Comparative Genomics

Label	Gene	Product	EC number	MCC rank	MCC	Distance rank	Distance	Rank	Correlation score
ACIAD3596		putative ATPase		1	1.000	358	0.973	2	0.852
ACIAD3558	phoR	two-component sensor	2.7.3.-	2	0.929	358	0.973	3	0.792
ACIAD3068	relA	GTP pyrophosphokinase (ATP:GTP 3'-pyrophosphotransferase) (ppGpp synthetase I) ((p)ppGpp synthetase)	2.7.6.5	3	0.902	358	0.973	4	0.768
ACIAD2448	purD	phosphoribosylamine--glycine ligase (GARS) (Glycinamide ribonucleotide synthetase) (Phosphoribosylglycinamide synthetase)	6.3.4.13	5	0.842	358	0.973	5	0.718
ACIAD2634	purM	phosphoribosylaminoimidazole synthetase	6.3.3.1	6	0.836	358	0.973	6	0.712
ACIAD0354	recN	DNA repair protein RecN		4	0.890	1052	0.940	7	0.709
ACIAD2312	recR	recombination protein, gap repair		10	0.821	358	0.973	8	0.700
ACIAD2896		conserved hypothetical protein		9	0.822	733	0.972	9	0.698
ACIAD3069	rumA	23S rRNA (Uracil-5-)-methyltransferase(23S rRNA(M- 5-U1939)-methyltransferase)	2.1.1.-	11	0.815	358	0.973	10	0.694
ACIAD3059		conserved hypothetical protein		12	0.813	358	0.973	11	0.692
ACIAD2893	coaD	phosphopantetheine adenylyltransferase	2.7.7.3	8	0.833	825	0.960	12	0.690
ACIAD3364	murF	UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase (UDP-MurNAc-pentapeptide synthetase) (D-alanyl-D- alanine-adding enzyme)	6.3.2.10	13	0.809	358	0.973	13	0.689
ACIAD0246	nrdR	Transcriptional repressor nrdR		14	0.808	358	0.973	14	0.688
ACIAD0266	xerD	site-specific tyrosine recombinase		15	0.805	358	0.973	15	0.686
ACIAD0050	rph	ribonuclease PH (RNase PH), tRNA nucleotidyltransferase	2.7.7.56	16	0.803	358	0.973	16	0.684
ACIAD0007		putative transport protein (ABC superfamily, atp_bind)		17	0.802	358	0.973	17	0.683
ACIAD2839	groES	chaperone Hsp10, affects cell division		20	0.791	358	0.973	18	0.674
ACIAD0270	murD	UDP-N-acetylmuramoylalanine-D-glutamate ligase	6.3.2.9	22	0.791	358	0.973	19	0.674
ACIAD2037	metK	methionine adenosyltransferase	2.5.1.6	23	0.787	358	0.973	20	0.671
ACIAD0306	rplL	50S ribosomal protein L7/L12		24	0.785	358	0.973	21	0.669
ACIAD3041	pheT	phenylalanyl-tRNA synthetase, beta subunit	6.1.1.20	26	0.782	358	0.973	22	0.667
ACIAD3201	rpmD	50S ribosomal protein L30		25	0.783	358	0.973	23	0.667
ACIAD3032	proC	pyrroline-5-carboxylate reductase	1.5.1.2	27	0.777	358	0.973	24	0.662
ACIAD0283	argH	argininosuccinate lyase (Arginosuccinase) (ASAL)	4.3.2.1	60	0.736	1	1.000	25	0.662
ACIAD3220	rpsJ	30S ribosomal protein S10		28	0.776	358	0.973	26	0.662
ACIAD0913	YggS	Pyridoxal phosphate homeostasis protein		29	0.776	358	0.973	27	0.661
ACIAD0596	glnE	glutamine synthetase adenylyltransferase	2.7.7.42	31	0.773	358	0.973	28	0.659
ACIAD3203	rplR	50S ribosomal protein L18		30	0.774	358	0.973	29	0.659
