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KEGG Valine, leucine and isoleucine degradation pathway
Acinetobacter baylyi ADP1
Annotated/KOfamScan results [45]
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| MoveTo | Label | Region | Gene | EC number | Product | Evidence | KEGG map EC | KO | KO Definition | KO EC number |
|---|---|---|---|---|---|---|---|---|---|---|
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ACIAD0032 | - | 1.1.1.- | putative hydroxyacid dehydrogenase/reductase | validated | 1.1.1.31: 3-hydroxyisobutyrate dehydrogenase; | K00020 | K00020: 00020 | 1.1.1.31 | |
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ACIAD0334 | - | fadA | 2.3.1.16 | 3-ketoacyl-CoA thiolase (Fatty oxidation complex beta subunit) (Beta-ketothiolase) (Acetyl-CoA acyltransferase) | validated | 2.3.1.16: acetyl-CoA C-acyltransferase; 2.3.1.9: acetyl-CoA C-acetyltransferase; |
K00626, K00632 | K00626: 00626 K00632: 00632 |
2.3.1.16, 2.3.1.9 |
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ACIAD0335 | - | fadB | 4.2.1.17, 5.3.3.8, 1.1.1.35, 5.1.2.3 | fatty oxidation complex alpha subunit [Includes: Enoyl-CoA hydratase ; Delta(3)-cis-delta(2)-trans-enoyl-CoA isomerase ; 3-hydroxyacyl-CoA dehydrogenase; 3- hydroxybutyryl-CoA epimerase] | validated | 1.1.1.35: 3-hydroxyacyl-CoA dehydrogenase; 4.2.1.17: enoyl-CoA hydratase; |
K01825 | K01825: 01825 | 1.1.1.35, 4.2.1.17, 5.1.2.3, 5.3.3.8 |
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ACIAD0597 | - | ilvE | 2.6.1.42 | branched-chain amino acid transferase | validated | 2.6.1.42: branched-chain-amino-acid transaminase; | K00826 | K00826: 00826 | 2.6.1.42 |
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ACIAD0694 | - | fadA | 2.3.1.16, 2.3.1.9 | 3-ketoacyl-CoA thiolase, Acetyl-CoA acetyltransferase | validated | 2.3.1.16: acetyl-CoA C-acyltransferase; 2.3.1.9: acetyl-CoA C-acetyltransferase; |
K00626 | K00626: 00626 | 2.3.1.9 |
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ACIAD0998 | - | 1.2.1.3 | putative aldehyde dehydrogenase | validated | 1.2.1.3: aldehyde dehydrogenase (NAD+); | ||||
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ACIAD1020 | - | acoD | 1.8.1.4 | Dihydrolipoyl dehydrogenase (E3 component of acetoin cleaving system) (Dihydrolipoamide dehydrogenase) | validated | 1.8.1.4: dihydrolipoyl dehydrogenase; | K00382 | K00382: 00382 | 1.8.1.4 |
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ACIAD1412 | - | acadm | 1.3.8.1, 1.3.8.7 | medium-chain acyl-CoA dehydrogenase | validated | 1.3.8.1: short-chain acyl-CoA dehydrogenase; 1.3.8.7: medium-chain acyl-CoA dehydrogenase; |
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ACIAD1450 | - | catF | 2.3.1.- | beta-ketoadipyl CoA thiolase | validated | 2.3.1.16: acetyl-CoA C-acyltransferase; 2.3.1.9: acetyl-CoA C-acetyltransferase; |
K00626, K00632 | K00626: 00626 K00632: 00632 |
2.3.1.16, 2.3.1.9 |
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ACIAD1565 | - | 1.1.1.35 | putative 3-hydroxyacyl-CoA dehydrogenase (short-chain) (1.1.1.35/1.1.1.178) | validated | 1.1.1.178: 3-hydroxy-2-methylbutyryl-CoA dehydrogenase; 1.1.1.35: 3-hydroxyacyl-CoA dehydrogenase; |
K08683 | K08683: 08683 | 1.1.1.178, 1.1.1.35 | |
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ACIAD1569 | - | 2.3.1.- | putative 3-ketoacyl-CoA thiolase/acetyl-CoA acetyltransferase | validated | 2.3.1.9: acetyl-CoA C-acetyltransferase; | K00626 | K00626: 00626 | 2.3.1.9 | |
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ACIAD1604 | - | mmsA | 1.2.1.27 | methylmalonate-semialdehyde dehydrogenase, oxidoreductase protein | validated | 1.2.1.27: methylmalonate-semialdehyde dehydrogenase (CoA-acylating); | K00140 | K00140: 00140 | 1.2.1.18, 1.2.1.27 |
