Genomic Tools

OG ID	OG function	Label	Gene	Product	COG	PFAM short name	KO
3NIZC	Belongs to the acetyltransferase family. ArgA subfamily	ACIAD0039	argA	N-alpha-acetylglutamate synthase (amino-acid acetyltransferase)	COG0548, COG1246	AA_kinase, Acetyltransf_1	K14682
3NKI3	Belongs to the DegT DnrJ EryC1 family	ACIAD0095	per	perosamine synthetase (WeeJ)		DegT_DnrJ_EryC1
3NJRT	Aminotransferase class I and II	ACIAD0112	tyrB	tyrosine aminotransferase, tyrosine repressible, PLP-dependent	COG1448	Aminotran_1_2	K00832
3NJK5	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids	ACIAD0116	dadX	alanine racemase 2, PLP-binding, catabolic	COG0787	Ala_racemase_C, Ala_racemase_N	K01775
3NJUE	Amino acid permease	ACIAD0118	cycA	APC family, D-serine/D-alanine/glycine transport protein	COG1113	AA_permease	K11737
3NJPE	EamA-like transporter family	ACIAD0125		conserved hypothetical protein; putative membrane protein		EamA
3NIFI	Belongs to the DapA family	ACIAD0130	kdgD	5-dehydro-4-deoxyglucarate dehydratase (5-keto-4-deoxy- glucarate dehydratase)	COG0329	DHDPS	K01707
3NJWA	lysine exporter protein (LysE YggA)	ACIAD0147		putative amino acid transporter		LysE
3NJKK	EamA-like transporter family	ACIAD0161		putative transporter		EamA
3NIVK	LysE type translocator	ACIAD0173	rhtB	homoserine/homoserine lactone efflux protein	COG1280	LysE	K05834
3NSWZ	Major Facilitator Superfamily	ACIAD0195		putative transporter (MFS superfamily)		MFS_1
3NIXW	EamA-like transporter family	ACIAD0197		putative membrane protein		EamA
3NKDF	Sugar (and other) transporter	ACIAD0223	shiA	shikimate and dehydroshikimate transport protein (MFS superfamily)	COG0477	MFS_1	K08172
3NKDC	Sugar (and other) transporter	ACIAD0233	niaP	niacin transporer	COG0477	MFS_1	K08369
3NJ24	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides	ACIAD0253	pepA	aminopeptidase A	COG0260	Peptidase_M17, Peptidase_M17_N	K01255
3NIF7	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine	ACIAD0263	thrC	threonine synthase, pyridoxal-5'-phosphate-dependent enzyme	COG0498	PALP	K01733
3NKC8	homoserine dehydrogenase	ACIAD0264	hom	homoserine dehydrogenase	COG0460	ACT, Homoserine_dh, NAD_binding_3	K00003
3NJHZ	argininosuccinate lyase	ACIAD0283	argH	argininosuccinate lyase (Arginosuccinase) (ASAL)	COG0165	ASL_C2, Lyase_1	K01755
3NIJW	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia	ACIAD0297	trpE	anthranilate synthase component I	COG0147	Anth_synt_I_N, Chorismate_bind	K01657
3NJPS	EamA-like transporter family	ACIAD0358		putative tranporter		EamA
3NK5C	belongs to the PRA-CH family	ACIAD0380	hisIE	bifunctional protein [Includes: phosphoribosyl-AMP cyclohydrolase; phosphoribosyl-ATP pyrophosphatase]	COG0139, COG0140	PRA-CH, PRA-PH	K11755
3NSX0	Sugar (and other) transporter	ACIAD0395	citA	citrate-proton symporter (Citrate transporter) (Citrate carrier protein) (Citrate utilization determinant) (Citrate utilization protein A)		MFS_1
3NJ6E	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)	ACIAD0418	aroE	dehydroshikimate reductase, NAD(P)-binding	COG0169	Shikimate_DH, Shikimate_dh_N	K00014
3NITK	haloacid dehalogenase-like hydrolase	ACIAD0456	hisK	histidinol-phosphatase		HAD
3NJM4	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate	ACIAD0463	leuC	3-isopropylmalate dehydratase (isomerase), subunit with LeuD	COG0065	Aconitase	K01703
3NK10	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate	ACIAD0466	leuD	3-isopropylmalate isomerase (dehydratase), subunit with LeuC	COG0066	Aconitase_C	K01704
3NK2W	Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate	ACIAD0469	leuB	3-isopropylmalate dehydrogenase	COG0473	Iso_dh	K00052
3NJPT	Asparaginase	ACIAD0476		putative L-asparaginase I (AnsA)	COG0252	Asparaginase	K01424
3NJ2Q	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate	ACIAD0479	asd	aspartate-semialdehyde dehydrogenase, NAD(P)-binding	COG0136	Semialdhyde_dh, Semialdhyde_dhC	K00133
3NT7H	LysE type translocator	ACIAD0486		putative transporter protein		LysE
3NK6R	Transfers a succinyl group from succinyl-CoA to L- homoserine, forming succinyl-L-homoserine	ACIAD0529	metXS	Homoserine O-succinyltransferase	COG2021	Abhydrolase_1	K00641
3NJF8	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)	ACIAD0530	leuA	2-isopropylmalate synthase (Alpha-isopropylmalate synthase) (Alpha-IPM synthetase)	COG0119	HMGL-like, LeuA_dimer	K01649
3NKHE	Belongs to the IlvD Edd family	ACIAD0542	edd	phosphogluconate dehydratase (6-phosphogluconate dehydratase)	COG0129	ILVD_EDD	K01690
3NJAN	GntP family permease	ACIAD0544	gntT	high-affinity gluconate permease (GntP family)	COG2610	GntP_permease	K03299
3NJAC	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate	ACIAD0547	proA	gamma-glutamyl phosphate reductase (GPR) (Glutamate-5- semialdehyde dehydrogenase) (Glutamyl-gamma-semialdehyde dehydrogenase) (GSA dehydrogenase)	COG0014	Aldedh	K00147
3NJM0	histidine ammonia-lyase activity	ACIAD0574	hutH	histidine ammonia-lyase protein (Histidase)	COG2986	Lyase_aromatic	K01745
3NK5G	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family	ACIAD0597	ilvE	branched-chain amino acid transferase	COG0115	Aminotran_4	K00826
3NIWQ	Belongs to the TrpF family	ACIAD0635	trpF	N-(5'-phosphoribosyl)anthranilate isomerase (PRAI)	COG0135	PRAI	K01817
3NJAP	The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine	ACIAD0636	trpB	tryptophan synthase beta chain	COG0133	PALP	K01696
3NKMT	The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3- phosphate	ACIAD0642	trpA	tryptophan synthase alpha chain	COG0159	Trp_syntA	K01695
3NJGF	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate	ACIAD0650	argJ	bifunctional protein [Includes: glutamate N-acetyltransferase (Ornithine acetyltransferase) (Ornithine transacetylase) (OATASE); amino-acid acetyltransferase (N-acetylglutamate synthase) (AGS)]	COG1364	ArgJ	K00620
3NIG8	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity	ACIAD0661	hisG	ATP-phosphoribosyltransferase	COG0040	HisG	K00765
3NJH3	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine	ACIAD0663	hisD	Histidinol dehydrogenase (HDH)	COG0141	Histidinol_dh	K00013
3NIR7	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily	ACIAD0664	hisC	histidinol-phosphate aminotransferase	COG0079	Aminotran_1_2	K00817
3NIKM	chorismate binding enzyme	ACIAD0665	pabB	p-aminobenzoate synthetase	COG0147	Chorismate_bind	K01665
3NKFB	Amino acid permease	ACIAD0700	lysP	lysine-specific permease	COG0833	AA_permease	K11733
3NK9X	Pyridoxal-phosphate dependent enzyme	ACIAD0753		putative D-cysteine desulfhydrase (DcyD)	COG2515	PALP	K05396
3NTGK	haloacid dehalogenase-like hydrolase	ACIAD0754		Putative phosphoserine phosphatase		HAD
3NKWK	Major facilitator superfamily	ACIAD0756		putative transporter (MFS superfamily)		MFS_1
3NTES	LysE type translocator	ACIAD0759		putative threonine efflux protein (RhtC)		LysE
3NJKU	LysE type translocator	ACIAD0775		conserved hypothetical protein; putative membrane protein		LysE
3NIXJ	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls	ACIAD0791	dapE	succinyl-diaminopimelate desuccinylase	COG0624	M20_dimer, Peptidase_M20	K01439
3NJ83	Sugar (and other) transporter	ACIAD0802		putative bicyclomycin/multidrug transport protein (MFS superfamily)	COG0477	MFS_1	K07552
3NIJ7	Sodium:alanine symporter family	ACIAD0805		putative amino-acid transport protein	COG1115	Na_Ala_symp	K03310
3NII6	Reduction of activated sulfate into sulfite	ACIAD0833		putative 5'-adenylylsulfate reductase (APS reductase) (cysH-like)	COG0175	PAPS_reduct	K00390
3NJXD	haloacid dehalogenase-like hydrolase	ACIAD0834		putative homoserine kinase (ThrH)	COG0560	Hydrolase	K02203
3NJNE	8-amino-7-oxononanoate synthase	ACIAD0857	bioF	8-amino-7-oxononanoate synthase	COG0156	Aminotran_1_2	K00652
3NQY0	Pfam:DUF955	ACIAD0874		conserved hypothetical protein ; putative phage related protein		Mrr_cat, Peptidase_M78
3NJA7	Belongs to the acetylglutamate kinase family. ArgB subfamily	ACIAD0903	argB	acetylglutamate kinase	COG0548	AA_kinase	K00930
3NM3M	Transglutaminase/protease-like homologues	ACIAD0915		conserved hypothetical protein; putative transglutaminase-like enzyme		Transglut_core
3NK8N	FAD dependent oxidoreductase	ACIAD0922		putative D-amino acid oxidase	COG0665	DAO	K03153
3NJ0E	Sugar (and other) transporter	ACIAD0927	emrB	multidrug resistance transmembrane protein (MFS superfamily)	COG0477	MFS_1	K03446
3NK4G	Phosphoribosyl synthetase-associated domain	ACIAD0964	prs	ribose-phosphate pyrophosphokinase (Phosphoribosyl pyrophosphate synthetase)	COG0462	Pribosyltran	K00948
3NMPW	Uncharacterised MFS-type transporter YbfB	ACIAD0982	vanK	vanillate transporter (MFS superfamily)		MFS_1
3NKI2	Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily	ACIAD0990		putative dioxygenase		Glyoxalase
3NIP9	Thiamine pyrophosphate enzyme, central domain	ACIAD0999		putative acetolactate synthase (IlvB-like)	COG0028	TPP_enzyme_C, TPP_enzyme_M, TPP_enzyme_N	K01652
3NMA8	Transmembrane secretion effector	ACIAD1006		putative permease (MFS superfamily)		MFS_3
3NK8U	Involved in the biosynthesis of the osmoprotectant glycine betaine. Catalyzes the oxidation of choline to betaine aldehyde and betaine aldehyde to glycine betaine at the same rate	ACIAD1008	betA	choline dehydrogenase, a flavoprotein	COG2303	GMC_oxred_C, GMC_oxred_N	K00108
3NKBG	Major facilitator superfamily	ACIAD1036		putative permease (MFS superfamily)		MFS_1
3NMCU	Belongs to the glutaminase family	ACIAD1040		putative glutaminase	COG2066	Glutaminase	K01425