ACIAD3159	phoL	phosphate starvation-inducible protein (PhoH-like)		7	0.836	1297	0.935	30	0.657
ACIAD3062	folK	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase (7,8-dihydro-6-hydroxymethylpterin-pyrophosphokinase) (HPPK) (6-hydroxymethyl-7,8-dihydropterin pyrophosphokinase) (PPPK)	2.7.6.3	65	0.729	1	1.000	31	0.656
ACIAD0935		putative RNA polymerase sigma factor		19	0.792	825	0.960	32	0.656
ACIAD2560	proB	gamma-glutamyl kinase	2.7.2.11	34	0.768	358	0.973	33	0.655
ACIAD3366	ftsI	septum formation, penicillin binding protein 3, peptidoglycan synthetase	2.4.1.129	32	0.769	358	0.973	34	0.655
ACIAD3515	ddlB	D-alanine-D-alanine ligase B	6.3.2.4	33	0.769	358	0.973	35	0.655
ACIAD1262	vfr	cyclic AMP receptor protein		35	0.768	358	0.973	36	0.654
ACIAD0910	fur	negative regulator of ferric iron uptake		37	0.766	358	0.973	37	0.653
ACIAD1258	purA	adenylosuccinate synthetase	6.3.4.4	38	0.765	358	0.973	38	0.652
ACIAD1373	frr	ribosome releasing factor		40	0.761	358	0.973	39	0.649
ACIAD0526		putative protein controls HAP (6-N-hydroxylaminopurine) mutagenesis (Ham1)		75	0.722	1	1.000	40	0.649
ACIAD3207	rplE	50S ribosomal protein L5		41	0.758	358	0.973	41	0.646
ACIAD0135		putative transcriptional repressor (GalR/LacI family)		42	0.757	358	0.973	42	0.645
ACIAD3205	rpsH	30S ribosomal protein S8		43	0.753	358	0.973	43	0.642
ACIAD2350		putative deaminase		44	0.752	358	0.973	44	0.641
ACIAD3005	hflX	GTP-binding protein		46	0.750	358	0.973	45	0.639
ACIAD2432	rplI	50S ribosomal protein L9		45	0.750	358	0.973	46	0.639
ACIAD0260	gacA	response regulator (Global antibiotic and cyanide control protein, LuxR/UhpA family)		47	0.750	358	0.973	47	0.639
ACIAD0301	nusG	transcription antitermination protein		48	0.749	358	0.973	48	0.638
ACIAD0002	dnaN	DNA polymerase III, beta chain	2.7.7.7	49	0.749	358	0.973	49	0.638
ACIAD3638	sun	16S rRNA m5C967 SAM-dependent methyltransferase		18	0.798	1052	0.940	50	0.635
ACIAD0357		putative tRNA/rRNA methyltransferase	2.1.1.-	50	0.743	358	0.973	51	0.633
ACIAD0305	rplJ	50S ribosomal protein L10		52	0.743	358	0.973	52	0.633
ACIAD0644	folC	bifunctional protein [Includes: folylpolyglutamate synthase (FPGS); dihydrofolate synthase ].	6.3.2.17, 6.3.2.12	53	0.742	358	0.973	53	0.632
ACIAD2374	miaA	delta(2)-isopentenylpyrophosphate tRNA-adenosine transferase	2.5.1.75	55	0.740	358	0.973	54	0.630
ACIAD1376	dxr	1-deoxy-d-xylulose 5-phosphate reductoisomerase	1.1.1.267	21	0.791	1052	0.940	55	0.630
ACIAD0359	coaE	dephosphocoenzyme A kinase	2.7.1.24	56	0.740	358	0.973	56	0.630
ACIAD3219	rplC	50S ribosomal protein L3		57	0.739	358	0.973	57	0.630
ACIAD2550	mgdC	putative N-methyl glutamate dehydrogenase/oxidoreductase subunit C	1.5.3.1	99	0.699	1	1.000	58	0.629
