdp) (GDP-mannose pyrophosphorylase) (Gmp)] 934 3NMRW Belongs to the mannose-6-phosphate isomerase type 2 family M CELLULAR PROCESSES AND SIGNALING Cell wall/membrane/envelope biogenesis ACIAD0087 CDS +3 82926 84218 no putative UDP-glucose/GDP-mannose dehydrogenase 850 3NIGZ Belongs to the UDP-glucose GDP-mannose dehydrogenase family M CELLULAR PROCESSES AND SIGNALING Cell wall/membrane/envelope biogenesis ACIAD0088 CDS +2 84248 85279 no putative NAD-dependent epimerase/dehydratase (WbpP) 699 3NK1T 3-beta hydroxysteroid dehydrogenase/isomerase family M CELLULAR PROCESSES AND SIGNALING Cell wall/membrane/envelope biogenesis ACIAD0089 CDS +1 85279 86574 no putative virulence factor MviN family (multidrug/oligosaccharidyl-lipid/polysaccharide exporter superfamily) 776 3NQK9 MviN-like protein S POORLY CHARACTERIZED Function unknown ACIAD0090 CDS +3 86571 87671 no putative glycosyl transferase family 1 711 3NMJE Glycosyltransferase Family 4 M CELLULAR PROCESSES AND SIGNALING Cell wall/membrane/envelope biogenesis ACIAD0091 CDS +3 87684 88775 no putative glycosyl transferase family 1 723 3NKJC Glycosyltransferase Family 4 M CELLULAR PROCESSES AND SIGNALING Cell wall/membrane/envelope biogenesis ACIAD0092 CDS +2 88784 89920 no putative glycosyl transferase family 1 740 3NMAJ Glycosyl transferases group 1 M CELLULAR PROCESSES AND SIGNALING Cell wall/membrane/envelope biogenesis ACIAD0093 CDS +1 89914 90528 no putative UDP-galactose phosphate transferase (WeeH) 409 3NKCB Bacterial sugar transferase M CELLULAR PROCESSES AND SIGNALING Cell wall/membrane/envelope biogenesis ACIAD0094 CDS +2 90509 91195 no putative acetyltransferase (WeeI) 439 3NKV7 maltose O-acetyltransferase activity S POORLY CHARACTERIZED Function unknown ACIAD0095 CDS +2 91199 92374 no per perosamine synthetase (WeeJ) 802 3NKI3 Belongs to the DegT DnrJ EryC1 family E METABOLISM Amino acid transport and metabolism ACIAD0096 CDS +3 92376 94265 no putative dTDP-glucose-4,6-dehydratase/UDP-glucose 4-epimerase (WeeK) (WbpM) 1160 3NIY7 RmlD substrate binding domain G METABOLISM Carbohydrate transport and metabolism ACIAD0096 CDS +3 92376 94265 no putative dTDP-glucose-4,6-dehydratase/UDP-glucose 4-epimerase (WeeK) (WbpM) 1160 3NIY7 RmlD substrate binding domain M CELLULAR PROCESSES AND SIGNALING Cell wall/membrane/envelope biogenesis ACIAD0098 CDS +2 94679 96043 no putative UDP-glucose lipid carrier transferase/glucose-1-phosphate transferase in colanic acid gene cluster (WcaJ) 868 3NKCB Bacterial sugar transferase M CELLULAR PROCESSES AND SIGNALING Cell wall/membrane/envelope biogenesis ACIAD0099 CDS +3 96123 97010 no galU UTP-glucose-1-phosphate uridylyltransferase 571 3NKR1 UTP-glucose-1-phosphate uridylyltransferase M CELLULAR PROCESSES AND SIGNALING Cell wall/membrane/envelope biogenesis ACIAD0100 CDS +2 97037 98308 no putative UDP-glucose 6-dehydrogenase (Ugd) (Udg) 856 3NJGE Belongs to the UDP-glucose GDP-mannose dehydrogenase family M CELLULAR PROCESSES AND SIGNALING Cell wall/membrane/envelope biogenesis ACIAD0101 CDS +1 98305 99978 no pgi glucose-6-phosphate isomerase 1128 3NIPF Belongs to the GPI family G METABOLISM Carbohydrate transport and metabolism ACIAD0102 CDS +2 99971 100990 no galE UDP-glucose 4-epimerase (Galactowaldenase) (UDP-galactose 4-epimerase) 679 3NII4 UDP-glucose 4-epimerase M CELLULAR PROCESSES AND SIGNALING Cell wall/membrane/envelope biogenesis ACIAD0103 CDS +2 101027 102733 no pglL O-oligosaccharyltransferase 1112 3NIXG macromolecule glycosylation M CELLULAR PROCESSES AND SIGNALING Cell wall/membrane/envelope biogenesis ACIAD0104 CDS -3 102792 104165 no manB bifunctional protein [Includes: phosphomannomutase (Pmm); putative phosphoglucomutase (Glucose phosphomutase) (Pgm)] 922 3NIJX Phosphoglucomutase/phosphomannomutase, C-terminal domain G METABOLISM Carbohydrate transport and metabolism ACIAD0105 CDS -2 104308 105207 no putative transcriptional regulator (LysR family) 602 3NJAI LysR substrate binding domain K INFORMATION STORAGE AND PROCESSING Transcription ACIAD0106 CDS +2 105761 107416 no lldP L-lactate permease 1051 3NJK8 L-lactate permease C METABOLISM Energy production and conversion ACIAD0107 CDS +1 107440 108192 no lldR transcriptional repressor for L-lactate utilization (GntR family) 475 3NTA3 FCD K INFORMATION STORAGE AND PROCESSING Transcription ACIAD0108 CDS +3 108189 109343 no lldD L-lactate dehydrogenase, FMN linked 764 3NJCA Catalyzes the conversion of L-lactate to pyruvate. Is coupled to the respiratory chain C METABOLISM Energy production and conversion ACIAD0109 CDS +3 109347 111065 no dld D-lactate dehydrogenase, NADH independent, FAD-binding domain 1145 3NIS1 Catalyzes the oxidation of D-lactate to pyruvate C METABOLISM Energy production and conversion ACIAD0110 CDS +1 111193 112650 no conserved hypothetical protein; putative signal peptide 988 3NJKV Capsule assembly protein Wzi P METABOLISM Inorganic ion transport and metabolism ACIAD0111 CDS -2 112714 112977 no conserved hypothetical protein; putative membrane protein 181 3NRT6 Sugar efflux transporter for intercellular exchange S POORLY CHARACTERIZED Function unknown ACIAD0112 CDS -2 113131 114345 no tyrB tyrosine aminotransferase, tyrosine repressible, PLP-dependent 811 3NJRT Aminotransferase class I and II E METABOLISM Amino acid transport and metabolism ACIAD0114 CDS -2 115051 115521 no dadR transcriptional regulator for dadAX gene cluster (AsnC family) 300 3NKY4 Lrp/AsnC ligand binding domain K INFORMATION STORAGE AND PROCESSING Transcription ACIAD0115 CDS +1 115660 116919 no dadA D-amino acid dehydrogenase, small subunit 833 3NITY Oxidative deamination of D-amino acids C METABOLISM Energy production and conversion ACIAD0116 CDS +2 116951 118048 no dadX alanine racemase 2, PLP-binding, catabolic 736 3NJK5 Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids E METABOLISM Amino acid transport and metabolism ACIAD0117 CDS +1 118060 118419 no conserved hypothetical protein; putative endoribonuclease L-PSP 231 3NNHV Endoribonuclease L-PSP J INFORMATION STORAGE AND PROCESSING Translation, ribosomal structure and biogenesis ACIAD0118 CDS +2 118673 120052 no cycA APC family, D-serine/D-alanine/glycine transport protein 884 3NJUE Amino acid permease E METABOLISM Amino acid transport and metabolism ACIAD0119 CDS +3 120579 121100 no putative major fimbrial subunit protein precursor 308 3NNUZ Fimbrial protein N CELLULAR PROCESSES AND SIGNALING Cell motility ACIAD0119 CDS +3 120579 121100 no putative major fimbrial subunit protein precursor 308 3NNUZ Fimbrial protein U CELLULAR PROCESSES AND SIGNALING Intracellular trafficking, secretion, and vesicular transport ACIAD0120 CDS +3 121215 121931 no putative pili assembly chaperone, required for type 1 fimbriae 477 3NN8Q Pili assembly chaperone PapD, C-terminal domain N CELLULAR PROCESSES AND SIGNALING Cell motility ACIAD0120 CDS +3 121215 121931 no putative pili assembly chaperone, required for type 1 fimbriae 477 3NN8Q Pili assembly chaperone PapD, C-terminal domain U CELLULAR PROCESSES AND SIGNALING Intracellular trafficking, secretion, and vesicular transport ACIAD0121 CDS +3 121944 124553 no putative outer membrane usher protein (probable fimbrial usher protein) 1743 3NM2C usher protein N CELLULAR PROCESSES AND SIGNALING Cell motility ACIAD0121 CDS +3 121944 124553 no putative outer membrane usher protein (probable fimbrial usher protein) 1743 3NM2C usher protein U CELLULAR PROCESSES AND SIGNALING Intracellular trafficking, secretion, and vesicular transport ACIAD0122 CDS +3 124554 125978 no putative fimbrial subunit, outer membrane protein 946 3NMY6 Fimbrial protein N CELLULAR PROCESSES AND SIGNALING Cell motility ACIAD0122 CDS +3 124554 125978 no putative fimbrial subunit, outer membrane protein 946 3NMY6 Fimbrial protein U CELLULAR PROCESSES AND SIGNALING Intracellular trafficking, secretion, and vesicular transport ACIAD0123 CDS +2 125975 126712 no putative pili assembly chaperone 489 3NNNM Pili assembly chaperone PapD, C-terminal domain M CELLULAR PROCESSES AND SIGNALING Cell wall/membrane/envelope biogenesis ACIAD0124 CDS +3 126867 127841 no putative transcriptional regulator 651 3NKAH Arabinose-binding domain of AraC transcription regulator, N-term K INFORMATION STORAGE AND PROCESSING Transcription ACIAD0125 CDS -3 128001 128885 no conserved hypothetical protein; putative membrane protein 577 3NJPE EamA-like transporter family E METABOLISM Amino acid transport and metabolism ACIAD0125 CDS -3 128001 128885 no conserved hypothetical protein; putative membrane protein 577 3NJPE EamA-like transporter family G METABOLISM Carbohydrate transport and metabolism ACIAD0126 CDS -3 128937 130484 no garD D-galactarate dehydratase 1016 3NM7S D-galactarate dehydratase / Altronate hydrolase, C terminus G METABOLISM Carbohydrate transport and metabolism ACIAD0127 CDS -1 130553 131836 no gudP D-glucarate/D-galactarate permease (MFS superfamily) 830 3NM7X Major Facilitator Superfamily G METABOLISM Carbohydrate transport and metabolism ACIAD0128 CDS +2 132209 133543 no gudD D-glucarate dehydratase 911 3NJYV Mandelate racemase / muconate lactonizing enzyme, C-terminal domain H METABOLISM Coenzyme transport and metabolism ACIAD0130 CDS +1 134254 135165 no kdgD 5-dehydro-4-deoxyglucarate dehydratase (5-keto-4-deoxy- glucarate dehydratase) 597 3NIFI Belongs to the DapA family E METABOLISM Amino acid transport and metabolism ACIAD0130 CDS +1 134254 135165 no kdgD 5-dehydro-4-deoxyglucarate dehydratase (5-keto-4-deoxy- glucarate dehydratase) 597 3NIFI Belongs to the DapA family M CELLULAR PROCESSES AND SIGNALING Cell wall/membrane/envelope biogenesis ACIAD0131 CDS +3 135198 136778 no 2-ketoglutarate semialdehyde dehydrogenase 1017 3NM93 Aldehyde dehydrogenase family C METABOLISM Energy production and conversion ACIAD0132 CDS +2 136994 137707 no putative transcriptional regulator (GntR family) 441 3NMCP FCD K INFORMATION STORAGE AND PROCESSING Transcription ACIAD0133 CDS -1 137774 138742 no putative 2-hydroxyacid dehydrogenase 639 3NM6Z Evidence 3 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology C METABOLISM Energy production and conversion ACIAD0134 CDS +1 138808 138975 partial fragment of transposase 83.6 1RQSR cog cog2801 L INFORMATION STORAGE AND PROCESSING Replication, recombination and repair ACIAD0135 CDS +2 139127 140170 no putative transcriptional repressor (GalR/LacI family) 668 3NPPB helix_turn _helix lactose operon repressor K INFORMATION STORAGE AND PROCESSING Transcription ACIAD0136 CDS +3 140409 141734 no putative xanthine/uracil permease 816 3NR0W Permease family F METABOLISM Nucleotide transport and metabolism ACIAD0137 CDS +1 141745 143175 no putative midohydrolase-related domain-containing protein 945 3NKU6 Amidohydrolase family F METABOLISM Nucleotide transport and metabolism ACIAD0138 CDS +3 143172 143894 no conserved hypothetical protein; putative membrane protein 444 3NRA7 Sulfite exporter TauE/SafE S POORLY CHARACTERIZED Function unknown ACIAD0139 CDS +1 143959 145248 no putative outer membrane protein 866 1T2BF Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane M CELLULAR PROCESSES AND SIGNALING Cell wall/membrane/envelope biogenesis ACIAD0142 CDS +2 145763 146071 no putative activator of morphogenic pathway (BolA) , important in general stress response 206 3NNZS Belongs to the BolA IbaG family T CELLULAR PROCESSES AND SIGNALING Signal transduction mechanisms ACIAD0143 CDS +1 146083 146475 no putative membrane protein 234 3NNWD Invasion gene expression up-regulator, SirB S POORLY CHARACTERIZED Function unknown ACIAD0144 CDS +1 146557 147396 no putative ATPase involved in chromosome partitioning (ParA family ATPase) 542 3NJ53 Anion-transporting ATPase D CELLULAR PROCESSES AND SIGNALING Cell cycle control, cell division, chromosome partitioning ACIAD0145 CDS +2 147389 147796 no putative lipoprotein 211 3NNDM S POORLY CHARACTERIZED Function unknown ACIAD0147 CDS +1 148006 148596 no putative amino acid transporter 392 3NJWA lysine exporter protein (LysE YggA) E METABOLISM Amino acid transport and metabolism ACIAD0148 CDS -3 148593 149279 no putative integral membrane protein (DedA) 446 3NIY9 SNARE associated Golgi protein S POORLY CHARACTERIZED Function unknown ACIAD0149 CDS +1 149443 149865 no putative DoxX family protein 271 3NN46 DoxX S POORLY CHARACTERIZED Function unknown ACIAD0150 CDS +2 149978 150346 no conserved hypothetical protein (OB-fold domain-containing protein) 237 3NNK8 Bacterial OB fold (BOF) protein S POORLY CHARACTERIZED Function unknown ACIAD0151 CDS +1 150400 152052 no guaA GMP synthetase (glutamine aminotransferase) 1098 3NJGP Catalyzes the synthesis of GMP from XMP F METABOLISM Nucleotide transport and metabolism ACIAD0152 CDS -1 152162 154642 no putative P-loop domain-containing protein 1570 3NMUT AAA domain S POORLY CHARACTERIZED Function unknown ACIAD0154 CDS +2 154811 155338 no putative transcriptional regulator 332 3NK1B Transcriptional regulator PadR-like family K INFORMATION STORAGE AND PROCESSING Transcription ACIAD0155 CDS +2 155372 155689 no conserved hypothetical protein (DUF3861) 210 3NP2N Domain of Unknown Function with PDB structure (DUF3861) S POORLY CHARACTERIZED Function unknown ACIAD0156 CDS +2 155705 155944 no conserved hypothetical protein; putative membrane protein 105 3NPWX Protein of unknown function (DUF2798) S POORLY CHARACTERIZED Function unknown ACIAD0157 CDS +2 156095 157042 no conserved hypothetical protein; pirin-related protein 660 3NIK3 Belongs to the pirin family S POORLY CHARACTERIZED Function unknown ACIAD0158 CDS +1 157039 157437 no putative OsmC-like family protein 266 3NN9I OsmC-like protein O CELLULAR PROCESSES AND SIGNALING Posttranslational modification, protein turnover, chaperones ACIAD0159 CDS +3 157503 158186 no glutathione S-transferase 448 3NK88 Glutathione S-transferase O CELLULAR PROCESSES AND SIGNALING Posttranslational modification, protein turnover, chaperones ACIAD0160 CDS -1 158189 159055 no putative transcriptional regulator (AraC family) 595 3NJ59 helix_turn_helix, arabinose operon control protein K INFORMATION STORAGE AND PROCESSING Transcription ACIAD0161 CDS +1 159232 160149 no putative transporter 599 3NJKK EamA-like transporter family E METABOLISM Amino acid transport and metabolism ACIAD0161 CDS +1 159232 160149 no putative transporter 599 3NJKK EamA-like transporter family G METABOLISM Carbohydrate transport and metabolism ACIAD0162 CDS +1 160225 161481 no Putative nuclease 848 3NMPP Putative ParB-like nuclease S POORLY CHARACTERIZED Function unknown ACIAD0163 CDS -1 161540 162142 no putative peptidoglycan binding protein 389 3NIZX Sporulation related domain D CELLULAR PROCESSES AND SIGNALING Cell cycle control, cell division, chromosome partitioning ACIAD0164 CDS -3 162258 164048 no argS arginyl-tRNA synthetase 1163 3NK37 Arginyl-tRNA synthetase J INFORMATION STORAGE AND PROCESSING Translation, ribosomal structure and biogenesis ACIAD0165 CDS -1 164201 164791 no hypothetical protein 391 3NP3V S POORLY CHARACTERIZED Function unknown ACIAD0166 CDS +2 165044 166744 no sfcA NAD-linked malate dehydrogenase, Rossman fold 1129 3NIZP malate dehydrogenase (decarboxylating) (NAD+) activity C METABOLISM Energy production and conversion ACIAD0167 CDS +2 166880 170200 no putative VGR-related protein 2031 3NIE7 Phage late control gene D protein (GPD) S POORLY CHARACTERIZED Function unknown ACIAD0168 CDS +1 170197 172380 no LysM domain-containing protein 1431 3NMQ7 Lysin motif M CELLULAR PROCESSES AND SIGNALING Cell wall/membrane/envelope biogenesis ACIAD0169 CDS +2 172382 173107 no putative lipoprotein 481 3NJ3Y S POORLY CHARACTERIZED Function unknown ACIAD0172 CDS -1 173609 174532 no conserved hypothetical protein; putative dyp-type peroxidase 611 3NK2T Dyp-type peroxidase family P METABOLISM Inorganic ion transport and metabolism ACIAD0173 CDS +2 174698 175324 no rhtB homoserine/homoserine lactone efflux protein 403 3NIVK LysE type translocator E METABOLISM Amino acid transport and metabolism ACIAD0174 CDS -2 175327 176142 no znuB high affinity Zn transport protein (ABC superfamily, membrane) 514 3NJST ABC 3 transport family P METABOLISM Inorganic ion transport and metabolism ACIAD0175 CDS -3 176145 176924 no znuC high affinity Zn transport protein (ABC superfamily, atp_bind) 523 3NJ9Z Part of the ABC transporter complex ZnuABC involved in zinc import. Responsible for energy coupling to the transport system P METABOLISM Inorganic ion transport and metabolism ACIAD0176 CDS -1 176915 177403 no zur transcriptional repressor of Zn transport system (Fur family) 331 3NJTB Belongs to the Fur family P METABOLISM Inorganic ion transport and metabolism ACIAD0177 CDS +1 177514 178368 no znuA high affinity Zn transport protein (ABC superfamily, peri_bind) 569 3NJWZ Zinc-uptake complex component A periplasmic P METABOLISM Inorganic ion transport and metabolism ACIAD0178 CDS +3 178542 178940 no atpI ATP synthase protein I 252 3NNM6 ATP synthase I chain C METABOLISM Energy production and conversion ACIAD0180 CDS +1 179044 179919 no atpB membrane-bound ATP synthase, F0 sector, subunit a, important for FO assembly 571 3NJCY it plays a direct role in the translocation of protons across the membrane C METABOLISM Energy production and conversion ACIAD0182 CDS +1 180004 180249 no atpE membrane-bound ATP synthase, F0 sector, subunit c 147 3NPA2 F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation C METABOLISM Energy production and conversion ACIAD0183 CDS +1 180289 180759 no atpF membrane-bound ATP synthase, F0 sector, subunit b 168 3NJBM Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0) C METABOLISM Energy production and conversion ACIAD0184 CDS +3 180771 181307 no atpH membrane-bound ATP synthase , F1 sector, delta-subunit 328 3NIHZ F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation C METABOLISM Energy production and conversion ACIAD0185 CDS +3 181338 182897 no atpA membrane-bound ATP synthase , F1 sector, alpha-subunit 988 3NJ2E Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit C METABOLISM Energy production and conversion ACIAD0186 CDS +2 182975 183844 no atpG membrane-bound ATP synthase , F1 sector, gamma-subunit 549 3NJVA Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex C METABOLISM Energy production and conversion ACIAD0187 CDS +2 183875 185269 no atpD membrane-bound ATP synthase , F1 sector, beta-subunit 900 3NK1R Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits C METABOLISM Energy production and conversion ACIAD0188 CDS +2 185297 185716 no atpC membrane-bound ATP synthase , F1 sector, epsilon-subunit 259 3NN50 Produces ATP from ADP in the presence of a proton gradient across the membrane C METABOLISM Energy production and conversion ACIAD0189 CDS +1 185860 186339 no conserved hypothetical protein DUF2846 318 3NNCQ Protein of unknown function (DUF2846) S POORLY CHARACTERIZED Function unknown ACIAD0190 CDS +1 186460 186768 no conserved hypothetical protein 202 3NQ35 S POORLY CHARACTERIZED Function unknown ACIAD0191 CDS +1 186781 187665 no putative aldose 1-epimerase family protein 594 3NMHJ Belongs to the glucose-6-phosphate 1-epimerase family G METABOLISM Carbohydrate transport and metabolism ACIAD0192 CDS -2 187684 188271 no conserved hypothetical protein 355 3NNI2 S POORLY CHARACTERIZED Function unknown ACIAD0193 CDS -3 188463 189008 no glutathione peroxidase 378 3NKR3 Glutathione peroxidase O CELLULAR PROCESSES AND SIGNALING Posttranslational modification, protein turnover, chaperones ACIAD0194 CDS -3 189144 189923 no putative transcriptional regulator (AraC family) 524 3NTAS helix_turn_helix, arabinose operon control protein K INFORMATION STORAGE AND PROCESSING Transcription ACIAD0195 CDS -3 189942 191147 no putative transporter (MFS superfamily) 758 3NSWZ Major Facilitator Superfamily E METABOLISM Amino acid transport and metabolism ACIAD0195 CDS -3 189942 191147 no putative transporter (MFS superfamily) 758 3NSWZ Major Facilitator Superfamily G METABOLISM Carbohydrate transport and metabolism ACIAD0195 CDS -3 189942 191147 no putative transporter (MFS superfamily) 758 3NSWZ Major Facilitator Superfamily P METABOLISM Inorganic ion transport and metabolism ACIAD0196 CDS +2 191273 191977 no putative regulator (TetR/AcrR family) 460 3NTAT Bacterial regulatory proteins, tetR family K INFORMATION STORAGE AND PROCESSING Transcription ACIAD0197 CDS +1 192055 192966 no putative membrane protein 585 3NIXW EamA-like transporter family E METABOLISM Amino acid transport and metabolism ACIAD0197 CDS +1 192055 192966 no putative membrane protein 585 3NIXW EamA-like transporter family G METABOLISM Carbohydrate transport and metabolism ACIAD0198 CDS +1 193384 194565 no putative membrane lipoprotein 780 3NM9M ABC transporter substrate-binding protein PnrA-like S POORLY CHARACTERIZED Function unknown ACIAD0199 CDS +1 194599 195249 no putative oxidoreductase protein 451 3NMFF Rieske [2Fe-2S] domain P METABOLISM Inorganic ion transport and metabolism ACIAD0200 CDS +2 195242 196132 no conserved hypothetical protein; putative ferredoxin subunit of nitrite reductase and ring-hydroxylating dioxygenase 602 3NKC1 Rieske (2fe-2S) P METABOLISM Inorganic ion transport and metabolism ACIAD0201 CDS +1 196129 196749 no putative Glutathione S-transferase-like protein (Gst13 glutathione S-transferase) 420 3NMYD glutathione transferase activity O CELLULAR PROCESSES AND SIGNALING Posttranslational modification, protein turnover, chaperones ACIAD0202 CDS +3 196911 197858 no putative transcriptional regulator (LysR family) 631 3NT7R LysR substrate binding domain K INFORMATION STORAGE AND PROCESSING Transcription ACIAD0203 CDS +2 198110 199393 no putative membrane protein 879 3NM4M S POORLY CHARACTERIZED Function unknown ACIAD0204 CDS +2 199469 200023 no putative cytidine and deoxycytidylate deaminase zinc-binding like protein 381 3NSRJ MafB19-like deaminase F METABOLISM Nucleotide transport and metabolism ACIAD0204 CDS +2 199469 200023 no putative cytidine and deoxycytidylate deaminase zinc-binding like protein 381 3NSRJ MafB19-like deaminase J INFORMATION STORAGE AND PROCESSING Translation, ribosomal structure and biogenesis ACIAD0205 CDS +1 200065 201624 no putative sugar transport protein (ABC superfamily atp_bind) 988 3NJ3U ABC transporter S POORLY CHARACTERIZED Function unknown ACIAD0206 CDS +1 201649 202770 no putative transport protein (ABC superfamily, membrane) 727 3NMIR Branched-chain amino acid transport system / permease component S POORLY CHARACTERIZED Function unknown ACIAD0207 CDS +1 202783 203700 no putative transport protein (ABC superfamily, membrane) 540 3NKFN Branched-chain amino acid transport system / permease component S POORLY CHARACTERIZED Function unknown ACIAD0208 CDS -1 204236 204814 no putative ribosome maturation factor (dsRNA-binding protein) (RimN) 387 3NKGI Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Catalyzes the conversion of L-threonine, HCO(3)(-) CO(2) and ATP to give threonylcarbamoyl-AMP (TC-AMP) as the acyladenylate intermediate, with the release of diphosphate J INFORMATION STORAGE AND PROCESSING Translation, ribosomal structure and biogenesis ACIAD0209 CDS -1 204848 205999 no putative Rossmann-fold nucleotide-binding protein involved in DNA uptake (Smf) 776 3NJFR nucleotide-binding protein involved in DNA uptake L INFORMATION STORAGE AND PROCESSING Replication, recombination and repair ACIAD0209 CDS -1 204848 205999 no putative Rossmann-fold nucleotide-binding protein involved in DNA uptake (Smf) 776 3NJFR nucleotide-binding protein involved in DNA uptake U CELLULAR PROCESSES AND SIGNALING Intracellular trafficking, secretion, and vesicular transport ACIAD0210 CDS -2 206017 207180 no putative peptidoglycan-binding LysM domain 780 3NJMD LysM domain S POORLY CHARACTERIZED Function unknown ACIAD0211 CDS +1 207295 207819 no def peptide deformylase 1 (N-formylmethionylaminoacyl-tRNA deformylase, binds Zn(II)) 333 3NKDT Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions J INFORMATION STORAGE AND PROCESSING Translation, ribosomal structure and biogenesis ACIAD0212 CDS +1 207853 208335 no putative DUF2946 domain-containing membrane protein 315 3NN6H S POORLY CHARACTERIZED Function unknown ACIAD0214 CDS +1 208438 210426 no putative outer membrane copper receptor (OprC) 1344 3NIWK TonB dependent receptor M CELLULAR PROCESSES AND SIGNALING Cell wall/membrane/envelope biogenesis ACIAD0215 CDS +3 210474 210797 no conserved hypothetical protein 197 3NPCX S POORLY CHARACTERIZED Function unknown ACIAD0216 CDS -3 210837 212042 no putative DUF2236 domain-containing protein 813 3NMED Uncharacterized protein conserved in bacteria (DUF2236) S POORLY CHARACTERIZED Function unknown ACIAD0217 CDS +1 212128 212721 no putative HTH-type transcription regulator protein (TetR family) 385 3NM2Y Bacterial regulatory proteins, tetR family K INFORMATION STORAGE AND PROCESSING Transcription ACIAD0219 CDS +2 218687 219331 no putative hydrolase 434 3NPMQ S POORLY CHARACTERIZED Function unknown ACIAD0220 CDS +3 219537 221939 no putative UPF0313 SAM protein 1613 3NJH5 UPF0313 protein C METABOLISM Energy production and conversion ACIAD0221 CDS +1 222331 222849 no putative DUF2726 domain-containing protein 340 3NK28 Protein of unknown function (DUF2726) S POORLY CHARACTERIZED Function unknown ACIAD0222 CDS -2 222850 223203 no putative RidA family protein 233 3NNI5 Endoribonuclease L-PSP J INFORMATION STORAGE AND PROCESSING Translation, ribosomal structure and biogenesis ACIAD0223 CDS -2 223204 224541 no shiA shikimate and dehydroshikimate transport protein (MFS superfamily) 875 3NKDF Sugar (and other) transporter E METABOLISM Amino acid transport and metabolism ACIAD0223 CDS -2 223204 224541 no shiA shikimate and dehydroshikimate transport protein (MFS superfamily) 875 3NKDF Sugar (and other) transporter G METABOLISM Carbohydrate transport and metabolism ACIAD0223 CDS -2 223204 224541 no shiA shikimate and dehydroshikimate transport protein (MFS superfamily) 875 3NKDF Sugar (and other) transporter P METABOLISM Inorganic ion transport and metabolism ACIAD0225 CDS -1 224762 225817 no dinP DNA polymerase IV, devoid of proofreading, damage-inducible protein P 688 3NJQG Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII L INFORMATION STORAGE AND PROCESSING Replication, recombination and repair ACIAD0226 CDS -2 225814 226608 no putative lysozyme 550 3NIEB Glycosyl hydrolases family 25 M CELLULAR PROCESSES AND SIGNALING Cell wall/membrane/envelope biogenesis ACIAD0228 CDS -3 226650 228047 no putative transport protein (MFS superfamily) 890 3NJC0 Transmembrane secretion effector U CELLULAR PROCESSES AND SIGNALING Intracellular trafficking, secretion, and vesicular transport ACIAD0229 CDS -3 228177 228794 no conserved hypothetical protein 406 3NIUZ Possible lysine decarboxylase S POORLY CHARACTERIZED Function unknown ACIAD0230 CDS +2 229124 230719 no putative CBS domain-containing membrane protein 1011 3NIPV Transporter associated domain P METABOLISM Inorganic ion transport and metabolism ACIAD0231 CDS +3 230775 231251 no conserved hypothetical protein 330 3NN2B SEC-C motif S POORLY CHARACTERIZED Function unknown ACIAD0232 CDS +3 231300 231944 no putative membrane protein 416 3NJHG UPF0126 domain S POORLY CHARACTERIZED Function unknown ACIAD0233 CDS +3 232176 233495 no niaP niacin transporer 870 3NKDC Sugar (and other) transporter E METABOLISM Amino acid transport and metabolism ACIAD0233 CDS +3 232176 233495 no niaP niacin transporer 870 3NKDC Sugar (and other) transporter G METABOLISM Carbohydrate transport and metabolism ACIAD0233 CDS +3 232176 233495 no niaP niacin transporer 870 3NKDC Sugar (and other) transporter P METABOLISM Inorganic ion transport and metabolism ACIAD0234 CDS +1 233653 235869 no parC DNA topoisomerase IV, subunit A 1411 3NIU5 Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule L INFORMATION STORAGE AND PROCESSING Replication, recombination and repair ACIAD0235 CDS +3 236016 237695 no fadD acyl-CoA synthetase (long-chain-fatty-acid--CoA ligase) 1113 3NK11 COG0318 Acyl-CoA synthetases (AMP-forming) AMP-acid ligases II I METABOLISM Lipid transport and metabolism ACIAD0235 CDS +3 236016 237695 no fadD acyl-CoA synthetase (long-chain-fatty-acid--CoA ligase) 1113 3NK11 COG0318 Acyl-CoA synthetases (AMP-forming) AMP-acid ligases II Q METABOLISM Secondary metabolites biosynthesis, transport and catabolism ACIAD0236 CDS -2 237751 238161 no conserved hypothetical protein; putative membrane protein 267 3NNBW S POORLY CHARACTERIZED Function unknown ACIAD0237 CDS +3 238242 238640 no putative MAPEG family membrane protein 241 3NNNN MAPEG family S POORLY CHARACTERIZED Function unknown ACIAD0239 CDS +3 238767 239294 no ppa inorganic pyrophosphatase 356 3NJX9 Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions C METABOLISM Energy production and conversion ACIAD0240 CDS -3 239385 240686 no oprD carbapenem-associated resistance protein 877 3NJ37 outer membrane porin, OprD family S POORLY CHARACTERIZED Function unknown ACIAD0241 CDS +1 241309 242133 no putative signal peptide protein 534 3NT65 Bacterial protein of unknown function (Gcw_chp) S POORLY CHARACTERIZED Function unknown ACIAD0242 CDS -3 242202 243689 no magnesium chelatase, competence related protein (ComM) 963 3NIII Magnesium chelatase, subunit ChlI O CELLULAR PROCESSES AND SIGNALING Posttranslational modification, protein turnover, chaperones ACIAD0243 CDS -3 243759 244052 no conserved hypothetical protein 169 3NPB8 Membrane fusogenic activity S POORLY CHARACTERIZED Function unknown ACIAD0244 CDS +1 244264 244602 no glnK regulatory protein, P-II 2, for nitrogen assimilation by glutamine synthetase, regulates GlnL (NRII) and GlnE (ATase) 214 3NNHG Belongs to the P(II) protein family K INFORMATION STORAGE AND PROCESSING Transcription ACIAD0245 CDS +2 244664 246064 no amtB ammonium transport protein (Amt family) 842 3NIJV Ammonium Transporter Family P METABOLISM Inorganic ion transport and metabolism ACIAD0246 CDS +1 246187 246666 no nrdR Transcriptional repressor nrdR 308 3NJDY Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes K INFORMATION STORAGE AND PROCESSING Transcription ACIAD0247 CDS +2 246659 247747 no ribD bifunctional protein [Includes: diaminohydroxyphosphoribosylaminopyrimidine deaminase (Riboflavin-specific deaminase); 5-amino-6-(5- phosphoribosylamino)uracil reductase (HTP reductase) ] 709 3NJDK Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate H METABOLISM Coenzyme transport and metabolism ACIAD0248 CDS +1 247744 249039 no putative DNA modification methylase (Adenine-specific methyltransferase) 884 3NJQR D12 class N6 adenine-specific DNA methyltransferase L INFORMATION STORAGE AND PROCESSING Replication, recombination and repair ACIAD0249 CDS +3 249084 249743 no ribC riboflavin synthase alpha chain 434 3NJ7N Lumazine binding domain H METABOLISM Coenzyme transport and metabolism ACIAD0250 CDS -1 249791 250009 no conserved hypothetical protein 144 3NPU1 S POORLY CHARACTERIZED Function unknown ACIAD0251 CDS -2 250132 250764 no conserved hypothetical protein 383 3NJD9 S POORLY CHARACTERIZED Function unknown ACIAD0252 CDS -3 250800 251207 no holC DNA polymerase III, chi subunit 276 3NNGG DNA polymerase III, chi subunit L INFORMATION STORAGE AND PROCESSING Replication, recombination and repair ACIAD0253 CDS -2 251200 252648 no pepA aminopeptidase A 939 3NJ24 Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides E METABOLISM Amino acid transport and metabolism ACIAD0254 CDS +2 252803 253903 no putative lipopolysaccharide permease 691 3NIPZ Predicted permease YjgP/YjgQ family S POORLY CHARACTERIZED Function unknown ACIAD0255 CDS +1 253903 254973 no putative lipopolysaccharide permease 685 3NJZ3 Predicted permease YjgP/YjgQ family S POORLY CHARACTERIZED Function unknown ACIAD0256 CDS +2 255095 256642 no gpmI 2,3-bisphosphoglycerate-independent phosphoglycerate mutase 1015 3NJ0F Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate G METABOLISM Carbohydrate transport and metabolism ACIAD0257 CDS +3 256653 257834 no putative periplasmic carboxyl-terminal protease 770 3NJR0 tail specific protease M CELLULAR PROCESSES AND SIGNALING Cell wall/membrane/envelope biogenesis ACIAD0258 CDS -2 257836 259251 no pilR type 4 fimbriae expression regulatory protein 931 3NK7Z Sigma-54 interaction domain T CELLULAR PROCESSES AND SIGNALING Signal transduction mechanisms ACIAD0259 CDS -3 259269 260849 no pilS sensor protein 1003 3NJAQ PAS domain T CELLULAR PROCESSES AND SIGNALING Signal transduction mechanisms ACIAD0260 CDS -3 260868 261503 no gacA response regulator (Global antibiotic and cyanide control protein, LuxR/UhpA family) 401 3NJJT response regulator K INFORMATION STORAGE AND PROCESSING Transcription ACIAD0262 CDS +3 261717 262775 no pbpG D-alanyl-D-alanine endopeptidase, penicillin-binding protein 7 and penicillin-binding protein 8 643 3NK5B Belongs to the peptidase S11 family M CELLULAR PROCESSES AND SIGNALING Cell wall/membrane/envelope biogenesis ACIAD0263 CDS -3 262869 264008 no thrC threonine synthase, pyridoxal-5'-phosphate-dependent enzyme 740 3NIF7 Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine E METABOLISM Amino acid transport and metabolism ACIAD0264 CDS -3 264069 265382 no hom homoserine dehydrogenase 834 3NKC8 homoserine dehydrogenase E METABOLISM Amino acid transport and metabolism ACIAD0265 CDS -2 265546 266358 no dsbC thiol:disulfide interchange protein 533 3NK0T Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process O CELLULAR PROCESSES AND SIGNALING Posttranslational modification, protein turnover, chaperones ACIAD0266 CDS -2 266488 267405 no xerD site-specific tyrosine recombinase 600 3NIQA recombinase XerD D CELLULAR PROCESSES AND SIGNALING Cell cycle control, cell division, chromosome partitioning ACIAD0267 CDS +3 267558 267821 no putative ferrous iron transport protein A (FeoA) 171 3NPHZ FeoA P METABOLISM Inorganic ion transport and metabolism ACIAD0268 CDS +2 267818 269671 no putative ferrous iron transport protein B (FeoB) 1189 3NK9Z Ferrous iron transport protein B P METABOLISM Inorganic ion transport and metabolism ACIAD0269 CDS +3 269688 269939 no conserved hypothetical protein 174 3NPII S POORLY CHARACTERIZED Function unknown ACIAD0270 CDS +2 270077 271444 no murD UDP-N-acetylmuramoylalanine-D-glutamate ligase 887 3NKJJ Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA) M CELLULAR PROCESSES AND SIGNALING Cell wall/membrane/envelope biogenesis ACIAD0271 CDS +2 271466 272665 no ftsW cell division protein, stabililzes FtsZ ring 774 3NIQ8 Peptidoglycan polymerase that is essential for cell division D CELLULAR PROCESSES AND SIGNALING Cell cycle control, cell division, chromosome partitioning ACIAD0272 CDS -3 272760 273638 no putative glutamyl t-RNA synthetase 597 3NK6Q Catalyzes the tRNA-independent activation of glutamate in presence of ATP and the subsequent transfer of glutamate onto a tRNA(Asp). Glutamate is transferred on the 2-amino-5-(4,5- dihydroxy-2-cyclopenten-1-yl) moiety of the queuosine in the wobble position of the QUC anticodon J INFORMATION STORAGE AND PROCESSING Translation, ribosomal structure and biogenesis ACIAD0273 CDS -2 273643 274182 no dksA DnaK suppressor protein 350 3NJPW Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters. Also required for regulation of fis expression T CELLULAR PROCESSES AND SIGNALING Signal transduction mechanisms ACIAD0274 CDS -1 274385 275194 no icc cyclic 3',5'-adenosine monophosphate phosphodiesterase (regulator of lacZ) 566 3NJPR Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes S POORLY CHARACTERIZED Function unknown ACIAD0275 CDS -2 275197 275817 no aspP adenosine diphosphate sugar pyrophosphatase (ADP-ribose pyrophosphatase) 409 3NIZW NUDIX domain L INFORMATION STORAGE AND PROCESSING Replication, recombination and repair ACIAD0276 CDS -2 275899 277794 no thiC hydroxymethylpyrimidine moiety synthesis in thiamin biosynthesis 1281 3NKAR Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction H METABOLISM Coenzyme transport and metabolism ACIAD0278 CDS +2 278147 279514 no tolC channel-tunnel spanning the outer membrane and periplasm segregation of daughter chromosomes 858 3NJQ1 Outer membrane efflux protein M CELLULAR PROCESSES AND SIGNALING Cell wall/membrane/envelope biogenesis ACIAD0278 CDS +2 278147 279514 no tolC channel-tunnel spanning the outer membrane and periplasm segregation of daughter chromosomes 858 3NJQ1 Outer membrane efflux protein U CELLULAR PROCESSES AND SIGNALING Intracellular trafficking, secretion, and vesicular transport ACIAD0279 CDS +2 279605 280330 no phoU transcriptional repressor for high affinity phosphate uptake 467 3NJEB Plays a role in the regulation of phosphate uptake P METABOLISM Inorganic ion transport and metabolism ACIAD0282 CDS -1 280997 281269 no Putative Fe(2+)-trafficking protein (yggX-like) 186 3NP04 Could be a mediator in iron transactions between iron acquisition and iron-requiring processes, such as synthesis and or repair of Fe-S clusters in biosynthetic enzymes C METABOLISM Energy production and conversion ACIAD0282 CDS -1 280997 281269 no Putative Fe(2+)-trafficking protein (yggX-like) 186 3NP04 Could be a mediator in iron transactions between iron acquisition and iron-requiring processes, such as synthesis and or repair of Fe-S clusters in biosynthetic enzymes O CELLULAR PROCESSES AND SIGNALING Posttranslational modification, protein turnover, chaperones ACIAD0283 CDS -1 281279 282712 no argH argininosuccinate lyase (Arginosuccinase) (ASAL) 923 3NJHZ argininosuccinate lyase E METABOLISM Amino acid transport and metabolism ACIAD0284 CDS +1 282703 283854 no algZ alginate biosynthesis protein 753 3NKZQ Histidine kinase T CELLULAR PROCESSES AND SIGNALING Signal transduction mechanisms ACIAD0285 CDS +1 283912 284652 no algR alginate biosynthesis regulatory protein 481 3NIWF LytTr DNA-binding domain K INFORMATION STORAGE AND PROCESSING Transcription ACIAD0285 CDS +1 283912 284652 no algR alginate biosynthesis regulatory protein 481 3NIWF LytTr DNA-binding domain T CELLULAR PROCESSES AND SIGNALING Signal transduction mechanisms ACIAD0286 CDS +1 284746 285681 no hemC porphobilinogen deaminase (PBG) (Hydroxymethylbilane synthase) (HMBS) (Pre-uroporphyrinogen synthase) 601 3NIRA Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps H METABOLISM Coenzyme transport and metabolism ACIAD0287 CDS +1 285688 286458 no hemD uroporphyrinogen-III synthase (UROS) (Uroporphyrinogen- III cosynthetase) (Hydroxymethylbilane hydrolyase [cyclizing]) 502 3NJF7 Uroporphyrinogen-III synthase H METABOLISM Coenzyme transport and metabolism ACIAD0288 CDS +3 286467 287297 no conserved hypothetical protein 495 3NJIT S POORLY CHARACTERIZED Function unknown ACIAD0289 CDS +3 287313 288506 no conserved hypothetical protein; putative membrane protein 781 3NIJC S POORLY CHARACTERIZED Function unknown ACIAD0290 CDS +2 288515 288955 no conserved hypothetical protein; putative thioesterase 291 3NTA5 Thioesterase-like superfamily S POORLY CHARACTERIZED Function unknown ACIAD0291 CDS +1 289162 289488 no putative DNA binding protein 204 3NNVZ Domain in histone-like proteins of HNS family S POORLY CHARACTERIZED Function unknown ACIAD0292 CDS +1 289651 290394 no putative general secretion pathway protein 496 3NK25 Type II secretion system (T2SS), protein N S POORLY CHARACTERIZED Function unknown ACIAD0293 CDS +3 290394 291239 no putative general secretion pathway protein 512 3NJJQ Type II secretion system protein C U CELLULAR PROCESSES AND SIGNALING Intracellular trafficking, secretion, and vesicular transport ACIAD0294 CDS +1 291280 293598 no putative general secretion pathway protein 1370 3NJK6 Bacterial type II and III secretion system protein N CELLULAR PROCESSES AND SIGNALING Cell motility ACIAD0294 CDS +1 291280 293598 no putative general secretion pathway protein 1370 3NJK6 Bacterial type II and III secretion system protein U CELLULAR PROCESSES AND SIGNALING Intracellular trafficking, secretion, and vesicular transport ACIAD0295 CDS +1 293665 294321 no conserved hypothetical protein 417 3NJ8C Forkhead associated domain T CELLULAR PROCESSES AND SIGNALING Signal transduction mechanisms ACIAD0296 CDS +1 294355 295059 no gph phosphoglycolate phosphatase, contains a phophatase-like domain 474 3NKK4 HAD-hyrolase-like G METABOLISM Carbohydrate transport and metabolism ACIAD0297 CDS +2 295163 296656 no trpE anthranilate synthase component I 985 3NIJW Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia E METABOLISM Amino acid transport and metabolism ACIAD0299 CDS +2 297344 298534 no tufB protein chain elongation factor EF-Tu, possible GTP-binding factor (duplicate of tufA) 788 3NIQ7 This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis J INFORMATION STORAGE AND PROCESSING Translation, ribosomal structure and biogenesis ACIAD0300 CDS +2 298742 299182 no secE preprotein translocase IISP family, membrane subunit 287 3NN4U Essential subunit of the Sec protein translocation channel SecYEG. Clamps together the 2 halves of SecY. May contact the channel plug during translocation U CELLULAR PROCESSES AND SIGNALING Intracellular trafficking, secretion, and vesicular transport ACIAD0301 CDS +3 299190 299723 no nusG transcription antitermination protein 355 3NIXF Participates in transcription elongation, termination and antitermination K INFORMATION STORAGE AND PROCESSING Transcription ACIAD0302 CDS +2 299837 300265 no rplK 50S ribosomal protein L11 275 3NJ44 Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors J INFORMATION STORAGE AND PROCESSING Translation, ribosomal structure and biogenesis ACIAD0304 CDS +2 300269 300964 no rplA 50S ribosomal protein L1 428 3NIPW Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release J INFORMATION STORAGE AND PROCESSING Translation, ribosomal structure and biogenesis ACIAD0305 CDS +1 301204 301740 no rplJ 50S ribosomal protein L10 328 3NIS4 Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors J INFORMATION STORAGE AND PROCESSING Translation, ribosomal structure and biogenesis ACIAD0306 CDS +1 301783 302148 no rplL 50S ribosomal protein L7/L12 211 3NNIS Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation J INFORMATION STORAGE AND PROCESSING Translation, ribosomal structure and biogenesis ACIAD0307 CDS +3 302457 306545 no rpoB DNA-directed RNA polymerase beta chain (Transcriptase beta chain) (RNA polymerase beta subunit) 2650 3NJ1H DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates K INFORMATION STORAGE AND PROCESSING Transcription ACIAD0308 CDS +1 306586 310827 no rpoC DNA-directed RNA polymerase beta' chain (Transcriptase beta' chain) (RNA polymerase beta' subunit) 2747 3NIMH DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates K INFORMATION STORAGE AND PROCESSING Transcription ACIAD0310 CDS +1 311074 311430 no putative exported lipoprotein 73.6 3NNIH S POORLY CHARACTERIZED Function unknown ACIAD0311 CDS -1 311477 311962 no DUF4442 domain-containing protein 327 3NN75 Domain of unknown function (DUF4442) Q METABOLISM Secondary metabolites biosynthesis, transport and catabolism ACIAD0312 CDS +2 312017 312958 no putative Alpha/beta hydrolase 649 3NTM1 Alpha/beta hydrolase family I METABOLISM Lipid transport and metabolism ACIAD0313 CDS +1 313078 314499 no putative transporter 868 3NIZY Na H antiporter S POORLY CHARACTERIZED Function unknown ACIAD0314 CDS +3 314778 315404 no putative outer membrane protein W 422 3NJEZ OmpW family M CELLULAR PROCESSES AND SIGNALING Cell wall/membrane/envelope biogenesis ACIAD0315 CDS +1 315637 315987 no conserved hypothetical protein; putative signal peptide 227 3NPEX S POORLY CHARACTERIZED Function unknown ACIAD0316 CDS +3 316092 318014 no htpG chaperone Hsp90, heat shock protein C 62.5 1238 3NIKN Molecular chaperone. Has ATPase activity O CELLULAR PROCESSES AND SIGNALING Posttranslational modification, protein turnover, chaperones ACIAD0317 CDS -3 318096 318893 no conserved hypothetical protein 536 3NKVW S POORLY CHARACTERIZED Function unknown ACIAD0318 CDS +3 319380 320090 no racD D-aspartate racemase 476 3NMUN Asp/Glu/Hydantoin racemase M CELLULAR PROCESSES AND SIGNALING Cell wall/membrane/envelope biogenesis ACIAD0319 CDS +3 320208 321506 no aspT D-aspartate transporter 783 3NKSJ Belongs to the dicarboxylate amino acid cation symporter (DAACS) (TC 2.A.23) family U CELLULAR PROCESSES AND SIGNALING Intracellular trafficking, secretion, and vesicular transport ACIAD0320 CDS +3 321630 321938 frameshift transposase of IS1236, IS3 family (ORF 1) 193 3NNW1 Evidence 1 Function experimentally demonstrated in the studied organism L INFORMATION STORAGE AND PROCESSING Replication, recombination and repair ACIAD0321 CDS +2 321947 322804 frameshift transposase of IS1236, IS3 family (ORF 2) 595 3NKN1 Evidence 1 Function experimentally demonstrated in the studied organism L INFORMATION STORAGE AND PROCESSING Replication, recombination and repair ACIAD0323 CDS -2 322807 323703 no putative transcriptional regulator (LysR family) 598 3NM9S LysR substrate binding domain K INFORMATION STORAGE AND PROCESSING Transcription ACIAD0324 CDS -3 324126 325310 no conserved hypothetical protein 794 3NJNT S POORLY CHARACTERIZED Function unknown ACIAD0328 CDS -3 325551 325781 no putative membrane protein 141 3NPW4 S POORLY CHARACTERIZED Function unknown ACIAD0330 CDS +3 326136 326363 no conserved hypothetical protein 149 3NPZ3 S POORLY CHARACTERIZED Function unknown ACIAD0331 CDS -3 326784 327491 no DSBA-like domain containing protein 462 3NSR2 DSBA-like thioredoxin domain Q METABOLISM Secondary metabolites biosynthesis, transport and catabolism ACIAD0332 CDS +2 327653 328417 no conserved hypothetical protein 481 3NKQU S POORLY CHARACTERIZED Function unknown ACIAD0333 CDS +2 328667 329164 no conserved hypothetical protein; putative signal peptide 312 3NJQI S POORLY CHARACTERIZED Function unknown ACIAD0334 CDS -3 329211 330383 no fadA 3-ketoacyl-CoA thiolase (Fatty oxidation complex beta subunit) (Beta-ketothiolase) (Acetyl-CoA acyltransferase) 754 3NK7D Catalyzes the final step of fatty acid oxidation in which acetyl-CoA is released and the CoA ester of a fatty acid two carbons shorter is formed I METABOLISM Lipid transport and metabolism ACIAD0335 CDS -2 330397 332550 no fadB fatty oxidation complex alpha subunit [Includes: Enoyl-CoA hydratase ; Delta(3)-cis-delta(2)-trans-enoyl-CoA isomerase ; 3-hydroxyacyl-CoA dehydrogenase; 3- hydroxybutyryl-CoA epimerase] 1402 3NIPR Involved in the aerobic and anaerobic degradation of long-chain fatty acids via beta-oxidation cycle. Catalyzes the formation of 3-oxoacyl-CoA from enoyl-CoA via L-3-hydroxyacyl-CoA. It can also use D-3-hydroxyacyl-CoA and cis-3-enoyl-CoA as substrate I METABOLISM Lipid transport and metabolism ACIAD0336 CDS +3 332991 333956 no conserved hypothetical protein 648 3NISB S POORLY CHARACTERIZED Function unknown ACIAD0337 CDS +3 334122 335036 no lpxO beta-hydroxylase 622 3NJ31 Aspartyl/Asparaginyl beta-hydroxylase O CELLULAR PROCESSES AND SIGNALING Posttranslational modification, protein turnover, chaperones ACIAD0339 CDS +1 335212 335769 no conserved hypothetical protein 368 3NNFJ COG3209 Rhs family protein M CELLULAR PROCESSES AND SIGNALING Cell wall/membrane/envelope biogenesis ACIAD0340 CDS +1 335860 337659 no uvrC excinuclease ABC subunit C; UvrC with UvrAB is a DNA excision repair enzyme 1178 3NIZV The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision L INFORMATION STORAGE AND PROCESSING Replication, recombination and repair ACIAD0341 CDS +1 337747 338550 no putative acyl-CoA thioesterase II 549 3NJ0J Thioesterase-like superfamily I METABOLISM Lipid transport and metabolism ACIAD0342 CDS +3 338652 339245 no pgsA CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase (Phosphatidylglycerophosphate synthase) (PGP synthase) 372 3NJ8I Belongs to the CDP-alcohol phosphatidyltransferase class-I family I METABOLISM Lipid transport and metabolism ACIAD0344 CDS +3 339360 340220 no ada bifunctional protein [Includes: transcriptional regulator of DNA repair (AraC/Xyl family); O6-methylguanine-DNA methyltransferase] 574 3NJBU 6-O-methylguanine DNA methyltransferase, DNA binding domain K INFORMATION STORAGE AND PROCESSING Transcription ACIAD0345 CDS +2 340217 340825 no alkB DNA repair system specific for alkylated DNA 418 3NKZK 2OG-Fe(II) oxygenase superfamily L INFORMATION STORAGE AND PROCESSING Replication, recombination and repair ACIAD0347 CDS -2 340879 341667 no putative transcriptional regulator 515 3NIRW Bacterial transcriptional regulator K INFORMATION STORAGE AND PROCESSING Transcription ACIAD0349 CDS +1 342115 344214 no conserved hypothetical protein; putative fusaric acid resistance protein 1310 3NJ1K Fusaric acid resistance protein family S POORLY CHARACTERIZED Function unknown ACIAD0350 CDS +2 344198 344410 no conserved hypothetical protein; putative membrane protein 148 3NPX3 Protein of unknown function (DUF1656) S POORLY CHARACTERIZED Function unknown ACIAD0351 CDS +3 344445 345461 no conserved hypothetical protein; putative fusaric acid resistance protein FusE 494 3NK4M Barrel-sandwich domain of CusB or HlyD membrane-fusion V CELLULAR PROCESSES AND SIGNALING Defense mechanisms ACIAD0352 CDS -1 345524 345967 no yqgF holliday junction resolvase yqgF-like 291 3NN70 Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA L INFORMATION STORAGE AND PROCESSING Replication, recombination and repair ACIAD0353 CDS -3 345960 346514 no protein of unknown function UPF0301 386 3NJ6B Belongs to the UPF0301 (AlgH) family K INFORMATION STORAGE AND PROCESSING Transcription ACIAD0354 CDS -2 346630 348291 no recN DNA repair protein RecN 1045 3NJAU May be involved in recombinational repair of damaged DNA L INFORMATION STORAGE AND PROCESSING Replication, recombination and repair ACIAD0355 CDS +2 348407 349714 no tetratricopeptide repeat protein 811 3NMGI Tetratricopeptide repeat S POORLY CHARACTERIZED Function unknown ACIAD0356 CDS +2 349793 350119 no ppnP Pyrimidine/purine nucleoside phosphorylase 221 3NNK2 Catalyzes the phosphorolysis of diverse nucleosides, yielding D-ribose 1-phosphate and the respective free bases. Can use uridine, adenosine, guanosine, cytidine, thymidine, inosine and xanthosine as substrates. Also catalyzes the reverse reactions S POORLY CHARACTERIZED Function unknown ACIAD0357 CDS +2 350219 350965 no putative tRNA/rRNA methyltransferase 482 3NKH2 Specifically methylates the ribose of guanosine 2251 in 23S rRNA J INFORMATION STORAGE AND PROCESSING Translation, ribosomal structure and biogenesis ACIAD0358 CDS +3 351006 351923 no putative tranporter 591 3NJPS EamA-like transporter family E METABOLISM Amino acid transport and metabolism ACIAD0358 CDS +3 351006 351923 no putative tranporter 591 3NJPS EamA-like transporter family G METABOLISM Carbohydrate transport and metabolism ACIAD0359 CDS -1 351920 352507 no coaE dephosphocoenzyme A kinase 372 3NIFP Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A H METABOLISM Coenzyme transport and metabolism ACIAD0360 CDS -2 352513 353373 no pilD type 4 prepilin-like proteins leader peptide processing enzyme (Protein secretion protein XCPA)[Includes: Leader peptidase (Prepilin peptidase); N-methyltransferase ] 574 3NJ15 Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue N CELLULAR PROCESSES AND SIGNALING Cell motility ACIAD0360 CDS -2 352513 353373 no pilD type 4 prepilin-like proteins leader peptide processing enzyme (Protein secretion protein XCPA)[Includes: Leader peptidase (Prepilin peptidase); N-methyltransferase ] 574 3NJ15 Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue O CELLULAR PROCESSES AND SIGNALING Posttranslational modification, protein turnover, chaperones ACIAD0360 CDS -2 352513 353373 no pilD type 4 prepilin-like proteins leader peptide processing enzyme (Protein secretion protein XCPA)[Includes: Leader peptidase (Prepilin peptidase); N-methyltransferase ] 574 3NJ15 Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue U CELLULAR PROCESSES AND SIGNALING Intracellular trafficking, secretion, and vesicular transport ACIAD0361 CDS -3 353373 354599 no pilC type 4 fimbrial assembly protein 761 3NIKJ Type II secretion system (T2SS), protein F U CELLULAR PROCESSES AND SIGNALING Intracellular trafficking, secretion, and vesicular transport ACIAD0362 CDS -2 354628 356367 no pilB type 4 fimbrial biogenesis protein 1101 3NIQS Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB N CELLULAR PROCESSES AND SIGNALING Cell motility ACIAD0362 CDS -2 354628 356367 no pilB type 4 fimbrial biogenesis protein 1101 3NIQS Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB U CELLULAR PROCESSES AND SIGNALING Intracellular trafficking, secretion, and vesicular transport ACIAD0363 CDS +1 356605 357402 no tpiA triosephosphate isomerase 512 3NJPP Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P) G METABOLISM Carbohydrate transport and metabolism ACIAD0364 CDS +1 357412 357741 no secG preprotein translocase IISP family, auxillary membrane component 186 3NNTJ Preprotein translocase SecG subunit U CELLULAR PROCESSES AND SIGNALING Intracellular trafficking, secretion, and vesicular transport ACIAD0367 CDS +3 358821 359345 no Putative ribosome maturation factor RimP 347 3NIWU Required for maturation of 30S ribosomal subunits S POORLY CHARACTERIZED Function unknown ACIAD0368 CDS +2 359381 360865 no nusA transcription termination/antitermination, L factor (N utilization substance protein A) 920 3NJKS Participates in both transcription termination and antitermination K INFORMATION STORAGE AND PROCESSING Transcription ACIAD0369 CDS +3 360876 363575 no infB protein chain initiation factor IF-2 1576 3NKI1 One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex J INFORMATION STORAGE AND PROCESSING Translation, ribosomal structure and biogenesis ACIAD0370 CDS +2 363575 363976 no rbfA ribosome-binding factor A 254 3NN3B One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA J INFORMATION STORAGE AND PROCESSING Translation, ribosomal structure and biogenesis ACIAD0371 CDS -1 364022 364438 no phaG pH adaptation potassium efflux system protein G 259 3NNNP Na+/H+ antiporter subunit P METABOLISM Inorganic ion transport and metabolism ACIAD0372 CDS -1 364448 364723 no phaF pH adaptation potassium efflux system protein F 169 3NP1Y Multiple resistance and pH regulation protein F (MrpF / PhaF) P METABOLISM Inorganic ion transport and metabolism ACIAD0373 CDS -2 364720 365247 no phaE pH adaptation potassium efflux system E transmembrane protein 348 3NMCI Na+/H+ ion antiporter subunit P METABOLISM Inorganic ion transport and metabolism ACIAD0374 CDS -3 365250 367058 no phaD pH adaptation potassium efflux system D transmembrane protein 1165 3NIJN Proton-conducting membrane transporter C METABOLISM Energy production and conversion ACIAD0374 CDS -3 365250 367058 no phaD pH adaptation potassium efflux system D transmembrane protein 1165 3NIJN Proton-conducting membrane transporter P METABOLISM Inorganic ion transport and metabolism ACIAD0375 CDS -1 367058 367408 no phaC pH adaptation potassium efflux system C transmembrane protein 212 3NNHT NADH-ubiquinone/plastoquinone oxidoreductase chain 4L P METABOLISM Inorganic ion transport and metabolism ACIAD0376 CDS -2 367423 370272 no phaAB pH adaptation potassium efflux system transmembrane protein 1814 3NIM9 Domain related to MnhB subunit of Na+/H+ antiporter C METABOLISM Energy production and conversion ACIAD0376 CDS -2 367423 370272 no phaAB pH adaptation potassium efflux system transmembrane protein 1814 3NIM9 Domain related to MnhB subunit of Na+/H+ antiporter P METABOLISM Inorganic ion transport and metabolism ACIAD0378 CDS -2 370600 371967 no conserved hypothetical protein; putative ATP binding site 885 3NJ2G AAA domain S POORLY CHARACTERIZED Function unknown ACIAD0379 CDS -2 371980 373482 no putative DNA helicase 1009 3NJ6N DNA helicase L INFORMATION STORAGE AND PROCESSING Replication, recombination and repair ACIAD0380 CDS -2 373492 374265 no hisIE bifunctional protein [Includes: phosphoribosyl-AMP cyclohydrolase; phosphoribosyl-ATP pyrophosphatase] 520 3NK5C belongs to the PRA-CH family E METABOLISM Amino acid transport and metabolism ACIAD0381 CDS -2 374434 375744 no putative oxidoreductase; putative flavoprotein monooxygenase 882 3NIMA FAD binding domain C METABOLISM Energy production and conversion ACIAD0381 CDS -2 374434 375744 no putative oxidoreductase; putative flavoprotein monooxygenase 882 3NIMA FAD binding domain H METABOLISM Coenzyme transport and metabolism ACIAD0382 CDS -1 375764 377383 no ubiB 2-octaprenylphenol hydroxylase of ubiquinone biosynthetic pathway 1041 3NJ93 ABC1 family S POORLY CHARACTERIZED Function unknown ACIAD0383 CDS -3 377397 378062 no ubiJ putative ubiquinone biosynthesis protein UbiJ 439 3NJZV ubiquinone biosynthetic process from chorismate S POORLY CHARACTERIZED Function unknown ACIAD0384 CDS -3 378075 379043 no ubiE S-adenosylmethionine : 2-DMK methyltransferase and 2-octaprenyl-6-methoxy-1,4-benzoquinone methylase 614 3NJ9G Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2) and the conversion of 2-polyprenyl-6-methoxy-1,4-benzoquinol (DDMQH2) to 2- polyprenyl-3-methyl-6-methoxy-1,4-benzoquinol (DMQH2) H METABOLISM Coenzyme transport and metabolism ACIAD0385 CDS -2 379177 379890 no conserved hypothetical protein 470 3NK2N S POORLY CHARACTERIZED Function unknown ACIAD0387 CDS +3 380877 381461 no acuA fimbrial protein AcuA 345 3NPU7 Fimbrial protein N CELLULAR PROCESSES AND SIGNALING Cell motility ACIAD0387 CDS +3 380877 381461 no acuA fimbrial protein AcuA 345 3NPU7 Fimbrial protein U CELLULAR PROCESSES AND SIGNALING Intracellular trafficking, secretion, and vesicular transport ACIAD0388 CDS +2 381485 382192 no acuD fimbrial chaperone AcuD 465 3NJE9 Pili assembly chaperone PapD, C-terminal domain M CELLULAR PROCESSES AND SIGNALING Cell wall/membrane/envelope biogenesis ACIAD0389 CDS +2 382220 384772 no acuC fimbrial usher AcuC 1662 3NM2C usher protein N CELLULAR PROCESSES AND SIGNALING Cell motility ACIAD0389 CDS +2 382220 384772 no acuC fimbrial usher AcuC 1662 3NM2C usher protein U CELLULAR PROCESSES AND SIGNALING Intracellular trafficking, secretion, and vesicular transport ACIAD0390 CDS +2 384773 385822 no acuG fimbrial protein AcuG 627 3NQC8 Fimbrial protein S POORLY CHARACTERIZED Function unknown ACIAD0394 CDS +3 386766 388190 no pap polyphosphate-AMP phosphotransferase 951 3NIMP Polyphosphate kinase 2 (PPK2) S POORLY CHARACTERIZED Function unknown ACIAD0395 CDS -2 388255 389574 no citA citrate-proton symporter (Citrate transporter) (Citrate carrier protein) (Citrate utilization determinant) (Citrate utilization protein A) 830 3NSX0 Sugar (and other) transporter E METABOLISM Amino acid transport and metabolism ACIAD0395 CDS -2 388255 389574 no citA citrate-proton symporter (Citrate transporter) (Citrate carrier protein) (Citrate utilization determinant) (Citrate utilization protein A) 830 3NSX0 Sugar (and other) transporter G METABOLISM Carbohydrate transport and metabolism ACIAD0395 CDS -2 388255 389574 no citA citrate-proton symporter (Citrate transporter) (Citrate carrier protein) (Citrate utilization determinant) (Citrate utilization protein A) 830 3NSX0 Sugar (and other) transporter P METABOLISM Inorganic ion transport and metabolism ACIAD0396 CDS -2 389764 390267 no conserved hypothetical protein 327 3NKKH protein domain associated with S POORLY CHARACTERIZED Function unknown ACIAD0397 CDS +3 390432 394097 no recC exonuclease V, gamma chain 2448 3NM1F A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit recognizes the wild- type Chi sequence, and when added to isolated RecB increases its ATP-dependent helicase processivity L INFORMATION STORAGE AND PROCESSING Replication, recombination and repair ACIAD0398 CDS +3 394104 397808 no recB exonuclease V, beta chain 2446 3NIUR A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit contributes ATPase, 3'-5' helicase, exonuclease activity and loads RecA onto ssDNA L INFORMATION STORAGE AND PROCESSING Replication, recombination and repair ACIAD0399 CDS +2 397904 399682 no recD exonuclease V, alpha subunit 1147 3NIKV A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD L INFORMATION STORAGE AND PROCESSING Replication, recombination and repair ACIAD0400 CDS -3 400224 401552 no ptative beta-lactamase-related domain-containing protein 887 3NIWT Beta-lactamase V CELLULAR PROCESSES AND SIGNALING Defense mechanisms ACIAD0401 CDS +3 401802 402071 no rpsO 30S ribosomal protein S15 177 3NNXP Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome J INFORMATION STORAGE AND PROCESSING Translation, ribosomal structure and biogenesis ACIAD0402 CDS +3 402324 404417 no pnp polyribonucleotide nucleotidyltransferase (Polynucleotide phosphorylase) (PNPase) 1308 3NIGW Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'-direction J INFORMATION STORAGE AND PROCESSING Translation, ribosomal structure and biogenesis ACIAD0403 CDS +1 404695 405990 no putative magnesium Mg(2+)/cobalt Co(2+) transport protein 831 3NIU4 CorA-like Mg2+ transporter protein P METABOLISM Inorganic ion transport and metabolism ACIAD0404 CDS +2 406178 406558 no crcB high-copy crc-csp restores normal chromosome condensation in presence of camphor or mukB mutations 247 3NP5A Important for reducing fluoride concentration in the cell, thus reducing its toxicity D CELLULAR PROCESSES AND SIGNALING Cell cycle control, cell division, chromosome partitioning ACIAD0405 CDS -2 406666 406989 no conserved hypothetical protein 218 3NPD2 MerR HTH family regulatory protein K INFORMATION STORAGE AND PROCESSING Transcription ACIAD0406 CDS -3 407001 407942 no cbpA curved DNA-binding protein, DnaJ homologue that functions as a co-chaperone of DnaK 617 3NIY8 DnaJ molecular chaperone homology domain O CELLULAR PROCESSES AND SIGNALING Posttranslational modification, protein turnover, chaperones ACIAD0407 CDS -2 408145 409032 no hslO heat shock protein Hsp33 550 3NIEJ Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress O CELLULAR PROCESSES AND SIGNALING Posttranslational modification, protein turnover, chaperones ACIAD0408 CDS -3 409071 410915 no kef glutathione-regulated potassium-efflux system protein (K(+)/H(+) antiporter) 1148 3NKJE Belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family P METABOLISM Inorganic ion transport and metabolism ACIAD0409 CDS -2 410989 413220 no priA primosomal protein N' (= factor Y) directs replication fork assembly at D-loops, ATP-dependent. 1491 3NJI2 Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA L INFORMATION STORAGE AND PROCESSING Replication, recombination and repair ACIAD0411 CDS +2 413360 414565 no xcpS general secretion pathway protein F 732 3NIVU general secretion pathway protein U CELLULAR PROCESSES AND SIGNALING Intracellular trafficking, secretion, and vesicular transport ACIAD0412 CDS +1 414571 415077 no xcpT general secretion pathway protein G 333 3NN5T general secretion pathway protein U CELLULAR PROCESSES AND SIGNALING Intracellular trafficking, secretion, and vesicular transport ACIAD0413 CDS +3 415341 415679 no conserved hypothetical protein; putative membrane protein 199 3NNSB S POORLY CHARACTERIZED Function unknown ACIAD0415 CDS -2 416095 417654 no lnt apolipoprotein N-acyltransferase, copper homeostasis protein 1055 3NIIR Transfers the fatty acyl group on membrane lipoproteins M CELLULAR PROCESSES AND SIGNALING Cell wall/membrane/envelope biogenesis ACIAD0416 CDS -3 417651 418490 no corC magnesium and cobalt efflux protein 546 3NIVB Transporter associated domain P METABOLISM Inorganic ion transport and metabolism ACIAD0417 CDS +3 418671 418934 no sirA small ubiquitous protein required for normal growth 181 3NNZ2 Belongs to the sulfur carrier protein TusA family O CELLULAR PROCESSES AND SIGNALING Posttranslational modification, protein turnover, chaperones ACIAD0418 CDS -1 419027 419815 no aroE dehydroshikimate reductase, NAD(P)-binding 522 3NJ6E Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA) E METABOLISM Amino acid transport and metabolism ACIAD0419 CDS -3 419892 420098 no yacG DNA gyrase inhibitor YacG 151 3NPSB Inhibits all the catalytic activities of DNA gyrase by preventing its interaction with DNA. Acts by binding directly to the C-terminal domain of GyrB, which probably disrupts DNA binding by the gyrase S POORLY CHARACTERIZED Function unknown ACIAD0420 CDS +1 420181 420819 no putative methyltransferase 435 3NJ05 Putative methyltransferase H METABOLISM Coenzyme transport and metabolism ACIAD0421 CDS +2 420809 422014 no putative flavoprotein 810 3NJ1T HI0933-like protein S POORLY CHARACTERIZED Function unknown ACIAD0422 CDS +3 422112 422507 no conserved hypothetical protein 285 3NT8N Glutathione-dependent formaldehyde-activating enzyme S POORLY CHARACTERIZED Function unknown ACIAD0424 CDS -2 422653 422985 no putative type III effector HopPmaJ 219 3NP33 HopJ type III effector protein S POORLY CHARACTERIZED Function unknown ACIAD0425 CDS -3 423252 423500 no rpmE2 50S ribosomal protein L31 type B 169 3NPDX Ribosomal protein L31 J INFORMATION STORAGE AND PROCESSING Translation, ribosomal structure and biogenesis ACIAD0426 CDS -2 423592 424923 no conserved hypothetical protein; putative ABC1 protein 863 3NIW4 ABC1 family S POORLY CHARACTERIZED Function unknown ACIAD0427 CDS +2 425141 426397 no putative acyl-CoA dehydrogenase 825 3NJK0 Acyl-CoA dehydrogenase, C-terminal domain I METABOLISM Lipid transport and metabolism ACIAD0428 CDS +2 426437 427687 no putative acyl-CoA dehydrogenase 811 3NKAZ Acyl-CoA dehydrogenase, C-terminal domain I METABOLISM Lipid transport and metabolism ACIAD0429 CDS -2 427750 429099 no norM multidrug resistance protein (Na(+)/drug antiporter) (Multidrug- efflux transporter) 854 3NK44 MatE V CELLULAR PROCESSES AND SIGNALING Defense mechanisms ACIAD0431 CDS -1 429128 429589 no putative transporter 298 3NN65 Putative inner membrane exporter, YdcZ S POORLY CHARACTERIZED Function unknown ACIAD0432 CDS +3 429708 430865 no putative heme chaperone HemW like 779 3NIS7 Involved in the biosynthesis of porphyrin-containing compound H METABOLISM Coenzyme transport and metabolism ACIAD0433 CDS -3 430989 431744 no putative short-chain dehydrogenase 495 3NJ6Y KR domain I METABOLISM Lipid transport and metabolism ACIAD0433 CDS -3 430989 431744 no putative short-chain dehydrogenase 495 3NJ6Y KR domain Q METABOLISM Secondary metabolites biosynthesis, transport and catabolism ACIAD0434 CDS +1 431869 432768 no putative transcriptional regulator (LysR family) 597 3NK52 LysR substrate binding domain K INFORMATION STORAGE AND PROCESSING Transcription ACIAD0436 CDS -1 432824 433387 no ahpC alkyl hydroperoxide reductase, C22 subunit, thioredoxin-like, detoxification of hydroperoxides 385 3NIQ5 Alkyl hydroperoxide reductase O CELLULAR PROCESSES AND SIGNALING Posttranslational modification, protein turnover, chaperones ACIAD0437 CDS -2 433978 435825 no putative very-long-chain acyl-CoA synthetase 1248 3NKGQ AMP-binding enzyme C-terminal domain I METABOLISM Lipid transport and metabolism ACIAD0437 CDS -2 433978 435825 no putative very-long-chain acyl-CoA synthetase 1248 3NKGQ AMP-binding enzyme C-terminal domain Q METABOLISM Secondary metabolites biosynthesis, transport and catabolism ACIAD0438 CDS -2 436009 439425 no rne ribonuclease E (RNase E): endoribonuclease for rRNA processing and mRNA degradation 1900 3NJRE Endoribonuclease that plays a central role in RNA processing and decay. Required for the maturation of 5S and 16S rRNAs and the majority of tRNAs. Also involved in the degradation of most mRNAs J INFORMATION STORAGE AND PROCESSING Translation, ribosomal structure and biogenesis ACIAD0441 CDS +3 439737 439982 no hypothetical protein 73.6 3NNPB S POORLY CHARACTERIZED Function unknown ACIAD0442 CDS +3 440160 441092 no rluC 23S rRNA pseudouridylate synthase 597 3NJU3 Responsible for synthesis of pseudouridine from uracil J INFORMATION STORAGE AND PROCESSING Translation, ribosomal structure and biogenesis ACIAD0443 CDS +2 441089 441754 no putative phosphoglycolate phosphatase protein 439 3NJR7 HAD-hyrolase-like S POORLY CHARACTERIZED Function unknown ACIAD0444 CDS +3 441801 442529 no putative transcriptional regulator 483 3NMAS WYL domain K INFORMATION STORAGE AND PROCESSING Transcription ACIAD0445 CDS +3 442581 443186 no putative glutathione S-transferase 414 3NKA7 Glutathione S-transferase, N-terminal domain O CELLULAR PROCESSES AND SIGNALING Posttranslational modification, protein turnover, chaperones ACIAD0446 CDS -2 443233 443907 no membrane protein of unknown function DUF1345 432 3NM3Q Protein of unknown function (DUF1345) S POORLY CHARACTERIZED Function unknown ACIAD0448 CDS -2 444028 444924 no putative transcriptional regulator (LysR family) 583 3NKV9 LysR substrate binding domain K INFORMATION STORAGE AND PROCESSING Transcription ACIAD0449 CDS +3 445278 446255 no putative cation transport protein 609 3NIX1 Cation efflux family P METABOLISM Inorganic ion transport and metabolism ACIAD0450 CDS +1 446311 447363 no putative metallo lactamase B domain containing protein 749 3NKCP Beta-lactamase superfamily domain S POORLY CHARACTERIZED Function unknown ACIAD0451 CDS -1 447419 448939 no katA catalase (hydroperoxidase II) 1060 3NJBI serves to protect cells from the toxic effects of hydrogen peroxide C METABOLISM Energy production and conversion ACIAD0452 CDS +1 449533 451179 no putative acyl-CoA dehydrogenase (AidB) 1107 3NM6N Acyl-CoA dehydrogenase, C-terminal domain I METABOLISM Lipid transport and metabolism ACIAD0454 CDS -3 451233 453527 no ptsP phosphoenolpyruvate-protein phosphotransferase 1456 3NIHN Belongs to the PEP-utilizing enzyme family T CELLULAR PROCESSES AND SIGNALING Signal transduction mechanisms ACIAD0455 CDS -2 453598 454098 no nudH (di)nucleoside polyphosphate hydrolase (Ap5A pyrophosphatase) 356 3NIK9 Accelerates the degradation of transcripts by removing pyrophosphate from the 5'-end of triphosphorylated RNA, leading to a more labile monophosphorylated state that can stimulate subsequent ribonuclease cleavage L INFORMATION STORAGE AND PROCESSING Replication, recombination and repair ACIAD0456 CDS +2 454283 454933 no hisK histidinol-phosphatase 451 3NITK haloacid dehalogenase-like hydrolase E METABOLISM Amino acid transport and metabolism ACIAD0457 CDS -2 454936 455865 no putative transcriptional regulator (LysR family) 596 3NJKP LysR substrate binding domain K INFORMATION STORAGE AND PROCESSING Transcription ACIAD0459 CDS +3 456045 457100 no putative vanillate O-demethylase oxygenase subunit 726 3NKKA Rieske [2Fe-2S] domain P METABOLISM Inorganic ion transport and metabolism ACIAD0460 CDS -2 457207 459327 no conserved hypothetical protein 1475 1RQI4 methyltransferase Q METABOLISM Secondary metabolites biosynthesis, transport and catabolism ACIAD0461 CDS -2 459565 460446 no putative transcriptional regulator (LysR family) 587 3NJPX Transcriptional regulator K INFORMATION STORAGE AND PROCESSING Transcription ACIAD0462 CDS -1 460541 460810 no conserved hypothetical protein 175 3NPBA Predicted membrane protein (DUF2061) S POORLY CHARACTERIZED Function unknown ACIAD0463 CDS +2 461051 462484 no leuC 3-isopropylmalate dehydratase (isomerase), subunit with LeuD 954 3NJM4 Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate E METABOLISM Amino acid transport and metabolism ACIAD0465 CDS +1 462484 463137 no putative glutathione S-transferase 441 3NKXU Glutathione S-transferase, N-terminal domain O CELLULAR PROCESSES AND SIGNALING Posttranslational modification, protein turnover, chaperones ACIAD0466 CDS +1 463156 463806 no leuD 3-isopropylmalate isomerase (dehydratase), subunit with LeuC 448 3NK10 Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate E METABOLISM Amino acid transport and metabolism ACIAD0468 CDS +3 463917 464489 no conserved hypothetical protein 383 3NKSV S POORLY CHARACTERIZED Function unknown ACIAD0469 CDS +3 464538 465617 no leuB 3-isopropylmalate dehydrogenase 691 3NK2W Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate C METABOLISM Energy production and conversion ACIAD0469 CDS +3 464538 465617 no leuB 3-isopropylmalate dehydrogenase 691 3NK2W Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate E METABOLISM Amino acid transport and metabolism ACIAD0471 CDS +1 465820 466197 no conserved hypothetical protein 242 3NNJ5 Lysozyme inhibitor LprI S POORLY CHARACTERIZED Function unknown ACIAD0472 CDS -1 466295 466516 no infA protein chain initiation factor IF-1 148 3NPBC One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex J INFORMATION STORAGE AND PROCESSING Translation, ribosomal structure and biogenesis ACIAD0473 CDS +2 466745 467752 no putative transcriptional regulator (AraC family) 659 3NJRU Arabinose-binding domain of AraC transcription regulator, N-term K INFORMATION STORAGE AND PROCESSING Transcription ACIAD0474 CDS -1 467810 468625 no truA tRNA-pseudouridine synthase I 565 3NJS9 Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs J INFORMATION STORAGE AND PROCESSING Translation, ribosomal structure and biogenesis ACIAD0476 CDS -1 468644 469609 no putative L-asparaginase I (AnsA) 640 3NJPT Asparaginase E METABOLISM Amino acid transport and metabolism ACIAD0476 CDS -1 468644 469609 no putative L-asparaginase I (AnsA) 640 3NJPT Asparaginase J INFORMATION STORAGE AND PROCESSING Translation, ribosomal structure and biogenesis ACIAD0477 CDS -2 469657 470811 no FimV FimV domain-containing protein 656 3NKTD S POORLY CHARACTERIZED Function unknown ACIAD0479 CDS -2 471037 472155 no asd aspartate-semialdehyde dehydrogenase, NAD(P)-binding 751 3NJ2Q Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate E METABOLISM Amino acid transport and metabolism ACIAD0480 CDS +1 472336 473457 no conserved hypothetical protein; putative membrane protein 717 3NK9Y Endonuclease/Exonuclease/phosphatase family S POORLY CHARACTERIZED Function unknown ACIAD0481 CDS +2 474293 475597 no gltP glutamate:aspartate symport protein (DAACS family) 791 3NJTM Catalyzes the proton-dependent transport of glutamate and aspartate U CELLULAR PROCESSES AND SIGNALING Intracellular trafficking, secretion, and vesicular transport ACIAD0482 CDS -2 475660 476766 no putative glycosyltransferase 741 3NJCZ Glycosyl transferase 4-like domain M CELLULAR PROCESSES AND SIGNALING Cell wall/membrane/envelope biogenesis ACIAD0484 CDS -3 477033 477968 no lpxP Lipid A biosynthesis (KDO) 2-(lauroyl)-lipid IVA acyltransferase (Heat shock protein B) 654 3NJM6 Catalyzes the transfer of laurate from lauroyl-acyl carrier protein (ACP) to Kdo(2)-lipid IV(A) to form Kdo(2)- (lauroyl)-lipid IV(A) M CELLULAR PROCESSES AND SIGNALING Cell wall/membrane/envelope biogenesis ACIAD0485 CDS -3 478191 479873 no putative gamma-glutamyltranspeptidase 1118 3NIUX Gamma-glutamyltranspeptidase M CELLULAR PROCESSES AND SIGNALING Cell wall/membrane/envelope biogenesis ACIAD0486 CDS -3 480159 480791 no putative transporter protein 390 3NT7H LysE type translocator E METABOLISM Amino acid transport and metabolism ACIAD0487 CDS -2 481015 482931 no uup transport protein Uup (ABC superfamily, atp_bind) 1209 3NIM1 COG0488 ATPase components of ABC transporters with duplicated ATPase domains S POORLY CHARACTERIZED Function unknown ACIAD0488 CDS +2 482954 483199 no conserved hypothetical protein; putative SlyX protein 159 3NPAA SlyX S POORLY CHARACTERIZED Function unknown ACIAD0489 CDS +1 483253 484257 no conserved hypothetical protein 647 3NKD4 S POORLY CHARACTERIZED Function unknown ACIAD0492 CDS +3 484428 484892 no conserved hypothetical protein 306 3NN3T S POORLY CHARACTERIZED Function unknown ACIAD0493 CDS +3 484929 487574 no topA DNA topoisomerase type I, omega protein 1746 3NJWY Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone L INFORMATION STORAGE AND PROCESSING Replication, recombination and repair ACIAD0494 CDS +1 487795 488367 no conserved hypothetical protein; putative membrane protein 354 3NIHS Short repeat of unknown function (DUF308) S POORLY CHARACTERIZED Function unknown ACIAD0495 CDS +1 488419 490437 no putative ATP-dependent DNA helicase (PcrA) 1339 3NKBE UvrD-like helicase C-terminal domain L INFORMATION STORAGE AND PROCESSING Replication, recombination and repair ACIAD0496 CDS +2 490496 490756 no putative RNA-binding protein 167 3NPDV RNA recognition motif S POORLY CHARACTERIZED Function unknown ACIAD0497 CDS +3 490749 491120 no conserved hypothetical protein 259 3NNXT ASCH domain S POORLY CHARACTERIZED Function unknown ACIAD0498 CDS +1 491239 491742 no conserved hypothetical protein 329 3NKG9 S POORLY CHARACTERIZED Function unknown ACIAD0499 CDS +2 491855 492133 no conserved hypothetical protein 169 3NNX8 S POORLY CHARACTERIZED Function unknown ACIAD0500 CDS -3 492195 493913 no putative transport protein (CPA2 family ) 1053 3NJCB Belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family P METABOLISM Inorganic ion transport and metabolism ACIAD0501 CDS -1 494054 494209 no rpmG 50S ribosomal protein L33 102 3NPRW Belongs to the bacterial ribosomal protein bL33 family J INFORMATION STORAGE AND PROCESSING Translation, ribosomal structure and biogenesis ACIAD0502 CDS -1 494222 494458 no rpmB 50S ribosomal protein L28 153 3NNZ1 Belongs to the bacterial ribosomal protein bL28 family J INFORMATION STORAGE AND PROCESSING Translation, ribosomal structure and biogenesis ACIAD0503 CDS -3 494625 496073 no calB coniferyl aldehyde dehydrogenase (CALDH) 978 3NJP9 belongs to the aldehyde dehydrogenase family C METABOLISM Energy production and conversion ACIAD0504 CDS +2 496193 496882 no putative transcriptional regulator (TetR-family) 454 3NIMF Bacterial transcriptional repressor K INFORMATION STORAGE AND PROCESSING Transcription ACIAD0505 CDS +2 496943 497833 no purU1 formyltetrahydrofolate deformylase 590 3NKD9 Catalyzes the hydrolysis of 10-formyltetrahydrofolate (formyl-FH4) to formate and tetrahydrofolate (FH4) F METABOLISM Nucleotide transport and metabolism ACIAD0507 CDS +2 498143 498925 no putative TonB 389 3NM4S Gram-negative bacterial TonB protein C-terminal M CELLULAR PROCESSES AND SIGNALING Cell wall/membrane/envelope biogenesis ACIAD0508 CDS +3 498945 499568 no putative biopolymer transport protein (ExbB) 384 3NJB7 MotA TolQ ExbB proton channel U CELLULAR PROCESSES AND SIGNALING Intracellular trafficking, secretion, and vesicular transport ACIAD0509 CDS +2 499568 499972 no putative biopolymer transport protein (ExbD) 249 3NN37 Biopolymer transport protein U CELLULAR PROCESSES AND SIGNALING Intracellular trafficking, secretion, and vesicular transport ACIAD0510 CDS -2 500029 500562 no msrA peptide methionine sulfoxide reductase (Protein- methionine-S-oxide reductase) (Peptide Met(O) reductase) 365 3NJHY Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine O CELLULAR PROCESSES AND SIGNALING Posttranslational modification, protein turnover, chaperones ACIAD0511 CDS -3 500649 500996 no conserved hypothetical protein; putative heat shock protein HslJ 231 3NTI2 META domain O CELLULAR PROCESSES AND SIGNALING Posttranslational modification, protein turnover, chaperones ACIAD0513 CDS -3 501300 502358 no conserved hypothetical protein; putative membrane protein 714 3NJ5I Domain of unknown function (DUF4105) S POORLY CHARACTERIZED Function unknown ACIAD0514 CDS -1 502385 502894 no folA dihydrofolate reductase 346 3NJ26 Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis H METABOLISM Coenzyme transport and metabolism ACIAD0515 CDS -1 502907 503749 no thyA thymidylate synthase (TS) (TSase) 593 3NKAC Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis F METABOLISM Nucleotide transport and metabolism ACIAD0516 CDS -2 503860 504156 no conserved hypothetical protein; putative membrane protein 150 3NPE5 S POORLY CHARACTERIZED Function unknown ACIAD0517 CDS -1 504221 504646 no conserved hypothetical protein; putative membrane protein 276 3NP0G S POORLY CHARACTERIZED Function unknown ACIAD0518 CDS -3 504762 505583 no lgt prolipoprotein diacylglyceryl transferase 592 3NJV6 Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins M CELLULAR PROCESSES AND SIGNALING Cell wall/membrane/envelope biogenesis ACIAD0519 CDS +2 505676 506452 no conserved hypothetical protein 530 3NKP8 Transport and Golgi organisation 2 S POORLY CHARACTERIZED Function unknown ACIAD0520 CDS -1 506501 508486 no putative phosphatase; putative alkaline phosphatase 1321 3NJT7 Bacterial protein of unknown function (DUF839) S POORLY CHARACTERIZED Function unknown ACIAD0521 CDS -1 508664 509425 no tatC Sec-independent protein translocase protein 481 3NIT5 Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. Together with TatB, TatC is part of a receptor directly interacting with Tat signal peptides U CELLULAR PROCESSES AND SIGNALING Intracellular trafficking, secretion, and vesicular transport ACIAD0522 CDS -2 509422 509880 no tatB Sec-independent protein translocase protein 293 3NPHJ Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. Together with TatC, TatB is part of a receptor directly interacting with Tat signal peptides. TatB may form an oligomeric binding site that transiently accommodates folded Tat precursor proteins before their translocation U CELLULAR PROCESSES AND SIGNALING Intracellular trafficking, secretion, and vesicular transport ACIAD0523 CDS -2 509893 510129 no tatA Sec-independent protein translocase protein 145 3NPBJ Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system U CELLULAR PROCESSES AND SIGNALING Intracellular trafficking, secretion, and vesicular transport ACIAD0524 CDS +2 510266 511144 no putative permease 569 3NSQE Auxin Efflux Carrier S POORLY CHARACTERIZED Function unknown ACIAD0526 CDS -3 511425 512096 no putative protein controls HAP (6-N-hydroxylaminopurine) mutagenesis (Ham1) 445 3NJHQ Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions F METABOLISM Nucleotide transport and metabolism