3NJ8A	B12 binding domain	ACIAD1045	metH	methionine synthase (B12-dependent homocysteine-N5-methyltetrahydrofolate transmethylase, repressor of metE and metF)	COG1410, COG0646	B12-binding, B12-binding_2, Met_synt_B12, Pterin_bind, S-methyl_trans	K00548
3NKT6	Belongs to the serine threonine dehydratase family. DsdA subfamily	ACIAD1048	dsdA	D-serine deaminase (dehydratase)	COG3048	PALP	K01753
3NJ8U	GDSL-like Lipase/Acylhydrolase family	ACIAD1057	tesA	multifunctional protein [Includes: acyl-CoA thioesterase I; protease I; lysophospholipaseL(I)]	COG2755	Lipase_GDSL_2	K10804
3NKEF	Serine aminopeptidase, S33	ACIAD1064		putative hydrolase (EstB)		Abhydrolase_1
3NNWE	Belongs to the urease gamma subunit family	ACIAD1089	ureA	urease gamma subunit	COG0831	Urease_gamma	K01430
3NP3Z	Belongs to the urease beta subunit family	ACIAD1090	ureB	urease beta subunit	COG0832	Urease_beta	K01429
3NINC	Belongs to the metallo-dependent hydrolases superfamily. Urease alpha subunit family	ACIAD1091	ureC	urease alpha subunit	COG0804	Amidohydro_1, Urease_alpha	K01428
3NITF	Belongs to the Glu Leu Phe Val dehydrogenases family	ACIAD1110	gdhA	glutamate dehydrogenase, NADP-specific	COG0334	ELFV_dehydrog, ELFV_dehydrog_N	K00262
3NJMZ	Belongs to the peptidase M24B family	ACIAD1126	pepP	aminopeptidase P	COG0006	AMP_N, Peptidase_M24	K01262
3NJZZ	Bacterial extracellular solute-binding proteins, family 5 Middle	ACIAD1139		putative oligopeptide transport protein (ABC superfamily, peri_bind)	COG4166	SBP_bac_5	K13893
3NTAU	Belongs to the peptidase S1B family	ACIAD1144		conserved hypothetical protein
3NTK8	Belongs to the peptidase S1B family	ACIAD1145		conserved hypothetical protein
3NJ12	amino acid	ACIAD1147		putative APC family, S-methylmethionine transporter (MmuP)	COG0833	AA_permease	K16235
3NKG1	Belongs to the argininosuccinate synthase family. Type	ACIAD1151	argG	argininosuccinate synthetase	COG0137	Arginosuc_synth	K01940
3NKKR	EamA-like transporter family	ACIAD1154		putative transport protein		EamA
3NM0M	Catalyzes the conversion of urocanate to 4-imidazolone- 5-propionate	ACIAD1166		fragment of urocanate hydratase (Urocanase) (Imidazolonepropionate hydrolase) (HutU)		Urocanase, Urocanase_C, Urocanase_N
3NJM0	histidine ammonia-lyase activity	ACIAD1167		fragment of Histidine ammonia-lyase (Histidase) (HutH)	COG2986	Lyase_aromatic	K01745
3NK7N	Amino acid permease	ACIAD1168		putative histidine transport protein (APC family)	COG1113	AA_permease	K16234
3NJKQ	Catalyzes the conversion of N-formimidoyl-L-glutamate to L-glutamate and formamide	ACIAD1169		fragment of formimidoylglutamase (Formiminoglutamase) (Formiminoglutamate hydrolase) (HutG)		Arginase
3NJ5V	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family	ACIAD1210	dat	diaminobutyrate--2-oxoglutarate aminotransferase (L- diaminobutyric acid transaminase) (Diaminobutyrate transaminase) (DABA aminotransferase) (DABA-AT) (L-2,4-diaminobutyrate:2-ketoglutarate 4- aminotransferase)	COG0160, COG4992	Aminotran_3	K00836
3NIHU	Pyridoxal-dependent decarboxylase conserved domain	ACIAD1211	ddc	L-2,4-diaminobutyrate decarboxylase	COG0076	Pyridoxal_deC	K13745
3NKVR	acetylornithine aminotransferase	ACIAD1231	argD	acetylornithine aminotransferase	COG0160, COG4992	Aminotran_3	K00821
3NKCG	Belongs to the aspartokinase family	ACIAD1252	lysC	aspartate kinase	COG0527	AA_kinase, ACT, ACT_7	K00928
3NM0B	Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine	ACIAD1257	hisZ	ATP phosphoribosyltransferase	COG3705	tRNA-synt_His	K02502
3NJMA	Belongs to the IlvD Edd family	ACIAD1266	ilvD	dihydroxy-acid dehydratase	COG0129	ILVD_EDD	K01687
3NTMJ	Amino acid permease	ACIAD1276		putative amino acid transporter		AA_permease_2
3NKVR	acetylornithine aminotransferase	ACIAD1284	aruC	Succinylornithine transaminase	COG0160, COG4992	Aminotran_3	K00840
3NJDN	Arginine N-succinyltransferase beta subunit	ACIAD1286	aruG	arginine/ornithine succinyltransferase AII subunit	COG3138	AstA	K00673
3NKQD	Catalyzes the hydrolysis of N(2)-succinylarginine into N(2)-succinylornithine, ammonia and CO(2)	ACIAD1288	aruB	succinylarginine dihydrolase	COG3724	AstB	K01484
3NK6H	Belongs to the AspA AstE family. Succinylglutamate desuccinylase subfamily	ACIAD1289	aruE	succinylglutamate desuccinylase	COG2988	AstE_AspA	K05526
3NM72	Belongs to the bacterial solute-binding protein 3 family	ACIAD1297		putative amino acid transporter (ABC superfamily, peri_bind)	COG0834	SBP_bac_3	K02030
3NKJ1	Arginase family	ACIAD1299	gbuA	guanidinobutyrase	COG0010	Arginase	K12255
3NJHM	Amino acid permease	ACIAD1343	aroP	aromatic amino acid transporter (APC family)	COG1113	AA_permease	K11734
3NJ5D	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA	ACIAD1357	ilvA	Threonine dehydratase biosynthetic (Threonine deaminase)	COG1171	PALP, Thr_dehydrat_C	K01754
3NJA9	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde	ACIAD1360	argC	N-acetyl-gamma-glutamyl-phosphate reductase	COG0002	Semialdhyde_dh, Semialdhyde_dhC	K00145
3NIKC	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline	ACIAD1366	argF	ornithine carbamoyltransferase	COG0078	OTCace, OTCace_N	K00611
3NKJK	Master enzyme that delivers sulfur to a number of partners involved in Fe-S cluster assembly, tRNA modification or cofactor biosynthesis. Catalyzes the removal of elemental sulfur atoms from cysteine to produce alanine. Functions as a sulfur delivery protein for Fe-S cluster synthesis onto IscU, an Fe-S scaffold assembly protein, as well as other S acceptor proteins	ACIAD1404	iscS	cysteine desulfurase used in synthesis of Fe-S cluster (tRNA 4-thiouridine sulfurtransferase )	COG1104	Aminotran_5	K04487
3NIQT	Amino acid permease	ACIAD1417	arcD	arginine/ornithine antiporter	COG0531	AA_permease_2	K03758
3NKTE	Uncharacterised MFS-type transporter YbfB	ACIAD1434	benK	benzoate transport protein (MFS superfamily)	COG0477	MFS_1	K05548
3NIX7	Alpha/beta hydrolase family	ACIAD1451	catD	3-oxoadipate enol-lactonase II (Beta-ketoadipate enol-lactone hydrolase II)	COG0596	Abhydrolase_1	K01055
3NKVT	Aminotransferase class-III	ACIAD1452		putative aminotransferase		Aminotran_3
3NJUF	Phosphorylcholine phosphatase	ACIAD1456		conserved hypothetical protein
3NKJN	Amino acid permease	ACIAD1458		putative transport protein	COG0531	AA_permease_2	K16238
3NM5S	Bacterial extracellular solute-binding proteins, family 5 Middle	ACIAD1506		putative dipeptide transport protein (ABC superfamily, peri_bind)	COG0747	SBP_bac_5	K02035
3NKYA	Bacterial extracellular solute-binding proteins, family 5 Middle	ACIAD1531		putative oligopeptide binding protein (ABC superfamily, peri_bind)(OppA)	COG0747	SBP_bac_5	K02035
3NSX0	Sugar (and other) transporter	ACIAD1541	citA	citrate-proton symporter (MFS superfamily)	COG0477	Sugar_tr	K03288
3NMA1	Cys/Met metabolism PLP-dependent enzyme	ACIAD1582		putative cysteine desulfurase 1 (Csd)	COG0520	Aminotran_5	K11717
3NMA0	Bacterial transferase hexapeptide (six repeats)	ACIAD1584	srpH	serine acetyltransferase	COG1045	Hexapep, SATase_N	K00640
1SDXT	NHase catalyzes the hydration of various nitrile compounds to the corresponding amides	ACIAD1615	nthB	nitrile hydratase subunit beta (NHase)		NHase_beta	K20807
3NJKD	Oxidizes proline to glutamate for use as a carbon and nitrogen source	ACIAD1646	putA	bifunctional protein [Includes: proline dehydrogenase (Proline oxidase); delta-1-pyrroline-5-carboxylate dehydrogenase (P5C dehydrogenase)]	COG1012, COG0506, COG4230	Aldedh, Pro_dh, Pro_dh-DNA_bdg	K13821
3NIFX	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family	ACIAD1649	putP	SSS family, major sodium/proline symporter	COG0591	SSF	K11928
3NIZF	Sugar (and other) transporter	ACIAD1651	pcaT	dicarboxylic acid transport protein; alpha-ketoglutarate permease (MFS superfamily)	COG0477	Sugar_tr	K02625
3NJTJ	Belongs to the cysteine synthase cystathionine beta- synthase family	ACIAD1662	cysK	subunit of cysteine synthase A and O-acetylserine sulfhydrolase A, PLP-dependent enzyme	COG0031	PALP	K01738
3NJE4	Sugar (and other) transporter	ACIAD1681	mucK	cis,cis-muconate transport protein (MFS superfamily)	COG0477	MFS_1, Sugar_tr	K08196
3NJ07	Major Facilitator Superfamily	ACIAD1685		putative transport protein (MFS superfamily)		MFS_1
3NJE4	Sugar (and other) transporter	ACIAD1694	dcaK	transport protein in catabolism of dicarboxylic acids (MFS superfamily)	COG0477	MFS_1	K08196
3NJ19	Major Facilitator Superfamily	ACIAD1698		putative transport protein (MFS superfamily)		MFS_1
3NIYK	Involved in the third step of the chorismate pathway, which leads to the biosynthesis of aromatic amino acids. Catalyzes the cis-dehydration of 3-dehydroquinate (DHQ) and introduces the first double bond of the aromatic ring to yield 3- dehydroshikimate	ACIAD1713	quiB	catabolic 3-dehydroquinate dehydratase (3- dehydroquinase)	COG0710	DHquinase_I	K03785
3NKGC	Major Facilitator Superfamily	ACIAD1727	hcaK	transporter of hydroxycinnamates (MFS superfamily)	COG0477	MFS_1, Sugar_tr	K05819
3NIYA	Catalyzes a trans-dehydration via an enolate intermediate	ACIAD1738	aroQ	3-dehydroquinate dehydratase, type II	COG0757	DHquinase_II	K03786
3NJZA	Fumarase C C-terminus	ACIAD1744	aspA	aspartate ammonia-lyase (aspartase)	COG1027	FumaraseC_C, Lyase_1	K01744
3NMA0	Bacterial transferase hexapeptide (six repeats)	ACIAD1763	srpH	serine acetyltransferase	COG1045	Hexapep	K00640
3NKAD	Periplasmic binding protein domain	ACIAD1765		putative branched-chain amino acid transport protein (ABC superfamily, peri_bind)	COG0683	Peripla_BP_5	K11959