ACIAD1605	mmsB	3-hydroxyisobutyrate dehydrogenase	1.1.1.31	97	0.699	1	1.000	59	0.629
ACIAD1317	gpsA	glycerol-3-phosphate dehydrogenase, biosynthetic	1.1.1.94	58	0.737	358	0.973	60	0.628
ACIAD3030	polA	DNA polymerase I, 3' --> 5' polymerase, 5' --> 3' and 3'--> 5' exonuclease	2.7.7.7	59	0.736	358	0.973	61	0.627
ACIAD0023	ribF	bifunctional protein [Includes: riboflavin kinase (Flavokinase); FMN adenylyltransferase (FAD pyrophosphorylase) (FAD synthetase)]	2.7.1.26, 2.7.7.2	61	0.735	358	0.973	62	0.626
ACIAD3200	rplO	50S ribosomal protein L15		62	0.732	358	0.973	63	0.624
ACIAD3363	mraY	phospho-N-acetylmuramoyl-pentapeptide transferase	2.7.8.13	63	0.731	358	0.973	64	0.623
ACIAD0368	nusA	transcription termination/antitermination, L factor (N utilization substance protein A)		66	0.728	358	0.973	65	0.620
ACIAD0363	tpiA	triosephosphate isomerase	5.3.1.1	64	0.729	733	0.972	66	0.620
ACIAD3516	murC	UDP-N-acetylmuramate--alanine ligase	6.3.2.8	67	0.727	358	0.973	67	0.619
ACIAD2269	rpsB	30S ribosomal protein S2		68	0.725	358	0.973	68	0.618
ACIAD0547	proA	gamma-glutamyl phosphate reductase (GPR) (Glutamate-5- semialdehyde dehydrogenase) (Glutamyl-gamma-semialdehyde dehydrogenase) (GSA dehydrogenase)	1.2.1.41	69	0.725	358	0.973	69	0.618
ACIAD3517	murG	UDP-N-acetylglucosamine:N-acetylmuramyl-(pentapeptide) pyrophosphoryl-undecaprenol N-acetylglucosamine transferase	2.4.1.227	71	0.724	358	0.973	70	0.617
ACIAD0561	ispG	1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate synthase		51	0.743	825	0.960	71	0.616
ACIAD1130		putative methyltransferase		74	0.722	358	0.973	72	0.615
ACIAD0883	rpsG	30S ribosomal protein S7		79	0.720	358	0.973	73	0.613
ACIAD3508		putative peptidase		77	0.721	733	0.972	74	0.613
ACIAD0302	rplK	50S ribosomal protein L11		80	0.717	358	0.973	75	0.611
ACIAD3202	rpsE	30S ribosomal protein S5		83	0.714	358	0.973	76	0.609
ACIAD3046	rplT	50S ribosomal protein L20, also posttranslational autoregulator		84	0.713	733	0.972	77	0.607
ACIAD1265	clpB	ATP-dependent protease, Hsp 100, part of multi-chaperone system with DnaK, DnaJ, and GrpE		86	0.710	358	0.973	78	0.605
ACIAD0685	rpe	D-ribulose-5-phosphate 3-epimerase	5.1.3.1	85	0.710	358	0.973	79	0.605
ACIAD2894	smpB	ssrA-binding protein (Small protein B)		88	0.709	358	0.973	80	0.604
ACIAD3380		putative transport protein (ABC superfamily, atp_bind)		87	0.709	358	0.973	81	0.604
ACIAD0664	hisC	histidinol-phosphate aminotransferase	2.6.1.9	146	0.670	1	1.000	82	0.603
ACIAD0663	hisD	Histidinol dehydrogenase (HDH)	1.1.1.23	156	0.667	1	1.000	83	0.600
ACIAD3395	hisB	imidazoleglycerol-phosphate dehydratase	4.2.1.19	36	0.767	1370	0.931	84	0.599
ACIAD0609	aspS	aspartyl-tRNA synthetase	6.1.1.12, 6.1.1.23, 6.1.1.-	92	0.701	358	0.973	85	0.598