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ACIAD1605 | - | mmsB | 1.1.1.31 | 3-hydroxyisobutyrate dehydrogenase | validated | 1.1.1.31: 3-hydroxyisobutyrate dehydrogenase; | K00020 | K00020: 00020 | 1.1.1.31 |
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ACIAD1607 | - | acads | 1.3.8.1 | Acyl-CoA dehydrogenase, short-chain specific | validated | 1.3.8.1: short-chain acyl-CoA dehydrogenase; 1.3.8.7: medium-chain acyl-CoA dehydrogenase; |
K00248, K00249 | K00248: 00248 K00249: 00249 |
1.3.8.1, 1.3.8.7 |
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ACIAD1608 | - | FadB | 4.2.1.17 | Enoyl-CoA hydratase (valine degradation) (valine degradation) | validated | 4.2.1.17: enoyl-CoA hydratase; | K01692 | K01692: 01692 | 4.2.1.17 |
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ACIAD1609 | - | 4.2.1.17 | putative enoyl-CoA hydratase/isomerase family protein | validated | 4.2.1.17: enoyl-CoA hydratase; | ||||
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ACIAD1612 | - | 2.3.1.- | putative acetyl-CoA C-acetyltransferase with thiolase domain | validated | 2.3.1.9: acetyl-CoA C-acetyltransferase; | K00626 | K00626: 00626 | 2.3.1.9 | |
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ACIAD1613 | - | 1.3.8.- | putative acyl-CoA dehydrogenase protein (acdB-like) | validated | 1.3.8.7: medium-chain acyl-CoA dehydrogenase; | K00249 | K00249: 00249 | 1.3.8.7 | |
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ACIAD1689 | - | dcaF | 2.3.1.- | beta-ketoadipyl CoA thiolase | validated | 2.3.1.16: acetyl-CoA C-acyltransferase; 2.3.1.9: acetyl-CoA C-acetyltransferase; |
K00626, K00632 | K00626: 00626 K00632: 00632 |
2.3.1.16, 2.3.1.9 |
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ACIAD1692 | - | dcaE | 4.2.1.17 | Enoyl-CoA hydratase (branched-chain amino acid degradation) | validated | 4.2.1.17: enoyl-CoA hydratase; | |||
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ACIAD1693 | - | acads4 | 1.3.8.1 | Acyl-CoA dehydrogenase, short-chain specific | validated | 1.3.8.1: short-chain acyl-CoA dehydrogenase; 1.3.8.7: medium-chain acyl-CoA dehydrogenase; |
K00249 | K00249: 00249 | 1.3.8.7 |
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ACIAD1701 | - | 4.2.1.17 | putative enoyl-CoA hydratase | validated | 4.2.1.17: enoyl-CoA hydratase; | ||||
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ACIAD1706 | - | pcaF | 2.3.1.- | beta-ketoadipyl CoA thiolase | validated | 2.3.1.16: acetyl-CoA C-acyltransferase; 2.3.1.9: acetyl-CoA C-acetyltransferase; |
K00626, K00632 | K00626: 00626 K00632: 00632 |
2.3.1.16, 2.3.1.9 |
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ACIAD1723 | - | hcaD | 1.3.8.8 | acyl coenzyme A dehydrogenase | validated | 1.3.8.7: medium-chain acyl-CoA dehydrogenase; | K00249 | K00249: 00249 | 1.3.8.7 |
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ACIAD1726 | - | hcaA | 4.2.1.17 | enoyl-CoA hydratase/lyase | validated | 4.2.1.17: enoyl-CoA hydratase; | |||
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ACIAD1829 | - | 4.2.1.17 | putative enoyl-CoA hydratase (PaaG-like) | validated | 4.2.1.17: enoyl-CoA hydratase; | ||||
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ACIAD1886 | - | acads1 | 1.3.8.1 | Acyl-CoA dehydrogenase, short-chain specific | validated | 1.3.8.1: short-chain acyl-CoA dehydrogenase; 1.3.8.7: medium-chain acyl-CoA dehydrogenase; |
K00249 | K00249: 00249 | 1.3.8.7 |
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ACIAD1977 | - | 2.3.1.- | putative acyl-CoA thiolase | validated | 2.3.1.9: acetyl-CoA C-acetyltransferase; | K00626 | K00626: 00626 | 2.3.1.9 | |
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ACIAD2018 | - | acoD | 1.2.1.3 | Acetaldehyde dehydrogenase 2 (Acetaldehyde dehydrogenase II) (ACDH-II) | validated | 1.2.1.3: aldehyde dehydrogenase (NAD+); | |||