3NJE3	Belongs to the binding-protein-dependent transport system permease family	ACIAD1766		putative branched-chain amino acid permease protein (ABC superfamily, membrane)	COG0559	BPD_transp_2	K11960
3NK6B	Belongs to the binding-protein-dependent transport system permease family	ACIAD1767		putative branched-chain amino acid permease protein (ABC superfamily, membrane)	COG4177	BPD_transp_2	K11961
3NM7M	ABC transporter	ACIAD1769		putative branched-chain amino acid transport protein (ABC superfamily, ATP_bind)	COG0410	ABC_tran	K11963
3NM8D	Methylene-tetrahydrofolate reductase C terminal	ACIAD1783		putative methylenetetrahydrofolate reductase	COG0685	MTHFR, MTHFR_C	K00297
3NMRY	Major Facilitator Superfamily	ACIAD1804		putative permease (MFS superfamily)		MFS_1
3NMHR	Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily	ACIAD1805		putative glyoxalase (dioxygenase domain)		Glyoxalase
3NM0W	Major Facilitator	ACIAD1815		putative benzoate transport protein (BenK-like)(MFS superfamily)	COG0477	MFS_1	K05548
3NIMG	Involved in the import of serine and threonine into the cell, with the concomitant import of sodium (symport system)	ACIAD1866	sstT	transporter, sodium-dicarboxylate symporter family	COG3633	SDF	K07862
3NK1N	MFS_1 like family	ACIAD1870		putative metabolite transporter (MFS superfamily)	COG0477	MFS_1_like	K05820
3NNJE	The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein	ACIAD1876	gcvH	glycine cleavage complex protein H, carrier of aminomethyl moiety via covalently bound lipoyl cofactor	COG0509	GCV_H	K02437
3NIQP	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)	ACIAD1878	aro	3-deoxy-D-arabinoheptulosonate-7-phosphate synthase (DAHP synthetase), tyrosine repressible	COG0722	DAHP_synth_1	K01626
3NJUW	EamA-like transporter family	ACIAD1896		putative permease (drug/metabolite transporter)		EamA
3NSZJ	EamA-like transporter family	ACIAD1924		putative integral membrane protein		EamA
3NJEJ	Belongs to the glutamate synthase family	ACIAD1934		putative glutamate synthase.		Glu_synthase
3NM7M	ABC transporter	ACIAD1937	braG	branched-chain amino acid transport protein (ABC superfamily, ATP_bind)	COG0410	ABC_tran	K01996
3NMUF	Periplasmic binding protein	ACIAD1938		conserved hypothetical protein; putative membrane protein	COG0683	Peripla_BP_6	K01999
3NK6B	Belongs to the binding-protein-dependent transport system permease family	ACIAD1939	braE	branched-chain amino acid transport protein (ABC superfamily, membrane)	COG0559	BPD_transp_2	K01998
3NJE3	Belongs to the binding-protein-dependent transport system permease family	ACIAD1940		putative branched-chain amino acid permease protein (ABC superfamily, membrane)	COG0559	BPD_transp_2	K01997
3NT1M	Branched-chain amino acid ATP-binding cassette transporter	ACIAD1941	braF	branched-chain amino acid transport protein (ABC superfamily, atp_bind)	COG0411	ABC_tran, BCA_ABC_TP_C	K01995
3NJYN	Major Facilitator Superfamily	ACIAD1971	smvA	methyl viologen resistance protein (MFS superfamily)	COG0477	MFS_1	K08167
3NT7G	LysE type translocator	ACIAD1981		putative transport protein	COG1280	LysE	K11250
3NJZD	Metallopeptidase family M24	ACIAD1987	map	methionine aminopeptidase	COG0024	Peptidase_M24	K01265
3NK3Z	FAD dependent oxidoreductase	ACIAD1998	dadA	D-amino acid dehydrogenase, small subunit	COG0665	DAO	K00285
3NINW	Domain of unknown function (DUF3458_C) ARM repeats	ACIAD2008	pepN	aminopeptidase N	COG0308	DUF3458, DUF3458_C, Peptidase_M1	K01256
3NNMG	5-carboxymethyl-2-hydroxymuconate isomerase	ACIAD2013		putative 5-carboxymethyl-2-hydroxymuconate delta isomerase	COG3232	CHMI	K01826
3NSUP	AzlC protein	ACIAD2023		putative branched-chain amino acid transport protein (AzlC)		AzlC
3NIIB	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system	ACIAD2028	aroC	chorismate synthase	COG0082	Chorismate_synt	K01736
3NIF3	ABC transporter	ACIAD2056	gltL	glutamate/aspartate transport protein (ABC superfamily, atp_bind)	COG1126	ABC_tran	K10004
3NSMP	Binding-protein-dependent transport system inner membrane component	ACIAD2059	gltJ	glutamate/aspartate transport protein (ABC superfamily, membrane)	COG0765	BPD_transp_1	K10003
3NK0B	Bacterial periplasmic substrate-binding proteins	ACIAD2061	gltI	glutamate/aspartate transport protein (ABC superfamily, peri_bind)	COG0834	SBP_bac_3	K10001
3NJ97	Aminotransferase class I and II	ACIAD2080	dapC	succinyldiaminopimelate transaminase	COG0436	Aminotran_1_2	K14267
3NP6X	LysE type translocator	ACIAD2083		putative amino acid efflux protein, putative threonine efflux protein		LysE
3NJ6Z	Aminotransferase	ACIAD2087	AlaA	glutamate-pyruvate aminotransferase	COG0436	Aminotran_1_2	K14260
3NKAE	Asparaginase	ACIAD2088	aspQ	glutaminase-asparaginase	COG0252	Asparaginase	K05597
3NJAM	Serine acetyltransferase, N-terminal	ACIAD2091	cysE	serine acetyltransferase	COG1045	Hexapep, SATase_N	K00640
3NK66	EamA-like transporter family	ACIAD2115		hypothetical protein
3NSY8	Sugar (and other) transporter	ACIAD2122		putative multidrug resistance protein (MFS superfamily) (BfnC)		MFS_1
3NJKU	LysE type translocator	ACIAD2144		putative threonine efflux protein		LysE
3NJF0	Domain of unknown function (DUF3488)	ACIAD2201		conserved hypothetical protein; putative membrane protein	COG1305	DUF3488, Transglut_core	K22452
3NN4K	Catalyzes the conversion of hemimercaptal, formed from methylglyoxal and glutathione, to S-lactoylglutathione	ACIAD2213	gloA	lactoylglutathione lyase	COG0346	Glyoxalase	K01759
3NKXC	Peptidase family M20/M25/M40	ACIAD2220	pepD	aminoacyl-histidine dipeptidase (peptidase D)	COG2195	M20_dimer, Peptidase_M20	K01270
3NK5W	Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3- phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate	ACIAD2222		bifunctional protein [Includes: putative prephenate or cyclohexadienyl dehydrogenase; 3-phosphoshikimate 1-carboxyvinyltransferase (5- enolpyruvylshikimate-3-phosphate synthase) (EPSP synthase) (EPSPS) (AroA)]	COG0287, COG0128	EPSP_synthase, PDH	K00220, K00800
3NJBR	chorismate mutase	ACIAD2223	pheA	bifuctional protein [Includes: chorismate mutase P; prephenate dehydratase ]	COG0077, COG1605	ACT, CM_2, PDT	K14170
3NJHX	Glycosyl transferase family, helical bundle domain	ACIAD2229		putative transferase		Glycos_trans_3N, Glycos_transf_3
3NJSY	Asp/Glu/Hydantoin racemase	ACIAD2248	hyu	hydantoin-racemase		Asp_Glu_race	K16841
3NJDM	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism	ACIAD2255	glyA	serine hydroxymethyltransferase	COG0112	SHMT	K00600
3NK8T	Methionine aminopeptidase	ACIAD2271	map	methionine aminopeptidase	COG0024	Peptidase_M24	K01265
3NJYI	Sugar (and other) transporter	ACIAD2280	proP	glycine/betaine transporter (MFS superfamily)	COG0477	Osmo_CC, Sugar_tr	K03762
3NK2Z	Methylenetetrahydrofolate reductase	ACIAD2283	metF	5,10-methylenetetrahydrofolate reductase	COG0685	MTHFR	K00297
3NIQC	Catalyzes the formation of L-homocysteine from O- succinyl-L-homoserine (OSHS) and hydrogen sulfide	ACIAD2314	metZ	o-acylhomoserine sulfhydrylase	COG0626	Cys_Met_Meta_PP	K10764
3NIZR	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)	ACIAD2330	aro	phospho-2-dehydro-3-deoxyheptonate aldolase	COG0722	DAHP_synth_1	K01626
3NK0M	AzlC protein	ACIAD2343		conserved hypothetical protein; putative branched-chain amino acid permease (azaleucine resistance)		AzlC
3NKNC	Sugar (and other) transporter	ACIAD2385		putative permease (MFS superfamily)	COG2814	MFS_1, Sugar_tr	K19577
3NIXV	Transmembrane secretion effector	ACIAD2404		putative permease (MFS superfamily)		MFS_1
3NJ0G	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids	ACIAD2434	alr	alanine racemase 1, biosynthetic	COG0787	Ala_racemase_C, Ala_racemase_N	K01775
3NJC3	Bacterial transglutaminase-like N-terminal region	ACIAD2436		conserved hypothetical protein; putative transglutaminase		Bact_transglu_N, Transglut_core
3NJCF	glutamine synthetase	ACIAD2458	glnA	glutamine synthetase	COG0174	Gln-synt_C, Gln-synt_N	K01915
3NIZ1	component II	ACIAD2461	trpG	bifunctional protein:[Includes: para-aminobenzoate synthase glutamine amidotransferase component II (ADC synthase); anthranilate synthase component II]	COG0512	GATase	K01658
3NIQH	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)	ACIAD2462	trpD	anthranilate phosphoribosyltransferase	COG0547	Glycos_trans_3N, Glycos_transf_3	K00766
3NJGD	Belongs to the TrpC family	ACIAD2463	trpC	indole-3-glycerol phosphate synthase (IGPS)	COG0134	IGPS	K01609
3NKC9	Membrane dipeptidase (Peptidase family M19)	ACIAD2508	acdP	Zn-dependent dipeptidase		Peptidase_M19
3NISZ	COG2610 H gluconate symporter and related permeases	ACIAD2510		putative D-beta-hydroxybutyrate permease		GntP_permease
3NJIA	Allophanate hydrolase subunit 2	ACIAD2518	pxpC	putative L-5-oxoprolinase (ATP-dependent) subunit C		CT_A_B, CT_C_D
3NR46	Bacterial extracellular solute-binding protein	ACIAD2524		putative substrate binding protein (ABC superfamily, peri_bind)	COG0687	SBP_bac_6	K02055
3NJEJ	Belongs to the glutamate synthase family	ACIAD2525	mgsC	putative N-methyl glutamate synthase subunit C		Glu_synthase	K22083
3NMPF	Glutamine synthetase, catalytic domain	ACIAD2528	gmaS	putative gamma glutamylmethylamide synthetase	COG0174	Gln-synt_C	K01915
3NKD6	Major Facilitator Superfamily	ACIAD2531		putative sugar efflux transporter (MFS superfamily)	COG2814	MFS_1	K03445
3NIH1	Sugar (and other) transporter	ACIAD2535		putative transporter (MFS superfamily)		Sugar_tr