ACIAD3235	recG	ATP-dependent DNA helicase		76	0.721	825	0.960	86	0.598
ACIAD3633	ndh	NADH dehydrogenase II	1.6.99.3	165	0.664	1	1.000	87	0.597
ACIAD0891		putative cell division protein, required for chromosome partitioning (FstK)		94	0.700	358	0.973	88	0.596
ACIAD0370	rbfA	ribosome-binding factor A		96	0.699	358	0.973	89	0.596
ACIAD0304	rplA	50S ribosomal protein L1		98	0.699	358	0.973	90	0.596
ACIAD0830	cafA	ribonuclease G, endoribonuclease G (cytoplasmic axial filament protein )	3.1.4.-	95	0.700	733	0.972	91	0.595
ACIAD0533	tig	trigger factor, molecular chaperone involved in septum formation		100	0.698	358	0.973	92	0.595
ACIAD2447	purH	bifunctional protein [Includes: phosphoribosylaminoimidazolecarboxamide formyltransferase (AICAR transformylase); IMP cyclohydrolase (Inosinicase) (IMP synthetase) (ATIC)]	2.1.2.3, 3.5.4.10	81	0.716	825	0.960	93	0.593
ACIAD1927	pgk	phosphoglycerate kinase	2.7.2.3	103	0.696	358	0.973	94	0.593
ACIAD0300	secE	preprotein translocase IISP family, membrane subunit		101	0.697	733	0.972	95	0.593
ACIAD3060	panC	pantoate--beta-alanine ligase (Pantothenate synthetase) (Pantoate activating enzyme)	6.3.2.1	82	0.714	825	0.960	96	0.592
ACIAD2569	uvrB	excinuclease ABC subunit B (ATP-dependent DNA excision repair enzyme UvrAC)		105	0.694	358	0.973	97	0.592
ACIAD1876	gcvH	glycine cleavage complex protein H, carrier of aminomethyl moiety via covalently bound lipoyl cofactor		179	0.654	1	1.000	98	0.589
ACIAD0479	asd	aspartate-semialdehyde dehydrogenase, NAD(P)-binding	1.2.1.11	109	0.691	358	0.973	99	0.589
ACIAD3080	pntA-1	pyridine nucleotide transhydrogenase (proton pump), alpha subunit (part1)	1.6.1.2	39	0.762	1721	0.926	100	0.588
ACIAD1395	mfd	transcription-repair coupling protein		111	0.690	358	0.973	101	0.588
ACIAD0648	secA	preprotein translocase, secretion protein of IISP family		110	0.691	358	0.973	102	0.588
ACIAD0001	dnaA	Chromosomal replication initiator protein dnaA		112	0.690	358	0.973	103	0.588
ACIAD1105	adk	adenylate kinase	2.7.4.3	113	0.689	358	0.973	104	0.587
ACIAD1151	argG	argininosuccinate synthetase	6.3.4.5	189	0.651	1	1.000	105	0.586
ACIAD0180	atpB	membrane-bound ATP synthase, F0 sector, subunit a, important for FO assembly	7.1.2.2	116	0.688	358	0.973	106	0.586
ACIAD2664	radA	DNA repair protein		118	0.687	358	0.973	107	0.585
ACIAD0183	atpF	membrane-bound ATP synthase, F0 sector, subunit b	7.1.2.2	119	0.686	358	0.973	108	0.585
ACIAD3218	rplD	50S ribosomal protein L4, regulates expression of S10 operon		117	0.687	358	0.973	109	0.585
ACIAD2583	lepB	leader peptidase (signal peptidase I) , serine protease	3.4.21.89	125	0.682	358	0.973	110	0.581
ACIAD3199	secY	secretion protein		124	0.682	358	0.973	111	0.581