ACIAD0527 CDS -2 512131 512718 no conserved hypothetical protein; putative tetratricopeptide repeat family protein 271 3NKVU Sel1-like repeats. S POORLY CHARACTERIZED Function unknown ACIAD0528 CDS -3 512715 513311 no metW methionine biosynthesis protein 396 3NKFT Methionine biosynthesis protein MetW Q METABOLISM Secondary metabolites biosynthesis, transport and catabolism ACIAD0529 CDS -1 513308 514471 no metXS Homoserine O-succinyltransferase 763 3NK6R Transfers a succinyl group from succinyl-CoA to L- homoserine, forming succinyl-L-homoserine E METABOLISM Amino acid transport and metabolism ACIAD0530 CDS -3 514557 516254 no leuA 2-isopropylmalate synthase (Alpha-isopropylmalate synthase) (Alpha-IPM synthetase) 1130 3NJF8 Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate) E METABOLISM Amino acid transport and metabolism ACIAD0531 CDS -3 516705 517388 no piuC iron-uptake factor 466 3NJ5Z monosaccharide binding S POORLY CHARACTERIZED Function unknown ACIAD0532 CDS -3 517500 519722 no putative ferric siderophore receptor protein 1452 3NJSR TonB dependent receptor P METABOLISM Inorganic ion transport and metabolism ACIAD0533 CDS +3 520056 521390 no tig trigger factor, molecular chaperone involved in septum formation 820 3NIKK Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase D CELLULAR PROCESSES AND SIGNALING Cell cycle control, cell division, chromosome partitioning ACIAD0534 CDS +3 521583 522188 no clpP ATP-dependent Clp protease proteolytic subunit (Endopeptidase Clp) (Caseinolytic protease) (Protease Ti) (Heat shock protein F21.5) 398 3NIST Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins O CELLULAR PROCESSES AND SIGNALING Posttranslational modification, protein turnover, chaperones ACIAD0534 CDS +3 521583 522188 no clpP ATP-dependent Clp protease proteolytic subunit (Endopeptidase Clp) (Caseinolytic protease) (Protease Ti) (Heat shock protein F21.5) 398 3NIST Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins U CELLULAR PROCESSES AND SIGNALING Intracellular trafficking, secretion, and vesicular transport ACIAD0535 CDS +1 522217 523527 no clpX ATP-dependent Clp protease ATP-binding subunit 845 3NISF ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP O CELLULAR PROCESSES AND SIGNALING Posttranslational modification, protein turnover, chaperones ACIAD0536 CDS +3 523674 524387 no conserved hypothetical protein; putative signal peptide 495 3NIFM Protein of unknown function (DUF2846) S POORLY CHARACTERIZED Function unknown ACIAD0537 CDS -3 524448 525011 no conserved hypothetical protein; putative signal peptide 344 3NMTI Uncharacterized protein conserved in bacteria (DUF2059) S POORLY CHARACTERIZED Function unknown ACIAD0538 CDS -3 525159 526685 no fumA fumarate hydratase 964 3NJSC Catalyzes the reversible hydration of fumarate to (S)- malate C METABOLISM Energy production and conversion ACIAD0539 CDS +2 526841 527455 no putative methyltransferase 424 3NTMF Methyltransferase domain Q METABOLISM Secondary metabolites biosynthesis, transport and catabolism ACIAD0540 CDS -2 527524 529686 no pta phosphate acetyltransferase 1384 3NJD4 belongs to the CobB CobQ family C METABOLISM Energy production and conversion ACIAD0541 CDS -1 529730 530935 no ack acetate kinase (propionate kinase) 795 3NJ9F Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction H METABOLISM Coenzyme transport and metabolism ACIAD0542 CDS +1 532423 534270 no edd phosphogluconate dehydratase (6-phosphogluconate dehydratase) 1208 3NKHE Belongs to the IlvD Edd family E METABOLISM Amino acid transport and metabolism ACIAD0542 CDS +1 532423 534270 no edd phosphogluconate dehydratase (6-phosphogluconate dehydratase) 1208 3NKHE Belongs to the IlvD Edd family G METABOLISM Carbohydrate transport and metabolism ACIAD0543 CDS +1 534304 534933 no eda 4-hydroxy-2-oxoglutarate aldolase / 2-dehydro-3-deoxy-phosphogluconate aldolase 412 3NMUZ KDPG and KHG aldolase G METABOLISM Carbohydrate transport and metabolism ACIAD0544 CDS +2 535118 536455 no gntT high-affinity gluconate permease (GntP family) 822 3NJAN GntP family permease E METABOLISM Amino acid transport and metabolism ACIAD0544 CDS +2 535118 536455 no gntT high-affinity gluconate permease (GntP family) 822 3NJAN GntP family permease G METABOLISM Carbohydrate transport and metabolism ACIAD0545 CDS +3 536472 536984 no gntK thermoresistant gluconokinase (Gluconate kinase) 335 3NMP4 AAA domain F METABOLISM Nucleotide transport and metabolism ACIAD0546 CDS +2 537122 538762 no putative NADP-dependent glyceraldehyde-3-phosphate dehydrogenase 1097 3NM7B Aldehyde dehydrogenase family C METABOLISM Energy production and conversion ACIAD0547 CDS -2 538888 540153 no proA gamma-glutamyl phosphate reductase (GPR) (Glutamate-5- semialdehyde dehydrogenase) (Glutamyl-gamma-semialdehyde dehydrogenase) (GSA dehydrogenase) 813 3NJAC Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate E METABOLISM Amino acid transport and metabolism ACIAD0549 CDS +2 540446 541780 no putative hydrolase 875 3NJ6I alpha/beta hydrolase fold S POORLY CHARACTERIZED Function unknown ACIAD0550 CDS -2 541810 542655 no conserved hypothetical protein 573 3NKN2 Leucine carboxyl methyltransferase Q METABOLISM Secondary metabolites biosynthesis, transport and catabolism ACIAD0551 CDS -3 542775 543794 no nagZ beta-N-acetyl-D-glucosaminidase 673 3NKCV Plays a role in peptidoglycan recycling by cleaving the terminal beta-1,4-linked N-acetylglucosamine (GlcNAc) from peptide-linked peptidoglycan fragments, giving rise to free GlcNAc, anhydro-N-acetylmuramic acid and anhydro-N-acetylmuramic acid-linked peptides G METABOLISM Carbohydrate transport and metabolism ACIAD0552 CDS +2 544031 546214 no prc carboxy-terminal protease for penicillin-binding protein 1330 3NK7I Belongs to the peptidase S41A family M CELLULAR PROCESSES AND SIGNALING Cell wall/membrane/envelope biogenesis ACIAD0553 CDS +1 546397 547686 no putative glycosyl transferase 873 3NJVX Glycosyltransferase Family 4 M CELLULAR PROCESSES AND SIGNALING Cell wall/membrane/envelope biogenesis ACIAD0554 CDS +2 547718 548272 no putative phosphatidylglycerophosphatase B (PgpB) 362 3NJTU Acid phosphatase homologues I METABOLISM Lipid transport and metabolism ACIAD0555 CDS +1 548326 548544 no putative protein believed to be involved in assembly of Fe-S clusters 154 3NPEH Fe-S assembly protein IscX S POORLY CHARACTERIZED Function unknown ACIAD0556 CDS +3 548655 549086 no ndk nucleoside diphosphate kinase (NDK) (NDP kinase) (Nucleoside-2-P kinase) 276 3NK6T Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate F METABOLISM Nucleotide transport and metabolism ACIAD0557 CDS +2 549209 550453 no rlmN 23S rRNA adenosine methyltransferase 810 3NJI9 Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs J INFORMATION STORAGE AND PROCESSING Translation, ribosomal structure and biogenesis ACIAD0558 CDS +2 550472 551272 no pilF type 4 fimbrial biogenesis protein 525 3NT5Q Tetratricopeptide repeat N CELLULAR PROCESSES AND SIGNALING Cell motility ACIAD0558 CDS +2 550472 551272 no pilF type 4 fimbrial biogenesis protein 525 3NT5Q Tetratricopeptide repeat U CELLULAR PROCESSES AND SIGNALING Intracellular trafficking, secretion, and vesicular transport ACIAD0560 CDS +1 551263 552045 no conserved hypothetical protein 494 3NJYT Domain of unknown function (DUF4115) S POORLY CHARACTERIZED Function unknown ACIAD0561 CDS +3 552069 553184 no ispG 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate synthase 714 3NIWR Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate I METABOLISM Lipid transport and metabolism ACIAD0562 CDS +2 553181 554473 no hisS histidyl-tRNA synthetase 840 3NKTF histidyl-tRNA synthetase J INFORMATION STORAGE AND PROCESSING Translation, ribosomal structure and biogenesis ACIAD0563 CDS +3 554505 555206 no conserved hypothetical protein 431 3NJGH Tetratricopeptide repeat-like domain S POORLY CHARACTERIZED Function unknown ACIAD0564 CDS +2 555206 556360 no conserved hypothetical protein; putative PQQ enzyme repeat domain protein 755 3NIR2 Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane M CELLULAR PROCESSES AND SIGNALING Cell wall/membrane/envelope biogenesis ACIAD0565 CDS +1 556522 557958 no putative GTP-binding protein EngA 931 3NJ82 GTPase that plays an essential role in the late steps of ribosome biogenesis S POORLY CHARACTERIZED Function unknown ACIAD0566 CDS +3 558138 558755 no conserved hypothetical protein 402 3NKQK Beta-ketoacyl synthase, N-terminal domain I METABOLISM Lipid transport and metabolism ACIAD0566 CDS +3 558138 558755 no conserved hypothetical protein 402 3NKQK Beta-ketoacyl synthase, N-terminal domain Q METABOLISM Secondary metabolites biosynthesis, transport and catabolism ACIAD0567 CDS +2 558743 559540 no putative acyltransferase 525 3NJI1 Phosphate acyltransferases I METABOLISM Lipid transport and metabolism ACIAD0568 CDS +1 559537 559797 no putative acyl carrier protein 161 3NPA4 Phosphopantetheine attachment site I METABOLISM Lipid transport and metabolism ACIAD0568 CDS +1 559537 559797 no putative acyl carrier protein 161 3NPA4 Phosphopantetheine attachment site Q METABOLISM Secondary metabolites biosynthesis, transport and catabolism ACIAD0569 CDS +1 559807 560052 no putative acyl carrier protein (ACP) 155 3NPBS Carrier of the growing fatty acid chain in fatty acid biosynthesis I METABOLISM Lipid transport and metabolism ACIAD0569 CDS +1 559807 560052 no putative acyl carrier protein (ACP) 155 3NPBS Carrier of the growing fatty acid chain in fatty acid biosynthesis Q METABOLISM Secondary metabolites biosynthesis, transport and catabolism ACIAD0570 CDS +3 560052 560618 no conserved hypothetical protein; putative membrane protein 385 3NN3P Intracellular septation protein A S POORLY CHARACTERIZED Function unknown ACIAD0571 CDS +1 560611 562278 no conserved hypothetical protein 1114 3NKFC AMP-binding enzyme I METABOLISM Lipid transport and metabolism ACIAD0571 CDS +1 560611 562278 no conserved hypothetical protein 1114 3NKFC AMP-binding enzyme Q METABOLISM Secondary metabolites biosynthesis, transport and catabolism ACIAD0572 CDS +3 562275 563012 no putative glycosyl transferase (GT2 family) 512 3NM7H Glycosyl transferase family 2 M CELLULAR PROCESSES AND SIGNALING Cell wall/membrane/envelope biogenesis ACIAD0573 CDS +2 563015 563938 no putative bacterial lipid A biosynthesis acyltransferase family 625 3NM8U Bacterial lipid A biosynthesis acyltransferase S POORLY CHARACTERIZED Function unknown ACIAD0574 CDS +3 563940 565523 no hutH histidine ammonia-lyase protein (Histidase) 1026 3NJM0 histidine ammonia-lyase activity E METABOLISM Amino acid transport and metabolism ACIAD0575 CDS +1 565513 565953 no conserved hypothetical protein 306 3NN6B Thioesterase-like superfamily S POORLY CHARACTERIZED Function unknown ACIAD0576 CDS +3 566019 566606 no conserved hypothetical protein 369 3NIJE Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane) M CELLULAR PROCESSES AND SIGNALING Cell wall/membrane/envelope biogenesis ACIAD0577 CDS +1 566608 568905 no conserved hypothetical protein; putative membrane protein 1464 3NJWN exporter S POORLY CHARACTERIZED Function unknown ACIAD0578 CDS +1 568921 570237 no putative oxidoreductase protein; putative dehydrogenase (flavoprotein) 880 3NKZH Tryptophan halogenase C METABOLISM Energy production and conversion ACIAD0579 CDS +2 570239 570781 no conserved hypothetical protein 348 3NMIJ Protein of unknown function (DUF3261) S POORLY CHARACTERIZED Function unknown ACIAD0580 CDS +2 570788 572038 no putative 3-oxoacyl-[acyl-carrier-protein] synthase (Beta-ketoacyl-ACP synthase) 809 3NIH4 Beta-ketoacyl synthase, C-terminal domain I METABOLISM Lipid transport and metabolism ACIAD0580 CDS +2 570788 572038 no putative 3-oxoacyl-[acyl-carrier-protein] synthase (Beta-ketoacyl-ACP synthase) 809 3NIH4 Beta-ketoacyl synthase, C-terminal domain Q METABOLISM Secondary metabolites biosynthesis, transport and catabolism ACIAD0581 CDS +1 572035 572478 no conserved hypothetical protein; putative 3-hydroxylacyl-(acyl carrier protein) dehydratase 296 3NNI1 3-hydroxylacyl-(Acyl carrier protein) dehydratase I METABOLISM Lipid transport and metabolism ACIAD0582 CDS +3 572475 573200 no fabG 3-oxoacyl-[acyl-carrier protein] reductase (3-ketoacyl- acyl carrier protein reductase) 461 3NIWM KR domain I METABOLISM Lipid transport and metabolism ACIAD0582 CDS +3 572475 573200 no fabG 3-oxoacyl-[acyl-carrier protein] reductase (3-ketoacyl- acyl carrier protein reductase) 461 3NIWM KR domain Q METABOLISM Secondary metabolites biosynthesis, transport and catabolism ACIAD0583 CDS +2 573200 574423 no fabF 3-oxoacyl-[acyl-carrier-protein] synthase II 802 3NIQ4 Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP I METABOLISM Lipid transport and metabolism ACIAD0584 CDS +3 574437 574871 no conserved hypothetical protein 279 3NNGB excinuclease, ATPase subunit S POORLY CHARACTERIZED Function unknown ACIAD0585 CDS +3 574893 575549 no putative holo-(acyl carrier protein) synthase 2 (AcpT) (phophopantetheinyltransferase) 446 3NJX1 Belongs to the P-Pant transferase superfamily H METABOLISM Coenzyme transport and metabolism ACIAD0586 CDS +2 575585 575857 no hypothetical protein; putative membrane protein 167 3NQ73 S POORLY CHARACTERIZED Function unknown ACIAD0587 CDS -1 575921 576889 no secF preprotein translocase, IISP family, membrane subunit 586 3NKZC Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA U CELLULAR PROCESSES AND SIGNALING Intracellular trafficking, secretion, and vesicular transport ACIAD0588 CDS -2 576898 578799 no secD preprotein translocase, IISP family, part of the channel 1189 3NJM1 Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA U CELLULAR PROCESSES AND SIGNALING Intracellular trafficking, secretion, and vesicular transport ACIAD0589 CDS -2 578854 579183 no putative SecYEG protein translocase auxillary subunit (YajC) 208 3NNII Preprotein translocase subunit YajC U CELLULAR PROCESSES AND SIGNALING Intracellular trafficking, secretion, and vesicular transport ACIAD0590 CDS -2 579286 580446 no tgt queuine tRNA-ribosyltransferase (tRNA-guanine transglycosylase) (Guanine insertion enzyme) 795 3NK2U Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the product. After dissociation, two additional enzymatic reactions on the tRNA convert PreQ1 to queuine (Q), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2- cyclopenten-1-yl)amino)methyl)-7-deazaguanosine) F METABOLISM Nucleotide transport and metabolism ACIAD0591 CDS -2 580735 581769 no queA S-adenosylmethionine:tRNA ribosyltransferase-isomerase (Queuosine biosynthesis protein ) 686 3NKA4 Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA) J INFORMATION STORAGE AND PROCESSING Translation, ribosomal structure and biogenesis ACIAD0593 CDS +1 582628 582846 no conserved hypothetical protein 134 3NQ9K S POORLY CHARACTERIZED Function unknown ACIAD0595 CDS +3 583098 584363 no putative sensory transduction histidine kinase 818 3NJ7V His Kinase A (phosphoacceptor) domain T CELLULAR PROCESSES AND SIGNALING Signal transduction mechanisms ACIAD0596 CDS +1 584401 587175 no glnE glutamine synthetase adenylyltransferase 1790 3NJBF Involved in the regulation of glutamine synthetase GlnA, a key enzyme in the process to assimilate ammonia. When cellular nitrogen levels are high, the C-terminal adenylyl transferase (AT) inactivates GlnA by covalent transfer of an adenylyl group from ATP to specific tyrosine residue of GlnA, thus reducing its activity. Conversely, when nitrogen levels are low, the N-terminal adenylyl removase (AR) activates GlnA by removing the adenylyl group by phosphorolysis, increasing its activity. The regulatory region of GlnE binds the signal transduction protein PII (GlnB) which indicates the nitrogen status of the cell H METABOLISM Coenzyme transport and metabolism ACIAD0597 CDS +3 587193 588128 no ilvE branched-chain amino acid transferase 635 3NK5G Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family E METABOLISM Amino acid transport and metabolism ACIAD0598 CDS +1 588175 589083 no conserved hypothetical protein 605 3NM2D Mitochondrial fission ELM1 M CELLULAR PROCESSES AND SIGNALING Cell wall/membrane/envelope biogenesis ACIAD0599 CDS +2 589088 590116 no conserved hypothetical protein 701 3NKBK Glycosyl transferases group 1 S POORLY CHARACTERIZED Function unknown ACIAD0600 CDS +1 590113 590868 no putative polysaccharide deacetylase 501 3NKAN Polysaccharide deacetylase G METABOLISM Carbohydrate transport and metabolism ACIAD0601 CDS +3 590865 591632 no putative lipopolysaccharide core biosynthesis glycosyl transferase LpsC 511 3NK6S COG0463 Glycosyltransferases involved in cell wall biogenesis M CELLULAR PROCESSES AND SIGNALING Cell wall/membrane/envelope biogenesis ACIAD0602 CDS +2 591638 592678 no putative glycosyltransferase 675 3NKPC Glycosyl transferases group 1 M CELLULAR PROCESSES AND SIGNALING Cell wall/membrane/envelope biogenesis ACIAD0603 CDS -1 592679 593563 no conserved hypothetical protein 624 3NMGU Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus J INFORMATION STORAGE AND PROCESSING Translation, ribosomal structure and biogenesis ACIAD0604 CDS +1 593638 594396 no putative glycosyltransferase involved in LPS biosynthesis 498 3NTK6 Glycosyltransferase family 25 (LPS biosynthesis protein) M CELLULAR PROCESSES AND SIGNALING Cell wall/membrane/envelope biogenesis ACIAD0605 CDS +3 594486 595325 no putative glycosyl transferase 556 3NNC3 Evidence 3 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology S POORLY CHARACTERIZED Function unknown ACIAD0606 CDS +2 595319 596098 no conserved hypothetical protein 531 2ZRFQ S POORLY CHARACTERIZED Function unknown ACIAD0607 CDS -1 596126 596884 no conserved hypothetical protein 522 3NR4V S POORLY CHARACTERIZED Function unknown ACIAD0608 CDS -3 596922 597140 no conserved hypothetical protein; putative membrane protein 143 3NPAY S POORLY CHARACTERIZED Function unknown ACIAD0609 CDS -2 597289 599127 no aspS aspartyl-tRNA synthetase 1216 3NJ1X Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn) J INFORMATION STORAGE AND PROCESSING Translation, ribosomal structure and biogenesis ACIAD0610 CDS -3 599217 599993 no conserved hypothetical protein; putative membrane protein 533 3NSU3 Zinc dependent phospholipase C S POORLY CHARACTERIZED Function unknown ACIAD0611 CDS +1 600145 602226 no putative TonB-dependent receptor protein 1348 3NJ92 TonB-dependent receptor P METABOLISM Inorganic ion transport and metabolism ACIAD0612 CDS +3 602436 604517 no putative TonB-dependent receptor protein 1405 3NJ92 TonB-dependent receptor P METABOLISM Inorganic ion transport and metabolism ACIAD0613 CDS +1 604645 606123 no conserved hypothetical protein 984 3NJBG PLD-like domain I METABOLISM Lipid transport and metabolism ACIAD0615 CDS -3 606357 606821 no conserved hypothetical protein 329 3NIPX S POORLY CHARACTERIZED Function unknown ACIAD0616 CDS +3 606954 607445 no hypothetical protein; putative signal peptide 77.4 3NM39 Nickel/cobalt transporter regulator S POORLY CHARACTERIZED Function unknown ACIAD0618 CDS +1 607570 607917 no conserved hypothetical protein; putative signal peptide 245 3NN9V Nickel/cobalt transporter regulator S POORLY CHARACTERIZED Function unknown ACIAD0620 CDS +1 608149 608586 no hypothetical protein; putative signal peptide 315 3NP5M Nickel/cobalt transporter regulator S POORLY CHARACTERIZED Function unknown ACIAD0621 CDS -2 608617 609111 no conserved hypothetical protein; putative membrane protein 315 3NM9Q Phosphate-starvation-inducible E S POORLY CHARACTERIZED Function unknown ACIAD0622 CDS +2 609257 609883 no conserved hypothetical protein; putative transcriptional regulator 424 3NJHR Putative FMN-binding domain K INFORMATION STORAGE AND PROCESSING Transcription ACIAD0623 CDS -2 609925 611715 no acdA acyl-CoA dehydrogenase 1177 3NIH3 acyl-CoA dehydrogenase I METABOLISM Lipid transport and metabolism ACIAD0624 CDS -2 611878 613755 no acdB acyl-CoA dehydrogenase 1254 3NJ9C acyl-CoA dehydrogenase I METABOLISM Lipid transport and metabolism ACIAD0625 CDS -1 613979 614296 no conserved hypothetical protein; putative signal peptide 210 3NNEC S POORLY CHARACTERIZED Function unknown ACIAD0626 CDS +1 614467 616164 no baeS kinase sensor component of a two component signal transduction system 1089 3NJFP HAMP (Histidine kinases, Adenylyl cyclases, Methyl binding proteins, Phosphatases) domain T CELLULAR PROCESSES AND SIGNALING Signal transduction mechanisms ACIAD0627 CDS +1 616168 616854 no baeR transcriptional regulator protein (OmpR family),response regulator in two-component regulatory system with BaeS, regulates RNA synthesis 455 3NIJD Transcriptional regulatory protein, C terminal K INFORMATION STORAGE AND PROCESSING Transcription ACIAD0628 CDS -2 616954 617400 no conserved hypothetical protein 295 3NT9G YjbR S POORLY CHARACTERIZED Function unknown ACIAD0629 CDS -1 617510 618982 no conserved hypothetical protein 1013 3NIY2 Uncharacterized ACR, YdiU/UPF0061 family S POORLY CHARACTERIZED Function unknown ACIAD0630 CDS -2 619039 620208 no putative fatty acid desaturase 799 3NIR4 Fatty acid desaturase I METABOLISM Lipid transport and metabolism ACIAD0631 CDS +2 620456 620959 no conserved hypothetical protein; putative signal peptide 321 3NM0G META domain O CELLULAR PROCESSES AND SIGNALING Posttranslational modification, protein turnover, chaperones ACIAD0632 CDS -3 620988 621704 no putative glycerophosphodiester phosphodiesterase 482 3NJY5 Glycerophosphoryl diester phosphodiesterase family C METABOLISM Energy production and conversion ACIAD0633 CDS -3 621744 622322 no putative cobalamin adenosyltransferase 381 3NJ04 Cobalamin adenosyltransferase S POORLY CHARACTERIZED Function unknown ACIAD0634 CDS -2 622432 624327 no putative TonB-dependent Outer membrane receptor for vitamin B12/cobalamin transport (Btub) 1231 3NK1V TonB dependent receptor P METABOLISM Inorganic ion transport and metabolism ACIAD0635 CDS +1 624670 625344 no trpF N-(5'-phosphoribosyl)anthranilate isomerase (PRAI) 445 3NIWQ Belongs to the TrpF family E METABOLISM Amino acid transport and metabolism ACIAD0636 CDS +2 625346 626557 no trpB tryptophan synthase beta chain 810 3NJAP The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine E METABOLISM Amino acid transport and metabolism ACIAD0638 CDS +2 626627 627154 no conserved hypothetical protein 367 3NIZQ Domain of Unknown Function (DUF1543) S POORLY CHARACTERIZED Function unknown ACIAD0639 CDS +3 627198 628238 no conserved hypothetical protein 729 3NTK5 Protein of unknown function (DUF2804) G METABOLISM Carbohydrate transport and metabolism ACIAD0640 CDS -2 628267 629142 no conserved hypothetical protein 587 3NIEU Predicted metal-dependent hydrolase S POORLY CHARACTERIZED Function unknown ACIAD0641 CDS +3 629208 630293 no putative transcriptional regulator 691 3NKR2 Arabinose-binding domain of AraC transcription regulator, N-term K INFORMATION STORAGE AND PROCESSING Transcription ACIAD0642 CDS +3 630720 631523 no trpA tryptophan synthase alpha chain 484 3NKMT The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3- phosphate E METABOLISM Amino acid transport and metabolism ACIAD0643 CDS +2 631520 632416 no accD acetylCoA carboxylase, beta subunit 586 3NIWH Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA I METABOLISM Lipid transport and metabolism ACIAD0644 CDS +1 632413 633699 no folC bifunctional protein [Includes: folylpolyglutamate synthase (FPGS); dihydrofolate synthase ]. 836 3NIXN Belongs to the folylpolyglutamate synthase family H METABOLISM Coenzyme transport and metabolism ACIAD0645 CDS +3 633696 634685 no conserved hypothetical protein 380 3NIQJ Sporulation related domain M CELLULAR PROCESSES AND SIGNALING Cell wall/membrane/envelope biogenesis ACIAD0646 CDS -1 634874 635698 no conserved hypothetical protein; putative AHL-lactonase 570 3NK5U Metallo-beta-lactamase superfamily S POORLY CHARACTERIZED Function unknown ACIAD0647 CDS -2 635833 636489 no putative antioxidant protein 446 3NJUS C-terminal domain of 1-Cys peroxiredoxin O CELLULAR PROCESSES AND SIGNALING Posttranslational modification, protein turnover, chaperones ACIAD0648 CDS +3 636816 639533 no secA preprotein translocase, secretion protein of IISP family 1768 3NJG7 Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving both as a receptor for the preprotein-SecB complex and as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane U CELLULAR PROCESSES AND SIGNALING Intracellular trafficking, secretion, and vesicular transport ACIAD0649 CDS +1 639688 640044 no conserved hypothetical protein; putative signal peptide 210 3NPEK S POORLY CHARACTERIZED Function unknown ACIAD0650 CDS +2 640190 641410 no argJ bifunctional protein [Includes: glutamate N-acetyltransferase (Ornithine acetyltransferase) (Ornithine transacetylase) (OATASE); amino-acid acetyltransferase (N-acetylglutamate synthase) (AGS)] 793 3NJGF Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate E METABOLISM Amino acid transport and metabolism ACIAD0651 CDS +1 641548 642612 no nadA quinolinate synthetase A 712 3NIF2 Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate H METABOLISM Coenzyme transport and metabolism ACIAD0653 CDS -3 643290 643769 no putative lipoprotein precursor 316 3NJ7Z Belongs to the ompA family M CELLULAR PROCESSES AND SIGNALING Cell wall/membrane/envelope biogenesis ACIAD0654 CDS -1 643787 645004 no putative signaling-related membrane protein 787 3NIVR Periplasmic sensor domain T CELLULAR PROCESSES AND SIGNALING Signal transduction mechanisms ACIAD0655 CDS -1 645011 645481 no conserved hypothetical protein 301 3NPGG Domain of unknown function (DUF4154) S POORLY CHARACTERIZED Function unknown ACIAD0657 CDS +2 651692 653140 no rpoN RNA polymerase sigma-54 factor 916 3NKPX Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released K INFORMATION STORAGE AND PROCESSING Transcription ACIAD0658 CDS +2 653294 653647 no putative sigma(54) modulation protein RpoX 225 3NNGT Sigma 54 modulation protein / S30EA ribosomal protein J INFORMATION STORAGE AND PROCESSING Translation, ribosomal structure and biogenesis ACIAD0659 CDS +1 653725 654033 no putative toluene tolerance protein Ttg2F 199 3NNZ6 Belongs to the BolA IbaG family K INFORMATION STORAGE AND PROCESSING Transcription ACIAD0660 CDS +1 654040 655296 no murA UDP-N-acetylglucosamine 1-carboxyvinyltransferase (Enoylpyruvate transferase) (UDP-N-acetylglucosamine enolpyruvyl transferase) (EPT) 801 3NIUB Belongs to the EPSP synthase family. MurA subfamily M CELLULAR PROCESSES AND SIGNALING Cell wall/membrane/envelope biogenesis ACIAD0661 CDS +3 655293 655979 no hisG ATP-phosphoribosyltransferase 443 3NIG8 Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity E METABOLISM Amino acid transport and metabolism ACIAD0663 CDS +1 656263 657555 no hisD Histidinol dehydrogenase (HDH) 816 3NJH3 Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine E METABOLISM Amino acid transport and metabolism ACIAD0664 CDS +2 657635 658720 no hisC histidinol-phosphate aminotransferase 702 3NIR7 Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily E METABOLISM Amino acid transport and metabolism ACIAD0665 CDS -2 658717 660027 no pabB p-aminobenzoate synthetase 876 3NIKM chorismate binding enzyme E METABOLISM Amino acid transport and metabolism ACIAD0665 CDS -2 658717 660027 no pabB p-aminobenzoate synthetase 876 3NIKM chorismate binding enzyme H METABOLISM Coenzyme transport and metabolism ACIAD0666 CDS +2 660329 661195 no putative pilus subunit (FilA) 520 3NJ6W S POORLY CHARACTERIZED Function unknown ACIAD0667 CDS +2 661508 662242 no putative pilus assembly protein (FilB) 489 3NJZ5 Peptidase C39 family S POORLY CHARACTERIZED Function unknown ACIAD0668 CDS +2 662264 663454 no putative pilus assembly protein (FilC) 737 3NJSP Sh3 type 3 domain protein T CELLULAR PROCESSES AND SIGNALING Signal transduction mechanisms ACIAD0669 CDS +1 663469 665133 no putative pilus assembly protein (FilD) 1085 3NKFA Outer membrane protein transport protein (OMPP1/FadL/TodX) I METABOLISM Lipid transport and metabolism ACIAD0671 CDS +3 665409 666356 no putative pilus assembly protein (FilE) 607 3NK0R S POORLY CHARACTERIZED Function unknown ACIAD0672 CDS +3 666375 668282 no putative pilus assembly protein (FilF) 1226 3NKJW S POORLY CHARACTERIZED Function unknown ACIAD0673 CDS -3 668325 668885 no putative MutT/nudix family protein 392 3NJ77 Nudix N-terminal F METABOLISM Nucleotide transport and metabolism ACIAD0674 CDS +2 668987 669601 no putative MutT/nudix family protein 405 3NIEC NUDIX domain L INFORMATION STORAGE AND PROCESSING Replication, recombination and repair ACIAD0675 CDS +3 669627 670169 no conserved hypothetical protein; putative anhydratase 297 3NKGF Hexapeptide repeat of succinyl-transferase S POORLY CHARACTERIZED Function unknown ACIAD0677 CDS +1 670276 670941 no putative glycoprotein endopeptidase metalloprotease 430 3NJA8 Glycoprotease family O CELLULAR PROCESSES AND SIGNALING Posttranslational modification, protein turnover, chaperones ACIAD0678 CDS +1 670954 671778 no uppP Undecaprenyl-diphosphatase (Undecaprenyl pyrophosphate phosphatase) 519 3NJBJ Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin V CELLULAR PROCESSES AND SIGNALING Defense mechanisms ACIAD0679 CDS +3 671772 672584 no conserved hypothetical protein; putative methyltransferase 540 3NJ9H Specifically methylates the guanosine in position 1516 of 16S rRNA J INFORMATION STORAGE AND PROCESSING Translation, ribosomal structure and biogenesis ACIAD0681 CDS +2 672713 674146 no abrp peptidase C13 family 956 3NKND Peptidase C13 family S POORLY CHARACTERIZED Function unknown ACIAD0682 CDS +3 674124 674954 no putative S-formylglutathione hydrolase (frmC) 575 3NJT1 Serine hydrolase involved in the detoxification of formaldehyde S POORLY CHARACTERIZED Function unknown ACIAD0683 CDS -3 675027 675302 no conserved hypothetical protein 177 3NSSM Uncharacterized protein conserved in bacteria (DUF2218) S POORLY CHARACTERIZED Function unknown ACIAD0685 CDS +1 675484 676170 no rpe D-ribulose-5-phosphate 3-epimerase 454 3NK0D Belongs to the ribulose-phosphate 3-epimerase family G METABOLISM Carbohydrate transport and metabolism ACIAD0686 CDS +2 676544 677002 no conserved hypothetical protein; putative signal peptide 89.4 3NPVD S POORLY CHARACTERIZED Function unknown ACIAD0687 CDS +3 677061 678821 no pcoA copper resistance protein A precursor 1187 3NJ08 Multicopper oxidase Q METABOLISM Secondary metabolites biosynthesis, transport and catabolism ACIAD0688 CDS +1 678808 679638 no pcoB copper resistance protein B precursor 551 3NJ7C Copper resistance protein B precursor (CopB) P METABOLISM Inorganic ion transport and metabolism ACIAD0689 CDS +1 679663 680661 no conserved hypothetical protein; putative membrane protein 626 3NKCQ Cation efflux family P METABOLISM Inorganic ion transport and metabolism ACIAD0691 CDS +2 680798 681118 no sugE suppressor of gro 190 3NNW2 Small Multidrug Resistance protein U CELLULAR PROCESSES AND SIGNALING Intracellular trafficking, secretion, and vesicular transport ACIAD0692 CDS +2 681122 681625 no ogt methylated-DNA--protein-cysteine methyltransferase (6-O- methylguanine-DNA methyltransferase) (O-6-methylguanine-DNA- alkyltransferase) 333 3NM1X Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated L INFORMATION STORAGE AND PROCESSING Replication, recombination and repair ACIAD0693 CDS -1 681683 682129 no conserved hypothetical protein 310 3NT76 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily S POORLY CHARACTERIZED Function unknown ACIAD0694 CDS -2 682261 683436 no fadA 3-ketoacyl-CoA thiolase, Acetyl-CoA acetyltransferase 749 3NJYR Belongs to the thiolase family I METABOLISM Lipid transport and metabolism ACIAD0695 CDS -1 683552 684070 no putative type 4 fimbrial biogenesis protein FimT 355 3NMDE Type II transport protein GspH N CELLULAR PROCESSES AND SIGNALING Cell motility ACIAD0695 CDS -1 683552 684070 no putative type 4 fimbrial biogenesis protein FimT 355 3NMDE Type II transport protein GspH U CELLULAR PROCESSES AND SIGNALING Intracellular trafficking, secretion, and vesicular transport ACIAD0697 CDS +2 684455 685522 no putative Outer membrane protein precursor (OmpA-like) 702 3NJM8 Belongs to the ompA family M CELLULAR PROCESSES AND SIGNALING Cell wall/membrane/envelope biogenesis ACIAD0700 CDS -1 686192 687655 no lysP lysine-specific permease 972 3NKFB Amino acid permease E METABOLISM Amino acid transport and metabolism ACIAD0701 CDS -1 687674 688690 no rsmC ribosomal RNA small subunit methyltransferase C (rRNA (guanine-N(2)-)-methyltransferase) (16S rRNA m2G1207 methyltransferase) 682 3NIIK Specifically methylates the guanine in position 1207 of 16S rRNA in the 30S particle J INFORMATION STORAGE AND PROCESSING Translation, ribosomal structure and biogenesis ACIAD0702 CDS -1 688754 690127 no putative transporter 847 3NIRB Permease family F METABOLISM Nucleotide transport and metabolism ACIAD0703 CDS +3 690306 692138 no typA GTP-binding elongation factor family protein 1189 3NIFV GTP-binding protein TypA T CELLULAR PROCESSES AND SIGNALING Signal transduction mechanisms ACIAD0704 CDS +3 692415 692855 no mscL mechanosensitive channel 277 3NN59 Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell M CELLULAR PROCESSES AND SIGNALING Cell wall/membrane/envelope biogenesis ACIAD0705 CDS +2 693011 693358 no conserved hypothetical protein 243 3NNYP Gamma-glutamyl cyclotransferase, AIG2-like S POORLY CHARACTERIZED Function unknown ACIAD0706 CDS -2 693400 693687 no ppiC peptidyl-prolyl cis-trans isomerase precursor (PPIase) (Rotamase) 188 3NNW4 PPIC-type PPIASE domain G METABOLISM Carbohydrate transport and metabolism ACIAD0707 CDS -3 693723 694541 no mutM formamidopyrimidine-DNA glycosylase 546 3NKR9 Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates L INFORMATION STORAGE AND PROCESSING Replication, recombination and repair ACIAD0708 CDS +2 694784 696940 no putative tonB-dependent receptor protein 1456 3NJA2 TonB dependent receptor P METABOLISM Inorganic ion transport and metabolism ACIAD0709 CDS +3 696960 698072 no putative FMN oxidoreductase 747 3NK91 NADH:flavin oxidoreductase / NADH oxidase family C METABOLISM Energy production and conversion ACIAD0710 CDS +2 698138 699061 no putative transporter 559 3NIP1 Membrane transport protein S POORLY CHARACTERIZED Function unknown ACIAD0711 CDS -2 699106 699870 no conserved hypothetical protein; putative signal peptide 424 3NIFB Sel1-like repeats. S POORLY CHARACTERIZED Function unknown ACIAD0713 CDS -2 700198 700905 no putative thiol:disulphide interchange protein (DsbC-like) 473 3NT5M Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process O CELLULAR PROCESSES AND SIGNALING Posttranslational modification, protein turnover, chaperones ACIAD0714 CDS -1 701141 701863 no conserved hypothetical protein; putative Glycine cleavage T protein (aminomethyl transferase) 478 3NJ1M Aminomethyltransferase folate-binding domain S POORLY CHARACTERIZED Function unknown ACIAD0715 CDS +2 702056 702715 no putative dual specificity pseudouridine synthase for 23S rRNA and tRNAphe modification (RluA-like) 447 3NIT3 Responsible for synthesis of pseudouridine from uracil J INFORMATION STORAGE AND PROCESSING Translation, ribosomal structure and biogenesis ACIAD0716 CDS +2 702842 703225 no conserved hypothetical protein 274 3NNG7 Regulator of ribonuclease activity B S POORLY CHARACTERIZED Function unknown ACIAD0717 CDS +1 703360 703800 no conserved hypothetical protein 303 3NN7Q Activator of Hsp90 ATPase homolog 1-like protein S POORLY CHARACTERIZED Function unknown ACIAD0718 CDS +2 703877 704395 no conserved hypothetical protein; putative signal peptide 339 3NNDU Protein of unknown function (DUF2939) S POORLY CHARACTERIZED Function unknown ACIAD0719 CDS +1 704461 704805 no putative alkylphosphonate uptake protein (PhnA) in phosphonate metabolism 234 3NNJZ Alkylphosphonate utilization operon protein PhnA P METABOLISM Inorganic ion transport and metabolism ACIAD0720 CDS +3 704853 705257 no putative MutT/nudix family protein 273 3NNRI NUDIX domain L INFORMATION STORAGE AND PROCESSING Replication, recombination and repair ACIAD0721 CDS +3 705393 705731 no conserved hypothetical protein 218 3NNGN Domain of unknown function (DUF1508) S POORLY CHARACTERIZED Function unknown ACIAD0722 CDS -3 705843 707126 no nrdB ribonucleoside-diphosphate reductase, beta subunit 863 3NIY6 Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides F METABOLISM Nucleotide transport and metabolism ACIAD0724 CDS -2 707455 710280 no nrdA ribonucleoside diphosphate reductase, alpha subunit 1855 3NJ81 Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides F METABOLISM Nucleotide transport and metabolism ACIAD0726 CDS +2 710825 711541 no bfmR response regulator in two-component regulatory system (bfmR/bfmS) 465 3NIJK COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain K INFORMATION STORAGE AND PROCESSING Transcription ACIAD0727 CDS +3 711588 713228 no bfmS sensory histidine kinase in two-component regulatory system (bfmR/bfmS) 1053 3NJN2 Histidine kinase T CELLULAR PROCESSES AND SIGNALING Signal transduction mechanisms ACIAD0728 CDS -3 713280 713639 no conserved hypothetical protein 237 3NNH2 S POORLY CHARACTERIZED Function unknown ACIAD0730 CDS +1 714274 714825 no nuoA NADH dehydrogenase I chain A 350 3NJ47 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient C METABOLISM Energy production and conversion ACIAD0731 CDS +1 714832 715509 no nuoB NADH dehydrogenase I chain B 452 3NIIG NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient C METABOLISM Energy production and conversion ACIAD0733 CDS +1 715591 717378 no nuoCD NADH dehydrogenase I chain C,D 1221 3NKS1 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient C METABOLISM Energy production and conversion ACIAD0734 CDS +1 717388 717900 no nuoE NADH dehydrogenase I chain E 349 3NK9H Thioredoxin-like [2Fe-2S] ferredoxin C METABOLISM Energy production and conversion ACIAD0735 CDS +3 717897 719228 no nuoF NADH dehydrogenase I chain F 914 3NK5F NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain C METABOLISM Energy production and conversion ACIAD0736 CDS +2 719240 721924 no nuoG NADH dehydrogenase I chain G 1772 3NJ2B COG1034 NADH dehydrogenase NADH ubiquinone oxidoreductase 75 kD subunit (chain G) C METABOLISM Energy production and conversion ACIAD0737 CDS +2 721943 722944 no nuoH NADH dehydrogenase I chain H 641 3NJI6 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone C METABOLISM Energy production and conversion ACIAD0738 CDS +2 722963 723505 no nuoI NADH dehydrogenase I chain I, 2Fe-2S ferredoxin-related 340 3NIV2 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient C METABOLISM Energy production and conversion ACIAD0739 CDS +1 723502 724023 no nuoJ NADH dehydrogenase I chain J 318 3NM35 Belongs to the complex I subunit 6 family C METABOLISM Energy production and conversion ACIAD0740 CDS +3 724023 724331 no nuoK NADH-quinone oxidoreductase chain K (NADH dehydrogenase I, chain K) (NDH-1, chain K) (NUO11) 192 3NNIR NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient C METABOLISM Energy production and conversion ACIAD0741 CDS +2 724328 726223 no nuoL NADH dehydrogenase I chain L 1200 3NKWW COG1009 NADH ubiquinone oxidoreductase subunit 5 (chain L) Multisubunit Na H antiporter, MnhA subunit C METABOLISM Energy production and conversion ACIAD0741 CDS +2 724328 726223 no nuoL NADH dehydrogenase I chain L 1200 3NKWW COG1009 NADH ubiquinone oxidoreductase subunit 5 (chain L) Multisubunit Na H antiporter, MnhA subunit P METABOLISM Inorganic ion transport and metabolism ACIAD0742 CDS +3 726225 727823 no nuoM NADH dehydrogenase I chain M, membrane subunit 1051 3NK34 COG1008 NADH ubiquinone oxidoreductase subunit 4 (chain M) C METABOLISM Energy production and conversion ACIAD0743 CDS +3 727839 729323 no nuoN NADH dehydrogenase I chain N 896 3NKCK NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient C METABOLISM Energy production and conversion ACIAD0744 CDS +1 729421 730065 no upp uracil phosphoribosyltransferase 410 3NISU Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate F METABOLISM Nucleotide transport and metabolism ACIAD0745 CDS +2 730250 732391 no putative ferric siderophore receptor protein 1400 3NTJZ TonB-dependent Receptor Plug Domain P METABOLISM Inorganic ion transport and metabolism ACIAD0746 CDS -1 732464 733351 no putative transcriptional regulator (LysR family) 584 3NJYX LysR substrate binding domain K INFORMATION STORAGE AND PROCESSING Transcription ACIAD0747 CDS +3 733437 734198 no fpr ferredoxin--NADP+ reductase 511 3NJVN Oxidoreductase NAD-binding domain C METABOLISM Energy production and conversion ACIAD0748 CDS -1 734330 734752 no conserved hypothetical protein 296 3NN4Q S POORLY CHARACTERIZED Function unknown ACIAD0749 CDS +1 734908 735144 no conserved hypothetical protein 154 3NPD9 S POORLY CHARACTERIZED Function unknown ACIAD0750 CDS +1 735373 737043 no conserved hypothetical protein; putative membrane protein 1013 3NIMC Conserved TM helix M CELLULAR PROCESSES AND SIGNALING Cell wall/membrane/envelope biogenesis ACIAD0752 CDS -2 737311 738507 no putative oxidoreductase with FAD/NAD(P)-binding domain 791 3NJQ8 HI0933-like protein S POORLY CHARACTERIZED Function unknown ACIAD0753 CDS -1 738578 739462 no putative D-cysteine desulfhydrase (DcyD) 600 3NK9X Pyridoxal-phosphate dependent enzyme E METABOLISM Amino acid transport and metabolism ACIAD0754 CDS -1 739472 740074 no Putative phosphoserine phosphatase 407 3NTGK haloacid dehalogenase-like hydrolase E METABOLISM Amino acid transport and metabolism ACIAD0755 CDS -1 740156 741325 no putative multidrug resistance efflux pump 655 3NIQ3 Barrel-sandwich domain of CusB or HlyD membrane-fusion V CELLULAR PROCESSES AND SIGNALING Defense mechanisms ACIAD0756 CDS -1 741341 743002 no putative transporter (MFS superfamily) 1091 3NKWK Major facilitator superfamily E METABOLISM Amino acid transport and metabolism ACIAD0756 CDS -1 741341 743002 no putative transporter (MFS superfamily) 1091 3NKWK Major facilitator superfamily G METABOLISM Carbohydrate transport and metabolism ACIAD0756 CDS -1 741341 743002 no putative transporter (MFS superfamily) 1091 3NKWK Major facilitator superfamily P METABOLISM Inorganic ion transport and metabolism ACIAD0757 CDS -3 742995 743591 no putative transcriptional regulator (TetR-family ) 378 3NJPN Bacterial regulatory proteins, tetR family K INFORMATION STORAGE AND PROCESSING Transcription ACIAD0758 CDS +2 743759 744523 no putative methyltransferase 502 3NIYS DREV methyltransferase Q METABOLISM Secondary metabolites biosynthesis, transport and catabolism ACIAD0759 CDS +3 744567 745190 no putative threonine efflux protein (RhtC) 388 3NTES LysE type translocator E METABOLISM Amino acid transport and metabolism ACIAD0760 CDS +1 745303 745527 no conserved hypothetical protein; putative signal peptide 42.4 3NQH0 S POORLY CHARACTERIZED Function unknown ACIAD0761 CDS -2 745615 746967 no 8-oxoguanine deaminase 910 3NT47 Amidohydrolase family F METABOLISM Nucleotide transport and metabolism ACIAD0762 CDS -1 747161 748582 no putative permease 881 3NIND Permease family F METABOLISM Nucleotide transport and metabolism ACIAD0764 CDS +1 748702 749652 no putative oxidoreductase 660 3NKM0 Belongs to the iron ascorbate-dependent oxidoreductase family C METABOLISM Energy production and conversion ACIAD0765 CDS +2 749645 750436 no putative enzyme 529 1S74P hydrolases or acyltransferases (alpha beta hydrolase superfamily) S POORLY CHARACTERIZED Function unknown ACIAD0766 CDS -3 750501 751478 no conserved hypothetical protein; putative hydrolase 656 3NJR6 Metallo-beta-lactamase superfamily S POORLY CHARACTERIZED Function unknown ACIAD0767 CDS -3 751605 752516 no hypothetical protein; putative membrane protein 609 32QSX Putative phage abortive infection protein S POORLY CHARACTERIZED Function unknown ACIAD0768 CDS -1 752585 754642 no metG methionyl-tRNA synthetase 1340 3NIRS Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation J INFORMATION STORAGE AND PROCESSING Translation, ribosomal structure and biogenesis ACIAD0769 CDS -3 754824 755669 no tsx nucleoside-specific channel-forming protein 592 3NIVF Nucleoside-specific channel-forming protein, Tsx M CELLULAR PROCESSES AND SIGNALING Cell wall/membrane/envelope biogenesis ACIAD0770 CDS +2 756326 756934 no conserved hypothetical protein 212 3NN73 Membrane M CELLULAR PROCESSES AND SIGNALING Cell wall/membrane/envelope biogenesis ACIAD0772 CDS +2 757055 758308 no putative ATP-binding protein 799 3NIN7 Binds and transfers iron-sulfur (Fe-S) clusters to target apoproteins. Can hydrolyze ATP D CELLULAR PROCESSES AND SIGNALING Cell cycle control, cell division, chromosome partitioning ACIAD0773 CDS +2 758483 759358 no putative MTA/SAH nucleosidase [Includes: 5'-methylthioadenosine nucleosidase ; S-adenosylhomocysteine nucleosidase] 588 3NIHF Phosphorylase superfamily F METABOLISM Nucleotide transport and metabolism ACIAD0774 CDS -1 759359 759925 no conserved hypothetical protein; putative membrane protein 370 3NKIN Uncharacterized protein conserved in bacteria (DUF2062) S POORLY CHARACTERIZED Function unknown ACIAD0775 CDS +2 760355 760948 no conserved hypothetical protein; putative membrane protein 375 3NJKU LysE type translocator E METABOLISM Amino acid transport and metabolism ACIAD0776 CDS +3 761046 761615 no dcd deoxycytidine triphosphate deaminase 392 3NKH3 Belongs to the dCTP deaminase family F METABOLISM Nucleotide transport and metabolism ACIAD0777 CDS +3 761838 763226 no conserved hypothetical protein; putative signal peptide 867 3NIEP S POORLY CHARACTERIZED Function unknown ACIAD0778 CDS +2 763238 763870 no conserved hypothetical protein; putative signal peptide 413 3NM8A S POORLY CHARACTERIZED Function unknown ACIAD0779 CDS +3 763884 766142 no conserved hypothetical protein 1427 3NK3S S POORLY CHARACTERIZED Function unknown ACIAD0780 CDS +3 766158 767267 no conserved hypothetical protein 713 3NIQE S POORLY CHARACTERIZED Function unknown ACIAD0781 CDS +3 767415 768143 no conserved hypothetical protein DUF4882 433 3NPW1 Domain of unknown function (DUF4882) S POORLY CHARACTERIZED Function unknown ACIAD0782 CDS -3 768210 769922 no proS prolyl-tRNA synthetase 1133 3NJJ4 Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys- tRNA(Pro) is not edited by ProRS J INFORMATION STORAGE AND PROCESSING Translation, ribosomal structure and biogenesis ACIAD0783 CDS -3 770025 773126 no nolG nodulation protein precursor 1932 3NJS6 Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family V CELLULAR PROCESSES AND SIGNALING Defense mechanisms ACIAD0784 CDS -1 773150 774259 no nolF nodulation protein 674 3NM18 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family M CELLULAR PROCESSES AND SIGNALING Cell wall/membrane/envelope biogenesis ACIAD0785 CDS -2 774316 774960 no conserved hypothetical protein 410 3NKXA Pfam Transposase IS66 S POORLY CHARACTERIZED Function unknown ACIAD0786 CDS +1 775213 775596 no pilG twitching motility protein 247 3NN44 Response regulator receiver domain K INFORMATION STORAGE AND PROCESSING Transcription ACIAD0786 CDS +1 775213 775596 no pilG twitching motility protein 247 3NN44 Response regulator receiver domain T CELLULAR PROCESSES AND SIGNALING Signal transduction mechanisms ACIAD0787 CDS +3 775620 775991 no pilH twitching motility protein 249 3NN3I Response regulator receiver domain K INFORMATION STORAGE AND PROCESSING Transcription ACIAD0787 CDS +3 775620 775991 no pilH twitching motility protein 249 3NN3I Response regulator receiver domain T CELLULAR PROCESSES AND SIGNALING Signal transduction mechanisms ACIAD0788 CDS +3 775995 776513 no pilI twitching motility protein 357 3NT3W Two component signalling adaptor domain N CELLULAR PROCESSES AND SIGNALING Cell motility ACIAD0788 CDS +3 775995 776513 no pilI twitching motility protein 357 3NT3W Two component signalling adaptor domain T CELLULAR PROCESSES AND SIGNALING Signal transduction mechanisms ACIAD0789 CDS +3 776556 777989 no pilJ type IV pilus biogenesis protein 889 3NIKD Methyl-accepting chemotaxis-like domains (chemotaxis sensory transducer). N CELLULAR PROCESSES AND SIGNALING Cell motility ACIAD0789 CDS +3 776556 777989 no pilJ type IV pilus biogenesis protein 889 3NIKD Methyl-accepting chemotaxis-like domains (chemotaxis sensory transducer). T CELLULAR PROCESSES AND SIGNALING Signal transduction mechanisms ACIAD0790 CDS +3 778074 782387 no chpA component of chemotactic signal transduction system 2726 3NII0 Signal transducing histidine kinase, homodimeric domain T CELLULAR PROCESSES AND SIGNALING Signal transduction mechanisms ACIAD0791 CDS -1 782417 783550 no dapE succinyl-diaminopimelate desuccinylase 759 3NIXJ Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls E METABOLISM Amino acid transport and metabolism ACIAD0792 CDS -3 783669 783812 no ecnB bacteriolytic lipoprotein entericidin B. 91.3 3NPUB Entericidin EcnA/B family S POORLY CHARACTERIZED Function unknown ACIAD0793 CDS -1 783956 784816 no conserved hypothetical protein 620 3NK09 Domain of unknown function (DUF1853) S POORLY CHARACTERIZED Function unknown ACIAD0794 CDS +3 784959 785372 no conserved hypothetical protein; putative membrane protein 280 3NNGP Protein of unknown function (DUF454) S POORLY CHARACTERIZED Function unknown ACIAD0795 CDS +1 785365 785868 no conserved hypothetical protein 351 3NN3W L,D-transpeptidase catalytic domain S POORLY CHARACTERIZED Function unknown ACIAD0797 CDS +1 786892 787356 no conserved hypothetical protein DUF2750 311 3NM9W Protein of unknown function (DUF2750) S POORLY CHARACTERIZED Function unknown ACIAD0798 CDS -2 787435 788100 no conserved hypothetical protein; putative membrane protein 441 3NIXA DUF218 domain S POORLY CHARACTERIZED Function unknown ACIAD0799 CDS -2 788356 791001 no cysJ bifunctional protein, Includes: sulfite reductase [NADPH] flavoprotein alpha-component; iron-uptake factor 1766 3NJ5B Flavodoxin P METABOLISM Inorganic ion transport and metabolism ACIAD0800 CDS -2 791158 791718 no conserved hypothetical protein; putative membrane protein 375 3NJYM YcxB-like protein S POORLY CHARACTERIZED Function unknown ACIAD0801 CDS -3 791811 793985 no conserved hypothetical protein; putative membrane protein 1390 3NIK4 FUSC-like inner membrane protein yccS S POORLY CHARACTERIZED Function unknown ACIAD0802 CDS +2 794135 795346 no putative bicyclomycin/multidrug transport protein (MFS superfamily) 748 3NJ83 Sugar (and other) transporter E METABOLISM Amino acid transport and metabolism ACIAD0802 CDS +2 794135 795346 no putative bicyclomycin/multidrug transport protein (MFS superfamily) 748 3NJ83 Sugar (and other) transporter G METABOLISM Carbohydrate transport and metabolism ACIAD0802 CDS +2 794135 795346 no putative bicyclomycin/multidrug transport protein (MFS superfamily) 748 3NJ83 Sugar (and other) transporter P METABOLISM Inorganic ion transport and metabolism ACIAD0803 CDS -1 795407 796117 no putative nitroreductase 479 3NM2K Nitroreductase family C METABOLISM Energy production and conversion ACIAD0804 CDS +2 796487 797722 no gltS sodium/glutamate symport carrier protein 779 3NJ63 Catalyzes the sodium-dependent transport of glutamate P METABOLISM Inorganic ion transport and metabolism ACIAD0805 CDS +2 797837 799336 no putative amino-acid transport protein 957 3NIJ7 Sodium:alanine symporter family E METABOLISM Amino acid transport and metabolism ACIAD0806 CDS +3 799476 800426 no conserved hypothetical protein; putative esterase of the alpha-beta hydrolase superfamily 608 3NJFC Patatin-like phospholipase S POORLY CHARACTERIZED Function unknown ACIAD0807 CDS -2 800464 800658 no conserved hypothetical protein 64.7 3NPSK S POORLY CHARACTERIZED Function unknown ACIAD0808 CDS -1 800801 801379 no putative protease 390 3NK9P DJ-1/PfpI family S POORLY CHARACTERIZED Function unknown ACIAD0809 CDS +1 801652 802845 no sbmA microcin B17 transport protein (ABC superfamily, atp_bind and membrane) 730 3NJP0 SbmA/BacA-like family I METABOLISM Lipid transport and metabolism ACIAD0810 CDS -2 802912 803142 no hypothetical protein; putative signal peptide 105 3NQ8Y S POORLY CHARACTERIZED Function unknown ACIAD0811 CDS -3 803286 803810 no putative chromate transport protein 337 3NM75 Chromate transporter P METABOLISM Inorganic ion transport and metabolism ACIAD0812 CDS -1 803807 804376 no putative chromate transport protein 323 3NJD8 Chromate transporter P METABOLISM Inorganic ion transport and metabolism ACIAD0813 CDS +3 804477 805400 no putative transcriptional regulator (LysR family) 605 3NIVN LysR substrate binding domain K INFORMATION STORAGE AND PROCESSING Transcription ACIAD0814 CDS -2 805390 806088 no conserved hypothetical protein; putative signal peptide 482 3NKWX Domain of unknown function (DUF4850) S POORLY CHARACTERIZED Function unknown ACIAD0815 CDS +3 806277 807356 no conserved hypothetical protein 722 3NJP6 Protein of unknown function (DUF1176) S POORLY CHARACTERIZED Function unknown ACIAD0816 CDS +1 807394 808170 no conserved hypothetical protein 523 3NTIB S POORLY CHARACTERIZED Function unknown ACIAD0818 CDS +3 808377 809435 no conserved hypothetical protein 723 3NIZ3 Taurine catabolism dioxygenase TauD, TfdA family Q METABOLISM Secondary metabolites biosynthesis, transport and catabolism ACIAD0819 CDS +1 809554 810078 no conserved hypothetical protein; putative signal peptide 330 3NN4D S POORLY CHARACTERIZED Function unknown ACIAD0820 CDS +3 810384 810776 no hypothetical protein 268 3NPKX S POORLY CHARACTERIZED Function unknown ACIAD0821 CDS +3 810855 811034 no hypothetical protein 61.2 4PNYG CHAT domain S POORLY CHARACTERIZED Function unknown ACIAD0822 CDS -3 811089 812576 no gatB aspartyl/glutamyl-tRNA(Asn/Gln) amidotransferase subunit B 961 3NIRM Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln) J INFORMATION STORAGE AND PROCESSING Translation, ribosomal structure and biogenesis ACIAD0823 CDS -1 812576 814054 no gatA aspartyl/glutamyl-tRNA(Asn/Gln) amidotransferase subunit A 956 3NIMZ Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln) J INFORMATION STORAGE AND PROCESSING Translation, ribosomal structure and biogenesis ACIAD0824 CDS -3 814107 814418 no gatC aspartyl/glutamyl-tRNA(Asn/Gln) amidotransferase subunit C 194 3NNKS Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln) H METABOLISM Coenzyme transport and metabolism ACIAD0825 CDS +1 814549 815589 no mreB rod shape-determining protein 668 3NJCC Rod shape-determining protein MreB D CELLULAR PROCESSES AND SIGNALING Cell cycle control, cell division, chromosome partitioning ACIAD0826 CDS +1 815608 816465 no mreC rod shape-determining protein 551 3NJPV Involved in formation and maintenance of cell shape M CELLULAR PROCESSES AND SIGNALING Cell wall/membrane/envelope biogenesis ACIAD0828 CDS +2 816500 816943 no mreD rod shape-determining protein 299 3NN3U rod shape-determining protein MreD M CELLULAR PROCESSES AND SIGNALING Cell wall/membrane/envelope biogenesis ACIAD0829 CDS +1 816946 817497 no putative Maf-like protein 354 3NK3R Maf-like protein D CELLULAR PROCESSES AND SIGNALING Cell cycle control, cell division, chromosome partitioning ACIAD0830 CDS +1 817525 818991 no cafA ribonuclease G, endoribonuclease G (cytoplasmic axial filament protein ) 951 3NJ6P Ribonuclease E/G family J INFORMATION STORAGE AND PROCESSING Translation, ribosomal structure and biogenesis ACIAD0831 CDS +2 819128 819301 no conserved hypothetical protein 119 3NPYF S POORLY CHARACTERIZED Function unknown ACIAD0832 CDS -3 819360 820736 no wax-dgaT bifunctional protein [Includes: wax ester synthase / acyl-CoA:diacylglycerol acyltransferase] 910 3NIJ1 Protein of unknown function (DUF1298) Q METABOLISM Secondary metabolites biosynthesis, transport and catabolism ACIAD0833 CDS -3 820908 821657 no putative 5'-adenylylsulfate reductase (APS reductase) (cysH-like) 528 3NII6 Reduction of activated sulfate into sulfite E METABOLISM Amino acid transport and metabolism ACIAD0833 CDS -3 820908 821657 no putative 5'-adenylylsulfate reductase (APS reductase) (cysH-like) 528 3NII6 Reduction of activated sulfate into sulfite H METABOLISM Coenzyme transport and metabolism ACIAD0834 CDS +2 821840 822457 no putative homoserine kinase (ThrH) 421 3NJXD haloacid dehalogenase-like hydrolase E METABOLISM Amino acid transport and metabolism ACIAD0835 CDS -3 822510 823976 no putative long-chain fatty acid transport protein 952 3NK15 long-chain fatty acid transport protein I METABOLISM Lipid transport and metabolism ACIAD0837 CDS -3 824367 825299 no dusC tRNA-dihydrouridine synthase C 640 3NJKN Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines. Specifically modifies U16 in tRNAs J INFORMATION STORAGE AND PROCESSING Translation, ribosomal structure and biogenesis ACIAD0838 CDS -3 825453 826262 no conserved hypothetical protein; putative membrane protein 514 3NJ18 Cytochrome C assembly protein S POORLY CHARACTERIZED Function unknown ACIAD0839 CDS +1 826408 827820 no ffh 4.5S-RNP protein, GTP binding export factor, part of signal recognition particle with 4.5 RNA 852 3NIEX Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY. Interaction with FtsY leads to the transfer of the RNC complex to the Sec translocase for insertion into the membrane, the hydrolysis of GTP by both Ffh and FtsY, and the dissociation of the SRP-FtsY complex into the individual components U CELLULAR PROCESSES AND SIGNALING Intracellular trafficking, secretion, and vesicular transport ACIAD0840 CDS -1 827888 828619 no coaX Type III pantothenate kinase (PanK-III) 498 3NJKW Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis F METABOLISM Nucleotide transport and metabolism ACIAD0841 CDS -1 828626 829387 no putative biotin--[acetyl-CoA-carboxylase] synthetase 513 3NJ23 Biotin/lipoate A/B protein ligase family H METABOLISM Coenzyme transport and metabolism ACIAD0842 CDS +2 829418 830221 no conserved hypothetical protein; putative membrane protein 512 3NJI8 membrane transporter protein S POORLY CHARACTERIZED Function unknown ACIAD0844 CDS +1 830419 831126 no putative transcriptional regulator (GntR-family) 441 3NJQF FCD domain K INFORMATION STORAGE AND PROCESSING Transcription ACIAD0846 CDS +2 831224 834673 no putative chromosome segregation ATPases 1688 3NK8A Required for chromosome condensation and partitioning D CELLULAR PROCESSES AND SIGNALING Cell cycle control, cell division, chromosome partitioning ACIAD0847 CDS +3 834675 835652 no putative cell division protein (ZipA-like) 608 3NM5I Essential cell division protein that stabilizes the FtsZ protofilaments by cross-linking them and that serves as a cytoplasmic membrane anchor for the Z ring. Also required for the recruitment to the septal ring of downstream cell division proteins D CELLULAR PROCESSES AND SIGNALING Cell cycle control, cell division, chromosome partitioning ACIAD0848 CDS +2 835730 837760 no ligA DNA ligase 1326 3NIX0 DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA L INFORMATION STORAGE AND PROCESSING Replication, recombination and repair ACIAD0849 CDS -3 837903 838958 no putative dehydrogenase 697 3NIVW NmrA-like family G METABOLISM Carbohydrate transport and metabolism ACIAD0849 CDS -3 837903 838958 no putative dehydrogenase 697 3NIVW NmrA-like family M CELLULAR PROCESSES AND SIGNALING Cell wall/membrane/envelope biogenesis ACIAD0850 CDS +1 839089 839664 no hypothetical protein; putative signal peptide 385 3NMX3 Domain present in PSD-95, Dlg, and ZO-1/2. O CELLULAR PROCESSES AND SIGNALING Posttranslational modification, protein turnover, chaperones ACIAD0851 CDS +1 839668 839868 no conserved hypothetical protein 118 3NMX3 Domain present in PSD-95, Dlg, and ZO-1/2. O CELLULAR PROCESSES AND SIGNALING Posttranslational modification, protein turnover, chaperones ACIAD0852 CDS +1 840124 840588 no bfrA bacterioferritin 309 3NJ87 Iron-storage protein, whose ferroxidase center binds Fe(2 ) ions, oxidizes them by dioxygen to Fe(3 ), and participates in the subsequent Fe(3 ) oxide mineral core formation within the central cavity of the protein complex P METABOLISM Inorganic ion transport and metabolism ACIAD0853 CDS +3 840816 841574 no hypothetical protein 434 3NRK5 Large extracellular alpha-helical protein S POORLY CHARACTERIZED Function unknown ACIAD0854 CDS -2 841642 842217 no bcp bacterioferritin comigratory protein 387 3NM03 Redoxin O CELLULAR PROCESSES AND SIGNALING Posttranslational modification, protein turnover, chaperones ACIAD0855 CDS +2 842318 843076 no putative carboxylesterase, biotin biosynthesis (BioH) 491 3NKHP hydrolases or acyltransferases (alpha beta hydrolase superfamily) S POORLY CHARACTERIZED Function unknown ACIAD0856 CDS +2 843134 844462 no bioA adenosylmethionine-8-amino-7-oxononanoate aminotransferase 904 3NJY2 Catalyzes the transfer of the alpha-amino group from S- adenosyl-L-methionine (SAM) to 7-keto-8-aminopelargonic acid (KAPA) to form 7,8-diaminopelargonic acid (DAPA). It is the only animotransferase known to utilize SAM as an amino donor H METABOLISM Coenzyme transport and metabolism ACIAD0857 CDS +3 844449 845606 no bioF 8-amino-7-oxononanoate synthase 748 3NJNE 8-amino-7-oxononanoate synthase E METABOLISM Amino acid transport and metabolism ACIAD0858 CDS +2 845597 846364 no putative biotin biosynthesis protein (BioC) 527 3NJ8J Converts the free carboxyl group of a malonyl-thioester to its methyl ester by transfer of a methyl group from S-adenosyl- L-methionine (SAM). It allows to synthesize pimeloyl-ACP via the fatty acid synthetic pathway H METABOLISM Coenzyme transport and metabolism ACIAD0859 CDS +1 846361 847002 no bioD dethiobiotin synthetase (Dethiobiotin synthase) (DTB synthetase) (DTBS) 419 3NK0H Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring H METABOLISM Coenzyme transport and metabolism ACIAD0860 CDS -1 847070 848185 no hypothetical protein; putative signal peptide 714 3NMC4 S POORLY CHARACTERIZED Function unknown ACIAD0861 CDS -1 848321 849262 no putative ribosomal large subunit pseudouridine synthase B (Pseudouridylate synthase) (Uracil hydrolyase) 615 3NIUW Belongs to the pseudouridine synthase RsuA family J INFORMATION STORAGE AND PROCESSING Translation, ribosomal structure and biogenesis ACIAD0862 CDS -2 849304 849894 no spcB chromosome condensation and segregation factor 382 3NKDZ Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves D CELLULAR PROCESSES AND SIGNALING Cell cycle control, cell division, chromosome partitioning ACIAD0863 CDS -3 849891 850682 no scpA chromosome condensation and partitioning factor 508 3NIQM Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves D CELLULAR PROCESSES AND SIGNALING Cell cycle control, cell division, chromosome partitioning ACIAD0864 CDS +3 850965 851669 no putative acetyltransferase 495 3NM1N Acetyltransferases including N-acetylases of ribosomal proteins J INFORMATION STORAGE AND PROCESSING Translation, ribosomal structure and biogenesis ACIAD0865 CDS -3 851697 852332 no putative translation factor 426 3NJAG Belongs to the SUA5 family J INFORMATION STORAGE AND PROCESSING Translation, ribosomal structure and biogenesis ACIAD0866 CDS -1 852416 853078 no conserved hypothetical protein 454 3NJ8K Elongation factor P hydroxylase S POORLY CHARACTERIZED Function unknown ACIAD0868 CDS +2 853175 853735 no conserved hypothetical protein 373 3NIVY Uncharacterized ACR, COG1399 S POORLY CHARACTERIZED Function unknown ACIAD0869 CDS +1 853807 853992 no rpmF 50S ribosomal protein L32 121 3NPDH Belongs to the bacterial ribosomal protein bL32 family J INFORMATION STORAGE AND PROCESSING Translation, ribosomal structure and biogenesis ACIAD0870 CDS +1 854146 855132 no fabD malonyl-CoA-[acyl-carrier-protein] transacylase 617 3NJ3E malonyl CoA-acyl carrier protein transacylase I METABOLISM Lipid transport and metabolism ACIAD0871 CDS +3 855129 855863 no fabG 3-oxoacyl-[acyl-carrier-protein] reductase 462 3NJEU KR domain I METABOLISM Lipid transport and metabolism ACIAD0871 CDS +3 855129 855863 no fabG 3-oxoacyl-[acyl-carrier-protein] reductase 462 3NJEU KR domain Q METABOLISM Secondary metabolites biosynthesis, transport and catabolism ACIAD0872 CDS +1 855841 856185 no acpP acyl carrier protein (ACP) 219 3NPBD Carrier of the growing fatty acid chain in fatty acid biosynthesis I METABOLISM Lipid transport and metabolism ACIAD0872 CDS +1 855841 856185 no acpP acyl carrier protein (ACP) 219 3NPBD Carrier of the growing fatty acid chain in fatty acid biosynthesis Q METABOLISM Secondary metabolites biosynthesis, transport and catabolism ACIAD0873 CDS +3 856374 856850 no putative potassium binding protein Kbp 318 3NK40 BON domain S POORLY CHARACTERIZED Function unknown ACIAD0874 CDS -1 856853 858085 no conserved hypothetical protein ; putative phage related protein 810 3NQY0 Pfam:DUF955 E METABOLISM Amino acid transport and metabolism ACIAD0875 CDS -2 858160 858939 no thiD bifunctional protein [Includes: hydroxy-methylpyrimidine kinase (HMP kinase); hydroxy-phosphomethylpyrimidine kinase (HMP-P kinase)] 506 3NJ39 Phosphomethylpyrimidine kinase H METABOLISM Coenzyme transport and metabolism ACIAD0876 CDS +2 859037 859711 no putative hydrolase 449 3NJNJ HAD-hyrolase-like S POORLY CHARACTERIZED Function unknown ACIAD0877 CDS +3 859872 860993 no putative acyltransferase 718 3NT8B Acyltransferase family I METABOLISM Lipid transport and metabolism ACIAD0878 CDS -3 861018 861470 no hemJ protoporphyrinogen oxidase 315 3NJ3T Uncharacterised protein family (UPF0093) S POORLY CHARACTERIZED Function unknown ACIAD0879 CDS -3 861789 863018 no fabB beta-ketoacyl-ACP synthase I (3-oxoacyl-[acyl-carrier-protein] synthase I) 805 3NIZM Belongs to the beta-ketoacyl-ACP synthases family I METABOLISM Lipid transport and metabolism ACIAD0879 CDS -3 861789 863018 no fabB beta-ketoacyl-ACP synthase I (3-oxoacyl-[acyl-carrier-protein] synthase I) 805 3NIZM Belongs to the beta-ketoacyl-ACP synthases family Q METABOLISM Secondary metabolites biosynthesis, transport and catabolism ACIAD0880 CDS +2 863318 864703 no conserved hypothetical protein 868 3NIRK EcsC protein family C METABOLISM Energy production and conversion ACIAD0881 CDS +3 864888 865262 no rpsL 30S ribosomal protein S12 250 3NN2Z Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit J INFORMATION STORAGE AND PROCESSING Translation, ribosomal structure and biogenesis ACIAD0883 CDS +1 865423 865893 no rpsG 30S ribosomal protein S7 292 3NM4A One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA J INFORMATION STORAGE AND PROCESSING Translation, ribosomal structure and biogenesis ACIAD0884 CDS +1 866071 868209 no fusA protein chain elongation factor EF-G, GTP-binding 1402 3NIEG Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome J INFORMATION STORAGE AND PROCESSING Translation, ribosomal structure and biogenesis ACIAD0885 CDS +2 868262 869491 no tufA protein chain elongation factor EF-Tu (duplicate of tufB) 814 3NIQ7 This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis J INFORMATION STORAGE AND PROCESSING Translation, ribosomal structure and biogenesis ACIAD0886 CDS +3 869748 870629 no conserved hypothetical protein; putative metal-dependent hydrolase 578 3NIX5 Predicted metal-dependent hydrolase S POORLY CHARACTERIZED Function unknown ACIAD0887 CDS +2 870782 871240 no rimI ribosomal-protein-alanine acetyltransferase (Acetylating enzyme for N-terminal of ribosomal protein S18) 305 3NN6W This enzyme acetylates the N-terminal alanine of ribosomal protein S18 K INFORMATION STORAGE AND PROCESSING Transcription ACIAD0888 CDS -1 871247 872062 no putative arginine-tRNA-protein transferase 564 3NJG0 May conjugate Arg from its aminoacyl-tRNA to the N- termini of proteins containing an N-terminal aspartate or glutamate O CELLULAR PROCESSES AND SIGNALING Posttranslational modification, protein turnover, chaperones ACIAD0889 CDS -1 872087 872812 no aat leucyl, phenylalanyl-tRNA-protein transferase 505 3NIET Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine O CELLULAR PROCESSES AND SIGNALING Posttranslational modification, protein turnover, chaperones ACIAD0890 CDS -1 872885 873832 no trxB thioredoxin reductase 1 613 3NJMY Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family C METABOLISM Energy production and conversion ACIAD0891 CDS +1 874099 877155 no putative cell division protein, required for chromosome partitioning (FstK) 1957 3NJRI Ftsk_gamma D CELLULAR PROCESSES AND SIGNALING Cell cycle control, cell division, chromosome partitioning ACIAD0892 CDS -1 877202 877489 no conserved hypothetical protein 198 3NNX6 S POORLY CHARACTERIZED Function unknown ACIAD0893 CDS -2 877735 878007 no minE cell division topological specificity factor (reverses minC inhibition of FtsZ ring) 173 3NNZN Prevents the cell division inhibition by proteins MinC and MinD at internal division sites while permitting inhibition at polar sites. This ensures cell division at the proper site by restricting the formation of a division septum at the midpoint of the long axis of the cell D CELLULAR PROCESSES AND SIGNALING Cell cycle control, cell division, chromosome partitioning ACIAD0894 CDS -3 878010 878846 no minD cell division inhibitor, a membrane ATPase,activates minC 536 3NJQU Belongs to the ParA family D CELLULAR PROCESSES AND SIGNALING Cell cycle control, cell division, chromosome partitioning ACIAD0895 CDS -3 878889 879611 no minC cell division inhibitor, inhibits ftsZ ring formation 456 3NTHH Cell division inhibitor that blocks the formation of polar Z ring septums. Rapidly oscillates between the poles of the cell to destabilize FtsZ filaments that have formed before they mature into polar Z rings. Prevents FtsZ polymerization D CELLULAR PROCESSES AND SIGNALING Cell cycle control, cell division, chromosome partitioning ACIAD0896 CDS -3 879735 880586 no conserved hypothetical protein; putative membrane protein 553 3NTMG Preprotein translocase subunit SecA S POORLY CHARACTERIZED Function unknown ACIAD0897 CDS -2 880798 881724 no conserved hypothetical protein; putative phospholipid/glycerol acyltransferase 630 3NJNW Phosphate acyltransferases I METABOLISM Lipid transport and metabolism ACIAD0898 CDS +2 881975 882628 no putative outer membrane protein 398 3NIW7 Belongs to the ompA family M CELLULAR PROCESSES AND SIGNALING Cell wall/membrane/envelope biogenesis ACIAD0900 CDS +1 882754 884793 no rep ATP-dependent DNA helicase 1317 3NKQE it can initiate unwinding at a nick in the DNA. It binds to the single-stranded DNA and acts in a progressive fashion along the DNA in the 3' to 5' direction L INFORMATION STORAGE AND PROCESSING Replication, recombination and repair ACIAD0901 CDS +1 884818 885270 no dut deoxyuridine 5'-triphosphate nucleotidohydrolase 304 3NJH4 This enzyme is involved in nucleotide metabolism it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA F METABOLISM Nucleotide transport and metabolism ACIAD0902 CDS +3 885462 886886 no algC phosphomannomutase 957 3NKHI Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain III G METABOLISM Carbohydrate transport and metabolism ACIAD0903 CDS +1 886897 887808 no argB acetylglutamate kinase 593 3NJA7 Belongs to the acetylglutamate kinase family. ArgB subfamily E METABOLISM Amino acid transport and metabolism ACIAD0904 CDS +1 887884 888714 no conserved hypothetical protein 570 3NKQN Acetyltransferase (GNAT) domain S POORLY CHARACTERIZED Function unknown ACIAD0905 CDS +3 888813 889670 no yafJ putative glutamine amidotransferase 583 3NIGS glutamine amidotransferase S POORLY CHARACTERIZED Function unknown ACIAD0907 CDS +2 889766 890854 no putative transporter 678 3NJQB S POORLY CHARACTERIZED Function unknown ACIAD0908 CDS +1 890851 891162 no conserved hypothetical protein 207 3NP2G Belongs to the UPF0125 (RnfH) family S POORLY CHARACTERIZED Function unknown ACIAD0909 CDS -1 891218 891616 no smpA outer membrane lipoprotein 263 3NT6T Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane M CELLULAR PROCESSES AND SIGNALING Cell wall/membrane/envelope biogenesis ACIAD0910 CDS +2 891728 892168 no fur negative regulator of ferric iron uptake 301 3NKJ7 Belongs to the Fur family K INFORMATION STORAGE AND PROCESSING Transcription ACIAD0911 CDS -1 892214 893365 no pilU twitching motility protein 741 3NKGE Type II/IV secretion system protein N CELLULAR PROCESSES AND SIGNALING Cell motility ACIAD0911 CDS -1 892214 893365 no pilU twitching motility protein 741 3NKGE Type II/IV secretion system protein U CELLULAR PROCESSES AND SIGNALING Intracellular trafficking, secretion, and vesicular transport ACIAD0912 CDS -1 893402 894436 no pilT twitching motility protein 671 3NJ7T twitching motility protein N CELLULAR PROCESSES AND SIGNALING Cell motility ACIAD0912 CDS -1 893402 894436 no pilT twitching motility protein 671 3NJ7T twitching motility protein U CELLULAR PROCESSES AND SIGNALING Intracellular trafficking, secretion, and vesicular transport ACIAD0913 CDS +3 894546 895250 no YggS Pyridoxal phosphate homeostasis protein 461 3NII3 Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis S POORLY CHARACTERIZED Function unknown ACIAD0914 CDS +1 895387 896244 no putative Undecaprenyl-diphosphatase 2 (UppP2) (Bacitracin resistance protein 2) 542 3NKQG Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin V CELLULAR PROCESSES AND SIGNALING Defense mechanisms ACIAD0915 CDS -3 896340 897125 no conserved hypothetical protein; putative transglutaminase-like enzyme 530 3NM3M Transglutaminase/protease-like homologues E METABOLISM Amino acid transport and metabolism ACIAD0916 CDS -3 897336 900932 no sbcC ATP-dependent dsDNA exonuclease (Suppression of recBC) 1972 3NJ9P Putative exonuclease SbcCD, C subunit L INFORMATION STORAGE AND PROCESSING Replication, recombination and repair ACIAD0917 CDS -3 900942 902192 no sbcD ATP-dependent dsDNA exonuclease (Suppression of recBC) 830 3NKS4 SbcCD cleaves DNA hairpin structures. These structures can inhibit DNA replication and are intermediates in certain DNA recombination reactions. The complex acts as a 3'- 5' double strand exonuclease that can open hairpins. It also has a 5' single-strand endonuclease activity L INFORMATION STORAGE AND PROCESSING Replication, recombination and repair ACIAD0918 CDS +3 902316 902789 no conserved hypothetical protein 339 3NJ4V OsmC-like protein O CELLULAR PROCESSES AND SIGNALING Posttranslational modification, protein turnover, chaperones ACIAD0919 CDS -3 902868 903437 no hypothetical protein; putative signal peptide 390 3NNB6 S POORLY CHARACTERIZED Function unknown ACIAD0920 CDS +1 903793 904248 no conserved hypothetical protein; putative membrane protein 284 3NN76 S POORLY CHARACTERIZED Function unknown ACIAD0921 CDS +1 904315 905226 no conserved hypothetical protein; putative nucleoside-diphosphate sugar epimerases (SulA family) 610 3NII9 Domain of unknown function (DUF1731) S POORLY CHARACTERIZED Function unknown ACIAD0922 CDS -3 905229 906344 no putative D-amino acid oxidase 765 3NK8N FAD dependent oxidoreductase E METABOLISM Amino acid transport and metabolism ACIAD0923 CDS -3 906369 907430 no hemB delta-aminolevulinic acid dehydratase (Porphobilinogen synthase) 699 3NIKS Belongs to the ALAD family H METABOLISM Coenzyme transport and metabolism ACIAD0924 CDS +1 907492 907989 no conserved hypothetical protein 328 3NKSH Thioesterase superfamily Q METABOLISM Secondary metabolites biosynthesis, transport and catabolism ACIAD0926 CDS +1 908317 909453 no emrA multidrug resistance secretion protein 635 3NK18 HlyD membrane-fusion protein of T1SS V CELLULAR PROCESSES AND SIGNALING Defense mechanisms ACIAD0927 CDS +1 909460 911007 no emrB multidrug resistance transmembrane protein (MFS superfamily) 979 3NJ0E Sugar (and other) transporter E METABOLISM Amino acid transport and metabolism ACIAD0927 CDS +1 909460 911007 no emrB multidrug resistance transmembrane protein (MFS superfamily) 979 3NJ0E Sugar (and other) transporter G METABOLISM Carbohydrate transport and metabolism ACIAD0927 CDS +1 909460 911007 no emrB multidrug resistance transmembrane protein (MFS superfamily) 979 3NJ0E Sugar (and other) transporter P METABOLISM Inorganic ion transport and metabolism ACIAD0929 CDS +3 911211 913172 no ggt gamma-glutamyltranspeptidase precursor 1263 3NIUX Gamma-glutamyltranspeptidase M CELLULAR PROCESSES AND SIGNALING Cell wall/membrane/envelope biogenesis ACIAD0930 CDS -3 913230 914717 no glpK glycerol kinase 976 3NIRX Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate F METABOLISM Nucleotide transport and metabolism ACIAD0931 CDS -2 915460 916092 no conserved hypothetical protein; putative membrane protein 419 3NJ89 DoxX S POORLY CHARACTERIZED Function unknown ACIAD0932 CDS +2 916256 916531 no conserved hypothetical protein 105 3NNZ4 S POORLY CHARACTERIZED Function unknown ACIAD0933 CDS +2 916604 917467 no conserved hypothetical protein 578 3NINJ Protein of unknown function (DUF692) S POORLY CHARACTERIZED Function unknown ACIAD0934 CDS +3 917418 918176 no conserved hypothetical protein 505 3NJZP Putative DNA-binding domain S POORLY CHARACTERIZED Function unknown ACIAD0935 CDS +2 918173 918793 no putative RNA polymerase sigma factor 414 3NKY6 Sigma-70, region 4 K INFORMATION STORAGE AND PROCESSING Transcription ACIAD0936 CDS +1 918787 918966 no putative anti-sigma factor 112 3NPW6 Transmembrane anti-sigma factor S POORLY CHARACTERIZED Function unknown ACIAD0937 CDS -3 919314 919973 no conserved hypothetical protein; putative membrane protein 447 3NN5I Protein of unknown function (DUF805) S POORLY CHARACTERIZED Function unknown ACIAD0939 CDS +3 921123 922922 no putative outer membrane transporter CdiB 1201 3NMBZ POTRA domain U CELLULAR PROCESSES AND SIGNALING Intracellular trafficking, secretion, and vesicular transport ACIAD0940 CDS +1 923008 934143 no cdiA toxin CdiA 5790 3NK7X Large exoproteins involved in heme utilization or adhesion U CELLULAR PROCESSES AND SIGNALING Intracellular trafficking, secretion, and vesicular transport ACIAD0941 CDS +2 934145 934615 no putative immunity CdiI protein 313 3NPB0 S POORLY CHARACTERIZED Function unknown ACIAD0943 CDS +1 935521 937062 no conserved hypothetical protein 963 1SI2C COG3209 Rhs family protein M CELLULAR PROCESSES AND SIGNALING Cell wall/membrane/envelope biogenesis ACIAD0945 CDS +2 937499 937765 no conserved hypothetical protein 175 1SI7G S POORLY CHARACTERIZED Function unknown ACIAD0946 CDS +2 937826 938071 no hypothetical protein 84.7 COG3210 domain, Protein U CELLULAR PROCESSES AND SIGNALING Intracellular trafficking, secretion, and vesicular transport ACIAD0946 CDS +2 937826 938071 no hypothetical protein 84.7 COG3210 domain, Protein U CELLULAR PROCESSES AND SIGNALING Intracellular trafficking, secretion, and vesicular transport ACIAD0947 CDS +1 938068 938910 no conserved hypothetical protein 582 3NQAI Immunity protein 49 S POORLY CHARACTERIZED Function unknown ACIAD0948 CDS +2 938996 940396 no putative hemagglutinin/hemolysin-related protein 860 3NK7X Large exoproteins involved in heme utilization or adhesion U CELLULAR PROCESSES AND SIGNALING Intracellular trafficking, secretion, and vesicular transport ACIAD0949 CDS +1 940402 940773 no hypothetical protein 247 1S74V S POORLY CHARACTERIZED Function unknown ACIAD0951 CDS +3 940911 941063 no hypothetical protein 57.4 2VY0T Immunity protein 45 S POORLY CHARACTERIZED Function unknown ACIAD0952 CDS -2 941311 942168 frameshift transposase of IS1236, IS3 family (ORF 2) 595 3NKN1 Evidence 1 Function experimentally demonstrated in the studied organism L INFORMATION STORAGE AND PROCESSING Replication, recombination and repair ACIAD0953 CDS -3 942177 942470 frameshift transposase of IS1236, IS3 family (ORF 1) 187 3NNW1 Evidence 1 Function experimentally demonstrated in the studied organism L INFORMATION STORAGE AND PROCESSING Replication, recombination and repair ACIAD0955 CDS +2 942665 943267 no conserved hypothetical protein 391 1NM19 S POORLY CHARACTERIZED Function unknown ACIAD0956 CDS -1 943379 943648 no conserved hypothetical protein 47 3NN27 nuclear chromosome segregation D CELLULAR PROCESSES AND SIGNALING Cell cycle control, cell division, chromosome partitioning ACIAD0957 CDS -3 943626 944483 frameshift transposase of IS1236, IS3 family (ORF 2) 595 3NKN1 Evidence 1 Function experimentally demonstrated in the studied organism L INFORMATION STORAGE AND PROCESSING Replication, recombination and repair ACIAD0958 CDS -1 944492 944785 frameshift transposase of IS1236, IS3 family (ORF 1) 187 3NNW1 Evidence 1 Function experimentally demonstrated in the studied organism L INFORMATION STORAGE AND PROCESSING Replication, recombination and repair ACIAD0959 CDS -1 944855 945619 no conserved hypothetical protein; putative membrane protein 461 3NN27 nuclear chromosome segregation D CELLULAR PROCESSES AND SIGNALING Cell cycle control, cell division, chromosome partitioning ACIAD0960 CDS +2 946208 947596 no putative succinate-semialdehyde dehydrogenase [NADP+] (GabD-like) 909 3NK7E Aldehyde dehydrogenase family C METABOLISM Energy production and conversion ACIAD0961 CDS -3 947697 948011 no hypothetical protein; putative signal peptide 221 3NP1T S POORLY CHARACTERIZED Function unknown ACIAD0962 CDS -3 948144 948896 no nrtR NAD-related transcriptional regulator 503 3NTMH NUDIX domain F METABOLISM Nucleotide transport and metabolism ACIAD0963 CDS -1 949007 950524 no nadV nicotinamide phosphoribosyl transferase 1004 3NJ7S Nicotinate phosphoribosyltransferase (NAPRTase) family H METABOLISM Coenzyme transport and metabolism ACIAD0964 CDS -3 950541 951422 no prs ribose-phosphate pyrophosphokinase (Phosphoribosyl pyrophosphate synthetase) 582 3NK4G Phosphoribosyl synthetase-associated domain E METABOLISM Amino acid transport and metabolism ACIAD0964 CDS -3 950541 951422 no prs ribose-phosphate pyrophosphokinase (Phosphoribosyl pyrophosphate synthetase) 582 3NK4G Phosphoribosyl synthetase-associated