3NN7E	Sarcosine oxidase, gamma subunit family	ACIAD2549	mgdD	putative N-methyl glutamate dehydrogenase/oxidoreductase subunit D	COG4583	SoxG	K00305
3NM8N	Glycine cleavage T-protein C-terminal barrel domain	ACIAD2550	mgdC	putative N-methyl glutamate dehydrogenase/oxidoreductase subunit C	COG0446	Fer2_4, GCV_T, GCV_T_C, Pyr_redox_2	K00302
3NP1A	Sarcosine oxidase, delta subunit family	ACIAD2551	mgdB	putative N-methyl glutamate dehydrogenase/oxidoreductase subunit B	COG4311	SoxD	K00304
3NMHX	FAD dependent oxidoreductase	ACIAD2552	mgdA	putative N-methyl glutamate dehydrogenase/oxidoreductase subunit A	COG0665	DAO	K00303
3NJEE	haloacid dehalogenase-like hydrolase	ACIAD2559		conserved hypothetical protein; putative phosphoserine phosphatase		HAD
3NIWZ	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate	ACIAD2560	proB	gamma-glutamyl kinase	COG0263	AA_kinase, PUA	K00931
3NKE8	DegT/DnrJ/EryC1/StrS aminotransferase family	ACIAD2574	aspC	aspartate aminotransferase A	COG0436	Aminotran_1_2	K00812
3NIK0	Branched-chain amino acid aminotransferase 4-amino-4-deoxychorismate lyase	ACIAD2590	pabC	4-amino-4-deoxychorismate lyase	COG0115	Aminotran_4	K02619
3NINN	Belongs to the transferase hexapeptide repeat family	ACIAD2599	dapD	2,3,4,5-tetrahydropyridine-2-carboxylate N-succinyltransferase	COG2171	Hexapep, Hexapep_2, THDPS_N_2	K00674
3NIHX	Uncharacterised MFS-type transporter YbfB	ACIAD2610		putative transport protein (MFS superfamily)		MFS_4
3NK0I	EamA-like transporter family	ACIAD2643		conserved hypothetical protein; putative membrane protein		EamA
3NKGT	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine	ACIAD2647	serC	3-phosphoserine aminotransferase	COG1932	Aminotran_5	K00831
3NIIS	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan	ACIAD2659	dapF	diaminopimelate epimerase	COG0253	DAP_epimerase	K01778
3NJND	Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine	ACIAD2660	lysA	diaminopimelate decarboxylase	COG0019	Orn_Arg_deC_N, Orn_DAP_Arg_deC	K01586
3NJUE	Amino acid permease	ACIAD2662	cycA	D-alanine/D-serine/glycine transport protein (APC family)	COG1113	AA_permease	K11737
3NIYW	Belongs to the Glu Leu Phe Val dehydrogenases family	ACIAD2680	gdh	glutamate dehydrogenase (NAD(P)+) oxidoreductase protein	COG0334	ELFV_dehydrog, ELFV_dehydrog_N	K00261
3NK22	LysE type translocator	ACIAD2743		putative amino acid efflux transmembrane protein		LysE
3NJJ3	EamA-like transporter family	ACIAD2746		conserved hypothetical protein; putative membrane protein		EamA
1SAEH	Protein of unknown function (DUF2569)	ACIAD2752		hypothetical protein; putative membrane protein		DUF2569
3NJ30	Acetyl-coenzyme A transporter 1	ACIAD2763	fbsO	putative transport protein (MFS superfamily)		MFS_1
3NK2X	Belongs to the Orn Lys Arg decarboxylase class-II family	ACIAD2768	fbsJ	putative ornithine decarboxylase	COG1982	Orn_Arg_deC_N, Orn_DAP_Arg_deC	K01581
3NSNV	FAD dependent oxidoreductase	ACIAD2790		putative oxidoreductase		DAO
3NM36	HMGL-like	ACIAD2820		putative hydroxymethylglutaryl-CoA lyase	COG0119	HMGL-like	K01640
3NIMK	Amino acid permease	ACIAD2930		putative amino acid transport protein (APC family)		AA_permease
3NJ30	Acetyl-coenzyme A transporter 1	ACIAD2963		putative transporter (MFS superfamily)		Acatn
3NJKE	Amino acid permease	ACIAD2969	aroP	aromatic amino acid transporter (APC family)	COG0833, COG1113	AA_permease	K03293
3NM4B	LysE type translocator	ACIAD2980		conserved hypothetical protein; putative amino acid efflux transmembrane protein		LysE
3NNHY	Glyoxalase-like domain	ACIAD2992		conserved hypothetical protein
3NIYY	Sugar (and other) transporter	ACIAD2997		putative transport protein (MFS superfamily)		Sugar_tr
3NJW4	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline	ACIAD3032	proC	pyrroline-5-carboxylate reductase	COG0345	F420_oxidored, P5CR_dimer	K00286
3NJMG	Transmembrane secretion effector	ACIAD3048		putative transporter		MFS_3
3NJVZ	Belongs to the cysteine synthase cystathionine beta- synthase family	ACIAD3071	cysM	cysteine synthase B (O-acetylserine sulfhydrolase B)	COG0031	PALP	K12339
3NKS2	EamA-like transporter family	ACIAD3081		putative membrane protein		EamA
3NJ19	Major Facilitator Superfamily	ACIAD3084		putative transport protein (MFS superfamily)		MFS_1
3NK7Y	Acetolactate synthase small	ACIAD3103	ilvH	acetolactate synthase isozyme III, small subunit	COG0440	ACT_5, ALS_ss_C	K01653
3NJ7R	Belongs to the UPF0758 family	ACIAD3126	radC	DNA repair protein, associated with replication forks	COG2003	RadC	K03630
3NP9X	Protein of unknown function (DUF2789)	ACIAD3153		conserved hypothetical protein		DUF2789
3NTET	LysE type translocator	ACIAD3166		putative amino-acid efflux transmembrane protein		LysE
3NJDF	Sugar (and other) transporter	ACIAD3170		putative transporter (MFS superfamily)	COG0477	MFS_1	K08224
3NJ7Q	Peptidase family M3	ACIAD3182	prlC	oligopeptidase A	COG0339	Peptidase_M3	K01414
3NJ2T	Cys/Met metabolism PLP-dependent enzyme	ACIAD3222		putative cystathionine beta-lyase, PLP-dependent (beta-cystathionase) (MetC)	COG0626	Cys_Met_Meta_PP	K01760
3NMU0	EamA-like transporter family	ACIAD3273		putative transporter		EamA
3NJNY	Sugar (and other) transporter	ACIAD3292	mdfA	multidrug/chloramphenicol efflux transport protein (MFS superfamily)	COG0477	MFS_1	K08160
3NINV	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family	ACIAD3302	serA	D-3-phosphoglycerate dehydrogenase	COG0111	2-Hacid_dh, 2-Hacid_dh_C	K00058
3NPB3	Orn/Lys/Arg decarboxylase, C-terminal domain	ACIAD3341		putative arginine/lysine/ornithine decarboxylase	COG1982	OKR_DC_1, OKR_DC_1_C	K01584
3NIS3	glutamate synthase	ACIAD3349	gltD	glutamate synthase small chain	COG0493	Fer4_20, Pyr_redox_2	K00266
3NJ2V	Glutamate synthase central domain	ACIAD3350	gltB	glutamate synthase large chain precursor	COG0067, COG0069, COG0070	GATase_2, GXGXG, Glu_syn_central, Glu_synthase	K00265
3NKDH	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)	ACIAD3353	aroB	3-dehydroquinate synthase	COG0337	DHQ_synthase	K01735
3NK4W	Cys/Met metabolism PLP-dependent enzyme	ACIAD3382	metY	homocysteine synthase	COG2873	Cys_Met_Meta_PP	K01740
3NK7V	imidazoleglycerol-phosphate dehydratase	ACIAD3395	hisB	imidazoleglycerol-phosphate dehydratase	COG0131	IGPD	K01693
3NITT	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR	ACIAD3396	hisH	imidazole glycerol phosphate synthetase, glutamine amidotransferase subunit	COG0118	GATase	K02501
3NK1S	1-(5-phosphoribosyl)-5- (5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase	ACIAD3398	hisA	phosphoribosylformimino-5-aminoimidazole carboxamide isomerase	COG0106	His_biosynth	K01814
3NIUS	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit	ACIAD3404	hisF	imidazole glycerol phosphate synthase, cyclase subunit	COG0107	His_biosynth	K02500
1RR40	IrrE N-terminal-like domain	ACIAD3429		putative peptidase_M78 domain-containing protein		Peptidase_M78
3NJXN	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family	ACIAD3446	gabT	4-aminobutyrate aminotransferase, PLP-dependent	COG0160, COG4992	Aminotran_3	K00823
3NSN1	Amino acid permease	ACIAD3448	gabP	gamma-aminobutyrate permease	COG1113	AA_permease	K11735
3NJ46	Sugar (and other) transporter	ACIAD3450		putative transport protein (MFS superfamily)		MFS_1
3NJH2	Bacterial periplasmic substrate-binding proteins	ACIAD3484		putative arginine/ornithine binding protein (ABC superfamily, peri_bind)(artI, aotJ)	COG0834	SBP_bac_3	K02030
3NM72	Belongs to the bacterial solute-binding protein 3 family	ACIAD3487		putative amino acid binding protein (ABC superfamily, peri_bind)	COG0834	SBP_bac_3	K02030
3NM70	Belongs to the peptidase M20A family. ArgE subfamily	ACIAD3489	argE	N-acetylornithine deacetylase	COG0624	M20_dimer, Peptidase_M20	K01438
3NITP	Cobalamin-independent synthase, Catalytic domain	ACIAD3523	metE	5-methyltetrahydropteroyltriglutamate- homocysteine methyltransferase	COG0620	Meth_synt_2	K00549
3NJU6	Cys/Met metabolism PLP-dependent enzyme	ACIAD3553		putative methionine aminotransferase, PLP-dependent	COG0436	Aminotran_1_2	K14287
3NJTN	phosphoserine phosphatase	ACIAD3567	serB	phosphoserine phosphatase	COG0560	ACT_6, HAD	K01079
3NKC2	Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily	ACIAD3579		fragment of putative homogentisate 1,2-dioxygenase		Glyoxalase
3NK9V	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)	ACIAD3585	dapA	4-hydroxy-tetrahydrodipicolinate synthase	COG0329	DHDPS	K01714
3NMNW	Belongs to the bacterial solute-binding protein 3 family	ACIAD3588		putative amino acid-binding protein (ABC superfamily, peri_bind)	COG0834	SBP_bac_3	K02030
3NTMY	ATPases associated with a variety of cellular activities	ACIAD3592		putative amino acid transport protein (ABC superfamily, ATP_bind)	COG1126	ABC_tran	K02028
COG0346	lactoylglutathione lyase activity	ACIAD3609		hypothetical protein
COG0346	lactoylglutathione lyase activity	ACIAD3609		hypothetical protein
3NIRP	Major Facilitator Superfamily	ACIAD3617		putative transport protein (MFS superfamily)	COG2814	MFS_1	K19577
3NIYU	Catalyzes the conversion of 4-hydroxy- tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate	ACIAD3619	dapB	4-hydroxy-tetrahydrodipicolinate reductase	COG0289	DapB_C, DapB_N	K00215
3NJMA	Belongs to the IlvD Edd family	ACIAD3636		putative dihydroxyacid dehydratase (ilvD-like)	COG0129	ILVD_EDD	K01687
3NIHI	Major Facilitator Superfamily	ACIAD3678		putative multidrug resistence transporter (MFS superfamily)	COG0477	MFS_1	K03446