ACIAD2102	hrpA	ATP-dependent helicase	3.6.1.15	128	0.681	358	0.973	112	0.580
ACIAD3076		conserved hypothetical protein		133	0.679	358	0.973	113	0.579
ACIAD2284		putative ribosomal RNA small subunit methyltransferase E (rsmE)	2.1.1.-	131	0.680	358	0.973	114	0.579
ACIAD0021	lspA	prolipoprotein signal peptidase (Signal peptidase II.)	3.4.23.36	132	0.679	358	0.973	115	0.579
ACIAD1332	tsaD	tRNA N6-adenosine threonylcarbamoyltransferase	3.4.24.57	130	0.680	733	0.972	116	0.578
ACIAD3125	dfp	bifunctional protein [Includes: 4'-phosphopantothenoylcysteine decarboxylase; phosphopantothenoylcysteine synthetase, FMN-binding]	4.1.1.36, 6.3.2.5	102	0.697	825	0.960	117	0.577
ACIAD1670		putative prolyl-tRNA synthetases		135	0.678	358	0.973	118	0.577
ACIAD0557	rlmN	23S rRNA adenosine methyltransferase	2.1.1.-	70	0.725	1052	0.940	119	0.577
ACIAD3659	purE	phosphoribosylaminoimidazole carboxylase, mutase subunit	4.1.1.21	209	0.642	1	1.000	120	0.577
ACIAD3214	rplV	50S ribosomal protein L22		136	0.676	358	0.973	121	0.576
ACIAD3349	gltD	glutamate synthase small chain	1.4.1.13	104	0.695	825	0.960	122	0.576
ACIAD3502	glmM	phosphoglucosamine mutase	5.4.2.10	137	0.676	358	0.973	123	0.576
ACIAD3137		putative nucleotide binding protein		73	0.722	1052	0.940	124	0.575
ACIAD0188	atpC	membrane-bound ATP synthase , F1 sector, epsilon-subunit	7.1.2.2	72	0.722	1052	0.940	125	0.575
ACIAD0530	leuA	2-isopropylmalate synthase (Alpha-isopropylmalate synthase) (Alpha-IPM synthetase)	2.3.3.13	219	0.638	1	1.000	126	0.574
ACIAD1921	ppiB	peptidyl-prolyl cis-trans isomerase precursor (PPIase) (Rotamase)	5.2.1.8	54	0.741	1423	0.927	127	0.573
ACIAD0225	dinP	DNA polymerase IV, devoid of proofreading, damage-inducible protein P	2.7.7.7	140	0.673	358	0.973	128	0.573
ACIAD0068	ptk	tyrosine-protein kinase, autophosphorylates	2.7.10.2	143	0.672	358	0.973	129	0.573
ACIAD3257	murI	glutamate racemase	5.1.1.3	141	0.673	358	0.973	130	0.573
ACIAD2860	carA	carbamoyl-phosphate synthase, small chain	6.3.5.5	145	0.671	358	0.973	131	0.572
ACIAD2052		putative transcriptional regulator (YebC like)		144	0.671	358	0.973	132	0.572
ACIAD3587	purC	phosphoribosylaminoimidazole-succinocarboxamide synthase	6.3.2.6	147	0.670	358	0.973	133	0.571
ACIAD2561		putative GTP-binding protein (Obg)		148	0.669	358	0.973	134	0.570
ACIAD2365	msbA	lipid transport protein, flippase (ABC superfamily, membrane (N-terminal), atp_bind (C-terminal))		226	0.633	1	1.000	135	0.570
ACIAD0660	murA	UDP-N-acetylglucosamine 1-carboxyvinyltransferase (Enoylpyruvate transferase) (UDP-N-acetylglucosamine enolpyruvyl transferase) (EPT)	2.5.1.7	149	0.669	358	0.973	136	0.570
ACIAD0535	clpX	ATP-dependent Clp protease ATP-binding subunit		115	0.688	825	0.960	137	0.570
