CDSs classified by EGGNOG in COG category U
Acinetobacter baylyi ADP1 - chromosome ACIAD.1
U: CELLULAR PROCESSES AND SIGNALING -> Intracellular trafficking, secretion, and vesicular transport
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OG ID | OG function | Label | Gene | Product | COG | PFAM short name | KO |
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3NJUG | This protein specifically catalyzes the removal of signal peptides from prolipoproteins | ACIAD0021 | lspA | prolipoprotein signal peptidase (Signal peptidase II.) | COG0597 | Peptidase_A8 | K03101 |
3NNUZ | Fimbrial protein | ACIAD0119 | putative major fimbrial subunit protein precursor | COG3539 | K07345 | ||
3NN8Q | Pili assembly chaperone PapD, C-terminal domain | ACIAD0120 | putative pili assembly chaperone, required for type 1 fimbriae | COG3121 | PapD_C, PapD_N | K07346 | |
3NM2C | usher protein | ACIAD0121 | putative outer membrane usher protein (probable fimbrial usher protein) | COG3188 | PapC_C, PapC_N, Usher | K07347 | |
3NMY6 | Fimbrial protein | ACIAD0122 | putative fimbrial subunit, outer membrane protein | Fimbrial | |||
3NJFR | nucleotide-binding protein involved in DNA uptake | ACIAD0209 | putative Rossmann-fold nucleotide-binding protein involved in DNA uptake (Smf) | COG0758 | DNA_processg_A | K04096 | |
3NJC0 | Transmembrane secretion effector | ACIAD0228 | putative transport protein (MFS superfamily) | MFS_1 | |||
3NJQ1 | Outer membrane efflux protein | ACIAD0278 | tolC | channel-tunnel spanning the outer membrane and periplasm segregation of daughter chromosomes | COG1538 | OEP | K12340 |
3NJJQ | Type II secretion system protein C | ACIAD0293 | putative general secretion pathway protein | COG3031 | PDZ_2, T2SSC | K02452 | |
3NJK6 | Bacterial type II and III secretion system protein | ACIAD0294 | putative general secretion pathway protein | COG1450 | Secretin, Secretin_N | K02453 | |
3NN4U | Essential subunit of the Sec protein translocation channel SecYEG. Clamps together the 2 halves of SecY. May contact the channel plug during translocation | ACIAD0300 | secE | preprotein translocase IISP family, membrane subunit | COG0690 | SecE | K03073 |
3NKSJ | Belongs to the dicarboxylate amino acid cation symporter (DAACS) (TC 2.A.23) family | ACIAD0319 | aspT | D-aspartate transporter | SDF | ||
3NJ15 | Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue | ACIAD0360 | pilD | type 4 prepilin-like proteins leader peptide processing enzyme (Protein secretion protein XCPA)[Includes: Leader peptidase (Prepilin peptidase); N-methyltransferase ] | COG1989 | DiS_P_DiS, Peptidase_A24 | K02654 |
3NIKJ | Type II secretion system (T2SS), protein F | ACIAD0361 | pilC | type 4 fimbrial assembly protein | COG1459 | T2SSF | K02653 |
3NIQS | Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB | ACIAD0362 | pilB | type 4 fimbrial biogenesis protein | COG2804 | T2SSE, T2SSE_N | K02652 |
3NNTJ | Preprotein translocase SecG subunit | ACIAD0364 | secG | preprotein translocase IISP family, auxillary membrane component | COG1314 | SecG | K03075 |
3NPU7 | Fimbrial protein | ACIAD0387 | acuA | fimbrial protein AcuA | |||
3NM2C | usher protein | ACIAD0389 | acuC | fimbrial usher AcuC | COG3188 | PapC_N, Usher | K07347 |
3NIVU | general secretion pathway protein | ACIAD0411 | xcpS | general secretion pathway protein F | COG1459 | T2SSF | K02455 |
3NN5T | general secretion pathway protein | ACIAD0412 | xcpT | general secretion pathway protein G | COG2165 | N_methyl, T2SSG | K02456 |
3NJTM | Catalyzes the proton-dependent transport of glutamate and aspartate | ACIAD0481 | gltP | glutamate:aspartate symport protein (DAACS family) | COG1301 | SDF | K11102 |