3NIZC

Belongs to the acetyltransferase family. ArgA subfamily

ACIAD0039

argA

N-alpha-acetylglutamate synthase (amino-acid acetyltransferase)

COG0548, COG1246

AA_kinase, Acetyltransf_1

K14682

3NKI3

Belongs to the DegT DnrJ EryC1 family

ACIAD0095

per

perosamine synthetase (WeeJ)

DegT_DnrJ_EryC1

3NJRT

Aminotransferase class I and II

ACIAD0112

tyrB

tyrosine aminotransferase, tyrosine repressible, PLP-dependent

COG1448

Aminotran_1_2

K00832

3NJK5

Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids

ACIAD0116

dadX

alanine racemase 2, PLP-binding, catabolic

COG0787

Ala_racemase_C, Ala_racemase_N

K01775

3NJUE

Amino acid permease

ACIAD0118

cycA

APC family, D-serine/D-alanine/glycine transport protein

COG1113

AA_permease

K11737

3NJPE

EamA-like transporter family

ACIAD0125

conserved hypothetical protein; putative membrane protein

EamA

3NIFI

Belongs to the DapA family

ACIAD0130

kdgD

5-dehydro-4-deoxyglucarate dehydratase (5-keto-4-deoxy- glucarate dehydratase)

COG0329

DHDPS

K01707

3NJWA

lysine exporter protein (LysE YggA)

ACIAD0147

putative amino acid transporter

LysE

3NJKK

EamA-like transporter family

ACIAD0161

putative transporter

EamA

3NIVK

LysE type translocator

ACIAD0173

rhtB

homoserine/homoserine lactone efflux protein

COG1280

LysE

K05834

3NSWZ

Major Facilitator Superfamily

ACIAD0195

putative transporter (MFS superfamily)

MFS_1

3NIXW

EamA-like transporter family

ACIAD0197

putative membrane protein

EamA

3NKDF

Sugar (and other) transporter

ACIAD0223

shiA

shikimate and dehydroshikimate transport protein (MFS superfamily)

COG0477

MFS_1

K08172

3NKDC

Sugar (and other) transporter

ACIAD0233

niaP

niacin transporer

COG0477

MFS_1

K08369

3NJ24

Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides

ACIAD0253

pepA

aminopeptidase A

COG0260

Peptidase_M17, Peptidase_M17_N

K01255

3NIF7

Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine

ACIAD0263

thrC

threonine synthase, pyridoxal-5'-phosphate-dependent enzyme

COG0498

PALP

K01733

3NKC8

homoserine dehydrogenase

ACIAD0264

hom

homoserine dehydrogenase

COG0460

ACT, Homoserine_dh, NAD_binding_3

K00003

3NJHZ

argininosuccinate lyase

ACIAD0283

argH

argininosuccinate lyase (Arginosuccinase) (ASAL)

COG0165

ASL_C2, Lyase_1

K01755

3NIJW

Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia

ACIAD0297

trpE

anthranilate synthase component I

COG0147

Anth_synt_I_N, Chorismate_bind

K01657

3NJPS

EamA-like transporter family

ACIAD0358

putative tranporter

EamA

3NK5C

belongs to the PRA-CH family

ACIAD0380

hisIE

bifunctional protein [Includes: phosphoribosyl-AMP cyclohydrolase; phosphoribosyl-ATP pyrophosphatase]

COG0139, COG0140

PRA-CH, PRA-PH

K11755

3NSX0

Sugar (and other) transporter

ACIAD0395

citA

citrate-proton symporter (Citrate transporter) (Citrate carrier protein) (Citrate utilization determinant) (Citrate utilization protein A)

MFS_1

3NJ6E

Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)

ACIAD0418

aroE

dehydroshikimate reductase, NAD(P)-binding

COG0169

Shikimate_DH, Shikimate_dh_N

K00014

3NITK

haloacid dehalogenase-like hydrolase

ACIAD0456

hisK

histidinol-phosphatase

HAD

3NJM4

Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate

ACIAD0463

leuC

3-isopropylmalate dehydratase (isomerase), subunit with LeuD

COG0065

Aconitase

K01703

3NK10

Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate

ACIAD0466

leuD

3-isopropylmalate isomerase (dehydratase), subunit with LeuC

COG0066

Aconitase_C

K01704

3NK2W

Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate

ACIAD0469

leuB

3-isopropylmalate dehydrogenase

Iso_dh

Asparaginase

putative L-asparaginase I (AnsA)

COG0252

Asparaginase

K01424

3NJ2Q

Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate

ACIAD0479

asd

aspartate-semialdehyde dehydrogenase, NAD(P)-binding

COG0136

Semialdhyde_dh, Semialdhyde_dhC

K00133

3NT7H

LysE type translocator

ACIAD0486

putative transporter protein

LysE

3NK6R

Transfers a succinyl group from succinyl-CoA to L- homoserine, forming succinyl-L-homoserine

ACIAD0529

metXS

Homoserine O-succinyltransferase

COG2021

Abhydrolase_1

K00641

3NJF8

Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)

ACIAD0530

leuA

2-isopropylmalate synthase (Alpha-isopropylmalate synthase) (Alpha-IPM synthetase)

COG0119

HMGL-like, LeuA_dimer

K01649

3NKHE

Belongs to the IlvD Edd family

ACIAD0542

edd

phosphogluconate dehydratase (6-phosphogluconate dehydratase)

ILVD_EDD

GntP family permease

gntT

high-affinity gluconate permease (GntP family)

COG2610

GntP_permease

K03299

3NJAC

Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate

ACIAD0547

proA

gamma-glutamyl phosphate reductase (GPR) (Glutamate-5- semialdehyde dehydrogenase) (Glutamyl-gamma-semialdehyde dehydrogenase) (GSA dehydrogenase)

COG0014

Aldedh

K00147

3NJM0

histidine ammonia-lyase activity

ACIAD0574

hutH

histidine ammonia-lyase protein (Histidase)

COG2986

Lyase_aromatic

K01745

3NK5G

Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family

ACIAD0597

ilvE

branched-chain amino acid transferase

COG0115

Aminotran_4

K00826

3NIWQ

Belongs to the TrpF family

ACIAD0635

trpF

N-(5'-phosphoribosyl)anthranilate isomerase (PRAI)

COG0135

PRAI

K01817

3NJAP

The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine

ACIAD0636

trpB

tryptophan synthase beta chain

COG0133

PALP

K01696

3NKMT

The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3- phosphate

ACIAD0642

trpA

tryptophan synthase alpha chain

COG0159

Trp_syntA

K01695

3NJGF

Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate

ACIAD0650

argJ

bifunctional protein [Includes: glutamate N-acetyltransferase (Ornithine acetyltransferase) (Ornithine transacetylase) (OATASE); amino-acid acetyltransferase (N-acetylglutamate synthase) (AGS)]

COG1364

ArgJ

K00620

3NIG8

Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity

ACIAD0661

hisG

ATP-phosphoribosyltransferase

COG0040

HisG

K00765

3NJH3

Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine

ACIAD0663

hisD

Histidinol dehydrogenase (HDH)

COG0141

Histidinol_dh

K00013

3NIR7

Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily

ACIAD0664

hisC

histidinol-phosphate aminotransferase

COG0079

Aminotran_1_2

K00817

3NIKM

chorismate binding enzyme

ACIAD0665

pabB

p-aminobenzoate synthetase

Chorismate_bind

Amino acid permease

lysP

lysine-specific permease

COG0833

AA_permease

K11733

3NK9X

Pyridoxal-phosphate dependent enzyme

ACIAD0753

putative D-cysteine desulfhydrase (DcyD)

COG2515

PALP

K05396

3NTGK

haloacid dehalogenase-like hydrolase

ACIAD0754

Putative phosphoserine phosphatase

HAD

3NKWK

Major facilitator superfamily

ACIAD0756

putative transporter (MFS superfamily)

MFS_1

3NTES

LysE type translocator

ACIAD0759

putative threonine efflux protein (RhtC)

LysE

3NJKU

LysE type translocator

ACIAD0775

conserved hypothetical protein; putative membrane protein

LysE

3NIXJ

Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls

ACIAD0791

dapE

succinyl-diaminopimelate desuccinylase

COG0624

M20_dimer, Peptidase_M20

K01439

3NJ83

Sugar (and other) transporter

ACIAD0802

putative bicyclomycin/multidrug transport protein (MFS superfamily)

COG0477

MFS_1

K07552

3NIJ7

Sodium:alanine symporter family

ACIAD0805

putative amino-acid transport protein

COG1115

Na_Ala_symp

K03310

3NII6

Reduction of activated sulfate into sulfite

ACIAD0833

putative 5'-adenylylsulfate reductase (APS reductase) (cysH-like)

COG0175

PAPS_reduct

K00390

3NJXD

haloacid dehalogenase-like hydrolase

ACIAD0834

putative homoserine kinase (ThrH)

COG0560

Hydrolase

K02203

3NJNE

8-amino-7-oxononanoate synthase

ACIAD0857

bioF

8-amino-7-oxononanoate synthase

Aminotran_1_2

Pfam:DUF955

conserved hypothetical protein ; putative phage related protein

Mrr_cat, Peptidase_M78

3NJA7

Belongs to the acetylglutamate kinase family. ArgB subfamily

ACIAD0903

argB

acetylglutamate kinase

COG0548

AA_kinase

K00930

3NM3M

Transglutaminase/protease-like homologues

ACIAD0915

conserved hypothetical protein; putative transglutaminase-like enzyme

Transglut_core

3NK8N

FAD dependent oxidoreductase

ACIAD0922

putative D-amino acid oxidase

COG0665

DAO

K03153

3NJ0E

Sugar (and other) transporter

ACIAD0927

emrB

multidrug resistance transmembrane protein (MFS superfamily)

COG0477

MFS_1

K03446

3NK4G

Phosphoribosyl synthetase-associated domain

ACIAD0964

prs

ribose-phosphate pyrophosphokinase (Phosphoribosyl pyrophosphate synthetase)

COG0462

Pribosyltran

K00948

3NMPW

Uncharacterised MFS-type transporter YbfB

ACIAD0982

vanK

vanillate transporter (MFS superfamily)

MFS_1

3NKI2

Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily

ACIAD0990

putative dioxygenase

Glyoxalase

3NIP9

Thiamine pyrophosphate enzyme, central domain

ACIAD0999

putative acetolactate synthase (IlvB-like)

COG0028

TPP_enzyme_C, TPP_enzyme_M, TPP_enzyme_N

K01652

3NMA8

Transmembrane secretion effector

ACIAD1006

putative permease (MFS superfamily)

MFS_3

3NK8U

Involved in the biosynthesis of the osmoprotectant glycine betaine. Catalyzes the oxidation of choline to betaine aldehyde and betaine aldehyde to glycine betaine at the same rate