ACIAD1672	mtlD	mannitol-1-phosphate 5-dehydrogenase	1.1.1.17	151	0.668	358	0.973	138	0.569
ACIAD3196	rpsK	30S ribosomal protein S11		153	0.667	358	0.973	139	0.569
ACIAD3208	rplX	50S ribosomal protein L24		152	0.668	358	0.973	140	0.569
ACIAD3038	rho	transcription termination factor		154	0.667	358	0.973	141	0.568
ACIAD3310	rplS	50S ribosomal protein L19		160	0.665	358	0.973	142	0.567
ACIAD2071		putative GTP-binding protein		164	0.665	358	0.973	143	0.566
ACIAD0151	guaA	GMP synthetase (glutamine aminotransferase)	6.3.5.2, 6.3.5.2	163	0.665	358	0.973	144	0.566
ACIAD2933		putative tRNA/rRNA methyltransferase	2.1.1.34	168	0.663	358	0.973	145	0.565
ACIAD2368	gidB	glucose-inhibited division protein B (methyltransferase)	2.1.-.-	169	0.662	358	0.973	146	0.564
ACIAD1385	recA	DNA strand exchange and recombination protein with protease and nuclease activity.		170	0.661	358	0.973	147	0.564
ACIAD0463	leuC	3-isopropylmalate dehydratase (isomerase), subunit with LeuD	4.2.1.33	78	0.721	1370	0.931	148	0.563
ACIAD1318		putative phosphohistidine phosphatase	3.1.3.-	251	0.624	1	1.000	149	0.562
ACIAD3216	rplB	50S ribosomal protein L2		171	0.659	358	0.973	150	0.562
ACIAD3324	gmk	guanylate kinase	2.7.4.8	172	0.659	358	0.973	151	0.562
ACIAD1062	ppk	polyphosphate kinase	2.7.4.1	173	0.658	358	0.973	152	0.561
ACIAD3204	rplF	50S ribosomal protein L6		175	0.657	358	0.973	153	0.560
ACIAD2584	lepA	GTP-binding protein		174	0.657	733	0.972	154	0.559
ACIAD0271	ftsW	cell division protein, stabililzes FtsZ ring		91	0.702	1052	0.940	155	0.559
ACIAD2635	purN	phosphoribosylglycinamide formyltransferase 1	2.1.2.2	139	0.673	825	0.960	156	0.558
ACIAD2557	dusB	tRNA-dihydrouridine synthase B	1.-.-.-	178	0.654	358	0.973	157	0.558
ACIAD1903	moaCB	bifunctional protein [Includes: molybdenum cofactor biosynthesis protein C; molybdenum cofactor biosynthesis protein B]		263	0.620	1	1.000	158	0.558
ACIAD0185	atpA	membrane-bound ATP synthase , F1 sector, alpha-subunit	7.1.2.2	180	0.654	358	0.973	159	0.557
ACIAD3313	rpsP	30S ribosomal protein S16		181	0.654	358	0.973	160	0.557
ACIAD3325	rpoZ	RNA polymerase, omega subunit	2.7.7.6	182	0.654	358	0.973	161	0.557
ACIAD1100		putative methyltransferase		186	0.652	358	0.973	162	0.556
ACIAD0565		putative GTP-binding protein EngA		188	0.651	358	0.973	163	0.555
ACIAD3238		putative hydrolase		274	0.616	1	1.000	164	0.554
ACIAD3572	nusB	transcription termination, L factor (N utilization substance protein B)		190	0.651	358	0.973	165	0.554
ACIAD3119		putative ribosome biogenesis GTPase RsgA		158	0.666	825	0.960	166	0.552
ACIAD2853	ftsH	cell division protein	3.4.24.-	193	0.650	733	0.972	167	0.552