3NJB7 | MotA TolQ ExbB proton channel | ACIAD0508 | putative biopolymer transport protein (ExbB) | COG0811 | MotA_ExbB | K03561 | |
3NN37 | Biopolymer transport protein | ACIAD0509 | putative biopolymer transport protein (ExbD) | COG0848 | ExbD | K03559 | |
3NIT5 | Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. Together with TatB, TatC is part of a receptor directly interacting with Tat signal peptides | ACIAD0521 | tatC | Sec-independent protein translocase protein | COG0805 | TatC | K03118 |
3NPHJ | Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. Together with TatC, TatB is part of a receptor directly interacting with Tat signal peptides. TatB may form an oligomeric binding site that transiently accommodates folded Tat precursor proteins before their translocation | ACIAD0522 | tatB | Sec-independent protein translocase protein | COG1826 | MttA_Hcf106 | K03117 |
3NPBJ | Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system | ACIAD0523 | tatA | Sec-independent protein translocase protein | COG1826 | MttA_Hcf106 | K03116 |
3NIST | Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins | ACIAD0534 | clpP | ATP-dependent Clp protease proteolytic subunit (Endopeptidase Clp) (Caseinolytic protease) (Protease Ti) (Heat shock protein F21.5) | COG0740 | CLP_protease | K01358 |
3NT5Q | Tetratricopeptide repeat | ACIAD0558 | pilF | type 4 fimbrial biogenesis protein | COG3063 | TPR_16 | K02656 |
3NKZC | Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA | ACIAD0587 | secF | preprotein translocase, IISP family, membrane subunit | COG0341 | SecD_SecF, Sec_GG | K03074 |
3NJM1 | Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA | ACIAD0588 | secD | preprotein translocase, IISP family, part of the channel | COG0342 | SecD-TM1, SecD_SecF, Sec_GG | K03072 |
3NNII | Preprotein translocase subunit YajC | ACIAD0589 | putative SecYEG protein translocase auxillary subunit (YajC) | COG1862 | YajC | K03210 | |
3NJG7 | Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving both as a receptor for the preprotein-SecB complex and as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane | ACIAD0648 | secA | preprotein translocase, secretion protein of IISP family | COG0653 | SEC-C, SecA_DEAD, SecA_PP_bind, SecA_SW | K03070 |
3NNW2 | Small Multidrug Resistance protein | ACIAD0691 | sugE | suppressor of gro | COG2076 | Multi_Drug_Res | K11741 |
3NMDE | Type II transport protein GspH | ACIAD0695 | putative type 4 fimbrial biogenesis protein FimT | COG2165 | GspH, N_methyl | K08084 | |
3NIEX | Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY. Interaction with FtsY leads to the transfer of the RNC complex to the Sec translocase for insertion into the membrane, the hydrolysis of GTP by both Ffh and FtsY, and the dissociation of the SRP-FtsY complex into the individual components | ACIAD0839 | ffh | 4.5S-RNP protein, GTP binding export factor, part of signal recognition particle with 4.5 RNA | COG0541 | SRP54, SRP54_N, SRP_SPB | K03106 |
3NKGE | Type II/IV secretion system protein | ACIAD0911 | pilU | twitching motility protein | COG2805 | T2SSE | K02670 |
3NJ7T | twitching motility protein | ACIAD0912 | pilT | twitching motility protein | COG2805 | T2SSE | K02669 |
3NMBZ | POTRA domain | ACIAD0939 | putative outer membrane transporter CdiB | POTRA_2, POTRA_3, ShlB | |||
3NK7X | Large exoproteins involved in heme utilization or adhesion | ACIAD0940 | cdiA | toxin CdiA | COG3210 | ESPR, Fil_haemagg, Fil_haemagg_2 | K15125 |
COG3210 | domain, Protein | ACIAD0946 | hypothetical protein | PT-VENN | |||
COG3210 | domain, Protein | ACIAD0946 | hypothetical protein | PT-VENN | |||
3NK7X | Large exoproteins involved in heme utilization or adhesion | ACIAD0948 | putative hemagglutinin/hemolysin-related protein | Fil_haemagg_2 | |||