domain F METABOLISM Nucleotide transport and metabolism ACIAD0965 CDS +1 951754 953685 no putative phosphatase 1217 3NMSK Acid phosphatase homologues I METABOLISM Lipid transport and metabolism ACIAD0966 CDS -2 953779 954441 no putative amino acid transport protein (LysE family) 420 3NM69 LysE type translocator S POORLY CHARACTERIZED Function unknown ACIAD0967 CDS +3 954585 955478 no iciA inhibitor of replication initiation (transcriptional regulator of dnaA and argK (affects arginine transport) (LysR family)) 593 3NIIV LysR substrate binding domain K INFORMATION STORAGE AND PROCESSING Transcription ACIAD0968 CDS +3 955566 956267 no putative transcriptional regulator (GntR-family) 460 3NINZ FCD K INFORMATION STORAGE AND PROCESSING Transcription ACIAD0969 CDS -2 956269 957033 no putative iron transport protein (ABC superfamily, ATP-bind) 502 3NT1I AAA domain, putative AbiEii toxin, Type IV TA system P METABOLISM Inorganic ion transport and metabolism ACIAD0970 CDS -2 957037 958053 no putative iron transport protein (ABC superfamily, membrane) 648 3NT4A Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily P METABOLISM Inorganic ion transport and metabolism ACIAD0971 CDS -2 958057 959118 no putative iron transport protein (ABC superfamily, peri_bind) 701 3NKCI Periplasmic binding protein P METABOLISM Inorganic ion transport and metabolism ACIAD0973 CDS +3 959235 961349 no putative ferrichrome-iron receptor protein 1414 3NMD6 TonB dependent receptor P METABOLISM Inorganic ion transport and metabolism ACIAD0974 CDS -3 961392 961847 no putative acetyltransferase 320 3NN54 Acetyltransferase (GNAT) domain K INFORMATION STORAGE AND PROCESSING Transcription ACIAD0975 CDS +1 962614 963069 no hypothetical protein 306 3NP0P S POORLY CHARACTERIZED Function unknown ACIAD0977 CDS +2 963641 964639 no putative dioxygenase 685 3NSQD non-haem dioxygenase in morphine synthesis N-terminal C METABOLISM Energy production and conversion ACIAD0978 CDS +3 964806 965492 no vanR transcriptional regulator for ferulate or vanillate catabolism (GntR family) 442 3NIFR FCD K INFORMATION STORAGE AND PROCESSING Transcription ACIAD0979 CDS -2 965539 966495 no vanB vanillate O-demethylase oxidoreductase (Vanillate degradation ferredoxin-like protein) 649 3NJUK 2Fe-2S iron-sulfur cluster binding domain C METABOLISM Energy production and conversion ACIAD0980 CDS -3 966498 967574 no vanA vanillate O-demethylase oxygenase subunit (4-hydroxy-3-methoxybenzoate demethylase) 757 3NJAA Rieske [2Fe-2S] domain P METABOLISM Inorganic ion transport and metabolism ACIAD0982 CDS +1 968383 969729 no vanK vanillate transporter (MFS superfamily) 831 3NMPW Uncharacterised MFS-type transporter YbfB E METABOLISM Amino acid transport and metabolism ACIAD0982 CDS +1 968383 969729 no vanK vanillate transporter (MFS superfamily) 831 3NMPW Uncharacterised MFS-type transporter YbfB G METABOLISM Carbohydrate transport and metabolism ACIAD0982 CDS +1 968383 969729 no vanK vanillate transporter (MFS superfamily) 831 3NMPW Uncharacterised MFS-type transporter YbfB P METABOLISM Inorganic ion transport and metabolism ACIAD0983 CDS +2 969761 971044 no vanP putative porin for vanillate trafficking 870 3NKIZ outer membrane porin, OprD family S POORLY CHARACTERIZED Function unknown ACIAD0984 CDS -2 971137 972282 no putative hydroxylase involved in salicylate metabolism (SalA-like) 766 3NNDK FAD binding domain C METABOLISM Energy production and conversion ACIAD0984 CDS -2 971137 972282 no putative hydroxylase involved in salicylate metabolism (SalA-like) 766 3NNDK FAD binding domain H METABOLISM Coenzyme transport and metabolism ACIAD0985 CDS -1 972542 973354 no putative transcriptional regulator (PcaU-like) 524 3NJWG helix_turn_helix isocitrate lyase regulation K INFORMATION STORAGE AND PROCESSING Transcription ACIAD0986 CDS +3 973629 973934 no putative ferredoxin 211 3NNKW Rieske-like [2Fe-2S] domain P METABOLISM Inorganic ion transport and metabolism ACIAD0987 CDS +3 973953 974252 no conserved hypothetical protein 206 3NNVX S POORLY CHARACTERIZED Function unknown ACIAD0988 CDS +2 974261 975322 no putative vanillate O-demethylase oxygenase subunit (VanA-like) 744 3NIXQ Rieske [2Fe-2S] domain P METABOLISM Inorganic ion transport and metabolism ACIAD0989 CDS +1 975328 976098 no putative short-chain dehydrogenase 498 3NKA6 KR domain I METABOLISM Lipid transport and metabolism ACIAD0989 CDS +1 975328 976098 no putative short-chain dehydrogenase 498 3NKA6 KR domain Q METABOLISM Secondary metabolites biosynthesis, transport and catabolism ACIAD0990 CDS +2 976109 977044 no putative dioxygenase 642 3NKI2 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily E METABOLISM Amino acid transport and metabolism ACIAD0991 CDS +3 977070 978281 no putative ferredoxin reductase component (dioxygenase) 796 3NJ7D Reductase C-terminal S POORLY CHARACTERIZED Function unknown ACIAD0992 CDS +3 978348 979577 no putative permease (MFS superfamily) 773 3NK13 MFS/sugar transport protein G METABOLISM Carbohydrate transport and metabolism ACIAD0993 CDS +3 979608 980132 no conserved hypothetical protein 367 3NK0P Cupin G METABOLISM Carbohydrate transport and metabolism ACIAD0994 CDS +1 980194 981033 no putative hydrolase 553 3NTAI Serine aminopeptidase, S33 I METABOLISM Lipid transport and metabolism ACIAD0995 CDS +1 981037 981831 no putative short-chain dehydrogenase 520 3NJHF Enoyl-(Acyl carrier protein) reductase I METABOLISM Lipid transport and metabolism ACIAD0995 CDS +1 981037 981831 no putative short-chain dehydrogenase 520 3NJHF Enoyl-(Acyl carrier protein) reductase Q METABOLISM Secondary metabolites biosynthesis, transport and catabolism ACIAD0997 CDS +3 981843 982634 no L-aspartate dehydrogenase (NadX) 511 3NJIB Specifically catalyzes the NAD or NADP-dependent dehydrogenation of L-aspartate to iminoaspartate H METABOLISM Coenzyme transport and metabolism ACIAD0998 CDS +1 982648 984114 no putative aldehyde dehydrogenase 950 3NIN2 Involved in the biosynthesis of the osmoprotectant glycine betaine. Catalyzes the reversible oxidation of betaine aldehyde to the corresponding acid C METABOLISM Energy production and conversion ACIAD0999 CDS +3 984177 985817 no putative acetolactate synthase (IlvB-like) 1051 3NIP9 Thiamine pyrophosphate enzyme, central domain E METABOLISM Amino acid transport and metabolism ACIAD0999 CDS +3 984177 985817 no putative acetolactate synthase (IlvB-like) 1051 3NIP9 Thiamine pyrophosphate enzyme, central domain H METABOLISM Coenzyme transport and metabolism ACIAD1000 CDS +3 986067 987266 no conserved hypothetical protein; putative signal peptide 823 3NM8F phosphate-selective porin O and P P METABOLISM Inorganic ion transport and metabolism ACIAD1001 CDS +2 987410 988753 no putative iron-regulated membrane protein 879 3NM63 PepSY-associated TM region S POORLY CHARACTERIZED Function unknown ACIAD1002 CDS -2 988750 989241 no putative acetyltransferase (GNAT family) 335 3NNTM Acetyltransferase (GNAT) domain K INFORMATION STORAGE AND PROCESSING Transcription ACIAD1003 CDS -1 989420 991558 no putative ferric siderophore receptor protein 1436 3NIGR TonB dependent receptor P METABOLISM Inorganic ion transport and metabolism ACIAD1004 CDS +3 991629 992780 no conserved hypothetical protein; putative membrane protein 753 3NK7B Protein of unknown function (DUF1624) S POORLY CHARACTERIZED Function unknown ACIAD1005 CDS -3 992814 993299 no hypothetical protein; putative membrane protein 311 3NP5W S POORLY CHARACTERIZED Function unknown ACIAD1006 CDS -3 993363 994655 no putative permease (MFS superfamily) 810 3NMA8 Transmembrane secretion effector E METABOLISM Amino acid transport and metabolism ACIAD1006 CDS -3 993363 994655 no putative permease (MFS superfamily) 810 3NMA8 Transmembrane secretion effector G METABOLISM Carbohydrate transport and metabolism ACIAD1006 CDS -3 993363 994655 no putative permease (MFS superfamily) 810 3NMA8 Transmembrane secretion effector P METABOLISM Inorganic ion transport and metabolism ACIAD1007 CDS -1 994715 996346 no mqo malate dehydrogenase, FAD/NAD(P)-binding domain 1073 3NJ1C Malate:quinone oxidoreductase (Mqo) C METABOLISM Energy production and conversion ACIAD1008 CDS -3 996846 998507 no betA choline dehydrogenase, a flavoprotein 1140 3NK8U Involved in the biosynthesis of the osmoprotectant glycine betaine. Catalyzes the oxidation of choline to betaine aldehyde and betaine aldehyde to glycine betaine at the same rate E METABOLISM Amino acid transport and metabolism ACIAD1009 CDS -2 998596 1000068 no betB NAD+-dependent betaine aldehyde dehydrogenase 959 3NIN2 Involved in the biosynthesis of the osmoprotectant glycine betaine. Catalyzes the reversible oxidation of betaine aldehyde to the corresponding acid C METABOLISM Energy production and conversion ACIAD1010 CDS -1 1000061 1000687 no betI repressor of bet genes 405 3NK3E Repressor involved in choline regulation of the bet genes K INFORMATION STORAGE AND PROCESSING Transcription ACIAD1011 CDS +3 1000935 1002515 no BeT1 high-affinity choline transporter (BCCT family) 1026 3NK6G BCCT, betaine/carnitine/choline family transporter U CELLULAR PROCESSES AND SIGNALING Intracellular trafficking, secretion, and vesicular transport ACIAD1012 CDS +3 1002681 1004741 no betT2 high-affinity choline transporter (BCCT family) 1362 3NIKZ Belongs to the BCCT transporter (TC 2.A.15) family M CELLULAR PROCESSES AND SIGNALING Cell wall/membrane/envelope biogenesis ACIAD1013 CDS +3 1004754 1005377 no putative membrane protein 393 3NJ21 MarC family integral membrane protein U CELLULAR PROCESSES AND SIGNALING Intracellular trafficking, secretion, and vesicular transport ACIAD1014 CDS -1 1005416 1006531 no putative transcriptional regulator; putative regulator of acetoin metabolisme 754 3NKVB Transcriptional regulator K INFORMATION STORAGE AND PROCESSING Transcription ACIAD1014 CDS -1 1005416 1006531 no putative transcriptional regulator; putative regulator of acetoin metabolisme 754 3NKVB Transcriptional regulator Q METABOLISM Secondary metabolites biosynthesis, transport and catabolism ACIAD1015 CDS -3 1006746 1007777 no lipA lipoate synthase 701 3NKU5 Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives H METABOLISM Coenzyme transport and metabolism ACIAD1017 CDS +3 1008126 1009088 no acoA Acetoin dehydrogenase E1 component alpha-subunit 630 3NJJY Dehydrogenase E1 component C METABOLISM Energy production and conversion ACIAD1018 CDS +3 1009104 1010123 no acoB Acetoin dehydrogenase E1 component beta-subunit 669 3NKUU Transketolase, C-terminal domain C METABOLISM Energy production and conversion ACIAD1019 CDS +1 1010125 1011666 no acoC dihydrolipoamide acetyltransferase component (E2) of acetoin dehydrogenase complex 974 3NKCE 2-oxoacid dehydrogenases acyltransferase (catalytic domain) C METABOLISM Energy production and conversion ACIAD1020 CDS +2 1011671 1013077 no acoD Dihydrolipoyl dehydrogenase (E3 component of acetoin cleaving system) (Dihydrolipoamide dehydrogenase) 919 3NMC8 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain C METABOLISM Energy production and conversion ACIAD1021 CDS +1 1013095 1014210 no putative acetoin reductase/2,3-butanediol dehydrogenase (bdhA) 730 3NK16 Alcohol dehydrogenase GroES-like domain C METABOLISM Energy production and conversion ACIAD1022 CDS +1 1014220 1015035 no butA Diacetyl reductase 520 3NKI6 COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) I METABOLISM Lipid transport and metabolism ACIAD1022 CDS +1 1014220 1015035 no butA Diacetyl reductase 520 3NKI6 COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) Q METABOLISM Secondary metabolites biosynthesis, transport and catabolism ACIAD1023 CDS +1 1015324 1015845 no putative acyl-CoA thioester hydrolase 341 3NJCD Thioesterase superfamily I METABOLISM Lipid transport and metabolism ACIAD1024 CDS -1 1015985 1016251 no conserved hypothetical protein; putative signal peptide 129 3NQCF S POORLY CHARACTERIZED Function unknown ACIAD1025 CDS +2 1016717 1017733 no conserved hypothetical protein; putative CobW/HypB/UreG, nucleotide-binding domain 690 3NKH4 CobW/HypB/UreG, nucleotide-binding domain S POORLY CHARACTERIZED Function unknown ACIAD1026 CDS -3 1017738 1018868 no dctA aerobic C4-dicarboxylate transport protein 696 3NT4S Belongs to the dicarboxylate amino acid cation symporter (DAACS) (TC 2.A.23) family U CELLULAR PROCESSES AND SIGNALING Intracellular trafficking, secretion, and vesicular transport ACIAD1027 CDS +2 1019216 1019746 no conserved hypothetical protein 359 3NKN5 YaeQ S POORLY CHARACTERIZED Function unknown ACIAD1028 CDS +3 1019796 1020131 no fbp peptidyl-prolyl cis-trans isomerase 226 3NNHU Peptidyl-prolyl cis-trans G METABOLISM Carbohydrate transport and metabolism ACIAD1029 CDS +2 1020509 1022584 no putative lipoprotein (Haemin storage system) (HmsF) 1383 3NJCW Hypothetical glycosyl hydrolase family 13 G METABOLISM Carbohydrate transport and metabolism ACIAD1030 CDS +2 1022591 1023865 no putative transport protein (VGP family) (Haemin storage system) (HmsR) 863 3NJ8M Glycosyl transferase family 21 M CELLULAR PROCESSES AND SIGNALING Cell wall/membrane/envelope biogenesis ACIAD1031 CDS +1 1023883 1024302 no conserved hypothetical protein; putative membrane protein 281 3NN8F PgaD-like protein S POORLY CHARACTERIZED Function unknown ACIAD1032 CDS +2 1024475 1025620 no conserved hypothetical protein; putative acyltransferase 706 3NKET Acyltransferase family I METABOLISM Lipid transport and metabolism ACIAD1033 CDS +1 1025704 1026279 no putative nucleoside/purine/pyrimidine transport protein (NMN family) (PnuC) 377 3NM04 Nicotinamide mononucleotide transporter H METABOLISM Coenzyme transport and metabolism ACIAD1034 CDS +3 1026276 1026551 no conserved hypothetical protein 189 3NPTW S POORLY CHARACTERIZED Function unknown ACIAD1035 CDS +1 1026610 1027206 no conserved hypothetical protein; putative esterase 406 3NSPB Phospholipase/Carboxylesterase S POORLY CHARACTERIZED Function unknown ACIAD1036 CDS -1 1027247 1028542 no putative permease (MFS superfamily) 800 3NKBG Major facilitator superfamily E METABOLISM Amino acid transport and metabolism ACIAD1036 CDS -1 1027247 1028542 no putative permease (MFS superfamily) 800 3NKBG Major facilitator superfamily G METABOLISM Carbohydrate transport and metabolism ACIAD1036 CDS -1 1027247 1028542 no putative permease (MFS superfamily) 800 3NKBG Major facilitator superfamily P METABOLISM Inorganic ion transport and metabolism ACIAD1037 CDS -1 1028648 1028851 no hypothetical protein; putative membrane protein 135 3NPRS S POORLY CHARACTERIZED Function unknown ACIAD1038 CDS +2 1029053 1029904 no putative phosphatase 556 3NJTV Sucrose-6F-phosphate phosphohydrolase S POORLY CHARACTERIZED Function unknown ACIAD1039 CDS +1 1029904 1030386 no def2 peptide deformylase 2 314 3NSQ3 Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions J INFORMATION STORAGE AND PROCESSING Translation, ribosomal structure and biogenesis ACIAD1040 CDS +2 1030547 1031812 no putative glutaminase 823 3NMCU Belongs to the glutaminase family E METABOLISM Amino acid transport and metabolism ACIAD1041 CDS -3 1031847 1032620 no putative transcriptional regulator (AraC family) 520 3NJBE helix_turn_helix, arabinose operon control protein K INFORMATION STORAGE AND PROCESSING Transcription ACIAD1042 CDS +2 1032731 1033945 no fsr fosmidomycin/multidrug transport protein (MFS superfamily) 758 3NJX2 Major Facilitator Superfamily P METABOLISM Inorganic ion transport and metabolism ACIAD1044 CDS +1 1034335 1034628 no putative cold shock protein 189 3NP0Z Cold shock protein domain K INFORMATION STORAGE AND PROCESSING Transcription ACIAD1045 CDS -1 1034669 1038355 no metH methionine synthase (B12-dependent homocysteine-N5-methyltetrahydrofolate transmethylase, repressor of metE and metF) 2446 3NJ8A B12 binding domain E METABOLISM Amino acid transport and metabolism ACIAD1047 CDS +3 1038795 1040423 no pit phosphate transporter 1034 3NJUD Phosphate transporter family P METABOLISM Inorganic ion transport and metabolism ACIAD1048 CDS +3 1040556 1041881 no dsdA D-serine deaminase (dehydratase) 890 3NKT6 Belongs to the serine threonine dehydratase family. DsdA subfamily E METABOLISM Amino acid transport and metabolism ACIAD1049 CDS -1 1041917 1043467 no conserved hypothetical protein 1043 3NKMN mannose-ethanolamine phosphotransferase activity S POORLY CHARACTERIZED Function unknown ACIAD1051 CDS -1 1043675 1044298 no putative rhomboid protease 408 3NKSF Rhomboid family S POORLY CHARACTERIZED Function unknown ACIAD1052 CDS +2 1044449 1045087 no putative factor of maturation of Fe/S proteins (NfuA) 431 3NJ8Q Involved in iron-sulfur cluster biogenesis. Binds a 4Fe- 4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe S proteins. Could also act as a scaffold chaperone for damaged Fe S proteins C METABOLISM Energy production and conversion ACIAD1053 CDS +3 1045245 1047422 no pfeA ferric enterobactin receptor precursor 1452 3NKWC TonB dependent receptor P METABOLISM Inorganic ion transport and metabolism ACIAD1054 CDS +2 1047677 1049914 no putative ferric siderophore receptor protein 1447 3NKWC TonB dependent receptor P METABOLISM Inorganic ion transport and metabolism ACIAD1055 CDS -2 1049980 1050978 no conserved hypothetical protein 654 3NJC8 D-alanine [D-alanyl carrier protein] ligase activity Q METABOLISM Secondary metabolites biosynthesis, transport and catabolism ACIAD1056 CDS +3 1051254 1051868 no putative carbonic anhydrase 403 3NIUD Reversible hydration of carbon dioxide P METABOLISM Inorganic ion transport and metabolism ACIAD1057 CDS -1 1051907 1052542 no tesA multifunctional protein [Includes: acyl-CoA thioesterase I; protease I; lysophospholipaseL(I)] 421 3NJ8U GDSL-like Lipase/Acylhydrolase family E METABOLISM Amino acid transport and metabolism ACIAD1058 CDS +2 1052585 1053289 no putative transport protein (ABC superfamily, atp_bind) 456 3NJX6 ABC transporter Q METABOLISM Secondary metabolites biosynthesis, transport and catabolism ACIAD1059 CDS +1 1053286 1055757 no putative ABC transporter permease 1513 3NIYH FtsX-like permease family Q METABOLISM Secondary metabolites biosynthesis, transport and catabolism ACIAD1060 CDS -2 1055779 1056609 no putative rhomboid protease 541 3NJI5 membrane protein (homolog of Drosophila rhomboid) S POORLY CHARACTERIZED Function unknown ACIAD1061 CDS +2 1056689 1057363 no mtgA monofunctional biosynthetic peptidoglycan transglycosylase 451 3NIFT Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors M CELLULAR PROCESSES AND SIGNALING Cell wall/membrane/envelope biogenesis ACIAD1062 CDS +3 1057485 1059560 no ppk polyphosphate kinase 1364 3NJXP Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP) H METABOLISM Coenzyme transport and metabolism ACIAD1063 CDS -1 1059641 1060546 no estR esterase operon transcriptional regulator (LysR family) 578 3NIGA Transcriptional regulator K INFORMATION STORAGE AND PROCESSING Transcription ACIAD1064 CDS -3 1060560 1061498 no putative hydrolase (EstB) 620 3NKEF Serine aminopeptidase, S33 E METABOLISM Amino acid transport and metabolism ACIAD1065 CDS -2 1061554 1062735 no rubB rubredoxin-NAD(+) reductase 768 3NK5H Pyridine nucleotide-disulphide oxidoreductase C METABOLISM Energy production and conversion ACIAD1066 CDS -2 1062820 1062984 no rubA rubredoxin 128 3NT25 Rubredoxin C METABOLISM Energy production and conversion ACIAD1068 CDS -3 1063365 1063880 no conserved hypothetical protein 348 3NN89 Uncharacterised protein family (UPF0227) S POORLY CHARACTERIZED Function unknown ACIAD1069 CDS +1 1064137 1065666 no lysS lysyl-tRNA synthetase 1015 3NJ38 Belongs to the class-II aminoacyl-tRNA synthetase family J INFORMATION STORAGE AND PROCESSING Translation, ribosomal structure and biogenesis ACIAD1070 CDS -1 1065722 1066408 no sodM superoxide dismutase [Mn] 461 3NTEA radicals which are normally produced within the cells and which are toxic to biological systems P METABOLISM Inorganic ion transport and metabolism ACIAD1071 CDS -3 1066587 1067984 no cobQ cobyric acid synthase 932 3NQZY Catalyzes amidations at positions B, D, E, and G on adenosylcobyrinic A,C-diamide. NH(2) groups are provided by glutamine, and one molecule of ATP is hydrogenolyzed for each amidation H METABOLISM Coenzyme transport and metabolism ACIAD1072 CDS +1 1068319 1069233 no cysD sulfate adenylyltransferase subunit 2 (Sulfate adenylate transferase) (SAT) (ATP-sulfurylase small subunit) 614 3NJJG Sulfate adenylyltransferase subunit 2 H METABOLISM Coenzyme transport and metabolism ACIAD1073 CDS +2 1069286 1070899 no cysN ATP-sulfurylase, subunit 1 1026 3NJ0B Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. CysN NodQ subfamily H METABOLISM Coenzyme transport and metabolism ACIAD1074 CDS -3 1070961 1072301 no citN citrate transporter 854 3NIV0 Citrate transporter C METABOLISM Energy production and conversion ACIAD1075 CDS +1 1072870 1073373 no conserved hypothetical protein 320 3NJ6S S POORLY CHARACTERIZED Function unknown ACIAD1076 fCDS +1 1073779 1074105 pseudo fragment of conserved hypothetical protein (part 1) 194 3NJCU Domain of unknown function (DUF1989) S POORLY CHARACTERIZED Function unknown ACIAD1077 fCDS +1 1074121 1074486 pseudo fragment of conserved hypothetical protein (part 2) 198 3NJCU Domain of unknown function (DUF1989) S POORLY CHARACTERIZED Function unknown ACIAD1078 CDS +1 1074625 1076283 no putative RHS-related protein 1044 3NT02 RHS Repeat M CELLULAR PROCESSES AND SIGNALING Cell wall/membrane/envelope biogenesis ACIAD1080 CDS +3 1076289 1076612 no conserved hypothetical protein 47.8 3NP00 S POORLY CHARACTERIZED Function unknown ACIAD1081 CDS -1 1076846 1078168 no putative hemolysin-related protein 829 3NK5J Domain of unknown function DUF21 P METABOLISM Inorganic ion transport and metabolism ACIAD1082 CDS -2 1078291 1079280 no putative transcriptional regulator (LysR family) 656 3NJE5 Transcriptional regulator K INFORMATION STORAGE AND PROCESSING Transcription ACIAD1084 CDS +1 1079899 1081497 no aceA isocitrate lyase 1061 3NJIH Isocitrate lyase C METABOLISM Energy production and conversion ACIAD1085 CDS -2 1081561 1082037 no putative lipoprotein 313 3NNDC NlpE N-terminal domain M CELLULAR PROCESSES AND SIGNALING Cell wall/membrane/envelope biogenesis ACIAD1085 CDS -2 1081561 1082037 no putative lipoprotein 313 3NNDC NlpE N-terminal domain P METABOLISM Inorganic ion transport and metabolism ACIAD1087 CDS -3 1082175 1082429 no conserved hypothetical protein 160 3NPS8 S POORLY CHARACTERIZED Function unknown ACIAD1088 CDS +3 1082910 1083785 no ureD urease accessory protein 612 3NIYB Required for maturation of urease via the functional incorporation of the urease nickel metallocenter O CELLULAR PROCESSES AND SIGNALING Posttranslational modification, protein turnover, chaperones ACIAD1089 CDS +3 1083894 1084196 no ureA urease gamma subunit 193 3NNWE Belongs to the urease gamma subunit family E METABOLISM Amino acid transport and metabolism ACIAD1090 CDS +1 1084219 1084527 no ureB urease beta subunit 206 3NP3Z Belongs to the urease beta subunit family E METABOLISM Amino acid transport and metabolism ACIAD1091 CDS +1 1084558 1086258 no ureC urease alpha subunit 1137 3NINC Belongs to the metallo-dependent hydrolases superfamily. Urease alpha subunit family E METABOLISM Amino acid transport and metabolism ACIAD1092 CDS +3 1086273 1086851 no putative phosphoglycerate mutase family protein 385 3NJTD Phosphoglycerate mutase family G METABOLISM Carbohydrate transport and metabolism ACIAD1093 CDS +3 1086861 1087340 no ureE urease accessory protein 315 3NKZV Involved in urease metallocenter assembly. Binds nickel. Probably functions as a nickel donor during metallocenter assembly O CELLULAR PROCESSES AND SIGNALING Posttranslational modification, protein turnover, chaperones ACIAD1094 CDS +1 1087330 1087992 no ureF urease accessory protein 417 3NJJC Required for maturation of urease via the functional incorporation of the urease nickel metallocenter O CELLULAR PROCESSES AND SIGNALING Posttranslational modification, protein turnover, chaperones ACIAD1095 CDS +1 1088056 1088670 no ureG urease accessory protein 404 3NMI8 Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG K INFORMATION STORAGE AND PROCESSING Transcription ACIAD1095 CDS +1 1088056 1088670 no ureG urease accessory protein 404 3NMI8 Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG O CELLULAR PROCESSES AND SIGNALING Posttranslational modification, protein turnover, chaperones ACIAD1096 CDS +1 1088680 1089252 no ureJ urease accessory protein 372 3NT8P HupE / UreJ protein O CELLULAR PROCESSES AND SIGNALING Posttranslational modification, protein turnover, chaperones ACIAD1097 CDS +3 1089432 1089773 no conserved hypothetical protein 221 3NNPD S POORLY CHARACTERIZED Function unknown ACIAD1099 CDS +2 1089911 1090144 no hypothetical protein; putative signal peptide 147 3NS7H S POORLY CHARACTERIZED Function unknown ACIAD1100 CDS -2 1090168 1090713 no putative methyltransferase 355 3NK7T Specifically methylates the guanine in position 966 of 16S rRNA in the assembled 30S particle J INFORMATION STORAGE AND PROCESSING Translation, ribosomal structure and biogenesis ACIAD1101 CDS -3 1090713 1092740 no pbpA penicillin-binding protein 2 1367 3NJ50 Belongs to the transpeptidase family. MrdA subfamily M CELLULAR PROCESSES AND SIGNALING Cell wall/membrane/envelope biogenesis ACIAD1102 CDS +3 1092966 1093496 no conserved hypothetical protein; putative signal peptide 355 3NN84 S POORLY CHARACTERIZED Function unknown ACIAD1103 CDS +3 1093560 1094876 no conserved hypothetical protein; putative membrane protein 884 3NJRP protein conserved in bacteria S POORLY CHARACTERIZED Function unknown ACIAD1105 CDS +2 1094957 1095616 no adk adenylate kinase 438 3NINB Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism F METABOLISM Nucleotide transport and metabolism ACIAD1106 CDS +1 1095691 1095867 no conserved hypothetical protein 92.4 3NPXU S POORLY CHARACTERIZED Function unknown ACIAD1108 CDS -2 1095871 1096536 no nth endonuclease III DNA glycosylase/apyrimidinic (AP) lyase 445 3NKBU DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate L INFORMATION STORAGE AND PROCESSING Replication, recombination and repair ACIAD1109 CDS -2 1096552 1097304 no conserved hypothetical protein; putative iron-sulfur protein 452 3NJVT Part of a membrane complex involved in electron transport C METABOLISM Energy production and conversion ACIAD1110 CDS +2 1097660 1099003 no gdhA glutamate dehydrogenase, NADP-specific 895 3NITF Belongs to the Glu Leu Phe Val dehydrogenases family E METABOLISM Amino acid transport and metabolism ACIAD1111 CDS -2 1099066 1099743 no conserved hypothetical protein; putative signal peptide 453 3NTI3 Domain of unknown function (DUF4377) O CELLULAR PROCESSES AND SIGNALING Posttranslational modification, protein turnover, chaperones ACIAD1112 CDS -2 1100020 1100796 no conserved hypothetical protein; putative enzyme with aromatic-ring-opening dioxygenase domain 533 3NKRM Catalytic LigB subunit of aromatic ring-opening dioxygenase S POORLY CHARACTERIZED Function unknown ACIAD1113 CDS -2 1100908 1101387 no rlmH Ribosomal RNA large subunit methyltransferase H 325 3NJF6 Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA J INFORMATION STORAGE AND PROCESSING Translation, ribosomal structure and biogenesis ACIAD1115 CDS -1 1101710 1104136 no lon DNA-binding ATP-dependent protease La 1523 3NIW0 ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner O CELLULAR PROCESSES AND SIGNALING Posttranslational modification, protein turnover, chaperones ACIAD1116 CDS -3 1104282 1104917 no folN 5-formyltetrahydrofolate cyclo-ligase 433 3NINP Belongs to the 5-formyltetrahydrofolate cyclo-ligase family H METABOLISM Coenzyme transport and metabolism ACIAD1117 CDS -2 1105081 1106733 no putative membrane glycosyltransferase (GT83 family) 1083 3NJBH Dolichyl-phosphate-mannose-protein mannosyltransferase M CELLULAR PROCESSES AND SIGNALING Cell wall/membrane/envelope biogenesis ACIAD1118 CDS -2 1106740 1107144 no conserved hypothetical protein; putative membrane protein 258 3NNN8 GtrA-like protein S POORLY CHARACTERIZED Function unknown ACIAD1119 CDS -1 1107128 1108108 no putative bactoprenol glycosyl transferase, phage origin 642 3NJ1D Glycosyltransferase like family 2 M CELLULAR PROCESSES AND SIGNALING Cell wall/membrane/envelope biogenesis ACIAD1120 CDS -2 1108099 1108944 no conserved hypothetical protein 587 3NKMI YdjC-like protein G METABOLISM Carbohydrate transport and metabolism ACIAD1121 CDS -1 1109159 1110130 no lip1 lipase 643 3NT03 Serine aminopeptidase, S33 I METABOLISM Lipid transport and metabolism ACIAD1122 CDS +2 1110365 1111618 no putative RND type efflux pump involved in aminoglycoside resistance (AdeT) 828 3NIUG TRAP-type C4-dicarboxylate transport system periplasmic component G METABOLISM Carbohydrate transport and metabolism ACIAD1123 CDS -3 1111905 1112189 no conserved hypothetical protein 172 3NPD0 Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring. It is recruited early at mid-cell but it is not essential for cell division D CELLULAR PROCESSES AND SIGNALING Cell cycle control, cell division, chromosome partitioning ACIAD1124 CDS -1 1112186 1112734 no conserved hypothetical protein 181 3NJAZ S POORLY CHARACTERIZED Function unknown ACIAD1125 CDS +3 1112799 1113431 no conserved hypothetical protein 412 3NIQ2 Belongs to the UPF0149 family S POORLY CHARACTERIZED Function unknown ACIAD1126 CDS +1 1113493 1114818 no pepP aminopeptidase P 877 3NJMZ Belongs to the peptidase M24B family E METABOLISM Amino acid transport and metabolism ACIAD1127 CDS +2 1114844 1116052 no ubiH ubiH protein, 2-octaprenyl-6-methoxyphynol hydroxylase, FAD/NAD(P)-binding 786 3NK3B FAD binding domain C METABOLISM Energy production and conversion ACIAD1127 CDS +2 1114844 1116052 no ubiH ubiH protein, 2-octaprenyl-6-methoxyphynol hydroxylase, FAD/NAD(P)-binding 786 3NK3B FAD binding domain H METABOLISM Coenzyme transport and metabolism ACIAD1128 CDS +1 1116049 1117281 no ubiF 2-octaprenyl-3-methyl-6-methoxy-1,4-benzoquinol hydroxylase 802 3NIR6 Squalene epoxidase C METABOLISM Energy production and conversion ACIAD1128 CDS +1 1116049 1117281 no ubiF 2-octaprenyl-3-methyl-6-methoxy-1,4-benzoquinol hydroxylase 802 3NIR6 Squalene epoxidase H METABOLISM Coenzyme transport and metabolism ACIAD1129 CDS +2 1117454 1117705 no conserved hypothetical protein 152 3NP9Y S POORLY CHARACTERIZED Function unknown ACIAD1130 CDS -1 1117757 1118602 no putative methyltransferase 541 3NJVG Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA H METABOLISM Coenzyme transport and metabolism ACIAD1131 CDS +2 1118615 1119550 no conserved hypothetical protein; putative signal peptide 603 3NKSP LppC putative lipoprotein M CELLULAR PROCESSES AND SIGNALING Cell wall/membrane/envelope biogenesis ACIAD1132 CDS +1 1119550 1119972 no conserved hypothetical protein 285 3NP49 Belongs to the UPF0102 family L INFORMATION STORAGE AND PROCESSING Replication, recombination and repair ACIAD1133 CDS +2 1120058 1120753 no conserved hypothetical protein; putative signal peptide 432 3NJ6U BON domain S POORLY CHARACTERIZED Function unknown ACIAD1134 CDS +3 1120743 1121627 no aesT esterase 593 3NJAV Carboxylesterase family I METABOLISM Lipid transport and metabolism ACIAD1135 CDS -1 1121639 1122388 no nudC NADH pyrophosphatase (NUDIX hydrolase family) 504 3NJQ4 NADH pyrophosphatase zinc ribbon domain L INFORMATION STORAGE AND PROCESSING Replication, recombination and repair ACIAD1136 CDS -2 1122388 1124028 no conserved hypothetical protein 1033 3NJ09 Histidine kinase T CELLULAR PROCESSES AND SIGNALING Signal transduction mechanisms ACIAD1137 CDS -1 1124144 1125496 no rnhA-dnaQ bifunctional protein [Includes: ribonuclease HI; DNA polymerase III ,epsilon subunit, 3-5 exonucleolytic proofreading function] 919 3NKVD Endonuclease that specifically degrades the RNA of RNA- DNA hybrids L INFORMATION STORAGE AND PROCESSING Replication, recombination and repair ACIAD1138 CDS +3 1125708 1128929 no bifunctional protein [Includes: lytic murein transglycosylase C, membrane-bound (MtlD); putative cell wall hydrolase] 1921 3NJAK COG0741 Soluble lytic murein transglycosylase and related regulatory proteins (some contain LysM invasin domains) M CELLULAR PROCESSES AND SIGNALING Cell wall/membrane/envelope biogenesis ACIAD1139 CDS +3 1128945 1130792 no putative oligopeptide transport protein (ABC superfamily, peri_bind) 1234 3NJZZ Bacterial extracellular solute-binding proteins, family 5 Middle E METABOLISM Amino acid transport and metabolism ACIAD1140 CDS +3 1130820 1131887 no putative oligopeptide transport protein (ABC superfamily, membrane) 682 3NKGM Binding-protein-dependent transport system inner membrane component P METABOLISM Inorganic ion transport and metabolism ACIAD1141 CDS +2 1131887 1132897 no putative oligopeptide transport protein (ABC superfamily, membrane) 660 3NJ2M Binding-protein-dependent transport system inner membrane component P METABOLISM Inorganic ion transport and metabolism ACIAD1142 CDS +3 1132872 1134467 no putative oligopeptide transport protein (ABC superfamily, atp_bind) 1004 3NIPB Belongs to the ABC transporter superfamily P METABOLISM Inorganic ion transport and metabolism ACIAD1143 CDS +2 1134569 1135813 no putative FMN oxidoreductase 815 3NIRV NADH:flavin oxidoreductase / NADH oxidase family C METABOLISM Energy production and conversion ACIAD1144 CDS -1 1136210 1137109 no conserved hypothetical protein 620 3NTAU Belongs to the peptidase S1B family E METABOLISM Amino acid transport and metabolism ACIAD1145 CDS -2 1137223 1138131 no conserved hypothetical protein 605 3NTK8 Belongs to the peptidase S1B family E METABOLISM Amino acid transport and metabolism ACIAD1147 CDS -1 1138259 1139650 no putative APC family, S-methylmethionine transporter (MmuP) 917 3NJ12 amino acid E METABOLISM Amino acid transport and metabolism ACIAD1149 CDS -1 1140263 1140928 no rnt ribonuclease T (degrades tRNA , has exonuclease and ssDNAse activity) 445 3NJ5Q Trims short 3' overhangs of a variety of RNA species, leaving a one or two nucleotide 3' overhang. Responsible for the end-turnover of tRNA specifically removes the terminal AMP residue from uncharged tRNA (tRNA-C-C-A). Also appears to be involved in tRNA biosynthesis L INFORMATION STORAGE AND PROCESSING Replication, recombination and repair ACIAD1150 CDS -2 1140913 1141947 no pyrC dihydroorotase 702 3NK3G Catalyzes the reversible cyclization of carbamoyl aspartate to dihydroorotate F METABOLISM Nucleotide transport and metabolism ACIAD1151 CDS -1 1142144 1143484 no argG argininosuccinate synthetase 899 3NKG1 Belongs to the argininosuccinate synthase family. Type E METABOLISM Amino acid transport and metabolism ACIAD1152 CDS -2 1143685 1144545 no putative transcriptional regulator (LysR family) 574 3NM05 LysR substrate binding domain K INFORMATION STORAGE AND PROCESSING Transcription ACIAD1154 CDS +1 1144735 1145586 no putative transport protein 543 3NKKR EamA-like transporter family E METABOLISM Amino acid transport and metabolism ACIAD1154 CDS +1 1144735 1145586 no putative transport protein 543 3NKKR EamA-like transporter family G METABOLISM Carbohydrate transport and metabolism ACIAD1155 CDS +1 1145935 1147965 no fadH 2,4-dienoyl-CoA reductase [NADPH] (2,4-dienoyl coenzyme A reductase) 1339 3NIEV 2,4-dienoyl-coA reductase C METABOLISM Energy production and conversion ACIAD1157 CDS +1 1148683 1149891 no putative RND transporter, membrane fusion protein 761 3NJIY Barrel-sandwich domain of CusB or HlyD membrane-fusion M CELLULAR PROCESSES AND SIGNALING Cell wall/membrane/envelope biogenesis ACIAD1158 CDS +3 1149897 1152992 no putative RND efflux transporter 1916 3NJS6 Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family V CELLULAR PROCESSES AND SIGNALING Defense mechanisms ACIAD1159 CDS +2 1152989 1156096 no putative multidrug transporter 1918 3NK41 AcrB/AcrD/AcrF family V CELLULAR PROCESSES AND SIGNALING Defense mechanisms ACIAD1160 CDS +2 1156109 1157578 no putative membrane channel protein 935 3NJKG Outer membrane efflux protein M CELLULAR PROCESSES AND SIGNALING Cell wall/membrane/envelope biogenesis ACIAD1160 CDS +2 1156109 1157578 no putative membrane channel protein 935 3NJKG Outer membrane efflux protein U CELLULAR PROCESSES AND SIGNALING Intracellular trafficking, secretion, and vesicular transport ACIAD1161 CDS +2 1157618 1158133 no putative RNA polymerase sigma factor 325 3NKAU Sigma-70, region 4 K INFORMATION STORAGE AND PROCESSING Transcription ACIAD1162 CDS +3 1158159 1159133 no putative transmembrane sensor 635 3NQT9 Domain of unknown function (DUF4880) P METABOLISM Inorganic ion transport and metabolism ACIAD1162 CDS +3 1158159 1159133 no putative transmembrane sensor 635 3NQT9 Domain of unknown function (DUF4880) T CELLULAR PROCESSES AND SIGNALING Signal transduction mechanisms ACIAD1163 CDS +2 1159217 1161643 no putative ferric siderophore receptor protein 1613 1T1NA receptor P METABOLISM Inorganic ion transport and metabolism ACIAD1164 CDS +3 1162236 1163105 no hchA Chaperone protein hchA (Hsp31) 586 3NM0H DJ-1/PfpI family S POORLY CHARACTERIZED Function unknown ACIAD1165 CDS +2 1163381 1164121 no putative transcriptional regulator, luxR family 478 3NMVH Autoinducer binding domain K INFORMATION STORAGE AND PROCESSING Transcription ACIAD1166 CDS +2 1164416 1164700 partial fragment of urocanate hydratase (Urocanase) (Imidazolonepropionate hydrolase) (HutU) 104 3NM0M Catalyzes the conversion of urocanate to 4-imidazolone- 5-propionate E METABOLISM Amino acid transport and metabolism ACIAD1167 CDS +2 1164926 1165081 partial fragment of Histidine ammonia-lyase (Histidase) (HutH) 86.3 3NJM0 histidine ammonia-lyase activity E METABOLISM Amino acid transport and metabolism ACIAD1168 CDS +2 1165244 1166626 no putative histidine transport protein (APC family) 894 3NK7N Amino acid permease E METABOLISM Amino acid transport and metabolism ACIAD1169 CDS +3 1166769 1166891 partial fragment of formimidoylglutamase (Formiminoglutamase) (Formiminoglutamate hydrolase) (HutG) 57 3NJKQ Catalyzes the conversion of N-formimidoyl-L-glutamate to L-glutamate and formamide E METABOLISM Amino acid transport and metabolism ACIAD1170 CDS +3 1167042 1168301 no conserved hypothetical protein 837 3NKC5 Elongator protein 3, MiaB family, Radical SAM S POORLY CHARACTERIZED Function unknown ACIAD1171 CDS +2 1168343 1169083 no conserved hypothetical protein 502 3NJ70 Domain of unknown function (DUF4130 L INFORMATION STORAGE AND PROCESSING Replication, recombination and repair ACIAD1172 CDS -3 1169088 1169672 no conserved hypothetical protein; putative 2-hydroxychromene-2-carboxylate isomerase protein 405 3NSNE DSBA-like thioredoxin domain Q METABOLISM Secondary metabolites biosynthesis, transport and catabolism ACIAD1173 CDS -1 1169723 1170424 no putative nodulin 21-related protein 434 3NJ8Z VIT family S POORLY CHARACTERIZED Function unknown ACIAD1174 CDS +3 1170696 1171943 no conserved hypothetical protein; putative signal peptide 842 3NJ1V Tetratricopeptide repeat S POORLY CHARACTERIZED Function unknown ACIAD1175 CDS +2 1171946 1173079 no wecB UDP-N-acetyl glucosamine-2-epimerase 750 3NJE2 Belongs to the UDP-N-acetylglucosamine 2-epimerase family M CELLULAR PROCESSES AND SIGNALING Cell wall/membrane/envelope biogenesis ACIAD1176 CDS -3 1173084 1173962 no conserved hypothetical protein 611 3NJXG S POORLY CHARACTERIZED Function unknown ACIAD1177 CDS -2 1173955 1175808 no conserved hypothetical protein 1196 3NIH6 S POORLY CHARACTERIZED Function unknown ACIAD1178 CDS -3 1175805 1177058 no putative glycosyltransferase 849 3NT04 Glycosyl transferase family 21 M CELLULAR PROCESSES AND SIGNALING Cell wall/membrane/envelope biogenesis ACIAD1179 CDS -2 1177045 1177950 no conserved hypothetical protein; putative membrane protein 607 3NMER S POORLY CHARACTERIZED Function unknown ACIAD1180 CDS -3 1177950 1178696 no conserved hypothetical protein; putative membrane protein 472 3NJ7E S POORLY CHARACTERIZED Function unknown ACIAD1182 CDS -2 1178836 1180269 no phrB deoxyribodipyrimidine photolyase (photoreactivation), FAD-binding 985 3NJJE DNA photolyase L INFORMATION STORAGE AND PROCESSING Replication, recombination and repair ACIAD1183 CDS -1 1180517 1180999 no slyD FKBP-type peptidyl-prolyl cis-trans isomerase 318 3NKT2 Peptidyl-prolyl cis-trans G METABOLISM Carbohydrate transport and metabolism ACIAD1184 CDS -2 1181257 1182567 no putative D-ala-D-ala-carboxypeptidase, penicillin-binding protein 850 3NIWC Belongs to the peptidase S11 family M CELLULAR PROCESSES AND SIGNALING Cell wall/membrane/envelope biogenesis ACIAD1186 CDS +2 1182737 1184440 no conserved hypothetical protein; putative trypsin-like serine protease, typically periplasmic, contain C-terminal PDZ domain 1141 3NJ5T M61 glycyl aminopeptidase S POORLY CHARACTERIZED Function unknown ACIAD1187 CDS +1 1184683 1186914 no idh isocitrate dehydrogenase 1474 3NKCF Isocitrate dehydrogenase C METABOLISM Energy production and conversion ACIAD1188 CDS -1 1187009 1187407 no putative transthyretin-like protein 275 3NNPX Belongs to the transthyretin family. 5-hydroxyisourate hydrolase subfamily S POORLY CHARACTERIZED Function unknown ACIAD1189 CDS -1 1187492 1188286 no putative pseudouridine synthase 521 3NJCJ Belongs to the pseudouridine synthase RsuA family G METABOLISM Carbohydrate transport and metabolism ACIAD1190 CDS +2 1188428 1189738 no icd isocitrate dehydrogenase 875 3NKE6 Isocitrate/isopropylmalate dehydrogenase C METABOLISM Energy production and conversion ACIAD1191 CDS +3 1189971 1191359 no putative transport protein 811 3NKUH Belongs to the dicarboxylate amino acid cation symporter (DAACS) (TC 2.A.23) family U CELLULAR PROCESSES AND SIGNALING Intracellular trafficking, secretion, and vesicular transport ACIAD1192 CDS +3 1191486 1192316 no conserved hypothetical protein; putative epimerase, PhzC/PhzF homolog 550 3NKFK Phenazine biosynthesis-like protein S POORLY CHARACTERIZED Function unknown ACIAD1193 CDS +1 1192468 1193697 no putative chloride transport protein 791 3NJ0X Voltage gated chloride channel P METABOLISM Inorganic ion transport and metabolism ACIAD1194 CDS +3 1193808 1196588 no putative protease 1796 3NJ2D Belongs to the peptidase M16 family S POORLY CHARACTERIZED Function unknown ACIAD1195 CDS -1 1196627 1197010 no conserved hypothetical protein 254 3NN7F Protein of unknown function (DUF3144) S POORLY CHARACTERIZED Function unknown ACIAD1196 CDS +2 1197101 1197748 no conserved hypothetical protein 444 3NJW6 S POORLY CHARACTERIZED Function unknown ACIAD1197 CDS -1 1197797 1199263 no conserved hypothetical protein 932 3NJ4M CYTH S POORLY CHARACTERIZED Function unknown ACIAD1198 CDS +1 1199488 1199868 no conserved hypothetical protein 258 3NNH1 Protein of unknown function (DUF962) S POORLY CHARACTERIZED Function unknown ACIAD1199 CDS +3 1200012 1200776 no putative outer membrane W signal peptide protein 499 3NIQN OmpW family M CELLULAR PROCESSES AND SIGNALING Cell wall/membrane/envelope biogenesis ACIAD1200 CDS +3 1200906 1201541 no putative thiamin-phosphate pyrophosphorylase (ThiE) 404 3NIUK Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP) H METABOLISM Coenzyme transport and metabolism ACIAD1201 CDS +2 1201571 1202869 no hemL glutamate-1-semialdehyde aminotransferase 866 3NJSW Glutamate-1-semialdehyde aminotransferase H METABOLISM Coenzyme transport and metabolism ACIAD1202 CDS +3 1202922 1203338 no conserved hypothetical protein 266 3NN4C Haem-degrading S POORLY CHARACTERIZED Function unknown ACIAD1203 CDS +1 1203493 1204137 no rluA dual specificity pseudouridine synthase for 23S rRNA and tRNAphe modification 434 3NJ80 Pseudouridine synthase J INFORMATION STORAGE AND PROCESSING Translation, ribosomal structure and biogenesis ACIAD1204 CDS +1 1204255 1207116 no hepA RNA helicase 1865 3NJTY Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair K INFORMATION STORAGE AND PROCESSING Transcription ACIAD1205 CDS -3 1207197 1207706 no dps stress response DNA-binding protein, starvation induced resistance to H2O2, ferritin-like 326 3NJC5 During stationary phase, binds the chromosome non- specifically, forming a highly ordered and stable dps-DNA co- crystal within which chromosomal DNA is condensed and protected from diverse damages. It protects DNA from oxidative damage by sequestering intracellular Fe(2 ) ion and storing it in the form of Fe(3 ) oxyhydroxide mineral, which can be released after reduction. One hydrogen peroxide oxidizes two Fe(2 ) ions, which prevents hydroxyl radical production by the Fenton reaction P METABOLISM Inorganic ion transport and metabolism ACIAD1206 CDS -3 1207854 1208546 no putative transcriptional regulator (tetR family) 431 3NJDT Bacterial regulatory proteins, tetR family K INFORMATION STORAGE AND PROCESSING Transcription ACIAD1207 CDS +2 1208687 1209748 no putative oxidoreductase 692 3NJRK Ferric reductase NAD binding domain C METABOLISM Energy production and conversion ACIAD1208 CDS +1 1209763 1210857 no putative fatty acid desaturase 763 3NIQ6 Fatty acid desaturase I METABOLISM Lipid transport and metabolism ACIAD1209 CDS -1 1210937 1211641 no conserved hypothetical protein; putative signal peptide 432 3NJEW Protein of unknown function (DUF541) S POORLY CHARACTERIZED Function unknown ACIAD1210 CDS +2 1212116 1213486 no dat diaminobutyrate--2-oxoglutarate aminotransferase (L- diaminobutyric acid transaminase) (Diaminobutyrate transaminase) (DABA aminotransferase) (DABA-AT) (L-2,4-diaminobutyrate:2-ketoglutarate 4- aminotransferase) 904 3NJ5V Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family E METABOLISM Amino acid transport and metabolism ACIAD1211 CDS +2 1213493 1215025 no ddc L-2,4-diaminobutyrate decarboxylase 1007 3NIHU Pyridoxal-dependent decarboxylase conserved domain E METABOLISM Amino acid transport and metabolism ACIAD1212 CDS +3 1215315 1216346 no putative phosphate transporter (ABC superfamily, peri-bind) 664 3NIIE PBP superfamily domain P METABOLISM Inorganic ion transport and metabolism ACIAD1213 CDS +1 1216450 1217829 no pstC high-affinity phosphate transport protein (ABC superfamily, membrane) 840 3NK5P probably responsible for the translocation of the substrate across the membrane P METABOLISM Inorganic ion transport and metabolism ACIAD1214 CDS +3 1217826 1219223 no pstA high-affinity phosphate transport protein (ABC superfamily, membrane) 842 3NJB6 Phosphate transport system permease P METABOLISM Inorganic ion transport and metabolism ACIAD1215 CDS +2 1219235 1220146 no pstB high-affinity phosphate transport protein (ABC superfamily, atp_bind) 595 3NIWW Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system P METABOLISM Inorganic ion transport and metabolism ACIAD1216 CDS +2 1220297 1221259 no putative protease (SohB) 614 3NJ7X Peptidase family S49 N-terminal O CELLULAR PROCESSES AND SIGNALING Posttranslational modification, protein turnover, chaperones ACIAD1216 CDS +2 1220297 1221259 no putative protease (SohB) 614 3NJ7X Peptidase family S49 N-terminal U CELLULAR PROCESSES AND SIGNALING Intracellular trafficking, secretion, and vesicular transport ACIAD1217 CDS -1 1221290 1221922 no conserved hypothetical protein; putative membrane protein 420 3NTGZ Predicted membrane protein (DUF2238) S POORLY CHARACTERIZED Function unknown ACIAD1219 CDS -3 1222005 1223393 no purB adenylosuccinate lyase 908 3NIZU Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily F METABOLISM Nucleotide transport and metabolism ACIAD1220 CDS -2 1223449 1224180 no conserved hypothetical protein; putative protein involved in purine metabolism 471 3NJ85 Protein of unknown function (DUF489) S POORLY CHARACTERIZED Function unknown ACIAD1221 CDS -1 1224194 1225327 no trmU tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase 776 3NJVQ Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34 J INFORMATION STORAGE AND PROCESSING Translation, ribosomal structure and biogenesis ACIAD1222 CDS -3 1225332 1225832 no putative Nudix hydrolase 335 3NIQI Belongs to the Nudix hydrolase family. NudJ subfamily F METABOLISM Nucleotide transport and metabolism ACIAD1223 CDS -2 1225894 1226244 no conserved hypothetical protein 240 1N3R0 Glyoxalase-like domain S POORLY CHARACTERIZED Function unknown ACIAD1224 CDS -3 1226364 1226903 no putative transferase 365 3NJIS Bacterial transferase hexapeptide (six repeats) S POORLY CHARACTERIZED Function unknown ACIAD1225 CDS -2 1226995 1228143 no dacC D-ala-D-ala-carboxypeptidase; penicillin-binding protein 5 (precursor) 746 3NK5A Belongs to the peptidase S11 family M CELLULAR PROCESSES AND SIGNALING Cell wall/membrane/envelope biogenesis ACIAD1226 CDS -2 1228261 1228659 no conserved hypothetical protein; putative signal peptide 249 3NPBR S POORLY CHARACTERIZED Function unknown ACIAD1227 CDS +2 1228919 1229686 no surE 5'(3')-nucleotidase 508 3NJSQ Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates S POORLY CHARACTERIZED Function unknown ACIAD1229 CDS +3 1229817 1230650 no nlpD lipoprotein precursor 536 3NK2K Peptidase family M23 D CELLULAR PROCESSES AND SIGNALING Cell cycle control, cell division, chromosome partitioning ACIAD1229 CDS +3 1229817 1230650 no nlpD lipoprotein precursor 536 3NK2K Peptidase family M23 M CELLULAR PROCESSES AND SIGNALING Cell wall/membrane/envelope biogenesis ACIAD1230 CDS +1 1230760 1231689 no putative transcriptional regulator (LysR family) 608 3NJRH Transcriptional regulator K INFORMATION STORAGE AND PROCESSING Transcription ACIAD1231 CDS -3 1231743 1232957 no argD acetylornithine aminotransferase 798 3NKVR acetylornithine aminotransferase E METABOLISM Amino acid transport and metabolism ACIAD1232 CDS +2 1233098 1233463 no putative glutaredoxin-like protein (grxD-like) 245 3NNJH Belongs to the glutaredoxin family. Monothiol subfamily C METABOLISM Energy production and conversion ACIAD1233 CDS -3 1233525 1233869 no conserved hypothetical protein; putative exported protein 92.8 3NPD5 S POORLY CHARACTERIZED Function unknown ACIAD1234 CDS -3 1234047 1235606 no ahpF alkyl hydroperoxide reductase subunit, FAD/NAD(P)-binding, detoxification of hydroperoxides 1007 3NJBW Alkyl hydroperoxide reductase C METABOLISM Energy production and conversion ACIAD1235 CDS +1 1235794 1236063 no conserved hypothetical protein 186 3NPFG KTSC domain S POORLY CHARACTERIZED Function unknown ACIAD1236 CDS -2 1236073 1236660 no mdmC O-methyl transferase 383 3NKU9 O-methyltransferase S POORLY CHARACTERIZED Function unknown ACIAD1237 CDS -2 1236703 1236921 no conserved hypothetical protein 152 3NPEV Protein of unknown function (DUF1653) S POORLY CHARACTERIZED Function unknown ACIAD1238 CDS -1 1237130 1237573 no conserved hypothetical protein; putative universal stress protein family (Usp) 279 3NNC8 Universal stress protein family T CELLULAR PROCESSES AND SIGNALING Signal transduction mechanisms ACIAD1239 CDS -3 1238148 1238417 no hypothetical protein 180 3NRP2 S POORLY CHARACTERIZED Function unknown ACIAD1240 CDS +1 1238875 1241073 no putative ferric siderophore receptor protein 1487 3NK02 TonB dependent receptor P METABOLISM Inorganic ion transport and metabolism ACIAD1241 CDS -1 1241138 1242592 no putative sulfate transporter 905 3NIKE STAS domain P METABOLISM Inorganic ion transport and metabolism ACIAD1242 CDS +2 1243238 1243441 no conserved hypothetical protein 84.3 3NQDA S POORLY CHARACTERIZED Function unknown ACIAD1243 CDS +3 1243842 1245161 no putative transporter 814 3NJBB Permease family S POORLY CHARACTERIZED Function unknown ACIAD1245 CDS +2 1245224 1246222 no add adenosine deaminase 663 3NJMF Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism F METABOLISM Nucleotide transport and metabolism ACIAD1246 CDS -1 1246277 1246831 no putative cytochrome 377 3NIEN Prokaryotic cytochrome b561 C METABOLISM Energy production and conversion ACIAD1247 CDS +1 1247056 1247442 no conserved hypothetical protein; putative signal peptide 245 3NP35 S POORLY CHARACTERIZED Function unknown ACIAD1248 CDS +2 1247459 1248028 no rnhB RNAse HII 371 3NJ52 Endonuclease that specifically degrades the RNA of RNA- DNA hybrids L INFORMATION STORAGE AND PROCESSING Replication, recombination and repair ACIAD1249 CDS -3 1248198 1249049 frameshift transposase of IS1236, IS3 family (ORF 2) 592 3NKN1 Evidence 1 Function experimentally demonstrated in the studied organism L INFORMATION STORAGE AND PROCESSING Replication, recombination and repair ACIAD1250 CDS -1 1249064 1249357 frameshift transposase of IS1236, IS3 family (ORF 1) 187 3NNW1 Evidence 1 Function experimentally demonstrated in the studied organism L INFORMATION STORAGE AND PROCESSING Replication, recombination and repair ACIAD1251 CDS -3 1249392 1249604 no csrA carbon storage regulator 133 3NNX1 Could accelerate the degradation of some genes transcripts potentially through selective RNA binding T CELLULAR PROCESSES AND SIGNALING Signal transduction mechanisms ACIAD1252 CDS -1 1249850 1251130 no lysC aspartate kinase 808 3NKCG Belongs to the aspartokinase family E METABOLISM Amino acid transport and metabolism ACIAD1253 CDS -2 1251196 1253832 no alaS alanyl-tRNA synthetase 1728 3NIN9 Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain J INFORMATION STORAGE AND PROCESSING Translation, ribosomal structure and biogenesis ACIAD1255 CDS +2 1254293 1255315 no epd D-erythrose 4-phosphate dehydrogenase 672 3NKPI Belongs to the glyceraldehyde-3-phosphate dehydrogenase family G METABOLISM Carbohydrate transport and metabolism ACIAD1257 CDS +2 1255511 1256677 no hisZ ATP phosphoribosyltransferase 768 3NM0B Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine E METABOLISM Amino acid transport and metabolism ACIAD1258 CDS +1 1256743 1258062 no purA adenylosuccinate synthetase 878 3NJVH Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP F METABOLISM Nucleotide transport and metabolism ACIAD1259 CDS +2 1258178 1258489 no conserved hypothetical protein; putative membrane protein 205 3NPDJ S POORLY CHARACTERIZED Function unknown ACIAD1260 CDS +3 1258605 1259384 no conserved hypothetical protein; putative Zn-dependent protease with chaperone function 492 3NK04 Peptidase family M48 M CELLULAR PROCESSES AND SIGNALING Cell wall/membrane/envelope biogenesis ACIAD1261 CDS -1 1259438 1260484 no putative oxidoreductase, aldo/keto reductase family 709 3NIX3 Aldo/keto reductase family C METABOLISM Energy production and conversion ACIAD1262 CDS -3 1260645 1261274 no vfr cyclic AMP receptor protein 404 3NJS7 helix_turn_helix, cAMP Regulatory protein K INFORMATION STORAGE AND PROCESSING Transcription ACIAD1263 CDS +1 1261495 1261920 no conserved hypothetical protein 279 3NN4F OsmC-like protein O CELLULAR PROCESSES AND SIGNALING Posttranslational modification, protein turnover, chaperones ACIAD1264 CDS +1 1262026 1262451 no putative acyltransferase; putative acyltransferase for phosphonate utilization (PhnO) 285 3NPJ1 Acetyltransferase (GNAT) domain K INFORMATION STORAGE AND PROCESSING Transcription ACIAD1265 CDS +2 1262777 1265356 no clpB ATP-dependent protease, Hsp 100, part of multi-chaperone system with DnaK, DnaJ, and GrpE 1623 3NJDZ Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE O CELLULAR PROCESSES AND SIGNALING Posttranslational modification, protein turnover, chaperones ACIAD1266 CDS +3 1265604 1267433 no ilvD dihydroxy-acid dehydratase 1189 3NJMA Belongs to the IlvD Edd family E METABOLISM Amino acid transport and metabolism ACIAD1266 CDS +3 1265604 1267433 no ilvD dihydroxy-acid dehydratase 1189 3NJMA Belongs to the IlvD Edd family G METABOLISM Carbohydrate transport and metabolism ACIAD1267 CDS +1 1267642 1268082 no conserved hypothetical protein; putative signal peptide 273 3NQDD S POORLY CHARACTERIZED Function unknown ACIAD1268 CDS -2 1268101 1270305 no putative N-6 Adenine-specific DNA methylase 1477 3NKZ8 Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA J INFORMATION STORAGE AND PROCESSING Translation, ribosomal structure and biogenesis ACIAD1270 CDS +3 1270608 1271624 no pyrB aspartate carbamoyltransferase, catalytic subunit 655 3NJN7 Belongs to the ATCase OTCase family F METABOLISM Nucleotide transport and metabolism ACIAD1271 CDS +3 1271637 1272872 no pyrX aspartate carbamoyltransferase, non-catalytic chain (Dihydroorotase-like protein) 815 3NJ58 dihydroorotase F METABOLISM Nucleotide transport and metabolism ACIAD1272 CDS +1 1273021 1274040 no conserved hypothetical protein 658 3NJJ6 S POORLY CHARACTERIZED Function unknown ACIAD1273 CDS +1 1274134 1274916 no conserved hypothetical protein 508 3NSM1 Rossmann-like domain S POORLY CHARACTERIZED Function unknown ACIAD1274 CDS +1 1274947 1275615 no conserved hypothetical protein; putative SAM-dependent methyltransferase 452 3NTMI Protein of unknown function (DUF938) Q METABOLISM Secondary metabolites biosynthesis, transport and catabolism ACIAD1276 CDS +3 1276347 1277831 no putative amino acid transporter 914 3NTMJ Amino acid permease E METABOLISM Amino acid transport and metabolism ACIAD1277 CDS +2 1277828 1278715 no conserved hypothetical protein 582 1RDNJ Universal stress protein family T CELLULAR PROCESSES AND SIGNALING Signal transduction mechanisms ACIAD1279 CDS +2 1278773 1281517 no cphA Cyanophycin synthetase 1793 1RS1C GNAT family acetyltransferase H METABOLISM Coenzyme transport and metabolism ACIAD1279 CDS +2 1278773 1281517 no cphA Cyanophycin synthetase 1793 1RS1C GNAT family acetyltransferase J INFORMATION STORAGE AND PROCESSING Translation, ribosomal structure and biogenesis ACIAD1280 CDS +3 1281525 1283720 no putative Cyanophycinase (CphI/CphB) 1415 1RPCF COG4242 Cyanophycinase and related exopeptidases P METABOLISM Inorganic ion transport and metabolism ACIAD1280 CDS +3 1281525 1283720 no putative Cyanophycinase (CphI/CphB) 1415 1RPCF COG4242 Cyanophycinase and related exopeptidases Q METABOLISM Secondary metabolites biosynthesis, transport and catabolism ACIAD1281 CDS +1 1283770 1284261 no hypothetical protein 51.6 43RGI PIN domain S POORLY CHARACTERIZED Function unknown ACIAD1282 CDS +3 1284279 1285430 no putative succinylglutamate desuccinylase/aspartoacylase 772 1RSQJ peptidase m14 S POORLY CHARACTERIZED Function unknown ACIAD1283 CDS -3 1285563 1285985 no argR transcription regulator ArgR 274 1T0WU AsnC family K INFORMATION STORAGE AND PROCESSING Transcription ACIAD1284 CDS +3 1286124 1287335 no aruC Succinylornithine transaminase 807 3NKVR acetylornithine aminotransferase E METABOLISM Amino acid transport and metabolism ACIAD1286 CDS +1 1287349 1288377 no aruG arginine/ornithine succinyltransferase AII subunit 678 3NJDN Arginine N-succinyltransferase beta subunit E METABOLISM Amino acid transport and metabolism ACIAD1287 CDS +3 1288380 1289849 no aruD succinylglutamic semialdehyde dehydrogenase 961 3NISM Catalyzes the NAD-dependent reduction of succinylglutamate semialdehyde into succinylglutamate C METABOLISM Energy production and conversion ACIAD1288 CDS +1 1289875 1291215 no aruB succinylarginine dihydrolase 881 3NKQD Catalyzes the hydrolysis of N(2)-succinylarginine into N(2)-succinylornithine, ammonia and CO(2) E METABOLISM Amino acid transport and metabolism ACIAD1289 CDS +1 1291234 1292211 no aruE succinylglutamate desuccinylase 652 3NK6H Belongs to the AspA AstE family. Succinylglutamate desuccinylase subfamily E METABOLISM Amino acid transport and metabolism ACIAD1290 CDS -3 1292517 1293689 no hypothetical protein; putative signal peptide 817 3NM0Q hemolysin activation secretion protein U CELLULAR PROCESSES AND SIGNALING Intracellular trafficking, secretion, and vesicular transport ACIAD1292 CDS -2 1293793 1294353 no conserved hypothetical protein 386 1S2ZI Phosphohydrolase S POORLY CHARACTERIZED Function unknown ACIAD1293 CDS +3 1294680 1295432 no putative aldolase 516 3NKTR Class II Aldolase and Adducin N-terminal domain G METABOLISM Carbohydrate transport and metabolism ACIAD1294 CDS -3 1295436 1296323 no putative transcriptional regulator (GbuR) 595 3NTAV LysR substrate binding domain K INFORMATION STORAGE AND PROCESSING Transcription ACIAD1295 CDS +2 1296833 1297693 no putative isomerase 594 1S04R Xylose isomerase G METABOLISM Carbohydrate transport and metabolism ACIAD1296 CDS +2 1297694 1298770 no putative oxidoreductase 721 3NKM0 Belongs to the iron ascorbate-dependent oxidoreductase family C METABOLISM Energy production and conversion ACIAD1297 CDS +3 1298781 1299584 no putative amino acid transporter (ABC superfamily, peri_bind) 516 3NM72 Belongs to the bacterial solute-binding protein 3 family E METABOLISM Amino acid transport and metabolism ACIAD1297 CDS +3 1298781 1299584 no putative amino acid transporter (ABC superfamily, peri_bind) 516 3NM72 Belongs to the bacterial solute-binding protein 3 family T CELLULAR PROCESSES AND SIGNALING Signal transduction mechanisms ACIAD1298 CDS +1 1299607 1301136 no putative amino acid transporter (ABC superfamily, atp_bind and membrane) 978 3NMG7 Transporter P METABOLISM Inorganic ion transport and metabolism ACIAD1299 CDS +3 1301544 1302503 no gbuA guanidinobutyrase 648 3NKJ1 Arginase family E METABOLISM Amino acid transport and metabolism ACIAD1300 CDS +1 1302679 1303695 no putative transcriptional regulator 679 3NM34 Evidence 3 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology K INFORMATION STORAGE AND PROCESSING Transcription ACIAD1301 CDS +2 1303769 1304728 no putative glycerate dehydrogenase 648 3NM6Z Evidence 3 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology C METABOLISM Energy production and conversion ACIAD1302 CDS -2 1304887 1305624 no trmB tRNA(guanine-7)methyltransferase 507 3NJ1J Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA J INFORMATION STORAGE AND PROCESSING Translation, ribosomal structure and biogenesis ACIAD1303 CDS +3 1305798 1308221 no putative extracellular nuclease 1587 3NK6V Lamin Tail Domain Q METABOLISM Secondary metabolites biosynthesis, transport and catabolism ACIAD1305 CDS +3 1308423 1309034 no putative glutathionine S-transferase 414 3NJ0K Belongs to the GST superfamily O CELLULAR PROCESSES AND SIGNALING Posttranslational modification, protein turnover, chaperones ACIAD1306 CDS -1 1309076 1309765 no conserved hypothetical protein; putative signal peptide 455 3NT84 S POORLY CHARACTERIZED Function unknown ACIAD1308 CDS -3 1309845 1310630 no thiG thiamine biosynthesis protein, thiazole moiety 505 3NIEW Catalyzes the rearrangement of 1-deoxy-D-xylulose 5- phosphate (DXP) to produce the thiazole phosphate moiety of thiamine. Sulfur is provided by the thiocarboxylate moiety of the carrier protein ThiS. In vitro, sulfur can be provided by H(2)S H METABOLISM Coenzyme transport and metabolism ACIAD1309 CDS -2 1310644 1310841 no thiS C-terminally thiocarboxylated form is intermediate sulfur donor in thiazole formation; part of ThiF/ThiS complex; complexes with ThiG also 130 3NPTY ThiS family H METABOLISM Coenzyme transport and metabolism ACIAD1310 CDS -2 1310854 1311219 no conserved hypothetical protein; putative membrane protein 238 3NNH7 Protein of unknown function (DUF423) S POORLY CHARACTERIZED Function unknown ACIAD1311 CDS -3 1311342 1312211 no rpoH sigma H (sigma 32) factor of RNA polymerase 555 3NJ2U RNA polymerase sigma factor RpoH K INFORMATION STORAGE AND PROCESSING Transcription ACIAD1312 CDS -1 1312343 1312591 no conserved hypothetical protein 171 3NPVG Belongs to the sulfur carrier protein TusA family O CELLULAR PROCESSES AND SIGNALING Posttranslational modification, protein turnover, chaperones ACIAD1313 CDS +1 1312963 1313175 no putative cold shock protein (CspA-like) 147 3NPC2 'Cold-shock' DNA-binding domain K INFORMATION STORAGE AND PROCESSING Transcription ACIAD1314 CDS +3 1313277 1314428 no rhlB ATP-dependent RNA helicase (DEAD box) 755 3NIY4 DEAD-box RNA helicase involved in RNA degradation. Has RNA-dependent ATPase activity and unwinds double-stranded RNA J INFORMATION STORAGE AND PROCESSING Translation, ribosomal structure and biogenesis ACIAD1314 CDS +3 1313277 1314428 no rhlB ATP-dependent RNA helicase (DEAD box) 755 3NIY4 DEAD-box RNA helicase involved in RNA degradation. Has RNA-dependent ATPase activity and unwinds double-stranded RNA K INFORMATION STORAGE AND PROCESSING Transcription ACIAD1314 CDS +3 1313277 1314428 no rhlB ATP-dependent RNA helicase (DEAD box) 755 3NIY4 DEAD-box RNA helicase involved in RNA degradation. Has RNA-dependent ATPase activity and unwinds double-stranded RNA L INFORMATION STORAGE AND PROCESSING Replication, recombination and repair ACIAD1315 CDS -1 1314494 1314817 no conserved hypothetical protein; putative signal peptide 211 3NNX4 S POORLY CHARACTERIZED Function unknown ACIAD1316 CDS +2 1315070 1315654 no putative nitroreductase 385 3NJP3 Nitroreductase family C METABOLISM Energy production and conversion ACIAD1317 CDS +2 1315685 1316758 no gpsA glycerol-3-phosphate dehydrogenase, biosynthetic 695 3NJCE Glycerol-3-phosphate dehydrogenase I METABOLISM Lipid transport and metabolism ACIAD1318 CDS +1 1316815 1317270 no putative phosphohistidine phosphatase 306 3NN5B phosphohistidine phosphatase T CELLULAR PROCESSES AND SIGNALING Signal transduction mechanisms ACIAD1319 CDS +2 1317299 1318438 no putative general secretion pathway protein L (GspL family) 742 3NIFQ Involved in a type II secretion system (T2SS, formerly general secretion pathway, GSP) for the export of proteins U CELLULAR PROCESSES AND SIGNALING Intracellular trafficking, secretion, and vesicular transport ACIAD1320 CDS +1 1318438 1318920 no conserved hypothetical protein 298 3NJKY Type II secretion system (T2SS), protein M S POORLY CHARACTERIZED Function unknown ACIAD1321 CDS +2 1319012 1320016 no pyrD dihydroorotate oxydase 660 3NIRQ Catalyzes the conversion of dihydroorotate to orotate with quinone as electron acceptor F METABOLISM Nucleotide transport and metabolism ACIAD1322 CDS +2 1320077 1320607 no putative membrane protein required for colicin V production (CvpA) 334 3NJ5J membrane protein, required for colicin V production S POORLY CHARACTERIZED Function unknown ACIAD1323 CDS +2 1320632 1322170 no purF amidophosphoribosyltransferase 1013 3NJRY Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine F METABOLISM Nucleotide transport and metabolism ACIAD1324 CDS +2 1322246 1324141 no conserved hypothetical protein; putative membrane protein 1222 3NJYQ Peptidase family M48 O CELLULAR PROCESSES AND SIGNALING Posttranslational modification, protein turnover, chaperones ACIAD1326 CDS +1 1324267 1324881 no conserved hypothetical protein 394 3NM2E S POORLY CHARACTERIZED Function unknown ACIAD1327 CDS +2 1324892 1325857 no tkrA Glyoxylate reductase / Glyoxylatereductase / Hydroxypyruvate reductase , 2-ketoaldonate reductase, broad specificity 626 3NJWE Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family C METABOLISM Energy production and conversion ACIAD1327 CDS +2 1324892 1325857 no tkrA Glyoxylate reductase / Glyoxylatereductase / Hydroxypyruvate reductase , 2-ketoaldonate reductase, broad specificity 626 3NJWE Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family H METABOLISM Coenzyme transport and metabolism ACIAD1328 CDS +1 1325989 1327434 no conserved hypothetical protein; putative signal peptide 931 3NJ4F Functions as both a chaperone and a metalloprotease. Maintains the integrity of the outer membrane by promoting either the assembly or the elimination of outer membrane proteins, depending on their folding state S POORLY CHARACTERIZED Function unknown ACIAD1329 CDS +2 1327526 1327876 no hypothetical protein; putative signal peptide 217 3NPEN S POORLY CHARACTERIZED Function unknown ACIAD1330 CDS -1 1327925 1328368 no conserved hypothetical protein 261 3NN5E Yqey-like protein S POORLY CHARACTERIZED Function unknown ACIAD1331 CDS -3 1328406 1328621 no rpsU 30S ribosomal protein S21 129 3NPA3 Belongs to the bacterial ribosomal protein bS21 family J INFORMATION STORAGE AND PROCESSING Translation, ribosomal structure and biogenesis ACIAD1332 CDS +1 1328767 1329789 no tsaD tRNA N6-adenosine threonylcarbamoyltransferase 668 3NJHB Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction O CELLULAR PROCESSES AND SIGNALING Posttranslational modification, protein turnover, chaperones ACIAD1333 CDS -2 1329838 1331010 no conserved hypothetical protein 803 3NJAR S POORLY CHARACTERIZED Function unknown ACIAD1334 CDS -1 1331117 1332007 no putative ATP/GTP-binding protein 589 3NIJ9 Protein of unknown function (DUF815) S POORLY CHARACTERIZED Function unknown ACIAD1335 CDS +1 1332175 1333680 no putative hydrolase 1000 3NKF8 Domain of unknown function (DUF3336) S POORLY CHARACTERIZED Function unknown ACIAD1336 CDS +1 1333684 1334478 no putative kinase 531 3NNGX Protein tyrosine kinase K INFORMATION STORAGE AND PROCESSING Transcription ACIAD1336 CDS +1 1333684 1334478 no putative kinase 531 3NNGX Protein tyrosine kinase L INFORMATION STORAGE AND PROCESSING Replication, recombination and repair ACIAD1336 CDS +1 1333684 1334478 no putative kinase 531 3NNGX Protein tyrosine kinase T CELLULAR PROCESSES AND SIGNALING Signal transduction mechanisms ACIAD1339 CDS +2 1335452 1336750 no aspY L- and D-aspartate transporter 794 3NKSJ Belongs to the dicarboxylate amino acid cation symporter (DAACS) (TC 2.A.23) family U CELLULAR PROCESSES AND SIGNALING Intracellular trafficking, secretion, and vesicular transport ACIAD1340 CDS +1 1336915 1337115 no conserved hypothetical protein; putative signal peptide 72.8 3NPSN S POORLY CHARACTERIZED Function unknown ACIAD1341 CDS -1 1337129 1337593 no conserved hypothetical protein 288 3NP28 Protein of unknown function (DUF2726) S POORLY CHARACTERIZED Function unknown ACIAD1343 CDS +2 1338008 1339384 no aroP aromatic amino acid transporter (APC family) 882 3NJHM Amino acid permease E METABOLISM Amino acid transport and metabolism ACIAD1344 CDS +3 1339416 1339907 no putative transcriptional regulator 318 3NKM4 Lrp/AsnC ligand binding domain K INFORMATION STORAGE AND PROCESSING Transcription ACIAD1345 CDS +1 1339900 1340526 no conserved hypothetical protein; putative membrane protein 387 3NKST Uncharacterised 5xTM membrane BCR, YitT family COG1284 S POORLY CHARACTERIZED Function unknown ACIAD1346 CDS -3 1340970 1341596 no sodB superoxide dismutase [Fe] 427 3NIKT Destroys radicals which are normally produced within the cells and which are toxic to biological systems P METABOLISM Inorganic ion transport and metabolism ACIAD1347 CDS -1 1341803 1342561 no conserved hypothetical protein 516 3NM4Y NIF3 (NGG1p interacting factor 3) S POORLY CHARACTERIZED Function unknown ACIAD1348 CDS +1 1342738 1343916 no algW HtrA-like serine protease 750 3NJ2S COG0265 Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain O CELLULAR PROCESSES AND SIGNALING Posttranslational modification, protein turnover, chaperones ACIAD1349 CDS -1 1344050 1344658 no conserved hypothetical protein; putative membrane protein 382 3NKGK Protein of unknown function (DUF1449) S POORLY CHARACTERIZED Function unknown ACIAD1350 CDS -2 1344673 1344981 no conserved hypothetical protein; putative iron-sulfur cluster-binding protein, Rieske family 217 3NNYY Rieske [2Fe-2S] domain P METABOLISM Inorganic ion transport and metabolism ACIAD1351 CDS -1 1344998 1346002 no putative sugar kinase protein 637 3NKYT pfkB family carbohydrate kinase G METABOLISM Carbohydrate transport and metabolism ACIAD1353 CDS +1 1346311 1349250 no putative metalloprotease 1934 3NJ0C Peptidase M16C associated S POORLY CHARACTERIZED Function unknown ACIAD1354 CDS +3 1349277 1350437 no putative phospholipase A1 precursor (PldA) 794 3NJDC Phospholipase M CELLULAR PROCESSES AND SIGNALING Cell wall/membrane/envelope biogenesis ACIAD1355 CDS -3 1350489 1351826 no putative potassium uptake protein (TrkH) 830 3NKG3 potassium uptake protein, TrkH P METABOLISM Inorganic ion transport and metabolism ACIAD1356 CDS -2 1351807 1352478 no putative potassium uptake protein 443 3NKMB TrkA-N domain P METABOLISM Inorganic ion transport and metabolism ACIAD1357 CDS -1 1352630 1354168 no ilvA Threonine dehydratase biosynthetic (Threonine deaminase) 1008 3NJ5D Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA E METABOLISM Amino acid transport and metabolism ACIAD1358 CDS +2 1354274 1354945 no rpiA ribose 5-phosphate isomerase 428 3NIM2 Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate G METABOLISM Carbohydrate transport and metabolism ACIAD1359 CDS +1 1354945 1355619 no conserved hypothetical protein 459 3NME1 Protein of unknown function DUF45 S POORLY CHARACTERIZED Function unknown ACIAD1360 CDS +3 1355781 1356830 no argC N-acetyl-gamma-glutamyl-phosphate reductase 689 3NJA9 Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde E METABOLISM Amino acid transport and metabolism ACIAD1361 CDS +2 1356926 1357660 no conserved hypothetical protein 473 3NJH6 S POORLY CHARACTERIZED Function unknown ACIAD1362 CDS +2 1357679 1358092 no clpS substrate modulator for ClpAP, directs protease activity towards aggregated proteins 282 3NN6I Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation S POORLY CHARACTERIZED Function unknown ACIAD1363 CDS +2 1358102 1360378 no clpA ATP-binding protease component 1458 3NK7W ATP-dependent Clp protease ATP-binding subunit O CELLULAR PROCESSES AND SIGNALING Posttranslational modification, protein turnover, chaperones ACIAD1364 CDS +2 1360436 1360741 no conserved hypothetical protein; putative membrane protein 206 3NNM1 Uncharacterised BCR, YnfA/UPF0060 family S POORLY CHARACTERIZED Function unknown ACIAD1365 CDS -2 1360744 1361643 no putative hydrolase 621 3NMKY alpha/beta hydrolase fold I METABOLISM Lipid transport and metabolism ACIAD1366 CDS -2 1361806 1362726 no argF ornithine carbamoyltransferase 611 3NIKC Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline E METABOLISM Amino acid transport and metabolism ACIAD1367 CDS -1 1362827 1363483 no putative transcriptional regulator 446 3NK38 Bacterial regulatory proteins, tetR family K INFORMATION STORAGE AND PROCESSING Transcription ACIAD1368 CDS -1 1363631 1365106 no glnG response regulator in two-component regulatory system with GlnL, nitrogen regulation (EBP family) 969 3NJ88 response regulator T CELLULAR PROCESSES AND SIGNALING Signal transduction mechanisms ACIAD1369 CDS -3 1365093 1366202 no glnL sensory kinase (soluble) in two-component regulatory system 726 3NIW5 PAS domain T CELLULAR PROCESSES AND SIGNALING Signal transduction mechanisms ACIAD1371 CDS +3 1366542 1367885 no rimO Ribosomal protein S12 methylthiotransferases 894 3NIP5 Catalyzes the methylthiolation of an aspartic acid residue of ribosomal protein S12 J INFORMATION STORAGE AND PROCESSING Translation, ribosomal structure and biogenesis ACIAD1372 CDS +1 1367938 1368666 no pyrH uridylate kinase 473 3NK7K Catalyzes the reversible phosphorylation of UMP to UDP F METABOLISM Nucleotide transport and metabolism ACIAD1373 CDS +2 1368746 1369300 no frr ribosome releasing factor 339 3NK5V Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another J INFORMATION STORAGE AND PROCESSING Translation, ribosomal structure and biogenesis ACIAD1374 CDS +3 1369305 1370054 no ispU undecaprenyl pyrophosphate synthetase (di-trans,poly-cis-decaprenylcistransferase) 501 3NIW6 Catalyzes the sequential condensation of isopentenyl diphosphate (IPP) with (2E,6E)-farnesyl diphosphate (E,E-FPP) to yield (2Z,6Z,10Z,14Z,18Z,22Z,26Z,30Z,34E,38E)-undecaprenyl diphosphate (di-trans,octa-cis-UPP). UPP is the precursor of glycosyl carrier lipid in the biosynthesis of bacterial cell wall polysaccharide components such as peptidoglycan and lipopolysaccharide H METABOLISM Coenzyme transport and metabolism ACIAD1375 CDS +2 1370057 1370881 no cdsA phosphatidate cytidylyltransferase 521 3NJWT Belongs to the CDS family I METABOLISM Lipid transport and metabolism ACIAD1376 CDS +2 1370882 1372078 no dxr 1-deoxy-d-xylulose 5-phosphate reductoisomerase 763 3NJ57 Catalyzes the NADP-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate (MEP) I METABOLISM Lipid transport and metabolism ACIAD1377 CDS +3 1372083 1373438 no putative membrane-associated Zn-dependent proteases 1 877 3NJ00 zinc metalloprotease M CELLULAR PROCESSES AND SIGNALING Cell wall/membrane/envelope biogenesis ACIAD1378 CDS +1 1373479 1375956 no putative outer membrane protein 1627 3NJMK Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane M CELLULAR PROCESSES AND SIGNALING Cell wall/membrane/envelope biogenesis ACIAD1379 CDS +1 1376005 1376505 no putative outer membrane protein (OmpH) 300 3NJVP Outer membrane protein (OmpH-like) M CELLULAR PROCESSES AND SIGNALING Cell wall/membrane/envelope biogenesis ACIAD1380 CDS +1 1376509 1377579 no lpxD UDP-3-O-[3-hydroxylauroyl] glucosamine N-acyltransferase 546 3NJ49 Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell M CELLULAR PROCESSES AND SIGNALING Cell wall/membrane/envelope biogenesis ACIAD1381 CDS +1 1377583 1378071 no fabZ (3R)-hydroxymyristoyl-[acyl carrier protein] dehydratase 322 3NJ29 Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs I METABOLISM Lipid transport and metabolism ACIAD1382 CDS +3 1378068 1378856 no lpxA UDP-acetylglucosamine acyltransferase 361 3NJGX Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell M CELLULAR PROCESSES AND SIGNALING Cell wall/membrane/envelope biogenesis ACIAD1383 CDS -1 1378916 1379743 no conserved hypothetical protein; putative signal peptide 383 3NK6Y TolA binding protein trimerisation D CELLULAR PROCESSES AND SIGNALING Cell cycle control, cell division, chromosome partitioning ACIAD1384 CDS -1 1380155 1380634 no recX regulatory protein 299 3NK97 Regulatory protein recX S POORLY CHARACTERIZED Function unknown ACIAD1385 CDS -1 1380692 1381741 no recA DNA strand exchange and recombination protein with protease and nuclease activity. 