ACIAD2348	cmk	cytidylate kinase (cytidine monophosphate (CMP) kinase)	2.7.4.25	157	0.666	825	0.960	168	0.552
ACIAD1405	iscR	repressor of the iscRSUA operon, involved in assembly of Fe-S clusters		106	0.694	1052	0.940	169	0.552
ACIAD3213	rpsC	30S ribosomal protein S3		196	0.647	358	0.973	170	0.551
ACIAD3575	glmU	bifunctional protein [Includes: UDP-N-acetylglucosamine pyrophosphorylase (N-acetylglucosamine-1-phosphate uridyltransferase); Glucosamine-1-phosphate N-acetyltransferase ]	2.7.7.23, 2.3.1.57	198	0.647	358	0.973	171	0.551
ACIAD1084	aceA	isocitrate lyase	4.1.3.1	283	0.611	1	1.000	172	0.550
ACIAD3209	rplN	50S ribosomal protein L14		201	0.646	358	0.973	173	0.550
ACIAD0209		putative Rossmann-fold nucleotide-binding protein involved in DNA uptake (Smf)		202	0.645	733	0.972	174	0.548
ACIAD3637	fmt	methionyl-tRNA formyltransferase	2.1.2.9	204	0.643	358	0.973	175	0.548
ACIAD2089	dnaE	DNA polymerase III, alpha chain	2.7.7.7	206	0.642	358	0.973	176	0.547
ACIAD2458	glnA	glutamine synthetase	6.3.1.2	211	0.641	358	0.973	177	0.546
ACIAD0677		putative glycoprotein endopeptidase metalloprotease	3.4.-.-	89	0.706	1423	0.927	178	0.546
ACIAD2580	era	GTP-binding protein,16S rRNA-binding,ribosome-associated GTPase		212	0.639	358	0.973	179	0.544
ACIAD1945	murB	UDP-N-acetylenolpyruvoylglucosamine reductase, FAD-binding	1.3.1.98	216	0.638	358	0.973	180	0.544
ACIAD1906	moaA	molybdopterin biosynthesis, protein A		298	0.604	1	1.000	181	0.544
ACIAD1357	ilvA	Threonine dehydratase biosynthetic (Threonine deaminase)	4.3.1.19	299	0.604	1	1.000	182	0.544
ACIAD0352	yqgF	holliday junction resolvase yqgF-like	3.1.-.-	214	0.639	358	0.973	183	0.544
ACIAD2852	folP	7,8-dihydropteroate synthase	2.5.1.15	122	0.683	1189	0.939	184	0.543
ACIAD3194	rpoA	RNA polymerase, alpha subunit	2.7.7.6	221	0.637	358	0.973	185	0.543
ACIAD1996	ispF	2C-methyl-D-erythritol 2,4-cyclodiphosphate synthase	4.6.1.12	126	0.681	1052	0.940	186	0.542
ACIAD1408	hupB	DNA-binding protein HU-beta		177	0.655	825	0.960	187	0.542
ACIAD3058	ptsO	phosphocarrier protein (HPr-like) NPr, nitrogen related, exchanges phosphate with Enzyme I		185	0.652	825	0.960	188	0.541
ACIAD2850	glxK	glycerate kinase	2.7.1.31	183	0.653	825	0.960	189	0.541
ACIAD2614	ruvA	holliday junction helicase subunit A		223	0.635	358	0.973	190	0.541
ACIAD1081		putative hemolysin-related protein		225	0.635	358	0.973	191	0.541
ACIAD0657	rpoN	RNA polymerase sigma-54 factor		93	0.701	1721	0.926	192	0.541
ACIAD1900	modB	molybdate transport protein (ABC superfamily, membrane)		129	0.681	1189	0.939	193	0.540
ACIAD2347	rpsA	30S ribosomal protein S1		229	0.633	358	0.973	194	0.539
ACIAD0279	phoU	transcriptional repressor for high affinity phosphate uptake		232	0.632	358	0.973	195	0.539