3NK6G | BCCT, betaine/carnitine/choline family transporter | ACIAD1011 | BeT1 | high-affinity choline transporter (BCCT family) | COG1292 | BCCT | K02168 |
3NJ21 | MarC family integral membrane protein | ACIAD1013 | putative membrane protein | MarC | |||
3NT4S | Belongs to the dicarboxylate amino acid cation symporter (DAACS) (TC 2.A.23) family | ACIAD1026 | dctA | aerobic C4-dicarboxylate transport protein | COG1301 | SDF | K11103 |
3NJKG | Outer membrane efflux protein | ACIAD1160 | putative membrane channel protein | OEP | |||
3NKUH | Belongs to the dicarboxylate amino acid cation symporter (DAACS) (TC 2.A.23) family | ACIAD1191 | putative transport protein | COG1823 | SDF | K06956 | |
3NJ7X | Peptidase family S49 N-terminal | ACIAD1216 | putative protease (SohB) | COG0616 | Peptidase_S49, Peptidase_S49_N | K04774 | |
3NM0Q | hemolysin activation secretion protein | ACIAD1290 | hypothetical protein; putative signal peptide | ||||
3NIFQ | Involved in a type II secretion system (T2SS, formerly general secretion pathway, GSP) for the export of proteins | ACIAD1319 | putative general secretion pathway protein L (GspL family) | COG3297 | GspL_C, T2SSL | K02461 | |
3NKSJ | Belongs to the dicarboxylate amino acid cation symporter (DAACS) (TC 2.A.23) family | ACIAD1339 | aspY | L- and D-aspartate transporter | SDF | ||
3NJQY | Outer membrane efflux protein | ACIAD1487 | putative outer membrane efflux protein, type I secretion protein | COG1538 | OEP | K12543 | |
3NMEZ | Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. Together with TatB, TatC is part of a receptor directly interacting with Tat signal peptides | ACIAD1520 | tatC | Sec-independent protein secretion pathway, component C. | COG0805 | TatC | K03118 |
3NNDP | Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes | ACIAD1521 | tatB | Sec-independent protein secretion pathway, component B | COG1826 | K03117 | |
3NPIY | Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system | ACIAD1522 | tatA | Sec-independent protein secretion pathway, translocase protein | COG1826 | MttA_Hcf106 | K03116 |
3NTIN | MotA/TolQ/ExbB proton channel family | ACIAD1529 | putative biopolymer transport protein (ExbB-like) | COG0811 | MotA_ExbB | K03561 | |
3NN64 | Biopolymer transport protein ExbD/TolR | ACIAD1530 | putative biopolymer transport protein (ExbD-like) | COG0848 | ExbD | K03559 | |
3NN1A | MotA/TolQ/ExbB proton channel family | ACIAD1589 | putative biopolymer transport protein (ExbB-like) | COG0811 | MotA_ExbB | K03561 | |
3NN7B | Biopolymer transport protein ExbD/TolR | ACIAD1590 | putative biopolymer transport protein (ExbD-like) | COG0848 | ExbD | K03559 | |
3NIF1 | Coiled stalk of trimeric autotransporter adhesin | ACIAD1639 | putative surface protein (partial adhesin) | YadA_anchor, YadA_stalk | K21449 | ||
3NKF0 | Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane | ACIAD1697 | dcaP | porin precurseur in catabolism of dicarboxylic acids | Sugarporin_N | ||
3NK1Q | Component of the transport system for branched-chain amino acids | ACIAD1988 | braZ | branched chain amino acid transporter | COG1114 | Branch_AA_trans | K03311 |
3NJNC | Responsible for the transport of dicarboxylates such as succinate, fumarate, and malate across the membrane | ACIAD2227 | dctA | aerobic C4-dicarboxylate transport protein | COG1301 | SDF | K11103 |
3NJR5 | Type II secretion system (T2SS), protein E, N-terminal domain | ACIAD2241 | putative secretion pathway ATPase | COG2804 | T2SSE, T2SSE_N | K02454 | |