ACIAD1008

betA

choline dehydrogenase, a flavoprotein

COG2303

GMC_oxred_C, GMC_oxred_N

K00108

3NKBG

Major facilitator superfamily

ACIAD1036

putative permease (MFS superfamily)

MFS_1

3NMCU

Belongs to the glutaminase family

putative glutaminase

Glutaminase

B12 binding domain

metH

methionine synthase (B12-dependent homocysteine-N5-methyltetrahydrofolate transmethylase, repressor of metE and metF)

COG1410, COG0646

B12-binding, B12-binding_2, Met_synt_B12, Pterin_bind, S-methyl_trans

K00548

3NKT6

Belongs to the serine threonine dehydratase family. DsdA subfamily

ACIAD1048

dsdA

D-serine deaminase (dehydratase)

COG3048

PALP

K01753

3NJ8U

GDSL-like Lipase/Acylhydrolase family

ACIAD1057

tesA

multifunctional protein [Includes: acyl-CoA thioesterase I; protease I; lysophospholipaseL(I)]

COG2755

Lipase_GDSL_2

K10804

3NKEF

Serine aminopeptidase, S33

ACIAD1064

putative hydrolase (EstB)

Abhydrolase_1

3NNWE

Belongs to the urease gamma subunit family

ACIAD1089

ureA

urease gamma subunit

COG0831

Urease_gamma

K01430

3NP3Z

Belongs to the urease beta subunit family

ACIAD1090

ureB

urease beta subunit

COG0832

Urease_beta

K01429

3NINC

Belongs to the metallo-dependent hydrolases superfamily. Urease alpha subunit family

ACIAD1091

ureC

urease alpha subunit

COG0804

Amidohydro_1, Urease_alpha

K01428

3NITF

Belongs to the Glu Leu Phe Val dehydrogenases family

ACIAD1110

gdhA

glutamate dehydrogenase, NADP-specific

COG0334

ELFV_dehydrog, ELFV_dehydrog_N

K00262

3NJMZ

Belongs to the peptidase M24B family

ACIAD1126

pepP

aminopeptidase P

COG0006

AMP_N, Peptidase_M24

K01262

3NJZZ

Bacterial extracellular solute-binding proteins, family 5 Middle

ACIAD1139

putative oligopeptide transport protein (ABC superfamily, peri_bind)

COG4166

SBP_bac_5

K13893

3NTAU

Belongs to the peptidase S1B family

ACIAD1144

conserved hypothetical protein

3NTK8

Belongs to the peptidase S1B family

ACIAD1145

conserved hypothetical protein

3NJ12

amino acid

ACIAD1147

putative APC family, S-methylmethionine transporter (MmuP)

COG0833

AA_permease

K16235

3NKG1

Belongs to the argininosuccinate synthase family. Type

ACIAD1151

argG

argininosuccinate synthetase

COG0137

Arginosuc_synth

K01940

3NKKR

EamA-like transporter family

ACIAD1154

putative transport protein

EamA

3NM0M

Catalyzes the conversion of urocanate to 4-imidazolone- 5-propionate

ACIAD1166

fragment of urocanate hydratase (Urocanase) (Imidazolonepropionate hydrolase) (HutU)

Urocanase, Urocanase_C, Urocanase_N

3NJM0

histidine ammonia-lyase activity

ACIAD1167

fragment of Histidine ammonia-lyase (Histidase) (HutH)

Lyase_aromatic

Amino acid permease

putative histidine transport protein (APC family)

COG1113

AA_permease

K16234

3NJKQ

Catalyzes the conversion of N-formimidoyl-L-glutamate to L-glutamate and formamide

ACIAD1169

fragment of formimidoylglutamase (Formiminoglutamase) (Formiminoglutamate hydrolase) (HutG)

Arginase

3NJ5V

Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family

ACIAD1210

dat

diaminobutyrate--2-oxoglutarate aminotransferase (L- diaminobutyric acid transaminase) (Diaminobutyrate transaminase) (DABA aminotransferase) (DABA-AT) (L-2,4-diaminobutyrate:2-ketoglutarate 4- aminotransferase)

COG0160, COG4992

Aminotran_3

K00836

3NIHU

Pyridoxal-dependent decarboxylase conserved domain

ACIAD1211

ddc

L-2,4-diaminobutyrate decarboxylase

COG0076

Pyridoxal_deC

K13745

3NKVR

acetylornithine aminotransferase

ACIAD1231

argD

acetylornithine aminotransferase

COG0160, COG4992

Aminotran_3

K00821

3NKCG

Belongs to the aspartokinase family

ACIAD1252

lysC

aspartate kinase

COG0527

AA_kinase, ACT, ACT_7

K00928

3NM0B

Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine

ACIAD1257

hisZ

ATP phosphoribosyltransferase

COG3705

tRNA-synt_His

K02502

3NJMA

Belongs to the IlvD Edd family

ACIAD1266

ilvD

dihydroxy-acid dehydratase

ILVD_EDD

Amino acid permease

putative amino acid transporter

AA_permease_2

3NKVR

acetylornithine aminotransferase

ACIAD1284

aruC

Succinylornithine transaminase

COG0160, COG4992

Aminotran_3

K00840

3NJDN

Arginine N-succinyltransferase beta subunit

ACIAD1286

aruG

arginine/ornithine succinyltransferase AII subunit

COG3138

AstA

K00673

3NKQD

Catalyzes the hydrolysis of N(2)-succinylarginine into N(2)-succinylornithine, ammonia and CO(2)

ACIAD1288

aruB

succinylarginine dihydrolase

COG3724

AstB

K01484

3NK6H

Belongs to the AspA AstE family. Succinylglutamate desuccinylase subfamily

ACIAD1289

aruE

succinylglutamate desuccinylase

COG2988

AstE_AspA

K05526

3NM72

Belongs to the bacterial solute-binding protein 3 family

ACIAD1297

putative amino acid transporter (ABC superfamily, peri_bind)

SBP_bac_3

Arginase family

gbuA

guanidinobutyrase

Arginase

Amino acid permease

aroP

aromatic amino acid transporter (APC family)

COG1113

AA_permease

K11734

3NJ5D

Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA

ACIAD1357

ilvA

Threonine dehydratase biosynthetic (Threonine deaminase)

COG1171

PALP, Thr_dehydrat_C

K01754

3NJA9

Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde

ACIAD1360

argC

N-acetyl-gamma-glutamyl-phosphate reductase

COG0002

Semialdhyde_dh, Semialdhyde_dhC

K00145

3NIKC

Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline

ACIAD1366

argF

ornithine carbamoyltransferase

COG0078

OTCace, OTCace_N

K00611

3NKJK

Master enzyme that delivers sulfur to a number of partners involved in Fe-S cluster assembly, tRNA modification or cofactor biosynthesis. Catalyzes the removal of elemental sulfur atoms from cysteine to produce alanine. Functions as a sulfur delivery protein for Fe-S cluster synthesis onto IscU, an Fe-S scaffold assembly protein, as well as other S acceptor proteins

ACIAD1404

iscS

cysteine desulfurase used in synthesis of Fe-S cluster (tRNA 4-thiouridine sulfurtransferase )

Aminotran_5

Amino acid permease

arcD

arginine/ornithine antiporter

COG0531

AA_permease_2

K03758

3NKTE

Uncharacterised MFS-type transporter YbfB

ACIAD1434

benK

benzoate transport protein (MFS superfamily)

COG0477

MFS_1

K05548

3NIX7

Alpha/beta hydrolase family

ACIAD1451

catD

3-oxoadipate enol-lactonase II (Beta-ketoadipate enol-lactone hydrolase II)

COG0596

Abhydrolase_1

K01055

3NKVT

Aminotransferase class-III

ACIAD1452

putative aminotransferase

Aminotran_3

3NJUF

Phosphorylcholine phosphatase

ACIAD1456

conserved hypothetical protein

3NKJN

Amino acid permease

ACIAD1458

putative transport protein

COG0531

AA_permease_2

K16238

3NM5S

Bacterial extracellular solute-binding proteins, family 5 Middle

ACIAD1506

putative dipeptide transport protein (ABC superfamily, peri_bind)

COG0747

SBP_bac_5

K02035

3NKYA

Bacterial extracellular solute-binding proteins, family 5 Middle

ACIAD1531

putative oligopeptide binding protein (ABC superfamily, peri_bind)(OppA)

COG0747

SBP_bac_5

K02035

3NSX0

Sugar (and other) transporter

ACIAD1541

citA

citrate-proton symporter (MFS superfamily)

COG0477

Sugar_tr

K03288

3NMA1

Cys/Met metabolism PLP-dependent enzyme

ACIAD1582

putative cysteine desulfurase 1 (Csd)

COG0520

Aminotran_5

K11717

3NMA0

Bacterial transferase hexapeptide (six repeats)

ACIAD1584

srpH

serine acetyltransferase

COG1045

Hexapep, SATase_N

K00640

1SDXT

NHase catalyzes the hydration of various nitrile compounds to the corresponding amides

ACIAD1615

nthB

nitrile hydratase subunit beta (NHase)

NHase_beta

K20807

3NJKD

Oxidizes proline to glutamate for use as a carbon and nitrogen source

ACIAD1646

putA

bifunctional protein [Includes: proline dehydrogenase (Proline oxidase); delta-1-pyrroline-5-carboxylate dehydrogenase (P5C dehydrogenase)]

COG1012, COG0506, COG4230

Aldedh, Pro_dh, Pro_dh-DNA_bdg

K13821

3NIFX

Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family

ACIAD1649

putP

SSS family, major sodium/proline symporter

COG0591

SSF

K11928

3NIZF

Sugar (and other) transporter

ACIAD1651

pcaT

dicarboxylic acid transport protein; alpha-ketoglutarate permease (MFS superfamily)

COG0477

Sugar_tr

K02625

3NJTJ

Belongs to the cysteine synthase cystathionine beta- synthase family

ACIAD1662

cysK

subunit of cysteine synthase A and O-acetylserine sulfhydrolase A, PLP-dependent enzyme

COG0031

PALP

K01738

3NJE4

Sugar (and other) transporter

ACIAD1681

mucK

cis,cis-muconate transport protein (MFS superfamily)

COG0477

MFS_1, Sugar_tr

K08196

3NJ07

Major Facilitator Superfamily

ACIAD1685

putative transport protein (MFS superfamily)

MFS_1

3NJE4

Sugar (and other) transporter

ACIAD1694

dcaK

transport protein in catabolism of dicarboxylic acids (MFS superfamily)

COG0477

MFS_1

K08196

3NJ19

Major Facilitator Superfamily

ACIAD1698

putative transport protein (MFS superfamily)

MFS_1

3NIYK

Involved in the third step of the chorismate pathway, which leads to the biosynthesis of aromatic amino acids. Catalyzes the cis-dehydration of 3-dehydroquinate (DHQ) and introduces the first double bond of the aromatic ring to yield 3- dehydroshikimate

ACIAD1713

quiB

catabolic 3-dehydroquinate dehydratase (3- dehydroquinase)

COG0710

DHquinase_I

K03785

3NKGC

Major Facilitator Superfamily

ACIAD1727

hcaK

transporter of hydroxycinnamates (MFS superfamily)

COG0477

MFS_1, Sugar_tr

K05819

3NIYA

Catalyzes a trans-dehydration via an enolate intermediate

ACIAD1738

aroQ

3-dehydroquinate dehydratase, type II

COG0757

DHquinase_II

K03786

3NJZA

Fumarase C C-terminus

ACIAD1744

aspA

aspartate ammonia-lyase (aspartase)