668 3NIMT Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage L INFORMATION STORAGE AND PROCESSING Replication, recombination and repair ACIAD1386 CDS -3 1381899 1382342 no hslR heat shock protein 15 288 3NN87 Belongs to the HSP15 family J INFORMATION STORAGE AND PROCESSING Translation, ribosomal structure and biogenesis ACIAD1387 CDS +3 1382955 1383815 no cysQ PAPS (adenosine 3'-phosphate 5'-phosphosulfate) 3'(2'),5'-bisphosphate nucleotidase, converts PAPS to APS 582 3NM1A Inositol monophosphatase family P METABOLISM Inorganic ion transport and metabolism ACIAD1388 CDS +2 1383917 1384606 no conserved hypothetical protein 465 3NK78 Histidine phosphatase superfamily (branch 1) G METABOLISM Carbohydrate transport and metabolism ACIAD1389 CDS -1 1384664 1384933 no rpsT 30S ribosomal protein S20 161 3NNXB Binds directly to 16S ribosomal RNA J INFORMATION STORAGE AND PROCESSING Translation, ribosomal structure and biogenesis ACIAD1390 CDS +1 1385143 1385805 no conserved hypothetical protein 421 3NKKX Nucleoside-diphosphate-sugar epimerases G METABOLISM Carbohydrate transport and metabolism ACIAD1390 CDS +1 1385143 1385805 no conserved hypothetical protein 421 3NKKX Nucleoside-diphosphate-sugar epimerases M CELLULAR PROCESSES AND SIGNALING Cell wall/membrane/envelope biogenesis ACIAD1391 CDS +1 1385821 1386333 no rraA Regulator of ribonuclease activity 342 3NJ8F Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions H METABOLISM Coenzyme transport and metabolism ACIAD1392 CDS +2 1386362 1387144 no conserved hypothetical protein 532 3NJW3 Glutathione S-transferase, N-terminal domain O CELLULAR PROCESSES AND SIGNALING Posttranslational modification, protein turnover, chaperones ACIAD1393 CDS +3 1387290 1388231 no conserved hypothetical protein; putative iron-dependent peroxidase 637 3NT7B Dyp-type peroxidase family P METABOLISM Inorganic ion transport and metabolism ACIAD1394 CDS +2 1388270 1388626 no conserved hypothetical protein 234 3NNH8 S POORLY CHARACTERIZED Function unknown ACIAD1395 CDS +2 1388642 1392157 no mfd transcription-repair coupling protein 2284 3NJUH Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site L INFORMATION STORAGE AND PROCESSING Replication, recombination and repair ACIAD1396 CDS +2 1392383 1392808 no conserved hypothetical protein 298 3NIYJ HIT domain F METABOLISM Nucleotide transport and metabolism ACIAD1396 CDS +2 1392383 1392808 no conserved hypothetical protein 298 3NIYJ HIT domain G METABOLISM Carbohydrate transport and metabolism ACIAD1397 CDS +2 1392866 1394323 no putative adenylate or guanylate cyclase 930 3NJJW Adenylyl- / guanylyl cyclase, catalytic domain T CELLULAR PROCESSES AND SIGNALING Signal transduction mechanisms ACIAD1398 CDS -1 1394372 1394710 no fdx [2FE-2S] ferredoxin, electron carrer protein, believed to be involved in assembly of Fe-S clusters 232 3NNH5 Ferredoxin, 2Fe-2S type, ISC system C METABOLISM Energy production and conversion ACIAD1399 CDS -2 1394725 1396587 no hscA heat shock protein (Hsp); chaperon involved in the Fe/S cluster biosynthesis 1186 3NJWI Chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Has a low intrinsic ATPase activity which is markedly stimulated by HscB O CELLULAR PROCESSES AND SIGNALING Posttranslational modification, protein turnover, chaperones ACIAD1400 CDS -2 1396621 1397136 no hscB co-chaperone protein (Hsc20), believed to be involved in assembly of Fe-S clusters 328 3NKNS Co-chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Seems to help targeting proteins to be folded toward HscA O CELLULAR PROCESSES AND SIGNALING Posttranslational modification, protein turnover, chaperones ACIAD1402 CDS -2 1397221 1397541 no iscA iron-binding protein , believed to be involved in Fe-S protein formation or repair 223 3NNI0 Is able to transfer iron-sulfur clusters to apo- ferredoxin. Multiple cycles of 2Fe2S cluster formation and transfer are observed, suggesting that IscA acts catalytically. Recruits intracellular free iron so as to provide iron for the assembly of transient iron-sulfur cluster in IscU in the presence of IscS, L-cysteine and the thioredoxin reductase system C METABOLISM Energy production and conversion ACIAD1403 CDS -1 1397567 1397953 no iscU iron-binding protein believed to be involved in Fe-S protein formation or repair; function as a scaffold for the assembly of the transiently bound Fe/S cluster 256 3NN35 A scaffold on which IscS assembles Fe-S clusters. It is likely that Fe-S cluster coordination is flexible as the role of this complex is to build and then hand off Fe-S clusters C METABOLISM Energy production and conversion ACIAD1404 CDS -2 1398025 1399242 no iscS cysteine desulfurase used in synthesis of Fe-S cluster (tRNA 4-thiouridine sulfurtransferase ) 796 3NKJK Master enzyme that delivers sulfur to a number of partners involved in Fe-S cluster assembly, tRNA modification or cofactor biosynthesis. Catalyzes the removal of elemental sulfur atoms from cysteine to produce alanine. Functions as a sulfur delivery protein for Fe-S cluster synthesis onto IscU, an Fe-S scaffold assembly protein, as well as other S acceptor proteins E METABOLISM Amino acid transport and metabolism ACIAD1405 CDS -1 1399244 1399687 no iscR repressor of the iscRSUA operon, involved in assembly of Fe-S clusters 284 3NJTK Transcriptional regulator K INFORMATION STORAGE AND PROCESSING Transcription ACIAD1406 CDS -3 1399827 1400480 no conserved hypothetical protein; putative membrane protein 409 3NK14 S POORLY CHARACTERIZED Function unknown ACIAD1407 CDS +2 1400621 1401133 no putative poly(hydroxyalcanoate) granule associated protein 271 3NNGS Poly(hydroxyalcanoate) granule associated protein (phasin) S POORLY CHARACTERIZED Function unknown ACIAD1408 CDS +3 1401297 1401569 no hupB DNA-binding protein HU-beta 169 3NNVG Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions L INFORMATION STORAGE AND PROCESSING Replication, recombination and repair ACIAD1409 CDS +3 1401702 1403570 no ppiD peptidyl-prolyl cis-trans isomerase precursor (PPIase) (Rotamase) 1168 3NM2T Peptidylprolyl isomerase O CELLULAR PROCESSES AND SIGNALING Posttranslational modification, protein turnover, chaperones ACIAD1410 CDS -2 1403617 1404537 no alkR transcriptional regulator (XylS/AraC family) 611 3NM1G Cupin K INFORMATION STORAGE AND PROCESSING Transcription ACIAD1411 CDS +1 1404733 1405959 no alkM terminal alkane-1-monooxygenase 830 3NJ6G Fatty acid desaturase P METABOLISM Inorganic ion transport and metabolism ACIAD1412 CDS -3 1406016 1407221 no acadm medium-chain acyl-CoA dehydrogenase 781 3NIU3 Acyl-CoA dehydrogenase, C-terminal domain I METABOLISM Lipid transport and metabolism ACIAD1413 CDS -2 1407253 1408557 no putative acyl-CoA dehydrogenase 846 3NJV5 Acyl-CoA dehydrogenase, C-terminal domain I METABOLISM Lipid transport and metabolism ACIAD1414 CDS -1 1408763 1410163 no conserved hypothetical protein 909 3NJ7W ABC1 family S POORLY CHARACTERIZED Function unknown ACIAD1415 CDS -2 1410433 1410741 no conserved hypothetical protein 207 3NPBK S POORLY CHARACTERIZED Function unknown ACIAD1416 CDS +3 1410909 1411265 no conserved hypothetical protein; putative membrane protein 227 3NNHC Protein of unknown function (DUF1304) S POORLY CHARACTERIZED Function unknown ACIAD1417 CDS -1 1411352 1412692 no arcD arginine/ornithine antiporter 835 3NIQT Amino acid permease E METABOLISM Amino acid transport and metabolism ACIAD1418 CDS -2 1412698 1413576 no putative homocysteine S-methyltransferase family protein 587 3NKZM Homocysteine S-methyltransferase H METABOLISM Coenzyme transport and metabolism ACIAD1419 CDS -1 1413752 1415086 no putative dihydroorotase 900 3NMEC Amidohydrolase family F METABOLISM Nucleotide transport and metabolism ACIAD1420 CDS -3 1415091 1415651 no conserved hypothetical protein; putative carbonate dehydratase 378 3NK3U Bacterial transferase hexapeptide (six repeats) S POORLY CHARACTERIZED Function unknown ACIAD1421 CDS -3 1415826 1417133 no putative histidine kinase of 2-component regulatory system 830 3NM1W His Kinase A (phosphoacceptor) domain T CELLULAR PROCESSES AND SIGNALING Signal transduction mechanisms ACIAD1422 CDS -2 1417204 1417884 no putative 2-component regulatory protein 453 3NMHN Transcriptional regulatory protein, C terminal K INFORMATION STORAGE AND PROCESSING Transcription ACIAD1422 CDS -2 1417204 1417884 no putative 2-component regulatory protein 453 3NMHN Transcriptional regulatory protein, C terminal T CELLULAR PROCESSES AND SIGNALING Signal transduction mechanisms ACIAD1423 CDS -1 1417886 1419538 no eptA lipid A phosphoethanolamine transferase, associated with polymyxin resistance 1083 3NJEC Domain of unknown function (DUF1705) S POORLY CHARACTERIZED Function unknown ACIAD1424 CDS +2 1419854 1421125 no salA salicylate 1-monooxygenase 852 3NKZF FAD binding domain C METABOLISM Energy production and conversion ACIAD1425 CDS +3 1421250 1422140 no salR transcriptional regulator (LysR family) 584 3NT7Q LysR substrate binding domain K INFORMATION STORAGE AND PROCESSING Transcription ACIAD1426 CDS -2 1422172 1422891 no salE salicylate esterase 503 1SD7K Alpha/beta hydrolase family I METABOLISM Lipid transport and metabolism ACIAD1427 CDS -2 1422922 1424088 no putative fatty acid and hydrocarbon transporter (SalD) 780 3NSUN Outer membrane protein transport protein (OMPP1/FadL/TodX) I METABOLISM Lipid transport and metabolism ACIAD1428 CDS -1 1424279 1425259 no areA esterase for aryl ester catabolic pathway 675 3NIV6 Carboxylesterase family I METABOLISM Lipid transport and metabolism ACIAD1429 CDS -2 1425343 1426458 no areB aryl-alcohol dehydrogenase 728 3NM15 Alcohol dehydrogenase GroES-like domain C METABOLISM Energy production and conversion ACIAD1430 CDS -2 1426486 1428006 no areC benzaldehyde dehydrogenase II 991 3NIKA belongs to the aldehyde dehydrogenase family C METABOLISM Energy production and conversion ACIAD1431 CDS -1 1428191 1429993 no areR sigma(54)-dependent transcriptionnal regulator for areCBA operon 1200 3NJDJ Sigma-54 interaction domain K INFORMATION STORAGE AND PROCESSING Transcription ACIAD1431 CDS -1 1428191 1429993 no areR sigma(54)-dependent transcriptionnal regulator for areCBA operon 1200 3NJDJ Sigma-54 interaction domain Q METABOLISM Secondary metabolites biosynthesis, transport and catabolism ACIAD1433 CDS +3 1430277 1431524 no putative porin for benzoate transport (BenP) 840 3NKRU outer membrane porin, OprD family S POORLY CHARACTERIZED Function unknown ACIAD1434 CDS +1 1431562 1432962 no benK benzoate transport protein (MFS superfamily) 885 3NKTE Uncharacterised MFS-type transporter YbfB E METABOLISM Amino acid transport and metabolism ACIAD1434 CDS +1 1431562 1432962 no benK benzoate transport protein (MFS superfamily) 885 3NKTE Uncharacterised MFS-type transporter YbfB G METABOLISM Carbohydrate transport and metabolism ACIAD1434 CDS +1 1431562 1432962 no benK benzoate transport protein (MFS superfamily) 885 3NKTE Uncharacterised MFS-type transporter YbfB P METABOLISM Inorganic ion transport and metabolism ACIAD1435 CDS -1 1433015 1433929 no benR transcriptional regulator of benzoate degradation (LysR family) 600 3NJTH Transcriptional regulator K INFORMATION STORAGE AND PROCESSING Transcription ACIAD1436 CDS +1 1434223 1435608 no benA benzoate 1,2-dioxygenase alpha subunit 966 3NJXU Ring hydroxylating alpha subunit (catalytic domain) P METABOLISM Inorganic ion transport and metabolism ACIAD1437 CDS +3 1435605 1436114 no benB benzoate 1,2-dioxygenase beta subunit 345 3NK17 Ring hydroxylating beta subunit Q METABOLISM Secondary metabolites biosynthesis, transport and catabolism ACIAD1438 CDS +3 1436157 1437203 no benC benzoate 1,2-dioxygenase electron transfer component [Includes: Ferredoxin; Ferredoxin--NAD(+) reductase] 715 3NIM5 Oxidoreductase FAD-binding domain C METABOLISM Energy production and conversion ACIAD1439 CDS +3 1437222 1438007 no benD cis-1,2-dihydroxycyclohexa-3,5-diene-1-carboxylate dehydrogenase,(cis-1,2-dihydroxy-3,4-cyclohexadiene-1-carboxylate dehydrogenase) (2-hydro-1,2-dihydroxybenzoate dehydrogenase) (DHB dehydrogenase) 503 3NM5U Enoyl-(Acyl carrier protein) reductase I METABOLISM Lipid transport and metabolism ACIAD1439 CDS +3 1437222 1438007 no benD cis-1,2-dihydroxycyclohexa-3,5-diene-1-carboxylate dehydrogenase,(cis-1,2-dihydroxy-3,4-cyclohexadiene-1-carboxylate dehydrogenase) (2-hydro-1,2-dihydroxybenzoate dehydrogenase) (DHB dehydrogenase) 503 3NM5U Enoyl-(Acyl carrier protein) reductase Q METABOLISM Secondary metabolites biosynthesis, transport and catabolism ACIAD1440 CDS +2 1438034 1439233 no benE benzoate membrane transport protein MFS superfamily) 758 3NKBX Benzoate membrane transport protein Q METABOLISM Secondary metabolites biosynthesis, transport and catabolism ACIAD1442 CDS +1 1439848 1440783 no catA catechol 1,2-dioxygenase 642 3NJ2W Catechol dioxygenase N terminus Q METABOLISM Secondary metabolites biosynthesis, transport and catabolism ACIAD1443 CDS +1 1440793 1442127 no conserved hypothetical protein; putative GTP-binding protein 855 3NMV9 50S ribosome-binding GTPase S POORLY CHARACTERIZED Function unknown ACIAD1444 CDS +3 1442076 1443653 no conserved hypothetical protein; putative GTP-binding protein 990 3NMNR Dynamin family S POORLY CHARACTERIZED Function unknown ACIAD1445 CDS -1 1443680 1444591 no catM HTH-type transcriptional regulator catM (Cat operon transcriptional regulator) (LysR family) 590 3NJTH Transcriptional regulator K INFORMATION STORAGE AND PROCESSING Transcription ACIAD1446 CDS +2 1444715 1445827 no catB muconate cycloisomerase I (Cis,cis-muconate lactonizing enzyme I) (MLE) 717 3NIX4 Mandelate racemase / muconate lactonizing enzyme, C-terminal domain G METABOLISM Carbohydrate transport and metabolism ACIAD1447 CDS +1 1445845 1446135 no catC muconolactone delta-isomerase (MIase) 197 3NNVF Muconolactone delta-isomerase Q METABOLISM Secondary metabolites biosynthesis, transport and catabolism ACIAD1448 CDS +3 1446225 1446911 no catI 3-oxoadipate CoA-transferase subunit A (Beta-ketoadipate:succinyl-CoA transferase subunit A) 448 3NKH5 3-oxoadipate CoA-transferase activity I METABOLISM Lipid transport and metabolism ACIAD1449 CDS +1 1446922 1447575 no catJ 3-oxoadipate CoA-transferase subunit B (Beta-ketoadipate:succinyl-CoA transferase subunit B) 443 3NJPC 3-oxoadipate CoA-transferase activity I METABOLISM Lipid transport and metabolism ACIAD1450 CDS +1 1447588 1448793 no catF beta-ketoadipyl CoA thiolase 764 3NIPS Belongs to the thiolase family I METABOLISM Lipid transport and metabolism ACIAD1451 CDS +1 1448803 1449606 no catD 3-oxoadipate enol-lactonase II (Beta-ketoadipate enol-lactone hydrolase II) 540 3NIX7 Alpha/beta hydrolase family E METABOLISM Amino acid transport and metabolism ACIAD1452 CDS +1 1449889 1451232 no putative aminotransferase 885 3NKVT Aminotransferase class-III E METABOLISM Amino acid transport and metabolism ACIAD1453 CDS -1 1451276 1451692 no putative transcriptional regulator 280 3NNDT HxlR-like helix-turn-helix K INFORMATION STORAGE AND PROCESSING Transcription ACIAD1454 CDS +1 1451791 1452804 no putative Zn-dependent oxidoreductase 661 3NIRI Belongs to the zinc-containing alcohol dehydrogenase family. Quinone oxidoreductase subfamily C METABOLISM Energy production and conversion ACIAD1455 CDS -3 1452858 1453892 no putative transcriptional regulator protein (AraC family) 700 3NJ7F Arabinose-binding domain of AraC transcription regulator, N-term K INFORMATION STORAGE AND PROCESSING Transcription ACIAD1456 CDS -1 1454042 1455352 no conserved hypothetical protein 879 3NJUF Phosphorylcholine phosphatase E METABOLISM Amino acid transport and metabolism ACIAD1457 CDS -2 1455427 1456437 no putative homoserine kinase type II 697 3NKDJ Choline/ethanolamine kinase S POORLY CHARACTERIZED Function unknown ACIAD1458 CDS +3 1456611 1458035 no putative transport protein 892 3NKJN Amino acid permease E METABOLISM Amino acid transport and metabolism ACIAD1459 CDS +3 1458132 1458605 no hypothetical protein; putaive membrane protein 312 3NPN3 S POORLY CHARACTERIZED Function unknown ACIAD1460 CDS +3 1458618 1460753 no putative ferrichrome-iron receptor protein 1426 3NIGR TonB dependent receptor P METABOLISM Inorganic ion transport and metabolism ACIAD1461 CDS -2 1460803 1461711 no conserved hypothetical protein; putative membrane protein 608 3NIGF Bestrophin, RFP-TM, chloride channel S POORLY CHARACTERIZED Function unknown ACIAD1462 CDS -1 1462118 1462867 no putative transcriptional regulator (GntR family) 479 3NIVG FCD K INFORMATION STORAGE AND PROCESSING Transcription ACIAD1463 CDS +1 1463269 1464255 no putative binding protein (ABC superfamily, peri_bind) 662 3NKYB NMT1/THI5 like P METABOLISM Inorganic ion transport and metabolism ACIAD1464 CDS +3 1464282 1465124 no putative transport protein (ABC superfamily, atp_bind) 555 3NJMN ATPases associated with a variety of cellular activities P METABOLISM Inorganic ion transport and metabolism ACIAD1465 CDS +1 1465117 1465911 no putative permease protein (ABC superfamily, membrane) 486 3NJDX Binding-protein-dependent transport system inner membrane component P METABOLISM Inorganic ion transport and metabolism ACIAD1467 CDS +3 1465908 1467347 no putative hydrolase protein 944 3NKU6 Amidohydrolase family F METABOLISM Nucleotide transport and metabolism ACIAD1469 CDS +3 1468041 1468496 no putative RNA polymerase sigma factor (iron regulated) 295 3NINI ECF sigma factor K INFORMATION STORAGE AND PROCESSING Transcription ACIAD1471 CDS +3 1468497 1469513 no putative transmembrane sensor protein (iron transport) 638 3NT7N FecR protein P METABOLISM Inorganic ion transport and metabolism ACIAD1471 CDS +3 1468497 1469513 no putative transmembrane sensor protein (iron transport) 638 3NT7N FecR protein T CELLULAR PROCESSES AND SIGNALING Signal transduction mechanisms ACIAD1472 CDS +1 1469653 1472826 no putative receptor protein 2135 3NK26 Secretin and TonB N terminus short domain P METABOLISM Inorganic ion transport and metabolism ACIAD1473 CDS +1 1473019 1473810 no conserved hypothetical protein; putative signal peptide 483 3NMHI C-lobe and N-lobe beta barrels of Tf-binding protein B S POORLY CHARACTERIZED Function unknown ACIAD1474 CDS +2 1473869 1475380 no conserved hypothetical protein; putative signal peptide 1001 3NIQF Protein of unknown function (DUF560) O CELLULAR PROCESSES AND SIGNALING Posttranslational modification, protein turnover, chaperones ACIAD1477 CDS +3 1475520 1476311 no conserved hypothetical protein; putative TonB-related protein 476 3NKGZ Gram-negative bacterial TonB protein C-terminal M CELLULAR PROCESSES AND SIGNALING Cell wall/membrane/envelope biogenesis ACIAD1478 CDS +2 1476344 1476943 no hemO heme oxygenase 387 3NM6A Heme oxygenase P METABOLISM Inorganic ion transport and metabolism ACIAD1479 CDS +3 1476972 1477415 no conserved hypothetical protein; putative membrane protein 305 3NN36 membrane S POORLY CHARACTERIZED Function unknown ACIAD1480 CDS +3 1477677 1478666 no hypothetical protein 636 3NQ4F Restriction endonuclease S POORLY CHARACTERIZED Function unknown ACIAD1481 CDS -3 1479012 1480433 no cysS cysteinyl-tRNA synthetase 962 3NKQW Belongs to the class-I aminoacyl-tRNA synthetase family J INFORMATION STORAGE AND PROCESSING Translation, ribosomal structure and biogenesis ACIAD1482 CDS +3 1480647 1481624 no kdsD D-arabinose 5-phosphate isomerase 628 3NJ4R Arabinose 5-phosphate isomerase M CELLULAR PROCESSES AND SIGNALING Cell wall/membrane/envelope biogenesis ACIAD1483 CDS +3 1481628 1482167 no kdsC 3-Deoxy-D-manno-octulosonate 8-phosphate (KDO 8-P) phosphatase 357 3NJB4 Involved in the biosynthesis of lipopolysaccharides (LPSs). Catalyzes the hydrolysis of 3-deoxy-D-manno-octulosonate 8-phosphate (KDO 8-P) to 3-deoxy-D-manno-octulosonate (KDO) and inorganic phosphate S POORLY CHARACTERIZED Function unknown ACIAD1484 CDS +2 1482206 1482754 no conserved hypothetical protein 360 3NJS8 Lipopolysaccharide-assembly, LptC-related S POORLY CHARACTERIZED Function unknown ACIAD1485 CDS +3 1482810 1483286 no putative lipopolysaccharide transport protein A (ABC superfamily, peri_bind) (LptA) 299 3NJF1 Involved in the assembly of lipopolysaccharide (LPS). Required for the translocation of LPS from the inner membrane to the outer membrane. May form a bridge between the inner membrane and the outer membrane, via interactions with LptC and LptD, thereby facilitating LPS transfer across the periplasm S POORLY CHARACTERIZED Function unknown ACIAD1486 CDS +2 1483286 1484035 no putative lipopolysaccharide transport protein B (ABC superfamily, atp_bind) (LptB) 481 3NIKP ABC transporter S POORLY CHARACTERIZED Function unknown ACIAD1487 CDS +3 1484367 1485779 no putative outer membrane efflux protein, type I secretion protein 871 3NJQY Outer membrane efflux protein M CELLULAR PROCESSES AND SIGNALING Cell wall/membrane/envelope biogenesis ACIAD1487 CDS +3 1484367 1485779 no putative outer membrane efflux protein, type I secretion protein 871 3NJQY Outer membrane efflux protein U CELLULAR PROCESSES AND SIGNALING Intracellular trafficking, secretion, and vesicular transport ACIAD1488 CDS +2 1485776 1487920 no putative protein secretion efflux system (ABC superfamily, atp_bind and membrane) 1360 3NIH7 ABC transporter transmembrane region V CELLULAR PROCESSES AND SIGNALING Defense mechanisms ACIAD1489 CDS +1 1487917 1489107 no putative protein secretion efflux system, membrane fusion protein (hemolysin-type secretion transmembrane protein) (superfamily ABC, membrane) 743 3NKF2 HlyD membrane-fusion protein of T1SS M CELLULAR PROCESSES AND SIGNALING Cell wall/membrane/envelope biogenesis ACIAD1490 CDS +1 1489207 1489806 no conserved hypothetical protein 399 3NK58 Uncharacterized protein family UPF0029 S POORLY CHARACTERIZED Function unknown ACIAD1491 CDS +2 1489853 1490410 no putative acyltransferase. 390 3NIQ9 Hexapeptide repeat of succinyl-transferase S POORLY CHARACTERIZED Function unknown ACIAD1492 CDS -3 1490463 1491470 no hypothetical protein 534 3NQ2I S POORLY CHARACTERIZED Function unknown ACIAD1493 CDS +2 1491809 1492651 no conserved hypothetical protein; putative universal stress protein 553 3NIEK Belongs to the universal stress protein A family T CELLULAR PROCESSES AND SIGNALING Signal transduction mechanisms ACIAD1495 CDS -2 1492762 1493430 no putative O-methyltransferase protein 442 3NJP4 O-methyltransferase S POORLY CHARACTERIZED Function unknown ACIAD1496 CDS -2 1493584 1494306 no conserved hypothetical protein 503 3NMC5 Peptidase M15 S POORLY CHARACTERIZED Function unknown ACIAD1498 CDS -2 1494433 1494756 no fdxA 7-Fe ferredoxin 236 3NNIM Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions C METABOLISM Energy production and conversion ACIAD1499 CDS -2 1495081 1495530 no BLUF domain protein 309 3NN0H Sensors of blue-light using FAD S POORLY CHARACTERIZED Function unknown ACIAD1500 CDS -1 1495787 1498432 no mutS methyl-directed mismatch repair, recognize exocyclic adducts of guanosine 1709 3NK8D that it carries out the mismatch recognition step. This protein has a weak ATPase activity L INFORMATION STORAGE AND PROCESSING Replication, recombination and repair ACIAD1501 CDS +1 1498660 1498866 no hypothetical protein 77.8 3NJHA Arm DNA-binding domain L INFORMATION STORAGE AND PROCESSING Replication, recombination and repair ACIAD1503 CDS +1 1499227 1500285 no putative desulfurization enzyme B (dibenzothiophene ) 704 3NJNI ABC-type nitrate sulfonate bicarbonate transport P METABOLISM Inorganic ion transport and metabolism ACIAD1504 CDS +2 1500299 1501012 no putative aldolase class II 474 3NMBU Class II Aldolase and Adducin N-terminal domain G METABOLISM Carbohydrate transport and metabolism ACIAD1505 CDS +1 1501045 1502238 no putative Dibenzothiophene desulfurization enzyme 803 3NJ1I Luciferase-like monooxygenase C METABOLISM Energy production and conversion ACIAD1506 CDS +2 1502249 1503823 no putative dipeptide transport protein (ABC superfamily, peri_bind) 1050 3NM5S Bacterial extracellular solute-binding proteins, family 5 Middle E METABOLISM Amino acid transport and metabolism ACIAD1507 CDS +1 1503829 1504980 no putative dipeptide transport protein (ABC superfamily, membrane) 706 3NSY0 Binding-protein-dependent transport system inner membrane component P METABOLISM Inorganic ion transport and metabolism ACIAD1508 CDS +3 1504977 1505825 no putative dipeptide transport protein (ABC superfamily, membrane) 535 3NT1K Binding-protein-dependent transport system inner membrane component P METABOLISM Inorganic ion transport and metabolism ACIAD1509 CDS +2 1505828 1507645 no putative dipeptide transporter (ABC superfamily, ATP_bind) 1161 3NJT5 Oligopeptide/dipeptide transporter, C-terminal region P METABOLISM Inorganic ion transport and metabolism ACIAD1510 CDS +2 1507661 1508941 no putative acyl-CoA dehydrogenase, putative desulfurization enzyme C (dibenzothiophene) 837 3NMCK Acyl-CoA dehydrogenase, C-terminal domain I METABOLISM Lipid transport and metabolism ACIAD1512 CDS -3 1509279 1510331 no putative dibenzothiophene desulfurization enzyme B 699 3NMTZ ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components P METABOLISM Inorganic ion transport and metabolism ACIAD1514 CDS +1 1510570 1512426 no putative transport protein (ABC superfamily, atp_bind and membrane) 1187 3NM2N ABC transporter transmembrane region V CELLULAR PROCESSES AND SIGNALING Defense mechanisms ACIAD1515 CDS +3 1512423 1514255 no putative transport protein (ABC superfamily, atp_bind and membrane) 1173 3NM31 ABC transporter transmembrane region V CELLULAR PROCESSES AND SIGNALING Defense mechanisms ACIAD1516 CDS +1 1514422 1516914 no putative ferric enterobactin receptor protein 1615 3NT05 TonB dependent receptor P METABOLISM Inorganic ion transport and metabolism ACIAD1517 CDS +3 1516956 1518218 no putative exported hydrolase 844 3NSXS Secretory lipase S POORLY CHARACTERIZED Function unknown ACIAD1518 CDS -2 1518310 1519398 no putative alkanesulfonate monooxygenase 730 3NMJA Luciferase-like monooxygenase C METABOLISM Energy production and conversion ACIAD1519 CDS +1 1519714 1520790 no putative sigma-54 dependent transcriptional regulator 698 3NTMK Sigma-54 interaction domain K INFORMATION STORAGE AND PROCESSING Transcription ACIAD1520 CDS -3 1520820 1521566 no tatC Sec-independent protein secretion pathway, component C. 464 3NMEZ Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. Together with TatB, TatC is part of a receptor directly interacting with Tat signal peptides U CELLULAR PROCESSES AND SIGNALING Intracellular trafficking, secretion, and vesicular transport ACIAD1521 CDS -1 1521563 1521979 no tatB Sec-independent protein secretion pathway, component B 248 3NNDP Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes U CELLULAR PROCESSES AND SIGNALING Intracellular trafficking, secretion, and vesicular transport ACIAD1522 CDS -3 1521993 1522208 no tatA Sec-independent protein secretion pathway, translocase protein 134 3NPIY Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system U CELLULAR PROCESSES AND SIGNALING Intracellular trafficking, secretion, and vesicular transport ACIAD1523 CDS -3 1522305 1523060 no putative transport protein (ABC superfamily, ATP_bind) 494 3NKXK ATPases associated with a variety of cellular activities P METABOLISM Inorganic ion transport and metabolism ACIAD1524 CDS -2 1523095 1523883 no putative permease protein (ABC superfamily, membrane) 515 3NKMG Binding-protein-dependent transport system inner membrane component P METABOLISM Inorganic ion transport and metabolism ACIAD1525 CDS -3 1523883 1524722 no putative permease protein (ABC superfamily, membrane) 502 3NKD1 Binding-protein-dependent transport system inner membrane component P METABOLISM Inorganic ion transport and metabolism ACIAD1526 CDS -3 1524726 1525799 no putative binding protein (ABC superfamily, peri_bind) 710 3NM8R NMT1-like family P METABOLISM Inorganic ion transport and metabolism ACIAD1527 CDS +3 1526115 1527242 no putative FMNH2-dependent methane/alkanesulfonate monooxygenase 762 3NM57 Luciferase-like monooxygenase C METABOLISM Energy production and conversion ACIAD1528 CDS +1 1527439 1528266 no putative tonB-like protein 399 3NT4I Gram-negative bacterial TonB protein C-terminal M CELLULAR PROCESSES AND SIGNALING Cell wall/membrane/envelope biogenesis ACIAD1529 CDS +1 1528291 1529025 no putative biopolymer transport protein (ExbB-like) 457 3NTIN MotA/TolQ/ExbB proton channel family U CELLULAR PROCESSES AND SIGNALING Intracellular trafficking, secretion, and vesicular transport ACIAD1530 CDS +3 1529025 1529429 no putative biopolymer transport protein (ExbD-like) 241 3NN64 Biopolymer transport protein ExbD/TolR U CELLULAR PROCESSES AND SIGNALING Intracellular trafficking, secretion, and vesicular transport ACIAD1531 CDS -2 1529494 1531077 no putative oligopeptide binding protein (ABC superfamily, peri_bind)(OppA) 1051 3NKYA Bacterial extracellular solute-binding proteins, family 5 Middle E METABOLISM Amino acid transport and metabolism ACIAD1533 CDS +1 1531363 1533975 no hypothetical protein; putative outer membrane receptor protein 1760 3NMM9 Receptor P METABOLISM Inorganic ion transport and metabolism ACIAD1534 CDS +2 1534223 1536553 no putative tonB-dependent receptor protein (outer membrane salicin receptor) 1556 3NKXW TonB dependent receptor P METABOLISM Inorganic ion transport and metabolism ACIAD1535 CDS +2 1536572 1537765 no putative FMNH2-dependent monooxygenase (sulfonate). 796 3NM0C Luciferase-like monooxygenase C METABOLISM Energy production and conversion ACIAD1536 CDS -1 1537889 1539016 no TcuC Fe-S oxidoreductase 757 3NJME TIGRFAM CitB domain protein C METABOLISM Energy production and conversion ACIAD1537 CDS -3 1539006 1540412 no TcuA tricarballylate dehydrogenase 961 3NJDW FAD dependent oxidoreductase C METABOLISM Energy production and conversion ACIAD1539 CDS -2 1540516 1541445 no TcuR putative transcriptional regulator (LysR family) 588 3NKPJ LysR substrate binding domain K INFORMATION STORAGE AND PROCESSING Transcription ACIAD1540 CDS -3 1541577 1542371 no putative substrate-binding protein (ABC superfamily, peri-bind) 514 3NKI5 Bacterial extracellular solute-binding protein P METABOLISM Inorganic ion transport and metabolism ACIAD1541 CDS -1 1542461 1543771 no citA citrate-proton symporter (MFS superfamily) 843 3NSX0 Sugar (and other) transporter E METABOLISM Amino acid transport and metabolism ACIAD1541 CDS -1 1542461 1543771 no citA citrate-proton symporter (MFS superfamily) 843 3NSX0 Sugar (and other) transporter G METABOLISM Carbohydrate transport and metabolism ACIAD1541 CDS -1 1542461 1543771 no citA citrate-proton symporter (MFS superfamily) 843 3NSX0 Sugar (and other) transporter P METABOLISM Inorganic ion transport and metabolism ACIAD1543 CDS -3 1544040 1544969 no putative transcriptional regulator (LysR family) 593 3NMKS LysR substrate binding domain K INFORMATION STORAGE AND PROCESSING Transcription ACIAD1545 CDS -1 1545290 1545745 no conserved hypothetical protein 323 3NM3H HxlR-like helix-turn-helix K INFORMATION STORAGE AND PROCESSING Transcription ACIAD1547 CDS +3 1545909 1546775 no conserved hypothetical protein 580 3NJQK Predicted metal-dependent hydrolase S POORLY CHARACTERIZED Function unknown ACIAD1548 CDS +3 1546902 1547582 no putative glutathione S-transferase 456 3NM84 Glutathione S-transferase N-terminal domain O CELLULAR PROCESSES AND SIGNALING Posttranslational modification, protein turnover, chaperones ACIAD1549 CDS +2 1547579 1548346 no putative short chain dehydrogenase 499 3NIGV Enoyl-(Acyl carrier protein) reductase I METABOLISM Lipid transport and metabolism ACIAD1549 CDS +2 1547579 1548346 no putative short chain dehydrogenase 499 3NIGV Enoyl-(Acyl carrier protein) reductase Q METABOLISM Secondary metabolites biosynthesis, transport and catabolism ACIAD1550 CDS +3 1548348 1549013 no putative oxidoreductase, short-chain dehydrogenase/reductase family 434 3NKTN Short-chain dehydrogenase reductase Sdr I METABOLISM Lipid transport and metabolism ACIAD1550 CDS +3 1548348 1549013 no putative oxidoreductase, short-chain dehydrogenase/reductase family 434 3NKTN Short-chain dehydrogenase reductase Sdr Q METABOLISM Secondary metabolites biosynthesis, transport and catabolism ACIAD1551 fCDS +2 1549355 1549534 pseudo fragment of transposase (part 1) 73.6 3NNFB Helix-turn-helix of DDE superfamily endonuclease S POORLY CHARACTERIZED Function unknown ACIAD1552 fCDS +1 1549648 1549836 pseudo fragment of transposase (part 2) 65.9 3NNFB Helix-turn-helix of DDE superfamily endonuclease S POORLY CHARACTERIZED Function unknown ACIAD1553 fCDS +3 1549833 1550030 pseudo fragment of transposase (part 3) 79.3 3NTR4 DDE superfamily endonuclease L INFORMATION STORAGE AND PROCESSING Replication, recombination and repair ACIAD1554 CDS +1 1550416 1551429 no putative acyl-CoA dehydrogenase-related protein 682 3NK9D acyl-CoA dehydrogenase I METABOLISM Lipid transport and metabolism ACIAD1556 CDS +3 1551417 1552193 no putative carbohydrate esterase Family 14 LmbE-like 520 3NM25 GlcNAc-PI de-N-acetylase S POORLY CHARACTERIZED Function unknown ACIAD1557 CDS +1 1552186 1552785 no putative methyltransferase 416 3NKR8 Nodulation protein S (NodS) J INFORMATION STORAGE AND PROCESSING Translation, ribosomal structure and biogenesis ACIAD1558 CDS +3 1552782 1553426 no putative glycosyl transferase (GT2 family) 437 3NN7N Glycosyl transferase family 2 M CELLULAR PROCESSES AND SIGNALING Cell wall/membrane/envelope biogenesis ACIAD1559 CDS -1 1553921 1554184 no putative transcriptional regulator (MarR family) 162 3NNRE helix_turn_helix multiple antibiotic resistance protein K INFORMATION STORAGE AND PROCESSING Transcription ACIAD1560 CDS +3 1554216 1554407 partial fragment of P-hydroxyphenylacetate hydroxylase C2:oxygenase component 121 3NJN3 Acyl-CoA dehydrogenase, C-terminal domain I METABOLISM Lipid transport and metabolism ACIAD1561 CDS +3 1554408 1555382 no P-hydroxyphenylacetate hydroxylase C1:reductase component 641 3NIZ4 Flavin reductase like domain S POORLY CHARACTERIZED Function unknown ACIAD1562 CDS +2 1555433 1555711 partial fragment of transposase 83.2 3NNFB Helix-turn-helix of DDE superfamily endonuclease S POORLY CHARACTERIZED Function unknown ACIAD1563 CDS -2 1555825 1555944 partial fragment of transposase 59.7 1XP53 overlaps another CDS with the same product name L INFORMATION STORAGE AND PROCESSING Replication, recombination and repair ACIAD1564 CDS +3 1555992 1556120 partial fragment of transposase 50.8 3NNYR Homeodomain-like domain L INFORMATION STORAGE AND PROCESSING Replication, recombination and repair ACIAD1565 CDS +3 1556547 1557311 no putative 3-hydroxyacyl-CoA dehydrogenase (short-chain) (1.1.1.35/1.1.1.178) 478 3NKSB Belongs to the short-chain dehydrogenases reductases (SDR) family I METABOLISM Lipid transport and metabolism ACIAD1565 CDS +3 1556547 1557311 no putative 3-hydroxyacyl-CoA dehydrogenase (short-chain) (1.1.1.35/1.1.1.178) 478 3NKSB Belongs to the short-chain dehydrogenases reductases (SDR) family Q METABOLISM Secondary metabolites biosynthesis, transport and catabolism ACIAD1566 CDS +2 1557308 1558501 no putative acyl-CoA dehydrogenase family protein 802 3NNAF Acyl-CoA dehydrogenase, C-terminal domain I METABOLISM Lipid transport and metabolism ACIAD1567 CDS +2 1558502 1559569 no conserved hypothetical protein; putative aminoglycoside phosphotransferase. 721 3NKPM Phosphotransferase enzyme family S POORLY CHARACTERIZED Function unknown ACIAD1568 CDS +1 1559560 1560360 no putative enoyl-CoA hydratase/isomerase 494 3NIIF Belongs to the enoyl-CoA hydratase isomerase family I METABOLISM Lipid transport and metabolism ACIAD1569 CDS +3 1560357 1561520 no putative 3-ketoacyl-CoA thiolase/acetyl-CoA acetyltransferase 753 3NIPS Belongs to the thiolase family I METABOLISM Lipid transport and metabolism ACIAD1570 CDS +2 1561511 1562491 no NADH:quinone reductase 637 3NIJ6 Nitronate monooxygenase S POORLY CHARACTERIZED Function unknown ACIAD1571 CDS +1 1562518 1563300 no caiD carnitinyl-CoA dehydratase (Crotonobetainyl-CoA hydratase) 507 3NJXC Enoyl-CoA hydratase/isomerase I METABOLISM Lipid transport and metabolism ACIAD1572 CDS +2 1563341 1564894 no putative acyl-CoA ligase 1043 3NRB6 AMP-binding enzyme C-terminal domain I METABOLISM Lipid transport and metabolism ACIAD1572 CDS +2 1563341 1564894 no putative acyl-CoA ligase 1043 3NRB6 AMP-binding enzyme C-terminal domain Q METABOLISM Secondary metabolites biosynthesis, transport and catabolism ACIAD1574 CDS +2 1565351 1566217 no hypothetical protein 577 1R58D signal Peptide C METABOLISM Energy production and conversion ACIAD1575 CDS +2 1566242 1567483 no linC linalool 8-monooxygenase (Cytochrome P450 111) (Cytochrome P450lin) 832 1SYNI cytochrome p450 C METABOLISM Energy production and conversion ACIAD1576 CDS +3 1567494 1568339 no putative transcriptional regulator (AraC family) 573 1RJPK AraC Family K INFORMATION STORAGE AND PROCESSING Transcription ACIAD1577 CDS +3 1568499 1569962 no putative aldehyde dehydrogenase 961 3NIN2 Involved in the biosynthesis of the osmoprotectant glycine betaine. Catalyzes the reversible oxidation of betaine aldehyde to the corresponding acid C METABOLISM Energy production and conversion ACIAD1578 CDS +2 1569992 1571107 no putative aryl-alcohol dehydrogenase (Benzyl alcohol dehydrogenase) (XylB-like) 736 3NM15 Alcohol dehydrogenase GroES-like domain C METABOLISM Energy production and conversion ACIAD1579 CDS +3 1571127 1571441 no putative ferredoxin (electron transport iron-sulfur protein) 208 COG0633 Ferredoxin C METABOLISM Energy production and conversion ACIAD1579 CDS +3 1571127 1571441 no putative ferredoxin (electron transport iron-sulfur protein) 208 COG0633 Ferredoxin C METABOLISM Energy production and conversion ACIAD1580 CDS +3 1571442 1572683 no putative ferredoxin reductase component (dioxygenase) 833 3NTJP Reductase C-terminal C METABOLISM Energy production and conversion ACIAD1581 CDS -2 1572742 1573359 no putative transcriptional regulator (TetR family) 406 3NQC5 Bacterial regulatory proteins, tetR family K INFORMATION STORAGE AND PROCESSING Transcription ACIAD1582 CDS -3 1573644 1575596 no putative cysteine desulfurase 1 (Csd) 1285 3NMA1 Cys/Met metabolism PLP-dependent enzyme E METABOLISM Amino acid transport and metabolism ACIAD1583 CDS -2 1575571 1576503 no srpI major membrane protein I (MMP-I) (35 kDa antigen) 621 3NIIU - Catabolite gene activator and regulatory subunit of cAMP-dependent protein T CELLULAR PROCESSES AND SIGNALING Signal transduction mechanisms ACIAD1584 CDS -3 1576758 1577684 no srpH serine acetyltransferase 607 3NMA0 Bacterial transferase hexapeptide (six repeats) E METABOLISM Amino acid transport and metabolism ACIAD1585 CDS -1 1577735 1578229 no conserved hypothetical protein; putative rhodanese-related sulfurtransferase 328 3NK6A Rhodanese Homology Domain P METABOLISM Inorganic ion transport and metabolism ACIAD1586 CDS +1 1578607 1580232 no atsB sulfate ester permease protein (ABC superfamily, membrane) 994 3NT1X Binding-protein-dependent transport system inner membrane component P METABOLISM Inorganic ion transport and metabolism ACIAD1587 CDS +1 1580242 1581057 no atsC sulfate ester transporter (ABC superfamily, ATP_bind) 526 3NN0E ATPases associated with a variety of cellular activities P METABOLISM Inorganic ion transport and metabolism ACIAD1588 CDS +1 1581067 1581915 no putative tonB-like protein 463 3NT4J Gram-negative bacterial TonB protein C-terminal M CELLULAR PROCESSES AND SIGNALING Cell wall/membrane/envelope biogenesis ACIAD1589 CDS +1 1581952 1582686 no putative biopolymer transport protein (ExbB-like) 461 3NN1A MotA/TolQ/ExbB proton channel family U CELLULAR PROCESSES AND SIGNALING Intracellular trafficking, secretion, and vesicular transport ACIAD1590 CDS +3 1582686 1583093 no putative biopolymer transport protein (ExbD-like) 247 3NN7B Biopolymer transport protein ExbD/TolR U CELLULAR PROCESSES AND SIGNALING Intracellular trafficking, secretion, and vesicular transport ACIAD1591 CDS +3 1583250 1584047 no putative transcriptional regulator 525 3NM4K Crp-like helix-turn-helix domain K INFORMATION STORAGE AND PROCESSING Transcription ACIAD1592 CDS +2 1584167 1585075 no putative alkylsulfatase (Atsk-like) 613 3NJW8 Taurine catabolism dioxygenase TauD, TfdA family Q METABOLISM Secondary metabolites biosynthesis, transport and catabolism ACIAD1593 CDS +1 1585114 1586193 no atsR sulfate ester binding protein (ABC superfamily, peri_bind) 712 3NTAW NMT1-like family P METABOLISM Inorganic ion transport and metabolism ACIAD1594 CDS +3 1586229 1588517 no putative TonB-dependent receptor protein 1494 3NMZ6 Outer membrane protein beta-barrel family P METABOLISM Inorganic ion transport and metabolism ACIAD1595 CDS +3 1588572 1589909 no ntaA nitrilotriacetate monooxygenase component A (NTA monooxygenase component A) (NTA-MO A) 875 3NKW5 Luciferase-like monooxygenase C METABOLISM Energy production and conversion ACIAD1596 CDS +2 1589921 1590919 no putative oxidoreductase 668 3NKPT Aldo/keto reductase family C METABOLISM Energy production and conversion ACIAD1597 CDS -1 1590986 1593463 no putative TonB-dependent receptor 1625 3NMSM TonB dependent receptor P METABOLISM Inorganic ion transport and metabolism ACIAD1598 CDS -2 1593688 1595352 no atsA arylsulfatase (Aryl-sulfate sulphohydrolase) 1132 3NJ0S Sulfatase P METABOLISM Inorganic ion transport and metabolism ACIAD1599 CDS -2 1595470 1596291 no putative transcriptional regulator 540 3NN18 Crp-like helix-turn-helix domain K INFORMATION STORAGE AND PROCESSING Transcription ACIAD1600 CDS +3 1596513 1597466 no putative alkylsulfatase (AtsK) 644 3NMNU Taurine catabolism dioxygenase TauD, TfdA family C METABOLISM Energy production and conversion ACIAD1601 CDS +1 1597495 1598643 no atsR sulfate ester binding protein (ABC superfamily, peri_bind) 744 3NTAX NMT1-like family P METABOLISM Inorganic ion transport and metabolism ACIAD1602 CDS -2 1598767 1599651 no putative transcriptional regulator (LysR family) 582 3NT53 LysR substrate binding domain K INFORMATION STORAGE AND PROCESSING Transcription ACIAD1604 CDS +2 1599821 1601329 no mmsA methylmalonate-semialdehyde dehydrogenase, oxidoreductase protein 977 3NIFA Aldehyde dehydrogenase family C METABOLISM Energy production and conversion ACIAD1605 CDS +1 1601344 1602237 no mmsB 3-hydroxyisobutyrate dehydrogenase 575 3NKEJ Belongs to the 3-hydroxyisobutyrate dehydrogenase family I METABOLISM Lipid transport and metabolism ACIAD1606 CDS +1 1602316 1603959 no putative acetyl-coA synthetase/AMP-(fatty) acid ligase 1107 3NIWB AMP-binding enzyme C-terminal domain I METABOLISM Lipid transport and metabolism ACIAD1607 CDS +1 1604041 1605168 no acads Acyl-CoA dehydrogenase, short-chain specific 723 3NKAF Acyl-CoA dehydrogenase, C-terminal domain I METABOLISM Lipid transport and metabolism ACIAD1608 CDS +2 1605221 1605994 no FadB Enoyl-CoA hydratase (valine degradation) (valine degradation) 488 3NKER Belongs to the enoyl-CoA hydratase isomerase family I METABOLISM Lipid transport and metabolism ACIAD1609 CDS +2 1606007 1607035 no putative enoyl-CoA hydratase/isomerase family protein 681 3NKSC Enoyl-CoA hydratase/isomerase I METABOLISM Lipid transport and metabolism ACIAD1610 CDS -2 1607107 1608150 no putative transcriptional regulator (AraC family) 691 3NIIJ Arabinose-binding domain of AraC transcription regulator, N-term K INFORMATION STORAGE AND PROCESSING Transcription ACIAD1611 CDS +1 1608592 1610235 no putative acetyl-CoA synthetase/AMP-(fatty) acid ligase 1087 3NIWB AMP-binding enzyme C-terminal domain I METABOLISM Lipid transport and metabolism ACIAD1612 CDS +2 1610288 1611469 no putative acetyl-CoA C-acetyltransferase with thiolase domain 751 3NJ86 Belongs to the thiolase family I METABOLISM Lipid transport and metabolism ACIAD1613 CDS +3 1611486 1612613 no putative acyl-CoA dehydrogenase protein (acdB-like) 715 3NKAF Acyl-CoA dehydrogenase, C-terminal domain I METABOLISM Lipid transport and metabolism ACIAD1614 CDS -3 1612689 1613897 no putative nitrile hydratase activator 826 3NIRF Cobalamin synthesis protein cobW C-terminal domain S POORLY CHARACTERIZED Function unknown ACIAD1615 CDS -2 1613938 1614582 no nthB nitrile hydratase subunit beta (NHase) 447 1SDXT NHase catalyzes the hydration of various nitrile compounds to the corresponding amides E METABOLISM Amino acid transport and metabolism ACIAD1616 CDS -2 1614625 1615224 no nthA nitrile hydratase subunit alpha (NHase) 403 1RQFN Nitrile hydratase S POORLY CHARACTERIZED Function unknown ACIAD1618 CDS -2 1615309 1616823 no amdA amidase 1020 3NQQ9 Amidase J INFORMATION STORAGE AND PROCESSING Translation, ribosomal structure and biogenesis ACIAD1619 CDS -3 1616961 1617875 no conserved hypothetical protein 626 3NM9G Putative MetA-pathway of phenol degradation C METABOLISM Energy production and conversion ACIAD1620 CDS -3 1617924 1618973 no oxd Aldoxime dehydratase 734 3NRB2 Haem-containing dehydratase S POORLY CHARACTERIZED Function unknown ACIAD1622 CDS +3 1619391 1620350 no putative transcriptional regulator (AraC family) (nitrilase regulator) 644 3NTAY AraC-binding-like domain K INFORMATION STORAGE AND PROCESSING Transcription ACIAD1624 CDS -3 1620783 1621742 no putative transcriptional regulator protein with Sigma-54 factor interaction domain. 630 3NT06 Sigma-54 interaction domain K INFORMATION STORAGE AND PROCESSING Transcription ACIAD1625 CDS +3 1621989 1622762 no conserved hypothetical protein; putative membrane protein 479 3NKNM Sulfite exporter TauE/SafE S POORLY CHARACTERIZED Function unknown ACIAD1626 CDS +3 1622958 1623527 no putative outer membrane lipoprotein (lipocalin) 383 3NSQQ Lipocalin-like domain M CELLULAR PROCESSES AND SIGNALING Cell wall/membrane/envelope biogenesis ACIAD1627 CDS +2 1623653 1624624 no desC delta 9 acyl-lipid fatty acid desaturase 666 3NK3Q Fatty acid desaturase I METABOLISM Lipid transport and metabolism ACIAD1628 CDS +1 1624639 1625898 no putative dehydrogenase 867 3NKYC Flavin containing amine oxidoreductase S POORLY CHARACTERIZED Function unknown ACIAD1629 CDS +1 1625911 1626699 no conserved hypothetical protein 541 3NKTK Protein of unknown function (DUF1365) S POORLY CHARACTERIZED Function unknown ACIAD1630 CDS +1 1626703 1627902 no cfa cyclopropane-fatty-acyl-phospholipid synthase 797 3NJM9 Mycolic acid cyclopropane synthetase M CELLULAR PROCESSES AND SIGNALING Cell wall/membrane/envelope biogenesis ACIAD1631 CDS +1 1627936 1628715 no conserved hypothetical protein; putative membrane protein 527 3NKU0 Protein of unknown function (DUF1295) S POORLY CHARACTERIZED Function unknown ACIAD1632 CDS +2 1628729 1629784 no putative cyclopropane-fatty-acyl-phospholipid synthase 726 3NKMF Mycolic acid cyclopropane synthetase M CELLULAR PROCESSES AND SIGNALING Cell wall/membrane/envelope biogenesis ACIAD1633 CDS +2 1629827 1631155 no putative two-component system sensor protein (ColS-like) 889 3NTMM His Kinase A (phosphoacceptor) domain T CELLULAR PROCESSES AND SIGNALING Signal transduction mechanisms ACIAD1634 CDS -3 1631169 1631855 no putative two-component system sensor protein (ColR-like) 454 3NJNN Transcriptional regulatory protein, C terminal T CELLULAR PROCESSES AND SIGNALING Signal transduction mechanisms ACIAD1635 CDS -2 1631875 1632375 no conserved hypothetical protein; putative signal peptide 337 3NNGA Chalcone isomerase-like S POORLY CHARACTERIZED Function unknown ACIAD1636 CDS -3 1632348 1632920 no conserved hypothetical protein; putative signal peptide 377 3NITE Ketosteroid isomerase-related protein S POORLY CHARACTERIZED Function unknown ACIAD1637 CDS -1 1633010 1633558 no antibiotic resistance protein (acepita) 372 3NIRJ Acetyltransferase (GNAT) domain M CELLULAR PROCESSES AND SIGNALING Cell wall/membrane/envelope biogenesis ACIAD1638 CDS -1 1633616 1634188 no putative transcription regulator protein 372 3NNKB Helix-turn-helix XRE-family like proteins K INFORMATION STORAGE AND PROCESSING Transcription ACIAD1639 CDS +1 1635004 1637166 no putative surface protein (partial adhesin) 1103 3NIF1 Coiled stalk of trimeric autotransporter adhesin U CELLULAR PROCESSES AND SIGNALING Intracellular trafficking, secretion, and vesicular transport ACIAD1639 CDS +1 1635004 1637166 no putative surface protein (partial adhesin) 1103 3NIF1 Coiled stalk of trimeric autotransporter adhesin W CELLULAR PROCESSES AND SIGNALING Extracellular structures ACIAD1640 CDS +3 1637223 1638068 no putative antigen 556 3NJT9 SmpA / OmlA family M CELLULAR PROCESSES AND SIGNALING Cell wall/membrane/envelope biogenesis ACIAD1641 CDS +2 1638305 1638538 no hypothetical protein 162 3NPTU S POORLY CHARACTERIZED Function unknown ACIAD1642 CDS -2 1638583 1639383 no uppP undecaprenylpyrophosphate phosphatase 501 3NJBJ Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin V CELLULAR PROCESSES AND SIGNALING Defense mechanisms ACIAD1643 CDS -2 1639714 1639935 no conserved hypothetical protein 144 3NQ13 S POORLY CHARACTERIZED Function unknown ACIAD1644 CDS -1 1640135 1640362 no conserved hypothetical protein 152 3NPAF S POORLY CHARACTERIZED Function unknown ACIAD1645 CDS -2 1640614 1641699 no trmA tRNA (uracil-5-)-methyltransferase 715 3NJW0 Dual-specificity methyltransferase that catalyzes the formation of 5-methyluridine at position 54 (m5U54) in all tRNAs, and that of position 341 (m5U341) in tmRNA (transfer-mRNA) J INFORMATION STORAGE AND PROCESSING Translation, ribosomal structure and biogenesis ACIAD1646 CDS -1 1642037 1645825 no putA bifunctional protein [Includes: proline dehydrogenase (Proline oxidase); delta-1-pyrroline-5-carboxylate dehydrogenase (P5C dehydrogenase)] 2482 3NJKD Oxidizes proline to glutamate for use as a carbon and nitrogen source C METABOLISM Energy production and conversion ACIAD1646 CDS -1 1642037 1645825 no putA bifunctional protein [Includes: proline dehydrogenase (Proline oxidase); delta-1-pyrroline-5-carboxylate dehydrogenase (P5C dehydrogenase)] 2482 3NJKD Oxidizes proline to glutamate for use as a carbon and nitrogen source E METABOLISM Amino acid transport and metabolism ACIAD1648 CDS +3 1645929 1646432 no lrp leucine-responsive regulatory protein 320 3NJUQ helix_turn_helix ASNC type K INFORMATION STORAGE AND PROCESSING Transcription ACIAD1649 CDS -3 1646466 1647959 no putP SSS family, major sodium/proline symporter 963 3NIFX Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family E METABOLISM Amino acid transport and metabolism ACIAD1650 CDS -1 1648340 1649041 no npdA NAD-dependent deacetylase (Regulatory protein sirtuin family) 483 3NKCS NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form K INFORMATION STORAGE AND PROCESSING Transcription ACIAD1651 CDS -3 1649163 1650458 no pcaT dicarboxylic acid transport protein; alpha-ketoglutarate permease (MFS superfamily) 828 3NIZF Sugar (and other) transporter E METABOLISM Amino acid transport and metabolism ACIAD1651 CDS -3 1649163 1650458 no pcaT dicarboxylic acid transport protein; alpha-ketoglutarate permease (MFS superfamily) 828 3NIZF Sugar (and other) transporter G METABOLISM Carbohydrate transport and metabolism ACIAD1651 CDS -3 1649163 1650458 no pcaT dicarboxylic acid transport protein; alpha-ketoglutarate permease (MFS superfamily) 828 3NIZF Sugar (and other) transporter P METABOLISM Inorganic ion transport and metabolism ACIAD1652 CDS -2 1650775 1651692 no conserved hypothetical protein; putative peroxidase 636 3NJK9 Alpha/beta hydrolase family S POORLY CHARACTERIZED Function unknown ACIAD1653 CDS -2 1651702 1652244 no putative transcriptional regulator, PadR family 360 3NJ3A Virulence activator alpha C-term K INFORMATION STORAGE AND PROCESSING Transcription ACIAD1654 CDS +1 1652368 1654392 no fadH 2,4-dienoyl-CoA reductase 1342 3NIEV 2,4-dienoyl-coA reductase C METABOLISM Energy production and conversion ACIAD1655 CDS +2 1654472 1655605 no putative hydrolase 778 3NJ7B hydrolase of the alpha beta-hydrolase fold S POORLY CHARACTERIZED Function unknown ACIAD1656 CDS -2 1655794 1656711 no putative transcriptional regulator (LysR family) 599 3NIKU LysR substrate binding domain K INFORMATION STORAGE AND PROCESSING Transcription ACIAD1657 CDS -1 1656800 1657237 no conserved hypothetical protein 276 3NTGP HD domain K INFORMATION STORAGE AND PROCESSING Transcription ACIAD1657 CDS -1 1656800 1657237 no conserved hypothetical protein 276 3NTGP HD domain T CELLULAR PROCESSES AND SIGNALING Signal transduction mechanisms ACIAD1658 CDS +3 1657407 1657733 no conserved hypothetical protein 224 3NNVU S POORLY CHARACTERIZED Function unknown ACIAD1659 CDS -2 1657741 1658688 no putative transcriptional regulator (LysR family); putative glycine cleavage system transcriptional activator (Gcv operon activator)(GcvA) 621 3NK0E LysR substrate binding domain K INFORMATION STORAGE AND PROCESSING Transcription ACIAD1660 CDS +3 1658940 1660166 no gcdH glutaryl-CoA dehydrogenase 823 3NK12 Acyl-CoA dehydrogenase, middle domain I METABOLISM Lipid transport and metabolism ACIAD1661 CDS +1 1666354 1666896 no putative acetyltransferase 367 3NM5N Acetyltransferase (GNAT) domain S POORLY CHARACTERIZED Function unknown ACIAD1662 CDS +1 1666966 1667964 no cysK subunit of cysteine synthase A and O-acetylserine sulfhydrolase A, PLP-dependent enzyme 649 3NJTJ Belongs to the cysteine synthase cystathionine beta- synthase family E METABOLISM Amino acid transport and metabolism ACIAD1663 CDS -3 1668063 1668578 no conserved hypothetical protein 341 3NMGF Transglycosylase SLT domain M CELLULAR PROCESSES AND SIGNALING Cell wall/membrane/envelope biogenesis ACIAD1664 CDS -1 1668824 1669765 no putative phosphatidate cytidylyltransferase 613 3NK08 Cytidylyltransferase family S POORLY CHARACTERIZED Function unknown ACIAD1665 CDS -2 1669762 1670448 no plsC 1-acylglycerol-3-phosphate O-acyltransferase 454 3NMQ8 Phosphate acyltransferases I METABOLISM Lipid transport and metabolism ACIAD1666 CDS -1 1670462 1670902 no conserved hypothetical protein; putative membrane protein 270 3NND1 S POORLY CHARACTERIZED Function unknown ACIAD1667 CDS -2 1670899 1672263 no putative phosphatase 935 3NIEA Dual specificity phosphatase, catalytic domain I METABOLISM Lipid transport and metabolism ACIAD1667 CDS -2 1670899 1672263 no putative phosphatase 935 3NIEA Dual specificity phosphatase, catalytic domain T CELLULAR PROCESSES AND SIGNALING Signal transduction mechanisms ACIAD1668 CDS -2 1672279 1674027 no putative methylase 1176 3NKXM Putative methyltransferase I METABOLISM Lipid transport and metabolism ACIAD1669 CDS -1 1674047 1674688 no putative CDP-alcohol phosphatidyltransferase 405 3NKEW CDP-alcohol phosphatidyltransferase I METABOLISM Lipid transport and metabolism ACIAD1670 CDS +2 1674836 1675303 no putative prolyl-tRNA synthetases 313 3NN9F Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily S POORLY CHARACTERIZED Function unknown ACIAD1671 CDS +3 1675470 1677020 no conserved hypothetical protein 1009 3NJG6 Histidine phosphatase superfamily (branch 2) S POORLY CHARACTERIZED Function unknown ACIAD1672 CDS +2 1677269 1679410 no mtlD mannitol-1-phosphate 5-dehydrogenase 1414 3NJPB Haloacid dehalogenase-like hydrolase G METABOLISM Carbohydrate transport and metabolism ACIAD1673 CDS -2 1679602 1680294 no conserved hypothetical protein; putative membrane protein 435 3NSMF LrgB-like family M CELLULAR PROCESSES AND SIGNALING Cell wall/membrane/envelope biogenesis ACIAD1674 CDS -3 1680291 1680719 no conserved hypothetical protein; putative transporter 276 3NNYN LrgA family S POORLY CHARACTERIZED Function unknown ACIAD1675 CDS +2 1680830 1681729 no putative transcriptional regulator (LysR family) 585 3NKPU LysR substrate binding domain K INFORMATION STORAGE AND PROCESSING Transcription ACIAD1676 CDS +1 1681798 1682217 no conserved hypothetical protein; putative membrane protein 268 3NNMF Sulphur transport S POORLY CHARACTERIZED Function unknown ACIAD1677 CDS +3 1682226 1682624 no conserved hypothetical protein; putative membrane protein 262 3NNGU Transporter Component S POORLY CHARACTERIZED Function unknown ACIAD1678 CDS +1 1682629 1683507 no putative metallo-beta lactamase 594 3NIM0 Metallo-beta-lactamase superfamily S POORLY CHARACTERIZED Function unknown ACIAD1679 CDS +2 1683512 1683871 no conserved hypothetical protein; putative membrane protein 221 3NNSV Domain of unknown function (DUF202) S POORLY CHARACTERIZED Function unknown ACIAD1680 CDS -1 1684094 1685806 no etfD electron transfer flavoprotein-ubiquinone oxidoreductase (ETF-QO) (ETF-ubiquinone oxidoreductase) (ETF dehydrogenase) (Electron-transferring-flavoprotein dehydrogenase) 1191 3NK8K Electron transfer flavoprotein-ubiquinone oxidoreductase C METABOLISM Energy production and conversion ACIAD1681 CDS -3 1685937 1687178 no mucK cis,cis-muconate transport protein (MFS superfamily) 807 3NJE4 Sugar (and other) transporter E METABOLISM Amino acid transport and metabolism ACIAD1681 CDS -3 1685937 1687178 no mucK cis,cis-muconate transport protein (MFS superfamily) 807 3NJE4 Sugar (and other) transporter G METABOLISM Carbohydrate transport and metabolism ACIAD1681 CDS -3 1685937 1687178 no mucK cis,cis-muconate transport protein (MFS superfamily) 807 3NJE4 Sugar (and other) transporter P METABOLISM Inorganic ion transport and metabolism ACIAD1683 CDS +1 1687510 1688727 no caiB L-carnitine dehydrogenase 813 3NJFH CoA-transferase family III C METABOLISM Energy production and conversion ACIAD1684 CDS +3 1688853 1689698 no dcaS transcriptional regulator (IclR family) 565 3NJ66 helix_turn_helix isocitrate lyase regulation K INFORMATION STORAGE AND PROCESSING Transcription ACIAD1685 CDS -2 1689742 1690941 no putative transport protein (MFS superfamily) 756 3NJ07 Major Facilitator Superfamily E METABOLISM Amino acid transport and metabolism ACIAD1685 CDS -2 1689742 1690941 no putative transport protein (MFS superfamily) 756 3NJ07 Major Facilitator Superfamily G METABOLISM Carbohydrate transport and metabolism ACIAD1685 CDS -2 1689742 1690941 no putative transport protein (MFS superfamily) 756 3NJ07 Major Facilitator Superfamily P METABOLISM Inorganic ion transport and metabolism ACIAD1687 CDS +1 1691122 1692345 no caiB L-carnitine dehydrogenase 809 3NJFH CoA-transferase family III C METABOLISM Energy production and conversion ACIAD1688 CDS -1 1692380 1693225 no dcaR transcriptional regulator (IclR family) 557 3NJ66 helix_turn_helix isocitrate lyase regulation K INFORMATION STORAGE AND PROCESSING Transcription ACIAD1689 CDS -3 1693338 1694543 no dcaF beta-ketoadipyl CoA thiolase 765 3NIPS Belongs to the thiolase family I METABOLISM Lipid transport and metabolism ACIAD1690 CDS -1 1694564 1696081 no dcaH dehydrogenase 988 3NIJY 3-hydroxyacyl-CoA dehydrogenase, C-terminal domain I METABOLISM Lipid transport and metabolism ACIAD1691 CDS -1 1696130 1696894 no dcaC oxidoreductase; putative ketoacyl-CoA reductase 504 3NKTS Enoyl-(Acyl carrier protein) reductase I METABOLISM Lipid transport and metabolism ACIAD1691 CDS -1 1696130 1696894 no dcaC oxidoreductase; putative ketoacyl-CoA reductase 504 3NKTS Enoyl-(Acyl carrier protein) reductase Q METABOLISM Secondary metabolites biosynthesis, transport and catabolism ACIAD1692 CDS -2 1696924 1697709 no dcaE Enoyl-CoA hydratase (branched-chain amino acid degradation) 506 3NT3R Enoyl-CoA hydratase/isomerase I METABOLISM Lipid transport and metabolism ACIAD1693 CDS +1 1698028 1699182 no acads4 Acyl-CoA dehydrogenase, short-chain specific 756 3NM5W Acyl-CoA dehydrogenase, C-terminal domain C METABOLISM Energy production and conversion ACIAD1694 CDS +2 1699220 1700527 no dcaK transport protein in catabolism of dicarboxylic acids (MFS superfamily) 849 3NJE4 Sugar (and other) transporter E METABOLISM Amino acid transport and metabolism ACIAD1694 CDS +2 1699220 1700527 no dcaK transport protein in catabolism of dicarboxylic acids (MFS superfamily) 849 3NJE4 Sugar (and other) transporter G METABOLISM Carbohydrate transport and metabolism ACIAD1694 CDS +2 1699220 1700527 no dcaK transport protein in catabolism of dicarboxylic acids (MFS superfamily) 849 3NJE4 Sugar (and other) transporter P METABOLISM Inorganic ion transport and metabolism ACIAD1695 CDS +3 1700817 1701488 no dcaI 3-oxoadipate CoA-transferase subunit A 445 3NKH5 3-oxoadipate CoA-transferase activity I METABOLISM Lipid transport and metabolism ACIAD1696 CDS +2 1701485 1702159 no dcaJ 3-oxoadipate CoA-transferase subunit B 465 3NJPC 3-oxoadipate CoA-transferase activity I METABOLISM Lipid transport and metabolism ACIAD1697 CDS +2 1702244 1703560 no dcaP porin precurseur in catabolism of dicarboxylic acids 863 3NKF0 Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane M CELLULAR PROCESSES AND SIGNALING Cell wall/membrane/envelope biogenesis ACIAD1697 CDS +2 1702244 1703560 no dcaP porin precurseur in catabolism of dicarboxylic acids 863 3NKF0 Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane U CELLULAR PROCESSES AND SIGNALING Intracellular trafficking, secretion, and vesicular transport ACIAD1698 CDS +2 1703579 1704781 no putative transport protein (MFS superfamily) 783 3NJ19 Major Facilitator Superfamily E METABOLISM Amino acid transport and metabolism ACIAD1698 CDS +2 1703579 1704781 no putative transport protein (MFS superfamily) 783 3NJ19 Major Facilitator Superfamily G METABOLISM Carbohydrate transport and metabolism ACIAD1698 CDS +2 1703579 1704781 no putative transport protein (MFS superfamily) 783 3NJ19 Major Facilitator Superfamily P METABOLISM Inorganic ion transport and metabolism ACIAD1699 CDS -3 1704819 1705241 no conserved hypothetical protein; putative protein involved in aromatic compounds catabolism 275 3NP16 Thioesterase superfamily Q METABOLISM Secondary metabolites biosynthesis, transport and catabolism ACIAD1700 CDS +1 1705546 1707348 no acdB acyl-CoA dehydrogenase 1193 3NJH0 Acyl-CoA dehydrogenase N terminal C METABOLISM Energy production and conversion ACIAD1701 CDS +3 1707429 1707704 no putative enoyl-CoA hydratase 176 COG1024 Enoyl-CoA hydratase I METABOLISM Lipid transport and metabolism ACIAD1701 CDS +3 1707429 1707704 no putative enoyl-CoA hydratase 176 COG1024 Enoyl-CoA hydratase I METABOLISM Lipid transport and metabolism ACIAD1702 CDS -1 1708109 1708945 no pcaU regulatory protein for pca operon (activator) 550 3NK62 helix_turn_helix isocitrate lyase regulation K INFORMATION STORAGE AND PROCESSING Transcription ACIAD1704 CDS +2 1709228 1709914 no pcaI 3-oxoadipate CoA-transferase subunit A (Beta- ketoadipate:succinyl-CoA transferase subunit A) 448 3NKH5 3-oxoadipate CoA-transferase activity I METABOLISM Lipid transport and metabolism ACIAD1705 CDS +3 1709925 1710578 no pcaJ 3-oxoadipate CoA-transferase subunit B (Beta- ketoadipate:succinyl-CoA transferase subunit B) 443 3NJPC 3-oxoadipate CoA-transferase activity I METABOLISM Lipid transport and metabolism ACIAD1706 CDS +3 1710591 1711796 no pcaF beta-ketoadipyl CoA thiolase 766 3NIPS Belongs to the thiolase family I METABOLISM Lipid transport and metabolism ACIAD1707 CDS +2 1711808 1713163 no pcaB 3-carboxy-cis,cis-muconate cycloisomerase (3-carboxymuconate lactonizing enzyme) (CMLE) 862 3NIY1 Adenylosuccinate lyase C-terminus F METABOLISM Nucleotide transport and metabolism ACIAD1708 CDS +1 1713160 1713960 no pcaD 3-oxoadipate enol-lactonase I (Enol-lactone hydrolase I) (Beta-ketoadipate enol-lactone hydrolase I) 529 3NTMN Ndr family S POORLY CHARACTERIZED Function unknown ACIAD1709 CDS +2 1713983 1715356 no pcaK 4-hydroxybenzoate transporter (MFS superfamily) 883 3NIT1 Uncharacterised MFS-type transporter YbfB G METABOLISM Carbohydrate transport and metabolism ACIAD1710 CDS +2 1715372 1715776 no pcaC gamma-carboxymuconolactone decarboxylase (CMD) 271 3NN2V Carboxymuconolactone decarboxylase family S POORLY CHARACTERIZED Function unknown ACIAD1711 CDS +2 1715798 1716523 no pcaH protocatechuate 3,4-dioxygenase beta chain (3,4-PCD) 509 3NJIP Protocatechuate 3,4-dioxygenase beta subunit N terminal Q METABOLISM Secondary metabolites biosynthesis, transport and catabolism ACIAD1712 CDS +1 1716541 1717170 no pcaG protocatechuate 3,4-dioxygenase alpha chain (3,4-PCD) 431 3NIUN Dioxygenase Q METABOLISM Secondary metabolites biosynthesis, transport and catabolism ACIAD1713 CDS +1 1717288 1718112 no quiB catabolic 3-dehydroquinate dehydratase (3- dehydroquinase) 510 3NIYK Involved in the third step of the chorismate pathway, which leads to the biosynthesis of aromatic amino acids. Catalyzes the cis-dehydration of 3-dehydroquinate (DHQ) and introduces the first double bond of the aromatic ring to yield 3- dehydroshikimate E METABOLISM Amino acid transport and metabolism ACIAD1714 CDS +2 1718132 1719592 no quiC 3-dehydroshikimate dehydratase (DHS dehydratase) (DHSase) 916 3NJE1 Periplasmic copper-binding protein (NosD) P METABOLISM Inorganic ion transport and metabolism ACIAD1715 CDS +3 1719660 1720979 no quiX porin 905 3NK6E Carbohydrate-selective porin, OprB family M CELLULAR PROCESSES AND SIGNALING Cell wall/membrane/envelope biogenesis ACIAD1716 CDS +3 1721187 1723583 no quiA quinate/shikimate dehydrogenase [Pyrroloquinoline-quinone] (NAD(P)-independent quinate dehydrogenase) 1629 3NIK6 PQQ-like domain G METABOLISM Carbohydrate transport and metabolism ACIAD1717 CDS -3 1723656 1724834 no putative regulatory protein (PobS) 562 3NPCP COG0790 FOG TPR repeat, SEL1 subfamily S POORLY CHARACTERIZED Function unknown ACIAD1718 CDS -2 1725001 1725816 no pobR p-hydroxybenzoate hydroxylase transcriptional activator 533 3NT4U helix_turn_helix isocitrate lyase regulation K INFORMATION STORAGE AND PROCESSING Transcription ACIAD1719 CDS +3 1725951 1727165 no pobA p-hydroxybenzoate hydroxylase (4-hydroxybenzoate 3- monooxygenase) 816 3NJZH FAD binding domain C METABOLISM Energy production and conversion ACIAD1719 CDS +3 1725951 1727165 no pobA p-hydroxybenzoate hydroxylase (4-hydroxybenzoate 3- monooxygenase) 816 3NJZH FAD binding domain H METABOLISM Coenzyme transport and metabolism ACIAD1720 CDS -1 1727213 1728955 no hcaG chlorogenate esterase 1173 3NK43 Tannase and feruloyl esterase S POORLY CHARACTERIZED Function unknown ACIAD1721 CDS -3 1728978 1729367 no conserved hypothetical protein 269 3NN4V Thioesterase-like superfamily Q METABOLISM Secondary metabolites biosynthesis, transport and catabolism ACIAD1722 CDS -3 1729419 1730669 no hcaE porin 850 3NKHG outer membrane porin, OprD family S POORLY CHARACTERIZED Function unknown ACIAD1723 CDS -3 1730745 1731884 no hcaD acyl coenzyme A dehydrogenase 761 3NJFQ Acyl-CoA dehydrogenase, C-terminal domain C METABOLISM Energy production and conversion ACIAD1724 CDS -3 1731954 1733828 no hcaC coenzyme A ligase 1275 3NM61 AMP-binding enzyme I METABOLISM Lipid transport and metabolism ACIAD1724 CDS -3 1731954 1733828 no hcaC coenzyme A ligase 1275 3NM61 AMP-binding enzyme Q METABOLISM Secondary metabolites biosynthesis, transport and catabolism ACIAD1725 CDS -2 1733920 1735371 no hcaB hydroxybenzaldehyde dehydrogenase 937 3NIKA belongs to the aldehyde dehydrogenase family C METABOLISM Energy production and conversion ACIAD1726 CDS -2 1735408 1736241 no hcaA enoyl-CoA hydratase/lyase 569 3NKIM Belongs to the enoyl-CoA hydratase isomerase family I METABOLISM Lipid transport and metabolism ACIAD1727 CDS +2 1736591 1737730 no hcaK transporter of hydroxycinnamates (MFS superfamily) 700 3NKGC Major Facilitator Superfamily E METABOLISM Amino acid transport and metabolism ACIAD1727 CDS +2 1736591 1737730 no hcaK transporter of hydroxycinnamates (MFS superfamily) 700 3NKGC Major Facilitator Superfamily G METABOLISM Carbohydrate transport and metabolism ACIAD1727 CDS +2 1736591 1737730 no hcaK transporter of hydroxycinnamates (MFS superfamily) 700 3NKGC Major Facilitator Superfamily P METABOLISM Inorganic ion transport and metabolism ACIAD1728 CDS +2 1737794 1738273 no hcaR Repressor protein of the Hydroxycinnamate (hca) catabolic genes 303 3NKYG helix_turn_helix multiple antibiotic resistance protein K INFORMATION STORAGE AND PROCESSING Transcription ACIAD1729 CDS -1 1738280 1738921 no putative transcriptional regulator (TetR/AcrR family) 416 3NM7F Bacterial regulatory proteins, tetR family K INFORMATION STORAGE AND PROCESSING Transcription ACIAD1730 CDS +2 1739279 1740241 no conserved hypothetical protein 646 3NK84 Predicted metal-dependent hydrolase S POORLY CHARACTERIZED Function unknown ACIAD1731 CDS +1 1740301 1741128 no putative short-chain dehydrogenase 545 3NIU2 Belongs to the short-chain dehydrogenases reductases (SDR) family S POORLY CHARACTERIZED Function unknown ACIAD1733 CDS +2 1741220 1742749 no putative flavin-binding monooxygenase 1034 3NT7X Flavin-binding monooxygenase-like P METABOLISM Inorganic ion transport and metabolism ACIAD1734 CDS +1 1742761 1743708 no putative methyltransferase (EC 2.1.1.-) 617 3NT9V Exhibits S-adenosyl-L-methionine-dependent methyltransferase activity H METABOLISM Coenzyme transport and metabolism ACIAD1735 CDS +3 1743846 1744352 no conserved hypothetical protein; putative signal peptide 348 3NK35 S POORLY CHARACTERIZED Function unknown ACIAD1736 CDS -2 1744417 1745805 no accC biotin carboxylase (A subunit of acetyl-CoA carboxylase) 918 3NINS Biotin carboxylase I METABOLISM Lipid transport and metabolism ACIAD1737 CDS -1 1745822 1746244 no accB biotin carboxyl carrier protein of acetyl-CoA carboxylase (BCCP) 244 3NN6K first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA I METABOLISM Lipid transport and metabolism ACIAD1738 CDS -1 1746272 1746721 no aroQ 3-dehydroquinate dehydratase, type II 297 3NIYA Catalyzes a trans-dehydration via an enolate intermediate E METABOLISM Amino acid transport and metabolism ACIAD1740 CDS -2 1747804 1748688 no folE2 GTP cyclohydrolase folE2 582 3NJ6A Converts GTP to 7,8-dihydroneopterin triphosphate S POORLY CHARACTERIZED Function unknown ACIAD1741 CDS -3 1748736 1749944 no ZigA Zur-induced GTPase A 807 3NIRF Cobalamin synthesis protein cobW C-terminal domain S POORLY CHARACTERIZED Function unknown ACIAD1742 CDS -1 1750133 1750840 no putative peptidase family M15 498 3NJWK Peptidase M15 S POORLY CHARACTERIZED Function unknown ACIAD1743 CDS -3 1751010 1752011 no putative oxydoreductase protein, zinc-containing (quinone oxidoreductase, NADPH dependent) 661 3NJAB Zinc-binding dehydrogenase C METABOLISM Energy production and conversion ACIAD1744 CDS -2 1752232 1753650 no aspA aspartate ammonia-lyase (aspartase) 912 3NJZA Fumarase C C-terminus E METABOLISM Amino acid transport and metabolism ACIAD1745 CDS +2 1753787 1754677 no putative transcriptional regulator (LysR family) 573 3NM1H LysR substrate binding domain K INFORMATION STORAGE AND PROCESSING Transcription ACIAD1746 CDS +1 1754767 1754967 no hypothetical protein 72.8 3NKTR Class II Aldolase and Adducin N-terminal domain G METABOLISM Carbohydrate transport and metabolism ACIAD1747 CDS +3 1755162 1755623 no putative transcriptionnal regulator (MarR family) 301 3NNUR helix_turn_helix multiple antibiotic resistance protein K INFORMATION STORAGE AND PROCESSING Transcription ACIAD1748 CDS -2 1755694 1755951 no putative transcriptional regulator (Cro/CI family) 97.4 3NNZT Helix-turn-helix K INFORMATION STORAGE AND PROCESSING Transcription ACIAD1749 CDS -3 1756089 1757099 no cioB ubiquinol oxidase subunit II, cyanide insensitive 631 3NKBY Cytochrome bd terminal oxidase subunit II C METABOLISM Energy production and conversion ACIAD1750 CDS -1 1757096 1758523 no cioA ubiquinol oxidase subunit I, cyanide insensitive 949 3NJ8Y Ubiquinol Oxidase C METABOLISM Energy production and conversion ACIAD1751 CDS -2 1758661 1759107 no DUF2946 domain-containing protein 289 3NNBC S POORLY CHARACTERIZED Function unknown ACIAD1753 CDS +3 1759599 1761278 no mdcA malonate decarboxylase, alpha subunit 1115 3NKIU Malonate decarboxylase, alpha subunit, transporter I METABOLISM Lipid transport and metabolism ACIAD1754 CDS +2 1761272 1762180 no mdcB 2'-(5''-triphosphoribosyl)-3'-dephosphocoenzyme-A synthase 585 3NKIE Involved in the formation of 2-(5''-phosphoribosyl)-3'- dephosphocoenzyme-A, the prosthetic group of the acyl-carrier protein of the malonate decarboxylase H METABOLISM Coenzyme transport and metabolism ACIAD1755 CDS +1 1762168 1762467 no mdcC malonate decarboxylase, delta subunit 204 3NPJG Subunit of malonate decarboxylase, it is an acyl carrier protein to which acetyl and malonyl thioester residues are bound via a 2'-(5''-phosphoribosyl)-3'-dephospho-CoA prosthetic group and turn over during the catalytic mechanism C METABOLISM Energy production and conversion ACIAD1756 CDS +2 1762460 1763311 no mdcD malonate decarboxylase, beta subunit 551 3NMAH Carboxyl transferase domain I METABOLISM Lipid transport and metabolism ACIAD1757 CDS +1 1763308 1764135 no mdcE malonate decarboxylase, gamma subunit 536 3NKZ5 Malonate decarboxylase gamma subunit (MdcE) I METABOLISM Lipid transport and metabolism ACIAD1758 CDS +3 1764126 1764734 no mdcG phosphoribosyl-dephospho-CoA transferase (Holo-ACP synthase) 412 3NN4M Phosphoribosyl-dephospho-CoA transferase MdcG H METABOLISM Coenzyme transport and metabolism ACIAD1759 CDS +3 1764747 1765673 no mdcH malonate decarboxylase, epsilon subunit (acyl carrier transferase) 602 3NJXS Acyl transferase domain I METABOLISM Lipid transport and metabolism ACIAD1760 CDS +2 1765721 1766134 no mdcL malonate transporter 254 3NSRX Malonate transporter MadL subunit S POORLY CHARACTERIZED Function unknown ACIAD1761 CDS +3 1766127 1766894 no mdcM malonate transporter 474 3NKFW Malonate/sodium symporter MadM subunit S POORLY CHARACTERIZED Function unknown ACIAD1762 CDS -2 1766935 1767855 no mdcR transcriptional regulator for malonate utilization (LysR family) 579 3NKBH LysR substrate binding domain K INFORMATION STORAGE AND PROCESSING Transcription ACIAD1763 CDS -1 1767893 1768801 no srpH serine acetyltransferase 612 3NMA0 Bacterial transferase hexapeptide (six repeats) E METABOLISM Amino acid transport and metabolism ACIAD1764 CDS +2 1769018 1771192 no putative ferric siderophore receptor protein 1449 3NJIF TonB dependent receptor P METABOLISM Inorganic ion transport and metabolism ACIAD1765 CDS +3 1771665 1772951 no putative branched-chain amino acid transport protein (ABC superfamily, peri_bind) 847 3NKAD Periplasmic binding protein domain E METABOLISM Amino acid transport and metabolism ACIAD1766 CDS +3 1773033 1774679 no putative branched-chain amino acid permease protein (ABC superfamily, membrane) 1017 3NJE3 Belongs to the binding-protein-dependent transport system permease family E METABOLISM Amino acid transport and metabolism ACIAD1767 CDS +3 1774686 1775756 no putative branched-chain amino acid permease protein (ABC superfamily, membrane) 700 3NK6B Belongs to the binding-protein-dependent transport system permease family E METABOLISM Amino acid transport and metabolism ACIAD1768 CDS +3 1775757 1776584 no putative branched-chain amino acid transport protein (ABC superfamily, atp_bind) 538 3NKRP Branched-chain amino acid ATP-binding cassette transporter S POORLY CHARACTERIZED Function unknown ACIAD1769 CDS +3 1776594 1777292 no putative branched-chain amino acid transport protein (ABC superfamily, ATP_bind) 451 3NM7M ABC transporter E METABOLISM Amino acid transport and metabolism ACIAD1770 CDS +3 1777596 1777790 no hypothetical protein; putative membrane protein 45.1 3NQGS S POORLY CHARACTERIZED Function unknown ACIAD1772 CDS -2 1778317 1778766 no conserved hypothetical protein; putative signal peptide 281 3NTI2 META domain O CELLULAR PROCESSES AND SIGNALING Posttranslational modification, protein turnover, chaperones ACIAD1773 CDS +2 1779134 1780402 no putative transport protein (permease) 781 3NJ9D Major Facilitator Superfamily G METABOLISM Carbohydrate transport and metabolism ACIAD1774 CDS -2 1780468 1781904 no otsA trehalose-6-phosphate synthase 978 3NKYD Glycosyltransferase family 20 G METABOLISM Carbohydrate transport and metabolism ACIAD1775 CDS -1 1781897 1782760 no otsB trehalose-6-phosphate phosphatase, biosynthetic 561 3NM7C Removes the phosphate from trehalose 6-phosphate to produce free trehalose G METABOLISM Carbohydrate transport and metabolism ACIAD1776 CDS +3 1783137 1783610 no putative general stress protein 26 318 3NNVC Pyridoxamine 5'-phosphate oxidase like S POORLY CHARACTERIZED Function unknown ACIAD1778 CDS +3 1784139 1784624 no fecI alternative RNAP sigma factor required for fecA promoter recognition and ferric citrate transport; activated by FecR 324 3NNTZ Sigma-70, region 4 K INFORMATION STORAGE AND PROCESSING Transcription ACIAD1779 CDS +2 1784618 1785559 no fecR membrane bound regulator in multi-component regulatory system with cytoplasmic FecI (sigma factor) and FecA (outer membrane receptor) 619 3NJWP Domain of unknown function (DUF4880) P METABOLISM Inorganic ion transport and metabolism ACIAD1779 CDS +2 1784618 1785559 no fecR membrane bound regulator in multi-component regulatory system with cytoplasmic FecI (sigma factor) and FecA (outer membrane receptor) 619 3NJWP Domain of unknown function (DUF4880) T CELLULAR PROCESSES AND SIGNALING Signal transduction mechanisms ACIAD1780 CDS +2 1785641 1788112 no putative tonB-dependent ferric siderophore receptor protein 1642 3NQRP Secretin and TonB N terminus short domain P METABOLISM Inorganic ion transport and metabolism ACIAD1781 CDS +3 1788246 1789061 no conserved hypothetical protein 561 3NN22 Protein of unknown function (DUF3298) S POORLY CHARACTERIZED Function unknown ACIAD1782 CDS +2 1789403 1791484 no ppk polyphosphate kinase (Polyphosphoric acid kinase) (ATP- polyphosphate phosphotransferase) 1362 3NKPA Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP) H METABOLISM Coenzyme transport and metabolism ACIAD1783 CDS +3 1791699 1793105 no putative methylenetetrahydrofolate reductase 947 3NM8D Methylene-tetrahydrofolate reductase C terminal E METABOLISM Amino acid transport and metabolism ACIAD1784 CDS -3 1793196 1793654 no conserved hypothetical protein; putative membrane protein 290 3NNKT S POORLY CHARACTERIZED Function unknown ACIAD1786 CDS +2 1794191 1794415 no conserved hypothetical protein 151 3NPAW S POORLY CHARACTERIZED Function unknown ACIAD1787 CDS +3 1794597 1794809 no csp cold shock-like protein 142 3NQ0R 'Cold-shock' DNA-binding domain K INFORMATION STORAGE AND PROCESSING Transcription ACIAD1788 CDS +3 1794984 1797608 no conserved hypothetical protein; putative VGR-related protein 1663 3NIE7 Phage late control gene D protein (GPD) S POORLY CHARACTERIZED Function unknown ACIAD1789 CDS +2 1797605 1798288 no hypothetical protein 437 3NP76 S POORLY CHARACTERIZED Function unknown ACIAD1790 CDS +3 1798278 1799639 no hypothetical protein 909 3NIXT Evidence 5 No homology to any previously reported sequences S POORLY CHARACTERIZED Function unknown ACIAD1791 CDS -3 1799607 1800464 frameshift transposase of IS1236, IS3 family (ORF 2) 595 3NKN1 Evidence 1 Function experimentally demonstrated in the studied organism L INFORMATION STORAGE AND PROCESSING Replication, recombination and repair ACIAD1792 CDS -1 1800473 1800781 frameshift transposase of IS1236, IS3 family (ORF 1) 193 3NNW1 Evidence 1 Function experimentally demonstrated in the studied organism L INFORMATION STORAGE AND PROCESSING Replication, recombination and repair ACIAD1794 CDS +1 1800814 1802439 no hypothetical protein; putative membrane protein 1038 3NIXT Evidence 5 No homology to any previously reported sequences S POORLY CHARACTERIZED Function unknown ACIAD1795 CDS +1 1802446 1803534 no hypothetical protein; putative membrane protein 712 3NJMB S POORLY CHARACTERIZED Function unknown ACIAD1796 CDS +1 1803547 1804635 no hypothetical protein; putative membrane protein 715 3NQ0G S POORLY CHARACTERIZED Function unknown ACIAD1798 CDS +2 1804946 1806739 no putative lipopolysaccharide modification acyltransferase 1170 3NJ1U Acyltransferase family I METABOLISM Lipid transport and metabolism ACIAD1799 CDS +2 1806881 1807084 no conserved hypothetical protein 111 3NPU4 S POORLY CHARACTERIZED Function unknown ACIAD1800 CDS -2 1807210 1808064 no putative transporter (formate/nitrite transporter family) 539 3NKW0 Formate/nitrite transporter P METABOLISM Inorganic ion transport and metabolism ACIAD1801 CDS +1 1808407 1809738 no conserved hypothetical protein 921 3NJ5A Pfam:HipA_N S POORLY CHARACTERIZED Function unknown ACIAD1802 CDS +3 1809723 1810052 no putative transcriptional regulator 209 3NP09 Helix-turn-helix XRE-family like proteins K INFORMATION STORAGE AND PROCESSING Transcription ACIAD1803 CDS -3 1810056 1810778 no conserved hypothetical protein 486 3NKZ3 S POORLY CHARACTERIZED Function unknown ACIAD1804 CDS -1 1811060 1812223 no putative permease (MFS superfamily) 758 3NMRY Major Facilitator Superfamily E METABOLISM Amino acid transport and metabolism ACIAD1804 CDS -1 1811060 1812223 no putative permease (MFS superfamily) 758 3NMRY Major Facilitator Superfamily G METABOLISM Carbohydrate transport and metabolism ACIAD1804 CDS -1 1811060 1812223 no putative permease (MFS superfamily) 758 3NMRY Major Facilitator Superfamily P METABOLISM Inorganic ion transport and metabolism ACIAD1805 CDS +1 1812442 1813371 no putative glyoxalase (dioxygenase domain) 641 3NMHR Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily E METABOLISM Amino acid transport and metabolism ACIAD1806 CDS +3 1813371 1813730 no putative ferredoxin subunit (Rieske [2Fe-2S] domain) 249 1SRN4 Rieske [2Fe-2S] domain P METABOLISM Inorganic ion transport and metabolism ACIAD1807 CDS +1 1813741 1814901 no putative dipeptidyl aminopeptidase/acylaminoacyl-peptidase 796 3NQX1 Alpha/beta hydrolase of unknown function (DUF1100) S POORLY CHARACTERIZED Function unknown ACIAD1808 CDS +3 1814916 1816058 no putative monooxygenase 741 3NK2I FAD binding domain C METABOLISM Energy production and conversion ACIAD1808 CDS +3 1814916 1816058 no putative monooxygenase 741 3NK2I FAD binding domain H METABOLISM Coenzyme transport and metabolism ACIAD1809 CDS +1 1816129 1817106 no putative fumarylacetoacetate hydrolase 649 3NRFB Fumarylacetoacetate (FAA) hydrolase family Q METABOLISM Secondary metabolites biosynthesis, transport and catabolism ACIAD1811 CDS -3 1817589 1818026 no putative transcriptional regulator (MarR/EmrR family) 269 3NSDC Winged helix DNA-binding domain K INFORMATION STORAGE AND PROCESSING Transcription ACIAD1812 CDS -2 1818139 1818924 no putative cyclase 555 1S0FT Metal-dependent hydrolase S POORLY CHARACTERIZED Function unknown ACIAD1813 CDS -2 1818955 1819884 no conserved hypothetical protein; putative signal peptide 629 3NTJF Putative MetA-pathway of phenol degradation C METABOLISM Energy production and conversion ACIAD1814 CDS +3 1820367 1821236 no conserved hypothetical protein; putative signal peptide 592 3NMAR Putative MetA-pathway of phenol degradation C METABOLISM Energy production and conversion ACIAD1815 CDS +1 1821361 1822713 no putative benzoate transport protein (BenK-like)(MFS superfamily) 823 3NM0W Major Facilitator E METABOLISM Amino acid transport and metabolism ACIAD1815 CDS +1 1821361 1822713 no putative benzoate transport protein (BenK-like)(MFS superfamily) 823 3NM0W Major Facilitator G METABOLISM Carbohydrate transport and metabolism ACIAD1815 CDS +1 1821361 1822713 no putative benzoate transport protein (BenK-like)(MFS superfamily) 823 3NM0W Major Facilitator P METABOLISM Inorganic ion transport and metabolism ACIAD1816 CDS -1 1822769 1823329 no conserved hypothetical protein 393 1T0WB SnoaL-like domain Q METABOLISM Secondary metabolites biosynthesis, transport and catabolism ACIAD1817 CDS +3 1823583 1824239 no putative transcriptional regulator (AraC family) 416 3NS66 helix_turn_helix, arabinose operon control protein K INFORMATION STORAGE AND PROCESSING Transcription ACIAD1818 CDS +1 1824526 1826163 no alkK medium-chain-fatty-acid-CoA ligase 1102 3NJQ7 AMP-binding enzyme C-terminal domain I METABOLISM Lipid transport and metabolism ACIAD1818 CDS +1 1824526 1826163 no alkK medium-chain-fatty-acid-CoA ligase 1102 3NJQ7 AMP-binding enzyme C-terminal domain Q METABOLISM Secondary metabolites biosynthesis, transport and catabolism ACIAD1819 CDS +3 1826187 1827290 no putative acyl-CoA dehydrogenase 697 1RS45 COG1960 Acyl-CoA dehydrogenases I METABOLISM Lipid transport and metabolism ACIAD1820 CDS +2 1827314 1828090 no scpB Methylmalonyl-CoA decarboxylase 498 3NKJ9 Enoyl-CoA hydratase/isomerase I METABOLISM Lipid transport and metabolism ACIAD1821 CDS +1 1828090 1829238 no putative acyl-CoA dehydrogenase 779 3NQZ7 Acyl-CoA dehydrogenase, middle domain C METABOLISM Energy production and conversion ACIAD1822 CDS -2 1829293 1830072 no putative transcriptional regulator (IcIR family) 504 1SKGD IclR helix-turn-helix domain K INFORMATION STORAGE AND PROCESSING Transcription ACIAD1824 CDS +1 1830244 1830999 no putative oxidoreductase, short-chain dehydrogenase/reductase 478 3NMP9 KR domain I METABOLISM Lipid transport and metabolism ACIAD1824 CDS +1 1830244 1830999 no putative oxidoreductase, short-chain dehydrogenase/reductase 478 3NMP9 KR domain Q METABOLISM Secondary metabolites biosynthesis, transport and catabolism ACIAD1825 CDS +2 1831163 1832056 no putative transcriptional regulator; putative regucalcin family protein 612 3NRK3 SMP-30/Gluconolaconase/LRE-like region K INFORMATION STORAGE AND PROCESSING Transcription ACIAD1826 CDS +2 1832066 1834171 no pauA pimeloyl-CoA synthetase 1352 1RPXX Acyl-CoA synthetase (NDP forming) C METABOLISM Energy production and conversion ACIAD1827 CDS +2 1834181 1834837 no putative flavoprotein oxidoreductase 438 1SEEY Flavin reductase like domain S POORLY CHARACTERIZED Function unknown ACIAD1828 CDS +2 1834859 1836451 no putative short-chain dehydrogenase/reductase SDR protein 1036 3NMP9 KR domain I METABOLISM Lipid transport and metabolism ACIAD1828 CDS +2 1834859 1836451 no putative short-chain dehydrogenase/reductase SDR protein 1036 3NMP9 KR domain Q METABOLISM Secondary metabolites biosynthesis, transport and catabolism ACIAD1829 CDS +3 1836465 1837568 no putative enoyl-CoA hydratase (PaaG-like) 733 3NJJP Enoyl-CoA hydratase/isomerase I METABOLISM Lipid transport and metabolism ACIAD1830 CDS +2 1837793 1838863 no putative monooxygenase 701 3NK6K Luciferase-like monooxygenase C METABOLISM Energy production and conversion ACIAD1831 CDS -2 1839058 1839816 no conserved hypothetical protein 503 3NSXC Metal dependent phosphohydrolases with conserved 'HD' motif. S POORLY CHARACTERIZED Function unknown ACIAD1832 CDS -1 1840028 1840264 no conserved hypothetical protein 159 3NPB2 DNA-binding protein VF530 S POORLY CHARACTERIZED Function unknown ACIAD1834 CDS +1 1840870 1841769 no putative transcription regulator (AraC family) 570 3NMK9 AraC-type transcriptional regulator N-terminus K INFORMATION STORAGE AND PROCESSING Transcription ACIAD1835 CDS +2 1841924 1842838 no conserved hypothetical protein; putative hydrolase of the alpha/beta superfamily 609 3NSZX BAAT / Acyl-CoA thioester hydrolase C terminal S POORLY CHARACTERIZED Function unknown ACIAD1836 CDS +2 1843016 1844167 no putative oxidoreductase (NADH-dependent flavin oxidoreductase) 754 3NSWS NADH:flavin oxidoreductase / NADH oxidase family C METABOLISM Energy production and conversion ACIAD1837 CDS +3 1844196 1844357 no hypothetical protein 60.1 3NTMP AraC-type transcriptional regulator N-terminus K INFORMATION STORAGE AND PROCESSING Transcription ACIAD1838 CDS +2 1844348 1845091 no putative transcriptional regulator (AraC family) 465 3NTMP AraC-type transcriptional regulator N-terminus K INFORMATION STORAGE AND PROCESSING Transcription ACIAD1839 CDS +2 1845239 1845898 no putative transcriptional regulator (AraC family) 418 3NTKH AraC-type transcriptional regulator N-terminus K INFORMATION STORAGE AND PROCESSING Transcription ACIAD1840 CDS +3 1845891 1846157 no putative transcriptional regulator (AraC family) 172 3NTMP AraC-type transcriptional regulator N-terminus K INFORMATION STORAGE AND PROCESSING Transcription ACIAD1841 CDS +1 1846495 1846911 no hypothetical protein; putative membrane protein 256 3NQNG S POORLY CHARACTERIZED Function unknown ACIAD1842 CDS +1 1846915 1847328 no conserved hypothetical protein 276 3NPNW S POORLY CHARACTERIZED Function unknown ACIAD1843 CDS -3 1847589 1847783 no conserved hypothetical protein 119 3NPSE S POORLY CHARACTERIZED Function unknown ACIAD1844 CDS +1 1847896 1848144 no conserved hypothetical protein 172 3NPWE S POORLY CHARACTERIZED Function unknown ACIAD1845 CDS +2 1848146 1848571 no conserved hypothetical protein 280 3NRBQ S POORLY CHARACTERIZED Function unknown ACIAD1846 CDS -3 1848786 1849100 no putative prophage DNA binding protein (RstB-like) 216 3NP3D S POORLY CHARACTERIZED Function unknown ACIAD1847 CDS -1 1849100 1850263 no putative phage replication initiation factor (RstA-like) 797 3NSUS Evidence 3 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology L INFORMATION STORAGE AND PROCESSING Replication, recombination and repair ACIAD1848 CDS -2 1850257 1850544 no putative prophage repressor of phage gene expression protein (RstR-like) 196 3NPK1 S POORLY CHARACTERIZED Function unknown ACIAD1849 CDS +2 1850597 1850794 no putative repressor of phage gene expression protein (RstR-like) 128 3NS5E Evidence 5 No homology to any previously reported sequences S POORLY CHARACTERIZED Function unknown ACIAD1852 CDS -1 1851833 1853137 no phage-related protein (zonula occludens toxin like) 857 3NNQ9 Zonular occludens toxin (Zot) S POORLY CHARACTERIZED Function unknown ACIAD1853 CDS -2 1853134 1853412 no putative viron assembly protein 162 3NSC5 Protein of unknown function (DUF2523) S POORLY CHARACTERIZED Function unknown ACIAD1854 CDS -3 1853415 1854824 no putative recognize infection receptor (OrfU like) 91.7 3NN74 S POORLY CHARACTERIZED Function unknown ACIAD1855 CDS -2 1854952 1855221 no putative prophage major coat protein (Cep like) 163 3NS70 S POORLY CHARACTERIZED Function unknown ACIAD1857 CDS -1 1855832 1856146 no putative prophage binding protein (RtsB-like) 216 3NP3D S POORLY CHARACTERIZED Function unknown ACIAD1858 CDS -2 1856146 1857309 no putative phage replication initiation factor (RstA-like) 797 3NSUS Evidence 3 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology L INFORMATION STORAGE AND PROCESSING Replication, recombination and repair ACIAD1859 CDS -3 1857303 1857590 no putative prophage repressor of phage gene expression protein (RstR-like) 196 3NPK1 S POORLY CHARACTERIZED Function unknown ACIAD1860 CDS +1 1857643 1857840 no putative repressor of phage gene expression protein (RstR-like) 128 3NS5E Evidence 5 No homology to any previously reported sequences S POORLY CHARACTERIZED Function unknown ACIAD1862 CDS -3 1858368 1859210 no conserved hypothetical protein 558 3NKJM S POORLY CHARACTERIZED Function unknown ACIAD1864 CDS +1 1859557 1860123 no putative transcriptional regulator (TetR family) 380 3NKIP Bacterial regulatory proteins, tetR family K INFORMATION STORAGE AND PROCESSING Transcription ACIAD1865 CDS +3 1860447 1860755 no putative transcriptional regulator (ArsR family) 192 3NNVM helix_turn_helix, Arsenical Resistance Operon Repressor K INFORMATION STORAGE AND PROCESSING Transcription ACIAD1866 CDS +3 1860954 1862153 no sstT transporter, sodium-dicarboxylate symporter family 717 3NIMG Involved in the import of serine and threonine into the cell, with the concomitant import of sodium (symport system) E METABOLISM Amino acid transport and metabolism ACIAD1867 CDS +2 1862192 1862866 no conserved hypothetical protein; putative membrane protein. 