3NJ2A | Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC). Interaction with SRP-RNC leads to the transfer of the RNC complex to the Sec translocase for insertion into the membrane, the hydrolysis of GTP by both Ffh and FtsY, and the dissociation of the SRP-FtsY complex into the individual components | ACIAD2296 | ftsY | cell division protein | COG0552 | SRP54, SRP54_N | K03110 |
3NJ8R | Type II secretion system (T2SS), protein K | ACIAD2354 | xcpX | general secretion pathway protein K | COG3156 | T2SSK | K02460 |
3NKPG | general secretion pathway protein | ACIAD2355 | xcpW | general secretion pathway protein J precursor (PilD-dependent protein pddD) | COG2165 | N_methyl, T2SSJ | K02459 |
3NNHX | Type II secretion system (T2SS), protein I | ACIAD2356 | xcpV | general secretion pathway protein I precursor (PilD-dependent protein pddC) | COG2165 | N_methyl, T2SSI | K02458 |
3NNKH | PilZ domain | ACIAD2360 | pilZ | type 4 fimbrial biogenesis protein | COG3215 | PilZ | K02676 |
3NKSE | Na+ dependent nucleoside transporter C-terminus | ACIAD2389 | putative transport protein; putative NUP family transport protein | COG1972 | Nucleos_tra2_C, Nucleos_tra2_N | K16324 | |
1RPQJ | MFS-type transporter | ACIAD2472 | putative transport protein (MFS superfamily) | MFS_1 | |||
3NM0Q | hemolysin activation secretion protein | ACIAD2540 | conserved hypothetical protein; putative signal peptide | ||||
3NSPC | Permease for cytosine/purines, uracil, thiamine, allantoin | ACIAD2541 | tgnP | trigonelline permease | COG1953, COG1457 | Transp_cyt_pur | K03457 |
3NTK1 | Domain of unknown function (DUF4845) | ACIAD2582 | conserved hypothetical protein; putative signal peptide | DUF4845 | |||
3NIUQ | Belongs to the peptidase S26 family | ACIAD2583 | lepB | leader peptidase (signal peptidase I) , serine protease | COG0681 | Peptidase_S24, Peptidase_S26 | K03100 |
3NK2Q | MotA/TolQ/ExbB proton channel family | ACIAD2619 | tolQ | tolerance to group A colicins, single-stranded DNA filamentous phage, required for OM integrity | COG0811 | MotA_ExbB | K03562 |
3NK24 | Biopolymer transport protein ExbD/TolR | ACIAD2620 | tolR | tolerance to group A colicins, single-stranded DNA filamentous phage, required for OM integrity | COG0848 | ExbD | K03560 |
3NJZ9 | Involved in the TonB-independent uptake of proteins | ACIAD2622 | tolB | tolerance to colicins E2, E, A, and K, required for OM integrity | COG0823 | PD40, TolB_N | K03641 |
3NJ3R | signal peptide peptidase SppA | ACIAD2637 | putative protease; putative signal peptide peptidase sppA | COG0616 | Peptidase_S49 | K04773 | |
3NIK7 | Outer membrane efflux protein | ACIAD2648 | conserved hypothetical protein; putative outer membrane efflux protein | OEP | |||
1RNRK | Large exoproteins involved in heme utilization or adhesion | ACIAD2707 | hypothetical protein | COG3210 | DUF637, Fil_haemagg_2, Haemagg_act | K15125 | |
3NK7X | Large exoproteins involved in heme utilization or adhesion | ACIAD2784 | cdiA | toxin CdiA | COG3210 | DUF637, ESPR, Haemagg_act, PT-VENN, Tox-REase-7 | K15125 |
3NMBZ | POTRA domain | ACIAD2785 | putative outer membrane transporter CdiB | POTRA_2, POTRA_3, ShlB | |||
3NK4E | Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane | ACIAD2824 | conserved hypothetical protein; putative protein (DcaP-like) | ||||
3NIHE | AcrB/AcrD/AcrF family | ACIAD2836 | putative multidrug efflux protein | ACR_tran | |||
3NTMV | TIGRFAM Outer membrane protein | ACIAD2866 | bap | biofilm associated protein | |||
3NM0Q | hemolysin activation secretion protein | ACIAD2890 | conserved hypothetical protein; putative signal peptide | ||||
3NJFB | COG0457 FOG TPR repeat | ACIAD2901 | conserved hypothetical protein; putative signal peptide | TPR_19 | |||
3NJ6H | COG1585 Membrane protein implicated in regulation of membrane protease activity | ACIAD2966 | conserved hypothetical protein; putative membrane protein | NfeD | |||