COG1027

FumaraseC_C, Lyase_1

K01744

3NMA0

Bacterial transferase hexapeptide (six repeats)

ACIAD1763

srpH

serine acetyltransferase

COG1045

Hexapep

K00640

3NKAD

Periplasmic binding protein domain

ACIAD1765

putative branched-chain amino acid transport protein (ABC superfamily, peri_bind)

COG0683

Peripla_BP_5

K11959

3NJE3

Belongs to the binding-protein-dependent transport system permease family

ACIAD1766

putative branched-chain amino acid permease protein (ABC superfamily, membrane)

COG0559

BPD_transp_2

K11960

3NK6B

Belongs to the binding-protein-dependent transport system permease family

ACIAD1767

putative branched-chain amino acid permease protein (ABC superfamily, membrane)

BPD_transp_2

ABC transporter

putative branched-chain amino acid transport protein (ABC superfamily, ATP_bind)

COG0410

ABC_tran

K11963

3NM8D

Methylene-tetrahydrofolate reductase C terminal

ACIAD1783

putative methylenetetrahydrofolate reductase

COG0685

MTHFR, MTHFR_C

K00297

3NMRY

Major Facilitator Superfamily

ACIAD1804

putative permease (MFS superfamily)

MFS_1

3NMHR

Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily

ACIAD1805

putative glyoxalase (dioxygenase domain)

Glyoxalase

3NM0W

Major Facilitator

ACIAD1815

putative benzoate transport protein (BenK-like)(MFS superfamily)

COG0477

MFS_1

K05548

3NIMG

Involved in the import of serine and threonine into the cell, with the concomitant import of sodium (symport system)

ACIAD1866

sstT

transporter, sodium-dicarboxylate symporter family

SDF

MFS_1 like family

putative metabolite transporter (MFS superfamily)

COG0477

MFS_1_like

K05820

3NNJE

The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein

ACIAD1876

gcvH

glycine cleavage complex protein H, carrier of aminomethyl moiety via covalently bound lipoyl cofactor

COG0509

GCV_H

K02437

3NIQP

Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)

ACIAD1878

aro

3-deoxy-D-arabinoheptulosonate-7-phosphate synthase (DAHP synthetase), tyrosine repressible

COG0722

DAHP_synth_1

K01626

3NJUW

EamA-like transporter family

ACIAD1896

putative permease (drug/metabolite transporter)

EamA

3NSZJ

EamA-like transporter family

ACIAD1924

putative integral membrane protein

EamA

3NJEJ

Belongs to the glutamate synthase family

ACIAD1934

putative glutamate synthase.

Glu_synthase

3NM7M

ABC transporter

ACIAD1937

braG

branched-chain amino acid transport protein (ABC superfamily, ATP_bind)

COG0410

ABC_tran

K01996

3NMUF

Periplasmic binding protein

ACIAD1938

conserved hypothetical protein; putative membrane protein

COG0683

Peripla_BP_6

K01999

3NK6B

Belongs to the binding-protein-dependent transport system permease family

ACIAD1939

braE

branched-chain amino acid transport protein (ABC superfamily, membrane)

COG0559

BPD_transp_2

K01998

3NJE3

Belongs to the binding-protein-dependent transport system permease family

ACIAD1940

putative branched-chain amino acid permease protein (ABC superfamily, membrane)

COG0559

BPD_transp_2

K01997

3NT1M

Branched-chain amino acid ATP-binding cassette transporter

ACIAD1941

braF

branched-chain amino acid transport protein (ABC superfamily, atp_bind)

COG0411

ABC_tran, BCA_ABC_TP_C

K01995

3NJYN

Major Facilitator Superfamily

ACIAD1971

smvA

methyl viologen resistance protein (MFS superfamily)

COG0477

MFS_1

K08167

3NT7G

LysE type translocator

ACIAD1981

putative transport protein

COG1280

LysE

K11250

3NJZD

Metallopeptidase family M24

ACIAD1987

map

methionine aminopeptidase

COG0024

Peptidase_M24

K01265

3NK3Z

FAD dependent oxidoreductase

ACIAD1998

dadA

D-amino acid dehydrogenase, small subunit

COG0665

DAO

K00285

3NINW

Domain of unknown function (DUF3458_C) ARM repeats

ACIAD2008

pepN

aminopeptidase N

COG0308

DUF3458, DUF3458_C, Peptidase_M1

K01256

3NNMG

5-carboxymethyl-2-hydroxymuconate isomerase

ACIAD2013

putative 5-carboxymethyl-2-hydroxymuconate delta isomerase

CHMI

AzlC protein

putative branched-chain amino acid transport protein (AzlC)

AzlC

3NIIB

Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system

ACIAD2028

aroC

chorismate synthase

Chorismate_synt

ABC transporter

gltL

glutamate/aspartate transport protein (ABC superfamily, atp_bind)

COG1126

ABC_tran

K10004

3NSMP

Binding-protein-dependent transport system inner membrane component

ACIAD2059

gltJ

glutamate/aspartate transport protein (ABC superfamily, membrane)

COG0765

BPD_transp_1

K10003

3NK0B

Bacterial periplasmic substrate-binding proteins

ACIAD2061

gltI

glutamate/aspartate transport protein (ABC superfamily, peri_bind)

COG0834

SBP_bac_3

K10001

3NJ97

Aminotransferase class I and II

ACIAD2080

dapC

succinyldiaminopimelate transaminase

COG0436

Aminotran_1_2

K14267

3NP6X

LysE type translocator

ACIAD2083

putative amino acid efflux protein, putative threonine efflux protein

LysE

3NJ6Z

Aminotransferase

ACIAD2087

AlaA

glutamate-pyruvate aminotransferase

Aminotran_1_2

Asparaginase

aspQ

glutaminase-asparaginase

COG0252

Asparaginase

K05597

3NJAM

Serine acetyltransferase, N-terminal

ACIAD2091

cysE

serine acetyltransferase

COG1045

Hexapep, SATase_N

K00640

3NK66

EamA-like transporter family

ACIAD2115

hypothetical protein

3NSY8

Sugar (and other) transporter

ACIAD2122

putative multidrug resistance protein (MFS superfamily) (BfnC)

MFS_1

3NJKU

LysE type translocator

ACIAD2144

putative threonine efflux protein

LysE

3NJF0

Domain of unknown function (DUF3488)

ACIAD2201

conserved hypothetical protein; putative membrane protein

COG1305

DUF3488, Transglut_core

K22452

3NN4K

Catalyzes the conversion of hemimercaptal, formed from methylglyoxal and glutathione, to S-lactoylglutathione

ACIAD2213

gloA

lactoylglutathione lyase

COG0346

Glyoxalase

K01759

3NKXC

Peptidase family M20/M25/M40

ACIAD2220

pepD

aminoacyl-histidine dipeptidase (peptidase D)

COG2195

M20_dimer, Peptidase_M20

K01270

3NK5W

Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3- phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate

ACIAD2222

bifunctional protein [Includes: putative prephenate or cyclohexadienyl dehydrogenase; 3-phosphoshikimate 1-carboxyvinyltransferase (5- enolpyruvylshikimate-3-phosphate synthase) (EPSP synthase) (EPSPS) (AroA)]

EPSP_synthase, PDH

chorismate mutase

pheA

bifuctional protein [Includes: chorismate mutase P; prephenate dehydratase ]

COG0077, COG1605

ACT, CM_2, PDT

K14170

3NJHX

Glycosyl transferase family, helical bundle domain

ACIAD2229

putative transferase

Glycos_trans_3N, Glycos_transf_3

3NJSY

Asp/Glu/Hydantoin racemase

ACIAD2248

hyu

hydantoin-racemase

Asp_Glu_race

K16841

3NJDM

Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism

ACIAD2255

glyA

serine hydroxymethyltransferase

COG0112

SHMT

K00600

3NK8T

Methionine aminopeptidase

ACIAD2271

map

methionine aminopeptidase

COG0024

Peptidase_M24

K01265

3NJYI

Sugar (and other) transporter

ACIAD2280

proP

glycine/betaine transporter (MFS superfamily)

COG0477

Osmo_CC, Sugar_tr

K03762

3NK2Z

Methylenetetrahydrofolate reductase

ACIAD2283

metF

5,10-methylenetetrahydrofolate reductase

COG0685

MTHFR

K00297

3NIQC

Catalyzes the formation of L-homocysteine from O- succinyl-L-homoserine (OSHS) and hydrogen sulfide

ACIAD2314

metZ

o-acylhomoserine sulfhydrylase

COG0626

Cys_Met_Meta_PP

K10764

3NIZR

Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)

ACIAD2330

aro

phospho-2-dehydro-3-deoxyheptonate aldolase

DAHP_synth_1

AzlC protein

conserved hypothetical protein; putative branched-chain amino acid permease (azaleucine resistance)

AzlC

3NKNC

Sugar (and other) transporter

ACIAD2385

putative permease (MFS superfamily)

COG2814

MFS_1, Sugar_tr

K19577

3NIXV

Transmembrane secretion effector

ACIAD2404

putative permease (MFS superfamily)

MFS_1

3NJ0G

Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids

ACIAD2434

alr

alanine racemase 1, biosynthetic

COG0787

Ala_racemase_C, Ala_racemase_N

K01775

3NJC3

Bacterial transglutaminase-like N-terminal region

ACIAD2436

conserved hypothetical protein; putative transglutaminase

Bact_transglu_N, Transglut_core

3NJCF

glutamine synthetase

ACIAD2458

glnA

glutamine synthetase

COG0174

Gln-synt_C, Gln-synt_N

K01915

3NIZ1

component II

ACIAD2461

trpG

bifunctional protein:[Includes: para-aminobenzoate synthase glutamine amidotransferase component II (ADC synthase); anthranilate synthase component II]

COG0512

GATase

K01658

3NIQH

Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)

ACIAD2462

trpD

anthranilate phosphoribosyltransferase

COG0547

Glycos_trans_3N, Glycos_transf_3

K00766

3NJGD

Belongs to the TrpC family

ACIAD2463

trpC

indole-3-glycerol phosphate synthase (IGPS)

COG0134

IGPS

K01609

3NKC9

Membrane dipeptidase (Peptidase family M19)

ACIAD2508

acdP

Zn-dependent dipeptidase

Peptidase_M19

3NISZ

COG2610 H gluconate symporter and related permeases

ACIAD2510

putative D-beta-hydroxybutyrate permease

GntP_permease

3NJIA

Allophanate hydrolase subunit 2

ACIAD2518

pxpC

putative L-5-oxoprolinase (ATP-dependent) subunit C

CT_A_B, CT_C_D

3NR46

Bacterial extracellular solute-binding protein

ACIAD2524

putative substrate binding protein (ABC superfamily, peri_bind)

COG0687

SBP_bac_6

K02055

3NJEJ

Belongs to the glutamate synthase family

ACIAD2525

mgsC

putative N-methyl glutamate synthase subunit C

Glu_synthase

K22083

3NMPF

Glutamine synthetase, catalytic domain

ACIAD2528

gmaS

putative gamma glutamylmethylamide synthetase

COG0174

Gln-synt_C

K01915

3NKD6

Major Facilitator Superfamily

ACIAD2531

putative sugar efflux transporter (MFS superfamily)

COG2814

MFS_1

K03445

3NIH1

Sugar (and other) transporter

ACIAD2535

putative transporter (MFS superfamily)