428 3NITJ Protein of unknown function (DUF1275) S POORLY CHARACTERIZED Function unknown ACIAD1868 CDS +2 1862882 1863418 no putative nucleoprotein/polynucleotide-associated enzyme 332 3NJAT Uncharacterized protein conserved in bacteria (DUF2058) S POORLY CHARACTERIZED Function unknown ACIAD1869 CDS +3 1863540 1864820 no putative transporter with mechanosensitive ion channel. 803 3NJEP Mechanosensitive ion channel M CELLULAR PROCESSES AND SIGNALING Cell wall/membrane/envelope biogenesis ACIAD1870 CDS -3 1864845 1866008 no putative metabolite transporter (MFS superfamily) 759 3NK1N MFS_1 like family E METABOLISM Amino acid transport and metabolism ACIAD1870 CDS -3 1864845 1866008 no putative metabolite transporter (MFS superfamily) 759 3NK1N MFS_1 like family G METABOLISM Carbohydrate transport and metabolism ACIAD1870 CDS -3 1864845 1866008 no putative metabolite transporter (MFS superfamily) 759 3NK1N MFS_1 like family P METABOLISM Inorganic ion transport and metabolism ACIAD1873 CDS +2 1866473 1868323 no putative transport protein (ABC superfamily, ATP_bind) 1189 3NJ3N ABC transporter V CELLULAR PROCESSES AND SIGNALING Defense mechanisms ACIAD1874 CDS +1 1868323 1868769 no conserved hypothetical protein; putative dehydratase 306 3NK8Y N-terminal half of MaoC dehydratase I METABOLISM Lipid transport and metabolism ACIAD1875 CDS +1 1868839 1869897 no putative transcriptional regulator (AraC family) 700 3NIFS Arabinose-binding domain of AraC transcription regulator, N-term K INFORMATION STORAGE AND PROCESSING Transcription ACIAD1876 CDS +2 1869968 1870342 no gcvH glycine cleavage complex protein H, carrier of aminomethyl moiety via covalently bound lipoyl cofactor 256 3NNJE The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein E METABOLISM Amino acid transport and metabolism ACIAD1878 CDS -3 1870386 1871441 no aro 3-deoxy-D-arabinoheptulosonate-7-phosphate synthase (DAHP synthetase), tyrosine repressible 695 3NIQP Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP) E METABOLISM Amino acid transport and metabolism ACIAD1879 CDS -3 1871988 1873097 no frmA Alcohol dehydrogenase class 3 (Alcohol dehydrogenase class III) (S-(hydroxymethyl)glutathione dehydrogenase) (Glutathione-dependent formaldehyde dehydrogenase) (FDH) (FALDH) 749 3NIU1 Belongs to the zinc-containing alcohol dehydrogenase family. Class-III subfamily C METABOLISM Energy production and conversion ACIAD1880 CDS -3 1873119 1873394 no frmR transcriptional repressor frmR 169 3NSSB Metal-sensitive transcriptional repressor S POORLY CHARACTERIZED Function unknown ACIAD1881 CDS +1 1873639 1875201 no putative phospholipase D protein 1050 3NK7J Phospholipase D I METABOLISM Lipid transport and metabolism ACIAD1882 CDS -3 1875207 1875791 no putative G:T/U mismatch-specific DNA glycosylase 393 3NTF7 DNA glycosylase L INFORMATION STORAGE AND PROCESSING Replication, recombination and repair ACIAD1883 CDS -2 1875793 1876542 no putative oxidoreductase (short chain dehydrogenase) 484 3NK19 Belongs to the short-chain dehydrogenases reductases (SDR) family S POORLY CHARACTERIZED Function unknown ACIAD1884 CDS -1 1876550 1877248 no putative phosphoglycerate mutase related protein 473 3NKBA Phosphoglycerate mutase family G METABOLISM Carbohydrate transport and metabolism ACIAD1885 CDS -2 1877263 1878366 no conserved hypothetical protein; putative phosphotransferase 754 3NKPM Phosphotransferase enzyme family S POORLY CHARACTERIZED Function unknown ACIAD1886 CDS -1 1878395 1879636 no acads1 Acyl-CoA dehydrogenase, short-chain specific 836 3NJG4 acyl-CoA dehydrogenase I METABOLISM Lipid transport and metabolism ACIAD1887 CDS +3 1879728 1880657 no putative transcriptional regulator (LysR family) 605 3NJQQ Bacterial regulatory helix-turn-helix protein, lysR family K INFORMATION STORAGE AND PROCESSING Transcription ACIAD1888 CDS -2 1880716 1881318 no putative oxydoreductase related to nitroreductase 397 3NM2B Nitroreductase family S POORLY CHARACTERIZED Function unknown ACIAD1889 CDS -3 1881450 1881941 no conserved hypothetical protein 324 3NMEE S POORLY CHARACTERIZED Function unknown ACIAD1890 CDS -1 1882037 1883431 no fumC fumarase C (fumarate hydratase Class II) 903 3NJE0 Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate C METABOLISM Energy production and conversion ACIAD1891 CDS -3 1883580 1884584 no putative UDP-galactose 4-epimerase (GalE-like) 654 3NJJM RmlD substrate binding domain M CELLULAR PROCESSES AND SIGNALING Cell wall/membrane/envelope biogenesis ACIAD1892 CDS +2 1884656 1885024 no putative intracellular sulfur oxidation protein (DsrE-like) 246 3NNIX DsrE/DsrF-like family P METABOLISM Inorganic ion transport and metabolism ACIAD1893 CDS +1 1885069 1885419 no conserved hypothetical protein 216 3NNYQ S POORLY CHARACTERIZED Function unknown ACIAD1894 CDS +2 1885427 1885708 no conserved hypothetical protein 95.5 3NPR7 S POORLY CHARACTERIZED Function unknown ACIAD1895 CDS +1 1885732 1886043 no putative sulfurtransferase 211 3NNJT Part of a sulfur-relay system P METABOLISM Inorganic ion transport and metabolism ACIAD1896 CDS -1 1886048 1886923 no putative permease (drug/metabolite transporter) 555 3NJUW EamA-like transporter family E METABOLISM Amino acid transport and metabolism ACIAD1896 CDS -1 1886048 1886923 no putative permease (drug/metabolite transporter) 555 3NJUW EamA-like transporter family G METABOLISM Carbohydrate transport and metabolism ACIAD1897 CDS +1 1887046 1888446 no putative transcriptional regulator (GntR family) 934 3NJAE helix_turn_helix gluconate operon transcriptional repressor K INFORMATION STORAGE AND PROCESSING Transcription ACIAD1899 CDS -2 1888570 1889217 no modC molybdate transport protein (ABC superfamily, atp_bind) 430 3NK39 ABC transporter P METABOLISM Inorganic ion transport and metabolism ACIAD1900 CDS -3 1889214 1889897 no modB molybdate transport protein (ABC superfamily, membrane) 429 3NM0V COG4149 ABC-type molybdate transport system, permease component P METABOLISM Inorganic ion transport and metabolism ACIAD1901 CDS -1 1889906 1890667 no modA molybdate transport protein (ABC superfamily, peri_bind) 492 3NKVC Bacterial extracellular solute-binding protein P METABOLISM Inorganic ion transport and metabolism ACIAD1902 CDS -3 1890678 1891904 no moeA molybdopterin biosynthesis protein 798 3NJX7 Probable molybdopterin binding domain H METABOLISM Coenzyme transport and metabolism ACIAD1903 CDS -1 1891904 1892827 no moaCB bifunctional protein [Includes: molybdenum cofactor biosynthesis protein C; molybdenum cofactor biosynthesis protein B] 610 3NKK0 Catalyzes the conversion of (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate to cyclic pyranopterin monophosphate (cPMP) H METABOLISM Coenzyme transport and metabolism ACIAD1904 CDS -2 1892848 1893402 no moaE molybdopterin converting factor, large subunit 342 3NK9M Molybdopterin converting factor, large subunit H METABOLISM Coenzyme transport and metabolism ACIAD1905 CDS -1 1893359 1893610 no conserved hypothetical protein 164 3NPTK ThiS family H METABOLISM Coenzyme transport and metabolism ACIAD1906 CDS -1 1893611 1894618 no moaA molybdopterin biosynthesis, protein A 684 3NKDX Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate H METABOLISM Coenzyme transport and metabolism ACIAD1907 CDS -3 1894746 1895405 no mobA molybdopterin-guanine dinucleotide synthase 444 3NKRG Transfers a GMP moiety from GTP to Mo-molybdopterin (Mo- MPT) cofactor (Moco or molybdenum cofactor) to form Mo- molybdopterin guanine dinucleotide (Mo-MGD) cofactor H METABOLISM Coenzyme transport and metabolism ACIAD1908 CDS -1 1895381 1898179 no nasA nitrate reductase, large subunit 1883 3NJ0R Belongs to the prokaryotic molybdopterin-containing oxidoreductase family C METABOLISM Energy production and conversion ACIAD1909 CDS -1 1898213 1899850 no putative nitrate reductase (electron transfer subunit) AND putative nitrite reductase (small subunit) 1092 3NK2Y Rieske-like [2Fe-2S] domain C METABOLISM Energy production and conversion ACIAD1909 CDS -1 1898213 1899850 no putative nitrate reductase (electron transfer subunit) AND putative nitrite reductase (small subunit) 1092 3NK2Y Rieske-like [2Fe-2S] domain P METABOLISM Inorganic ion transport and metabolism ACIAD1910 CDS -2 1899862 1902429 no nasD nitrite reductase, large subunit, nucleotide- and Fe/S-cluster binding 1705 3NK8P Belongs to the nitrite and sulfite reductase 4Fe-4S domain family C METABOLISM Energy production and conversion ACIAD1911 CDS -2 1902439 1903785 no putative nitrate transporter transmembrane protein (MFS superfamily) 860 3NIZB Major Facilitator Superfamily P METABOLISM Inorganic ion transport and metabolism ACIAD1913 CDS +1 1904224 1904829 no nasT response regulator protein 383 3NJ1Z ANTAR T CELLULAR PROCESSES AND SIGNALING Signal transduction mechanisms ACIAD1914 CDS +2 1904816 1905847 no putative nitrate transport protein (NasF) 682 3NITQ NMT1-like family P METABOLISM Inorganic ion transport and metabolism ACIAD1915 CDS +3 1906023 1908413 no putative molybdopterin oxidoreductase, alpha subunit (fdhA) 1638 3NKKU Belongs to the prokaryotic molybdopterin-containing oxidoreductase family C METABOLISM Energy production and conversion ACIAD1916 CDS +1 1908406 1909227 no fdhD formate dehydrogenase formation protein 535 3NJ6X Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH C METABOLISM Energy production and conversion ACIAD1917 CDS -2 1909255 1909461 no hypothetical protein 143 3NRYD Protein of unknown function (DUF2536) S POORLY CHARACTERIZED Function unknown ACIAD1919 CDS +2 1909706 1910251 no conserved hypothetical protein 360 3NIZ6 Lecithin retinol acyltransferase K INFORMATION STORAGE AND PROCESSING Transcription ACIAD1919 CDS +2 1909706 1910251 no conserved hypothetical protein 360 3NIZ6 Lecithin retinol acyltransferase T CELLULAR PROCESSES AND SIGNALING Signal transduction mechanisms ACIAD1920 CDS -1 1910414 1912141 no glnS glutaminyl-tRNA synthetase 1166 3NK4U tRNA synthetases class I (E and Q), anti-codon binding domain J INFORMATION STORAGE AND PROCESSING Translation, ribosomal structure and biogenesis ACIAD1921 CDS +1 1912309 1912818 no ppiB peptidyl-prolyl cis-trans isomerase precursor (PPIase) (Rotamase) 337 3NKAW PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides G METABOLISM Carbohydrate transport and metabolism ACIAD1922 CDS +2 1912838 1913566 no lpxH UDP-2,3-diacylglucosamine hydrolase 504 3NISI Hydrolyzes the pyrophosphate bond of UDP-2,3- diacylglucosamine to yield 2,3-diacylglucosamine 1-phosphate (lipid X) and UMP by catalyzing the attack of water at the alpha-P atom. Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell S POORLY CHARACTERIZED Function unknown ACIAD1923 CDS +1 1913656 1914324 no nfnB oxygen-insensitive NADPH nitroreductase 435 3NIWS nitroreductase C METABOLISM Energy production and conversion ACIAD1924 CDS -2 1914370 1915221 no putative integral membrane protein 510 3NSZJ EamA-like transporter family E METABOLISM Amino acid transport and metabolism ACIAD1924 CDS -2 1914370 1915221 no putative integral membrane protein 510 3NSZJ EamA-like transporter family G METABOLISM Carbohydrate transport and metabolism ACIAD1925 CDS -2 1915285 1916322 no fda fructose-1,6-bisphosphate aldolase, class II 684 3NJKM Fructose-bisphosphate aldolase class-II G METABOLISM Carbohydrate transport and metabolism ACIAD1926 CDS -1 1916444 1916701 no conserved hypothetical protein 156 3NPU6 S POORLY CHARACTERIZED Function unknown ACIAD1927 CDS -3 1916850 1918037 no pgk phosphoglycerate kinase 741 3NIZZ Belongs to the phosphoglycerate kinase family F METABOLISM Nucleotide transport and metabolism ACIAD1929 CDS +1 1918186 1918569 no conserved hypothetical protein 279 3NN33 Uncharacterized protein conserved in bacteria (DUF2237) S POORLY CHARACTERIZED Function unknown ACIAD1930 CDS +3 1918569 1919165 no conserved hypothetical protein; putative Maf-like protein 390 3NJ5U Maf-like protein D CELLULAR PROCESSES AND SIGNALING Cell cycle control, cell division, chromosome partitioning ACIAD1931 CDS -2 1919260 1920573 no putative magnesium citrate secondary transporter 805 3NJIG Citrate transporter C METABOLISM Energy production and conversion ACIAD1933 CDS +1 1920832 1921998 no conserved hypothetical protein 780 3NKNX A domain family that is part of the cupin metalloenzyme superfamily. S POORLY CHARACTERIZED Function unknown ACIAD1934 CDS +2 1922114 1923784 no putative glutamate synthase. 1130 3NJEJ Belongs to the glutamate synthase family E METABOLISM Amino acid transport and metabolism ACIAD1935 CDS -1 1923845 1924966 no putative sigma-54 dependent transcriptional regulator 738 3NJZM Sigma-54 interaction domain K INFORMATION STORAGE AND PROCESSING Transcription ACIAD1936 CDS -1 1925132 1925998 no conserved hypothetical protein; putative signal peptide 575 3NM9G Putative MetA-pathway of phenol degradation C METABOLISM Energy production and conversion ACIAD1937 CDS -3 1926258 1927001 no braG branched-chain amino acid transport protein (ABC superfamily, ATP_bind) 469 3NM7M ABC transporter E METABOLISM Amino acid transport and metabolism ACIAD1938 CDS -1 1927016 1928437 no conserved hypothetical protein; putative membrane protein 944 3NMUF Periplasmic binding protein E METABOLISM Amino acid transport and metabolism ACIAD1939 CDS -3 1928463 1929533 no braE branched-chain amino acid transport protein (ABC superfamily, membrane) 665 3NK6B Belongs to the binding-protein-dependent transport system permease family E METABOLISM Amino acid transport and metabolism ACIAD1940 CDS -1 1929536 1930417 no putative branched-chain amino acid permease protein (ABC superfamily, membrane) 533 3NJE3 Belongs to the binding-protein-dependent transport system permease family E METABOLISM Amino acid transport and metabolism ACIAD1941 CDS -1 1930445 1931248 no braF branched-chain amino acid transport protein (ABC superfamily, atp_bind) 514 3NT1M Branched-chain amino acid ATP-binding cassette transporter E METABOLISM Amino acid transport and metabolism ACIAD1942 CDS -1 1931255 1932472 no putative long-chain-fatty-acid--CoA ligase-related protein 781 3NNJB AMP-binding enzyme I METABOLISM Lipid transport and metabolism ACIAD1943 CDS -3 1932672 1933700 no conserved hypothetical protein; putative lysophospholipase 712 3NKB1 Serine aminopeptidase, S33 I METABOLISM Lipid transport and metabolism ACIAD1944 CDS -3 1933701 1934855 no conserved hypothetical protein 736 3NK61 DUF218 domain S POORLY CHARACTERIZED Function unknown ACIAD1945 CDS -3 1934862 1935899 no murB UDP-N-acetylenolpyruvoylglucosamine reductase, FAD-binding 692 3NJ3H Cell wall formation M CELLULAR PROCESSES AND SIGNALING Cell wall/membrane/envelope biogenesis ACIAD1946 CDS -3 1935924 1936427 no putative phosphotyrosine protein phosphatase (PtpA) 345 3NMJ5 Belongs to the low molecular weight phosphotyrosine protein phosphatase family T CELLULAR PROCESSES AND SIGNALING Signal transduction mechanisms ACIAD1948 CDS -2 1937095 1937304 no csp cold shock-like protein 143 3NPBG Cold shock protein domain K INFORMATION STORAGE AND PROCESSING Transcription ACIAD1950 CDS +3 1937790 1938950 no putative iron-containing alcohol dehydrogenase 741 3NJ3I Iron-containing alcohol dehydrogenase C METABOLISM Energy production and conversion ACIAD1951 CDS +2 1938947 1939393 no conserved hypothetical protein ; putative thioesterase 301 3NNN3 Acyl-ACP thioesterase S POORLY CHARACTERIZED Function unknown ACIAD1952 CDS -2 1939474 1940052 no terZ tellurium resistance protein 385 3NIJQ TerD domain T CELLULAR PROCESSES AND SIGNALING Signal transduction mechanisms ACIAD1953 CDS -3 1940085 1940804 no conserved hypothetical protein 465 3NKEU Mitochondrial biogenesis AIM24 S POORLY CHARACTERIZED Function unknown ACIAD1954 CDS -3 1940817 1942127 no putative tellurium resistance protein (TerF) 852 3NJRW vWA found in TerF C terminus T CELLULAR PROCESSES AND SIGNALING Signal transduction mechanisms ACIAD1955 CDS -2 1942195 1942770 no terE tellurium resistance protein 374 3NJ28 TerD domain T CELLULAR PROCESSES AND SIGNALING Signal transduction mechanisms ACIAD1956 CDS -1 1942859 1943929 no conserved hypothetical protein; putative membrane protein 674 3NIFU Protein of unknown function (DUF475) S POORLY CHARACTERIZED Function unknown ACIAD1957 CDS -1 1943990 1944568 no terD tellurium resistance protein 382 3NJ3C TerD domain T CELLULAR PROCESSES AND SIGNALING Signal transduction mechanisms ACIAD1958 CDS -3 1944672 1945871 no terA tellurium resistance protein 770 3NII5 TerD domain T CELLULAR PROCESSES AND SIGNALING Signal transduction mechanisms ACIAD1959 CDS -2 1945897 1946778 no conserved hypothetical protein 588 3NJ9X C-C_Bond_Lyase of the TIM-Barrel fold G METABOLISM Carbohydrate transport and metabolism ACIAD1960 CDS -1 1946783 1947934 no stiP Cysteine protease StiP 739 3NM3S PELOTA RNA binding domain J INFORMATION STORAGE AND PROCESSING Translation, ribosomal structure and biogenesis ACIAD1961 CDS -3 1947918 1948748 no conserved hypothetical protein 561 3NKPE haloacid dehalogenase-like hydrolase S POORLY CHARACTERIZED Function unknown ACIAD1962 CDS -2 1948732 1949871 no conserved hypothetical protein 754 3NK4A Phosphoribosyl transferase F METABOLISM Nucleotide transport and metabolism ACIAD1963 CDS -2 1949914 1950966 no conserved hypothetical protein 711 3NMYH ATP-grasp in the biosynthetic pathway with Ter operon H METABOLISM Coenzyme transport and metabolism ACIAD1963 CDS -2 1949914 1950966 no conserved hypothetical protein 711 3NMYH ATP-grasp in the biosynthetic pathway with Ter operon J INFORMATION STORAGE AND PROCESSING Translation, ribosomal structure and biogenesis ACIAD1964 CDS -3 1950963 1952492 no conserved hypothetical protein; putative protein kinase 1061 3NIIH Lipopolysaccharide kinase (Kdo/WaaP) family S POORLY CHARACTERIZED Function unknown ACIAD1965 CDS -2 1952485 1954293 no hypothetical protein; putative conserved domain 1178 3NJU2 Serine/threonine phosphatases, family 2C, catalytic domain T CELLULAR PROCESSES AND SIGNALING Signal transduction mechanisms ACIAD1966 CDS -2 1954315 1955373 no conserved hypothetical protein; putative tellurium resistance protein 734 3NKP1 TerY-C metal binding domain S POORLY CHARACTERIZED Function unknown ACIAD1967 CDS -2 1955407 1956042 no putative tellurium resistance protein (TerY-like) 407 3NM8K von Willebrand factor type A domain S POORLY CHARACTERIZED Function unknown ACIAD1968 CDS -1 1956080 1956721 no terX tellurium resistance protein 423 3NM96 TerD domain T CELLULAR PROCESSES AND SIGNALING Signal transduction mechanisms ACIAD1969 CDS -3 1956756 1957394 no terY tellurium resistance protein 410 3NJPJ von Willebrand factor (vWF) type A domain S POORLY CHARACTERIZED Function unknown ACIAD1970 CDS -2 1957924 1960059 no dnaX DNA polymerase III, tau and gamma subunits (DNA elongation factor III) 1348 3NJIZ DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity H METABOLISM Coenzyme transport and metabolism ACIAD1971 CDS -2 1960201 1961700 no smvA methyl viologen resistance protein (MFS superfamily) 902 3NJYN Major Facilitator Superfamily E METABOLISM Amino acid transport and metabolism ACIAD1971 CDS -2 1960201 1961700 no smvA methyl viologen resistance protein (MFS superfamily) 902 3NJYN Major Facilitator Superfamily G METABOLISM Carbohydrate transport and metabolism ACIAD1971 CDS -2 1960201 1961700 no smvA methyl viologen resistance protein (MFS superfamily) 902 3NJYN Major Facilitator Superfamily P METABOLISM Inorganic ion transport and metabolism ACIAD1973 CDS +2 1961807 1962409 no putative transcriptional regulator 398 3NJF3 Bacterial regulatory proteins, tetR family K INFORMATION STORAGE AND PROCESSING Transcription ACIAD1974 CDS -2 1962406 1963662 no conserved hypothetical protein; putative esterase 855 3NIR0 Beta-lactamase V CELLULAR PROCESSES AND SIGNALING Defense mechanisms ACIAD1975 CDS -1 1963724 1964578 no conserved hypothetical protein; putative dehydratase 571 3NTH5 MaoC like domain I METABOLISM Lipid transport and metabolism ACIAD1976 CDS -3 1964661 1966061 no putative short-chain dehydrogenase 881 3NIXI KR domain I METABOLISM Lipid transport and metabolism ACIAD1976 CDS -3 1964661 1966061 no putative short-chain dehydrogenase 881 3NIXI KR domain Q METABOLISM Secondary metabolites biosynthesis, transport and catabolism ACIAD1977 CDS +1 1966552 1967832 no putative acyl-CoA thiolase 825 3NK5Q Belongs to the thiolase family I METABOLISM Lipid transport and metabolism ACIAD1978 CDS -2 1967881 1968285 no conserved hypothetical protein; putative membrane protein 261 3NTH3 Chlorhexidine efflux transporter S POORLY CHARACTERIZED Function unknown ACIAD1979 CDS +1 1968436 1969287 no putative transcriptional regulator (LysR family) 556 3NT4N LysR substrate binding domain K INFORMATION STORAGE AND PROCESSING Transcription ACIAD1980 CDS +1 1969360 1970349 no tal transaldolase 629 3NJ4Q Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway H METABOLISM Coenzyme transport and metabolism ACIAD1981 CDS +2 1970423 1971073 no putative transport protein 412 3NT7G LysE type translocator E METABOLISM Amino acid transport and metabolism ACIAD1982 CDS +2 1971185 1972360 no putative benzoate membrane transport protein 769 3NKBX Benzoate membrane transport protein Q METABOLISM Secondary metabolites biosynthesis, transport and catabolism ACIAD1983 CDS -3 1972389 1973111 no putative transporter transmembrane protein (magnesium transporter) 450 3NJC1 MgtC family S POORLY CHARACTERIZED Function unknown ACIAD1984 CDS -2 1973119 1975881 no mgtA P-type ATPase, Mg2+ ATPase transporter 1779 3NKDV Cation transporter/ATPase, N-terminus P METABOLISM Inorganic ion transport and metabolism ACIAD1985 CDS -2 1975981 1976673 no conserved hypothetical protein 467 3NMJY S POORLY CHARACTERIZED Function unknown ACIAD1986 CDS -3 1976967 1977410 no conserved hypothetical protein; putative membrane protein 304 3NNC2 RDD family S POORLY CHARACTERIZED Function unknown ACIAD1987 CDS -1 1977554 1978351 no map methionine aminopeptidase 540 3NJZD Metallopeptidase family M24 E METABOLISM Amino acid transport and metabolism ACIAD1988 CDS +2 1978697 1980016 no braZ branched chain amino acid transporter 816 3NK1Q Component of the transport system for branched-chain amino acids U CELLULAR PROCESSES AND SIGNALING Intracellular trafficking, secretion, and vesicular transport ACIAD1989 CDS +2 1980530 1980700 no conserved hypothetical protein; putative membrane protein 117 3NPH0 S POORLY CHARACTERIZED Function unknown ACIAD1990 CDS +2 1981187 1984039 no fruB phosphotransferase system, fructose-specific EI/HPr/EIIA components 1825 3NMAE Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2 G METABOLISM Carbohydrate transport and metabolism ACIAD1992 CDS +1 1984045 1984977 no fruK 1-phosphofructokinase 603 3NK3F Belongs to the carbohydrate kinase PfkB family H METABOLISM Coenzyme transport and metabolism ACIAD1993 CDS +2 1984979 1986706 no fruA phosphotransferase system, fructose-specific IIBC component 1005 3NKT3 Phosphotransferase system, EIIC G METABOLISM Carbohydrate transport and metabolism ACIAD1995 CDS +3 1986873 1987421 no conserved hypothetical protein 378 3NMAK Tyrosine phosphatase family T CELLULAR PROCESSES AND SIGNALING Signal transduction mechanisms ACIAD1996 CDS -1 1987409 1987900 no ispF 2C-methyl-D-erythritol 2,4-cyclodiphosphate synthase 317 3NKQT Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4- diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP) I METABOLISM Lipid transport and metabolism ACIAD1997 CDS +3 1987998 1988648 no conserved hypothetical protein; putative signal peptide 444 3NJCG S POORLY CHARACTERIZED Function unknown ACIAD1998 CDS -2 1988686 1989981 no dadA D-amino acid dehydrogenase, small subunit 885 3NK3Z FAD dependent oxidoreductase E METABOLISM Amino acid transport and metabolism ACIAD1999 CDS -2 1990312 1991031 no ispD 2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase 468 3NKAP Catalyzes the formation of 4-diphosphocytidyl-2-C- methyl-D-erythritol from CTP and 2-C-methyl-D-erythritol 4- phosphate (MEP) I METABOLISM Lipid transport and metabolism ACIAD2000 CDS -1 1990997 1991329 no putative cell division protein (FtsB-like) 219 3NNH4 Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic D CELLULAR PROCESSES AND SIGNALING Cell cycle control, cell division, chromosome partitioning ACIAD2001 CDS -1 1991399 1992694 no eno enolase 828 3NK1I Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis G METABOLISM Carbohydrate transport and metabolism ACIAD2002 CDS -1 1992734 1993591 no kdsA 2-dehydro-3-deoxyphosphooctonate aldolase 570 3NIHT Belongs to the KdsA family M CELLULAR PROCESSES AND SIGNALING Cell wall/membrane/envelope biogenesis ACIAD2003 CDS -1 1993619 1995256 no pyrG CTP synthase 1075 3NIZ5 Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates F METABOLISM Nucleotide transport and metabolism ACIAD2004 CDS +3 1995483 1995920 no conserved hypothetical protein; putative signal peptide 242 3NPEY S POORLY CHARACTERIZED Function unknown ACIAD2005 CDS +2 1996139 1996582 no putative universal stress protein 283 3NNAM Universal stress protein family T CELLULAR PROCESSES AND SIGNALING Signal transduction mechanisms ACIAD2006 CDS -2 1996765 1997091 no hypothetical protein 224 3NQI2 S POORLY CHARACTERIZED Function unknown ACIAD2007 CDS -3 1997718 1998152 no conserved hypothetical protein; putative hemolysin 293 3NNHF Domain of unknown function (DUF333) S POORLY CHARACTERIZED Function unknown ACIAD2008 CDS -3 1998273 2000882 no pepN aminopeptidase N 1763 3NINW Domain of unknown function (DUF3458_C) ARM repeats E METABOLISM Amino acid transport and metabolism ACIAD2009 CDS +2 2001227 2001484 no conserved hypothetical protein 171 3NPIT S POORLY CHARACTERIZED Function unknown ACIAD2010 CDS +2 2001641 2002804 no conserved hypothetical protein 794 3NJT8 S POORLY CHARACTERIZED Function unknown ACIAD2011 CDS +2 2002829 2003653 no thiM hydoxyethylthiazole kinase 537 3NJ79 Catalyzes the phosphorylation of the hydroxyl group of 4-methyl-5-beta-hydroxyethylthiazole (THZ) H METABOLISM Coenzyme transport and metabolism ACIAD2012 CDS -1 2003714 2004565 no putative transcriptional regulator (AraC family) 583 3NIQG Bacterial transcription activator, effector binding domain K INFORMATION STORAGE AND PROCESSING Transcription ACIAD2013 CDS -3 2004627 2004998 no putative 5-carboxymethyl-2-hydroxymuconate delta isomerase 242 3NNMG 5-carboxymethyl-2-hydroxymuconate isomerase E METABOLISM Amino acid transport and metabolism ACIAD2014 CDS -2 2005012 2006724 no putative helicase 1111 3NIRC Helix-turn-helix domain L INFORMATION STORAGE AND PROCESSING Replication, recombination and repair ACIAD2015 CDS +1 2006956 2008128 no putative alcohol dehydrogenase 772 3NIGY alcohol dehydrogenase C METABOLISM Energy production and conversion ACIAD2016 CDS +2 2008307 2009257 no conserved hypothetical protein; putative enzyme 639 3NJZW Serine aminopeptidase, S33 I METABOLISM Lipid transport and metabolism ACIAD2017 CDS -3 2009265 2010446 no putative transcriptional regulator 764 3NJP1 Transcriptional regulator K INFORMATION STORAGE AND PROCESSING Transcription ACIAD2017 CDS -3 2009265 2010446 no putative transcriptional regulator 764 3NJP1 Transcriptional regulator Q METABOLISM Secondary metabolites biosynthesis, transport and catabolism ACIAD2018 CDS +3 2010606 2012117 no acoD Acetaldehyde dehydrogenase 2 (Acetaldehyde dehydrogenase II) (ACDH-II) 1026 3NIN2 Involved in the biosynthesis of the osmoprotectant glycine betaine. Catalyzes the reversible oxidation of betaine aldehyde to the corresponding acid C METABOLISM Energy production and conversion ACIAD2019 CDS +1 2012260 2012955 no putative glutamine amidotransferase 468 3NJAH Glutamine amidotransferase class-I F METABOLISM Nucleotide transport and metabolism ACIAD2020 CDS -2 2012983 2013186 no hypothetical protein 51.2 3NN7D Glutathione-dependent formaldehyde-activating enzyme S POORLY CHARACTERIZED Function unknown ACIAD2021 CDS -1 2013296 2013523 no conserved hypothetical protein 144 3NPA7 S POORLY CHARACTERIZED Function unknown ACIAD2022 CDS +2 2013719 2014549 no putative transcriptional regulator (AraC/XylS family) 560 3NJBP AraC-like ligand binding domain K INFORMATION STORAGE AND PROCESSING Transcription ACIAD2023 CDS +2 2014625 2015329 no putative branched-chain amino acid transport protein (AzlC) 432 3NSUP AzlC protein E METABOLISM Amino acid transport and metabolism ACIAD2024 CDS +1 2015302 2015643 no conserved hypothetical protein; putative membrane protein 227 3NNY9 Branched-chain amino acid transport protein (AzlD) S POORLY CHARACTERIZED Function unknown ACIAD2025 CDS +3 2015814 2016311 no conserved hypothetical protein; putative signal peptide 326 3NNQK response to hydrogen peroxide S POORLY CHARACTERIZED Function unknown ACIAD2026 CDS +2 2016482 2017552 no putative choloylglycine hydrolase protein 711 3NJE7 Linear amide C-N hydrolases, choloylglycine hydrolase family M CELLULAR PROCESSES AND SIGNALING Cell wall/membrane/envelope biogenesis ACIAD2027 CDS +3 2017596 2018087 no conserved hypothetical protein 335 3NP79 S POORLY CHARACTERIZED Function unknown ACIAD2028 CDS -1 2018141 2019232 no aroC chorismate synthase 720 3NIIB Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system E METABOLISM Amino acid transport and metabolism ACIAD2029 CDS -1 2019245 2020255 no putative adenine-specific methylase 661 3NIW2 Specifically methylates the 50S ribosomal protein L3 on a specific glutamine residue J INFORMATION STORAGE AND PROCESSING Translation, ribosomal structure and biogenesis ACIAD2031 CDS -1 2020514 2021359 no conserved hypothetical protein 535 3NK4R S POORLY CHARACTERIZED Function unknown ACIAD2032 CDS +3 2021646 2023067 no putative bifunctional protein [Includes: putative transcriptional regulator (GntR family); putative amino transferase] 946 3NIZN helix_turn_helix gluconate operon transcriptional repressor K INFORMATION STORAGE AND PROCESSING Transcription ACIAD2034 CDS -3 2023161 2023742 no conserved hypothetical protein; putative signal peptide 376 3NIYX YceI-like domain S POORLY CHARACTERIZED Function unknown ACIAD2035 CDS -1 2024042 2026030 no tkt transketolase 1330 3NJYU Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate G METABOLISM Carbohydrate transport and metabolism ACIAD2037 CDS +2 2026565 2027731 no metK methionine adenosyltransferase 750 3NJFZ Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme H METABOLISM Coenzyme transport and metabolism ACIAD2038 CDS -3 2027805 2028056 no hypothetical protein 183 3NP0R S POORLY CHARACTERIZED Function unknown ACIAD2039 CDS +3 2028276 2028467 no hypothetical protein 122 3NQ8V S POORLY CHARACTERIZED Function unknown ACIAD2040 CDS -1 2028566 2029132 no putative suppressor of F exclusion of phage T7 (FxsA) 309 3NKSY FxsA cytoplasmic membrane protein S POORLY CHARACTERIZED Function unknown ACIAD2041 CDS +1 2029228 2029803 no ruvC holliday junction nuclease 356 3NJUP Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group L INFORMATION STORAGE AND PROCESSING Replication, recombination and repair ACIAD2042 CDS -3 2029809 2031281 no conserved hypothetical protein; putative membrane protein 974 3NJ6K Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration G METABOLISM Carbohydrate transport and metabolism ACIAD2043 CDS +3 2031282 2032412 no conserved hypothetical protein; putative ferredoxin 769 3NJ0V Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr) C METABOLISM Energy production and conversion ACIAD2045 CDS +3 2032479 2033492 no bioB biotin synthetase 662 3NJJH Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism H METABOLISM Coenzyme transport and metabolism ACIAD2046 CDS -3 2033535 2033747 no conserved hypothetical protein 143 3NPCH S POORLY CHARACTERIZED Function unknown ACIAD2048 CDS +1 2035753 2036298 no putative bacterioferritin (cytochrome b1) 348 3NQYH Rubrerythrin P METABOLISM Inorganic ion transport and metabolism ACIAD2049 CDS +3 2036574 2038742 no putative ferric siderophore receptor protein 1429 3NJY9 TonB dependent receptor P METABOLISM Inorganic ion transport and metabolism ACIAD2050 CDS +1 2039140 2039688 no putative acyltransferase 361 3NJBS Phosphate acyltransferases I METABOLISM Lipid transport and metabolism ACIAD2052 CDS +1 2039854 2040603 no putative transcriptional regulator (YebC like) 466 3NKV6 transcriptional regulatory protein K INFORMATION STORAGE AND PROCESSING Transcription ACIAD2053 CDS -3 2040648 2041121 no putative transcriptional regulator 305 3NKR0 Lrp/AsnC ligand binding domain K INFORMATION STORAGE AND PROCESSING Transcription ACIAD2054 CDS +2 2041532 2042944 no conserved hypothetical protein; putative protein (DcaP-like) 912 3NTMQ Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane S POORLY CHARACTERIZED Function unknown ACIAD2056 CDS -3 2043270 2044013 no gltL glutamate/aspartate transport protein (ABC superfamily, atp_bind) 498 3NIF3 ABC transporter E METABOLISM Amino acid transport and metabolism ACIAD2058 CDS -1 2044028 2044705 no gltK glutamate/aspartate transport protein (ABC superfamily, membrane) 426 3NSMI Binding-protein-dependent transport system inner membrane component P METABOLISM Inorganic ion transport and metabolism ACIAD2059 CDS -2 2044708 2045409 no gltJ glutamate/aspartate transport protein (ABC superfamily, membrane) 448 3NSMP Binding-protein-dependent transport system inner membrane component E METABOLISM Amino acid transport and metabolism ACIAD2061 CDS -3 2045652 2046545 no gltI glutamate/aspartate transport protein (ABC superfamily, peri_bind) 583 3NK0B Bacterial periplasmic substrate-binding proteins E METABOLISM Amino acid transport and metabolism ACIAD2061 CDS -3 2045652 2046545 no gltI glutamate/aspartate transport protein (ABC superfamily, peri_bind) 583 3NK0B Bacterial periplasmic substrate-binding proteins T CELLULAR PROCESSES AND SIGNALING Signal transduction mechanisms ACIAD2062 CDS -2 2047156 2047926 no putative glutathione S-transferase 514 3NJB0 Glutathione S-transferase, N-terminal domain O CELLULAR PROCESSES AND SIGNALING Posttranslational modification, protein turnover, chaperones ACIAD2064 CDS +3 2048256 2049491 no putative Acyl-CoA dehydrogenase 798 3NIVE Acyl-CoA dehydrogenase, C-terminal domain I METABOLISM Lipid transport and metabolism ACIAD2065 CDS +1 2049469 2050737 no putative acyl-CoA dehydrogenase 815 3NMB7 Acyl-CoA dehydrogenase, C-terminal domain I METABOLISM Lipid transport and metabolism ACIAD2066 CDS +3 2050737 2052149 no putative monooxygenase (DszA-like) 951 3NISQ Luciferase-like monooxygenase C METABOLISM Energy production and conversion ACIAD2068 CDS +3 2052165 2052998 no metQ D-methionine transport protein (ABC superfamily, peri_bind) 556 3NJG3 NLPA lipoprotein P METABOLISM Inorganic ion transport and metabolism ACIAD2069 CDS +1 2053021 2054091 no metN D- and L-methionine transport protein (ABC superfamily, atp_bind) 698 3NJ9Q Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system P METABOLISM Inorganic ion transport and metabolism ACIAD2070 CDS +2 2054072 2054731 no metI D- and L-methionine transport protein (ABC superfamily, membrane) 412 3NJRF Binding-protein-dependent transport system inner membrane component P METABOLISM Inorganic ion transport and metabolism ACIAD2071 CDS +2 2054819 2055922 no putative GTP-binding protein 716 3NJ4G ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner J INFORMATION STORAGE AND PROCESSING Translation, ribosomal structure and biogenesis ACIAD2072 CDS +3 2056089 2056700 no sodM superoxide dismutase [Mn] 422 3NKXI Destroys radicals which are normally produced within the cells and which are toxic to biological systems P METABOLISM Inorganic ion transport and metabolism ACIAD2074 CDS +1 2057053 2057280 no conserved hypothetical protein; putative signal peptide 139 3NP1B S POORLY CHARACTERIZED Function unknown ACIAD2075 CDS -2 2057344 2057760 no conserved hypothetical protein 281 3NNSE S POORLY CHARACTERIZED Function unknown ACIAD2077 CDS +2 2058008 2058397 no conserved hypothetical protein 258 3NP2Y Tautomerase enzyme S POORLY CHARACTERIZED Function unknown ACIAD2078 CDS +1 2058547 2059761 no purT phosphoribosylglycinamide formyltransferase 2 783 3NIGI Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate F METABOLISM Nucleotide transport and metabolism ACIAD2079 CDS +1 2059783 2062449 no glnD uridylyltransferase 1763 3NM3J Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen O CELLULAR PROCESSES AND SIGNALING Posttranslational modification, protein turnover, chaperones ACIAD2080 CDS +3 2062476 2063645 no dapC succinyldiaminopimelate transaminase 793 3NJ97 Aminotransferase class I and II E METABOLISM Amino acid transport and metabolism ACIAD2081 CDS -2 2063713 2064123 no conserved hypothetical protein; putative membrane protein 274 3NQ6B Nickel/cobalt transporter regulator S POORLY CHARACTERIZED Function unknown ACIAD2082 CDS -1 2064281 2066497 no putative ferric siderophore receptor protein 1452 3NTMR TonB dependent receptor P METABOLISM Inorganic ion transport and metabolism ACIAD2083 CDS -3 2066652 2067257 no putative amino acid efflux protein, putative threonine efflux protein 389 3NP6X LysE type translocator E METABOLISM Amino acid transport and metabolism ACIAD2084 CDS -1 2067308 2068153 no putative transcriptional regulator (AraC family) 567 3NK70 AraC-like ligand binding domain K INFORMATION STORAGE AND PROCESSING Transcription ACIAD2085 CDS -3 2068191 2068673 no gpo glutathione peroxidase 329 3NIHD Belongs to the glutathione peroxidase family O CELLULAR PROCESSES AND SIGNALING Posttranslational modification, protein turnover, chaperones ACIAD2086 CDS -1 2068670 2069089 no msrB peptide methionine sulfoxide reductase 303 3NN4E Belongs to the MsrB Met sulfoxide reductase family O CELLULAR PROCESSES AND SIGNALING Posttranslational modification, protein turnover, chaperones ACIAD2087 CDS +2 2069321 2070751 no AlaA glutamate-pyruvate aminotransferase 963 3NJ6Z Aminotransferase E METABOLISM Amino acid transport and metabolism ACIAD2088 CDS +3 2071101 2072168 no aspQ glutaminase-asparaginase 680 3NKAE Asparaginase E METABOLISM Amino acid transport and metabolism ACIAD2088 CDS +3 2071101 2072168 no aspQ glutaminase-asparaginase 680 3NKAE Asparaginase J INFORMATION STORAGE AND PROCESSING Translation, ribosomal structure and biogenesis ACIAD2089 CDS +2 2072315 2075878 no dnaE DNA polymerase III, alpha chain 2322 3NIGC DNA polymerase L INFORMATION STORAGE AND PROCESSING Replication, recombination and repair ACIAD2090 CDS +3 2075934 2076749 no TrmJ tRNA (cytidine/uridine-2'-O-)-methyltransferase 526 3NJAD Catalyzes the formation of 2'O-methylated cytidine (Cm32) or 2'O-methylated uridine (Um32) at position 32 in tRNA J INFORMATION STORAGE AND PROCESSING Translation, ribosomal structure and biogenesis ACIAD2091 CDS +1 2076742 2077551 no cysE serine acetyltransferase 531 3NJAM Serine acetyltransferase, N-terminal E METABOLISM Amino acid transport and metabolism ACIAD2092 CDS +2 2077625 2078590 no conserved hypothetical protein 630 3NJWX Tetratricopeptide repeat S POORLY CHARACTERIZED Function unknown ACIAD2094 CDS +2 2078801 2080723 no conserved hypothetical protein 1255 3NIGP Alpha beta hydrolase S POORLY CHARACTERIZED Function unknown ACIAD2095 CDS -3 2080761 2081528 no conserved hypothetical protein 533 3NKIK Iron-containing redox enzyme H METABOLISM Coenzyme transport and metabolism ACIAD2096 CDS +3 2081967 2083199 no putative GGDEF family protein 795 3NK89 diguanylate cyclase T CELLULAR PROCESSES AND SIGNALING Signal transduction mechanisms ACIAD2097 CDS +3 2083257 2084057 no conserved hypothetical protein; putative signal peptide 526 3NKHA Domain of unknown function (DUF4198) P METABOLISM Inorganic ion transport and metabolism ACIAD2098 CDS +3 2084295 2084951 no QueH Epoxyqueuosine reductase QueH 474 3NJJ1 Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr) C METABOLISM Energy production and conversion ACIAD2099 CDS -1 2085041 2085841 no putative hydrolases or acyltransferases (alpha/beta hydrolase superfamily) 536 3NT07 PGAP1-like protein S POORLY CHARACTERIZED Function unknown ACIAD2100 CDS +2 2086076 2087749 no putative permease (MFS superfamily) 1122 3NKW7 Major Facilitator Superfamily P METABOLISM Inorganic ion transport and metabolism ACIAD2101 CDS -1 2087813 2088934 no putative 3-oxoacyl-[acyl-carrier-protein] synthase III 720 3NIGQ synthase III I METABOLISM Lipid transport and metabolism ACIAD2102 CDS -1 2088950 2092804 no hrpA ATP-dependent helicase 2493 3NJVR Helicase associated domain (HA2) Add an annotation L INFORMATION STORAGE AND PROCESSING Replication, recombination and repair ACIAD2103 CDS +3 2093160 2093723 no ahpC alkyl hydroperoxide reductase, C22 subunit, thioredoxin-like (detoxification of hydroperoxides) 388 3NIQ5 Alkyl hydroperoxide reductase O CELLULAR PROCESSES AND SIGNALING Posttranslational modification, protein turnover, chaperones ACIAD2104 CDS -3 2094267 2095049 no putative oxidoreductase, short-chain dehydrogenase/reductase family 500 3NKBT KR domain S POORLY CHARACTERIZED Function unknown ACIAD2105 CDS -2 2095069 2095737 no conserved hypothetical protein 443 3NNR8 Iron-containing redox enzyme K INFORMATION STORAGE AND PROCESSING Transcription ACIAD2106 CDS -2 2095750 2097201 no putative Long-chain-fatty-acid-CoA ligase 957 3NKBQ AMP-binding enzyme I METABOLISM Lipid transport and metabolism ACIAD2107 CDS -1 2097191 2097877 no conserved hypothetical protein 469 3NN6C Thermostable hemolysin S POORLY CHARACTERIZED Function unknown ACIAD2108 CDS +2 2098247 2098609 no conserved hypothetical protein 259 3NSQY Protein of unknown function (DUF861) S POORLY CHARACTERIZED Function unknown ACIAD2109 CDS -3 2098674 2099018 no conserved hypothetical protein; putative membrane protein 191 3NPHI S POORLY CHARACTERIZED Function unknown ACIAD2110 CDS +3 2099628 2100095 no BLUF domain protein 319 3NTMS Sensors of blue-light using FAD S POORLY CHARACTERIZED Function unknown ACIAD2111 CDS -3 2100099 2100359 no conserved hypothetical protein 180 3NQFE S POORLY CHARACTERIZED Function unknown ACIAD2113 CDS +2 2100866 2101435 no conserved hypothetical protein 369 3NKY2 Domain of unknown function (DUF4385) S POORLY CHARACTERIZED Function unknown ACIAD2114 CDS -3 2101515 2101964 no conserved hypothetical protein 291 3NPTQ S POORLY CHARACTERIZED Function unknown ACIAD2115 CDS -2 2102110 2102241 no hypothetical protein 45.8 3NK66 EamA-like transporter family E METABOLISM Amino acid transport and metabolism ACIAD2115 CDS -2 2102110 2102241 no hypothetical protein 45.8 3NK66 EamA-like transporter family G METABOLISM Carbohydrate transport and metabolism ACIAD2116 CDS -1 2102429 2104636 no putative ferric siderophore receptor protein (bfnH) 1457 3NJU1 TonB dependent receptor P METABOLISM Inorganic ion transport and metabolism ACIAD2117 CDS -3 2104707 2105366 no putative siderophore biosynthese protein (bfnL) 450 3NSP0 Siderophore biosynthesis protein domain J INFORMATION STORAGE AND PROCESSING Translation, ribosomal structure and biogenesis ACIAD2118 CDS -2 2105332 2105958 no putative demethylmenaquinone methyltransferase (bfnG) 410 3NKW9 Aldolase/RraA H METABOLISM Coenzyme transport and metabolism ACIAD2119 CDS -3 2105943 2106764 no hypothetical protein 565 3NNRN FhuF 2Fe-2S C-terminal domain S POORLY CHARACTERIZED Function unknown ACIAD2120 CDS -3 2106771 2108696 no putative siderophore biosynthesis protein (bfnE) 1302 3NMS4 IucA / IucC family Q METABOLISM Secondary metabolites biosynthesis, transport and catabolism ACIAD2121 CDS -1 2108681 2110531 no putative siderophore biosynthesis protein (bfnD) 1246 3NK05 IucA / IucC family Q METABOLISM Secondary metabolites biosynthesis, transport and catabolism ACIAD2122 CDS -2 2110549 2112003 no putative multidrug resistance protein (MFS superfamily) (BfnC) 926 3NSY8 Sugar (and other) transporter E METABOLISM Amino acid transport and metabolism ACIAD2122 CDS -2 2110549 2112003 no putative multidrug resistance protein (MFS superfamily) (BfnC) 926 3NSY8 Sugar (and other) transporter G METABOLISM Carbohydrate transport and metabolism ACIAD2122 CDS -2 2110549 2112003 no putative multidrug resistance protein (MFS superfamily) (BfnC) 926 3NSY8 Sugar (and other) transporter P METABOLISM Inorganic ion transport and metabolism ACIAD2123 CDS -2 2112007 2113419 no putative lysine/ornithine N-monooxygenase (bfnB) 957 3NIYD L-lysine 6-monooxygenase (NADPH-requiring) Q METABOLISM Secondary metabolites biosynthesis, transport and catabolism ACIAD2124 CDS -1 2113412 2115208 no putative siderophore biosynthesis protein (bfnA) 1217 3NKU4 IucA / IucC family Q METABOLISM Secondary metabolites biosynthesis, transport and catabolism ACIAD2125 CDS -3 2115918 2116367 no BLUF domain protein 307 3NN0H Sensors of blue-light using FAD S POORLY CHARACTERIZED Function unknown ACIAD2126 CDS +1 2116552 2116839 no conserved hypothetical protein 197 3NPDS S POORLY CHARACTERIZED Function unknown ACIAD2129 CDS -3 2118807 2119298 no BLUF domain protein 339 3NTMT Sensors of blue-light using FAD S POORLY CHARACTERIZED Function unknown ACIAD2131 CDS +2 2119958 2120098 no hypothetical protein 94 3NN19 Belongs to the 'phage' integrase family L INFORMATION STORAGE AND PROCESSING Replication, recombination and repair ACIAD2132 CDS -2 2120608 2121240 no hypothetical protein 427 32ZR8 S POORLY CHARACTERIZED Function unknown ACIAD2133 CDS -3 2121258 2121590 no hypothetical protein; putative signal peptide 210 3NSGG S POORLY CHARACTERIZED Function unknown ACIAD2134 CDS -1 2121584 2122300 no hypothetical protein 464 3NQJW S POORLY CHARACTERIZED Function unknown ACIAD2135 CDS -2 2122555 2122806 no conserved hypothetical protein 168 3NRPA S POORLY CHARACTERIZED Function unknown ACIAD2136 CDS -3 2122803 2123123 no hypothetical protein 203 3NRRW S POORLY CHARACTERIZED Function unknown ACIAD2137 CDS -1 2123198 2123923 no putative DNA-binding protein (Roi) 476 3NKV8 Phage antirepressor protein KilAC domain S POORLY CHARACTERIZED Function unknown ACIAD2139 CDS +1 2124196 2124609 no putative phage regulatory protein 63.9 3NPYE Arc-like DNA binding domain S POORLY CHARACTERIZED Function unknown ACIAD2140 CDS -2 2124745 2125659 no hypothetical protein 601 3NQ2E S POORLY CHARACTERIZED Function unknown ACIAD2142 CDS -3 2125908 2127281 no putative hydrolase 918 1SME0 S POORLY CHARACTERIZED Function unknown ACIAD2143 CDS +1 2127544 2127819 no hypothetical protein 187 3NPDS S POORLY CHARACTERIZED Function unknown ACIAD2144 CDS +3 2128146 2128739 no putative threonine efflux protein 368 3NJKU LysE type translocator E METABOLISM Amino acid transport and metabolism ACIAD2145 CDS -3 2128812 2129357 no hypothetical protein 386 3NKPK LysM domain S POORLY CHARACTERIZED Function unknown ACIAD2146 CDS -1 2129384 2129788 no conserved hypothetical protein; putative membrane protein 253 3NNKN S POORLY CHARACTERIZED Function unknown ACIAD2148 CDS -2 2129836 2132325 no conserved hypothetical protein 1657 3NMSC Fibronectin type 3 domain S POORLY CHARACTERIZED Function unknown ACIAD2149 CDS -3 2132328 2132768 no putative cell wall-associated hydrolases (invasion-associated proteins) 314 3NN30 NlpC/P60 family M CELLULAR PROCESSES AND SIGNALING Cell wall/membrane/envelope biogenesis ACIAD2151 CDS -2 2132812 2133003 no hypothetical protein 58.5 3NSAR S POORLY CHARACTERIZED Function unknown ACIAD2152 CDS -3 2133000 2134631 no conserved hypothetical protein 436 3NPXA Mycoplasma protein of unknown function, DUF285 S POORLY CHARACTERIZED Function unknown ACIAD2153 CDS -1 2134643 2136793 no conserved hypothetical protein 1436 3NS1B CotH kinase protein S POORLY CHARACTERIZED Function unknown ACIAD2154 CDS -1 2136857 2137714 no putative phage associated protein 568 3NM5X Phage conserved hypothetical protein BR0599 S POORLY CHARACTERIZED Function unknown ACIAD2155 CDS -2 2137711 2138352 no putative phage associated protein 399 3NMVF Conserved hypothetical protein 2217 (DUF2460) S POORLY CHARACTERIZED Function unknown ACIAD2156 CDS -2 2138362 2141886 no putative phage associated protein 1973 3NKIY tail tape measure protein D CELLULAR PROCESSES AND SIGNALING Cell cycle control, cell division, chromosome partitioning ACIAD2157 CDS -3 2142009 2143055 no hypothetical protein; putative signal peptide 51.6 3NPKQ S POORLY CHARACTERIZED Function unknown ACIAD2158 CDS -2 2143129 2143377 no hypothetical protein 167 3NPZW S POORLY CHARACTERIZED Function unknown ACIAD2159 CDS -3 2143389 2143724 no putative phage associated protein 217 3NP51 S POORLY CHARACTERIZED Function unknown ACIAD2160 CDS -1 2143706 2144473 no conserved hypothetical protein 503 3NKJA S POORLY CHARACTERIZED Function unknown ACIAD2161 CDS -2 2144533 2144976 no putative phage associated protein 291 3NNJ8 S POORLY CHARACTERIZED Function unknown ACIAD2162 CDS -1 2144966 2145448 no putative phage associated protein 305 3NN32 Phage virion morphogenesis S POORLY CHARACTERIZED Function unknown ACIAD2164 CDS -3 2145660 2146040 no putative bacteriophage protein 240 3NNRD Protein of unknown function (DUF4054) S POORLY CHARACTERIZED Function unknown ACIAD2165 CDS -2 2146048 2146428 no hypothetical protein; putative signal peptide 232 3NPC7 S POORLY CHARACTERIZED Function unknown ACIAD2166 CDS -1 2146442 2147416 no putative bacteriophage protein 638 3NMTS Uncharacterized protein conserved in bacteria (DUF2184) S POORLY CHARACTERIZED Function unknown ACIAD2167 CDS -1 2147423 2147896 no conserved hypothetical protein 301 3NMSA S POORLY CHARACTERIZED Function unknown ACIAD2168 CDS -2 2147908 2149119 no putative phage-related protein 791 3NMS1 Uncharacterized protein conserved in bacteria (DUF2213) S POORLY CHARACTERIZED Function unknown ACIAD2169 CDS -2 2149174 2149470 no hypothetical protein 190 3NP3R S POORLY CHARACTERIZED Function unknown ACIAD2170 CDS -2 2149543 2150094 no putative phage anti-repressor protein 362 3NN9E AntA/AntB antirepressor K INFORMATION STORAGE AND PROCESSING Transcription ACIAD2172 CDS +2 2150390 2150647 no putative phage regulatory protein 167 3NPYE Arc-like DNA binding domain S POORLY CHARACTERIZED Function unknown ACIAD2173 CDS -2 2150656 2151375 no conserved hypothetical protein; putative bacteriophage protein 473 3NN08 Phage Mu protein F like protein S POORLY CHARACTERIZED Function unknown ACIAD2174 CDS -1 2151419 2152750 no conserved hypothetical protein; putative phage-related protein 887 3NMUE Protein of unknown function (DUF1073) S POORLY CHARACTERIZED Function unknown ACIAD2175 CDS -2 2152759 2154285 no putative terminase 1013 3NK4C Terminase RNaseH-like domain S POORLY CHARACTERIZED Function unknown ACIAD2176 CDS -1 2154263 2154739 no putative associated phage protein 303 3NNMR Uncharacterized conserved protein (DUF2280) S POORLY CHARACTERIZED Function unknown ACIAD2177 CDS -2 2154799 2155440 no conserved hypothetical protein 445 3NJ4N S POORLY CHARACTERIZED Function unknown ACIAD2178 CDS -1 2155409 2155876 no conserved hypothetical protein 319 3NNIQ Protein conserved in bacteria S POORLY CHARACTERIZED Function unknown ACIAD2179 CDS -2 2155945 2156157 no hypothetical protein; putative membrane protein 41.6 3NQGS S POORLY CHARACTERIZED Function unknown ACIAD2180 CDS -3 2156460 2156753 no hypothetical protein 196 3NQB4 S POORLY CHARACTERIZED Function unknown ACIAD2181 CDS -1 2156963 2157292 no putative proteic killer active protein 218 1SAG3 TIGRFAM addiction module antidote protein, HigA family K INFORMATION STORAGE AND PROCESSING Transcription ACIAD2182 CDS -1 2157305 2157601 no putative proteic killer suppression protein 214 3NS7P RelE-like toxin of type II toxin-antitoxin system HigB S POORLY CHARACTERIZED Function unknown ACIAD2183 CDS -1 2157677 2158579 no hypothetical protein 602 3NN6M S POORLY CHARACTERIZED Function unknown ACIAD2184 CDS -1 2158595 2159086 no conserved hypothetical protein 336 3NNNQ S POORLY CHARACTERIZED Function unknown ACIAD2185 CDS -2 2159134 2160462 no putative replicative DNA helicase 775 3NN0N DnaB-like helicase N terminal domain L INFORMATION STORAGE AND PROCESSING Replication, recombination and repair ACIAD2186 CDS -3 2160456 2161436 no hypothetical protein 649 3NMXN DnaD domain protein L INFORMATION STORAGE AND PROCESSING Replication, recombination and repair ACIAD2187 CDS -1 2161436 2161804 no hypothetical protein 79 3NQF5 S POORLY CHARACTERIZED Function unknown ACIAD2188 CDS -2 2161789 2162238 no putative bacteriophage protein (Gp55-like) 297 3NMJW Phage regulatory protein CII (CP76) S POORLY CHARACTERIZED Function unknown ACIAD2189 CDS -2 2162263 2162508 no conserved hypothetical protein 167 3NPH5 DNA-binding transcriptional regulator Cro S POORLY CHARACTERIZED Function unknown ACIAD2190 CDS +2 2162585 2163028 no putative prophage transcriptional repressor 288 COG4197 sequence-specific DNA binding S POORLY CHARACTERIZED Function unknown ACIAD2190 CDS +2 2162585 2163028 no putative prophage transcriptional repressor 288 COG4197 sequence-specific DNA binding S POORLY CHARACTERIZED Function unknown ACIAD2191 CDS +3 2163033 2164049 no conserved hypothetical protein 679 1S18Y S POORLY CHARACTERIZED Function unknown ACIAD2192 CDS +2 2164052 2165197 no conserved hypothetical protein 81.6 1S163 S POORLY CHARACTERIZED Function unknown ACIAD2193 CDS +3 2165169 2165858 no hypothetical protein 51.2 3W2I9 S POORLY CHARACTERIZED Function unknown ACIAD2194 CDS +1 2165956 2166411 no conserved hypothetical protein 298 3NNT7 S POORLY CHARACTERIZED Function unknown ACIAD2196 CDS +3 2166648 2167442 no hypothetical protein 529 3NRFD S POORLY CHARACTERIZED Function unknown ACIAD2197 CDS +2 2167439 2167849 no hypothetical protein 258 3NQB8 S POORLY CHARACTERIZED Function unknown ACIAD2199 CDS +2 2168096 2168389 no conserved hypothetical protein 195 3NPAX S POORLY CHARACTERIZED Function unknown ACIAD2200 CDS -1 2168414 2169436 no putative integrase/recombinase protein 684 3NM1I Phage integrase family L INFORMATION STORAGE AND PROCESSING Replication, recombination and repair ACIAD2201 CDS -3 2169744 2171741 no conserved hypothetical protein; putative membrane protein 1321 3NJF0 Domain of unknown function (DUF3488) E METABOLISM Amino acid transport and metabolism ACIAD2202 CDS -2 2171743 2172648 no conserved hypothetical protein; putative membrane protein 582 3NJSG Protein of unknown function DUF58 S POORLY CHARACTERIZED Function unknown ACIAD2203 CDS -3 2172666 2173562 no putative methanol dehydrogenase regulatory protein 570 3NJ90 ATPase family associated with various cellular activities (AAA) S POORLY CHARACTERIZED Function unknown ACIAD2204 CDS -3 2173698 2173934 no conserved hypothetical protein 169 3NP2X Selenoprotein, putative S POORLY CHARACTERIZED Function unknown ACIAD2205 CDS -1 2174000 2176105 no cstA starvation-induced protein involved in peptide utilization during carbon starvation 1335 3NJGU Carbon starvation protein T CELLULAR PROCESSES AND SIGNALING Signal transduction mechanisms ACIAD2206 CDS -3 2176269 2176847 no efp elongation factor P 383 3NJZR Involved in peptide bond synthesis. Alleviates ribosome stalling that occurs when 3 or more consecutive Pro residues or the sequence PPG is present in a protein, possibly by augmenting the peptidyl transferase activity of the ribosome. Modification of Lys-34 is required for alleviation J INFORMATION STORAGE AND PROCESSING Translation, ribosomal structure and biogenesis ACIAD2207 CDS +1 2176909 2177925 no putative aminomutase (kamA-like) 681 3NJDI 4Fe-4S single cluster domain C METABOLISM Energy production and conversion ACIAD2208 CDS +1 2177944 2179653 no conserved hypothetical protein 1120 3NK42 S POORLY CHARACTERIZED Function unknown ACIAD2209 CDS +1 2179678 2181771 no conserved hypothetical protein 1343 3NKMC Putative diguanylate phosphodiesterase T CELLULAR PROCESSES AND SIGNALING Signal transduction mechanisms ACIAD2210 CDS -3 2181828 2182052 no rpmE 50S ribosomal protein L31 156 3NPGX Binds the 23S rRNA J INFORMATION STORAGE AND PROCESSING Translation, ribosomal structure and biogenesis ACIAD2212 CDS -2 2182255 2183289 no putative Na+-dependent transporter 637 3NK86 SBF-like CPA transporter family (DUF4137) S POORLY CHARACTERIZED Function unknown ACIAD2213 CDS -3 2183391 2183792 no gloA lactoylglutathione lyase 274 3NN4K Catalyzes the conversion of hemimercaptal, formed from methylglyoxal and glutathione, to S-lactoylglutathione E METABOLISM Amino acid transport and metabolism ACIAD2214 CDS -1 2183795 2185987 no putative transporter 1373 3NIGX Acetyl-coenzyme A transporter 1 G METABOLISM Carbohydrate transport and metabolism ACIAD2216 CDS +2 2186165 2188792 no putative ATP-dependent protease 1662 3NJRD Belongs to the peptidase S16 family O CELLULAR PROCESSES AND SIGNALING Posttranslational modification, protein turnover, chaperones ACIAD2217 CDS -3 2188857 2189483 no conserved hypothetical protein; putative metal-dependent HD phosphohydrolase domain 420 3NIJ4 protein conserved in bacteria S POORLY CHARACTERIZED Function unknown ACIAD2218 CDS -2 2189515 2190297 no putative peroxyde stress protein 509 3NITR Belongs to the UPF0246 family S POORLY CHARACTERIZED Function unknown ACIAD2219 CDS +3 2190405 2191064 no conserved hypothetical protein; putative hydrolase 454 3NSQR Alpha/beta hydrolase family S POORLY CHARACTERIZED Function unknown ACIAD2220 CDS -2 2191174 2192637 no pepD aminoacyl-histidine dipeptidase (peptidase D) 983 3NKXC Peptidase family M20/M25/M40 E METABOLISM Amino acid transport and metabolism ACIAD2221 CDS -3 2192715 2193104 no conserved hypothetical protein 272 3NN45 S POORLY CHARACTERIZED Function unknown ACIAD2222 CDS -1 2193227 2195473 no bifunctional protein [Includes: putative prephenate or cyclohexadienyl dehydrogenase; 3-phosphoshikimate 1-carboxyvinyltransferase (5- enolpyruvylshikimate-3-phosphate synthase) (EPSP synthase) (EPSPS) (AroA)] 1447 3NK5W Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3- phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate E METABOLISM Amino acid transport and metabolism ACIAD2223 CDS -1 2195579 2196688 no pheA bifuctional protein [Includes: chorismate mutase P; prephenate dehydratase ] 712 3NJBR chorismate mutase E METABOLISM Amino acid transport and metabolism ACIAD2224 CDS +3 2196861 2197829 no putative hydrolase of the alpha/beta superfamily 649 3NMDY Putative esterase S POORLY CHARACTERIZED Function unknown ACIAD2225 CDS +3 2197968 2198519 no conserved hypothetical protein; putative intracellular proteinase 363 3NNF9 DJ-1/PfpI family S POORLY CHARACTERIZED Function unknown ACIAD2226 CDS -3 2198574 2199719 no acads3 Short-chain acyl CoA dehydrogenase 756 3NIIA Acyl-CoA dehydrogenase, C-terminal domain I METABOLISM Lipid transport and metabolism ACIAD2227 CDS -1 2199881 2201227 no dctA aerobic C4-dicarboxylate transport protein 836 3NJNC Responsible for the transport of dicarboxylates such as succinate, fumarate, and malate across the membrane U CELLULAR PROCESSES AND SIGNALING Intracellular trafficking, secretion, and vesicular transport ACIAD2229 CDS +2 2201678 2202685 no putative transferase 672 3NJHX Glycosyl transferase family, helical bundle domain E METABOLISM Amino acid transport and metabolism ACIAD2230 CDS -2 2202718 2202978 no conserved hypothetical protein 179 3NP0J Protein of unknown function (DUF1315) S POORLY CHARACTERIZED Function unknown ACIAD2231 CDS -3 2202975 2203898 no putative inorganic polyphosphate/ATP-NAD kinase (Poly(P)/ATP NAD kinase)(PpnK) 613 3NIJZ Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP H METABOLISM Coenzyme transport and metabolism ACIAD2234 CDS +2 2204321 2206720 no mrcB bifunctional protein [Includes penicillin-insensitive transglycosylase; penicillin-sensitive transpeptidase] (penicillin-binding protein 1B) 1577 3NJFY Cell wall formation. Synthesis of cross-linked peptidoglycan from the lipid intermediates. The enzyme has a penicillin-insensitive transglycosylase N-terminal domain (formation of linear glycan strands) and a penicillin-sensitive transpeptidase C-terminal domain (cross-linking of the peptide subunits) M CELLULAR PROCESSES AND SIGNALING Cell wall/membrane/envelope biogenesis ACIAD2235 CDS +3 2206731 2207312 no conserved hypothetical protein 335 3NNJP COG0457 FOG TPR repeat H METABOLISM Coenzyme transport and metabolism ACIAD2236 CDS -2 2207329 2208243 no putative bifunctional protein [Includes: dGTP-pyrophosphohydrolase; thiamine phosphate synthase] 632 3NKK2 Belongs to the Nudix hydrolase family F METABOLISM Nucleotide transport and metabolism ACIAD2236 CDS -2 2207329 2208243 no putative bifunctional protein [Includes: dGTP-pyrophosphohydrolase; thiamine phosphate synthase] 632 3NKK2 Belongs to the Nudix hydrolase family H METABOLISM Coenzyme transport and metabolism ACIAD2238 CDS -2 2208598 2209947 no putative two-component system sensor protein 862 3NK01 His Kinase A (phosphoacceptor) domain T CELLULAR PROCESSES AND SIGNALING Signal transduction mechanisms ACIAD2239 CDS -1 2209952 2210608 no putative two-component response regulator 431 3NJV3 Transcriptional regulatory protein, C terminal K INFORMATION STORAGE AND PROCESSING Transcription ACIAD2240 CDS -2 2210716 2211096 no conserved hypothetical protein; putative signal peptide 250 3NNXC Bacterial OB fold (BOF) protein S POORLY CHARACTERIZED Function unknown ACIAD2241 CDS -1 2211164 2212921 no putative secretion pathway ATPase 1154 3NJR5 Type II secretion system (T2SS), protein E, N-terminal domain N CELLULAR PROCESSES AND SIGNALING Cell motility ACIAD2241 CDS -1 2211164 2212921 no putative secretion pathway ATPase 1154 3NJR5 Type II secretion system (T2SS), protein E, N-terminal domain U CELLULAR PROCESSES AND SIGNALING Intracellular trafficking, secretion, and vesicular transport ACIAD2242 CDS +1 2213059 2213997 no putative GGDEF family protein 627 3NMRE Domain present in phytochromes and cGMP-specific phosphodiesterases. T CELLULAR PROCESSES AND SIGNALING Signal transduction mechanisms ACIAD2243 CDS -3 2213994 2214728 no conserved hypothetical protein 496 3NKKN Uncharacterised protein family UPF0066 S POORLY CHARACTERIZED Function unknown ACIAD2244 CDS +1 2214826 2215605 no fpr ferredoxin--NADP+ reductase 524 3NIFK Oxidoreductase FAD-binding domain C METABOLISM Energy production and conversion ACIAD2245 CDS -3 2215659 2216396 no putative transcriptional regulator 480 3NMG8 FCD K INFORMATION STORAGE AND PROCESSING Transcription ACIAD2246 CDS +2 2216762 2217811 no putative outer membrane porin protein precursor 697 1MWUN Outer membrane protein (Porin) M CELLULAR PROCESSES AND SIGNALING Cell wall/membrane/envelope biogenesis ACIAD2247 CDS +1 2217862 2219328 no putative permease 968 3NKA8 Permease for cytosine/purines, uracil, thiamine, allantoin F METABOLISM Nucleotide transport and metabolism ACIAD2247 CDS +1 2217862 2219328 no putative permease 968 3NKA8 Permease for cytosine/purines, uracil, thiamine, allantoin H METABOLISM Coenzyme transport and metabolism ACIAD2248 CDS +3 2219472 2220170 no hyu hydantoin-racemase 462 3NJSY Asp/Glu/Hydantoin racemase E METABOLISM Amino acid transport and metabolism ACIAD2249 CDS -1 2220290 2221114 no putative aromatic ring-opening dioxygenase 560 3NKTJ Catalytic LigB subunit of aromatic ring-opening dioxygenase S POORLY CHARACTERIZED Function unknown ACIAD2250 CDS -2 2221393 2222997 no ahpF alkyl hydroperoxide reductase subunit, FAD/NAD(P)-binding, detoxification of hydroperoxides 1034 3NJBW Alkyl hydroperoxide reductase C METABOLISM Energy production and conversion ACIAD2251 CDS -2 2223070 2223981 no hypothetical protein; putative membrane protein 574 3NJMV S POORLY CHARACTERIZED Function unknown ACIAD2252 CDS -3 2224008 2225150 no putative tellurique resistant protein (KlaB/TelA) 697 3NJ25 Toxic anion resistance protein (TelA) P METABOLISM Inorganic ion transport and metabolism ACIAD2254 CDS -1 2225150 2225941 no putative tellurium resistant protein (KlaA/kilA) 495 3NKEK S POORLY CHARACTERIZED Function unknown ACIAD2255 CDS -3 2226219 2227472 no glyA serine hydroxymethyltransferase 823 3NJDM Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism E METABOLISM Amino acid transport and metabolism ACIAD2256 CDS -1 2227628 2228848 no conserved hypothetical protein 776 3NJFE Secretory lipase S POORLY CHARACTERIZED Function unknown ACIAD2257 CDS +2 2229020 2229718 no putative DNA exonuclease X 463 3NK9K DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease L INFORMATION STORAGE AND PROCESSING Replication, recombination and repair ACIAD2259 CDS +2 2230529 2231470 no putative transport protein (ABC superfamily, atp_bind) 608 3NIXX AAA domain, putative AbiEii toxin, Type IV TA system V CELLULAR PROCESSES AND SIGNALING Defense mechanisms ACIAD2260 CDS +1 2231470 2232243 no putative transport protein (ABC superfamily, membrane) 497 3NK60 Transport permease protein V CELLULAR PROCESSES AND SIGNALING Defense mechanisms ACIAD2261 CDS +3 2232240 2233055 no queF NADPH-dependent 7-cyano-7-deazaguanine reductase (NADPH-dependent nitrile oxidoreductase) 555 3NJGM Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1) S POORLY CHARACTERIZED Function unknown ACIAD2262 CDS +1 2233078 2233731 no conserved hypothetical protein 419 3NM76 S POORLY CHARACTERIZED Function unknown ACIAD2263 CDS +3 2233917 2234996 no rodA rod shape-determining protein 699 3NJBT Peptidoglycan polymerase that is essential for cell wall elongation M CELLULAR PROCESSES AND SIGNALING Cell wall/membrane/envelope biogenesis ACIAD2264 CDS +1 2235034 2236035 no mltB membrane-bound lytic murein transglycosylase B 672 3NKMR Transglycosylase SLT domain M CELLULAR PROCESSES AND SIGNALING Cell wall/membrane/envelope biogenesis ACIAD2265 CDS +2 2236319 2236933 no putative rare lipoprotein A family (RlpA-like) 389 3NJEK Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides M CELLULAR PROCESSES AND SIGNALING Cell wall/membrane/envelope biogenesis ACIAD2266 CDS +3 2237397 2237855 no conserved hypothetical protein; putative membrane protein 301 3NN9S Protein of unknown function (DUF962) S POORLY CHARACTERIZED Function unknown ACIAD2267 CDS -2 2237878 2238360 no conserved hypothetical protein 324 3NNJN Protein of unknown function (DUF3465) Q METABOLISM Secondary metabolites biosynthesis, transport and catabolism ACIAD2268 CDS -1 2238425 2239300 no tsf protein chain elongation factor EF-Ts 526 3NJR4 Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome J INFORMATION STORAGE AND PROCESSING Translation, ribosomal structure and biogenesis ACIAD2269 CDS -1 2239436 2240185 no rpsB 30S ribosomal protein S2 485 3NIVD Belongs to the universal ribosomal protein uS2 family J INFORMATION STORAGE AND PROCESSING Translation, ribosomal structure and biogenesis ACIAD2271 CDS +3 2240454 2241218 no map methionine aminopeptidase 519 3NK8T Methionine aminopeptidase E METABOLISM Amino acid transport and metabolism ACIAD2272 CDS +3 2241417 2242544 no conserved hypothetical protein; putative outer membrane protein 743 3NIQN OmpW family M CELLULAR PROCESSES AND SIGNALING Cell wall/membrane/envelope biogenesis ACIAD2274 CDS -1 2243210 2244625 no sthA soluble pyridine nucleotide transhydrogenase (NAD(P)(+) transhydrogenase [B-specific]) 945 3NJHT Soluble pyridine nucleotide transhydrogenase C METABOLISM Energy production and conversion ACIAD2275 CDS +2 2244827 2245840 no lipA lipoate synthase 687 3NJZS Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives H METABOLISM Coenzyme transport and metabolism ACIAD2277 CDS +1 2246152 2248641 no putative acyl-CoA dehydrogenase 1645 3NJDG Domain of unknown function (DUF1974) I METABOLISM Lipid transport and metabolism ACIAD2278 CDS +3 2248728 2249117 no putative 4-carboxymuconolactone decarboxylase 262 3NN38 Carboxymuconolactone decarboxylase family S POORLY CHARACTERIZED Function unknown ACIAD2279 CDS -3 2249118 2250176 no putative diguanylate cyclase 672 3NMNN MASE2 domain T CELLULAR PROCESSES AND SIGNALING Signal transduction mechanisms ACIAD2280 CDS +3 2250672 2252186 no proP glycine/betaine transporter (MFS superfamily) 922 3NJYI Sugar (and other) transporter E METABOLISM Amino acid transport and metabolism ACIAD2280 CDS +3 2250672 2252186 no proP glycine/betaine transporter (MFS superfamily) 922 3NJYI Sugar (and other) transporter G METABOLISM Carbohydrate transport and metabolism ACIAD2280 CDS +3 2250672 2252186 no proP glycine/betaine transporter (MFS superfamily) 922 3NJYI Sugar (and other) transporter P METABOLISM Inorganic ion transport and metabolism ACIAD2281 CDS -1 2252276 2252818 no conserved hypothetical protein 362 3NKBB Peptidase C39 family S POORLY CHARACTERIZED Function unknown ACIAD2282 CDS +2 2253029 2254432 no sahH S-adenosyl-L-homocysteine hydrolase 936 3NIJA May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine H METABOLISM Coenzyme transport and metabolism ACIAD2283 CDS +2 2254505 2255341 no metF 5,10-methylenetetrahydrofolate reductase 565 3NK2Z Methylenetetrahydrofolate reductase E METABOLISM Amino acid transport and metabolism ACIAD2284 CDS +3 2255364 2256095 no putative ribosomal RNA small subunit methyltransferase E (rsmE) 486 3NIW8 Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit J INFORMATION STORAGE AND PROCESSING Translation, ribosomal structure and biogenesis ACIAD2287 CDS +2 2257214 2259484 no maeB NAD(P)-dependent malic enzyme ; bifunctional: NADP-dependent malic oxidoreductase (N-terminal); phosphotransacetylase (C-terminal)] 1465 3NJCT Malic enzyme, NAD binding domain C METABOLISM Energy production and conversion ACIAD2288 CDS +2 2259572 2260813 no cca Multifunctional protein [Includes: CCA-adding enzyme ; 2'-nucleotidase ; 2',3'-cyclic phosphodiesterase ; Phosphatase] 832 3NK6J Catalyzes the addition and repair of the essential 3'- terminal CCA sequence in tRNAs without using a nucleic acid template. Adds these three nucleotides in the order of C, C, and A to the tRNA nucleotide-73, using CTP and ATP as substrates and producing inorganic pyrophosphate J INFORMATION STORAGE AND PROCESSING Translation, ribosomal structure and biogenesis ACIAD2290 CDS +1 2261674 2263263 no cydA cytochrome d terminal oxidase, polypeptide subunit I 1035 3NK2C oxidase, subunit C METABOLISM Energy production and conversion ACIAD2291 CDS +3 2263260 2264405 no cydB cytochrome d terminal oxidase polypeptide subunit II 758 3NJ1G oxidase, subunit C METABOLISM Energy production and conversion ACIAD2292 CDS +3 2264469 2264828 no conserved hypothetical protein; putative membrane protein 234 3NNXV Cyd operon protein YbgE (Cyd_oper_YbgE) S POORLY CHARACTERIZED Function unknown ACIAD2293 CDS -1 2264846 2265394 no putative acetyltransferase 366 3NSM7 Acetyltransferase (GNAT) domain K INFORMATION STORAGE AND PROCESSING Transcription ACIAD2294 CDS -2 2265475 2266125 no conserved hypothetical protein; putative signal peptide 420 3NKRX Belongs to the UPF0319 family S POORLY CHARACTERIZED Function unknown ACIAD2295 CDS -1 2266331 2266927 no conserved hypothetical protein; putative oxidoreductase related to nitroreductase 394 3NIPQ Nitroreductase family S POORLY CHARACTERIZED Function unknown ACIAD2296 CDS -3 2267121 2268242 no ftsY cell division protein 687 3NJ2A Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC). Interaction with SRP-RNC leads to the transfer of the RNC complex to the Sec translocase for insertion into the membrane, the hydrolysis of GTP by both Ffh and FtsY, and the dissociation of the SRP-FtsY complex into the individual components U CELLULAR PROCESSES AND SIGNALING Intracellular trafficking, secretion, and vesicular transport ACIAD2298 CDS +1 2268424 2269812 no putative zinc protease 915 3NT4F Belongs to the peptidase M16 family S POORLY CHARACTERIZED Function unknown ACIAD2299 CDS +3 2269827 2271317 no putative Zinc protease; putative signal peptide 961 3NM88 Insulinase (Peptidase family M16) S POORLY CHARACTERIZED Function unknown ACIAD2300 CDS -1 2271314 2271649 no conserved hypothetical protein 211 3NPYS S POORLY CHARACTERIZED Function unknown ACIAD2301 CDS -3 2271762 2272121 no conserved hypothetical protein 234 3NP1P S POORLY CHARACTERIZED Function unknown ACIAD2302 CDS +2 2272343 2272576 no conserved hypothetical protein 151 3NPA1 S POORLY CHARACTERIZED Function unknown ACIAD2303 CDS +2 2272703 2273077 no conserved hypothetical protein 266 3NN4X Protein of unknown function (DUF2750) S POORLY CHARACTERIZED Function unknown ACIAD2305 CDS +1 2273212 2273643 no conserved hypothetical protein 272 3NNMS Domain in cystathionine beta-synthase and other proteins. S POORLY CHARACTERIZED Function unknown ACIAD2306 CDS -3 2273784 2274971 no conserved hypothetical protein 792 3NIG2 VWA domain containing CoxE-like protein S POORLY CHARACTERIZED Function unknown ACIAD2307 CDS -3 2274984 2275835 no conserved hypothetical protein; putative ATPase 567 3NJXH AAA domain (Cdc48 subfamily) S POORLY CHARACTERIZED Function unknown ACIAD2308 CDS -3 2275857 2276243 no conserved hypothetical protein; putative membrane protein 254 3NNXZ S POORLY CHARACTERIZED Function unknown ACIAD2309 CDS -2 2276236 2276556 no conserved hypothetical protein 220 3NNZ7 YcgL domain S POORLY CHARACTERIZED Function unknown ACIAD2310 CDS -1 2276630 2277826 no rnd ribonuclease D, processes tRNA 796 3NJ9N HRDC domain J INFORMATION STORAGE AND PROCESSING Translation, ribosomal structure and biogenesis ACIAD2312 CDS -2 2278015 2278611 no recR recombination protein, gap repair 395 3NKAI May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO L INFORMATION STORAGE AND PROCESSING Replication, recombination and repair ACIAD2313 CDS -1 2278625 2278957 no putative nucleoid-associated protein (YbaB like) 202 3NNGY Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection S POORLY CHARACTERIZED Function unknown ACIAD2314 CDS -3 2278989 2280179 no metZ o-acylhomoserine sulfhydrylase 777 3NIQC Catalyzes the formation of L-homocysteine from O- succinyl-L-homoserine (OSHS) and hydrogen sulfide E METABOLISM Amino acid transport and metabolism ACIAD2315 CDS +2 2280314 2281417 no putative poly(R)-hydroxyalkanoic acid synthase 732 3NK56 alpha/beta hydrolase fold I METABOLISM Lipid transport and metabolism ACIAD2316 CDS +2 2281421 2282293 no putative 3-hydroxyisobutyrate dehydrogenase 568 3NJ1Y NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase I METABOLISM Lipid transport and metabolism ACIAD2317 CDS +1 2282380 2282649 no conserved hypothetical protein; putative signal peptide 181 3NPDB YARHG S POORLY CHARACTERIZED Function unknown ACIAD2318 CDS +2 2282675 2283088 no putative histidine triad family protein 263 3NN34 Scavenger mRNA decapping enzyme C-term binding F METABOLISM Nucleotide transport and metabolism ACIAD2318 CDS +2 2282675 2283088 no putative histidine triad family protein 263 3NN34 Scavenger mRNA decapping enzyme C-term binding G METABOLISM Carbohydrate transport and metabolism ACIAD2319 CDS +3 2283333 2284439 no putative porin precursor 715 3NJDS Gram-negative porin M CELLULAR PROCESSES AND SIGNALING Cell wall/membrane/envelope biogenesis ACIAD2320 CDS -2 2284483 2285112 no conserved hypothetical protein 351 3NJZK Bacterial protein of unknown function (DUF937) S POORLY CHARACTERIZED Function unknown ACIAD2322 CDS -1 2285219 2285680 no conserved hypothetical protein 314 3NNCK S POORLY CHARACTERIZED Function unknown ACIAD2323 CDS +1 2285710 2286582 no conserved hypothetical protein 590 3NKJ2 Protein of unknown function (DUF2797) S POORLY CHARACTERIZED Function unknown ACIAD2324 CDS -1 2286617 2287807 no lpxB lipid A-disaccharide synthase 768 3NKDW Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell M CELLULAR PROCESSES AND SIGNALING Cell wall/membrane/envelope biogenesis ACIAD2325 CDS +1 2287975 2290173 no putative ferric siderophore receptor protein 1460 3NIRU TonB dependent receptor P METABOLISM Inorganic ion transport and metabolism ACIAD2327 CDS +2 2290532 2292094 no conserved hypothetical protein; putative membrane protein 1023 3NJWJ PepSY-associated TM region S POORLY CHARACTERIZED Function unknown ACIAD2328 CDS +1 2292091 2292402 no conserved hypothetical protein; putative membrane protein 206 3NPXH S POORLY CHARACTERIZED Function unknown ACIAD2329 CDS +2 2292524 2293399 no conserved hypothetical protein; putative membrane protein 550 3NJEI Sulfite exporter TauE/SafE S POORLY CHARACTERIZED Function unknown ACIAD2330 CDS +1 2293501 2294613 no aro phospho-2-dehydro-3-deoxyheptonate aldolase 731 3NIZR Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP) E METABOLISM Amino acid transport and metabolism ACIAD2331 CDS -1 2294672 2296201 no putative membrane protein 959 3NIPV