3NIQS | Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB | ACIAD3024 | xcpR | general secretion pathway protein E (Type II traffic warden ATPase) | COG2804 | T2SSE | K02454 |
3NK4T | One of the proteins required for the normal export of preproteins out of the cell cytoplasm. It is a molecular chaperone that binds to a subset of precursor proteins, maintaining them in a translocation-competent state. It also specifically binds to its receptor SecA | ACIAD3122 | secB | molecular chaperone in protein export | COG1952 | SecB | K03071 |
3NMIK | PFAM Ig domain protein, group 1 domain protein | ACIAD3144 | conserved hypothetical protein | Big_1 | |||
3NKTT | Hep Hag repeat protein | ACIAD3177 | conserved hypothetical protein; putative conserved domain | ||||
3NIK2 | The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently | ACIAD3199 | secY | secretion protein | COG0201 | SecY | K03076 |
3NJTM | Catalyzes the proton-dependent transport of glutamate and aspartate | ACIAD3230 | putative Proton/sodium-glutamate symport protein | SDF | |||
3NNR0 | Type IV minor pilin ComP, DNA uptake sequence receptor | ACIAD3314 | comF | type IV pilus assembly protein ComF | COG2165 | ComP_DUS, N_methyl | K02655 |
3NP0M | Prokaryotic N-terminal methylation motif | ACIAD3315 | comE | type IV pilus assembly protein ComE | COG2165 | ComP_DUS, N_methyl | K02655 |
3NKHS | Tfp pilus assembly protein tip-associated adhesin PilY1 | ACIAD3316 | comC | competence factor involved in DNA binding and uptake | COG3419 | Neisseria_PilC | K02674 |
3NMPE | Type IV Pilus-assembly protein W | ACIAD3318 | comB | pilin like competence factor | N_methyl, PilW | K02672 | |
3NTIK | type IV pilus modification protein PilV | ACIAD3319 | putative type 4 fimbrial biogenesis protein (PilV) | COG2165 | N_methyl | K02671 | |
3NNBB | Prokaryotic N-terminal methylation motif | ACIAD3321 | FimU | type IV pilus assembly protein FimU | COG2165 | GspH, N_methyl | K08085 |
3NKPQ | Outer membrane usher protein | ACIAD3334 | putative usher protein involved in fimbrial biogenesis (PapC/CsuD) | COG3188 | Usher | K07347 | |
3NPSI | pilus assembly protein major pilin PilA | ACIAD3338 | comP | competence factor involved in DNA binding and uptake | COG2165 | N_methyl, Pilin | K02650 |
3NIVQ | Secretin and TonB N terminus short domain | ACIAD3355 | ComQ | outer membrane protein ComQ/PilQ | COG1450 | AMIN, STN, Secretin, Secretin_N | K02666 |
3NJEN | Pilus assembly protein, PilP | ACIAD3356 | pilP | type IV pilus assembly protein PilP | COG3168 | PilP | K02665 |
3NJ8W | Pilus assembly protein, PilO | ACIAD3357 | putative membrane protein (ComO) | COG3167 | PilO | K02664 | |
3NIH9 | Fimbrial assembly protein (PilN) | ACIAD3359 | putative membrane protein (ComN) | COG3166 | PilN | K02663 | |
3NKVX | Type IV pilus assembly protein PilM; | ACIAD3360 | putative membrane protein (ComM) | COG0849 | PilM_2 | K02662 | |
3NJYG | Outer membrane efflux protein | ACIAD3378 | czcC | outer membrane protein precursor | COG1538 | OEP | K15725 |
3NJKG | Outer membrane efflux protein | ACIAD3421 | putative outer membrane protein precursor | OEP | |||
3NM0Q | hemolysin activation secretion protein | ACIAD3483 | hypothetical protein; putative conserved domain | ||||
3NIES | Outer membrane efflux protein | ACIAD3675 | putative outer membrane protein | OEP | |||
3NIHW | Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins. Aids folding of multispanning membrane proteins | ACIAD3681 | oxaA | Inner membrane protein (IMP) integration factor; binds TM regions of nascent IMPs; required for Sec-independent IMP integration; associated with the Sec translocase | COG0706 | 60KD_IMP, YidC_periplas | K03217 |