Sugar_tr

3NN7E

Sarcosine oxidase, gamma subunit family

ACIAD2549

mgdD

putative N-methyl glutamate dehydrogenase/oxidoreductase subunit D

COG4583

SoxG

K00305

3NM8N

Glycine cleavage T-protein C-terminal barrel domain

ACIAD2550

mgdC

putative N-methyl glutamate dehydrogenase/oxidoreductase subunit C

COG0446

Fer2_4, GCV_T, GCV_T_C, Pyr_redox_2

K00302

3NP1A

Sarcosine oxidase, delta subunit family

ACIAD2551

mgdB

putative N-methyl glutamate dehydrogenase/oxidoreductase subunit B

COG4311

SoxD

K00304

3NMHX

FAD dependent oxidoreductase

ACIAD2552

mgdA

putative N-methyl glutamate dehydrogenase/oxidoreductase subunit A

COG0665

DAO

K00303

3NJEE

haloacid dehalogenase-like hydrolase

ACIAD2559

conserved hypothetical protein; putative phosphoserine phosphatase

HAD

3NIWZ

Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate

ACIAD2560

proB

gamma-glutamyl kinase

COG0263

AA_kinase, PUA

K00931

3NKE8

DegT/DnrJ/EryC1/StrS aminotransferase family

ACIAD2574

aspC

aspartate aminotransferase A

COG0436

Aminotran_1_2

K00812

3NIK0

Branched-chain amino acid aminotransferase 4-amino-4-deoxychorismate lyase

ACIAD2590

pabC

4-amino-4-deoxychorismate lyase

COG0115

Aminotran_4

K02619

3NINN

Belongs to the transferase hexapeptide repeat family

ACIAD2599

dapD

2,3,4,5-tetrahydropyridine-2-carboxylate N-succinyltransferase

COG2171

Hexapep, Hexapep_2, THDPS_N_2

K00674

3NIHX

Uncharacterised MFS-type transporter YbfB

ACIAD2610

putative transport protein (MFS superfamily)

MFS_4

3NK0I

EamA-like transporter family

ACIAD2643

conserved hypothetical protein; putative membrane protein

EamA

3NKGT

Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine

ACIAD2647

serC

3-phosphoserine aminotransferase

COG1932

Aminotran_5

K00831

3NIIS

Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan

ACIAD2659

dapF

diaminopimelate epimerase

COG0253

DAP_epimerase

K01778

3NJND

Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine

ACIAD2660

lysA

diaminopimelate decarboxylase

COG0019

Orn_Arg_deC_N, Orn_DAP_Arg_deC

K01586

3NJUE

Amino acid permease

ACIAD2662

cycA

D-alanine/D-serine/glycine transport protein (APC family)

COG1113

AA_permease

K11737

3NIYW

Belongs to the Glu Leu Phe Val dehydrogenases family

ACIAD2680

gdh

glutamate dehydrogenase (NAD(P)+) oxidoreductase protein

COG0334

ELFV_dehydrog, ELFV_dehydrog_N

K00261

3NK22

LysE type translocator

ACIAD2743

putative amino acid efflux transmembrane protein

LysE

3NJJ3

EamA-like transporter family

ACIAD2746

conserved hypothetical protein; putative membrane protein

EamA

1SAEH

Protein of unknown function (DUF2569)

ACIAD2752

hypothetical protein; putative membrane protein

DUF2569

3NJ30

Acetyl-coenzyme A transporter 1

ACIAD2763

fbsO

putative transport protein (MFS superfamily)

MFS_1

3NK2X

Belongs to the Orn Lys Arg decarboxylase class-II family

ACIAD2768

fbsJ

putative ornithine decarboxylase

COG1982

Orn_Arg_deC_N, Orn_DAP_Arg_deC

K01581

3NSNV

FAD dependent oxidoreductase

ACIAD2790

putative oxidoreductase

DAO

3NM36

HMGL-like

ACIAD2820

putative hydroxymethylglutaryl-CoA lyase

HMGL-like

Amino acid permease

putative amino acid transport protein (APC family)

AA_permease

3NJ30

Acetyl-coenzyme A transporter 1

ACIAD2963

putative transporter (MFS superfamily)

Acatn

3NJKE

Amino acid permease

ACIAD2969

aroP

aromatic amino acid transporter (APC family)

COG0833, COG1113

AA_permease

K03293

3NM4B

LysE type translocator

ACIAD2980

conserved hypothetical protein; putative amino acid efflux transmembrane protein

LysE

3NNHY

Glyoxalase-like domain

ACIAD2992

conserved hypothetical protein

3NIYY

Sugar (and other) transporter

ACIAD2997

putative transport protein (MFS superfamily)

Sugar_tr

3NJW4

Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline

ACIAD3032

proC

pyrroline-5-carboxylate reductase

COG0345

F420_oxidored, P5CR_dimer

K00286

3NJMG

Transmembrane secretion effector

ACIAD3048

putative transporter

MFS_3

3NJVZ

Belongs to the cysteine synthase cystathionine beta- synthase family

ACIAD3071

cysM

cysteine synthase B (O-acetylserine sulfhydrolase B)

COG0031

PALP

K12339

3NKS2

EamA-like transporter family

ACIAD3081

putative membrane protein

EamA

3NJ19

Major Facilitator Superfamily

ACIAD3084

putative transport protein (MFS superfamily)

MFS_1

3NK7Y

Acetolactate synthase small

ACIAD3103

ilvH

acetolactate synthase isozyme III, small subunit

COG0440

ACT_5, ALS_ss_C

K01653

3NJ7R

Belongs to the UPF0758 family

ACIAD3126

radC

DNA repair protein, associated with replication forks

COG2003

RadC

K03630

3NP9X

Protein of unknown function (DUF2789)

ACIAD3153

conserved hypothetical protein

DUF2789

3NTET

LysE type translocator

ACIAD3166

putative amino-acid efflux transmembrane protein

LysE

3NJDF

Sugar (and other) transporter

ACIAD3170

putative transporter (MFS superfamily)

MFS_1

Peptidase family M3

prlC

oligopeptidase A

COG0339

Peptidase_M3

K01414

3NJ2T

Cys/Met metabolism PLP-dependent enzyme

ACIAD3222

putative cystathionine beta-lyase, PLP-dependent (beta-cystathionase) (MetC)

COG0626

Cys_Met_Meta_PP

K01760

3NMU0

EamA-like transporter family

ACIAD3273

putative transporter

EamA

3NJNY

Sugar (and other) transporter

ACIAD3292

mdfA

multidrug/chloramphenicol efflux transport protein (MFS superfamily)

COG0477

MFS_1

K08160

3NINV

Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family

ACIAD3302

serA

D-3-phosphoglycerate dehydrogenase

COG0111

2-Hacid_dh, 2-Hacid_dh_C

K00058

3NPB3

Orn/Lys/Arg decarboxylase, C-terminal domain

ACIAD3341

putative arginine/lysine/ornithine decarboxylase

OKR_DC_1, OKR_DC_1_C

glutamate synthase

gltD

glutamate synthase small chain

COG0493

Fer4_20, Pyr_redox_2

K00266

3NJ2V

Glutamate synthase central domain

ACIAD3350

gltB

glutamate synthase large chain precursor

COG0067, COG0069, COG0070

GATase_2, GXGXG, Glu_syn_central, Glu_synthase

K00265

3NKDH

Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)

ACIAD3353

aroB

3-dehydroquinate synthase

COG0337

DHQ_synthase

K01735

3NK4W

Cys/Met metabolism PLP-dependent enzyme

ACIAD3382

metY

homocysteine synthase

COG2873

Cys_Met_Meta_PP

K01740

3NK7V

imidazoleglycerol-phosphate dehydratase

ACIAD3395

hisB

imidazoleglycerol-phosphate dehydratase

COG0131

IGPD

K01693

3NITT

IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR

ACIAD3396

hisH

imidazole glycerol phosphate synthetase, glutamine amidotransferase subunit

COG0118

GATase

K02501

3NK1S

1-(5-phosphoribosyl)-5- (5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase

ACIAD3398

hisA

phosphoribosylformimino-5-aminoimidazole carboxamide isomerase

COG0106

His_biosynth

K01814

3NIUS

IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit

ACIAD3404

hisF

imidazole glycerol phosphate synthase, cyclase subunit

COG0107

His_biosynth

K02500

1RR40

IrrE N-terminal-like domain

ACIAD3429

putative peptidase_M78 domain-containing protein

Peptidase_M78

3NJXN

Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family

ACIAD3446

gabT

4-aminobutyrate aminotransferase, PLP-dependent

Aminotran_3

Amino acid permease

gabP

gamma-aminobutyrate permease

COG1113

AA_permease

K11735

3NJ46

Sugar (and other) transporter

ACIAD3450

putative transport protein (MFS superfamily)

MFS_1

3NJH2

Bacterial periplasmic substrate-binding proteins

ACIAD3484

putative arginine/ornithine binding protein (ABC superfamily, peri_bind)(artI, aotJ)

COG0834

SBP_bac_3

K02030

3NM72

Belongs to the bacterial solute-binding protein 3 family

ACIAD3487

putative amino acid binding protein (ABC superfamily, peri_bind)

COG0834

SBP_bac_3

K02030

3NM70

Belongs to the peptidase M20A family. ArgE subfamily

ACIAD3489

argE

N-acetylornithine deacetylase

COG0624

M20_dimer, Peptidase_M20

K01438

3NITP

Cobalamin-independent synthase, Catalytic domain

ACIAD3523

metE

5-methyltetrahydropteroyltriglutamate- homocysteine methyltransferase

COG0620

Meth_synt_2

K00549

3NJU6

Cys/Met metabolism PLP-dependent enzyme

ACIAD3553

putative methionine aminotransferase, PLP-dependent

COG0436

Aminotran_1_2

K14287

3NJTN

phosphoserine phosphatase

ACIAD3567

serB

phosphoserine phosphatase

COG0560

ACT_6, HAD

K01079

3NKC2

Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily

ACIAD3579

fragment of putative homogentisate 1,2-dioxygenase

Glyoxalase

3NK9V

Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)

ACIAD3585

dapA

4-hydroxy-tetrahydrodipicolinate synthase

COG0329

DHDPS

K01714

3NMNW

Belongs to the bacterial solute-binding protein 3 family

ACIAD3588

putative amino acid-binding protein (ABC superfamily, peri_bind)

COG0834

SBP_bac_3

K02030

3NTMY

ATPases associated with a variety of cellular activities

ACIAD3592

putative amino acid transport protein (ABC superfamily, ATP_bind)

COG1126

ABC_tran

K02028

COG0346

lactoylglutathione lyase activity

ACIAD3609

hypothetical protein

COG0346

lactoylglutathione lyase activity

ACIAD3609

hypothetical protein

3NIRP

Major Facilitator Superfamily

ACIAD3617

putative transport protein (MFS superfamily)

COG2814

MFS_1

K19577

3NIYU

Catalyzes the conversion of 4-hydroxy- tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate

ACIAD3619

dapB

4-hydroxy-tetrahydrodipicolinate reductase

COG0289

DapB_C, DapB_N

K00215

3NJMA

Belongs to the IlvD Edd family

ACIAD3636

putative dihydroxyacid dehydratase (ilvD-like)

COG0129

ILVD_EDD

K01687

3NIHI

Major Facilitator Superfamily

ACIAD3678

putative multidrug resistence transporter (MFS superfamily)

COG0477

MFS_1

K03446

CDSs classified by EGGNOG in COG category E