Transporter associated domain P METABOLISM Inorganic ion transport and metabolism ACIAD2333 CDS +3 2296812 2297276 no putative transcriptional repressor of for multidrug resistance pump (MarR family) 303 3NN6Q helix_turn_helix multiple antibiotic resistance protein K INFORMATION STORAGE AND PROCESSING Transcription ACIAD2334 CDS -1 2297273 2297941 no conserved hypothetical protein 465 3NJKX Belongs to the SOS response-associated peptidase family S POORLY CHARACTERIZED Function unknown ACIAD2335 CDS -1 2298287 2300449 no glcB malate synthase G 1431 3NJXI Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA C METABOLISM Energy production and conversion ACIAD2336 CDS -2 2300800 2301942 no putative ATPase 747 3NIIZ Reduces the stability of FtsZ polymers in the presence of ATP D CELLULAR PROCESSES AND SIGNALING Cell cycle control, cell division, chromosome partitioning ACIAD2338 CDS -3 2302032 2303042 no putative transcriptional regulator 664 3NT38 Arabinose-binding domain of AraC transcription regulator, N-term K INFORMATION STORAGE AND PROCESSING Transcription ACIAD2339 CDS +1 2303197 2304708 no putative flavin-binding monooxygenase 1028 3NIHC Flavin-binding monooxygenase-like P METABOLISM Inorganic ion transport and metabolism ACIAD2340 CDS +2 2304884 2305663 no conserved hypothetical protein; putative membrane protein 484 3NK82 Lysine exporter LysO S POORLY CHARACTERIZED Function unknown ACIAD2341 CDS -2 2305660 2306343 no pyrF orotidine-5'-phosphate decarboxylase (OMP decarboxylase) (OMPDCase) (OMPdecase) 446 3NKE2 Catalyzes the decarboxylation of orotidine 5'- monophosphate (OMP) to uridine 5'-monophosphate (UMP) F METABOLISM Nucleotide transport and metabolism ACIAD2342 CDS -1 2306456 2307004 no conserved hypothetical protein; putative transcriptional regulator 357 3NKAG Cro/C1-type HTH DNA-binding domain K INFORMATION STORAGE AND PROCESSING Transcription ACIAD2343 CDS +3 2307075 2307743 no conserved hypothetical protein; putative branched-chain amino acid permease (azaleucine resistance) 424 3NK0M AzlC protein E METABOLISM Amino acid transport and metabolism ACIAD2344 CDS +1 2307781 2308071 no conserved hypothetical protein; putative membrane protein 174 3NPRQ Branched-chain amino acid transport protein (AzlD) S POORLY CHARACTERIZED Function unknown ACIAD2345 CDS -1 2308145 2308510 no conserved hypothetical protein; putative membrane protein 201 3NNI3 Lipopolysaccharide assembly protein A domain S POORLY CHARACTERIZED Function unknown ACIAD2346 CDS -3 2308539 2308844 no himD integration host factor (IHF),beta subunit, site specific recombination 202 3NNXJ This protein is one of the two subunits of integration host factor, a specific DNA-binding protein that functions in genetic recombination as well as in transcriptional and translational control K INFORMATION STORAGE AND PROCESSING Transcription ACIAD2347 CDS -2 2309002 2310675 no rpsA 30S ribosomal protein S1 1062 3NM5D thus facilitating recognition of the initiation point. It is needed to translate mRNA with a short Shine-Dalgarno (SD) purine-rich sequence J INFORMATION STORAGE AND PROCESSING Translation, ribosomal structure and biogenesis ACIAD2348 CDS -1 2310788 2311471 no cmk cytidylate kinase (cytidine monophosphate (CMP) kinase) 435 3NKW2 Belongs to the cytidylate kinase family. Type 1 subfamily F METABOLISM Nucleotide transport and metabolism ACIAD2349 CDS -3 2311482 2311916 no conserved hypothetical protein 277 3NTIU Polyketide cyclase / dehydrase and lipid transport I METABOLISM Lipid transport and metabolism ACIAD2350 CDS -1 2312018 2312542 no putative deaminase 348 3NN6N Catalyzes the deamination of adenosine to inosine at the wobble position 34 of tRNA(Arg2) F METABOLISM Nucleotide transport and metabolism ACIAD2350 CDS -1 2312018 2312542 no putative deaminase 348 3NN6N Catalyzes the deamination of adenosine to inosine at the wobble position 34 of tRNA(Arg2) J INFORMATION STORAGE AND PROCESSING Translation, ribosomal structure and biogenesis ACIAD2351 CDS -2 2312548 2313669 no putative enoyl-CoA hydratase/isomerase 773 3NK03 Enoyl-CoA hydratase I METABOLISM Lipid transport and metabolism ACIAD2352 CDS -3 2313666 2314379 no ung uracil-DNA glycosylase 484 3NITV Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine L INFORMATION STORAGE AND PROCESSING Replication, recombination and repair ACIAD2353 CDS -1 2314433 2315029 no putative 6-pyruvoyl-tetrahydropterin synthase 402 3NIPN 6-pyruvoyl tetrahydropterin synthase H METABOLISM Coenzyme transport and metabolism ACIAD2354 CDS -2 2315188 2316156 no xcpX general secretion pathway protein K 626 3NJ8R Type II secretion system (T2SS), protein K U CELLULAR PROCESSES AND SIGNALING Intracellular trafficking, secretion, and vesicular transport ACIAD2355 CDS -3 2316171 2316797 no xcpW general secretion pathway protein J precursor (PilD-dependent protein pddD) 405 3NKPG general secretion pathway protein U CELLULAR PROCESSES AND SIGNALING Intracellular trafficking, secretion, and vesicular transport ACIAD2356 CDS -1 2316794 2317180 no xcpV general secretion pathway protein I precursor (PilD-dependent protein pddC) 236 3NNHX Type II secretion system (T2SS), protein I N CELLULAR PROCESSES AND SIGNALING Cell motility ACIAD2356 CDS -1 2316794 2317180 no xcpV general secretion pathway protein I precursor (PilD-dependent protein pddC) 236 3NNHX Type II secretion system (T2SS), protein I U CELLULAR PROCESSES AND SIGNALING Intracellular trafficking, secretion, and vesicular transport ACIAD2357 CDS -3 2317170 2317718 no putative general secretion pathway protein G precursor 360 3NTKM Prokaryotic N-terminal methylation motif S POORLY CHARACTERIZED Function unknown ACIAD2358 CDS -3 2317731 2318345 no putative transcriptional regulator 397 3NJ73 Transcriptional regulator K INFORMATION STORAGE AND PROCESSING Transcription ACIAD2359 CDS -3 2318379 2319152 no conserved hypothetical protein; putative deoxyribonuclease 514 3NJ9T TatD related DNase L INFORMATION STORAGE AND PROCESSING Replication, recombination and repair ACIAD2360 CDS -1 2319170 2319514 no pilZ type 4 fimbrial biogenesis protein 224 3NNKH PilZ domain N CELLULAR PROCESSES AND SIGNALING Cell motility ACIAD2360 CDS -1 2319170 2319514 no pilZ type 4 fimbrial biogenesis protein 224 3NNKH PilZ domain U CELLULAR PROCESSES AND SIGNALING Intracellular trafficking, secretion, and vesicular transport ACIAD2361 CDS -2 2319517 2320512 no holB DNA polymerase III, delta prime subunit 676 3NK7S DNA polymerase III L INFORMATION STORAGE AND PROCESSING Replication, recombination and repair ACIAD2362 CDS -2 2320519 2321280 no kdsB 3-deoxy-manno-octulosonate cytidylyltransferase 502 3NK83 Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria M CELLULAR PROCESSES AND SIGNALING Cell wall/membrane/envelope biogenesis ACIAD2363 CDS -2 2321290 2322300 no lpxK tetraacyldisaccharide 4'-kinase (Lipid A 4'-kinase) 685 3NJHV Transfers the gamma-phosphate of ATP to the 4'-position of a tetraacyldisaccharide 1-phosphate intermediate (termed DS-1- P) to form tetraacyldisaccharide 1,4'-bis-phosphate (lipid IVA) M CELLULAR PROCESSES AND SIGNALING Cell wall/membrane/envelope biogenesis ACIAD2365 CDS -2 2322307 2324031 no msbA lipid transport protein, flippase (ABC superfamily, membrane (N-terminal), atp_bind (C-terminal)) 1080 3NIG0 Involved in lipid A export and possibly also in glycerophospholipid export and for biogenesis of the outer membrane. Transmembrane domains (TMD) form a pore in the inner membrane and the ATP-binding domain (NBD) is responsible for energy generation V CELLULAR PROCESSES AND SIGNALING Defense mechanisms ACIAD2366 CDS -2 2324356 2325246 no spoOJ chromosome partitioning protein 567 3NJZB Belongs to the ParB family K INFORMATION STORAGE AND PROCESSING Transcription ACIAD2367 CDS -3 2325243 2326025 no soj chromosome partitioning protein 492 3NIYN 4Fe-4S iron sulfur cluster binding proteins, NifH/frxC family D CELLULAR PROCESSES AND SIGNALING Cell cycle control, cell division, chromosome partitioning ACIAD2368 CDS -2 2326039 2326677 no gidB glucose-inhibited division protein B (methyltransferase) 410 3NJAY Specifically methylates the N7 position of guanine in position 527 of 16S rRNA J INFORMATION STORAGE AND PROCESSING Translation, ribosomal structure and biogenesis ACIAD2369 CDS -2 2326762 2327451 no putative nucleotidyl transferase 457 3NJ0U COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits (eIF-2Bgamma eIF-2Bepsilon) J INFORMATION STORAGE AND PROCESSING Translation, ribosomal structure and biogenesis ACIAD2369 CDS -2 2326762 2327451 no putative nucleotidyl transferase 457 3NJ0U COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits (eIF-2Bgamma eIF-2Bepsilon) M CELLULAR PROCESSES AND SIGNALING Cell wall/membrane/envelope biogenesis ACIAD2370 CDS -3 2327448 2328470 no conserved hypothetical protein; putative phosphotransferase related to Ser/Thr protein kinase 690 3NJZE Phosphotransferase enzyme family S POORLY CHARACTERIZED Function unknown ACIAD2371 CDS +3 2328576 2331035 no ostA organic solvent tolerance protein precursor or increased membrane permeability protein 1649 3NJSZ Together with LptE, is involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane M CELLULAR PROCESSES AND SIGNALING Cell wall/membrane/envelope biogenesis ACIAD2372 CDS +2 2331020 2332375 no surA peptidyl-prolyl cis-trans isomerase 844 3NIEI Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation M CELLULAR PROCESSES AND SIGNALING Cell wall/membrane/envelope biogenesis ACIAD2373 CDS -1 2332553 2333077 no hfq host factor I for bacteriophage Q beta replication, a growth-related protein 185 3NK0S RNA chaperone that binds small regulatory RNA (sRNAs) and mRNAs to facilitate mRNA translational regulation in response to envelope stress, environmental stress and changes in metabolite concentrations. Also binds with high specificity to tRNAs J INFORMATION STORAGE AND PROCESSING Translation, ribosomal structure and biogenesis ACIAD2374 CDS -1 2333168 2334112 no miaA delta(2)-isopentenylpyrophosphate tRNA-adenosine transferase 619 3NJ8H Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A) F METABOLISM Nucleotide transport and metabolism ACIAD2375 CDS -1 2334119 2336080 no mutL enzyme in methyl-directed mismatch repair, stimulates binding of Vsr and MutS to heteroduplex DNA 1275 3NIU8 This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex L INFORMATION STORAGE AND PROCESSING Replication, recombination and repair ACIAD2376 CDS -3 2336082 2336558 no putative ATPase with strong ADP affinity 317 3NM6D Threonylcarbamoyl adenosine biosynthesis protein TsaE S POORLY CHARACTERIZED Function unknown ACIAD2377 CDS +2 2336684 2337598 no putative pseudouridylate synthase 630 3NK7C RNA pseudouridylate synthase J INFORMATION STORAGE AND PROCESSING Translation, ribosomal structure and biogenesis ACIAD2378 CDS +3 2337708 2338037 no conserved hypothetical protein 206 3NNVR RelB antitoxin L INFORMATION STORAGE AND PROCESSING Replication, recombination and repair ACIAD2379 CDS +3 2338119 2338574 no putative acetyltransferase 298 3NN6T Acetyltransferase (GNAT) domain K INFORMATION STORAGE AND PROCESSING Transcription ACIAD2380 CDS -2 2338567 2339286 no rsuA 16S rRNA pseudouridylate 516 synthase 481 3NJ1F Belongs to the pseudouridine synthase RsuA family J INFORMATION STORAGE AND PROCESSING Translation, ribosomal structure and biogenesis ACIAD2383 CDS +1 2339965 2340420 no putative membrane protein 280 3NN43 Protein of unknown function (DUF441) S POORLY CHARACTERIZED Function unknown ACIAD2384 CDS -2 2340640 2341560 no metR transcriptional regulator 612 3NJ6C Transcriptional regulator K INFORMATION STORAGE AND PROCESSING Transcription ACIAD2385 CDS +3 2342094 2343305 no putative permease (MFS superfamily) 754 3NKNC Sugar (and other) transporter E METABOLISM Amino acid transport and metabolism ACIAD2385 CDS +3 2342094 2343305 no putative permease (MFS superfamily) 754 3NKNC Sugar (and other) transporter G METABOLISM Carbohydrate transport and metabolism ACIAD2385 CDS +3 2342094 2343305 no putative permease (MFS superfamily) 754 3NKNC Sugar (and other) transporter P METABOLISM Inorganic ion transport and metabolism ACIAD2386 CDS -1 2343374 2344321 no rih ribonucleoside hydrolase 637 3NKZX Inosine-uridine preferring nucleoside hydrolase G METABOLISM Carbohydrate transport and metabolism ACIAD2388 CDS -2 2344399 2345250 no putative oxidoreductase 577 3NR1D non-haem dioxygenase in morphine synthesis N-terminal C METABOLISM Energy production and conversion ACIAD2389 CDS -1 2345375 2346625 no putative transport protein; putative NUP family transport protein 773 3NKSE Na+ dependent nucleoside transporter C-terminus U CELLULAR PROCESSES AND SIGNALING Intracellular trafficking, secretion, and vesicular transport ACIAD2390 CDS -1 2347217 2348062 no putative potassium channel protein 505 3NJGB Ion transport protein T CELLULAR PROCESSES AND SIGNALING Signal transduction mechanisms ACIAD2391 CDS -1 2348336 2348701 no conserved hypothetical protein 243 3NNJY S POORLY CHARACTERIZED Function unknown ACIAD2392 CDS +1 2348944 2349882 no rbsK ribokinase 593 3NJ95 Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway H METABOLISM Coenzyme transport and metabolism ACIAD2393 CDS -1 2350022 2350354 no cpiR transcriptional repressor of CpiA 223 3NP6Y Helix-turn-helix XRE-family like proteins K INFORMATION STORAGE AND PROCESSING Transcription ACIAD2395 CDS -2 2350951 2353590 no acnB aconitate hydratase 2 1733 3NM2Z Belongs to the aconitase IPM isomerase family C METABOLISM Energy production and conversion ACIAD2397 CDS -1 2354618 2355031 no conserved hypothetical protein 279 3NNVW S POORLY CHARACTERIZED Function unknown ACIAD2398 CDS -1 2355083 2355436 no csoR Copper-sensing transcriptional repressor 231 3NRTJ Metal-sensitive transcriptional repressor S POORLY CHARACTERIZED Function unknown ACIAD2400 CDS +1 2355733 2358141 no copA Copper-exporting P-type ATPase A 1518 3NIYQ P-type ATPase P METABOLISM Inorganic ion transport and metabolism ACIAD2401 CDS +3 2358141 2358353 no copZ copper insertion chaperone and transporter component 137 3NSGJ Heavy-metal-associated domain C METABOLISM Energy production and conversion ACIAD2402 CDS -2 2358433 2362932 no conserved hypothetical protein 2935 3NII7 TamB, inner membrane protein subunit of TAM complex M CELLULAR PROCESSES AND SIGNALING Cell wall/membrane/envelope biogenesis ACIAD2403 CDS -2 2362957 2365650 no conserved hypothetical protein; putative outer membrane protein 1743 3NIV8 Surface antigen M CELLULAR PROCESSES AND SIGNALING Cell wall/membrane/envelope biogenesis ACIAD2404 CDS +3 2365866 2367140 no putative permease (MFS superfamily) 803 3NIXV Transmembrane secretion effector E METABOLISM Amino acid transport and metabolism ACIAD2404 CDS +3 2365866 2367140 no putative permease (MFS superfamily) 803 3NIXV Transmembrane secretion effector G METABOLISM Carbohydrate transport and metabolism ACIAD2404 CDS +3 2365866 2367140 no putative permease (MFS superfamily) 803 3NIXV Transmembrane secretion effector P METABOLISM Inorganic ion transport and metabolism ACIAD2405 CDS +1 2367145 2367780 no putative ubiquinone biosynthesis protein 413 3NK47 Oxygenase that introduces the hydroxyl group at carbon five of 2-nonaprenyl-3-methyl-6-methoxy-1,4-benzoquinol resulting in the formation of 2-nonaprenyl-3-methyl-5-hydroxy-6-methoxy-1,4- benzoquinol H METABOLISM Coenzyme transport and metabolism ACIAD2406 CDS -2 2367826 2368320 no conserved hypothetical protein; putative signal peptide 338 3NMBA Protein of unknown function (DUF2799) S POORLY CHARACTERIZED Function unknown ACIAD2407 CDS -1 2368619 2369011 no putative 2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase 268 3NNNF 7,8-dihydro-6-hydroxymethylpterin-pyrophosphokinase (HPPK) H METABOLISM Coenzyme transport and metabolism ACIAD2408 CDS -3 2369037 2369417 no folB dihydroneopterin aldolase 248 3NNI7 Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin H METABOLISM Coenzyme transport and metabolism ACIAD2409 CDS -3 2369436 2370743 no conserved hypothetical protein; putative kinase 850 3NJ0D ABC1 family S POORLY CHARACTERIZED Function unknown ACIAD2411 CDS -1 2370755 2371567 no molybdopterin biosynthesis protein (moeB) OR thiamin-thiazole moiety synthesis (thiF) 537 3NIJ0 COG0476 Dinucleotide-utilizing enzymes involved in molybdopterin and thiamine biosynthesis family 2 H METABOLISM Coenzyme transport and metabolism ACIAD2412 CDS +2 2373209 2375191 no conserved hypothetical protein; putative chaperone 1269 3NMYB DnaJ molecular chaperone homology domain O CELLULAR PROCESSES AND SIGNALING Posttranslational modification, protein turnover, chaperones ACIAD2413 CDS -3 2375301 2377001 no hscC chaperone protein 1097 3NMIB Hsp70 protein O CELLULAR PROCESSES AND SIGNALING Posttranslational modification, protein turnover, chaperones ACIAD2415 CDS +1 2377135 2379747 no conserved hypothetical protein; putative membrane protein 1687 3NT3Y Uncharacterised conserved protein (DUF2156) S POORLY CHARACTERIZED Function unknown ACIAD2416 CDS -1 2380001 2380771 no putative oxidoreductase, short-chain dehydrogenase/reductase family 488 3NKSB Belongs to the short-chain dehydrogenases reductases (SDR) family I METABOLISM Lipid transport and metabolism ACIAD2416 CDS -1 2380001 2380771 no putative oxidoreductase, short-chain dehydrogenase/reductase family 488 3NKSB Belongs to the short-chain dehydrogenases reductases (SDR) family Q METABOLISM Secondary metabolites biosynthesis, transport and catabolism ACIAD2417 CDS -1 2381237 2382061 no hemK methyl transferase 558 3NKB7 Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif J INFORMATION STORAGE AND PROCESSING Translation, ribosomal structure and biogenesis ACIAD2418 CDS -2 2382061 2383191 no prfA peptide chain release factor 1 733 3NJCS Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA J INFORMATION STORAGE AND PROCESSING Translation, ribosomal structure and biogenesis ACIAD2419 CDS +2 2383607 2384068 no conserved hypothetical protein; putative signal peptide 154 3NM50 S POORLY CHARACTERIZED Function unknown ACIAD2420 CDS +1 2384206 2385228 no putative monooxygenase 677 3NKWP Luciferase-like monooxygenase C METABOLISM Energy production and conversion ACIAD2421 CDS -2 2385310 2386755 no putative diguanylate cyclase/phosphodiesterase 945 3NJYB Putative diguanylate phosphodiesterase T CELLULAR PROCESSES AND SIGNALING Signal transduction mechanisms ACIAD2422 CDS -2 2386960 2387796 no conserved hypothetical protein 544 3NIIN Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the phosphoenolpyruvate synthase (PEPS) by catalyzing its phosphorylation dephosphorylation H METABOLISM Coenzyme transport and metabolism ACIAD2423 CDS +2 2387954 2390332 no ppsA phosphoenolpyruvate synthase 1542 3NJC4 Catalyzes the phosphorylation of pyruvate to phosphoenolpyruvate G METABOLISM Carbohydrate transport and metabolism ACIAD2424 CDS +1 2390401 2391162 no conserved hypothetical protein; putative membrane protein 472 3NK23 Domain of unknown function (DUF4339) S POORLY CHARACTERIZED Function unknown ACIAD2425 CDS +1 2391463 2392524 no cyoA cytochrome o ubiquinol oxidase subunit II 702 3NK4D COX Aromatic Rich Motif C METABOLISM Energy production and conversion ACIAD2426 CDS +1 2392528 2394516 no cyoB cytochrome o ubiquinol oxidase subunit I 1327 3NJ4I Belongs to the heme-copper respiratory oxidase family C METABOLISM Energy production and conversion ACIAD2427 CDS +2 2394521 2395141 no cyoC cytochrome o ubiquinol oxidase subunit III 415 3NIPT Cytochrome c oxidase subunit III C METABOLISM Energy production and conversion ACIAD2428 CDS +1 2395141 2395467 no cyoD cytochrome o ubiquinol oxidase subunit IV 207 3NNHS Prokaryotic Cytochrome C oxidase subunit IV C METABOLISM Energy production and conversion ACIAD2429 CDS +2 2395469 2396356 no cyoE protoheme IX farnesyltransferase (heme O biosynthesis) 573 3NK0G Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group O CELLULAR PROCESSES AND SIGNALING Posttranslational modification, protein turnover, chaperones ACIAD2430 CDS +2 2396534 2396920 no rpsF 30S ribosomal protein S6 244 3NN4A Binds together with S18 to 16S ribosomal RNA J INFORMATION STORAGE AND PROCESSING Translation, ribosomal structure and biogenesis ACIAD2431 CDS +1 2396932 2397159 no rpsR 30S ribosomal protein S18 151 3NPB6 Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit J INFORMATION STORAGE AND PROCESSING Translation, ribosomal structure and biogenesis ACIAD2432 CDS +3 2397168 2397614 no rplI 50S ribosomal protein L9 271 3NKTG Binds to the 23S rRNA J INFORMATION STORAGE AND PROCESSING Translation, ribosomal structure and biogenesis ACIAD2433 CDS +3 2397789 2399234 no dnaB replicative DNA helicase;chromosome replication, chain elongation 934 3NK54 it exhibits DNA-dependent ATPase activity and contains distinct active sites for ATP binding, DNA binding, and interaction with DnaC protein, primase, and other prepriming proteins L INFORMATION STORAGE AND PROCESSING Replication, recombination and repair ACIAD2434 CDS +3 2399265 2400341 no alr alanine racemase 1, biosynthetic 724 3NJ0G Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids E METABOLISM Amino acid transport and metabolism ACIAD2435 CDS -2 2400424 2401158 no conserved hypothetical protein; putative proteasome protease 492 3NKMP Proteasome subunit O CELLULAR PROCESSES AND SIGNALING Posttranslational modification, protein turnover, chaperones ACIAD2436 CDS -2 2401174 2401953 no conserved hypothetical protein; putative transglutaminase 531 3NJC3 Bacterial transglutaminase-like N-terminal region E METABOLISM Amino acid transport and metabolism ACIAD2437 CDS -3 2401950 2402498 no conserved hypothetical protein 365 3NM2Q A predicted alpha-helical domain with a conserved ER motif. S POORLY CHARACTERIZED Function unknown ACIAD2438 CDS -2 2402581 2404131 no conserved hypothetical protein 1032 3NKVG Circularly permuted ATP-grasp type 2 S POORLY CHARACTERIZED Function unknown ACIAD2439 CDS +3 2404338 2405345 no mdcH transcriptional factor 674 3NIP3 WYL domain K INFORMATION STORAGE AND PROCESSING Transcription ACIAD2440 CDS -1 2405708 2407588 no mnmG tRNA uridine 5-carboxymethylaminomethyl modification enzyme mnmG 1243 3NKEB NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34 D CELLULAR PROCESSES AND SIGNALING Cell cycle control, cell division, chromosome partitioning ACIAD2441 CDS +3 2407767 2408057 no conserved hypothetical protein; putative signal peptide 194 3NQ55 S POORLY CHARACTERIZED Function unknown ACIAD2443 CDS +1 2408200 2409111 no prmA methylation of 50S ribosomal subunit protein L11 (ribosomal protein L11 methyltransferase) 612 3NIXE Methylates ribosomal protein L11 J INFORMATION STORAGE AND PROCESSING Translation, ribosomal structure and biogenesis ACIAD2444 CDS +3 2409129 2409677 no conserved hypothetical protein 368 3NK1F Protein of unknown function (DUF3426) S POORLY CHARACTERIZED Function unknown ACIAD2446 CDS +3 2410329 2410619 no fis DNA-binding protein for site-specific recombination, transcription of rRNA and tRNA operons and DNA replication 185 3NNW8 Activates ribosomal RNA transcription. Plays a direct role in upstream activation of rRNA promoters K INFORMATION STORAGE AND PROCESSING Transcription ACIAD2446 CDS +3 2410329 2410619 no fis DNA-binding protein for site-specific recombination, transcription of rRNA and tRNA operons and DNA replication 185 3NNW8 Activates ribosomal RNA transcription. Plays a direct role in upstream activation of rRNA promoters L INFORMATION STORAGE AND PROCESSING Replication, recombination and repair ACIAD2447 CDS +3 2410701 2412275 no purH bifunctional protein [Includes: phosphoribosylaminoimidazolecarboxamide formyltransferase (AICAR transformylase); IMP cyclohydrolase (Inosinicase) (IMP synthetase) (ATIC)] 1013 3NJ4P Bifunctional purine biosynthesis protein PurH F METABOLISM Nucleotide transport and metabolism ACIAD2448 CDS +3 2412387 2413694 no purD phosphoribosylamine--glycine ligase (GARS) (Glycinamide ribonucleotide synthetase) (Phosphoribosylglycinamide synthetase) 865 3NJ3Q Belongs to the GARS family F METABOLISM Nucleotide transport and metabolism ACIAD2449 CDS +1 2413978 2414847 no putative lipoprotein, attached to the cytoplasmic membrane 555 3NT1H NLPA lipoprotein P METABOLISM Inorganic ion transport and metabolism ACIAD2450 CDS +2 2414921 2415946 no D- and L-methionine transport protein (ABC superfamily, atp_bind) (metN-like) 662 3NK3K Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system P METABOLISM Inorganic ion transport and metabolism ACIAD2451 CDS +1 2415943 2416638 no putative permease protein (ABC superfamily, membrane) 432 3NIU7 Binding-protein-dependent transport system inner membrane component P METABOLISM Inorganic ion transport and metabolism ACIAD2452 CDS +2 2416769 2417503 no putative hydroxyacylglutathione hydrolase (GloB) 499 3NJQS Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid S POORLY CHARACTERIZED Function unknown ACIAD2453 CDS +1 2417824 2418027 no conserved hypothetical protein 134 3NPAV S POORLY CHARACTERIZED Function unknown ACIAD2455 CDS -1 2418446 2419327 no ubiA 4-hydroxybenzoate octaprenyltransferase (4-HB polyprenyltransferase) 595 3NIYC Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate H METABOLISM Coenzyme transport and metabolism ACIAD2456 CDS -2 2419336 2419839 no ubiC chorismate pyruvate lyase 346 3NKMX Removes the pyruvyl group from chorismate, with concomitant aromatization of the ring, to provide 4- hydroxybenzoate (4HB) for the ubiquinone pathway H METABOLISM Coenzyme transport and metabolism ACIAD2457 CDS +1 2420011 2420223 no hypothetical protein; putative membrane protein 148 3NS5U S POORLY CHARACTERIZED Function unknown ACIAD2458 CDS -3 2420313 2421728 no glnA glutamine synthetase 957 3NJCF glutamine synthetase E METABOLISM Amino acid transport and metabolism ACIAD2460 CDS +1 2422351 2422860 no hypothetical protein; putative signal peptide 339 3NMT7 S POORLY CHARACTERIZED Function unknown ACIAD2461 CDS +2 2423066 2423650 no trpG bifunctional protein:[Includes: para-aminobenzoate synthase glutamine amidotransferase component II (ADC synthase); anthranilate synthase component II] 403 3NIZ1 component II E METABOLISM Amino acid transport and metabolism ACIAD2461 CDS +2 2423066 2423650 no trpG bifunctional protein:[Includes: para-aminobenzoate synthase glutamine amidotransferase component II (ADC synthase); anthranilate synthase component II] 403 3NIZ1 component II H METABOLISM Coenzyme transport and metabolism ACIAD2462 CDS +2 2423651 2424700 no trpD anthranilate phosphoribosyltransferase 663 3NIQH Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA) E METABOLISM Amino acid transport and metabolism ACIAD2463 CDS +3 2424660 2425517 no trpC indole-3-glycerol phosphate synthase (IGPS) 549 3NJGD Belongs to the TrpC family E METABOLISM Amino acid transport and metabolism ACIAD2464 CDS -2 2425555 2426040 no hypothetical protein 315 3NNCD S POORLY CHARACTERIZED Function unknown ACIAD2465 CDS +2 2426144 2426806 no conserved hypothetical protein 419 3NISV Smr domain S POORLY CHARACTERIZED Function unknown ACIAD2466 CDS -3 2426817 2427818 no xdhC xanthine dehydrogenase accessory factor 679 3NK3A XdhC and CoxI family O CELLULAR PROCESSES AND SIGNALING Posttranslational modification, protein turnover, chaperones ACIAD2467 CDS -1 2427833 2430214 no xdhB xanthine dehydrogenase, large subunit 1587 3NKF4 Aldehyde oxidase and xanthine dehydrogenase, a/b hammerhead domain F METABOLISM Nucleotide transport and metabolism ACIAD2468 CDS -3 2430216 2431712 no xdhA xanthine dehydrogenase, small subunit 971 3NMU6 CO dehydrogenase flavoprotein C-terminal domain F METABOLISM Nucleotide transport and metabolism ACIAD2470 CDS +2 2432069 2432662 no folE GTP cyclohydrolase I 386 3NKQ6 GTP cyclohydrolase H METABOLISM Coenzyme transport and metabolism ACIAD2471 CDS +3 2432766 2433317 no putative DedA family protein 349 3NMBI SNARE associated Golgi protein S POORLY CHARACTERIZED Function unknown ACIAD2472 CDS +2 2433503 2434714 no putative transport protein (MFS superfamily) 750 1RPQJ MFS-type transporter U CELLULAR PROCESSES AND SIGNALING Intracellular trafficking, secretion, and vesicular transport ACIAD2473 CDS -1 2434742 2435548 no conserved hypothetical protein; putative membrane protein 531 3NKNZ Protein of unknown function (DUF817) S POORLY CHARACTERIZED Function unknown ACIAD2474 CDS -3 2435553 2436629 no hemE uroporphyrinogen decarboxylase 719 3NIKI Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III H METABOLISM Coenzyme transport and metabolism ACIAD2475 CDS +3 2436822 2438210 no conserved hypothetical protein; putative signal peptide 849 3NJY7 ErfK YbiS YcfS YnhG family protein M CELLULAR PROCESSES AND SIGNALING Cell wall/membrane/envelope biogenesis ACIAD2476 CDS +3 2438442 2439131 no conserved hypothetical protein 486 3NJ1E Belongs to the pirin family S POORLY CHARACTERIZED Function unknown ACIAD2477 CDS -3 2439177 2442413 no putative CRISPR-associated helicase Cas3 2148 3NKDP CRISPR-associated helicase, Cas3 L INFORMATION STORAGE AND PROCESSING Replication, recombination and repair ACIAD2479 CDS +2 2442800 2443189 no hypothetical protein 50.1 1S2IZ Phage antirepressor protein KilAC domain K INFORMATION STORAGE AND PROCESSING Transcription ACIAD2480 CDS +1 2443261 2444466 no putative CRISPR-associated protein 777 3NKG2 S POORLY CHARACTERIZED Function unknown ACIAD2481 CDS +3 2444463 2445347 no putative CRISPR-associated protein csy2 583 3NT20 CRISPR-associated protein (Cas_Csy2) S POORLY CHARACTERIZED Function unknown ACIAD2482 CDS +2 2445377 2446438 no putative CRISPR-associated protein Csy3 707 3NKBF CRISPR-associated protein (Cas_Csy3) S POORLY CHARACTERIZED Function unknown ACIAD2483 CDS +1 2446441 2447052 no putative CRISPR-associated endoribonuclease Cas6/Csy4 404 3NMJ8 CRISPR-associated protein (Cas_Csy4) S POORLY CHARACTERIZED Function unknown ACIAD2484 CDS +3 2447064 2448017 no putative CRISPR-associated protein Cas1 624 3NKQR CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain spacers, sequences complementary to antecedent mobile elements, and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Acts as a dsDNA endonuclease. Involved in the integration of spacer DNA into the CRISPR cassette L INFORMATION STORAGE AND PROCESSING Replication, recombination and repair ACIAD2500 CDS -3 2453622 2454584 no putative two-component response regulator protein 629 3NM17 helix_turn_helix, Lux Regulon T CELLULAR PROCESSES AND SIGNALING Signal transduction mechanisms ACIAD2501 CDS -1 2454581 2458045 no putative two-component sensor kinase 2198 3NTJS His Kinase A (phosphoacceptor) domain T CELLULAR PROCESSES AND SIGNALING Signal transduction mechanisms ACIAD2502 CDS +3 2458236 2459858 no conserved hypothetical protein; putative membrane protein 1051 3NKRZ Belongs to the purine-cytosine permease (2.A.39) family F METABOLISM Nucleotide transport and metabolism ACIAD2503 CDS +2 2460086 2460157 no pqqA coenzyme PQQ synthesis protein A (Coenzyme PQQ synthesis protein IV) 41.6 1Z3N7 Required for coenzyme pyrroloquinoline quinone (PQQ) biosynthesis. PQQ is probably formed by cross-linking a specific glutamate to a specific tyrosine residue and excising these residues from the peptide S POORLY CHARACTERIZED Function unknown ACIAD2504 CDS +3 2460231 2461145 no pqqB coenzyme PQQ synthesis protein B (Coenzyme PQQ synthesis protein V) 627 3NKHW May be involved in the transport of PQQ or its precursor to the periplasm S POORLY CHARACTERIZED Function unknown ACIAD2505 CDS +1 2461135 2461902 no pqqC coenzyme PQQ synthesis protein C (Coenzyme PQQ synthesis protein I) 540 3NMAD Ring cyclization and eight-electron oxidation of 3a-(2- amino-2-carboxyethyl)-4,5-dioxo-4,5,6,7,8,9-hexahydroquinoline- 7,9-dicarboxylic-acid to PQQ H METABOLISM Coenzyme transport and metabolism ACIAD2506 CDS +3 2461875 2462174 no pqqD coenzyme PQQ synthesis protein D (Coenzyme PQQ synthesis protein II) 198 3NNYJ Coenzyme PQQ synthesis protein D (PqqD) S POORLY CHARACTERIZED Function unknown ACIAD2507 CDS +2 2462156 2463331 no pqqE coenzyme PQQ synthesis protein E (Coenzyme PQQ synthesis protein III) 794 3NSYT Iron-sulfur cluster-binding domain H METABOLISM Coenzyme transport and metabolism ACIAD2508 CDS +1 2463328 2464374 no acdP Zn-dependent dipeptidase 721 3NKC9 Membrane dipeptidase (Peptidase family M19) E METABOLISM Amino acid transport and metabolism ACIAD2509 CDS -3 2464428 2465213 no bdhA 3-hydroxybutyrate dehydrogenase 497 3NK65 KR domain I METABOLISM Lipid transport and metabolism ACIAD2509 CDS -3 2464428 2465213 no bdhA 3-hydroxybutyrate dehydrogenase 497 3NK65 KR domain Q METABOLISM Secondary metabolites biosynthesis, transport and catabolism ACIAD2510 CDS -1 2465288 2466706 no putative D-beta-hydroxybutyrate permease 885 3NISZ COG2610 H gluconate symporter and related permeases E METABOLISM Amino acid transport and metabolism ACIAD2510 CDS -1 2465288 2466706 no putative D-beta-hydroxybutyrate permease 885 3NISZ COG2610 H gluconate symporter and related permeases G METABOLISM Carbohydrate transport and metabolism ACIAD2511 CDS +1 2467153 2468073 no putative transcriptional regulator (LysR family) 595 3NKSM LysR substrate binding domain K INFORMATION STORAGE AND PROCESSING Transcription ACIAD2513 CDS +2 2468252 2468956 no atoD acetoacetyl-CoA transferase, alpha subunit 459 3NKXY Coenzyme A transferase I METABOLISM Lipid transport and metabolism ACIAD2514 CDS +1 2468959 2469603 no atoA acetoacetyl-CoA transferase, beta subunit 413 3NIWE Coenzyme A transferase I METABOLISM Lipid transport and metabolism ACIAD2515 CDS +3 2469711 2471120 no atoE short-chain fatty acid transporter (scFAT family) 887 3NISP Short chain fatty acid transporter I METABOLISM Lipid transport and metabolism ACIAD2516 CDS +2 2471171 2472355 no atoB acetyl-CoA acetyltransferase with thiolase domain 752 3NIM7 Thiolase, C-terminal domain I METABOLISM Lipid transport and metabolism ACIAD2517 CDS -3 2472480 2474210 no bccA Acetyl-/propionyl-coenzyme A carboxylase alpha chain [Includes: Biotin carboxylase ; Biotin carboxyl carrier protein (BCCP)] 1125 3NM3W Biotin carboxylase, N-terminal domain I METABOLISM Lipid transport and metabolism ACIAD2518 CDS -1 2474207 2475805 no pxpC putative L-5-oxoprolinase (ATP-dependent) subunit C 1061 3NJIA Allophanate hydrolase subunit 2 E METABOLISM Amino acid transport and metabolism ACIAD2519 CDS -1 2475824 2476636 no pxpI putative D-5-oxoproline epimerase 557 3NK64 Belongs to the D-glutamate cyclase family S POORLY CHARACTERIZED Function unknown ACIAD2520 CDS -1 2476637 2477401 no pxpA putative oxoprolinase subunit A 499 3NJZ6 Belongs to the UPF0271 (lamB) family S POORLY CHARACTERIZED Function unknown ACIAD2521 CDS -1 2477414 2478640 no pxpG putative 5-oxoproline transporter 769 3NJS1 Natural resistance-associated macrophage protein P METABOLISM Inorganic ion transport and metabolism ACIAD2522 CDS -2 2479003 2479932 no putative transcriptional regulator 602 3NMDI LysR substrate binding domain K INFORMATION STORAGE AND PROCESSING Transcription ACIAD2523 CDS +1 2480209 2481210 no putative transcriptional regulator (GntR family) 649 1RZ64 Transcriptional regulator GntR family K INFORMATION STORAGE AND PROCESSING Transcription ACIAD2524 CDS -2 2481226 2482407 no putative substrate binding protein (ABC superfamily, peri_bind) 817 3NR46 Bacterial extracellular solute-binding protein E METABOLISM Amino acid transport and metabolism ACIAD2525 CDS -2 2482834 2484168 no mgsC putative N-methyl glutamate synthase subunit C 873 3NJEJ Belongs to the glutamate synthase family E METABOLISM Amino acid transport and metabolism ACIAD2526 CDS -2 2484196 2484924 no mgsB putative N-methyl glutamate synthase subunit B 347 3NKXD GXGXG motif C METABOLISM Energy production and conversion ACIAD2527 CDS -2 2484955 2485878 no mgsA putative N-methyl glutamate synthase subunit A 615 3NM13 Glutamine amidotransferase domain F METABOLISM Nucleotide transport and metabolism ACIAD2528 CDS -3 2485926 2487317 no gmaS putative gamma glutamylmethylamide synthetase 945 3NMPF Glutamine synthetase, catalytic domain E METABOLISM Amino acid transport and metabolism ACIAD2530 CDS +3 2487606 2488202 no putative transcriptional regulator (methylamine catabolism) 394 3NKAG Cro/C1-type HTH DNA-binding domain K INFORMATION STORAGE AND PROCESSING Transcription ACIAD2531 CDS -2 2488300 2489451 no putative sugar efflux transporter (MFS superfamily) 691 3NKD6 Major Facilitator Superfamily E METABOLISM Amino acid transport and metabolism ACIAD2531 CDS -2 2488300 2489451 no putative sugar efflux transporter (MFS superfamily) 691 3NKD6 Major Facilitator Superfamily G METABOLISM Carbohydrate transport and metabolism ACIAD2531 CDS -2 2488300 2489451 no putative sugar efflux transporter (MFS superfamily) 691 3NKD6 Major Facilitator Superfamily P METABOLISM Inorganic ion transport and metabolism ACIAD2533 CDS +3 2489550 2490416 no putative transcriptional regulator (LysR family) 570 3NT54 LysR substrate binding domain K INFORMATION STORAGE AND PROCESSING Transcription ACIAD2534 CDS +1 2490601 2491911 no putative ammonium transporter 846 3NJRA Ammonium Transporter Family P METABOLISM Inorganic ion transport and metabolism ACIAD2535 CDS -2 2492005 2493486 no putative transporter (MFS superfamily) 944 3NIH1 Sugar (and other) transporter E METABOLISM Amino acid transport and metabolism ACIAD2535 CDS -2 2492005 2493486 no putative transporter (MFS superfamily) 944 3NIH1 Sugar (and other) transporter G METABOLISM Carbohydrate transport and metabolism ACIAD2535 CDS -2 2492005 2493486 no putative transporter (MFS superfamily) 944 3NIH1 Sugar (and other) transporter P METABOLISM Inorganic ion transport and metabolism ACIAD2536 CDS -2 2493631 2494989 no putative coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductase 930 3NKKD Luciferase-like monooxygenase C METABOLISM Energy production and conversion ACIAD2537 CDS -2 2495185 2496498 no putative acyl-CoA dehydrogenase 867 3NM80 Acyl-CoA dehydrogenase, C-terminal domain I METABOLISM Lipid transport and metabolism ACIAD2538 CDS -2 2496859 2497248 no putative gamma-carboxymuconolactone decarboxylase 260 3NT9J Carboxymuconolactone decarboxylase family S POORLY CHARACTERIZED Function unknown ACIAD2539 CDS -3 2497245 2498696 no tgnE succinate-semialdehyde dehydrogenase 952 3NIN2 Involved in the biosynthesis of the osmoprotectant glycine betaine. Catalyzes the reversible oxidation of betaine aldehyde to the corresponding acid C METABOLISM Energy production and conversion ACIAD2540 CDS -1 2498849 2500015 no conserved hypothetical protein; putative signal peptide 795 3NM0Q hemolysin activation secretion protein U CELLULAR PROCESSES AND SIGNALING Intracellular trafficking, secretion, and vesicular transport ACIAD2541 CDS -2 2500039 2501442 no tgnP trigonelline permease 905 3NSPC Permease for cytosine/purines, uracil, thiamine, allantoin U CELLULAR PROCESSES AND SIGNALING Intracellular trafficking, secretion, and vesicular transport ACIAD2542 CDS -2 2501809 2503275 no tgnC MFMB ((Z)-2-((N-methylformamido)methylene)-5-hydroxy-butyrolactone) dehydrogenase 956 3NIN2 Involved in the biosynthesis of the osmoprotectant glycine betaine. Catalyzes the reversible oxidation of betaine aldehyde to the corresponding acid C METABOLISM Energy production and conversion ACIAD2543 CDS -1 2503250 2504332 no tgnB trigonelline monooxygenase, , oxygenase component 743 3NK6K Luciferase-like monooxygenase C METABOLISM Energy production and conversion ACIAD2544 CDS -2 2504335 2505267 no tgnA trigonelline oxygenase, reductase component 620 3NSY2 Flavin reductase like domain S POORLY CHARACTERIZED Function unknown ACIAD2545 CDS -3 2505297 2506088 no tgnD MFMS ((E)-2-((Nmethylformamido) methylene) succinate) hydrolase 535 3NJWU Serine aminopeptidase, S33 I METABOLISM Lipid transport and metabolism ACIAD2546 CDS -2 2506057 2506659 no tgnF SSA dehydrogenase stimulating protein 395 3NKQ7 Amino acid synthesis S POORLY CHARACTERIZED Function unknown ACIAD2547 CDS +2 2506793 2507485 no tgnR Trigonelline degradation transcriptional regulator 438 3NM6V FCD K INFORMATION STORAGE AND PROCESSING Transcription ACIAD2548 CDS +3 2507502 2507795 no conserved hypothetical protein 202 3NP3W Domain of unknown function (DUF1330) S POORLY CHARACTERIZED Function unknown ACIAD2549 CDS -1 2507921 2508592 no mgdD putative N-methyl glutamate dehydrogenase/oxidoreductase subunit D 448 3NN7E Sarcosine oxidase, gamma subunit family E METABOLISM Amino acid transport and metabolism ACIAD2550 CDS -2 2508595 2511516 no mgdC putative N-methyl glutamate dehydrogenase/oxidoreductase subunit C 1950 3NM8N Glycine cleavage T-protein C-terminal barrel domain E METABOLISM Amino acid transport and metabolism ACIAD2551 CDS -3 2511513 2511839 no mgdB putative N-methyl glutamate dehydrogenase/oxidoreductase subunit B 231 3NP1A Sarcosine oxidase, delta subunit family E METABOLISM Amino acid transport and metabolism ACIAD2552 CDS -3 2511852 2513090 no mgdA putative N-methyl glutamate dehydrogenase/oxidoreductase subunit A 837 3NMHX FAD dependent oxidoreductase E METABOLISM Amino acid transport and metabolism ACIAD2553 CDS -1 2513132 2514025 no folD bifunctional protein [Includes: 5,10-methylene-tetrahydrofolate dehydrogenase; 5,10-methylene-tetrahydrofolate cyclohydrolase] 579 3NKKE Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate F METABOLISM Nucleotide transport and metabolism ACIAD2554 CDS -2 2514022 2514888 no purU formyltetrahydrofolate deformylase 570 3NIE9 Catalyzes the hydrolysis of 10-formyltetrahydrofolate (formyl-FH4) to formate and tetrahydrofolate (FH4) F METABOLISM Nucleotide transport and metabolism ACIAD2555 CDS -3 2515149 2515451 no hypothetical protein 208 3NPT5 S POORLY CHARACTERIZED Function unknown ACIAD2556 CDS +3 2515737 2516777 no conserved hypothetical protein; putative 2-nitropropane dioxygenase 689 3NIKR Nitronate monooxygenase S POORLY CHARACTERIZED Function unknown ACIAD2557 CDS -2 2516779 2517804 no dusB tRNA-dihydrouridine synthase B 669 3NIZ0 Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines J INFORMATION STORAGE AND PROCESSING Translation, ribosomal structure and biogenesis ACIAD2558 CDS +2 2517887 2519098 no conserved hypothetical protein 805 3NIV9 Protein of unknown function (DUF1615) S POORLY CHARACTERIZED Function unknown ACIAD2559 CDS +1 2519101 2519718 no conserved hypothetical protein; putative phosphoserine phosphatase 411 3NJEE haloacid dehalogenase-like hydrolase E METABOLISM Amino acid transport and metabolism ACIAD2560 CDS -2 2519746 2520879 no proB gamma-glutamyl kinase 734 3NIWZ Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate E METABOLISM Amino acid transport and metabolism ACIAD2561 CDS -2 2520898 2522100 no putative GTP-binding protein (Obg) 750 3NJ8P An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control S POORLY CHARACTERIZED Function unknown ACIAD2563 CDS -2 2522248 2522928 no conserved hypothetical protein 420 3NJRM S POORLY CHARACTERIZED Function unknown ACIAD2564 CDS -3 2522937 2523674 no conserved hypothetical protein 346 3NKME S POORLY CHARACTERIZED Function unknown ACIAD2565 CDS -2 2523832 2525289 no gap glyceraldehyde-3-phosphate dehydrogenase 931 3NJM5 Belongs to the glyceraldehyde-3-phosphate dehydrogenase family G METABOLISM Carbohydrate transport and metabolism ACIAD2566 CDS -2 2525536 2526468 no rarD chloramphenicol-sensitive protein 552 3NT8G EamA-like transporter family S POORLY CHARACTERIZED Function unknown ACIAD2568 CDS -1 2526581 2527171 no putative outer membrane lipoprotein 406 3NM4V Lipocalin-like domain M CELLULAR PROCESSES AND SIGNALING Cell wall/membrane/envelope biogenesis ACIAD2569 CDS -3 2527299 2529326 no uvrB excinuclease ABC subunit B (ATP-dependent DNA excision repair enzyme UvrAC) 1296 3NJGC damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage L INFORMATION STORAGE AND PROCESSING Replication, recombination and repair ACIAD2570 CDS -1 2529407 2530099 no putative cell-cell signaling protein, C-factor (CsgA) 455 3NMUY Enoyl-(Acyl carrier protein) reductase I METABOLISM Lipid transport and metabolism ACIAD2570 CDS -1 2529407 2530099 no putative cell-cell signaling protein, C-factor (CsgA) 455 3NMUY Enoyl-(Acyl carrier protein) reductase Q METABOLISM Secondary metabolites biosynthesis, transport and catabolism ACIAD2571 CDS +1 2530282 2531115 no conserved hypothetical protein 565 3NIID DNA-templated transcription, initiation K INFORMATION STORAGE AND PROCESSING Transcription ACIAD2572 CDS +2 2531243 2532688 no putative GGDEF family protein 955 3NJU5 Motif C-terminal to PAS motifs (likely to contribute to PAS structural domain) T CELLULAR PROCESSES AND SIGNALING Signal transduction mechanisms ACIAD2573 CDS -2 2533012 2533194 no hypothetical protein 121 3NPVZ S POORLY CHARACTERIZED Function unknown ACIAD2574 CDS +1 2533408 2534640 no aspC aspartate aminotransferase A 804 3NKE8 DegT/DnrJ/EryC1/StrS aminotransferase family E METABOLISM Amino acid transport and metabolism ACIAD2575 CDS -2 2534749 2535270 no conserved hypothetical protein 367 3NNV4 S POORLY CHARACTERIZED Function unknown ACIAD2576 CDS -2 2535595 2536284 no conserved hypothetical protein; putative tRNA hydroxylase 456 3NJAF tRNA-(MS[2]IO[6]A)-hydroxylase (MiaE) F METABOLISM Nucleotide transport and metabolism ACIAD2576 CDS -2 2535595 2536284 no conserved hypothetical protein; putative tRNA hydroxylase 456 3NJAF tRNA-(MS[2]IO[6]A)-hydroxylase (MiaE) J INFORMATION STORAGE AND PROCESSING Translation, ribosomal structure and biogenesis ACIAD2577 CDS -1 2536262 2536987 no pdxJ Pyridoxine 5'-phosphate synthase 459 3NIUI Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate H METABOLISM Coenzyme transport and metabolism ACIAD2578 CDS -3 2537001 2537711 no recO DNA repair protein 472 3NJ9I Belongs to the RecO family L INFORMATION STORAGE AND PROCESSING Replication, recombination and repair ACIAD2579 CDS -1 2537723 2537923 no conserved hypothetical protein 123 3NPSD S POORLY CHARACTERIZED Function unknown ACIAD2580 CDS -1 2537936 2538973 no era GTP-binding protein,16S rRNA-binding,ribosome-associated GTPase 669 3NJHP An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism S POORLY CHARACTERIZED Function unknown ACIAD2581 CDS -2 2538979 2539671 no rnc ribonuclease III, ds RNA 451 3NJNF Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre- crRNA and tracrRNA of type II CRISPR loci if present in the organism J INFORMATION STORAGE AND PROCESSING Translation, ribosomal structure and biogenesis ACIAD2582 CDS -1 2539643 2540020 no conserved hypothetical protein; putative signal peptide 237 3NTK1 Domain of unknown function (DUF4845) N CELLULAR PROCESSES AND SIGNALING Cell motility ACIAD2582 CDS -1 2539643 2540020 no conserved hypothetical protein; putative signal peptide 237 3NTK1 Domain of unknown function (DUF4845) U CELLULAR PROCESSES AND SIGNALING Intracellular trafficking, secretion, and vesicular transport ACIAD2583 CDS -1 2540045 2540872 no lepB leader peptidase (signal peptidase I) , serine protease 578 3NIUQ Belongs to the peptidase S26 family U CELLULAR PROCESSES AND SIGNALING Intracellular trafficking, secretion, and vesicular transport ACIAD2584 CDS -1 2540891 2542708 no lepA GTP-binding protein 1175 3NK8H Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner M CELLULAR PROCESSES AND SIGNALING Cell wall/membrane/envelope biogenesis ACIAD2585 CDS -1 2542964 2543413 no putative thioesterase 311 3NN40 Acyl-ACP thioesterase S POORLY CHARACTERIZED Function unknown ACIAD2586 CDS -1 2543522 2544925 no putative serine protease MucD precursor 887 3NIKG Belongs to the peptidase S1C family O CELLULAR PROCESSES AND SIGNALING Posttranslational modification, protein turnover, chaperones ACIAD2587 CDS +1 2545135 2546769 no nadB L-aspartate oxidase (quinolinate synthetase B) 1083 3NJQX Catalyzes the oxidation of L-aspartate to iminoaspartate H METABOLISM Coenzyme transport and metabolism ACIAD2588 CDS -3 2546790 2547398 no tmk thymidylate kinase 393 3NM7P Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis F METABOLISM Nucleotide transport and metabolism ACIAD2589 CDS -3 2547408 2548481 no conserved hypothetical protein; putative periplasmic solute-binding protein 709 3NJC2 Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation S POORLY CHARACTERIZED Function unknown ACIAD2590 CDS -2 2548474 2549289 no pabC 4-amino-4-deoxychorismate lyase 554 3NIK0 Branched-chain amino acid aminotransferase 4-amino-4-deoxychorismate lyase E METABOLISM Amino acid transport and metabolism ACIAD2590 CDS -2 2548474 2549289 no pabC 4-amino-4-deoxychorismate lyase 554 3NIK0 Branched-chain amino acid aminotransferase 4-amino-4-deoxychorismate lyase H METABOLISM Coenzyme transport and metabolism ACIAD2591 CDS +1 2549449 2550450 no cysP sulfate transport protein (ABC superfamily, peri_bind) 671 3NIR3 sulfate ABC transporter P METABOLISM Inorganic ion transport and metabolism ACIAD2592 CDS +3 2550477 2551082 no conserved hypothetical protein; putative esterase of the alpha/beta hydrolase fold 420 3NKHR Serine hydrolase S POORLY CHARACTERIZED Function unknown ACIAD2594 CDS +2 2551163 2551996 no cysT sulfate transport protein (ABC superfamily, membrane) 516 3NIWN Binding-protein-dependent transport system inner membrane component O CELLULAR PROCESSES AND SIGNALING Posttranslational modification, protein turnover, chaperones ACIAD2595 CDS +1 2551960 2552883 no cysW sulfate transport protein (ABC superfamily, membrane) 583 3NJRG Binding-protein-dependent transport system inner membrane component P METABOLISM Inorganic ion transport and metabolism ACIAD2596 CDS +1 2552893 2553954 no cysA sulfate permease A protein, chromate resistance (ABC superfamily, atp_bind) 699 3NK8I Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system P METABOLISM Inorganic ion transport and metabolism ACIAD2597 CDS +2 2554007 2554930 no cbl transcriptional regulator cysteine biosynthesis (LysR family) 607 3NJT2 Transcriptional regulator K INFORMATION STORAGE AND PROCESSING Transcription ACIAD2598 CDS -2 2554990 2555730 no carO carbapenem-associated resistance protein 502 3NKCX pathogenesis S POORLY CHARACTERIZED Function unknown ACIAD2599 CDS +1 2556037 2556858 no dapD 2,3,4,5-tetrahydropyridine-2-carboxylate N-succinyltransferase 541 3NINN Belongs to the transferase hexapeptide repeat family E METABOLISM Amino acid transport and metabolism ACIAD2600 CDS +3 2556924 2557661 no putative radical activating enzyme 496 3NIYT Catalyzes the complex heterocyclic radical-mediated conversion of 6-carboxy-5,6,7,8-tetrahydropterin (CPH4) to 7- carboxy-7-deazaguanine (CDG), a step common to the biosynthetic pathways of all 7-deazapurine-containing compounds H METABOLISM Coenzyme transport and metabolism ACIAD2601 CDS +3 2557671 2558360 no queC Queuosine biosynthesis protein queC 463 3NKQJ Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0)) F METABOLISM Nucleotide transport and metabolism ACIAD2602 CDS +1 2558374 2558784 no conserved hypothetical protein; putative membrane protein 257 3NN91 S POORLY CHARACTERIZED Function unknown ACIAD2603 CDS +2 2558825 2559307 no bcp bacterioferritin comigratory protein 318 3NJ20 Redoxin O CELLULAR PROCESSES AND SIGNALING Posttranslational modification, protein turnover, chaperones ACIAD2604 CDS -1 2559371 2559949 no conserved hypothetical protein; putative signal peptide 380 3NNAZ YceI-like domain S POORLY CHARACTERIZED Function unknown ACIAD2606 CDS -1 2559995 2560561 no nadM nicotinamide/nicotinate-nucleotide adenylyltransferase 370 3NITZ Cytidylyltransferase-like H METABOLISM Coenzyme transport and metabolism ACIAD2607 CDS +2 2560661 2561461 no putative enoyl-CoA hydratase/isomerase 508 3NKFI Enoyl-CoA hydratase/isomerase I METABOLISM Lipid transport and metabolism ACIAD2608 CDS +2 2561570 2562358 no putative nitrorecductase 527 3NJZ4 Nitroreductase family C METABOLISM Energy production and conversion ACIAD2609 CDS -3 2562360 2562704 no conserved hypothetical protein 231 3NNYV protein conserved in bacteria S POORLY CHARACTERIZED Function unknown ACIAD2610 CDS +2 2562785 2564002 no putative transport protein (MFS superfamily) 807 3NIHX Uncharacterised MFS-type transporter YbfB E METABOLISM Amino acid transport and metabolism ACIAD2610 CDS +2 2562785 2564002 no putative transport protein (MFS superfamily) 807 3NIHX Uncharacterised MFS-type transporter YbfB G METABOLISM Carbohydrate transport and metabolism ACIAD2610 CDS +2 2562785 2564002 no putative transport protein (MFS superfamily) 807 3NIHX Uncharacterised MFS-type transporter YbfB P METABOLISM Inorganic ion transport and metabolism ACIAD2612 CDS -2 2564239 2568075 no purL phosphoribosylformylglycinamidine synthase (FGAM synthase) (FGAMS) (Formylglycinamide ribotide amidotransferase) (FGARAT) (Formylglycinamide ribotide synthetase) 2520 3NK3W Phosphoribosylformylglycinamidine synthase involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate F METABOLISM Nucleotide transport and metabolism ACIAD2613 CDS +3 2568330 2569664 no dgt deoxyguanosinetriphosphate triphosphohydrolase (dGTPase) (dGTP triphosphohydrolase) 909 3NJF5 Deoxyguanosinetriphosphate triphosphohydrolase-like protein F METABOLISM Nucleotide transport and metabolism ACIAD2614 CDS +2 2569766 2570380 no ruvA holliday junction helicase subunit A 384 3NIER The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB L INFORMATION STORAGE AND PROCESSING Replication, recombination and repair ACIAD2615 CDS +3 2570388 2571392 no ruvB holliday junction helicase, subunit B 652 3NIMR The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing L INFORMATION STORAGE AND PROCESSING Replication, recombination and repair ACIAD2616 CDS +2 2571470 2572105 no hypothetical protein; putative membrane protein 52.4 3NJG2 S POORLY CHARACTERIZED Function unknown ACIAD2618 CDS +2 2572373 2572804 no putative Acyl-CoA thioester hydrolase 286 3NN53 Thioesterase-like superfamily S POORLY CHARACTERIZED Function unknown ACIAD2619 CDS +3 2572830 2573528 no tolQ tolerance to group A colicins, single-stranded DNA filamentous phage, required for OM integrity 431 3NK2Q MotA/TolQ/ExbB proton channel family U CELLULAR PROCESSES AND SIGNALING Intracellular trafficking, secretion, and vesicular transport ACIAD2620 CDS +2 2573528 2573974 no tolR tolerance to group A colicins, single-stranded DNA filamentous phage, required for OM integrity 276 3NK24 Biopolymer transport protein ExbD/TolR U CELLULAR PROCESSES AND SIGNALING Intracellular trafficking, secretion, and vesicular transport ACIAD2621 CDS +2 2573978 2575288 no tolA tolerance to group A colicins, single-stranded filamentous DNA phage, required for OM integrity 315 3NKQS TonB C terminal M CELLULAR PROCESSES AND SIGNALING Cell wall/membrane/envelope biogenesis ACIAD2622 CDS +1 2575393 2576670 no tolB tolerance to colicins E2, E, A, and K, required for OM integrity 599 3NJZ9 Involved in the TonB-independent uptake of proteins U CELLULAR PROCESSES AND SIGNALING Intracellular trafficking, secretion, and vesicular transport ACIAD2623 CDS +1 2576689 2577270 no pal peptidoglycan-associated lipoprotein precursor 365 3NKBN Belongs to the ompA family M CELLULAR PROCESSES AND SIGNALING Cell wall/membrane/envelope biogenesis ACIAD2625 CDS +3 2577714 2578685 no fbp fructose-1,6-bisphosphatase 647 3NITD D-fructose-1,6-bisphosphate 1-phosphohydrolase class 1 G METABOLISM Carbohydrate transport and metabolism ACIAD2626 CDS +1 2578714 2579514 no putative tRNA/rRNA methyltransferase 525 3NSMG SpoU rRNA Methylase family J INFORMATION STORAGE AND PROCESSING Translation, ribosomal structure and biogenesis ACIAD2627 CDS +2 2579657 2580295 no putative RNA polymerase sigma factor 420 3NJEX Belongs to the sigma-70 factor family. ECF subfamily K INFORMATION STORAGE AND PROCESSING Transcription ACIAD2628 CDS +3 2580282 2580602 no conserved hypothetical protein 214 3NNW5 S POORLY CHARACTERIZED Function unknown ACIAD2629 CDS +1 2580619 2580990 no conserved hypothetical protein 168 3NNH6 Protein of unknown function (DUF3106) S POORLY CHARACTERIZED Function unknown ACIAD2630 CDS -2 2581039 2583441 no putative outer membrane protein A 1524 3NJ9R S POORLY CHARACTERIZED Function unknown ACIAD2631 CDS -2 2583451 2585274 no conserved hypothetical protein 1199 3NIYR S POORLY CHARACTERIZED Function unknown ACIAD2632 CDS -2 2585389 2586096 no putative chromosomal replication initiator, DnaA-homolog protein hda 454 3NIVI Belongs to the DnaA family L INFORMATION STORAGE AND PROCESSING Replication, recombination and repair ACIAD2633 CDS -3 2586117 2587307 no putative permease (PerM family) 726 3NM8W AI-2E family transporter S POORLY CHARACTERIZED Function unknown ACIAD2634 CDS +2 2587442 2588512 no purM phosphoribosylaminoimidazole synthetase 712 3NJMQ Phosphoribosylformylglycinamidine cyclo-ligase F METABOLISM Nucleotide transport and metabolism ACIAD2635 CDS +1 2588509 2589138 no purN phosphoribosylglycinamide formyltransferase 1 423 3NJPI Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate F METABOLISM Nucleotide transport and metabolism ACIAD2636 CDS -3 2589198 2590001 no putative hydrolase 554 3NIJF Alpha/beta hydrolase family S POORLY CHARACTERIZED Function unknown ACIAD2637 CDS -1 2590013 2591029 no putative protease; putative signal peptide peptidase sppA 651 3NJ3R signal peptide peptidase SppA O CELLULAR PROCESSES AND SIGNALING Posttranslational modification, protein turnover, chaperones ACIAD2637 CDS -1 2590013 2591029 no putative protease; putative signal peptide peptidase sppA 651 3NJ3R signal peptide peptidase SppA U CELLULAR PROCESSES AND SIGNALING Intracellular trafficking, secretion, and vesicular transport ACIAD2638 CDS +3 2591163 2592176 no putative lipid A biosynthesis lauroyl acyltransferase 669 3NIFD Bacterial lipid A biosynthesis acyltransferase M CELLULAR PROCESSES AND SIGNALING Cell wall/membrane/envelope biogenesis ACIAD2639 CDS -2 2592109 2594487 no comA competence factor involved in DNA uptake 1553 3NJVY Competence protein ComEC S POORLY CHARACTERIZED Function unknown ACIAD2640 CDS -2 2594614 2595288 no lolD transport protein of outer membrane lipoproteins (ABC superfamily, atp_bind) 441 3NJ2K Part of the ABC transporter complex LolCDE involved in the translocation of lipoproteins, in an ATP-dependent manner V CELLULAR PROCESSES AND SIGNALING Defense mechanisms ACIAD2641 CDS -1 2595293 2596528 no lolC transport protein of outer membrane lipoproteins (ABC superfamily, membrane) 770 3NIGK MacB-like periplasmic core domain M CELLULAR PROCESSES AND SIGNALING Cell wall/membrane/envelope biogenesis ACIAD2643 CDS -2 2596837 2597769 no conserved hypothetical protein; putative membrane protein 585 3NK0I EamA-like transporter family E METABOLISM Amino acid transport and metabolism ACIAD2643 CDS -2 2596837 2597769 no conserved hypothetical protein; putative membrane protein 585 3NK0I EamA-like transporter family G METABOLISM Carbohydrate transport and metabolism ACIAD2644 CDS -3 2597766 2598233 no conserved hypothetical protein 301 3NINU Belongs to the UPF0178 family S POORLY CHARACTERIZED Function unknown ACIAD2645 CDS +3 2598456 2599394 no conserved hypothetical protein 636 3NJQW S POORLY CHARACTERIZED Function unknown ACIAD2647 CDS -3 2599641 2600771 no serC 3-phosphoserine aminotransferase 746 3NKGT Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine E METABOLISM Amino acid transport and metabolism ACIAD2648 CDS +1 2601067 2602527 no conserved hypothetical protein; putative outer membrane efflux protein 899 3NIK7 Outer membrane efflux protein M CELLULAR PROCESSES AND SIGNALING Cell wall/membrane/envelope biogenesis ACIAD2648 CDS +1 2601067 2602527 no conserved hypothetical protein; putative outer membrane efflux protein 899 3NIK7 Outer membrane efflux protein U CELLULAR PROCESSES AND SIGNALING Intracellular trafficking, secretion, and vesicular transport ACIAD2649 CDS +2 2602541 2603671 no conserved hypothetical protein; putative membrane-fusion protein 679 3NIF8 Biotin-lipoyl like V CELLULAR PROCESSES AND SIGNALING Defense mechanisms ACIAD2650 CDS +1 2603674 2604804 no conserved hypothetical protein; putative membrane protein 748 3NTK2 ABC-2 family transporter protein V CELLULAR PROCESSES AND SIGNALING Defense mechanisms ACIAD2651 CDS +3 2604801 2605907 no conserved hypothetical protein; putative membrane protein 735 3NJ1W ABC-2 family transporter protein V CELLULAR PROCESSES AND SIGNALING Defense mechanisms ACIAD2652 CDS -1 2605946 2608675 no gyrA DNA gyrase, subunit A, type II topoisomerase 1731 3NJ9E A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner L INFORMATION STORAGE AND PROCESSING Replication, recombination and repair ACIAD2653 CDS -1 2608976 2609503 no conserved hypothetical protein; putative DinB protein family 357 3NNMQ DinB family S POORLY CHARACTERIZED Function unknown ACIAD2654 CDS -1 2609621 2610556 no etfA electron transfer flavoprotein alpha-subunit 573 3NIEY Electron transfer flavoprotein C METABOLISM Energy production and conversion ACIAD2655 CDS -2 2610574 2611323 no etfB electron transfer flavoprotein beta-subunit 461 3NIQV Electron transfer flavoprotein C METABOLISM Energy production and conversion ACIAD2657 CDS -3 2611761 2612678 no xerC site-specific tyrosine recombinase 602 3NIT9 Belongs to the 'phage' integrase family. XerC subfamily D CELLULAR PROCESSES AND SIGNALING Cell cycle control, cell division, chromosome partitioning ACIAD2658 CDS -3 2612685 2613326 no putative hydrolase 429 3NTIH Alpha/beta hydrolase family S POORLY CHARACTERIZED Function unknown ACIAD2659 CDS -3 2613423 2614268 no dapF diaminopimelate epimerase 570 3NIIS Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan E METABOLISM Amino acid transport and metabolism ACIAD2660 CDS -3 2614272 2615522 no lysA diaminopimelate decarboxylase 817 3NJND Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine E METABOLISM Amino acid transport and metabolism ACIAD2661 CDS -3 2615544 2615756 no lppL lipoprotein 84.3 3NPUT S POORLY CHARACTERIZED Function unknown ACIAD2662 CDS -3 2615880 2617292 no cycA D-alanine/D-serine/glycine transport protein (APC family) 897 3NJUE Amino acid permease E METABOLISM Amino acid transport and metabolism ACIAD2664 CDS +2 2617574 2618953 no radA DNA repair protein 895 3NK32 DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function O CELLULAR PROCESSES AND SIGNALING Posttranslational modification, protein turnover, chaperones ACIAD2665 CDS +2 2619224 2620246 no conserved hypothetical protein; putative membrane protein 610 3NJFM Tim44 S POORLY CHARACTERIZED Function unknown ACIAD2666 CDS -2 2620294 2621283 no putative lysyl-tRNA synthetase (Lysine--tRNA ligase)(PoxA) 647 3NJ3Z tRNA synthetases class II (D, K and N) J INFORMATION STORAGE AND PROCESSING Translation, ribosomal structure and biogenesis ACIAD2667 CDS -3 2621280 2622347 no pdxB erythronate-4-phosphate dehydrogenase 715 3NKB6 Catalyzes the oxidation of erythronate-4-phosphate to 3- hydroxy-2-oxo-4-phosphonooxybutanoate H METABOLISM Coenzyme transport and metabolism ACIAD2668 CDS -3 2622456 2622791 no conserved hypothetical protein; putative signal peptide 216 3NP2W S POORLY CHARACTERIZED Function unknown ACIAD2669 CDS +1 2623093 2624508 no antA anthranilate dioxygenase large subunit 982 3NII2 Ring hydroxylating alpha subunit (catalytic domain) P METABOLISM Inorganic ion transport and metabolism ACIAD2670 CDS +3 2624511 2625002 no antB anthranilate dioxygenase small subunit 341 3NJUB Ring hydroxylating beta subunit Q METABOLISM Secondary metabolites biosynthesis, transport and catabolism ACIAD2671 CDS +2 2625014 2626045 no antC anthranilate dioxygenase electron transfer component [Includes: Ferredoxin; Ferredoxin--NAD(+) reductase ] 702 3NK3C Oxidoreductase FAD-binding domain C METABOLISM Energy production and conversion ACIAD2672 CDS +2 2626535 2627671 no putative transcriptional regulator 765 3NT35 AraC-binding-like domain K INFORMATION STORAGE AND PROCESSING Transcription ACIAD2673 CDS -1 2627939 2628886 no conserved hypothetical protein; putative signal peptide 657 3NJSU Putative MetA-pathway of phenol degradation C METABOLISM Energy production and conversion ACIAD2674 CDS -2 2628937 2629482 no smoB styrene monooxygenase, specific NADH:flavin oxidoreductase component SmoB 365 3NKAX Flavin reductase like domain S POORLY CHARACTERIZED Function unknown ACIAD2675 CDS -1 2629502 2630743 no smoA styrene monooxygenase 849 3NMD9 oxidoreductase C METABOLISM Energy production and conversion ACIAD2676 CDS -1 2630795 2631646 no putative oxidoreductase, short-chain dehydrogenase/reductase family 539 3NKUE short-chain dehydrogenase I METABOLISM Lipid transport and metabolism ACIAD2676 CDS -1 2630795 2631646 no putative oxidoreductase, short-chain dehydrogenase/reductase family 539 3NKUE short-chain dehydrogenase Q METABOLISM Secondary metabolites biosynthesis, transport and catabolism ACIAD2677 CDS -2 2631616 2632899 no putative carboxymethylenebutenolidase (Dienelactone hydrolase) (DLH) 863 3NSQ9 Dienelactone hydrolase family Q METABOLISM Secondary metabolites biosynthesis, transport and catabolism ACIAD2678 CDS -2 2633143 2634144 no putative transcriptional regulator 683 3NJZ7 AraC-binding-like domain K INFORMATION STORAGE AND PROCESSING Transcription ACIAD2680 CDS -1 2634401 2635672 no gdh glutamate dehydrogenase (NAD(P)+) oxidoreductase protein 851 3NIYW Belongs to the Glu Leu Phe Val dehydrogenases family E METABOLISM Amino acid transport and metabolism ACIAD2681 CDS -1 2635901 2636167 no PAAR motif-containing protein (EvpJ-like) 182 3NPM0 PAAR motif S POORLY CHARACTERIZED Function unknown ACIAD2682 CDS -2 2636197 2636961 no putative outer membrane lipoprotein 483 3NK8Q OmpA family M CELLULAR PROCESSES AND SIGNALING Cell wall/membrane/envelope biogenesis ACIAD2683 CDS -3 2636964 2637923 no conserved hypothetical protein 632 3NSU8 Uncharacterized protein conserved in bacteria (DUF2094) S POORLY CHARACTERIZED Function unknown ACIAD2684 CDS -2 2637964 2641785 no putative secretion system protein (EvpO-like) 2480 3NJ4W Type VI secretion protein IcmF C-terminal S POORLY CHARACTERIZED Function unknown ACIAD2685 CDS -1 2641820 2643250 no conserved hypothetical protein; putative membrane protein 917 3NIHY beta-ketoacyl-acyl-carrier-protein synthase II activity I METABOLISM Lipid transport and metabolism ACIAD2685 CDS -1 2641820 2643250 no conserved hypothetical protein; putative membrane protein 917 3NIHY beta-ketoacyl-acyl-carrier-protein synthase II activity Q METABOLISM Secondary metabolites biosynthesis, transport and catabolism ACIAD2686 CDS -2 2643220 2644218 no putative secretion system protein (EvpG-like) 671 3NJHE overlaps another CDS with the same product name S POORLY CHARACTERIZED Function unknown ACIAD2687 CDS -3 2644182 2645990 no putative secretion system protein (EvpF-like) 1182 3NJ65 overlaps another CDS with the same product name S POORLY CHARACTERIZED Function unknown ACIAD2688 CDS -1 2646002 2646475 no putative secretion system protein (EvpE-like) 314 3NJ2P Gene 25-like lysozyme S POORLY CHARACTERIZED Function unknown ACIAD2689 CDS -1 2646545 2647048 no putative secretion system protein (EvpC-like) 340 3NJU0 Type VI secretion system effector, Hcp S POORLY CHARACTERIZED Function unknown ACIAD2690 CDS -1 2647094 2648590 no EvpB Secretion system protein EvpB 993 3NK9I Type VI secretion protein, EvpB/VC_A0108, tail sheath S POORLY CHARACTERIZED Function unknown ACIAD2691 CDS -3 2648568 2649077 no EvpA secretion system protein EvpA 287 3NJRX Type VI secretion system, VipA, VC_A0107 or Hcp2 S POORLY CHARACTERIZED Function unknown ACIAD2693 CDS -2 2649091 2649747 no conserved hypothetical protein; putative signal peptide 397 3NM54 S POORLY CHARACTERIZED Function unknown ACIAD2694 CDS +3 2650125 2652809 no putative ClpA/B-type chaperone (evpH-like) 1709 3NJIJ C-terminal, D2-small domain, of ClpB protein O CELLULAR PROCESSES AND SIGNALING Posttranslational modification, protein turnover, chaperones ACIAD2695 CDS +3 2652825 2653928 no putative secretion system protein (EvpK-like) 697 3NJVD ImpA, N-terminal, type VI secretion system S POORLY CHARACTERIZED Function unknown ACIAD2696 CDS +1 2653945 2655312 no putative secretion system protein (EvpM-like) 900 3NIZI Bacterial Type VI secretion, VC_A0110, EvfL, ImpJ, VasE S POORLY CHARACTERIZED Function unknown ACIAD2697 CDS +3 2655324 2656127 no putative secretion system protein (EvpN-like) 536 3NK1P Type VI secretion system protein DotU S POORLY CHARACTERIZED Function unknown ACIAD2698 CDS +1 2656138 2656719 no conserved hypothetical protein 66.2 3NKVV S POORLY CHARACTERIZED Function unknown ACIAD2699 CDS +2 2656820 2657683 no conserved hypothetical protein; putative membrane protein 568 3NIZ9 D-alanyl-D-alanine carboxypeptidase M CELLULAR PROCESSES AND SIGNALING Cell wall/membrane/envelope biogenesis ACIAD2700 CDS -2 2657701 2658882 no putative 2-methyl-aconitate isomerase (PrpF) 771 3NJAW PrpF protein S POORLY CHARACTERIZED Function unknown ACIAD2704 CDS +1 2660893 2661510 no conserved hypothetical protein 402 COG3209 self proteolysis M CELLULAR PROCESSES AND SIGNALING Cell wall/membrane/envelope biogenesis ACIAD2704 CDS +1 2660893 2661510 no conserved hypothetical protein 402 COG3209 self proteolysis M CELLULAR PROCESSES AND SIGNALING Cell wall/membrane/envelope biogenesis ACIAD2705 CDS +2 2661512 2661904 no hypothetical protein 70.9 1MTQA S POORLY CHARACTERIZED Function unknown ACIAD2707 CDS +2 2662166 2662330 no hypothetical protein 45.4 1RNRK Large exoproteins involved in heme utilization or adhesion U CELLULAR PROCESSES AND SIGNALING Intracellular trafficking, secretion, and vesicular transport ACIAD2708 CDS +3 2662359 2663201 no hypothetical protein 573 3NS5R S POORLY CHARACTERIZED Function unknown ACIAD2709 CDS +3 2663226 2663423 no hypothetical protein 114 3NT02 RHS Repeat M CELLULAR PROCESSES AND SIGNALING Cell wall/membrane/envelope biogenesis ACIAD2710 CDS +2 2663420 2663560 no hypothetical protein 53.5 3NJV2 COG3209 Rhs family protein M CELLULAR PROCESSES AND SIGNALING Cell wall/membrane/envelope biogenesis ACIAD2713 CDS +1 2664856 2665167 no conserved hypothetical protein 204 3NTMU Rhs Element Vgr Protein S POORLY CHARACTERIZED Function unknown ACIAD2715 CDS +2 2665640 2665873 no hypothetical protein 42.4 3NRNY S POORLY CHARACTERIZED Function unknown ACIAD2716 CDS +2 2666177 2666626 no hypothetical protein 303 3NS3M S POORLY CHARACTERIZED Function unknown ACIAD2718 fCDS -1 2667470 2667817 pseudo fragment of component of DNA polymerase V (UmuC) (part 1) 155 3NK1C DNA polymerase L INFORMATION STORAGE AND PROCESSING Replication, recombination and repair ACIAD2720 CDS -3 2667885 2668097 no hypothetical protein 56.6 3NNFB Helix-turn-helix of DDE superfamily endonuclease S POORLY CHARACTERIZED Function unknown ACIAD2721 CDS -2 2668408 2669565 no conserved hypothetical protein; putative hydrolase/monooxygenase 772 3NKZF FAD binding domain C METABOLISM Energy production and conversion ACIAD2722 CDS -2 2669590 2669835 no putative multidrug resistance efflux pump 164 COG1566 PFAM secretion protein HlyD family protein V CELLULAR PROCESSES AND SIGNALING Defense mechanisms ACIAD2722 CDS -2 2669590 2669835 no putative multidrug resistance efflux pump 164 COG1566 PFAM secretion protein HlyD family protein V CELLULAR PROCESSES AND SIGNALING Defense mechanisms ACIAD2723 CDS -2 2669836 2670441 no putative hydrolase 387 3NJZI Isochorismatase family Q METABOLISM Secondary metabolites biosynthesis, transport and catabolism ACIAD2724 CDS -2 2670466 2671197 no putative PIRIN-like protein 491 1RNVM Belongs to the pirin family S POORLY CHARACTERIZED Function unknown ACIAD2725 CDS -3 2671209 2672282 no putative oxidoreductase, NADH-dependent flavin oxidoreductase 720 3NKMZ NADH:flavin oxidoreductase / NADH oxidase family C METABOLISM Energy production and conversion ACIAD2727 CDS +1 2672578 2673465 no putative transcriptional regulator 588 3NT55 LysR substrate binding domain K INFORMATION STORAGE AND PROCESSING Transcription ACIAD2728 fCDS -3 2673741 2673935 pseudo fragment of component of DNA polymerase V (UmuC) (part 2) 70.1 3NK1C DNA polymerase L INFORMATION STORAGE AND PROCESSING Replication, recombination and repair ACIAD2729 CDS -1 2673896 2674507 no umuD component of DNA polymerase V 404 3NM3U Peptidase S24-like K INFORMATION STORAGE AND PROCESSING Transcription ACIAD2729 CDS -1 2673896 2674507 no umuD component of DNA polymerase V 404 3NM3U Peptidase S24-like T CELLULAR PROCESSES AND SIGNALING Signal transduction mechanisms ACIAD2730 CDS +1 2674651 2674896 no ddrR RecA-dependent DNA damage-inducible protein 170 3NPBZ S POORLY CHARACTERIZED Function unknown ACIAD2731 CDS -3 2675103 2675543 no conserved hypothetical protein 295 3NJDA Thioesterase superfamily Q METABOLISM Secondary metabolites biosynthesis, transport and catabolism ACIAD2734 CDS -2 2675995 2676648 no conserved hypothetical protein 412 3NM71 ABC-type transport auxiliary lipoprotein component S POORLY CHARACTERIZED Function unknown ACIAD2735 CDS -1 2676704 2678377 no pqiB paraquat-inducible protein 1077 3NKNI MlaD protein Q METABOLISM Secondary metabolites biosynthesis, transport and catabolism ACIAD2736 CDS -3 2678403 2679194 no pqiA-2 paraquat-inducible protein A (part 2) 513 3NK68 Paraquat-inducible protein A S POORLY CHARACTERIZED Function unknown ACIAD2737 CDS -1 2679182 2679877 no pqiA-1 paraquat-inducible protein A (part 1) 421 3NJG9 Paraquat-inducible protein A S POORLY CHARACTERIZED Function unknown ACIAD2738 CDS -1 2680379 2681362 no putative NADPH:quinone reductase and related Zn-dependent oxidoreductase 635 3NT08 Zinc-binding dehydrogenase C METABOLISM Energy production and conversion ACIAD2739 CDS -2 2681407 2682087 no conserved hypothetical protein 455 3NIXP DJ-1/PfpI family S POORLY CHARACTERIZED Function unknown ACIAD2740 CDS -3 2682084 2682713 no putative transcriptional regulator (TetR/AcrR family) 416 3NKFY Bacterial transcriptional repressor C-terminal K INFORMATION STORAGE AND PROCESSING Transcription ACIAD2741 CDS -3 2683035 2684903 no conserved hypothetical protein 1290 3NIMI Glycoside hydrolase family 24 S POORLY CHARACTERIZED Function unknown ACIAD2742 CDS -1 2685080 2686036 no putative transcriptional regulator 638 3NIP0 LysR substrate binding domain K INFORMATION STORAGE AND PROCESSING Transcription ACIAD2743 CDS +1 2686126 2686767 no putative amino acid efflux transmembrane protein 414 3NK22 LysE type translocator E METABOLISM Amino acid transport and metabolism ACIAD2745 CDS +2 2686895 2687617 no putative TPR repeat-containing protein 197 3NN5N COG0790 FOG TPR repeat, SEL1 subfamily S POORLY CHARACTERIZED Function unknown ACIAD2746 CDS -1 2687693 2688538 no conserved hypothetical protein; putative membrane protein 538 3NJJ3 EamA-like transporter family E METABOLISM Amino acid transport and metabolism ACIAD2746 CDS -1 2687693 2688538 no conserved hypothetical protein; putative membrane protein 538 3NJJ3 EamA-like transporter family G METABOLISM Carbohydrate transport and metabolism ACIAD2748 CDS -2 2688787 2689656 no putative peroxidase/hydrolase 583 3NJ6V Serine aminopeptidase, S33 I METABOLISM Lipid transport and metabolism ACIAD2749 CDS +1 2690008 2690187 no hypothetical protein 120 3NSE3 S POORLY CHARACTERIZED Function unknown ACIAD2750 CDS -1 2690171 2690371 no hypothetical protein 56.6 3NQ81 S POORLY CHARACTERIZED Function unknown ACIAD2751 CDS -2 2690806 2690949 no hypothetical protein 108 3NPS0 Zinc-ribbon containing domain S POORLY CHARACTERIZED Function unknown ACIAD2752 CDS -2 2691295 2691774 no hypothetical protein; putative membrane protein 311 1SAEH Protein of unknown function (DUF2569) E METABOLISM Amino acid transport and metabolism ACIAD2752 CDS -2 2691295 2691774 no hypothetical protein; putative membrane protein 311 1SAEH Protein of unknown function (DUF2569) G METABOLISM Carbohydrate transport and metabolism ACIAD2753 CDS -3 2692170 2693006 no conserved hypothetical protein 553 3NN8E S POORLY CHARACTERIZED Function unknown ACIAD2754 CDS -1 2693036 2693314 no conserved hypothetical protein 181 3NQ0Z S POORLY CHARACTERIZED Function unknown ACIAD2755 CDS -1 2693333 2695966 no putative methyl-cis-aconitic acid hydratase (AcnM) 1735 3NK4I Catalyzes the isomerization of citrate to isocitrate via cis-aconitate C METABOLISM Energy production and conversion ACIAD2756 CDS -2 2695966 2697060 no prpC methylcitrate synthase (citrate synthase 2) 728 3NKGX Belongs to the citrate synthase family C METABOLISM Energy production and conversion ACIAD2758 CDS -2 2697340 2698224 no prpB methylisocitrate lyase 555 3NJAS Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate G METABOLISM Carbohydrate transport and metabolism ACIAD2759 CDS -3 2698248 2698994 no putative transcriptional regulator (GntR family) 484 3NIUU FCD K INFORMATION STORAGE AND PROCESSING Transcription ACIAD2761 CDS -1 2699483 2700823 no fbsQ putative multidrug resistance pump 829 3NMR6 MatE V CELLULAR PROCESSES AND SIGNALING Defense mechanisms ACIAD2762 CDS -1 2700863 2702014 no fbsP siderophore-interacting protein 769 3NMGA Protein of unknown function (DUF2470) P METABOLISM Inorganic ion transport and metabolism ACIAD2763 CDS -2 2702041 2703264 no fbsO putative transport protein (MFS superfamily) 767 3NJ30 Acetyl-coenzyme A transporter 1 E METABOLISM Amino acid transport and metabolism ACIAD2763 CDS -2 2702041 2703264 no fbsO putative transport protein (MFS superfamily) 767 3NJ30 Acetyl-coenzyme A transporter 1 G METABOLISM Carbohydrate transport and metabolism ACIAD2763 CDS -2 2702041 2703264 no fbsO putative transport protein (MFS superfamily) 767 3NJ30 Acetyl-coenzyme A transporter 1 P METABOLISM Inorganic ion transport and metabolism ACIAD2764 CDS -3 2703300 2705447 no fbsN putative ferric siderophore receptor protein 1423 3NTJZ TonB-dependent Receptor Plug Domain P METABOLISM Inorganic ion transport and metabolism ACIAD2765 CDS +1 2705698 2706438 no fbsM putative thioesterase 493 3NT8C Thioesterase domain Q METABOLISM Secondary metabolites biosynthesis, transport and catabolism ACIAD2766 CDS +1 2706463 2707290 no fbsL phosphopantetheinyl transferase component of siderophore synthetase 545 3NNAD 4'-phosphopantetheinyl transferase superfamily Q METABOLISM Secondary metabolites biosynthesis, transport and catabolism ACIAD2767 CDS -1 2707493 2708080 no fbsK putative siderophore biosynthesis protein; putative acetyltransferase 402 3NJJX Siderophore biosynthesis protein domain J INFORMATION STORAGE AND PROCESSING Translation, ribosomal structure and biogenesis ACIAD2768 CDS -2 2708185 2709345 no fbsJ putative ornithine decarboxylase 775 3NK2X Belongs to the Orn Lys Arg decarboxylase class-II family E METABOLISM Amino acid transport and metabolism ACIAD2769 CDS -2 2709355 2710695 no fbsI putative siderophore biosynthesis protein; putative Lysine/ornithine N-monooxygenase 913 3NIYD L-lysine 6-monooxygenase (NADPH-requiring) Q METABOLISM Secondary metabolites biosynthesis, transport and catabolism ACIAD2770 CDS -1 2710709 2712328 no fbsH 2,3-dihydroxybenzoate-AMP ligase 1082 3NMAP AMP-binding enzyme C-terminal domain Q METABOLISM Secondary metabolites biosynthesis, transport and catabolism ACIAD2771 CDS -1 2712341 2715541 no fbsG putative nonribosomal peptide synthetase with phosphopantetheine-binding domain 2086 3NJMH Condensation domain Q METABOLISM Secondary metabolites biosynthesis, transport and catabolism ACIAD2772 CDS -1 2715557 2718802 no fbsF putative non-ribosomal peptide synthetase with condensation, AMP-binding and phosphopantetheine-binding domains 2137 3NSZT AMP-binding enzyme C-terminal domain Q METABOLISM Secondary metabolites biosynthesis, transport and catabolism ACIAD2773 CDS -2 2718805 2721297 no fbsE non-ribosomal peptide synthetase 1645 3NM27 Pfam:NRPS Q METABOLISM Secondary metabolites biosynthesis, transport and catabolism ACIAD2774 CDS -2 2721313 2722098 no fbsD 2,3-dihydro-2,3-dihydroxybenzoate dehydrogenase 514 3NMRM Enoyl-(Acyl carrier protein) reductase I METABOLISM Lipid transport and metabolism ACIAD2774 CDS -2 2721313 2722098 no fbsD 2,3-dihydro-2,3-dihydroxybenzoate dehydrogenase 514 3NMRM Enoyl-(Acyl carrier protein) reductase Q METABOLISM Secondary metabolites biosynthesis, transport and catabolism ACIAD2775 CDS -2 2722126 2722755 no fbsC 2,3-dihydro-2,3-dihydroxybenzoate synthetase, isochorismatase 427 3NIS0 Isochorismatase family Q METABOLISM Secondary metabolites biosynthesis, transport and catabolism ACIAD2776 CDS -2 2722849 2724036 no fbsB isochorismate synthetase 778 3NMCH chorismate binding enzyme H METABOLISM Coenzyme transport and metabolism ACIAD2776 CDS -2 2722849 2724036 no fbsB isochorismate synthetase 778 3NMCH chorismate binding enzyme Q METABOLISM Secondary metabolites biosynthesis, transport and catabolism ACIAD2778 CDS -2 2724769 2725713 no fbsA transcriptional regulator (AraC family) 627 3NKPV helix_turn_helix, arabinose operon control protein K INFORMATION STORAGE AND PROCESSING Transcription ACIAD2779 fCDS -3 2726460 2726675 pseudo fragment of transposase of IS1236, IS3 family (ORF 2) (part 4) 131 3NKN1 Evidence 1 Function experimentally demonstrated in the studied organism L INFORMATION STORAGE AND PROCESSING Replication, recombination and repair ACIAD2780 fCDS -1 2726672 2726926 pseudo fragment of transposase of IS1236, IS3 family (ORF 2) (part 3) 159 3NKN1 Evidence 1 Function experimentally demonstrated in the studied organism L INFORMATION STORAGE AND PROCESSING Replication, recombination and repair ACIAD2781 fCDS -1 2726933 2727184 pseudo fragment of transposase of IS1236, IS3 family (ORF 2) (part 2) 152 3NKN1 Evidence 1 Function experimentally demonstrated in the studied organism L INFORMATION STORAGE AND PROCESSING Replication, recombination and repair ACIAD2782 fCDS -2 2727343 2727537 pseudo fragment of transposase of IS1236, IS3 family (ORF 1) (part 1) 119 3NNW1 Evidence 1 Function