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ACIAD2226 | - | acads3 | 1.3.8.1 | Short-chain acyl CoA dehydrogenase | validated | 1.3.8.1: short-chain acyl-CoA dehydrogenase; 1.3.8.7: medium-chain acyl-CoA dehydrogenase; |
K00249 | K00249: 00249 | 1.3.8.7 |
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ACIAD2316 | - | 1.1.1.31 | putative 3-hydroxyisobutyrate dehydrogenase | validated | 1.1.1.31: 3-hydroxyisobutyrate dehydrogenase; | K00020 | K00020: 00020 | 1.1.1.31 | |
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ACIAD2351 | - | 4.2.1.17 | putative enoyl-CoA hydratase/isomerase | validated | 4.2.1.17: enoyl-CoA hydratase; | ||||
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ACIAD2416 | - | putative oxidoreductase, short-chain dehydrogenase/reductase family | validated | 1.1.1.178: 3-hydroxy-2-methylbutyryl-CoA dehydrogenase; 1.1.1.35: 3-hydroxyacyl-CoA dehydrogenase; |
K08683 | K08683: 08683 | 1.1.1.178, 1.1.1.35 | ||
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ACIAD2513 | - | atoD | 2.8.3.8 | acetoacetyl-CoA transferase, alpha subunit | validated | 2.8.3.5: 3-oxoacid CoA-transferase; | K01028 | K01028: 01028 | 2.8.3.5 |
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ACIAD2514 | - | atoA | 2.8.3.8 | acetoacetyl-CoA transferase, beta subunit | validated | 2.8.3.5: 3-oxoacid CoA-transferase; | K01029 | K01029: 01029 | 2.8.3.5 |
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ACIAD2516 | - | atoB | 2.3.1.9 | acetyl-CoA acetyltransferase with thiolase domain | validated | 2.3.1.9: acetyl-CoA C-acetyltransferase; | K00626 | K00626: 00626 | 2.3.1.9 |
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ACIAD2542 | - | tgnC | 1.2.1.3 | MFMB ((Z)-2-((N-methylformamido)methylene)-5-hydroxy-butyrolactone) dehydrogenase | validated | 1.2.1.3: aldehyde dehydrogenase (NAD+); | |||
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ACIAD2820 | - | 4.1.3.4 | putative hydroxymethylglutaryl-CoA lyase | validated | 4.1.3.4: hydroxymethylglutaryl-CoA lyase; | K01640 | K01640: 01640 | 4.1.3.4 | |
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ACIAD2874 | - | lpd | 1.8.1.4, 1.2.1.25 | dihydrolipoamide dehydrogenase E3 subunit of 2-oxoglutarate dehydrogenase complex (Glycine oxidation system L-factor) | validated | 1.8.1.4: dihydrolipoyl dehydrogenase; | K00382 | K00382: 00382 | 1.8.1.4 |
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ACIAD2988 | - | putative thiolase; putative acyl-CoA thiolase | validated | 2.3.1.9: acetyl-CoA C-acetyltransferase; | K00626 | K00626: 00626 | 2.3.1.9 | ||
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ACIAD2989 | - | 5.1.2.3 | putative 3-hydroxybutyryl-CoA epimerase | validated | 1.1.1.35: 3-hydroxyacyl-CoA dehydrogenase; 4.2.1.17: enoyl-CoA hydratase; |
K01782 | K01782: 01782 | 1.1.1.35, 4.2.1.17, 5.1.2.3 | |
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ACIAD3073 | - | 4.2.1.17 | putative enoyl-CoA hydratase/isomerase | validated | 4.2.1.17: enoyl-CoA hydratase; | ||||
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ACIAD3074 | - | glxR | 1.1.1.60 | 2-hydroxy-3-oxopropionate reductase | validated | 1.1.1.31: 3-hydroxyisobutyrate dehydrogenase; | K00020 | K00020: 00020 | 1.1.1.31 |
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ACIAD3145 | - | 1.8.1.4 | putative dihydrolipoamide dehydrogenase E3 component of pyruvate/2-oxoglutarate dehydrogenase complex | validated | 1.8.1.4: dihydrolipoyl dehydrogenase; | ||||
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ACIAD3191 | - | acads2 | 1.3.8.1 | Acyl-CoA dehydrogenase, short-chain specific | validated | 1.3.8.1: short-chain acyl-CoA dehydrogenase; 1.3.8.7: medium-chain acyl-CoA dehydrogenase; |
K00249 | K00249: 00249 | 1.3.8.7 |
Box in the studied region Box elsewhere in the genome