experimentally demonstrated in the studied organism L INFORMATION STORAGE AND PROCESSING Replication, recombination and repair ACIAD2783 CDS -3 2727816 2729189 no putative immunity protein CdiI 945 3NMCC S POORLY CHARACTERIZED Function unknown ACIAD2784 CDS -3 2729202 2735204 no cdiA toxin CdiA 3699 3NK7X Large exoproteins involved in heme utilization or adhesion U CELLULAR PROCESSES AND SIGNALING Intracellular trafficking, secretion, and vesicular transport ACIAD2785 CDS -1 2735297 2737063 no putative outer membrane transporter CdiB 1180 3NMBZ POTRA domain U CELLULAR PROCESSES AND SIGNALING Intracellular trafficking, secretion, and vesicular transport ACIAD2788 CDS -3 2737896 2739158 no putative transport of long-chain fatty acids 854 3NKKQ long-chain fatty acid transport protein I METABOLISM Lipid transport and metabolism ACIAD2789 CDS -1 2739326 2740057 no conserved hypothetical protein DUF4386 471 3NMTT S POORLY CHARACTERIZED Function unknown ACIAD2790 CDS -3 2740002 2741375 no putative oxidoreductase 931 3NSNV FAD dependent oxidoreductase E METABOLISM Amino acid transport and metabolism ACIAD2793 CDS -1 2741744 2742349 no putative transcriptional regulator (TetR family) 395 3NKUC Bacterial regulatory proteins, tetR family K INFORMATION STORAGE AND PROCESSING Transcription ACIAD2794 CDS +3 2742813 2744345 no putative Baeyer-Villiger monooxygenase (EthA-like) 1045 3NN0P Flavin-binding monooxygenase-like P METABOLISM Inorganic ion transport and metabolism ACIAD2795 CDS +1 2744428 2745342 no putative hydrolase of the alpha/beta superfamily 609 3NMQF Acetyl xylan esterase (AXE1) S POORLY CHARACTERIZED Function unknown ACIAD2796 CDS +1 2745343 2745522 no hypothetical protein 117 3NRXJ carboxylic ester hydrolase activity I METABOLISM Lipid transport and metabolism ACIAD2797 CDS +1 2745532 2745624 no hypothetical protein 52.4 3NRXJ carboxylic ester hydrolase activity I METABOLISM Lipid transport and metabolism ACIAD2799 CDS -2 2745769 2746221 no putative phage-type endonuclease domain protein 312 3NIIT YqaJ-like viral recombinase domain L INFORMATION STORAGE AND PROCESSING Replication, recombination and repair ACIAD2800 CDS -2 2746270 2746494 no hypothetical protein 58.5 3NIIT YqaJ-like viral recombinase domain L INFORMATION STORAGE AND PROCESSING Replication, recombination and repair ACIAD2801 CDS -1 2746604 2747488 no conserved hypothetical protein 575 3NJ4Z Domain of unknown function (DUF932) S POORLY CHARACTERIZED Function unknown ACIAD2802 CDS -3 2747694 2748146 no hypothetical protein 298 3NSJ0 S POORLY CHARACTERIZED Function unknown ACIAD2805 CDS -3 2748879 2749154 no hypothetical protein 185 3NPMW S POORLY CHARACTERIZED Function unknown ACIAD2807 CDS -3 2749479 2749832 no hypothetical protein 236 3NQ2H S POORLY CHARACTERIZED Function unknown ACIAD2808 CDS +2 2750276 2750638 no hypothetical protein 60.1 3NQCW S POORLY CHARACTERIZED Function unknown ACIAD2809 CDS +1 2750734 2751462 no hypothetical protein; putative membrane protein 473 3NN5I Protein of unknown function (DUF805) S POORLY CHARACTERIZED Function unknown ACIAD2810 CDS -3 2751696 2751992 no hypothetical protein 204 3NQ0D S POORLY CHARACTERIZED Function unknown ACIAD2814 CDS -2 2753071 2753544 no greB transcription elongation factor and transcript cleavage 313 3NIG3 Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreB releases sequences of up to 9 nucleotides in length K INFORMATION STORAGE AND PROCESSING Transcription ACIAD2815 CDS -2 2753611 2754060 no conserved hypothetical protein 300 3NMIX carboxylic ester hydrolase activity I METABOLISM Lipid transport and metabolism ACIAD2817 CDS -1 2754416 2755177 no putative transcriptional regulator (IcIR family) 485 3NJSA helix_turn_helix isocitrate lyase regulation K INFORMATION STORAGE AND PROCESSING Transcription ACIAD2818 CDS -1 2755319 2756590 no citN citrate transporter 800 3NMSD Citrate transporter C METABOLISM Energy production and conversion ACIAD2819 CDS -2 2756626 2757552 no putative gluconolactonase 647 1RZMF gluconolactonase G METABOLISM Carbohydrate transport and metabolism ACIAD2820 CDS +1 2757745 2758725 no putative hydroxymethylglutaryl-CoA lyase 645 3NM36 HMGL-like E METABOLISM Amino acid transport and metabolism ACIAD2821 CDS +2 2758727 2759926 no putative CoA transferase 804 3NK4S CoA-transferase family III C METABOLISM Energy production and conversion ACIAD2822 CDS +2 2759945 2761282 no putative transport protein (MFS superfamily) 881 3NKFR COG0477 Permeases of the major facilitator superfamily G METABOLISM Carbohydrate transport and metabolism ACIAD2824 CDS +2 2761442 2762740 no conserved hypothetical protein; putative protein (DcaP-like) 850 3NK4E Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane M CELLULAR PROCESSES AND SIGNALING Cell wall/membrane/envelope biogenesis ACIAD2824 CDS +2 2761442 2762740 no conserved hypothetical protein; putative protein (DcaP-like) 850 3NK4E Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane U CELLULAR PROCESSES AND SIGNALING Intracellular trafficking, secretion, and vesicular transport ACIAD2825 fCDS +3 2762865 2763038 pseudo fragment of transcription elongation factor (GreB-like) (part 1) 67 3NIG3 Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreB releases sequences of up to 9 nucleotides in length K INFORMATION STORAGE AND PROCESSING Transcription ACIAD2826 fCDS +2 2763125 2763325 pseudo fragment of transcription elongation factor (GreB-like) (part 2) 50.4 3NIG3 Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreB releases sequences of up to 9 nucleotides in length K INFORMATION STORAGE AND PROCESSING Transcription ACIAD2827 CDS +3 2763954 2765066 no putative periplasmic binding protein of transport/transglycosylase 745 3NISE Transglycosylase SLT domain M CELLULAR PROCESSES AND SIGNALING Cell wall/membrane/envelope biogenesis ACIAD2828 CDS -2 2765143 2765526 no conserved hypothetical protein 245 3NN8A SCP-2 sterol transfer family I METABOLISM Lipid transport and metabolism ACIAD2829 CDS -3 2765736 2766641 no conserved hypothetical protein 607 3NJFF Catalyzes the ATP-dependent 2-thiolation of cytidine in position 32 of tRNA, to form 2-thiocytidine (s(2)C32). The sulfur atoms are provided by the cysteine cysteine desulfurase (IscS) system D CELLULAR PROCESSES AND SIGNALING Cell cycle control, cell division, chromosome partitioning ACIAD2832 CDS +3 2767146 2767997 no putative transglycosylase 564 3NJTE Transglycosylase SLT domain M CELLULAR PROCESSES AND SIGNALING Cell wall/membrane/envelope biogenesis ACIAD2833 CDS +1 2768149 2769054 no htpX heat shock protein 575 3NIJP Belongs to the peptidase M48B family O CELLULAR PROCESSES AND SIGNALING Posttranslational modification, protein turnover, chaperones ACIAD2834 CDS -1 2769092 2769712 no conserved hypothetical protein; putative membrane protein 408 3NT75 Domain of unknown function (DUF4112) S POORLY CHARACTERIZED Function unknown ACIAD2835 CDS -1 2769722 2771098 no putative Mg transporter (MgtE) 837 3NIPA Acts as a magnesium transporter P METABOLISM Inorganic ion transport and metabolism ACIAD2836 CDS -1 2771273 2774401 no putative multidrug efflux protein 1965 3NIHE AcrB/AcrD/AcrF family U CELLULAR PROCESSES AND SIGNALING Intracellular trafficking, secretion, and vesicular transport ACIAD2837 CDS +2 2774639 2775034 no dgkA diacylglycerol kinase 247 3NNIC Recycling of diacylglycerol produced during the turnover of membrane phospholipid M CELLULAR PROCESSES AND SIGNALING Cell wall/membrane/envelope biogenesis ACIAD2838 CDS -1 2775302 2776936 no groEL chaperone Hsp60, peptide-dependent ATPase, heat shock protein 993 3NIS9 Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions O CELLULAR PROCESSES AND SIGNALING Posttranslational modification, protein turnover, chaperones ACIAD2839 CDS -1 2776997 2777287 no groES chaperone Hsp10, affects cell division 185 3NNVH Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter O CELLULAR PROCESSES AND SIGNALING Posttranslational modification, protein turnover, chaperones ACIAD2840 CDS -1 2777468 2778244 no putative 3',5'-cyclic-nucleotide phosphodiesterase 542 3NKKS Calcineurin-like phosphoesterase superfamily domain S POORLY CHARACTERIZED Function unknown ACIAD2841 CDS -3 2778225 2779166 no conserved hypothetical protein 609 3NJNZ Diacylglycerol kinase catalytic domain (presumed) I METABOLISM Lipid transport and metabolism ACIAD2842 CDS +1 2779570 2781399 no pckG phosphoenolpyruvate carboxykinase [GTP] (PEP carboxykinase) (PEPCK) 1269 3NK9R Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP), the rate-limiting step in the metabolic pathway that produces glucose from lactate and other precursors derived from the citric acid cycle H METABOLISM Coenzyme transport and metabolism ACIAD2843 CDS +1 2781523 2781909 no hypothetical protein; putative signal peptide 255 3NNQQ S POORLY CHARACTERIZED Function unknown ACIAD2844 CDS -3 2781978 2783501 no glpD glycerol-3-phosphate dehydrogenase 1009 3NJM2 C-terminal domain of alpha-glycerophosphate oxidase C METABOLISM Energy production and conversion ACIAD2845 CDS +1 2783701 2784129 no conserved hypothetical protein; putative signal peptide 277 3NN5S S POORLY CHARACTERIZED Function unknown ACIAD2846 CDS -2 2784157 2784825 no conserved hypothetical protein 459 3NIFE Lysine methyltransferase S POORLY CHARACTERIZED Function unknown ACIAD2847 CDS -2 2785081 2785929 no folD bifunctional protein [Includes: 5,10-methylene-tetrahydrofolate dehydrogenase; 5,10-methylene-tetrahydrofolate cyclohydrolase] 538 3NIEZ Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate F METABOLISM Nucleotide transport and metabolism ACIAD2849 CDS -1 2786366 2786614 no hypothetical protein; putative membrane protein 47.8 3NQ2Y S POORLY CHARACTERIZED Function unknown ACIAD2850 CDS +2 2786714 2787877 no glxK glycerate kinase 759 3NJ2Y Belongs to the glycerate kinase type-1 family G METABOLISM Carbohydrate transport and metabolism ACIAD2851 CDS -2 2788453 2788773 no conserved hypothetical protein 212 3NNVQ S POORLY CHARACTERIZED Function unknown ACIAD2852 CDS -3 2788851 2789702 no folP 7,8-dihydropteroate synthase 555 3NJMW Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives H METABOLISM Coenzyme transport and metabolism ACIAD2853 CDS -1 2789831 2791726 no ftsH cell division protein 1196 3NIUT Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins O CELLULAR PROCESSES AND SIGNALING Posttranslational modification, protein turnover, chaperones ACIAD2854 CDS -3 2791860 2792510 no ftsJ cell division protein (filamentous temperature sensitivity, 23S rRNA U2552 ribose 2'-O-methyltransferase, SAM-dependent) 418 3NJ2H Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit J INFORMATION STORAGE AND PROCESSING Translation, ribosomal structure and biogenesis ACIAD2855 CDS +2 2792708 2793034 no putative RNA-binding protein 205 3NT6Q CRS1_YhbY J INFORMATION STORAGE AND PROCESSING Translation, ribosomal structure and biogenesis ACIAD2856 CDS +2 2793047 2793583 no conserved hypothetical protein 375 3NIH5 S POORLY CHARACTERIZED Function unknown ACIAD2857 CDS -1 2793620 2794048 no conserved hypothetical protein 258 3NKI9 S POORLY CHARACTERIZED Function unknown ACIAD2860 CDS +2 2794394 2795533 no carA carbamoyl-phosphate synthase, small chain 771 3NJIR Belongs to the CarA family F METABOLISM Nucleotide transport and metabolism ACIAD2861 CDS +1 2795548 2798781 no carB carbamoyl-phosphate synthase, large subunit 2133 3NIFC Carbamoyl-phosphate synthetase ammonia chain F METABOLISM Nucleotide transport and metabolism ACIAD2862 CDS +3 2798871 2799347 no greA transcription elongation factor, cleaves 3' nucleotide of paused mRNA 302 3NKAV Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides K INFORMATION STORAGE AND PROCESSING Transcription ACIAD2863 CDS +2 2799491 2799949 no putative universal stress protein A (UspA) 286 1SEXH Universal stress protein T CELLULAR PROCESSES AND SIGNALING Signal transduction mechanisms ACIAD2864 CDS -1 2799971 2800372 no putative methyltransferase 269 3NPDQ 6-O-methylguanine DNA methyltransferase, DNA binding domain L INFORMATION STORAGE AND PROCESSING Replication, recombination and repair ACIAD2865 CDS +3 2800542 2800991 no Putative universal stress protein UspA 285 3NP0V Universal stress protein T CELLULAR PROCESSES AND SIGNALING Signal transduction mechanisms ACIAD2866 CDS -2 2801143 2806320 no bap biofilm associated protein 3158 3NTMV TIGRFAM Outer membrane protein N CELLULAR PROCESSES AND SIGNALING Cell motility ACIAD2866 CDS -2 2801143 2806320 no bap biofilm associated protein 3158 3NTMV TIGRFAM Outer membrane protein U CELLULAR PROCESSES AND SIGNALING Intracellular trafficking, secretion, and vesicular transport ACIAD2867 CDS -1 2806793 2808292 no putative Na+/H+ antiporter 959 3NKNJ Sodium/hydrogen exchanger family P METABOLISM Inorganic ion transport and metabolism ACIAD2868 CDS +1 2808487 2809044 no hypothetical protein; putative membrane protein 362 3NNKZ S POORLY CHARACTERIZED Function unknown ACIAD2869 CDS -2 2809069 2809965 no conserved hypothetical protein; putative membrane protein 571 3NKKT Putative neutral zinc metallopeptidase S POORLY CHARACTERIZED Function unknown ACIAD2870 CDS -2 2810002 2810916 no conserved hypothetical protein; putative membrane protein 549 3NIU6 Protein of unknown function (DUF808) S POORLY CHARACTERIZED Function unknown ACIAD2871 CDS +2 2811122 2812135 no trpS tryptophanyl-tRNA synthetase 666 3NIKH Belongs to the class-I aminoacyl-tRNA synthetase family J INFORMATION STORAGE AND PROCESSING Translation, ribosomal structure and biogenesis ACIAD2872 CDS -2 2812543 2813433 no sucD succinyl-CoA synthetase alpha chain 580 3NKDR Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit C METABOLISM Energy production and conversion ACIAD2873 CDS -1 2813447 2814613 no sucC succinyl-CoA synthetase beta chain 725 3NJCK Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit F METABOLISM Nucleotide transport and metabolism ACIAD2874 CDS -1 2814788 2816221 no lpd dihydrolipoamide dehydrogenase E3 subunit of 2-oxoglutarate dehydrogenase complex (Glycine oxidation system L-factor) 937 3NIRD COG1249 Pyruvate 2-oxoglutarate dehydrogenase complex, dihydrolipoamide dehydrogenase (E3) component, and related enzymes C METABOLISM Energy production and conversion ACIAD2875 CDS -1 2816279 2817487 no sucB dihydrolipoamide succinyltransferase, E2 component of 2-oxoglutarate dehydrogenase complex 677 3NIMS The 2-oxoglutarate dehydrogenase complex catalyzes the overall conversion of 2-oxoglutarate to succinyl-CoA and CO(2) C METABOLISM Energy production and conversion ACIAD2876 CDS -2 2817487 2820327 no sucA 2-oxoglutarate decarboxylase E1 component of the 2-oxoglutarate dehydrogenase complex 1882 3NIYG COG0567 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, and related enzymes C METABOLISM Energy production and conversion ACIAD2879 CDS -3 2820882 2821592 no sdhB succinate dehydrogenase, iron-sulfur subunit 502 3NIGB succinate dehydrogenase C METABOLISM Energy production and conversion ACIAD2880 CDS -3 2821608 2823506 no sdhA succinate dehydrogenase, flavoprotein subunit 1281 3NJNU Belongs to the FAD-dependent oxidoreductase 2 family. FRD SDH subfamily C METABOLISM Energy production and conversion ACIAD2881 CDS -3 2823519 2823884 no sdhD succinate dehydrogenase, hydrophobic subunit 241 3NNHR Succinate dehydrogenase hydrophobic membrane anchor subunit C METABOLISM Energy production and conversion ACIAD2882 CDS -1 2823884 2824285 no sdhC succinate dehydrogenase, cytochrome b556 subunit 243 3NNJ6 succinate dehydrogenase C METABOLISM Energy production and conversion ACIAD2886 CDS +3 2825328 2826602 no gltA citrate synthase 854 3NKP2 Belongs to the citrate synthase family C METABOLISM Energy production and conversion ACIAD2887 CDS -1 2826671 2827132 no conserved hypothetical protein 315 3NNZR S POORLY CHARACTERIZED Function unknown ACIAD2888 CDS +1 2827405 2829030 no nadE NAD synthetase, NH3/glutamine-dependent 1058 3NIYF Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source H METABOLISM Coenzyme transport and metabolism ACIAD2889 CDS +2 2829023 2830060 no conserved hypothetical protein 669 3NIXS S POORLY CHARACTERIZED Function unknown ACIAD2890 CDS -2 2830114 2831292 no conserved hypothetical protein; putative signal peptide 816 3NM0Q hemolysin activation secretion protein U CELLULAR PROCESSES AND SIGNALING Intracellular trafficking, secretion, and vesicular transport ACIAD2892 CDS -2 2832265 2832528 no putative ferredoxin [4Fe-4S] (Fdx) 190 3NPI1 Ferredoxin C METABOLISM Energy production and conversion ACIAD2893 CDS -1 2832530 2833021 no coaD phosphopantetheine adenylyltransferase 327 3NJTZ Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate H METABOLISM Coenzyme transport and metabolism ACIAD2894 CDS +2 2833163 2833639 no smpB ssrA-binding protein (Small protein B) 314 3NIK8 the 2 termini fold to resemble tRNA(Ala) and it encodes a tag peptide , a short internal open reading frame. During trans-translation Ala- aminoacylated tmRNA acts like a tRNA, entering the A-site of stalled ribosomes, displacing the stalled mRNA. The ribosome then switches to translate the ORF on the tmRNA O CELLULAR PROCESSES AND SIGNALING Posttranslational modification, protein turnover, chaperones ACIAD2895 CDS -2 2833681 2834232 no conserved hypothetical protein; putative flavodoxin or tryptophan repressor binding protein 378 3NTMW Flavodoxin domain S POORLY CHARACTERIZED Function unknown ACIAD2896 CDS -1 2834273 2835013 no conserved hypothetical protein 507 3NIMQ Belongs to the multicopper oxidase YfiH RL5 family S POORLY CHARACTERIZED Function unknown ACIAD2897 CDS -2 2835028 2836080 no rluD ribosomal large subunit pseudouridine synthase D (Pseudouridylate synthase) (Uracil hydrolyase) 688 3NJP8 Responsible for synthesis of pseudouridine from uracil J INFORMATION STORAGE AND PROCESSING Translation, ribosomal structure and biogenesis ACIAD2898 CDS +1 2836153 2837208 no putative competence protein (ComL) 684 3NJGY Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane M CELLULAR PROCESSES AND SIGNALING Cell wall/membrane/envelope biogenesis ACIAD2899 CDS +2 2837360 2839249 no dnaG DNA primase 1252 3NIVT RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication L INFORMATION STORAGE AND PROCESSING Replication, recombination and repair ACIAD2900 CDS -3 2839251 2840546 no hemA glutamyl tRNA reductase 820 3NJ4K Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA) H METABOLISM Coenzyme transport and metabolism ACIAD2901 CDS +3 2840634 2842337 no conserved hypothetical protein; putative signal peptide 1082 3NJFB COG0457 FOG TPR repeat N CELLULAR PROCESSES AND SIGNALING Cell motility ACIAD2901 CDS +3 2840634 2842337 no conserved hypothetical protein; putative signal peptide 1082 3NJFB COG0457 FOG TPR repeat U CELLULAR PROCESSES AND SIGNALING Intracellular trafficking, secretion, and vesicular transport ACIAD2902 CDS +3 2842341 2842922 no lolB outer-membrane lipoprotein precursor 385 3NJDU Plays a critical role in the incorporation of lipoproteins in the outer membrane after they are released by the LolA protein M CELLULAR PROCESSES AND SIGNALING Cell wall/membrane/envelope biogenesis ACIAD2903 CDS +2 2842937 2843776 no ispE 4-diphosphocytidyl-2-C-methyl-D-erythritol kinase (CMK) (4-(cytidine-5'-diphospho)-2-C-methyl-D-erythritol kinase) 564 3NJU8 Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol F METABOLISM Nucleotide transport and metabolism ACIAD2907 CDS +1 2844457 2845410 no prs ribose-phosphate pyrophosphokinase (Phosphoribosyl pyrophosphate synthetase) 612 3NIWP Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P) F METABOLISM Nucleotide transport and metabolism ACIAD2908 CDS +3 2845494 2845805 no rplY 50S ribosomal protein L25 199 3NNWM This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance J INFORMATION STORAGE AND PROCESSING Translation, ribosomal structure and biogenesis ACIAD2909 CDS +2 2845826 2846407 no pth peptidyl-tRNA hydrolase 400 3NIT4 The natural substrate for this enzyme may be peptidyl- tRNAs which drop off the ribosome during protein synthesis J INFORMATION STORAGE AND PROCESSING Translation, ribosomal structure and biogenesis ACIAD2911 CDS +3 2846544 2846924 no panD aspartate 1-decarboxylase precursor 258 3NN4I Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine H METABOLISM Coenzyme transport and metabolism ACIAD2913 CDS +1 2847313 2847972 no ribB 3,4 dihydroxy-2-butanone-4-phosphate synthase 424 3NIMM Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate H METABOLISM Coenzyme transport and metabolism ACIAD2915 CDS -2 2848294 2848779 no conserved hypothetical protein 338 3NJGQ Protein of unknown function (DUF1289) S POORLY CHARACTERIZED Function unknown ACIAD2917 CDS +2 2849066 2850010 no conserved hypothetical protein 630 3NJY1 Belongs to the UPF0176 family S POORLY CHARACTERIZED Function unknown ACIAD2918 CDS -1 2850071 2850637 no putative acyltransferase 375 3NNP5 Acetyltransferase (GNAT) family M CELLULAR PROCESSES AND SIGNALING Cell wall/membrane/envelope biogenesis ACIAD2919 CDS +1 2850928 2851530 no putative DedA family protein 403 3NKH1 SNARE associated Golgi protein S POORLY CHARACTERIZED Function unknown ACIAD2920 CDS -1 2851532 2851972 no putative transcriptional regulator 278 3NN3J helix_turn_helix, mercury resistance K INFORMATION STORAGE AND PROCESSING Transcription ACIAD2921 CDS +1 2852038 2852520 no conserved hypothetical protein; putative membrane protein 320 3NMMD Protein of unknown function (DUF2938) S POORLY CHARACTERIZED Function unknown ACIAD2922 CDS +2 2852552 2853205 no tpm thiopurine S-methyltransferase (Thiopurine methyltransferase) (Tellurite-resistance determinant) (TEL-R determinant) 436 3NNMV response to metal ion Q METABOLISM Secondary metabolites biosynthesis, transport and catabolism ACIAD2923 CDS -3 2853363 2853887 no conserved hypothetical protein 353 3NIVS Belongs to the UPF0149 family S POORLY CHARACTERIZED Function unknown ACIAD2924 CDS -2 2853958 2854167 no atfA acidic transcription factor A 108 3NPFX S POORLY CHARACTERIZED Function unknown ACIAD2925 CDS +1 2854534 2856423 no rpoD sigma D (sigma 70) factor of RNA polymerase , major sigma factor during exponential growth 1119 3NJ78 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth K INFORMATION STORAGE AND PROCESSING Transcription ACIAD2926 CDS +1 2856517 2856816 no conserved hypothetical protein 205 3NNVP Belongs to the UPF0250 family S POORLY CHARACTERIZED Function unknown ACIAD2927 CDS +2 2856887 2857546 no lipB lipoate-protein ligase B (Lipoate biosynthesis protein B) 447 3NIWJ Catalyzes the transfer of endogenously produced octanoic acid from octanoyl-acyl-carrier-protein onto the lipoyl domains of lipoate-dependent enzymes. Lipoyl-ACP can also act as a substrate although octanoyl-ACP is likely to be the physiological substrate H METABOLISM Coenzyme transport and metabolism ACIAD2928 CDS +2 2857625 2858158 no conserved hypothetical protein 335 3NJ4B S POORLY CHARACTERIZED Function unknown ACIAD2929 CDS +1 2858161 2859345 no putative alcohol dehydrogenase 776 3NJYF Iron-containing alcohol dehydrogenase C METABOLISM Energy production and conversion ACIAD2930 CDS +3 2859579 2860991 no putative amino acid transport protein (APC family) 924 3NIMK Amino acid permease E METABOLISM Amino acid transport and metabolism ACIAD2931 CDS -1 2861039 2861614 no putative flavodoxin FldP 383 3NKG0 Flavodoxin domain S POORLY CHARACTERIZED Function unknown ACIAD2932 CDS +3 2861727 2862107 no conserved hypothetical protein; putative transcriptional regulator 251 3NNPJ HxlR-like helix-turn-helix K INFORMATION STORAGE AND PROCESSING Transcription ACIAD2933 CDS -3 2862102 2862581 no putative tRNA/rRNA methyltransferase 322 3NJB1 Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide J INFORMATION STORAGE AND PROCESSING Translation, ribosomal structure and biogenesis ACIAD2934 CDS -2 2862619 2863992 no cysG multifunctional protein [Includes: Uroporphyrin-III C-methyltransferase (Urogen III methylase) (SUMT) (Uroporphyrinogen III methylase) (UROM); Precorrin-2 oxidase ; Ferrochelatase ] (Siroheme synthase) 901 3NISX Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme H METABOLISM Coenzyme transport and metabolism ACIAD2935 CDS -1 2864057 2865334 no serS seryl-tRNA synthetase ; also charges selenocystein tRNA with serine 831 3NJIM Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec) J INFORMATION STORAGE AND PROCESSING Translation, ribosomal structure and biogenesis ACIAD2936 CDS -2 2865433 2866215 no conserved hypothetical protein 517 3NJDH Protein of unknown function (DUF3298) S POORLY CHARACTERIZED Function unknown ACIAD2937 CDS -3 2866380 2867072 no lolA outer-membrane lipoproteins carrier protein 439 3NKC7 Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane) M CELLULAR PROCESSES AND SIGNALING Cell wall/membrane/envelope biogenesis ACIAD2938 CDS -2 2867275 2867532 no rpmA 50S ribosomal protein L27 167 3NNY1 Belongs to the bacterial ribosomal protein bL27 family J INFORMATION STORAGE AND PROCESSING Translation, ribosomal structure and biogenesis ACIAD2939 CDS -2 2867551 2867862 no rplU 50S ribosomal protein L21 199 3NNGD This protein binds to 23S rRNA in the presence of protein L20 J INFORMATION STORAGE AND PROCESSING Translation, ribosomal structure and biogenesis ACIAD2940 CDS +3 2868306 2869283 no ispB octaprenyl-diphosphate synthase (Octaprenyl pyrophosphate synthetase) (OPP synthetase) 629 3NK0C Belongs to the FPP GGPP synthase family H METABOLISM Coenzyme transport and metabolism ACIAD2941 CDS +2 2869298 2871358 no conserved hypothetical protein; (putative site-specific recombinase) 1306 3NJ3G Site-specific recombinase L INFORMATION STORAGE AND PROCESSING Replication, recombination and repair ACIAD2942 CDS +3 2871510 2872127 no putative membrane-associated phospholipid phosphatase 427 3NSYD Acid phosphatase homologues I METABOLISM Lipid transport and metabolism ACIAD2943 CDS +3 2872149 2873414 no putative RND multidrug efflux membrane fusion protein MexA precursor 713 3NJZ0 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family M CELLULAR PROCESSES AND SIGNALING Cell wall/membrane/envelope biogenesis ACIAD2944 CDS +3 2873427 2876606 no putative multidrug resistance protein mexB (Multidrug-efflux transporter mexB) 1989 3NK79 efflux pump V CELLULAR PROCESSES AND SIGNALING Defense mechanisms ACIAD2945 CDS +2 2876603 2878057 no putative outer membrane protein oprM precursor 917 3NJR2 Outer membrane efflux protein M CELLULAR PROCESSES AND SIGNALING Cell wall/membrane/envelope biogenesis ACIAD2946 CDS +2 2878196 2878522 no conserved hypothetical protein 210 3NNHZ Belongs to the UPF0145 family S POORLY CHARACTERIZED Function unknown ACIAD2947 CDS +2 2878532 2878987 no conserved hypothetical protein 298 3NN5K Belongs to the UPF0145 family S POORLY CHARACTERIZED Function unknown ACIAD2948 CDS -2 2879014 2879820 no putative oxidoreductase/dehydrogenase 514 3NKHN Belongs to the short-chain dehydrogenases reductases (SDR) family S POORLY CHARACTERIZED Function unknown ACIAD2949 CDS -3 2879847 2880524 no conserved hypothetical protein 438 3NK29 S POORLY CHARACTERIZED Function unknown ACIAD2950 CDS +2 2880692 2883607 no valS valyl-tRNA synthetase 1963 3NISD amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner J INFORMATION STORAGE AND PROCESSING Translation, ribosomal structure and biogenesis ACIAD2953 CDS +2 2884139 2885026 no hypothetical protein 589 1N5T8 S POORLY CHARACTERIZED Function unknown ACIAD2955 CDS -1 2885288 2886346 no conserved hypothetical protein; putative DnaJ domain protein 635 3NJ62 DnaJ molecular chaperone homology domain O CELLULAR PROCESSES AND SIGNALING Posttranslational modification, protein turnover, chaperones ACIAD2956 CDS -1 2886401 2887306 no conserved hypothetical protein; putative membrane protein 550 3NJRQ Membrane transport protein S POORLY CHARACTERIZED Function unknown ACIAD2958 CDS +2 2887667 2888884 no putative ammonium transporter 784 3NJD0 Ammonium Transporter Family P METABOLISM Inorganic ion transport and metabolism ACIAD2959 CDS +1 2888947 2889696 no conserved hypothetical protein 518 3NITS PAP2 superfamily S POORLY CHARACTERIZED Function unknown ACIAD2960 CDS -2 2889832 2891157 no qseC two-component sensor kinase transcription regulator protein 846 3NJX0 His Kinase A (phosphoacceptor) domain T CELLULAR PROCESSES AND SIGNALING Signal transduction mechanisms ACIAD2961 CDS -3 2891169 2891849 no qseB transcriptional regulator 442 3NIVZ Transcriptional regulatory protein, C terminal K INFORMATION STORAGE AND PROCESSING Transcription ACIAD2961 CDS -3 2891169 2891849 no qseB transcriptional regulator 442 3NIVZ Transcriptional regulatory protein, C terminal T CELLULAR PROCESSES AND SIGNALING Signal transduction mechanisms ACIAD2963 CDS -1 2892263 2893510 no putative transporter (MFS superfamily) 780 3NJ30 Acetyl-coenzyme A transporter 1 E METABOLISM Amino acid transport and metabolism ACIAD2963 CDS -1 2892263 2893510 no putative transporter (MFS superfamily) 780 3NJ30 Acetyl-coenzyme A transporter 1 G METABOLISM Carbohydrate transport and metabolism ACIAD2963 CDS -1 2892263 2893510 no putative transporter (MFS superfamily) 780 3NJ30 Acetyl-coenzyme A transporter 1 P METABOLISM Inorganic ion transport and metabolism ACIAD2964 CDS +3 2893620 2894270 no conserved hypothetical protein; putative acyltransferase 449 3NK72 Phosphate acyltransferases I METABOLISM Lipid transport and metabolism ACIAD2965 CDS +2 2894336 2895253 no conserved hypothetical protein; putative esterase 580 3NKS7 Patatin-like phospholipase S POORLY CHARACTERIZED Function unknown ACIAD2966 CDS +1 2895352 2895822 no conserved hypothetical protein; putative membrane protein 305 3NJ6H COG1585 Membrane protein implicated in regulation of membrane protease activity O CELLULAR PROCESSES AND SIGNALING Posttranslational modification, protein turnover, chaperones ACIAD2966 CDS +1 2895352 2895822 no conserved hypothetical protein; putative membrane protein 305 3NJ6H COG1585 Membrane protein implicated in regulation of membrane protease activity U CELLULAR PROCESSES AND SIGNALING Intracellular trafficking, secretion, and vesicular transport ACIAD2967 CDS +1 2895832 2896689 no conserved hypothetical protein; putative membrane protease subunit 480 3NK06 prohibitin homologues O CELLULAR PROCESSES AND SIGNALING Posttranslational modification, protein turnover, chaperones ACIAD2968 CDS -2 2896765 2897673 no ispA geranyltranstransferase (farnesyldiphosphate synthase) (FPP synthase) 580 3NK6Z Belongs to the FPP GGPP synthase family H METABOLISM Coenzyme transport and metabolism ACIAD2969 CDS +2 2898161 2899519 no aroP aromatic amino acid transporter (APC family) 877 3NJKE Amino acid permease E METABOLISM Amino acid transport and metabolism ACIAD2971 CDS +3 2899827 2899988 no conserved hypothetical protein 114 3NQH6 Uncharacterized protein conserved in bacteria (DUF2256) S POORLY CHARACTERIZED Function unknown ACIAD2972 CDS -3 2899998 2900303 no conserved hypothetical protein 197 3NPC6 Protein of unknown function (DUF2805) S POORLY CHARACTERIZED Function unknown ACIAD2973 CDS -1 2900378 2901091 no kdpE regulator of kdp operon (transcriptional effector) 465 3NKT4 Transcriptional regulatory protein, C terminal K INFORMATION STORAGE AND PROCESSING Transcription ACIAD2973 CDS -1 2900378 2901091 no kdpE regulator of kdp operon (transcriptional effector) 465 3NKT4 Transcriptional regulatory protein, C terminal T CELLULAR PROCESSES AND SIGNALING Signal transduction mechanisms ACIAD2975 CDS -1 2901101 2903746 no kdpD sensory kinase in two-component regulatory system wtih KdpE, regulates high-affinity potassium transport system 1684 3NJUN Domain of unknown function (DUF4118) T CELLULAR PROCESSES AND SIGNALING Signal transduction mechanisms ACIAD2976 CDS -3 2903754 2904383 no kdpC potassium-transporting ATPase C chain 386 3NJ74 Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit acts as a catalytic chaperone that increases the ATP- binding affinity of the ATP-hydrolyzing subunit KdpB by the formation of a transient KdpB KdpC ATP ternary complex P METABOLISM Inorganic ion transport and metabolism ACIAD2977 CDS -3 2904393 2906408 no kdpB potassium-transporting ATPase B chain 1223 3NITI Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit is responsible for energy coupling to the transport system P METABOLISM Inorganic ion transport and metabolism ACIAD2978 CDS -2 2906425 2908134 no kdpA potassium-transporting ATPase A chain 1090 3NJUU Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit binds and transports the potassium across the cytoplasmic membrane P METABOLISM Inorganic ion transport and metabolism ACIAD2979 CDS -2 2908333 2908785 no putative transcriptional regulator (AsnC family) 286 3NK0U AsnC-type helix-turn-helix domain K INFORMATION STORAGE AND PROCESSING Transcription ACIAD2980 CDS +3 2908938 2909552 no conserved hypothetical protein; putative amino acid efflux transmembrane protein 381 3NM4B LysE type translocator E METABOLISM Amino acid transport and metabolism ACIAD2981 CDS -3 2909670 2910188 no putative oxidoreductase involved in sulfite reduction 338 3NIPY Bacterial protein of unknown function (DUF934) S POORLY CHARACTERIZED Function unknown ACIAD2982 CDS -2 2910148 2911791 no cysI Sulfite reductase (NADPH) hemoprotein beta-component 1093 3NKEQ Belongs to the nitrite and sulfite reductase 4Fe-4S domain family C METABOLISM Energy production and conversion ACIAD2983 CDS -1 2911967 2914372 no gcd glucose dehydrogenase [pyrroloquinoline-quinone] precursor (Quinoprotein glucose DH) 1633 3NJDR PQQ-like domain G METABOLISM Carbohydrate transport and metabolism ACIAD2984 CDS -1 2914520 2915770 no putative glucose-sensitive porin (OprB-like ) 857 3NJ0T Carbohydrate-selective porin, OprB family M CELLULAR PROCESSES AND SIGNALING Cell wall/membrane/envelope biogenesis ACIAD2985 CDS -1 2915918 2917036 no putative acyl-CoA transferase 741 3NJIN CoA-transferase family III C METABOLISM Energy production and conversion ACIAD2986 CDS +1 2917210 2918256 no putative transcriptional regulator (AraC family) (AdiY) 697 3NJS4 Arabinose-binding domain of AraC transcription regulator, N-term K INFORMATION STORAGE AND PROCESSING Transcription ACIAD2987 CDS -2 2918308 2918841 no conserved hypothetical protein; putative kinase 366 3NMM7 AAA domain F METABOLISM Nucleotide transport and metabolism ACIAD2988 CDS +3 2919024 2920232 no putative thiolase; putative acyl-CoA thiolase 774 3NJER Belongs to the thiolase family I METABOLISM Lipid transport and metabolism ACIAD2989 CDS +1 2920243 2922378 no putative 3-hydroxybutyryl-CoA epimerase 1378 3NJ99 Belongs to the enoyl-CoA hydratase isomerase family I METABOLISM Lipid transport and metabolism ACIAD2990 CDS +3 2922519 2922767 no hypothetical protein 155 3NPCZ S POORLY CHARACTERIZED Function unknown ACIAD2991 CDS +3 2922783 2923640 no conserved hypothetical protein; putative esterase 577 3NKPW Patatin-like phospholipase S POORLY CHARACTERIZED Function unknown ACIAD2992 CDS -3 2923665 2924090 no conserved hypothetical protein 295 3NNHY Glyoxalase-like domain E METABOLISM Amino acid transport and metabolism ACIAD2993 CDS -1 2924045 2924695 no conserved hypothetical protein; putative signal peptide 458 3NMXQ S POORLY CHARACTERIZED Function unknown ACIAD2994 CDS -2 2924785 2925240 no putative acetyl transferase 300 3NP13 Acetyltransferase (GNAT) domain S POORLY CHARACTERIZED Function unknown ACIAD2995 CDS -3 2925258 2926481 no putative methyltransferase 799 3NJCM Methyltransferase domain J INFORMATION STORAGE AND PROCESSING Translation, ribosomal structure and biogenesis ACIAD2996 CDS +1 2926501 2927226 no putative hemolysin III (HLY-III) 471 3NJXT Haemolysin-III related S POORLY CHARACTERIZED Function unknown ACIAD2997 CDS +1 2927368 2928678 no putative transport protein (MFS superfamily) 825 3NIYY Sugar (and other) transporter E METABOLISM Amino acid transport and metabolism ACIAD2997 CDS +1 2927368 2928678 no putative transport protein (MFS superfamily) 825 3NIYY Sugar (and other) transporter G METABOLISM Carbohydrate transport and metabolism ACIAD2997 CDS +1 2927368 2928678 no putative transport protein (MFS superfamily) 825 3NIYY Sugar (and other) transporter P METABOLISM Inorganic ion transport and metabolism ACIAD2999 CDS +3 2928792 2929574 no conserved hypothetical protein 512 3NPVS ribosome binding J INFORMATION STORAGE AND PROCESSING Translation, ribosomal structure and biogenesis ACIAD3000 CDS -3 2929593 2930615 no conserved hypothetical protein; putative membrane protein 687 3NJX4 Calcineurin-like phosphoesterase superfamily domain S POORLY CHARACTERIZED Function unknown ACIAD3001 CDS +1 2930785 2932344 no putative phospholipase D protein 1025 3NK7J Phospholipase D I METABOLISM Lipid transport and metabolism ACIAD3002 CDS -1 2932337 2933152 no plsC2 1-acylglycerol-3-phosphate O-acyltransferase 540 3NK5N Acyltransferase I METABOLISM Lipid transport and metabolism ACIAD3005 CDS +2 2933543 2934877 no hflX GTP-binding protein 841 3NJV9 GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis S POORLY CHARACTERIZED Function unknown ACIAD3006 CDS +1 2934922 2935293 no conserved hypothetical protein 251 3NNKR Effector of murein hydrolase LrgA S POORLY CHARACTERIZED Function unknown ACIAD3007 CDS +2 2935307 2935975 no conserved hypothetical protein; putative membrane protein 412 3NIKB LrgB-like family M CELLULAR PROCESSES AND SIGNALING Cell wall/membrane/envelope biogenesis ACIAD3008 CDS -2 2936032 2936883 no apaH bis(5'-nucleosyl)-tetraphosphatase, symmetrical (Diadenosine tetraphosphatase) (Ap4A hydrolase) (Diadenosine 5',5'''- P1,P4-tetraphosphate pyrophosphohydrolase) 590 3NKGH Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP T CELLULAR PROCESSES AND SIGNALING Signal transduction mechanisms ACIAD3009 CDS -3 2936886 2937710 no ksgA S-adenosylmethionine-6-N',N'-adenosyl (rRNA) dimethyltransferase, kasugamycin resistance 545 3NK8E Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits J INFORMATION STORAGE AND PROCESSING Translation, ribosomal structure and biogenesis ACIAD3010 CDS -2 2937721 2938689 no pdxA 4-hydroxythreonine-4-phosphate dehydrogenase (4- (phosphohydroxy)-L-threonine dehydrogenase) 622 3NIRN Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP) H METABOLISM Coenzyme transport and metabolism ACIAD3012 CDS +2 2938994 2939422 no rplM 50S ribosomal protein L13 292 3NJCQ This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly J INFORMATION STORAGE AND PROCESSING Translation, ribosomal structure and biogenesis ACIAD3013 CDS +2 2939435 2939821 no rpsI 30S ribosomal protein S9 241 3NN52 Belongs to the universal ribosomal protein uS9 family J INFORMATION STORAGE AND PROCESSING Translation, ribosomal structure and biogenesis ACIAD3014 CDS +2 2940050 2940700 no sspA stringent starvation protein A 432 3NIP4 starvation protein A O CELLULAR PROCESSES AND SIGNALING Posttranslational modification, protein turnover, chaperones ACIAD3015 CDS +1 2940712 2941146 no sspB stringent starvation protein B 293 3NN7X stringent starvation protein B S POORLY CHARACTERIZED Function unknown ACIAD3016 CDS +1 2941165 2941833 no conserved hypothetical protein 436 3NIU9 S POORLY CHARACTERIZED Function unknown ACIAD3018 CDS +3 2947926 2948852 no putative lipoprotein precursor (VacJ) transmembrane 592 3NK9B MlaA lipoprotein M CELLULAR PROCESSES AND SIGNALING Cell wall/membrane/envelope biogenesis ACIAD3019 CDS +3 2948985 2949953 no putative two-component response regulator 661 3NJ5N Sigma factor PP2C-like phosphatases K INFORMATION STORAGE AND PROCESSING Transcription ACIAD3019 CDS +3 2948985 2949953 no putative two-component response regulator 661 3NJ5N Sigma factor PP2C-like phosphatases T CELLULAR PROCESSES AND SIGNALING Signal transduction mechanisms ACIAD3020 CDS +2 2950007 2950588 no conserved hypothetical protein; putative anti-anti-sigma factor 375 3NKKC COG1366 Anti-anti-sigma regulatory factor (antagonist of anti-sigma factor) T CELLULAR PROCESSES AND SIGNALING Signal transduction mechanisms ACIAD3021 CDS +2 2950613 2951437 no putative carbon-nitrogen hydrolase 550 3NIXM Carbon-nitrogen hydrolase S POORLY CHARACTERIZED Function unknown ACIAD3022 CDS +1 2951503 2951964 no putative organic hydroperoxide resistance transcriptional regulator (ohrR) 287 3NJX8 helix_turn_helix multiple antibiotic resistance protein K INFORMATION STORAGE AND PROCESSING Transcription ACIAD3023 CDS +1 2952049 2952480 no ohr organic hydroperoxide resistance protein 295 3NM8J OsmC-like protein O CELLULAR PROCESSES AND SIGNALING Posttranslational modification, protein turnover, chaperones ACIAD3024 CDS -3 2952534 2954024 no xcpR general secretion pathway protein E (Type II traffic warden ATPase) 960 3NIQS Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB N CELLULAR PROCESSES AND SIGNALING Cell motility ACIAD3024 CDS -3 2952534 2954024 no xcpR general secretion pathway protein E (Type II traffic warden ATPase) 960 3NIQS Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB U CELLULAR PROCESSES AND SIGNALING Intracellular trafficking, secretion, and vesicular transport ACIAD3025 CDS +1 2954122 2954943 no conserved hypothetical protein 578 3NIUC S POORLY CHARACTERIZED Function unknown ACIAD3026 CDS +3 2954952 2955872 no putative small conductance mechanosensitive ion channel 579 3NIPP Mechanosensitive ion channel M CELLULAR PROCESSES AND SIGNALING Cell wall/membrane/envelope biogenesis ACIAD3028 CDS -2 2956060 2958969 no conserved hypothetical protein; putative membrane protein 1758 3NJ9V Predicted membrane protein (DUF2339) S POORLY CHARACTERIZED Function unknown ACIAD3030 CDS +2 2959118 2961880 no polA DNA polymerase I, 3' --> 5' polymerase, 5' --> 3' and 3'--> 5' exonuclease 1793 3NK2H In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity L INFORMATION STORAGE AND PROCESSING Replication, recombination and repair ACIAD3031 CDS -2 2961931 2962497 no conserved hypothetical protein; putative integral membrane resistance protein 334 3NKEM YGGT family S POORLY CHARACTERIZED Function unknown ACIAD3032 CDS -1 2962514 2963350 no proC pyrroline-5-carboxylate reductase 506 3NJW4 Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline E METABOLISM Amino acid transport and metabolism ACIAD3034 CDS -2 2963347 2964726 no tilS tRNA(Ile)-lysidine synthetase 867 3NKUQ Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine D CELLULAR PROCESSES AND SIGNALING Cell cycle control, cell division, chromosome partitioning ACIAD3035 CDS -3 2964663 2965487 no accA acetyl-coenzyme A carboxylase carboxyl transferase (alpha subunit) 539 3NK3T Component of the acetyl coenzyme A carboxylase (ACC) complex. First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-CoA I METABOLISM Lipid transport and metabolism ACIAD3036 CDS -1 2965523 2967043 no ppx exopolyphosphatase (ExopolyPase) (Metaphosphatase) 979 3NIV4 Belongs to the GppA Ppx family F METABOLISM Nucleotide transport and metabolism ACIAD3036 CDS -1 2965523 2967043 no ppx exopolyphosphatase (ExopolyPase) (Metaphosphatase) 979 3NIV4 Belongs to the GppA Ppx family P METABOLISM Inorganic ion transport and metabolism ACIAD3037 CDS +3 2967309 2967647 no trxA thioredoxin 225 3NNP2 Belongs to the thioredoxin family O CELLULAR PROCESSES AND SIGNALING Posttranslational modification, protein turnover, chaperones ACIAD3038 CDS +1 2967985 2969253 no rho transcription termination factor 813 3NJ6D Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template K INFORMATION STORAGE AND PROCESSING Transcription ACIAD3039 CDS +2 2969669 2969935 no conserved hypothetical protein; putative signal peptide 62.4 3NPVQ S POORLY CHARACTERIZED Function unknown ACIAD3040 CDS -1 2970092 2970385 no himA integration host factor (IHF), alpha subunit, DNA-binding protein, DNA replication 189 3NNXR This protein is one of the two subunits of integration host factor, a specific DNA-binding protein that functions in genetic recombination as well as in transcriptional and translational control K INFORMATION STORAGE AND PROCESSING Transcription ACIAD3041 CDS -2 2970382 2972763 no pheT phenylalanyl-tRNA synthetase, beta subunit 1550 3NK31 Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily J INFORMATION STORAGE AND PROCESSING Translation, ribosomal structure and biogenesis ACIAD3042 CDS -1 2972798 2973790 no pheS phenylalanyl-tRNA synthetase, alpha-subunit 649 3NJCI Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily J INFORMATION STORAGE AND PROCESSING Translation, ribosomal structure and biogenesis ACIAD3043 CDS +3 2973918 2974973 no conserved hypothetical protein 680 3NKGU S POORLY CHARACTERIZED Function unknown ACIAD3044 CDS -3 2975025 2975222 no conserved hypothetical protein 132 3NPAN S POORLY CHARACTERIZED Function unknown ACIAD3045 CDS -3 2975274 2975471 no hypothetical protein 49.7 3NM8Y Domain of unknown function (DUF1768) O CELLULAR PROCESSES AND SIGNALING Posttranslational modification, protein turnover, chaperones ACIAD3046 CDS -3 2975691 2976050 no rplT 50S ribosomal protein L20, also posttranslational autoregulator 219 3NNG8 Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit J INFORMATION STORAGE AND PROCESSING Translation, ribosomal structure and biogenesis ACIAD3047 CDS -1 2976062 2976256 no rpmI 50S ribosomal protein L35 124 3NPCF Belongs to the bacterial ribosomal protein bL35 family J INFORMATION STORAGE AND PROCESSING Translation, ribosomal structure and biogenesis ACIAD3048 CDS +1 2976484 2977746 no putative transporter 822 3NJMG Transmembrane secretion effector E METABOLISM Amino acid transport and metabolism ACIAD3048 CDS +1 2976484 2977746 no putative transporter 822 3NJMG Transmembrane secretion effector G METABOLISM Carbohydrate transport and metabolism ACIAD3048 CDS +1 2976484 2977746 no putative transporter 822 3NJMG Transmembrane secretion effector P METABOLISM Inorganic ion transport and metabolism ACIAD3049 CDS +3 2977863 2978567 no putative TonB_C domain-containing protein 454 3NMVT Interacts with outer membrane receptor proteins that carry out high-affinity binding and energy dependent uptake into the periplasmic space of specific substrates. It could act to transduce energy from the cytoplasmic membrane to specific energy- requiring processes in the outer membrane, resulting in the release into the periplasm of ligands bound by these outer membrane proteins M CELLULAR PROCESSES AND SIGNALING Cell wall/membrane/envelope biogenesis ACIAD3050 CDS -3 2978610 2979038 no conserved hypothetical protein; putative membrane protein 275 3NNNH SNARE associated Golgi protein S POORLY CHARACTERIZED Function unknown ACIAD3051 CDS -3 2979141 2979761 no putative glutathione S-transferase 431 3NIXR Belongs to the GST superfamily O CELLULAR PROCESSES AND SIGNALING Posttranslational modification, protein turnover, chaperones ACIAD3053 CDS +1 2980033 2980527 no ibp small heat-shock protein 315 3NNJV Belongs to the small heat shock protein (HSP20) family O CELLULAR PROCESSES AND SIGNALING Posttranslational modification, protein turnover, chaperones ACIAD3054 CDS -2 2980636 2981187 no infC protein chain initiation factor IF-3 339 3NISA IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins J INFORMATION STORAGE AND PROCESSING Translation, ribosomal structure and biogenesis ACIAD3055 CDS -3 2981193 2983115 no thrS threonyl-tRNA synthetase 1306 3NIJ5 Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr) J INFORMATION STORAGE AND PROCESSING Translation, ribosomal structure and biogenesis ACIAD3056 CDS +1 2983528 2985171 no putative AMP-dependent synthetase/ligase 1118 3NJHU AMP-binding enzyme C-terminal domain I METABOLISM Lipid transport and metabolism ACIAD3056 CDS +1 2983528 2985171 no putative AMP-dependent synthetase/ligase 1118 3NJHU AMP-binding enzyme C-terminal domain Q METABOLISM Secondary metabolites biosynthesis, transport and catabolism ACIAD3057 CDS -2 2985256 2985789 no conserved hypothetical protein 332 3NISC Belongs to the UPF0307 family S POORLY CHARACTERIZED Function unknown ACIAD3058 CDS -3 2985792 2986067 no ptsO phosphocarrier protein (HPr-like) NPr, nitrogen related, exchanges phosphate with Enzyme I 172 3NNXF PTS HPr component phosphorylation site G METABOLISM Carbohydrate transport and metabolism ACIAD3059 CDS -1 2986058 2986909 no conserved hypothetical protein 577 3NIN4 Displays ATPase and GTPase activities S POORLY CHARACTERIZED Function unknown ACIAD3060 CDS -1 2986931 2987776 no panC pantoate--beta-alanine ligase (Pantothenate synthetase) (Pantoate activating enzyme) 554 3NJJJ Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate H METABOLISM Coenzyme transport and metabolism ACIAD3061 CDS -1 2987780 2988532 no panB 3-methyl-2-oxobutanoate hydroxymethyltransferase (Ketopantoate hydroxymethyltransferase) 490 3NIP8 Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is transferred onto alpha-ketoisovalerate to form ketopantoate H METABOLISM Coenzyme transport and metabolism ACIAD3062 CDS -3 2988627 2989115 no folK 2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase (7,8-dihydro-6-hydroxymethylpterin-pyrophosphokinase) (HPPK) (6-hydroxymethyl-7,8-dihydropterin pyrophosphokinase) (PPPK) 320 3NNAE 7,8-dihydro-6-hydroxymethylpterin-pyrophosphokinase (HPPK) H METABOLISM Coenzyme transport and metabolism ACIAD3063 CDS -1 2989112 2990569 no pcnB poly(A) polymerase I (PAP) 948 3NJ8X Adds poly(A) tail to the 3' end of many RNAs, which usually targets these RNAs for decay. Plays a significant role in the global control of gene expression, through influencing the rate of transcript degradation, and in the general RNA quality control J INFORMATION STORAGE AND PROCESSING Translation, ribosomal structure and biogenesis ACIAD3064 CDS -3 2990694 2991080 no putative DNA uptake protein and/or related DNA-binding protein 248 3NPCU Helix-hairpin-helix motif L INFORMATION STORAGE AND PROCESSING Replication, recombination and repair ACIAD3065 CDS -3 2991084 2991851 no putative nucleoside triphosphate pyrophosphohydrolase (MazG) 488 3NJ40 Nucleoside triphosphate pyrophosphohydrolase S POORLY CHARACTERIZED Function unknown ACIAD3067 CDS +2 2991965 2992747 no putative short-chain dehydrogenase 509 3NKIG Belongs to the short-chain dehydrogenases reductases (SDR) family I METABOLISM Lipid transport and metabolism ACIAD3067 CDS +2 2991965 2992747 no putative short-chain dehydrogenase 509 3NKIG Belongs to the short-chain dehydrogenases reductases (SDR) family Q METABOLISM Secondary metabolites biosynthesis, transport and catabolism ACIAD3068 CDS -3 2992794 2995100 no relA GTP pyrophosphokinase (ATP:GTP 3'-pyrophosphotransferase) (ppGpp synthetase I) ((p)ppGpp synthetase) 1484 3NJ4S In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance K INFORMATION STORAGE AND PROCESSING Transcription ACIAD3068 CDS -3 2992794 2995100 no relA GTP pyrophosphokinase (ATP:GTP 3'-pyrophosphotransferase) (ppGpp synthetase I) ((p)ppGpp synthetase) 1484 3NJ4S In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance T CELLULAR PROCESSES AND SIGNALING Signal transduction mechanisms ACIAD3069 CDS -1 2995133 2996524 no rumA 23S rRNA (Uracil-5-)-methyltransferase(23S rRNA(M- 5-U1939)-methyltransferase) 932 3NJ5F Catalyzes the formation of 5-methyl-uridine at position 1939 (m5U1939) in 23S rRNA J INFORMATION STORAGE AND PROCESSING Translation, ribosomal structure and biogenesis ACIAD3070 CDS -2 2996521 2997357 no conserved hypothetical protein 574 3NINT 3'-5' exonuclease related to the exonuclease domain of PolB L INFORMATION STORAGE AND PROCESSING Replication, recombination and repair ACIAD3071 CDS -3 2997387 2998310 no cysM cysteine synthase B (O-acetylserine sulfhydrolase B) 612 3NJVZ Belongs to the cysteine synthase cystathionine beta- synthase family E METABOLISM Amino acid transport and metabolism ACIAD3072 CDS +2 2998466 3001264 no barA GacS-like sensor kinase protein 1779 3NJVK Histidine kinase T CELLULAR PROCESSES AND SIGNALING Signal transduction mechanisms ACIAD3073 CDS +1 3001345 3002133 no putative enoyl-CoA hydratase/isomerase 511 3NT3T Enoyl-CoA hydratase/isomerase I METABOLISM Lipid transport and metabolism ACIAD3074 CDS +3 3002148 3003023 no glxR 2-hydroxy-3-oxopropionate reductase 561 3NJ3X NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase I METABOLISM Lipid transport and metabolism ACIAD3075 CDS +3 3003039 3003836 no hyi hydroxypyruvate isomerase 531 3NISK Belongs to the hyi family G METABOLISM Carbohydrate transport and metabolism ACIAD3076 CDS +3 3004005 3004358 no conserved hypothetical protein 234 3NN48 Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation J INFORMATION STORAGE AND PROCESSING Translation, ribosomal structure and biogenesis ACIAD3077 CDS -1 3004463 3004831 no hypothetical protein; putative membrane protein 240 3NQIM S POORLY CHARACTERIZED Function unknown ACIAD3078 CDS -3 3004854 3006308 no pntB pyridine nucleotide transhydrogenase, beta subunit 934 3NJ3M The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane C METABOLISM Energy production and conversion ACIAD3079 CDS -3 3006321 3006635 no pntA-2 pyridine nucleotide transhydrogenase (proton pump), alpha subunit (part2) 191 3NNJ0 4TM region of pyridine nucleotide transhydrogenase, mitoch C METABOLISM Energy production and conversion ACIAD3080 CDS -1 3006647 3007774 no pntA-1 pyridine nucleotide transhydrogenase (proton pump), alpha subunit (part1) 714 3NJZX Alanine dehydrogenase/PNT, N-terminal domain C METABOLISM Energy production and conversion ACIAD3081 CDS +2 3007958 3008935 no putative membrane protein 623 3NKS2 EamA-like transporter family E METABOLISM Amino acid transport and metabolism ACIAD3081 CDS +2 3007958 3008935 no putative membrane protein 623 3NKS2 EamA-like transporter family G METABOLISM Carbohydrate transport and metabolism ACIAD3082 CDS -2 3008932 3009426 no soxR transcriptional activator for superoxide response, contains iron-sulfur center for redox-sensing (MerR family) 325 3NMGS helix_turn_helix, mercury resistance K INFORMATION STORAGE AND PROCESSING Transcription ACIAD3083 CDS +3 3009447 3009911 no conserved hypothetical protein 310 3NTA6 Endoribonuclease L-PSP J INFORMATION STORAGE AND PROCESSING Translation, ribosomal structure and biogenesis ACIAD3084 CDS +2 3009926 3011122 no putative transport protein (MFS superfamily) 724 3NJ19 Major Facilitator Superfamily E METABOLISM Amino acid transport and metabolism ACIAD3084 CDS +2 3009926 3011122 no putative transport protein (MFS superfamily) 724 3NJ19 Major Facilitator Superfamily G METABOLISM Carbohydrate transport and metabolism ACIAD3084 CDS +2 3009926 3011122 no putative transport protein (MFS superfamily) 724 3NJ19 Major Facilitator Superfamily P METABOLISM Inorganic ion transport and metabolism ACIAD3085 CDS +3 3011196 3012221 no dusA tRNA-dihydrouridine synthase A 701 3NKCC Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines. Specifically modifies U20 and U20a in tRNAs J INFORMATION STORAGE AND PROCESSING Translation, ribosomal structure and biogenesis ACIAD3087 CDS +1 3012538 3013017 no conserved hypothetical protein 321 3NMK0 COG3209 Rhs family protein M CELLULAR PROCESSES AND SIGNALING Cell wall/membrane/envelope biogenesis ACIAD3088 CDS -3 3013044 3013817 no putative tRNA threonylcarbamoyladenosine dehydratase (tcdA) 505 3NIH2 COG1179 Dinucleotide-utilizing enzymes involved in molybdopterin and thiamine biosynthesis family 1 H METABOLISM Coenzyme transport and metabolism ACIAD3089 CDS -2 3013912 3014403 no ridA imine deaminase 318 3NR9Y YjgF/chorismate_mutase-like, putative endoribonuclease J INFORMATION STORAGE AND PROCESSING Translation, ribosomal structure and biogenesis ACIAD3090 CDS -1 3014513 3017266 no acnA aconitate hydratase 1 1825 3NKPZ Catalyzes the isomerization of citrate to isocitrate via cis-aconitate C METABOLISM Energy production and conversion ACIAD3091 CDS -2 3017386 3018204 no putative DNase 544 3NK6P TatD related DNase L INFORMATION STORAGE AND PROCESSING Replication, recombination and repair ACIAD3092 CDS -2 3018208 3019146 no conserved hypothetical protein; putative conserved domain 597 3NJQ6 Protein of unknown function (DUF3298) S POORLY CHARACTERIZED Function unknown ACIAD3093 CDS -2 3019234 3020052 no conserved hypothetical protein 541 3NIW3 S POORLY CHARACTERIZED Function unknown ACIAD3095 CDS -2 3020131 3021720 no prfC peptide chain release factor 3 1070 3NJ7Y Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP J INFORMATION STORAGE AND PROCESSING Translation, ribosomal structure and biogenesis ACIAD3099 CDS -1 3022178 3024223 no putative signaling protein 1316 3NIQ1 Putative diguanylate phosphodiesterase T CELLULAR PROCESSES AND SIGNALING Signal transduction mechanisms ACIAD3102 CDS -3 3024495 3025511 no ilvC acetohydroxy acid isomeroreductase and 2-dehydropantoate 2-reductase 665 3NIUP Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate H METABOLISM Coenzyme transport and metabolism ACIAD3103 CDS -1 3025544 3026035 no ilvH acetolactate synthase isozyme III, small subunit 306 3NK7Y Acetolactate synthase small E METABOLISM Amino acid transport and metabolism ACIAD3104 CDS -2 3026035 3027759 no ilvI acetolactate synthase III, large subunit 1153 3NJ1B acetolactate synthase H METABOLISM Coenzyme transport and metabolism ACIAD3105 CDS +1 3028348 3028677 no conserved hypothetical protein; putative signal peptide 211 3NPVU Domain of unknown function (DUF4124) S POORLY CHARACTERIZED Function unknown ACIAD3106 CDS +3 3028827 3031448 no leuS leucyl-tRNA synthetase 1762 3NJJI Belongs to the class-I aminoacyl-tRNA synthetase family J INFORMATION STORAGE AND PROCESSING Translation, ribosomal structure and biogenesis ACIAD3107 CDS +3 3031476 3031991 no putative minor lipoprotein 330 3NKK6 Together with LptD, is involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane. Required for the proper assembly of LptD. Binds LPS and may serve as the LPS recognition site at the outer membrane M CELLULAR PROCESSES AND SIGNALING Cell wall/membrane/envelope biogenesis ACIAD3108 CDS +1 3032008 3033003 no putative DNA polymerase III, delta subunit (probably ATP hydrolase) (HolA) 657 3NJD1 DNA polymerase III, delta subunit L INFORMATION STORAGE AND PROCESSING Replication, recombination and repair ACIAD3109 CDS +2 3033104 3034456 no putative secretion protein (HlyD family) 701 3NJBY Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family M CELLULAR PROCESSES AND SIGNALING Cell wall/membrane/envelope biogenesis ACIAD3110 CDS +1 3034456 3036450 no macB macrolide transport protein (ABC superfamily, atp_bind (N-terminal), membrane (C-terminal)) 1228 3NM2I Part of the tripartite efflux system MacAB-TolC. MacB is a non-canonical ABC transporter that contains transmembrane domains (TMD), which form a pore in the inner membrane, and an ATP-binding domain (NBD), which is responsible for energy generation. Confers resistance against macrolides V CELLULAR PROCESSES AND SIGNALING Defense mechanisms ACIAD3111 CDS +3 3036462 3037856 no putative outer membrane protein precursor 821 3NIGG Outer membrane efflux protein M CELLULAR PROCESSES AND SIGNALING Cell wall/membrane/envelope biogenesis ACIAD3112 CDS +2 3038267 3039250 no putative sulfatase-modifying factor enzyme 675 3NJIE Sulfatase-modifying factor enzyme 1 S POORLY CHARACTERIZED Function unknown ACIAD3113 CDS +2 3039389 3040372 no putative sulfatase-modifying factor enzyme 666 3NJIE Sulfatase-modifying factor enzyme 1 S POORLY CHARACTERIZED Function unknown ACIAD3114 CDS -3 3040392 3043397 no conserved hypothetical protein 1912 3NMTU chlorophyll binding M CELLULAR PROCESSES AND SIGNALING Cell wall/membrane/envelope biogenesis ACIAD3115 CDS -3 3043404 3046166 no putative VGR-related protein 1703 3NIE7 Phage late control gene D protein (GPD) S POORLY CHARACTERIZED Function unknown ACIAD3116 CDS -3 3046323 3047198 no fabI NADH-dependent enoyl-ACP reductase 571 3NJ06 Enoyl- acyl-carrier-protein reductase NADH I METABOLISM Lipid transport and metabolism ACIAD3117 CDS -1 3047270 3048001 no conserved hypothetical protein; putative membrane protein 446 3NIZK Bax inhibitor 1 like S POORLY CHARACTERIZED Function unknown ACIAD3118 CDS -2 3048223 3048774 no orn oligoribonuclease 369 3NIIC 3'-to-5' exoribonuclease specific for small oligoribonucleotides A INFORMATION STORAGE AND PROCESSING RNA processing and modification ACIAD3119 CDS +3 3048897 3049955 no putative ribosome biogenesis GTPase RsgA 670 3NIP6 One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Helps release RbfA from mature subunits. May play a role in the assembly of ribosomal proteins into the subunit. Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit S POORLY CHARACTERIZED Function unknown ACIAD3120 CDS +1 3050026 3050463 no putative rhodanese-related sulfurtransferase 291 3NN3Y Rhodanese Homology Domain P METABOLISM Inorganic ion transport and metabolism ACIAD3121 CDS +1 3050476 3050733 no grx glutaredoxin 172 3NNVE Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins O CELLULAR PROCESSES AND SIGNALING Posttranslational modification, protein turnover, chaperones ACIAD3122 CDS +3 3050763 3051218 no secB molecular chaperone in protein export 298 3NK4T One of the proteins required for the normal export of preproteins out of the cell cytoplasm. It is a molecular chaperone that binds to a subset of precursor proteins, maintaining them in a translocation-competent state. It also specifically binds to its receptor SecA U CELLULAR PROCESSES AND SIGNALING Intracellular trafficking, secretion, and vesicular transport ACIAD3123 CDS -1 3051278 3051691 no putative precursor of Cytochrome b(562) (CybC) 246 3NT8Z Cytochrome b562 P METABOLISM Inorganic ion transport and metabolism ACIAD3125 CDS -3 3051780 3053060 no dfp bifunctional protein [Includes: 4'-phosphopantothenoylcysteine decarboxylase; phosphopantothenoylcysteine synthetase, FMN-binding] 819 3NJ8G Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine H METABOLISM Coenzyme transport and metabolism ACIAD3126 CDS +2 3053102 3053917 no radC DNA repair protein, associated with replication forks 547 3NJ7R Belongs to the UPF0758 family E METABOLISM Amino acid transport and metabolism ACIAD3127 CDS +1 3053914 3054825 no conserved hypothetical protein; putative membrane protein 601 3NIGF Bestrophin, RFP-TM, chloride channel S POORLY CHARACTERIZED Function unknown ACIAD3128 CDS -3 3054846 3055904 no putative oxidoreductase 687 3NT27 Aldo/keto reductase family C METABOLISM Energy production and conversion ACIAD3129 CDS +2 3055982 3056911 no putative transcriptional regulator (LysR family) 615 3NT56 LysR substrate binding domain K INFORMATION STORAGE AND PROCESSING Transcription ACIAD3130 CDS +3 3057063 3057686 no putative glutathione S-transferase 440 3NIJH Glutathione S-transferase, N-terminal domain O CELLULAR PROCESSES AND SIGNALING Posttranslational modification, protein turnover, chaperones ACIAD3131 CDS -2 3057700 3058551 no putative phosphoesterase (PHP family) 572 3NJ9A DNA polymerase alpha chain like domain S POORLY CHARACTERIZED Function unknown ACIAD3132 CDS +1 3058597 3059211 no putative intracellular septation protein (IspZ) 404 3NIMX probably involved in intracellular septation D CELLULAR PROCESSES AND SIGNALING Cell cycle control, cell division, chromosome partitioning ACIAD3133 CDS +3 3059244 3059546 no conserved hypothetical protein 209 3NNWH YCII-related domain S POORLY CHARACTERIZED Function unknown ACIAD3134 CDS +1 3059674 3059997 no conserved hypothetical protein; putative signal peptide 149 3NNHD S POORLY CHARACTERIZED Function unknown ACIAD3135 CDS +3 3060030 3061901 no putative tRNA 5-methylaminomethyl-2-thiouridine biosynthesis bifunctional protein mnmC 1289 3NJ9J Catalyzes the last two steps in the biosynthesis of 5- methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at the wobble position (U34) in tRNA. Catalyzes the FAD-dependent demodification of cmnm(5)s(2)U34 to nm(5)s(2)U34, followed by the transfer of a methyl group from S-adenosyl-L-methionine to nm(5)s(2)U34, to form mnm(5)s(2)U34 H METABOLISM Coenzyme transport and metabolism ACIAD3136 CDS -1 3061952 3062290 no conserved hypothetical protein; putative Rhodanese-related sulfurtransferase 225 3NNZW Rhodanese Homology Domain P METABOLISM Inorganic ion transport and metabolism ACIAD3137 CDS +3 3062358 3062846 no putative nucleotide binding protein 305 3NJQT Belongs to the UPF0234 family S POORLY CHARACTERIZED Function unknown ACIAD3138 CDS +3 3062850 3063374 no conserved hypothetical protein 341 3NKM9 Domain of unknown function (DUF4442) Q METABOLISM Secondary metabolites biosynthesis, transport and catabolism ACIAD3139 CDS -3 3063483 3063902 no putative acyl-CoA thioester hydrolase 280 3NN3Q Thioesterase superfamily I METABOLISM Lipid transport and metabolism ACIAD3140 CDS -2 3063916 3064341 no thi3 thioredoxin C-3 293 3NTMX Thioredoxin O CELLULAR PROCESSES AND SIGNALING Posttranslational modification, protein turnover, chaperones ACIAD3141 CDS -1 3064343 3065239 no putative hydrolase of the alpha/beta superfamily 606 3NKMY X-Pro dipeptidyl-peptidase (S15 family) S POORLY CHARACTERIZED Function unknown ACIAD3142 CDS +1 3065311 3065700 no conserved hypothetical protein; putative sulfide dehydrogenase (Flavocytochrome C) 264 3NNIA Putative phosphatase (DUF442) S POORLY CHARACTERIZED Function unknown ACIAD3143 CDS +2 3065756 3066115 no putative oxidoreductase 233 3NP21 Overlaps another CDS with the same product name S POORLY CHARACTERIZED Function unknown ACIAD3144 CDS -3 3066282 3068213 no conserved hypothetical protein 1112 3NMIK PFAM Ig domain protein, group 1 domain protein U CELLULAR PROCESSES AND SIGNALING Intracellular trafficking, secretion, and vesicular transport ACIAD3145 CDS +1 3068356 3069744 no putative dihydrolipoamide dehydrogenase E3 component of pyruvate/2-oxoglutarate dehydrogenase complex 914 3NK4N Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain C METABOLISM Energy production and conversion ACIAD3146 CDS +3 3069846 3070895 no mtnN methylthioadenosine / S-adenosylhomocysteine nucleosidase 691 3NPQP Phosphorylase superfamily F METABOLISM Nucleotide transport and metabolism ACIAD3148 CDS -2 3076909 3077985 no conserved hypothetical protein 735 3NIN6 S POORLY CHARACTERIZED Function unknown ACIAD3149 CDS -1 3078002 3078835 no pssA phosphatidylserine synthase 528 3NJG8 Belongs to the CDP-alcohol phosphatidyltransferase class-I family I METABOLISM Lipid transport and metabolism ACIAD3150 CDS -2 3078877 3079734 no putative ribosomal RNA large subunit methyltransferase J 595 3NKSQ Specifically methylates the adenine in position 2030 of 23S rRNA S POORLY CHARACTERIZED Function unknown ACIAD3151 CDS +2 3079847 3080455 no conserved hypothetical protein 424 3NK5X 2OG-Fe(II) oxygenase superfamily O CELLULAR PROCESSES AND SIGNALING Posttranslational modification, protein turnover, chaperones ACIAD3152 CDS +1 3080545 3081072 no conserved hypothetical protein 351 3NN3R S POORLY CHARACTERIZED Function unknown ACIAD3153 CDS -1 3081104 3081352 no conserved hypothetical protein 170 3NP9X Protein of unknown function (DUF2789) E METABOLISM Amino acid transport and metabolism ACIAD3155 CDS -2 3081535 3082521 no mdh malate dehydrogenase 645 3NIHG Catalyzes the reversible oxidation of malate to oxaloacetate C METABOLISM Energy production and conversion ACIAD3156 CDS -3 3082701 3083420 no conserved hypothetical protein 481 3NJNV Belongs to the RNase T2 family J INFORMATION STORAGE AND PROCESSING Translation, ribosomal structure and biogenesis ACIAD3157 CDS -2 3083401 3085443 no putative lytic murein transglycosylase, soluble (Slt) 1356 3NJXX COG0741 Soluble lytic murein transglycosylase and related regulatory proteins (some contain LysM invasin domains) M CELLULAR PROCESSES AND SIGNALING Cell wall/membrane/envelope biogenesis ACIAD3158 CDS +3 3085632 3087083 no putative tRNA-i(6)A37 modification enzyme (MiaB) 965 3NK7G Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine J INFORMATION STORAGE AND PROCESSING Translation, ribosomal structure and biogenesis ACIAD3159 CDS +1 3087124 3088206 no phoL phosphate starvation-inducible protein (PhoH-like) 691 3NJNA PhoH-like protein T CELLULAR PROCESSES AND SIGNALING Signal transduction mechanisms ACIAD3160 CDS +3 3088290 3088769 no putative metalloprotease ybeY-like 311 3NMDH Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA J INFORMATION STORAGE AND PROCESSING Translation, ribosomal structure and biogenesis ACIAD3161 CDS -2 3088813 3090969 no putative outer membrane porin, receptor for Fe(III)-coprogen, Fe(III)-ferrioxamine B and Fe(III)-rhodotrulic acid uptake (fhuE) 1448 3NIRU TonB dependent receptor P METABOLISM Inorganic ion transport and metabolism ACIAD3162 CDS +2 3091445 3092143 no conserved hypothetical protein 401 3NJK3 S POORLY CHARACTERIZED Function unknown ACIAD3163 CDS +1 3092263 3093015 no conserved hypothetical protein 485 3NKQM Protein of unknown function (DUF3108) S POORLY CHARACTERIZED Function unknown ACIAD3164 CDS +3 3093126 3093737 no xpt xanthine phosphoribosyltransferase 383 3NJDE Converts the preformed base xanthine, a product of nucleic acid breakdown, to xanthosine 5'-monophosphate (XMP), so it can be reused for RNA or DNA synthesis F METABOLISM Nucleotide transport and metabolism ACIAD3165 CDS +3 3093861 3094289 no conserved hypothetical protein 173 3NNIV S POORLY CHARACTERIZED Function unknown ACIAD3166 CDS -3 3094347 3094982 no putative amino-acid efflux transmembrane protein 400 3NTET LysE type translocator E METABOLISM Amino acid transport and metabolism ACIAD3167 CDS -1 3095051 3095650 no wrbA tryptophan repressor binding protein 406 3NISH Belongs to the WrbA family S POORLY CHARACTERIZED Function unknown ACIAD3168 CDS +3 3095748 3097007 no putative ribonuclease (Rbn) 806 3NIPH UPF0761 membrane protein S POORLY CHARACTERIZED Function unknown ACIAD3169 CDS -3 3097068 3097979 no putative transcriptional regulator (LysR family) 585 3NIVN LysR substrate binding domain K INFORMATION STORAGE AND PROCESSING Transcription ACIAD3170 CDS +3 3098112 3099398 no putative transporter (MFS superfamily) 814 3NJDF Sugar (and other) transporter E METABOLISM Amino acid transport and metabolism ACIAD3170 CDS +3 3098112 3099398 no putative transporter (MFS superfamily) 814 3NJDF Sugar (and other) transporter G METABOLISM Carbohydrate transport and metabolism ACIAD3170 CDS +3 3098112 3099398 no putative transporter (MFS superfamily) 814 3NJDF Sugar (and other) transporter P METABOLISM Inorganic ion transport and metabolism ACIAD3172 CDS -1 3099662 3100306 no conserved hypothetical protein; putative fumarylacetoacetate hydrolase family protein 451 3NIJ2 Fumarylacetoacetate (FAA) hydrolase family Q METABOLISM Secondary metabolites biosynthesis, transport and catabolism ACIAD3173 CDS -3 3100338 3100886 no conserved hypothetical protein; putative membrane protein 354 3NJH9 S POORLY CHARACTERIZED Function unknown ACIAD3174 CDS +3 3101025 3102329 no conserved hypothetical protein 853 3NM47 S POORLY CHARACTERIZED Function unknown ACIAD3175 CDS -3 3102585 3102866 no hypothetical protein 184 3NS44 S POORLY CHARACTERIZED Function unknown ACIAD3176 CDS -2 3103183 3104442 no putative sensory transduction histidine kinase 824 3NTAZ His Kinase A (phosphoacceptor) domain T CELLULAR PROCESSES AND SIGNALING Signal transduction mechanisms ACIAD3177 CDS +1 3105181 3107250 no conserved hypothetical protein; putative conserved domain 861 3NKTT Hep Hag repeat protein U CELLULAR PROCESSES AND SIGNALING Intracellular trafficking, secretion, and vesicular transport ACIAD3177 CDS +1 3105181 3107250 no conserved hypothetical protein; putative conserved domain 861 3NKTT Hep Hag repeat protein W CELLULAR PROCESSES AND SIGNALING Extracellular structures ACIAD3179 CDS +3 3107961 3110414 no rnr exoribonuclease R 1532 3NJ9W 3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs J INFORMATION STORAGE AND PROCESSING Translation, ribosomal structure and biogenesis ACIAD3182 CDS +3 3110802 3112856 no prlC oligopeptidase A 1355 3NJ7Q Peptidase family M3 E METABOLISM Amino acid transport and metabolism ACIAD3183 CDS +2 3112862 3113101 no conserved hypothetical protein 167 3NPFP Probable metal-binding protein (DUF2387) S POORLY CHARACTERIZED Function unknown ACIAD3184 CDS -2 3113146 3115422 no putative integral membrane protein, possible transporter 1451 3NKX6 Tripartite ATP-independent periplasmic transporter, DctM component G METABOLISM Carbohydrate transport and metabolism ACIAD3185 CDS -2 3115504 3116085 no conserved hypothetical protein; putative membrane protein 395 3NIWX Rhomboid family S POORLY CHARACTERIZED Function unknown ACIAD3186 CDS -1 3116171 3117256 no conserved hypothetical protein 706 3NJCV S POORLY CHARACTERIZED Function unknown ACIAD3188 CDS -1 3117803 3118195 no conserved hypothetical protein; putative membrane protein 262 3NPWK S POORLY CHARACTERIZED Function unknown ACIAD3189 CDS -3 3118182 3118439 no conserved hypothetical protein 172 3NPAM Flavinator of succinate dehydrogenase S POORLY CHARACTERIZED Function unknown ACIAD3191 CDS +2 3118628 3119800 no acads2 Acyl-CoA dehydrogenase, short-chain specific 787 3NJJS Acyl-CoA dehydrogenase, C-terminal domain I METABOLISM Lipid transport and metabolism ACIAD3192 CDS -3 3119865 3121361 no almA monooxygenase involved in long chain alcane degradation 1010 3NKP3 Flavin-binding monooxygenase-like P METABOLISM Inorganic ion transport and metabolism ACIAD3193 CDS -3 3121527 3121904 no rplQ 50S ribosomal protein L17 239 3NN8W Ribosomal protein L17 J INFORMATION STORAGE AND PROCESSING Translation, ribosomal structure and biogenesis ACIAD3194 CDS -3 3121923 3122930 no rpoA RNA polymerase, alpha subunit 642 3NIZA DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates K INFORMATION STORAGE AND PROCESSING Transcription ACIAD3195 CDS -3 3122949 3123572 no rpsD 30S ribosomal protein S4 400 3NJVB One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit J INFORMATION STORAGE AND PROCESSING Translation, ribosomal structure and biogenesis ACIAD3196 CDS -3 3123585 3123971 no rpsK 30S ribosomal protein S11 250 3NN3C Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome J INFORMATION STORAGE AND PROCESSING Translation, ribosomal structure and biogenesis ACIAD3197 CDS -2 3123991 3124347 no rpsM 30S ribosomal protein S13 228 3NNKC Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits J INFORMATION STORAGE AND PROCESSING Translation, ribosomal structure and biogenesis ACIAD3198 CDS -1 3124454 3124570 no rpmJ 50S ribosomal protein L36 77 3NQ70 Belongs to the bacterial ribosomal protein bL36 family J INFORMATION STORAGE AND PROCESSING Translation, ribosomal structure and biogenesis ACIAD3199 CDS -2 3124591 3125949 no secY secretion protein 860 3NIK2 The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently U CELLULAR PROCESSES AND SIGNALING Intracellular trafficking, secretion, and vesicular transport ACIAD3200 CDS -2 3125956 3126396 no rplO 50S ribosomal protein L15 266 3NN66 binds to the 23S rRNA J INFORMATION STORAGE AND PROCESSING Translation, ribosomal structure and biogenesis ACIAD3201 CDS -2 3126400 3126576 no rpmD 50S ribosomal protein L30 116 3NPR9 Ribosomal protein L30 J INFORMATION STORAGE AND PROCESSING Translation, ribosomal structure and biogenesis ACIAD3202 CDS -2 3126583 3127080 no rpsE 30S ribosomal protein S5 309 3NJBV Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body J INFORMATION STORAGE AND PROCESSING Translation, ribosomal structure and biogenesis ACIAD3203 CDS -3 3127083 3127433 no rplR 50S ribosomal protein L18 213 3NNGJ This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance J INFORMATION STORAGE AND PROCESSING Translation, ribosomal structure and biogenesis ACIAD3204 CDS -1 3127448 3127981 no rplF 50S ribosomal protein L6 342 3NIFW This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center J INFORMATION STORAGE AND PROCESSING Translation, ribosomal structure and biogenesis ACIAD3205 CDS -3 3127995 3128390 no rpsH 30S ribosomal protein S8 238 3NN47 One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit J INFORMATION STORAGE AND PROCESSING Translation, ribosomal structure and biogenesis ACIAD3206 CDS -3 3128403 3128708 no rpsN 30S ribosomal protein S14 199 3NNIJ Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site J INFORMATION STORAGE AND PROCESSING Translation, ribosomal structure and biogenesis ACIAD3207 CDS -3 3128718 3129254 no rplE 50S ribosomal protein L5 347 3NIKY This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits J INFORMATION STORAGE AND PROCESSING Translation, ribosomal structure and biogenesis ACIAD3208 CDS -3 3129270 3129590 no rplX 50S ribosomal protein L24 203 3NP82 One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit J INFORMATION STORAGE AND PROCESSING Translation, ribosomal structure and biogenesis ACIAD3209 CDS -3 3129600 3129968 no rplN 50S ribosomal protein L14 238 3NN4P Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome J INFORMATION STORAGE AND PROCESSING Translation, ribosomal structure and biogenesis ACIAD3210 CDS -3 3130059 3130316 no rpsQ 30S ribosomal protein S17 163 3NNW9 One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA J INFORMATION STORAGE AND PROCESSING Translation, ribosomal structure and biogenesis ACIAD3211 CDS -1 3130313 3130510 no rpmC 50S ribosomal protein L29 118 3NPA8 Belongs to the universal ribosomal protein uL29 family J INFORMATION STORAGE AND PROCESSING Translation, ribosomal structure and biogenesis ACIAD3212 CDS -2 3130510 3130923 no rplP 50S ribosomal protein L16 267 3NN5W Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs J INFORMATION STORAGE AND PROCESSING Translation, ribosomal structure and biogenesis ACIAD3213 CDS -2 3130927 3131679 no rpsC 30S ribosomal protein S3 474 3NK5Y Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation J INFORMATION STORAGE AND PROCESSING Translation, ribosomal structure and biogenesis ACIAD3214 CDS -1 3131681 3132013 no rplV 50S ribosomal protein L22 206 3NNGH The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome J INFORMATION STORAGE AND PROCESSING Translation, ribosomal structure and biogenesis ACIAD3215 CDS -2 3132022 3132297 no rpsS 30S ribosomal protein S19 188 3NNXA Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA J INFORMATION STORAGE AND PROCESSING Translation, ribosomal structure and biogenesis ACIAD3216 CDS -1 3132311 3133135 no rplB 50S ribosomal protein L2 554 3NK9Q One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity J INFORMATION STORAGE AND PROCESSING Translation, ribosomal structure and biogenesis ACIAD3217 CDS -2 3133147 3133467 no rplW 50S ribosomal protein L23 199 3NNHP One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome J INFORMATION STORAGE AND PROCESSING Translation, ribosomal structure and biogenesis ACIAD3218 CDS -3 3133464 3134081 no rplD 50S ribosomal protein L4, regulates expression of S10 operon 385 3NK1G Forms part of the polypeptide exit tunnel J INFORMATION STORAGE AND PROCESSING Translation, ribosomal structure and biogenesis ACIAD3219 CDS -1 3134078 3134716 no rplC 50S ribosomal protein L3 414 3NJ2J One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit J INFORMATION STORAGE AND PROCESSING Translation, ribosomal structure and biogenesis ACIAD3220 CDS -2 3134776 3135102 no rpsJ 30S ribosomal protein S10 212 3NNK0 Involved in the binding of tRNA to the ribosomes J INFORMATION STORAGE AND PROCESSING Translation, ribosomal structure and biogenesis ACIAD3221 CDS -3 3135351 3136091 no conserved hypothetical protein; putative glutamine amidotransferase 504 3NK9A Glutamine amidotransferase class-I F METABOLISM Nucleotide transport and metabolism ACIAD3222 CDS +1 3136252 3137445 no putative cystathionine beta-lyase, PLP-dependent (beta-cystathionase) (MetC) 811 3NJ2T Cys/Met metabolism PLP-dependent enzyme E METABOLISM Amino acid transport and metabolism ACIAD3223 CDS +3 3137469 3139007 no putative enzyme contains P-loop containing nucleotide triphosphate hydrolase domain 925 3NJKC Bacterial protein of unknown function (DUF853) S POORLY CHARACTERIZED Function unknown ACIAD3225 CDS +1 3139321 3140220 no putative transcriptional regulator 579 3NM6H LysR substrate binding domain K INFORMATION STORAGE AND PROCESSING Transcription ACIAD3226 CDS +2 3140306 3141070 no putative flavohemoprotein 505 3NT86 Globin C METABOLISM Energy production and conversion ACIAD3227 CDS +3 3141165 3141602 no putative transcriptional regulator, 294 3NNKA Transcriptional regulator K INFORMATION STORAGE AND PROCESSING Transcription ACIAD3228 CDS +3 3141657 3142541 no putative GTPase, involved in coordination of cell cycle (EngB) 519 3NJ14 Necessary for normal cell division and for the maintenance of normal septation D CELLULAR PROCESSES AND SIGNALING Cell cycle control, cell division, chromosome partitioning ACIAD3229 CDS +1 3142675 3143625 no conserved hypothetical protein 652 3NIT0 Predicted metal-dependent hydrolase S POORLY CHARACTERIZED Function unknown ACIAD3230 CDS -1 3143711 3144952 no putative Proton/sodium-glutamate symport protein 751 3NJTM Catalyzes the proton-dependent transport of glutamate and aspartate U CELLULAR PROCESSES AND SIGNALING Intracellular trafficking, secretion, and vesicular transport ACIAD3231 CDS -1 3145034 3145906 no tesB acyl-CoA thioesterase II 582 3NINR Acyl-CoA thioesterase I METABOLISM Lipid transport and metabolism ACIAD3232 CDS +3 3146193 3148757 no plsB glycerol-3-phosphate acyltransferase 1667 3NIHA Belongs to the GPAT DAPAT family I METABOLISM Lipid transport and metabolism ACIAD3233 CDS -1 3148802 3149791 no putative RND type efflux pump involved in aminoglycoside resistance (adeT) 660 3NJKA TRAP-type C4-dicarboxylate transport system periplasmic component G METABOLISM Carbohydrate transport and metabolism ACIAD3234 CDS -2 3149923 3150804 no conserved hypothetical protein; putative nucleoside-diphosphate-sugar epimerase 601 3NKHY NAD(P)H-binding G METABOLISM Carbohydrate transport and metabolism ACIAD3234 CDS -2 3149923 3150804 no conserved hypothetical protein; putative nucleoside-diphosphate-sugar epimerase 601 3NKHY NAD(P)H-binding M CELLULAR PROCESSES AND SIGNALING Cell wall/membrane/envelope biogenesis ACIAD3235 CDS +3 3150747 3152807 no recG ATP-dependent DNA helicase 1348 3NJA4 Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA) L INFORMATION STORAGE AND PROCESSING Replication, recombination and repair ACIAD3236 CDS +1 3152794 3153435 no putative DNA transformation protein (ComF) 427 3NJV7 competence protein S POORLY CHARACTERIZED Function unknown ACIAD3237 CDS -2 3153439 3153843 no conserved hypothetical protein; putative MutT/nudix family protein 266 3NNGI NUDIX domain F METABOLISM Nucleotide transport and metabolism ACIAD3238 CDS -2 3153856 3154455 no putative hydrolase 409 3NSP7 Belongs to the LOG family S POORLY CHARACTERIZED Function unknown ACIAD3239 CDS +3 3154524 3155612 no corA magnesium and cobalt transport protein 714 3NJGZ CorA-like Mg2+ transporter protein P METABOLISM Inorganic ion transport and metabolism ACIAD3240 CDS -3 3155664 3155960 no putative toluene-tolerance protein (Ttg2E) 194 3NPAK STAS domain S POORLY CHARACTERIZED Function unknown ACIAD3241 CDS -2 3155971 3156609 no putative toluene tolerance protein (Ttg2D) 414 3NJPG MlaC protein Q METABOLISM Secondary metabolites biosynthesis, transport and catabolism ACIAD3242 CDS -2 3156622 3157293 no ttg2C toluene tolerance efflux transporter (ABC superfamily, peri-bind) 416 3NJ1Q MlaD protein Q METABOLISM Secondary metabolites biosynthesis, transport and catabolism ACIAD3243 CDS -3 3157293 3158069 no ttg2B toluene tolerance efflux transporter (ABC superfamily, membrane) 481 3NM1S Permease MlaE Q METABOLISM Secondary metabolites biosynthesis, transport and catabolism ACIAD3244 CDS -1 3158066 3158884 no ttg2A toluene tolerance efflux transporter (ABC superfamily, atp_bind) 529 3NJ5K ATPases associated with a variety of cellular activities Q METABOLISM Secondary metabolites biosynthesis, transport and catabolism ACIAD3245 CDS -3 3159264 3161186 no putative ATP-dependent RNA helicase 939 3NIUV Belongs to the DEAD box helicase family L INFORMATION STORAGE AND PROCESSING Replication, recombination and repair ACIAD3246 CDS -3 3161553 3162383 no suhB inositol-1-monophosphatase (IMPase) (Inositol-1- phosphatase) (I-1-Pase) 555 3NIYZ Inositol monophosphatase G METABOLISM Carbohydrate transport and metabolism ACIAD3247 CDS -1 3162500 3164422 no dxs 1-deoxyxylulose-5-phosphate synthase 1293 3NIWY Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP) H METABOLISM Coenzyme transport and metabolism ACIAD3249 CDS +3 3164715 3165317 no ribA GTP cyclohydrolase II 399 3NJJB Catalyzes the conversion of GTP to 2,5-diamino-6- ribosylamino-4(3H)-pyrimidinone 5'-phosphate (DARP), formate and pyrophosphate H METABOLISM Coenzyme transport and metabolism ACIAD3250 CDS +3 3165390 3166370 no hemF coproporphyrinogen III oxidase 684 3NJJ9 Involved in the heme biosynthesis. Catalyzes the aerobic oxidative decarboxylation of propionate groups of rings A and B of coproporphyrinogen-III to yield the vinyl groups in protoporphyrinogen-IX H METABOLISM Coenzyme transport and metabolism ACIAD3253 CDS +2 3166583 3166789 no hypothetical protein, putative membrane protein 132 3NQDY S POORLY CHARACTERIZED Function unknown ACIAD3254 CDS -1 3166832 3167479 no putative metal-binding hydrolase 454 3NIMB Metallo-beta-lactamase superfamily S POORLY CHARACTERIZED Function unknown ACIAD3255 CDS -1 3167492 3168514 no hemH ferrochelatase 687 3NJ4U Catalyzes the ferrous insertion into protoporphyrin IX H METABOLISM Coenzyme transport and metabolism ACIAD3256 CDS -3 3168573 3169610 no conserved hypothetical protein; putative conserved domain 691 3NITG Domain of unknown function (DUF4062) S POORLY CHARACTERIZED Function unknown ACIAD3257 CDS -2 3169717 3170595 no murI glutamate racemase 585 3NIIW Provides the (R)-glutamate required for cell wall biosynthesis M CELLULAR PROCESSES AND SIGNALING Cell wall/membrane/envelope biogenesis ACIAD3258 CDS -1 3170642 3171253 no conserved hypothetical protein 408 3NSQ7 Protein of unknown function (DUF1285) S POORLY CHARACTERIZED Function unknown ACIAD3259 CDS +1 3171439 3173151 no etfD electron transfer flavoprotein-ubiquinone oxidoreductase (ETF-QO) (ETF-ubiquinone oxidoreductase) (ETF dehydrogenase) (Electron-transferring-flavoprotein dehydrogenase) 1194 3NK8K Electron transfer flavoprotein-ubiquinone oxidoreductase C METABOLISM Energy production and conversion ACIAD3261 CDS -2 3173239 3175515 no conserved hypothetical protein; putative signal peptide 1461 3NJYZ S POORLY CHARACTERIZED Function unknown ACIAD3262 CDS +1 3175753 3177576 no putative acyl-CoA dehydrogenase 1228 3NK5D acyl-CoA dehydrogenase I METABOLISM Lipid transport and metabolism ACIAD3263 CDS -3 3177618 3178283 no conserved hypothetical protein 449 3NKUP S POORLY CHARACTERIZED Function unknown ACIAD3264 CDS +2 3178571 3178840 no conserved hypothetical protein 178 3NPCM PspC domain K INFORMATION STORAGE AND PROCESSING Transcription ACIAD3264 CDS +2 3178571 3178840 no conserved hypothetical protein 178 3NPCM PspC domain T CELLULAR PROCESSES AND SIGNALING Signal transduction mechanisms ACIAD3266 CDS -2 3178909 3180027 no conserved hypothetical protein; putative membrane protein 733 3NJW5 HPP family T CELLULAR PROCESSES AND SIGNALING Signal transduction mechanisms ACIAD3267 CDS -1 3180113 3181279 no putative hydrolase 790 3NN2H Esterase PHB depolymerase Q METABOLISM Secondary metabolites biosynthesis, transport and catabolism ACIAD3268 CDS +3 3181266 3182243 no glyQ glycyl-tRNA synthetase, alpha chain 653 3NIRE glycyl-tRNA synthetase, alpha subunit J INFORMATION STORAGE AND PROCESSING Translation, ribosomal structure and biogenesis ACIAD3269 CDS +2 3182243 3184312 no glyS glycyl-tRNA synthetase, beta chain 1310 3NIHP Glycyl-tRNA synthetase beta subunit J INFORMATION STORAGE AND PROCESSING Translation, ribosomal structure and biogenesis ACIAD3270 CDS +2 3184532 3185536 no conserved hypothetical protein; putative cytoplasmic protein 665 3NPPX SEC-C Motif Domain Protein S POORLY CHARACTERIZED Function unknown ACIAD3271 fCDS -3 3185718 3185897 pseudo fragment of conserved hypothetical protein (part 2) 114 3NP50 YCII-related domain S POORLY CHARACTERIZED Function unknown ACIAD3272 fCDS -3 3185901 3186002 pseudo fragment of conserved hypothetical protein (part 1) 65.5 3NP50 YCII-related domain S POORLY CHARACTERIZED Function unknown ACIAD3273 CDS -2 3186070 3186972 no putative transporter 592 3NMU0 EamA-like transporter family E METABOLISM Amino acid transport and metabolism ACIAD3273 CDS -2 3186070 3186972 no putative transporter 592 3NMU0 EamA-like transporter family G METABOLISM Carbohydrate transport and metabolism ACIAD3274 CDS +1 3187102 3187956 no putative transcriptional regulator (LysR family) 580 3NJVW LysR substrate binding domain K INFORMATION STORAGE AND PROCESSING Transcription ACIAD3276 CDS +1 3188035 3188424 no conserved hypothetical protein; putative signal peptide 255 3NP5E S POORLY CHARACTERIZED Function unknown ACIAD3277 CDS +1 3188587 3189084 no conserved hypothetical protein; putative signal peptide 306 3NN67 S POORLY CHARACTERIZED Function unknown ACIAD3278 CDS -2 3189088 3190044 no hprA glycerate dehydrogenase 622 3NJ61 Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family C METABOLISM Energy production and conversion ACIAD3278 CDS -2 3189088 3190044 no hprA glycerate dehydrogenase 622 3NJ61 Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family H METABOLISM Coenzyme transport and metabolism ACIAD3279 CDS +1 3190351 3190953 no conserved hypothetical protein; putative signal peptide 303 3NNCR S POORLY CHARACTERIZED Function unknown ACIAD3280 CDS -2 3191038 3192303 no conserved hypothetical protein 826 3NJ0Q alpha beta S POORLY CHARACTERIZED Function unknown ACIAD3281 CDS -1 3192464 3193357 no dkg 2,5-diketo-D-gluconate reductase 591 3NJFD Aldo/keto reductase family S POORLY CHARACTERIZED Function unknown ACIAD3283 CDS +2 3193523 3194293 no conserved hypothetical protein; putative SAM-dependent methyltransferase 518 3NJSN Methyltransferase domain Q METABOLISM Secondary metabolites biosynthesis, transport and catabolism ACIAD3284 CDS +2 3194318 3194872 no conserved hypothetical protein; putative signal peptide 353 3NJQ3 S POORLY CHARACTERIZED Function unknown ACIAD3285 CDS -1 3194915 3195487 no conserved hypothetical protein; putative signal peptide 386 3NJHW S POORLY CHARACTERIZED Function unknown ACIAD3286 CDS -1 3195596 3196048 no conserved hypothetical protein 286 3NIH0 Endonuclease related to archaeal Holliday junction resolvase F METABOLISM Nucleotide transport and metabolism ACIAD3288 CDS +2 3196187 3196831 no putative partition-related protein 414 3NKP0 VirC1 protein D CELLULAR PROCESSES AND SIGNALING Cell cycle control, cell division, chromosome partitioning ACIAD3289 CDS +2 3196958 3198070 no conserved hypothetical protein; putative membrane protein 706 3NIJR AI-2E family transporter S POORLY CHARACTERIZED Function unknown ACIAD3290 CDS +3 3198366 3198977 no conserved hypothetical protein; putative NADH-flavin reductase 402 1S0ZG 3-beta hydroxysteroid dehydrogenase S POORLY CHARACTERIZED Function unknown ACIAD3291 CDS +1 3199153 3201303 no conserved hypothetical protein; putative membrane protein 1330 3NJZ8 FUSC-like inner membrane protein yccS S POORLY CHARACTERIZED Function unknown ACIAD3292 CDS -3 3201357 3202586 no mdfA multidrug/chloramphenicol efflux transport protein (MFS superfamily) 767 3NJNY Sugar (and other) transporter E METABOLISM Amino acid transport and metabolism ACIAD3292 CDS -3 3201357 3202586 no mdfA multidrug/chloramphenicol efflux transport protein (MFS superfamily) 767 3NJNY Sugar (and other) transporter G METABOLISM Carbohydrate transport and metabolism ACIAD3292 CDS -3 3201357 3202586 no mdfA multidrug/chloramphenicol efflux transport protein (MFS superfamily) 767 3NJNY Sugar (and other) transporter P METABOLISM Inorganic ion transport and metabolism ACIAD3295 CDS +3 3203073 3203693 no mdaB modulator of drug activity, similar to electron transfer flavoprotein-NAD/FAD/quinone oxidoreductase 421 3NM09 Flavodoxin-like fold S POORLY CHARACTERIZED Function unknown ACIAD3296 CDS +2 3203690 3204007 no putative monooxygenase 207 3NNXW Antibiotic biosynthesis monooxygenase S POORLY CHARACTERIZED Function unknown ACIAD3297 CDS -2 3204103 3205662 no putative cytidine / deoxycytidylate deaminase family protein 1010 3NMDQ MafB19-like deaminase F METABOLISM Nucleotide transport and metabolism ACIAD3298 CDS -3 3206031 3206837 no putative short-chain dehydrogenase 530 3NT09 KR domain S POORLY CHARACTERIZED Function unknown ACIAD3299 CDS -3 3207081 3207461 no conserved hypothetical protein; putative signal peptide 241 3NNH9 S POORLY CHARACTERIZED Function unknown ACIAD3300 CDS -1 3207551 3208960 no putative FAD/FMN-containing dehydrogenase 943 3NJUR FAD linked oxidases, C-terminal domain C METABOLISM Energy production and conversion ACIAD3302 CDS +2 3209228 3210460 no serA D-3-phosphoglycerate dehydrogenase 801 3NINV Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family E METABOLISM Amino acid transport and metabolism ACIAD3302 CDS +2 3209228 3210460 no serA D-3-phosphoglycerate dehydrogenase 801 3NINV Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family H METABOLISM Coenzyme transport and metabolism ACIAD3303 CDS +1 3210553 3211440 no putative amino acid efflux system 555 3NJ10 EamA-like transporter family S POORLY CHARACTERIZED Function unknown ACIAD3304 CDS +1 3211516 3212403 no putative amino acid efflux system 566 3NIXZ EamA-like transporter family S POORLY CHARACTERIZED Function unknown ACIAD3305 CDS -2 3212419 3212868 no conserved hypothetical protein 288 3NN55 Hemerythrin HHE cation binding domain S POORLY CHARACTERIZED Function unknown ACIAD3306 CDS -1 3213017 3213787 no conserved hypothetical protein; putative membrane protein 473 3NJ1S membrane transporter protein S POORLY CHARACTERIZED Function unknown ACIAD3307 CDS -1 3213800 3214756 no truB tRNA pseudouridine 55 synthase 638 3NJN4 Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs J INFORMATION STORAGE AND PROCESSING Translation, ribosomal structure and biogenesis ACIAD3308 CDS +3 3214851 3215882 no lifO lipase chaperone (Lipase foldase) (Lipase helper protein) (Lipase activator protein) (Lipase modulator) 660 3NSPZ May be involved in the folding of the extracellular lipase during its passage through the periplasm O CELLULAR PROCESSES AND SIGNALING Posttranslational modification, protein turnover, chaperones ACIAD3309 CDS +2 3216014 3216982 no lipase 639 3NJGV alpha/beta hydrolase fold S POORLY CHARACTERIZED Function unknown ACIAD3310 CDS -1 3217052 3217423 no rplS 50S ribosomal protein L19 234 3NN51 This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site J INFORMATION STORAGE AND PROCESSING Translation, ribosomal structure and biogenesis ACIAD3311 CDS -1 3217565 3218314 no trmD tRNA (guanine-1-)-methyltransferase. 508 3NJ5E Belongs to the RNA methyltransferase TrmD family J INFORMATION STORAGE AND PROCESSING Translation, ribosomal structure and biogenesis ACIAD3312 CDS -2 3218362 3218910 no rimM 16S rRNA processing protein 379 3NJ2R An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes J INFORMATION STORAGE AND PROCESSING Translation, ribosomal structure and biogenesis ACIAD3313 CDS -1 3218930 3219187 no rpsP 30S ribosomal protein S16 161 3NNWP Belongs to the bacterial ribosomal protein bS16 family J INFORMATION STORAGE AND PROCESSING Translation, ribosomal structure and biogenesis ACIAD3314 CDS -1 3219335 3219769 no comF type IV pilus assembly protein ComF 281 3NNR0 Type IV minor pilin ComP, DNA uptake sequence receptor N CELLULAR PROCESSES AND SIGNALING Cell motility ACIAD3314 CDS -1 3219335 3219769 no comF type IV pilus assembly protein ComF 281 3NNR0 Type IV minor pilin ComP, DNA uptake sequence receptor U CELLULAR PROCESSES AND SIGNALING Intracellular trafficking, secretion, and vesicular transport ACIAD3315 CDS -2 3219769 3220278 no comE type IV pilus assembly protein ComE 318 3NP0M Prokaryotic N-terminal methylation motif N CELLULAR PROCESSES AND SIGNALING Cell motility ACIAD3315 CDS -2 3219769 3220278 no comE type IV pilus assembly protein ComE 318 3NP0M Prokaryotic N-terminal methylation motif U CELLULAR PROCESSES AND SIGNALING Intracellular trafficking, secretion, and vesicular transport ACIAD3316 CDS -1 3220340 3224692 no comC competence factor involved in DNA binding and uptake 2867 3NKHS Tfp pilus assembly protein tip-associated adhesin PilY1 N CELLULAR PROCESSES AND SIGNALING Cell motility ACIAD3316 CDS -1 3220340 3224692 no comC competence factor involved in DNA binding and uptake 2867 3NKHS Tfp pilus assembly protein tip-associated adhesin PilY1 U CELLULAR PROCESSES AND SIGNALING Intracellular trafficking, secretion, and vesicular transport ACIAD3317 CDS -3 3224709 3225377 no pilX type IV pilus assembly protein PilX 359 3NMG3 S POORLY CHARACTERIZED Function unknown ACIAD3318 CDS -1 3225374 3226342 no comB pilin like competence factor 616 3NMPE Type IV Pilus-assembly protein W N CELLULAR PROCESSES AND SIGNALING Cell motility ACIAD3318 CDS -1 3225374 3226342 no comB pilin like competence factor 616 3NMPE Type IV Pilus-assembly protein W U CELLULAR PROCESSES AND SIGNALING Intracellular trafficking, secretion, and vesicular transport ACIAD3319 CDS -1 3226343 3226885 no putative type 4 fimbrial biogenesis protein (PilV) 337 3NTIK type IV pilus modification protein PilV N CELLULAR PROCESSES AND SIGNALING Cell motility ACIAD3319 CDS -1 3226343 3226885 no putative type 4 fimbrial biogenesis protein (PilV) 337 3NTIK type IV pilus modification protein PilV U CELLULAR PROCESSES AND SIGNALING Intracellular trafficking, secretion, and vesicular transport ACIAD3321 CDS -2 3226876 3227322 no FimU type IV pilus assembly protein FimU 273 3NNBB Prokaryotic N-terminal methylation motif N CELLULAR PROCESSES AND SIGNALING Cell motility ACIAD3321 CDS -2 3226876 3227322 no FimU type IV pilus assembly protein FimU 273 3NNBB Prokaryotic N-terminal methylation motif U CELLULAR PROCESSES AND SIGNALING Intracellular trafficking, secretion, and vesicular transport ACIAD3322 CDS -2 3227449 3228399 no ispH 4-hydroxy-3-methylbut-2-enyl diphosphate reductase (also involved in penicillin tolerance and control of the stringent response. Seems to directly or indirectly interact with relA to maintain it in an inactive form during normal growth.) 628 3NK2E Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis I METABOLISM Lipid transport and metabolism ACIAD3322 CDS -2 3227449 3228399 no ispH 4-hydroxy-3-methylbut-2-enyl diphosphate reductase (also involved in penicillin tolerance and control of the stringent response. Seems to directly or indirectly interact with relA to maintain it in an inactive form during normal growth.) 628 3NK2E Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis M CELLULAR PROCESSES AND SIGNALING Cell wall/membrane/envelope biogenesis ACIAD3324 CDS +3 3228534 3229157 no gmk guanylate kinase 407 3NKHV Essential for recycling GMP and indirectly, cGMP F METABOLISM Nucleotide transport and metabolism ACIAD3325 CDS +2 3229226 3229507 no rpoZ RNA polymerase, omega subunit 184 3NNVY Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits K INFORMATION STORAGE AND PROCESSING Transcription ACIAD3326 CDS +1 3229846 3231960 no putative bifunctional protein (SpoT) [Includes: guanosine-3',5'-bis pyrophosphate 3'-pyrophosphohydrolase; (p)ppGpp synthetase II] 1414 3NIQY HD domain K INFORMATION STORAGE AND PROCESSING Transcription ACIAD3326 CDS +1 3229846 3231960 no putative bifunctional protein (SpoT) [Includes: guanosine-3',5'-bis pyrophosphate 3'-pyrophosphohydrolase; (p)ppGpp synthetase II] 1414 3NIQY HD domain T CELLULAR PROCESSES AND SIGNALING Signal transduction mechanisms ACIAD3327 CDS +2 3232037 3232420 no putative 2-iminobutanoate/2-iminopropanoate deaminase (RidA like) 251 3NN5J Endoribonuclease L-PSP J INFORMATION STORAGE AND PROCESSING Translation, ribosomal structure and biogenesis ACIAD3328 CDS +2 3232559 3232768 no putative regulatory or redox component complexing with Bfr, in iron storage and mobility (Bfd) 138 3NPA9 BFD-like [2Fe-2S] binding domain P METABOLISM Inorganic ion transport and metabolism ACIAD3330 CDS +2 3233069 3233494 no bfrB bacterioferritin 279 3NKDB Iron-storage protein, whose ferroxidase center binds Fe(2 ) ions, oxidizes them by dioxygen to Fe(3 ), and participates in the subsequent Fe(3 ) oxide mineral core formation within the central cavity of the protein complex P METABOLISM Inorganic ion transport and metabolism ACIAD3332 CDS +1 3233797 3234270 no conserved hypothetical protein 300 3NPQ4 Spore Coat Protein U domain S POORLY CHARACTERIZED Function unknown ACIAD3333 CDS -3 3234267 3235172 no conserved hypothetical protein; putative lipoprotein signal peptide 607 3NMQP Spore Coat Protein U domain S POORLY CHARACTERIZED Function unknown ACIAD3334 CDS -1 3235250 3237604 no putative usher protein involved in fimbrial biogenesis (PapC/CsuD) 1551 3NKPQ Outer membrane usher protein N CELLULAR PROCESSES AND SIGNALING Cell motility ACIAD3334 CDS -1 3235250 3237604 no putative usher protein involved in fimbrial biogenesis (PapC/CsuD) 1551 3NKPQ Outer membrane usher protein U CELLULAR PROCESSES AND SIGNALING Intracellular trafficking, secretion, and vesicular transport ACIAD3335 CDS -3 3237618 3238340 no putative pili assembly chaperone (PapD-like) 471 3NSQG Pili and flagellar-assembly chaperone, PapD N-terminal domain M CELLULAR PROCESSES AND SIGNALING Cell wall/membrane/envelope biogenesis ACIAD3336 CDS -3 3238386 3238850 no conserved hypothetical protein; putative protein U 63.5 3NPQ4 Spore Coat Protein U domain S POORLY CHARACTERIZED Function unknown ACIAD3337 CDS -3 3239175 3240821 no pglL oligosaccharyltransferase 1051 3NIXG macromolecule glycosylation M CELLULAR PROCESSES AND SIGNALING Cell wall/membrane/envelope biogenesis ACIAD3338 CDS -2 3240883 3241326 no comP competence factor involved in DNA binding and uptake 263 3NPSI pilus assembly protein major pilin PilA N CELLULAR PROCESSES AND SIGNALING Cell motility ACIAD3338 CDS -2 3240883 3241326 no comP competence factor involved in DNA binding and uptake 263 3NPSI pilus assembly protein major pilin PilA U CELLULAR PROCESSES AND SIGNALING Intracellular trafficking, secretion, and vesicular transport ACIAD3339 CDS -1 3241694 3242725 no adhA alcohol dehydrogenase 692 3NM23 Alcohol dehydrogenase GroES-like domain S POORLY CHARACTERIZED Function unknown ACIAD3340 CDS +2 3243530 3244393 no putative Nitrilase/cyanide hydratase and apolipoprotein N-acyltransferase 578 3NPW3 Carbon-nitrogen hydrolase S POORLY CHARACTERIZED Function unknown ACIAD3341 CDS +1 3244453 3247242 no putative arginine/lysine/ornithine decarboxylase 1840 3NPB3 Orn/Lys/Arg decarboxylase, C-terminal domain E METABOLISM Amino acid transport and metabolism ACIAD3342 CDS +3 3247284 3248843 no conserved hypothetical protein; putative biotin carboxylase 1075 3NRAG Biotin carboxylase I METABOLISM Lipid transport and metabolism ACIAD3343 CDS +3 3248853 3249875 no conserved hypothetical protein 706 3NR56 Acyl-coenzyme A:6-aminopenicillanic acid acyl-transferase S POORLY CHARACTERIZED Function unknown ACIAD3344 CDS -2 3249925 3250485 no conserved hypothetical protein 377 3NJKR TPM domain S POORLY CHARACTERIZED Function unknown ACIAD3345 CDS -3 3250479 3251528 no conserved hypothetical protein; putative membrane protein 567 3NKRQ TPM domain S POORLY CHARACTERIZED Function unknown ACIAD3347 CDS -3 3251571 3252161 no conserved hypothetical protein; putative signal peptide 377 3NK77 LemA family S POORLY CHARACTERIZED Function unknown ACIAD3348 CDS -2 3252295 3253185 no conserved hypothetical protein 599 3NSPN Predicted metal-dependent hydrolase S POORLY CHARACTERIZED Function unknown ACIAD3349 CDS -3 3253359 3254780 no gltD glutamate synthase small chain 974 3NIS3 glutamate synthase E METABOLISM Amino acid transport and metabolism ACIAD3350 CDS -1 3254855 3259336 no gltB glutamate synthase large chain precursor 2924 3NJ2V Glutamate synthase central domain E METABOLISM Amino acid transport and metabolism ACIAD3352 CDS -2 3259789 3260640 no conserved hypothetical protein; putative signal peptide 526 3NIM6 S POORLY CHARACTERIZED Function unknown ACIAD3353 CDS -2 3260650 3261738 no aroB 3-dehydroquinate synthase 719 3NKDH Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ) E METABOLISM Amino acid transport and metabolism ACIAD3354 CDS -2 3261760 3262302 no aroK shikimate-kinase 353 3NJ5H Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate F METABOLISM Nucleotide transport and metabolism ACIAD3355 CDS -2 3262339 3264510 no ComQ outer membrane protein ComQ/PilQ 1368 3NIVQ Secretin and TonB N terminus short domain U CELLULAR PROCESSES AND SIGNALING Intracellular trafficking, secretion, and vesicular transport ACIAD3356 CDS -3 3264528 3265052 no pilP type IV pilus assembly protein PilP 345 3NJEN Pilus assembly protein, PilP N CELLULAR PROCESSES AND SIGNALING Cell motility ACIAD3356 CDS -3 3264528 3265052 no pilP type IV pilus assembly protein PilP 345 3NJEN Pilus assembly protein, PilP U CELLULAR PROCESSES AND SIGNALING Intracellular trafficking, secretion, and vesicular transport ACIAD3357 CDS -1 3265052 3265789 no putative membrane protein (ComO) 471 3NJ8W Pilus assembly protein, PilO N CELLULAR PROCESSES AND SIGNALING Cell motility ACIAD3357 CDS -1 3265052 3265789 no putative membrane protein (ComO) 471 3NJ8W Pilus assembly protein, PilO U CELLULAR PROCESSES AND SIGNALING Intracellular trafficking, secretion, and vesicular transport ACIAD3359 CDS -2 3265786 3266424 no putative membrane protein (ComN) 414 3NIH9 Fimbrial assembly protein (PilN) N CELLULAR PROCESSES AND SIGNALING Cell motility ACIAD3359 CDS -2 3265786 3266424 no putative membrane protein (ComN) 414 3NIH9 Fimbrial assembly protein (PilN) U CELLULAR PROCESSES AND SIGNALING Intracellular trafficking, secretion, and vesicular transport ACIAD3360 CDS -3 3266421 3267446 no putative membrane protein (ComM) 646 3NKVX Type IV pilus assembly protein PilM; N CELLULAR PROCESSES AND SIGNALING Cell motility ACIAD3360 CDS -3 3266421 3267446 no putative membrane protein (ComM) 646 3NKVX Type IV pilus assembly protein PilM; U CELLULAR PROCESSES AND SIGNALING Intracellular trafficking, secretion, and vesicular transport ACIAD3361 CDS +3 3267648 3270206 no mrcA penicillin binding protein 1650 3NJYW penicillin-binding protein M CELLULAR PROCESSES AND SIGNALING Cell wall/membrane/envelope biogenesis ACIAD3362 CDS -3 3270219 3271040 no rrm 23S ribosomal RNA G745 methyltransferase 550 3NIHV Methyltransferase domain Q METABOLISM Secondary metabolites biosynthesis, transport and catabolism ACIAD3363 CDS -1 3271106 3272224 no mraY phospho-N-acetylmuramoyl-pentapeptide transferase 717 3NJV1 First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan M CELLULAR PROCESSES AND SIGNALING Cell wall/membrane/envelope biogenesis ACIAD3364 CDS -1 3272225 3273631 no murF UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase (UDP-MurNAc-pentapeptide synthetase) (D-alanyl-D- alanine-adding enzyme) 914 3NJ67 Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein M CELLULAR PROCESSES AND SIGNALING Cell wall/membrane/envelope biogenesis ACIAD3365 CDS -2 3273640 3275139 no murE UDP-N-acetylmuramoylalanyl-D-glutamate-2, 6-diaminopimelate ligase 988 3NKQI Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan M CELLULAR PROCESSES AND SIGNALING Cell wall/membrane/envelope biogenesis ACIAD3366 CDS -1 3275147 3277012 no ftsI septum formation, penicillin binding protein 3, peptidoglycan synthetase 1208 3NIFN Catalyzes cross-linking of the peptidoglycan cell wall at the division septum M CELLULAR PROCESSES AND SIGNALING Cell wall/membrane/envelope biogenesis ACIAD3367 CDS -3 3276996 3277328 no ftsL cell division protein (in growth at septum) 213 3NNWJ Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic D CELLULAR PROCESSES AND SIGNALING Cell cycle control, cell division, chromosome partitioning ACIAD3368 CDS -3 3277338 3278249 no mraW Ribosomal RNA small subunit methyltransferase H 583 3NIS5 Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA J INFORMATION STORAGE AND PROCESSING Translation, ribosomal structure and biogenesis ACIAD3369 CDS -1 3278627 3279628 no sbp sulfate transport protein (ABC superfamily, peri_bind) 679 3NIR3 sulfate ABC transporter P METABOLISM Inorganic ion transport and metabolism ACIAD3370 CDS +1 3280003 3280305 no conserved hypothetical protein; putative signal peptide 189 3NNWW S POORLY CHARACTERIZED Function unknown ACIAD3371 CDS +2 3280430 3281938 no gltX glutamyl-tRNA synthetase 1026 3NKI0 Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu) J INFORMATION STORAGE AND PROCESSING Translation, ribosomal structure and biogenesis ACIAD3373 CDS +2 3282266 3282607 no conserved hypothetical protein; putative membrane protein 177 3NP1H S POORLY CHARACTERIZED Function unknown ACIAD3374 CDS -1 3282644 3283567 no czcD cation efflux system protein 571 3NK3D Cation efflux family P METABOLISM Inorganic ion transport and metabolism ACIAD3375 CDS -1 3283679 3286870 no czcA RND divalent metal cation efflux transporter 1998 3NJFS Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family P METABOLISM Inorganic ion transport and metabolism ACIAD3376 CDS -3 3286833 3288086 no czcB RND divalent metal cation efflux membrane fusion protein 763 3NK1H Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family M CELLULAR PROCESSES AND SIGNALING Cell wall/membrane/envelope biogenesis ACIAD3378 CDS -1 3288086 3289489 no czcC outer membrane protein precursor 832 3NJYG Outer membrane efflux protein M CELLULAR PROCESSES AND SIGNALING Cell wall/membrane/envelope biogenesis ACIAD3378 CDS -1 3288086 3289489 no czcC outer membrane protein precursor 832 3NJYG Outer membrane efflux protein U CELLULAR PROCESSES AND SIGNALING Intracellular trafficking, secretion, and vesicular transport ACIAD3379 CDS -3 3289536 3289925 no czcI cation efflux system protein 265 3NP9E S POORLY CHARACTERIZED Function unknown ACIAD3380 CDS -1 3290054 3291715 no putative transport protein (ABC superfamily, atp_bind) 1078 3NII1 COG0488 ATPase components of ABC transporters with duplicated ATPase domains S POORLY CHARACTERIZED Function unknown ACIAD3381 CDS -3 3291936 3293657 no poxB pyruvate dehydrogenase (quinone) 1149 3NKH8 Thiamine pyrophosphate enzyme, central domain C METABOLISM Energy production and conversion ACIAD3382 CDS +3 3293919 3295202 no metY homocysteine synthase 788 3NK4W Cys/Met metabolism PLP-dependent enzyme E METABOLISM Amino acid transport and metabolism ACIAD3383 CDS +1 3295450 3296361 no acr1 fatty acyl-CoA reductase (hexadecanal dehydrogenase,acylating) 575 3NJ1A Belongs to the short-chain dehydrogenases reductases (SDR) family S POORLY CHARACTERIZED Function unknown ACIAD3384 CDS -3 3296424 3298622 no putative sulfate permease 1332 3NKQV Carbonic anhydrase P METABOLISM Inorganic ion transport and metabolism ACIAD3386 CDS -2 3298894 3301284 no putative transcriptional accessory protein 1480 3NJ56 Tex-like protein N-terminal domain K INFORMATION STORAGE AND PROCESSING Transcription ACIAD3388 CDS +2 3301865 3302629 no ompR two-component response regulator 496 3NIN8 COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain K INFORMATION STORAGE AND PROCESSING Transcription ACIAD3389 CDS +2 3302651 3304108 no envZ sensory histidine kinase in two-component regulatory system with OmpR 962 3NKUF Histidine kinase T CELLULAR PROCESSES AND SIGNALING Signal transduction mechanisms ACIAD3390 CDS +1 3304318 3305832 no putative acetyl-CoA hydrolase/transferase 984 3NMFK acetyl-CoA hydrolase C METABOLISM Energy production and conversion ACIAD3391 CDS +2 3305963 3306382 no putative acyltransferase 289 3NNAC FR47-like protein K INFORMATION STORAGE AND PROCESSING Transcription ACIAD3392 CDS -3 3306390 3307652 no putative long-chain fatty acid transport protein 854 3NK4V Outer membrane protein transport protein (OMPP1/FadL/TodX) I METABOLISM Lipid transport and metabolism ACIAD3393 CDS -2 3307777 3308508 no putative SAM-dependent methyltransferase 500 3NT3P Methyltransferase domain Q METABOLISM Secondary metabolites biosynthesis, transport and catabolism ACIAD3394 CDS -1 3309014 3309397 no conserved hypothetical protein 259 3NN7A Acetyltransferase (GNAT) domain K INFORMATION STORAGE AND PROCESSING Transcription ACIAD3395 CDS +3 3309483 3310091 no hisB imidazoleglycerol-phosphate dehydratase 402 3NK7V imidazoleglycerol-phosphate dehydratase E METABOLISM Amino acid transport and metabolism ACIAD3396 CDS +2 3310094 3310711 no hisH imidazole glycerol phosphate synthetase, glutamine amidotransferase subunit 432 3NITT IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR E METABOLISM Amino acid transport and metabolism ACIAD3397 CDS +3 3310863 3311432 no conserved hypothetical protein; putative membrane protein 368 3NM1Y Protein of unknown function (DUF805) S POORLY CHARACTERIZED Function unknown ACIAD3398 CDS +3 3311544 3312275 no hisA phosphoribosylformimino-5-aminoimidazole carboxamide isomerase 479 3NK1S 1-(5-phosphoribosyl)-5- (5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase E METABOLISM Amino acid transport and metabolism ACIAD3399 CDS -2 3312334 3316326 no putative peptide synthetase 2630 3NKRV AMP-binding enzyme Q METABOLISM Secondary metabolites biosynthesis, transport and catabolism ACIAD3400 CDS -3 3316677 3318398 no putative transport protein (ABC superfamily, atp_bind) 1062 3NJEA ABC transporter transmembrane region P METABOLISM Inorganic ion transport and metabolism ACIAD3401 CDS -2 3318556 3318951 no putative transmembrane protein 258 3NN4N membrane S POORLY CHARACTERIZED Function unknown ACIAD3402 CDS -1 3318989 3319615 no putative cold shock protein 420 3NJVM Protein of unknown function (DUF1294) K INFORMATION STORAGE AND PROCESSING Transcription ACIAD3403 CDS -1 3319628 3320626 no putative homoserine kinase (ThrB) 652 3NJ98 Belongs to the pseudomonas-type ThrB family F METABOLISM Nucleotide transport and metabolism ACIAD3404 CDS +1 3320641 3321450 no hisF imidazole glycerol phosphate synthase, cyclase subunit 527 3NIUS IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit E METABOLISM Amino acid transport and metabolism ACIAD3405 CDS -3 3321561 3322202 no conserved hypothetical protein 447 3NIHH S POORLY CHARACTERIZED Function unknown ACIAD3406 CDS +2 3322298 3323308 no conserved hypothetical protein; putative transcriptional regulator (AraC family) 666 3NJY0 helix_turn_helix, arabinose operon control protein K INFORMATION STORAGE AND PROCESSING Transcription ACIAD3407 CDS -2 3323323 3323574 no conserved hypothetical protein 164 3NPCN S POORLY CHARACTERIZED Function unknown ACIAD3408 CDS -1 3323651 3324727 no putative DNA/RNA non-specific endonuclease G protein 702 3NKFZ DNA RNA non-specific endonuclease F METABOLISM Nucleotide transport and metabolism ACIAD3411 CDS +1 3324985 3325380 no conserved hypothetical protein; putative signal peptide 196 3NPWH S POORLY CHARACTERIZED Function unknown ACIAD3412 CDS -2 3325456 3327336 no trkD potassium transport system, low affinity (KUP family) 1221 3NJGS Transport of potassium into the cell P METABOLISM Inorganic ion transport and metabolism ACIAD3414 CDS +3 3327660 3327989 no putative integrase 87.8 3NSY9 Arm DNA-binding domain L INFORMATION STORAGE AND PROCESSING Replication, recombination and repair ACIAD3415 CDS -1 3328178 3328456 no hypothetical protein 196 3NPTJ S POORLY CHARACTERIZED Function unknown ACIAD3418 CDS +1 3328885 3329118 no hypothetical protein; putative conserved domain 150 COG3177 Filamentation induced by cAMP protein fic D CELLULAR PROCESSES AND SIGNALING Cell cycle control, cell division, chromosome partitioning ACIAD3418 CDS +1 3328885 3329118 no hypothetical protein; putative conserved domain 150 COG3177 Filamentation induced by cAMP protein fic D CELLULAR PROCESSES AND SIGNALING Cell cycle control, cell division, chromosome partitioning ACIAD3419 CDS +2 3329180 3329746 no hypothetical protein 111 3NPKX S POORLY CHARACTERIZED Function unknown ACIAD3421 CDS -1 3330230 3331675 no putative outer membrane protein precursor 850 3NJKG Outer membrane efflux protein M CELLULAR PROCESSES AND SIGNALING Cell wall/membrane/envelope biogenesis ACIAD3421 CDS -1 3330230 3331675 no putative outer membrane protein precursor 850 3NJKG Outer membrane efflux protein U CELLULAR PROCESSES AND SIGNALING Intracellular trafficking, secretion, and vesicular transport ACIAD3422 CDS -1 3331691 3334867 no mdtC multidrug transport protein, outer membrane (RND family) 1932 3NJS6 Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family V CELLULAR PROCESSES AND SIGNALING Defense mechanisms ACIAD3423 CDS -2 3334864 3338025 no mdtB multidrug transport protein (RND family) 1932 3NJS6 Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family V CELLULAR PROCESSES AND SIGNALING Defense mechanisms ACIAD3424 CDS -2 3338035 3339333 no mdtA membrane protein inolved in drug resistance 823 3NJIY Barrel-sandwich domain of CusB or HlyD membrane-fusion M CELLULAR PROCESSES AND SIGNALING Cell wall/membrane/envelope biogenesis ACIAD3425 CDS -1 3339596 3341326 no conserved hypothetical protein 1146 3NKU1 acetyltransferases and hydrolases with the alpha beta hydrolase fold S POORLY CHARACTERIZED Function unknown ACIAD3426 CDS -3 3341328 3342386 no putative cognate immunity protein 701 3NK9E S POORLY CHARACTERIZED Function unknown ACIAD3427 CDS -1 3342407 3345145 no putative VGR-related protein 1736 3NIE7 Phage late control gene D protein (GPD) S POORLY CHARACTERIZED Function unknown ACIAD3428 CDS -3 3345333 3345845 no conserved hypothetical protein 352 COG1487 nuclease activity S POORLY CHARACTERIZED Function unknown ACIAD3428 CDS -3 3345333 3345845 no conserved hypothetical protein 352 COG1487 nuclease activity S POORLY CHARACTERIZED Function unknown ACIAD3429 CDS -2 3345832 3346944 no putative peptidase_M78 domain-containing protein 716 1RR40 IrrE N-terminal-like domain E METABOLISM Amino acid transport and metabolism ACIAD3430 CDS -2 3347071 3350133 no putative type I restriction-modification system (HsdR) 2010 3NJIW Type I restriction enzyme R protein N terminus (HSDR_N) L INFORMATION STORAGE AND PROCESSING Replication, recombination and repair ACIAD3431 CDS -3 3350154 3351500 no putative type I restriction-modification system specificity determinant for hsdM and hsdR (HsdS) 872 3NN5F Type I restriction modification DNA specificity domain V CELLULAR PROCESSES AND SIGNALING Defense mechanisms ACIAD3432 CDS -1 3351497 3353752 no putative type I restriction-modification system DNA methylase (HsdM) 1488 3NMFA N-6 DNA Methylase V CELLULAR PROCESSES AND SIGNALING Defense mechanisms ACIAD3434 CDS -1 3353762 3354355 no putative restriction modification system DNA specificity 377 1SQWA Type I restriction modification DNA specificity domain V CELLULAR PROCESSES AND SIGNALING Defense mechanisms ACIAD3436 CDS -3 3354594 3356537 no DUF262 domain-containing protein 1301 3NM3D Protein of unknown function DUF262 S POORLY CHARACTERIZED Function unknown ACIAD3437 CDS -3 3356670 3357605 no DUF4357 domain-containing protein 623 3NM7Z Domain of unknown function (DUF4357) L INFORMATION STORAGE AND PROCESSING Replication, recombination and repair ACIAD3440 CDS +3 3358362 3359021 no putative DUF4357 domain-containing protein 444 3NN5I Protein of unknown function (DUF805) S POORLY CHARACTERIZED Function unknown ACIAD3441 CDS -1 3359090 3360931 no kef glutathione-regulated potassium-efflux system protein (K(+)/H(+) antiporter) 1129 3NKJE Belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family P METABOLISM Inorganic ion transport and metabolism ACIAD3442 CDS -2 3361213 3362031 no putative methyltransferase 558 3NJ7G Mycolic acid cyclopropane synthetase M CELLULAR PROCESSES AND SIGNALING Cell wall/membrane/envelope biogenesis ACIAD3443 CDS -2 3362059 3363405 no conserved hypothetical protein 909 3NK9C Flavin containing amine oxidoreductase S POORLY CHARACTERIZED Function unknown ACIAD3444 CDS -3 3363798 3364751 no conserved hypothetical protein; putative pirin-like protein 642 3NISY Belongs to the pirin family S POORLY CHARACTERIZED Function unknown ACIAD3445 CDS -2 3364855 3366303 no gabD NADP+ -dependent succinate semialdehyde dehydrogenase 935 3NIN2 Involved in the biosynthesis of the osmoprotectant glycine betaine. Catalyzes the reversible oxidation of betaine aldehyde to the corresponding acid C METABOLISM Energy production and conversion ACIAD3446 CDS -3 3366309 3367595 no gabT 4-aminobutyrate aminotransferase, PLP-dependent 847 3NJXN Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family E METABOLISM Amino acid transport and metabolism ACIAD3447 CDS +2 3367748 3369247 no putative transcriptional regulator (GntR family) 1010 3NIFY helix_turn_helix gluconate operon transcriptional repressor K INFORMATION STORAGE AND PROCESSING Transcription ACIAD3448 CDS -1 3369317 3370756 no gabP gamma-aminobutyrate permease 940 3NSN1 Amino acid permease E METABOLISM Amino acid transport and metabolism ACIAD3449 CDS -3 3371292 3371870 no ssb ssDNA-binding protein controls activity of RecBCD nuclease 343 3NJSD Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism L INFORMATION STORAGE AND PROCESSING Replication, recombination and repair ACIAD3450 CDS -2 3371923 3373287 no putative transport protein (MFS superfamily) 820 3NJ46 Sugar (and other) transporter E METABOLISM Amino acid transport and metabolism ACIAD3450 CDS -2 3371923 3373287 no putative transport protein (MFS superfamily) 820 3NJ46 Sugar (and other) transporter G METABOLISM Carbohydrate transport and metabolism ACIAD3450 CDS -2 3371923 3373287 no putative transport protein (MFS superfamily) 820 3NJ46 Sugar (and other) transporter P METABOLISM Inorganic ion transport and metabolism ACIAD3451 CDS -3 3373425 3374507 no putative integral membrane protein 690 3NIFU Protein of unknown function (DUF475) S POORLY CHARACTERIZED Function unknown ACIAD3452 CDS +3 3374703 3375374 no putative transcriptional activator (TenA family) 457 3NIGU Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway K INFORMATION STORAGE AND PROCESSING Transcription ACIAD3453 CDS -1 3375479 3375823 no glpM membrane protein required for efficient alginate biosynthesis 221 3NNYE GlpM protein S POORLY CHARACTERIZED Function unknown ACIAD3454 CDS +1 3375946 3376383 no hypothetical protein 293 3NP77 S POORLY CHARACTERIZED Function unknown ACIAD3455 CDS +3 3376566 3379463 no uvrA excinuclease ABC subunit A 1911 3NK1U The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate L INFORMATION STORAGE AND PROCESSING Replication, recombination and repair ACIAD3456 CDS +2 3379496 3380782 no hypothetical protein 847 1S7HM SEC-C Motif Domain Protein S POORLY CHARACTERIZED Function unknown ACIAD3457 CDS -2 3380833 3382575 no putative GGDEF family protein 1090 3NJKH diguanylate cyclase T CELLULAR PROCESSES AND SIGNALING Signal transduction mechanisms ACIAD3459 CDS +1 3383572 3384495 no omp33 34 kDa outer membrane protein 572 3NKXV Putative general bacterial porin S POORLY CHARACTERIZED Function unknown ACIAD3460 CDS -3 3384555 3386537 no glycine betaine transport protein 1281 3NIKZ Belongs to the BCCT transporter (TC 2.A.15) family M CELLULAR PROCESSES AND SIGNALING Cell wall/membrane/envelope biogenesis ACIAD3461 CDS -2 3386689 3387381 no putative transporter 432 3NKRR Ion channel S POORLY CHARACTERIZED Function unknown ACIAD3462 CDS +3 3387579 3387956 no hypothetical protein; putative signal peptide 251 3NPNG S POORLY CHARACTERIZED Function unknown ACIAD3463 CDS -3 3387996 3389732 no putative sodium:solute symporter 1095 3NJC9 Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family S POORLY CHARACTERIZED Function unknown ACIAD3464 CDS -2 3389713 3390045 no conserved hypothetical protein; putative membrane protein 212 3NNK6 Protein of unknown function, DUF485 S POORLY CHARACTERIZED Function unknown ACIAD3465 CDS +3 3390195 3393725 no putative two-component sensor 2307 3NISR PAS fold T CELLULAR PROCESSES AND SIGNALING Signal transduction mechanisms ACIAD3468 CDS +2 3394100 3394867 no conserved hypothetical protein 516 3NIRT S POORLY CHARACTERIZED Function unknown ACIAD3469 CDS -1 3394940 3395590 no putative two-component response regulator 421 3NJDD Sigma-70, region 4 K INFORMATION STORAGE AND PROCESSING Transcription ACIAD3470 CDS +1 3395965 3396699 no msuE NADH-dependent FMN reductase 473 3NIUH Flavodoxin-like fold S POORLY CHARACTERIZED Function unknown ACIAD3471 CDS +1 3396718 3397836 no putative sulfonate monooxygenase (MsuD) 743 3NJK1 Luciferase-like monooxygenase C METABOLISM Energy production and conversion ACIAD3472 CDS -1 3397928 3398335 no putative transcriptional regulator (Lrp-like) 268 3NN8C helix_turn_helix ASNC type K INFORMATION STORAGE AND PROCESSING Transcription ACIAD3473 CDS +3 3398433 3398972 no putative isochorismatase 352 3NT4E Isochorismatase family Q METABOLISM Secondary metabolites biosynthesis, transport and catabolism ACIAD3474 CDS -2 3398998 3400200 no putative FMNH2-dependent monooxygenase 798 3NT7V Acyl-CoA dehydrogenase, C-terminal domain I METABOLISM Lipid transport and metabolism ACIAD3475 CDS -2 3400318 3402279 no acs acetyl-CoA synthetase 1356 3NJI3 Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA I METABOLISM Lipid transport and metabolism ACIAD3476 CDS +3 3402570 3403154 no conserved hypothetical protein 395 3NNCX Protein of unknown function (DUF805) S POORLY CHARACTERIZED Function unknown ACIAD3477 CDS +2 3403247 3404230 no conserved hypothetical protein; putative membrane protein 612 3NJ9B Mechanosensitive ion channel M CELLULAR PROCESSES AND SIGNALING Cell wall/membrane/envelope biogenesis ACIAD3478 CDS -1 3404219 3404926 no conserved hypothetical protein 471 3NJIX Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit J INFORMATION STORAGE AND PROCESSING Translation, ribosomal structure and biogenesis ACIAD3479 CDS -2 3404923 3406206 no kdtA 3-deoxy-D-manno-2-octulosonate transferase 841 3NJGR 3-Deoxy-D-manno-octulosonic-acid transferase (kdotransferase) M CELLULAR PROCESSES AND SIGNALING Cell wall/membrane/envelope biogenesis ACIAD3481 CDS -3 3406776 3408050 no conserved hypothetical protein; putative flavoprotein involved in K+ transport 866 3NT7Y Flavin-binding monooxygenase-like P METABOLISM Inorganic ion transport and metabolism ACIAD3482 CDS -3 3408579 3409376 no conserved hypothetical protein 563 3NQMP Phytanoyl-CoA dioxygenase (PhyH) Q METABOLISM Secondary metabolites biosynthesis, transport and catabolism ACIAD3483 CDS -2 3409558 3410718 no hypothetical protein; putative conserved domain 788 3NM0Q hemolysin activation secretion protein U CELLULAR PROCESSES AND SIGNALING Intracellular trafficking, secretion, and vesicular transport ACIAD3484 CDS -1 3410786 3411661 no putative arginine/ornithine binding protein (ABC superfamily, peri_bind)(artI, aotJ) 574 3NJH2 Bacterial periplasmic substrate-binding proteins E METABOLISM Amino acid transport and metabolism ACIAD3484 CDS -1 3410786 3411661 no putative arginine/ornithine binding protein (ABC superfamily, peri_bind)(artI, aotJ) 574 3NJH2 Bacterial periplasmic substrate-binding proteins T CELLULAR PROCESSES AND SIGNALING Signal transduction mechanisms ACIAD3485 CDS +1 3411814 3412539 no conserved hypothetical protein; putative aldolase class II 481 3NKTR Class II Aldolase and Adducin N-terminal domain G METABOLISM Carbohydrate transport and metabolism ACIAD3486 CDS -3 3412617 3413486 no putative dioxygenase 594 3NMW4 Phytanoyl-CoA dioxygenase (PhyH) Q METABOLISM Secondary metabolites biosynthesis, transport and catabolism ACIAD3487 CDS -1 3413513 3414358 no putative amino acid binding protein (ABC superfamily, peri_bind) 552 3NM72 Belongs to the bacterial solute-binding protein 3 family E METABOLISM Amino acid transport and metabolism ACIAD3487 CDS -1 3413513 3414358 no putative amino acid binding protein (ABC superfamily, peri_bind) 552 3NM72 Belongs to the bacterial solute-binding protein 3 family T CELLULAR PROCESSES AND SIGNALING Signal transduction mechanisms ACIAD3488 CDS -2 3414553 3416070 no putative amino acid transport protein (ABC superfamily, ATP_bind and membrane) 963 3NMG7 Transporter P METABOLISM Inorganic ion transport and metabolism ACIAD3489 CDS -3 3416331 3417470 no argE N-acetylornithine deacetylase 758 3NM70 Belongs to the peptidase M20A family. ArgE subfamily E METABOLISM Amino acid transport and metabolism ACIAD3490 CDS -3 3417471 3418457 no putative transcriptional regulator 636 3NM34 Evidence 3 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology K INFORMATION STORAGE AND PROCESSING Transcription ACIAD3492 CDS -3 3418494 3419171 no conserved hypothetical protein 442 3NM6M Family of unknown function (DUF1028) S POORLY CHARACTERIZED Function unknown ACIAD3493 CDS -1 3419180 3419602 no conserved hypothetical protein 279 3NN62 Endoribonuclease L-PSP J INFORMATION STORAGE AND PROCESSING Translation, ribosomal structure and biogenesis ACIAD3496 CDS -3 3420162 3421232 no xenB xenobiotic reductase 708 3NKMZ NADH:flavin oxidoreductase / NADH oxidase family C METABOLISM Energy production and conversion ACIAD3497 CDS -3 3421254 3421559 no putative transcriptional regulator (ArsR family) 205 3NNWX Helix-turn-helix domain K INFORMATION STORAGE AND PROCESSING Transcription ACIAD3498 CDS -2 3421705 3422718 no prfB peptide chain release factor 2 613 3NIHM Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA J INFORMATION STORAGE AND PROCESSING Translation, ribosomal structure and biogenesis ACIAD3499 CDS +2 3423251 3424024 no conserved hypothetical protein; putative porin 523 3NIZG Putative general bacterial porin S POORLY CHARACTERIZED Function unknown ACIAD3500 CDS -2 3424072 3425778 no recJ ssDNA exonuclease, 5' --> 3' specific , Mg dependent 1130 3NK36 single-stranded-DNA-specific exonuclease RecJ L INFORMATION STORAGE AND PROCESSING Replication, recombination and repair ACIAD3501 CDS -2 3425779 3426435 no pdxH pyridoxamine 5'-phosphate oxidase (acts also on pyridoxine phosphate and pyridoxine) 456 3NJ7P Catalyzes the oxidation of either pyridoxine 5'- phosphate (PNP) or pyridoxamine 5'-phosphate (PMP) into pyridoxal 5'-phosphate (PLP) H METABOLISM Coenzyme transport and metabolism ACIAD3502 CDS -2 3426451 3427782 no glmM phosphoglucosamine mutase 873 3NKAA Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate G METABOLISM Carbohydrate transport and metabolism ACIAD3503 CDS -2 3427903 3429369 no guaB IMP dehydrogenase 926 3NJ7U Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth F METABOLISM Nucleotide transport and metabolism ACIAD3504 CDS -1 3429497 3430513 no putative membrane protein 620 3NJYK AI-2E family transporter S POORLY CHARACTERIZED Function unknown ACIAD3505 CDS -3 3430722 3431297 no putative membrane protein 365 3NK9S Uncharacterized protein family UPF0016 S POORLY CHARACTERIZED Function unknown ACIAD3506 CDS -1 3431636 3433621 no aceF dihydrolipoamide S-acetyltransferase, E2 component of the pyruvate dehydrogenase complex 1089 3NJS0 acetyltransferase component of pyruvate dehydrogenase complex C METABOLISM Energy production and conversion ACIAD3507 CDS -1 3433625 3436339 no aceE pyruvate decarboxylase, E1 component of the pyruvate dehydrogenase complex. 1838 3NKA2 Component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2) C METABOLISM Energy production and conversion ACIAD3508 CDS -3 3436608 3437333 no putative peptidase 479 3NKBI Peptidase family M23 M CELLULAR PROCESSES AND SIGNALING Cell wall/membrane/envelope biogenesis ACIAD3509 CDS +2 3437432 3437854 no conserved hypothetical protein 268 3NNIT Protein conserved in bacteria S POORLY CHARACTERIZED Function unknown ACIAD3510 CDS -1 3437951 3438853 no lpxC UDP-3-O-acyl-N-acetylglucosamine deacetylase 592 3NJID Catalyzes the hydrolysis of UDP-3-O-myristoyl-N- acetylglucosamine to form UDP-3-O-myristoylglucosamine and acetate, the committed step in lipid A biosynthesis M CELLULAR PROCESSES AND SIGNALING Cell wall/membrane/envelope biogenesis ACIAD3511 CDS -2 3438964 3440133 no ftsZ cell division protein,tubulin-like GTP-binding protein and GTPase, forms circumferential ring in cell division and participates in the septum formation 744 3NKHJ Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity D CELLULAR PROCESSES AND SIGNALING Cell cycle control, cell division, chromosome partitioning ACIAD3512 CDS -3 3440298 3441560 no ftsA cell division protein 809 3NJGA Cell division protein that is involved in the assembly of the Z ring. May serve as a membrane anchor for the Z ring D CELLULAR PROCESSES AND SIGNALING Cell cycle control, cell division, chromosome partitioning ACIAD3514 CDS -2 3441625 3442479 no ftsQ cell division protein (in growth of wall at septum) 563 3NT6F Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly D CELLULAR PROCESSES AND SIGNALING Cell cycle control, cell division, chromosome partitioning ACIAD3515 CDS -3 3442482 3443411 no ddlB D-alanine-D-alanine ligase B 614 3NJ01 Belongs to the D-alanine--D-alanine ligase family F METABOLISM Nucleotide transport and metabolism ACIAD3516 CDS -1 3443462 3444910 no murC UDP-N-acetylmuramate--alanine ligase 943 3NK5E Belongs to the MurCDEF family M CELLULAR PROCESSES AND SIGNALING Cell wall/membrane/envelope biogenesis ACIAD3517 CDS -3 3444924 3446021 no murG UDP-N-acetylglucosamine:N-acetylmuramyl-(pentapeptide) pyrophosphoryl-undecaprenol N-acetylglucosamine transferase 713 3NJ13 Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II) M CELLULAR PROCESSES AND SIGNALING Cell wall/membrane/envelope biogenesis ACIAD3518 CDS -3 3446262 3447206 no gshB glutathione synthetase 634 3NIX2 Belongs to the prokaryotic GSH synthase family H METABOLISM Coenzyme transport and metabolism ACIAD3520 CDS +1 3447844 3449541 no DUF4394 domain-containing protein 1044 1T1JN Domain of unknown function (DUF4394) S POORLY CHARACTERIZED Function unknown ACIAD3521 CDS +3 3449757 3450023 no conserved hypothetical protein 178 3NQ3G Domain of unknown function (DUF1737) S POORLY CHARACTERIZED Function unknown ACIAD3522 CDS -2 3450070 3450576 no putative flavoprotein oxidoreductase 326 3NITH Flavin reductase like domain S POORLY CHARACTERIZED Function unknown ACIAD3523 CDS -3 3450762 3451796 no metE 5-methyltetrahydropteroyltriglutamate- homocysteine methyltransferase 688 3NITP Cobalamin-independent synthase, Catalytic domain E METABOLISM Amino acid transport and metabolism ACIAD3524 CDS -1 3451814 3452881 no Protein of unknown function DUF1852 716 3NJEY Domain of unknown function (DUF1852) S POORLY CHARACTERIZED Function unknown ACIAD3525 CDS -1 3453068 3453781 no pyrE orotate phosphoribosyltransferase 458 3NK81 Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP) F METABOLISM Nucleotide transport and metabolism ACIAD3526 CDS +1 3453721 3454578 no crc catabolite repression control protein 604 3NJV4 Endonuclease/Exonuclease/phosphatase family L INFORMATION STORAGE AND PROCESSING Replication, recombination and repair ACIAD3528 CDS +1 3455050 3455400 no conserved hypothetical protein; putative arsenate reductase and related 232 3NNYU Belongs to the ArsC family P METABOLISM Inorganic ion transport and metabolism ACIAD3529 CDS -2 3455455 3455892 no conserved hypothetical protein 293 3NN63 Uncharacterized protein conserved in bacteria (DUF2147) S POORLY CHARACTERIZED Function unknown ACIAD3530 CDS +1 3456055 3456960 no est esterase precursor 595 3NKDS Steryl acetyl hydrolase I METABOLISM Lipid transport and metabolism ACIAD3531 CDS +1 3457081 3458262 no conserved hypothetical protein; putative conserved domain GGDEF 774 3NKZE diguanylate cyclase T CELLULAR PROCESSES AND SIGNALING Signal transduction mechanisms ACIAD3532 CDS -1 3458276 3460096 no dsbD thiol:disulfide interchange protein precursor 1171 3NJXZ Thiol disulfide interchange protein C METABOLISM Energy production and conversion ACIAD3532 CDS -1 3458276 3460096 no dsbD thiol:disulfide interchange protein precursor 1171 3NJXZ Thiol disulfide interchange protein O CELLULAR PROCESSES AND SIGNALING Posttranslational modification, protein turnover, chaperones ACIAD3533 CDS -2 3460117 3460899 no conserved hypothetical protein; putative signal peptide 516 3NJ9Y Putative MetA-pathway of phenol degradation S POORLY CHARACTERIZED Function unknown ACIAD3534 CDS -2 3460900 3461457 no conserved hypothetical protein 367 3NJ4Y response to abiotic stimulus S POORLY CHARACTERIZED Function unknown ACIAD3535 CDS -3 3461637 3461990 no conserved hypothetical protein 230 3NNXE Sigma 54 modulation protein / S30EA ribosomal protein J INFORMATION STORAGE AND PROCESSING Translation, ribosomal structure and biogenesis ACIAD3536 CDS +3 3462243 3463220 no puuE allantoinase 697 3NIEE Polysaccharide deacetylase G METABOLISM Carbohydrate transport and metabolism ACIAD3537 CDS +1 3463360 3463863 no pucL Uricase (Urate oxidase) 331 3NNE8 OHCU decarboxylase S POORLY CHARACTERIZED Function unknown ACIAD3538 CDS +3 3463860 3464183 no putative 5-hydroxyisourate hydrolase (HIU hydrolase) (HIUase) 219 3NPH8 Belongs to the transthyretin family. 5-hydroxyisourate hydrolase subfamily S POORLY CHARACTERIZED Function unknown ACIAD3539 CDS +2 3464261 3465097 no conserved hypothetical protein 580 3NJMX Nucleoside-specific channel-forming protein, Tsx M CELLULAR PROCESSES AND SIGNALING Cell wall/membrane/envelope biogenesis ACIAD3540 CDS -3 3465147 3466304 no hpxO FAD-dependent urate oxidase 770 3NK2I FAD binding domain C METABOLISM Energy production and conversion ACIAD3540 CDS -3 3465147 3466304 no hpxO FAD-dependent urate oxidase 770 3NK2I FAD binding domain H METABOLISM Coenzyme transport and metabolism ACIAD3541 CDS +1 3466513 3467517 no alc allantoicase 694 3NKYH Belongs to the allantoicase family F METABOLISM Nucleotide transport and metabolism ACIAD3542 CDS +1 3467533 3468042 no allA ureidoglycolate amidohydrolase 352 3NKSW Ureidoglycolate lyase F METABOLISM Nucleotide transport and metabolism ACIAD3543 CDS +1 3468148 3468921 no conserved hypothetical protein; putative exported protein 529 3NK2A S POORLY CHARACTERIZED Function unknown ACIAD3544 CDS -2 3468943 3470823 no parE topoisomerase IV subunit B 1239 3NJCN Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule L INFORMATION STORAGE AND PROCESSING Replication, recombination and repair ACIAD3545 CDS -2 3470839 3471432 no putative esterase 398 3NN3M Uncharacterised protein family (UPF0227) S POORLY CHARACTERIZED Function unknown ACIAD3547 CDS +1 3471622 3472986 no conserved hypothetical protein; putative enzyme 932 3NIIM PGAP1-like protein S POORLY CHARACTERIZED Function unknown ACIAD3548 CDS -1 3473090 3473605 no dsbB disulfide bond formation protein (Disulfide oxidoreductase) 348 3NNAP Required for disulfide bond formation in some periplasmic proteins. Acts by oxidizing the DsbA protein O CELLULAR PROCESSES AND SIGNALING Posttranslational modification, protein turnover, chaperones ACIAD3549 CDS -3 3473622 3475214 no gshA gamma-glutamate-cysteine ligase 1044 3NK8B Belongs to the glutamate--cysteine ligase type 1 family. Type 1 subfamily H METABOLISM Coenzyme transport and metabolism ACIAD3550 CDS +3 3475407 3475946 no conserved hypothetical protein 362 3NJPD Bacterial protein of unknown function (DUF924) S POORLY CHARACTERIZED Function unknown ACIAD3551 CDS +3 3475968 3476570 no conserved hypothetical protein; putative conserved domain 402 3NTV8 S POORLY CHARACTERIZED Function unknown ACIAD3552 CDS +2 3476588 3477895 no conserved hypothetical protein; putative membrane protein 844 3NJGI Protein of unknown function (DUF445) S POORLY CHARACTERIZED Function unknown ACIAD3553 CDS +3 3477927 3479081 no putative methionine aminotransferase, PLP-dependent 785 3NJU6 Cys/Met metabolism PLP-dependent enzyme E METABOLISM Amino acid transport and metabolism ACIAD3554 CDS +1 3479143 3480555 no putative transporter 870 3NKV4 MatE V CELLULAR PROCESSES AND SIGNALING Defense mechanisms ACIAD3555 CDS -3 3480612 3481448 no putative short-chain dehydrogenase 543 3NJJ0 Belongs to the short-chain dehydrogenases reductases (SDR) family S POORLY CHARACTERIZED Function unknown ACIAD3556 CDS +1 3481642 3482331 no putative transcriptional regulator (TetR family) 436 3NTA1 transcriptional regulator K INFORMATION STORAGE AND PROCESSING Transcription ACIAD3557 CDS +2 3482534 3483244 no phoB positive response regulator for the pho regulon, autophosphorylates and phosphorylates sensor PhoR 471 3NIRG phosphate regulon transcriptional regulatory protein PhoB K INFORMATION STORAGE AND PROCESSING Transcription ACIAD3558 CDS +2 3483248 3484612 no phoR two-component sensor 912 3NIYI Histidine kinase T CELLULAR PROCESSES AND SIGNALING Signal transduction mechanisms ACIAD3559 CDS +1 3484792 3485295 no conserved hypothetical protein; putative conserved domain 313 3NMPG S POORLY CHARACTERIZED Function unknown ACIAD3560 CDS -2 3485365 3486222 no psd phosphatidylserine decarboxylase 554 3NIG6 Belongs to the phosphatidylserine decarboxylase family. PSD-B subfamily. Prokaryotic type I sub-subfamily I METABOLISM Lipid transport and metabolism ACIAD3561 CDS -3 3486219 3487076 no rhdA thiosulfate sulfurtransferase (Rhodanese-like protein) 577 3NM01 Rhodanese Homology Domain P METABOLISM Inorganic ion transport and metabolism ACIAD3562 CDS -2 3487171 3488394 no pncB nicotinate phosphoribosyltransferase 815 3NIZE Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP F METABOLISM Nucleotide transport and metabolism ACIAD3563 CDS +1 3488548 3488988 no dtd D-tyrosyl tRNA(tyr) deacylase 289 3NN49 rejects L-amino acids rather than detecting D-amino acids in the active site. By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo and helps enforce protein L-homochirality J INFORMATION STORAGE AND PROCESSING Translation, ribosomal structure and biogenesis ACIAD3564 CDS -2 3489025 3489510 no conserved hypothetical protein 309 3NITM Membrane I METABOLISM Lipid transport and metabolism ACIAD3565 CDS -1 3489665 3490042 no conserved hypothetical protein; putative membrane protein 235 3NNNY S POORLY CHARACTERIZED Function unknown ACIAD3567 CDS -3 3490419 3491639 no serB phosphoserine phosphatase 771 3NJTN phosphoserine phosphatase E METABOLISM Amino acid transport and metabolism ACIAD3568 CDS +2 3491717 3493012 no conserved hypothetical protein 810 3NIPJ S POORLY CHARACTERIZED Function unknown ACIAD3570 CDS +3 3493308 3494429 no ribB/A bifunctional protein [Includes: 3,4-dihydroxy-2-butanone 4-phosphate synthase; GTP cyclohydrolase II] 738 3NJ8E Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate H METABOLISM Coenzyme transport and metabolism ACIAD3571 CDS +2 3494441 3494911 no ribH 6,7-dimethyl-8-ribityllumazine synthase (Lumazine synthase)(riboflavin synthase beta chain) 297 3NIEQ Catalyzes the formation of 6,7-dimethyl-8- ribityllumazine by condensation of 5-amino-6-(D- ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin H METABOLISM Coenzyme transport and metabolism ACIAD3572 CDS +2 3494915 3495364 no nusB transcription termination, L factor (N utilization substance protein B) 290 3NIY0 Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons K INFORMATION STORAGE AND PROCESSING Transcription ACIAD3573 CDS +1 3495379 3496296 no thiL thiamin-monophosphate kinase 612 3NKDN Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1 H METABOLISM Coenzyme transport and metabolism ACIAD3574 CDS +2 3496289 3496789 no pgpA phosphatidylglycerophosphatase A 348 3NN8J Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG) I METABOLISM Lipid transport and metabolism ACIAD3575 CDS +3 3496809 3498173 no glmU bifunctional protein [Includes: UDP-N-acetylglucosamine pyrophosphorylase (N-acetylglucosamine-1-phosphate uridyltransferase); Glucosamine-1-phosphate N-acetyltransferase ] 877 3NJT4 Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain M CELLULAR PROCESSES AND SIGNALING Cell wall/membrane/envelope biogenesis ACIAD3576 CDS +3 3498186 3500024 no glmS glucosamine--fructose-6-phosphate aminotransferase 1187 3NKBM Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source M CELLULAR PROCESSES AND SIGNALING Cell wall/membrane/envelope biogenesis ACIAD3577 fCDS +3 3500268 3500654 pseudo fragment of fumarylacetoacetase (Fumarylacetoacetate hydrolase) (HmgB) (part 1) 157 3NJYY Fumarylacetoacetase N-terminal Q METABOLISM Secondary metabolites biosynthesis, transport and catabolism ACIAD3578 fCDS +1 3500599 3501027 pseudo fragment of fumarylacetoacetase (Fumarylacetoacetate hydrolase) (HmgB) (part 2) 243 3NJYY Fumarylacetoacetase N-terminal Q METABOLISM Secondary metabolites biosynthesis, transport and catabolism ACIAD3579 CDS +2 3501035 3501343 partial fragment of putative homogentisate 1,2-dioxygenase 166 3NKC2 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily E METABOLISM Amino acid transport and metabolism ACIAD3581 CDS +3 3501453 3501740 no conserved hypothetical protein 196 3NTEK GCN5-related N-acetyl-transferase S POORLY CHARACTERIZED Function unknown ACIAD3582 CDS +2 3501743 3502228 no conserved hypothetical protein 322 3NP2T Protein of unknown function (DUF523) S POORLY CHARACTERIZED Function unknown ACIAD3583 CDS -2 3502201 3503202 no putative transporter; putative sodium/bile acid transporter family protein 610 3NJUI SBF-like CPA transporter family (DUF4137) S POORLY CHARACTERIZED Function unknown ACIAD3584 CDS -2 3503224 3503868 no pncA bifunctional protein [Includes: pyrazinamidase (PZAase); nicotinamidase (Nicotine deamidase)] 443 3NJB5 Isochorismatase family Q METABOLISM Secondary metabolites biosynthesis, transport and catabolism ACIAD3585 CDS +2 3504203 3505165 no dapA 4-hydroxy-tetrahydrodipicolinate synthase 634 3NK9V Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA) E METABOLISM Amino acid transport and metabolism ACIAD3586 CDS +2 3505175 3505780 no putative lipoprotein-34 precursor (NlpB) 391 3NJK7 Gram-negative-bacterium-type cell outer membrane assembly M CELLULAR PROCESSES AND SIGNALING Cell wall/membrane/envelope biogenesis ACIAD3587 CDS +3 3505818 3506537 no purC phosphoribosylaminoimidazole-succinocarboxamide synthase 479 3NJE6 Belongs to the SAICAR synthetase family F METABOLISM Nucleotide transport and metabolism ACIAD3588 CDS +2 3506930 3507847 no putative amino acid-binding protein (ABC superfamily, peri_bind) 577 3NMNW Belongs to the bacterial solute-binding protein 3 family E METABOLISM Amino acid transport and metabolism ACIAD3588 CDS +2 3506930 3507847 no putative amino acid-binding protein (ABC superfamily, peri_bind) 577 3NMNW Belongs to the bacterial solute-binding protein 3 family T CELLULAR PROCESSES AND SIGNALING Signal transduction mechanisms ACIAD3589 CDS +3 3507882 3508550 no putative amino acid transport protein (ABC superfamily, membrane) (gluP) 418 3NSMQ Binding-protein-dependent transport system inner membrane component P METABOLISM Inorganic ion transport and metabolism ACIAD3591 CDS +2 3508550 3509215 no putative amino acid transport protein (ABC superfamily, membrane) 414 3NSMR Binding-protein-dependent transport system inner membrane component P METABOLISM Inorganic ion transport and metabolism ACIAD3592 CDS +3 3509193 3509924 no putative amino acid transport protein (ABC superfamily, ATP_bind) 461 3NTMY ATPases associated with a variety of cellular activities E METABOLISM Amino acid transport and metabolism ACIAD3593 CDS +1 3510154 3511008 no conserved hypothetical protein; putative membrane protein 537 3NPZ9 Formate/nitrite transporter P METABOLISM Inorganic ion transport and metabolism ACIAD3594 CDS -2 3511012 3513042 no conserved hypothetical protein; putative diguanylate cyclase/phosphodiesterase 1347 3NJ45 Putative diguanylate phosphodiesterase T CELLULAR PROCESSES AND SIGNALING Signal transduction mechanisms ACIAD3596 CDS -1 3513635 3514906 no putative ATPase 828 3NJIQ COG2256 ATPase related to the helicase subunit of the Holliday junction resolvase L INFORMATION STORAGE AND PROCESSING Replication, recombination and repair ACIAD3597 CDS -3 3514986 3516179 no ampC beta-lactamase class C 789 3NIUE Beta-lactamase V CELLULAR PROCESSES AND SIGNALING Defense mechanisms ACIAD3598 CDS -1 3516197 3517369 no putative PQQ-dependent aldose sugar dehydrogenase precursor 795 3NJS3 Glucose / Sorbosone dehydrogenase G METABOLISM Carbohydrate transport and metabolism ACIAD3599 CDS -3 3517500 3518018 no putative transcriptional regulator; putative detoxification transcriptional regulator 337 3NN7H helix_turn_helix, mercury resistance K INFORMATION STORAGE AND PROCESSING Transcription ACIAD3600 CDS +2 3517967 3518611 no Cation efflux system protein 429 3NKK8 Cation efflux family P METABOLISM Inorganic ion transport and metabolism ACIAD3601 CDS -2 3518608 3519090 no conserved hypothetical protein 347 3NN2W Belongs to the UPF0260 family S POORLY CHARACTERIZED Function unknown ACIAD3602 CDS +2 3519248 3519406 no conserved hypothetical protein ; putative menbrane protein 90.9 3NPTS UPF0391 membrane protein S POORLY CHARACTERIZED Function unknown ACIAD3603 CDS +3 3519576 3520340 no putative dienelactone hydrolase 499 3NJXM dienelactone hydrolase Q METABOLISM Secondary metabolites biosynthesis, transport and catabolism ACIAD3604 CDS +2 3520394 3520762 no putative histidine triad family protein 256 3NNPS Protein similar to CwfJ C-terminus 1 F METABOLISM Nucleotide transport and metabolism ACIAD3604 CDS +2 3520394 3520762 no putative histidine triad family protein 256 3NNPS Protein similar to CwfJ C-terminus 1 G METABOLISM Carbohydrate transport and metabolism ACIAD3606 CDS +3 3520893 3521927 no mutY A/G specific adenine glycosylase 715 3NJ2N A G-specific L INFORMATION STORAGE AND PROCESSING Replication, recombination and repair ACIAD3607 CDS +2 3521939 3522499 no putative peptidase 386 3NKAS Peptidase family M23 M CELLULAR PROCESSES AND SIGNALING Cell wall/membrane/envelope biogenesis ACIAD3608 CDS +1 3522511 3522756 no conserved hypothetical protein 170 3NPCC S POORLY CHARACTERIZED Function unknown ACIAD3609 CDS -3 3522753 3523091 no hypothetical protein 237 COG0346 lactoylglutathione lyase activity E METABOLISM Amino acid transport and metabolism ACIAD3609 CDS -3 3522753 3523091 no hypothetical protein 237 COG0346 lactoylglutathione lyase activity E METABOLISM Amino acid transport and metabolism ACIAD3611 CDS +2 3523373 3523930 no tag 3-methyl-adenine DNA glycosylase I, constitutive 392 3NJYJ Methyladenine glycosylase L INFORMATION STORAGE AND PROCESSING Replication, recombination and repair ACIAD3612 CDS +2 3523955 3524977 no alrA NADP-dependent alcohol dehydrogenase 690 3NJRZ Alcohol dehydrogenase GroES-like domain S POORLY CHARACTERIZED Function unknown ACIAD3613 CDS -1 3525020 3526432 no putative transcriptional regulator 952 3NJ8S helix_turn_helix gluconate operon transcriptional repressor K INFORMATION STORAGE AND PROCESSING Transcription ACIAD3614 CDS +2 3526523 3526861 no conserved hypothetical protein; putative signal peptide 111 3NNKX S POORLY CHARACTERIZED Function unknown ACIAD3615 CDS -1 3526856 3527764 no putative transcriptional regulator; putative transcriptional activator 580 3NKDK LysR substrate binding domain K INFORMATION STORAGE AND PROCESSING Transcription ACIAD3616 CDS +1 3527908 3528714 no alrA aldehyde reductase 515 3NJFD Aldo/keto reductase family S POORLY CHARACTERIZED Function unknown ACIAD3617 CDS +3 3528726 3529901 no putative transport protein (MFS superfamily) 741 3NIRP Major Facilitator Superfamily E METABOLISM Amino acid transport and metabolism ACIAD3617 CDS +3 3528726 3529901 no putative transport protein (MFS superfamily) 741 3NIRP Major Facilitator Superfamily G METABOLISM Carbohydrate transport and metabolism ACIAD3617 CDS +3 3528726 3529901 no putative transport protein (MFS superfamily) 741 3NIRP Major Facilitator Superfamily P METABOLISM Inorganic ion transport and metabolism ACIAD3618 CDS -3 3529944 3530600 no conserved hypothetical protein; putative signal peptide 429 3NK63 START domain S POORLY CHARACTERIZED Function unknown ACIAD3619 CDS -1 3530801 3531622 no dapB 4-hydroxy-tetrahydrodipicolinate reductase 530 3NIYU Catalyzes the conversion of 4-hydroxy- tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate E METABOLISM Amino acid transport and metabolism ACIAD3621 CDS -2 3531742 3532848 no dnaJ heat shock protein (Hsp40), co-chaperone with DnaK 694 3NIEF ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins O CELLULAR PROCESSES AND SIGNALING Posttranslational modification, protein turnover, chaperones ACIAD3622 CDS -3 3532953 3533330 no conserved hypothetical protein; putative membrane protein 234 3NNJW S POORLY CHARACTERIZED Function unknown ACIAD3624 CDS -3 3533463 3536591 no putative efflux transporter causing drug resistance (Acr family) 1985 3NIN1 Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family V CELLULAR PROCESSES AND SIGNALING Defense mechanisms ACIAD3625 CDS -1 3536588 3537697 no putative RND efflux membrane fusion protein precursor 686 3NIFF Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family M CELLULAR PROCESSES AND SIGNALING Cell wall/membrane/envelope biogenesis ACIAD3626 CDS +2 3537851 3538465 no putative transcriptional regulator 407 3NJ2F Bacterial regulatory proteins, tetR family K INFORMATION STORAGE AND PROCESSING Transcription ACIAD3627 CDS +2 3538637 3541321 no ppc phosphoenolpyruvate carboxylase 1764 3NJ42 Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle H METABOLISM Coenzyme transport and metabolism ACIAD3628 CDS +1 3541600 3542895 no putative uracil transport protein (NCS2 family) 812 3NJBQ Permease family F METABOLISM Nucleotide transport and metabolism ACIAD3629 CDS +3 3543012 3543917 no putative transcriptional regulator 583 3NK0Y LysR substrate binding domain K INFORMATION STORAGE AND PROCESSING Transcription ACIAD3630 CDS -1 3543914 3544675 no conserved hypothetical protein; putative membrane protein 486 3NKEH membrane transporter protein S POORLY CHARACTERIZED Function unknown ACIAD3633 CDS -2 3544852 3546183 no ndh NADH dehydrogenase II 875 3NSYJ Pyridine nucleotide-disulphide oxidoreductase C METABOLISM Energy production and conversion ACIAD3635 CDS -3 3546405 3547706 no conserved hypothetical protein 876 3NIM3 S POORLY CHARACTERIZED Function unknown ACIAD3636 CDS -1 3547778 3549463 no putative dihydroxyacid dehydratase (ilvD-like) 1095 3NJMA Belongs to the IlvD Edd family E METABOLISM Amino acid transport and metabolism ACIAD3636 CDS -1 3547778 3549463 no putative dihydroxyacid dehydratase (ilvD-like) 1095 3NJMA Belongs to the IlvD Edd family G METABOLISM Carbohydrate transport and metabolism ACIAD3637 CDS +3 3549771 3550730 no fmt methionyl-tRNA formyltransferase 628 3NJJR Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus J INFORMATION STORAGE AND PROCESSING Translation, ribosomal structure and biogenesis ACIAD3638 CDS +2 3550727 3552031 no sun 16S rRNA m5C967 SAM-dependent methyltransferase 866 3NJ2I Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA J INFORMATION STORAGE AND PROCESSING Translation, ribosomal structure and biogenesis ACIAD3639 CDS -2 3552064 3552885 no zupT Zn transport protein (ZIP family) 488 3NMHC Mediates zinc uptake. May also transport other divalent cations P METABOLISM Inorganic ion transport and metabolism ACIAD3640 CDS -1 3552959 3553102 no conserved hypothetical protein 90.9 3NPUJ Putative methionine and alanine importer, small subunit S POORLY CHARACTERIZED Function unknown ACIAD3641 CDS -2 3553114 3554592 no conserved hypothetical protein; putative Na+-dependent transporters of the SNF family 956 3NKRA Belongs to the sodium neurotransmitter symporter (SNF) (TC 2.A.22) family S POORLY CHARACTERIZED Function unknown ACIAD3642 CDS -3 3555015 3556466 no putative aldehyde dehydrogenase 936 3NMG4 Belongs to the aldehyde dehydrogenase family C METABOLISM Energy production and conversion ACIAD3643 fCDS +3 3556614 3556742 pseudo fragment of conserved hypothetical protein (part 1) 45.1 3NIZ7 Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety M CELLULAR PROCESSES AND SIGNALING Cell wall/membrane/envelope biogenesis ACIAD3644 fCDS +2 3556709 3557311 pseudo fragment of conserved hypothetical protein (part 2) 219 3NIZ7 Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety M CELLULAR PROCESSES AND SIGNALING Cell wall/membrane/envelope biogenesis ACIAD3645 CDS +3 3557370 3558473 no conserved hypothetical protein 791 3NINM Putative zinc-binding metallo-peptidase S POORLY CHARACTERIZED Function unknown ACIAD3646 CDS +1 3558712 3559257 no putative protease 369 3NNZM DJ-1/PfpI family S POORLY CHARACTERIZED Function unknown ACIAD3647 CDS -2 3565216 3565782 no ppiA peptidyl-prolyl cis-trans isomerase precursor (PPIase) (Rotamase) 360 3NT4R PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides M CELLULAR PROCESSES AND SIGNALING Cell wall/membrane/envelope biogenesis ACIAD3648 CDS -2 3565909 3566979 no estA carboxylesterase (ALI-esterase) (B-esterase) (MONOBUTYRASE) (Cocaine esterase) (PROCAINE esterase) (METHYLBUTYRASE) 719 3NJTF Steryl acetyl hydrolase I METABOLISM Lipid transport and metabolism ACIAD3649 CDS -1 3567530 3567868 no conserved hypothetical protein 204 3NPIP S POORLY CHARACTERIZED Function unknown ACIAD3650 CDS -1 3568136 3569002 no conserved hypothetical protein; putative signal peptide 571 3NIG1 Metallo-beta-lactamase superfamily S POORLY CHARACTERIZED Function unknown ACIAD3651 CDS +2 3569075 3570001 no putative transcriptional regulator 576 3NJUX LysR substrate binding domain K INFORMATION STORAGE AND PROCESSING Transcription ACIAD3652 CDS +3 3570168 3570722 no grpE Hsp 24 nucleotide exchange factor 327 3NIUF Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ O CELLULAR PROCESSES AND SIGNALING Posttranslational modification, protein turnover, chaperones ACIAD3654 CDS +2 3570842 3572785 no dnaK chaperone Hsp70 in DNA biosynthesis/cell division 1211 3NIF5 Heat shock 70 kDa protein O CELLULAR PROCESSES AND SIGNALING Posttranslational modification, protein turnover, chaperones ACIAD3655 CDS +1 3573034 3573162 partial fragment of conserved hypothetical protein 77.4 3NKA3 Lactonase, 7-bladed beta-propeller G METABOLISM Carbohydrate transport and metabolism ACIAD3656 CDS +1 3573316 3573723 no putative phosphatase 256 3NNIW S POORLY CHARACTERIZED Function unknown ACIAD3657 CDS -1 3573779 3575074 no putative membrane-bound lytic murein transglycosylase 871 3NIM8 Lytic murein transglycosylase M CELLULAR PROCESSES AND SIGNALING Cell wall/membrane/envelope biogenesis ACIAD3658 CDS -1 3575624 3576775 no purK phosphoribosylaminoimidazole carboxylase ATPase subunit 758 3NJV0 Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR) F METABOLISM Nucleotide transport and metabolism ACIAD3659 CDS -1 3576845 3577360 no purE phosphoribosylaminoimidazole carboxylase, mutase subunit 326 3NIR5 Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR) F METABOLISM Nucleotide transport and metabolism ACIAD3662 CDS -2 3577711 3578058 no conserved hypothetical protein; putative membrane protein 240 3NP3U Putative member of DMT superfamily (DUF486) S POORLY CHARACTERIZED Function unknown ACIAD3663 CDS +3 3578322 3579683 no mpl UDP-N-acetylmuramate:L-alanyl-gamma-D-glutamyl-meso-diaminopimelate ligase 914 3NJUJ Reutilizes the intact tripeptide L-alanyl-gamma-D- glutamyl-meso-diaminopimelate by linking it to UDP-N- acetylmuramate M CELLULAR PROCESSES AND SIGNALING Cell wall/membrane/envelope biogenesis ACIAD3665 CDS +3 3579807 3580451 no conserved hypothetical protein; putative membrane protein 421 3NTB0 Acid phosphatase homologues I METABOLISM Lipid transport and metabolism ACIAD3666 CDS +1 3580732 3581712 no putative inner membrane protein alx 629 3NJEV Integral membrane protein TerC family P METABOLISM Inorganic ion transport and metabolism ACIAD3667 CDS -2 3581761 3582432 no conserved hypothetical protein 454 3NNAK Nucleotidyltransferase S POORLY CHARACTERIZED Function unknown ACIAD3668 CDS +2 3582461 3583783 no guaD guanine deaminase 895 3NJ8T Amidohydrolase family F METABOLISM Nucleotide transport and metabolism ACIAD3669 CDS +1 3583969 3584529 no hpt hypoxanthine phosphoribosyltransferase 364 3NK0V Belongs to the purine pyrimidine phosphoribosyltransferase family F METABOLISM Nucleotide transport and metabolism ACIAD3672 CDS +2 3584696 3584950 no conserved hypothetical protein; putative membrane protein 161 3NPB5 Transglycosylase associated protein S POORLY CHARACTERIZED Function unknown ACIAD3673 CDS -1 3584996 3585817 no putative thiol:disulfide interchange protein 547 3NK6X Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process O CELLULAR PROCESSES AND SIGNALING Posttranslational modification, protein turnover, chaperones ACIAD3674 CDS -2 3585871 3587034 no conserved hypothetical protein 783 3NMP7 S POORLY CHARACTERIZED Function unknown ACIAD3675 CDS -2 3587047 3588360 no putative outer membrane protein 813 3NIES Outer membrane efflux protein M CELLULAR PROCESSES AND SIGNALING Cell wall/membrane/envelope biogenesis ACIAD3675 CDS -2 3587047 3588360 no putative outer membrane protein 813 3NIES Outer membrane efflux protein U CELLULAR PROCESSES AND SIGNALING Intracellular trafficking, secretion, and vesicular transport ACIAD3676 CDS -2 3588370 3589977 no conserved hypothetical protein 1062 3NK0W GH3 auxin-responsive promoter I METABOLISM Lipid transport and metabolism ACIAD3676 CDS -2 3588370 3589977 no conserved hypothetical protein 1062 3NK0W GH3 auxin-responsive promoter Q METABOLISM Secondary metabolites biosynthesis, transport and catabolism ACIAD3677 CDS -3 3589974 3590840 no conserved hypothetical protein 596 3NSVQ S POORLY CHARACTERIZED Function unknown ACIAD3678 CDS -3 3590952 3592502 no putative multidrug resistence transporter (MFS superfamily) 1005 3NIHI Major Facilitator Superfamily E METABOLISM Amino acid transport and metabolism ACIAD3678 CDS -3 3590952 3592502 no putative multidrug resistence transporter (MFS superfamily) 1005 3NIHI Major Facilitator Superfamily G METABOLISM Carbohydrate transport and metabolism ACIAD3678 CDS -3 3590952 3592502 no putative multidrug resistence transporter (MFS superfamily) 1005 3NIHI Major Facilitator Superfamily P METABOLISM Inorganic ion transport and metabolism ACIAD3679 CDS -3 3592533 3593609 no putative multidrug resistance efflux pump 621 3NIZS HlyD membrane-fusion protein of T1SS V CELLULAR PROCESSES AND SIGNALING Defense mechanisms ACIAD3680 CDS -1 3594065 3595453 no trmE GTPase involved in tRNA modification and in thiophene and furan oxidation 884 3NJ32 Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34 J INFORMATION STORAGE AND PROCESSING Translation, ribosomal structure and biogenesis ACIAD3681 CDS -2 3595516 3597267 no oxaA Inner membrane protein (IMP) integration factor; binds TM regions of nascent IMPs; required for Sec-independent IMP integration; associated with the Sec translocase 1149 3NIHW Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins. Aids folding of multispanning membrane proteins U CELLULAR PROCESSES AND SIGNALING Intracellular trafficking, secretion, and vesicular transport ACIAD3682 CDS -3 3597273 3597593 no putative membrane protein insertion efficiency factor 231 3NNHN Could be involved in insertion of integral membrane proteins into the membrane S POORLY CHARACTERIZED Function unknown ACIAD3683 CDS -2 3597604 3597999 no rnpA RNase P, protein C5 component, processes tRNA, 4.5S RNA 252 3NN9R RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme J INFORMATION STORAGE AND PROCESSING Translation, ribosomal structure and biogenesis ACIAD3684 CDS -3 3598023 3598157 no rpmH 50S ribosomal protein L34 84.3 3NPR1 Belongs to the bacterial ribosomal protein bL34 family J INFORMATION STORAGE AND PROCESSING Translation, ribosomal structure and biogenesis