ACIAD3215	rpsS	30S ribosomal protein S19		228	0.633	358	0.973	196	0.539
ACIAD3247	dxs	1-deoxyxylulose-5-phosphate synthase	2.2.1.7	191	0.650	825	0.960	197	0.539
ACIAD0514	folA	dihydrofolate reductase	1.5.1.3	233	0.632	358	0.973	198	0.538
ACIAD2234	mrcB	bifunctional protein [Includes penicillin-insensitive transglycosylase; penicillin-sensitive transpeptidase] (penicillin-binding protein 1B)	2.4.1.129, 3.4.-.-	237	0.630	358	0.973	199	0.537
ACIAD1308	thiG	thiamine biosynthesis protein, thiazole moiety		237	0.630	358	0.973	200	0.537
ACIAD0703	typA	GTP-binding elongation factor family protein		243	0.627	358	0.973	201	0.535
ACIAD3350	gltB	glutamate synthase large chain precursor	1.4.1.13	107	0.693	1721	0.926	202	0.535
ACIAD2909	pth	peptidyl-tRNA hydrolase	3.1.1.29	248	0.626	358	0.973	203	0.534
ACIAD0930	glpK	glycerol kinase	2.7.1.30	318	0.594	1	1.000	204	0.534
ACIAD0182	atpE	membrane-bound ATP synthase, F0 sector, subunit c	7.1.2.2	246	0.627	358	0.973	205	0.534
ACIAD0472	infA	protein chain initiation factor IF-1		250	0.625	358	0.973	206	0.533
ACIAD2950	valS	valyl-tRNA synthetase	6.1.1.9	210	0.641	825	0.960	207	0.532
ACIAD0887	rimI	ribosomal-protein-alanine acetyltransferase (Acetylating enzyme for N-terminal of ribosomal protein S18)	2.3.1.267	325	0.589	1	1.000	208	0.531
ACIAD3455	uvrA	excinuclease ABC subunit A		254	0.624	358	0.973	209	0.531
ACIAD2566	rarD	chloramphenicol-sensitive protein		90	0.704	2233	0.915	210	0.530
ACIAD2411		molybdopterin biosynthesis protein (moeB) OR thiamin-thiazole moiety synthesis (thiF)		327	0.589	1	1.000	211	0.530
ACIAD1901	modA	molybdate transport protein (ABC superfamily, peri_bind)		155	0.667	1189	0.939	212	0.530
ACIAD2838	groEL	chaperone Hsp60, peptide-dependent ATPase, heat shock protein		217	0.638	825	0.960	213	0.529
ACIAD2400	copA	Copper-exporting P-type ATPase A		330	0.588	1	1.000	214	0.529
ACIAD0515	thyA	thymidylate synthase (TS) (TSase)	2.1.1.45	259	0.621	358	0.973	215	0.529
ACIAD0510	msrA	peptide methionine sulfoxide reductase (Protein- methionine-S-oxide reductase) (Peptide Met(O) reductase)	1.8.4.11	328	0.588	1	1.000	216	0.529
ACIAD2422		conserved hypothetical protein		162	0.665	1189	0.939	217	0.528
ACIAD1372	pyrH	uridylate kinase	2.7.4.-	262	0.620	358	0.973	218	0.528
ACIAD1266	ilvD	dihydroxy-acid dehydratase	4.2.1.9	123	0.682	1423	0.927	219	0.528
ACIAD0235	fadD	acyl-CoA synthetase (long-chain-fatty-acid--CoA ligase)	6.2.1.3	339	0.586	1	1.000	220	0.528
ACIAD3561	rhdA	thiosulfate sulfurtransferase (Rhodanese-like protein)	2.8.1.1	336	0.586	1	1.000	221	0.528
ACIAD3131		putative phosphoesterase (PHP family)		268	0.618	358	0.973	222	0.527
ACIAD3065		putative nucleoside triphosphate pyrophosphohydrolase (MazG)		222	0.636	825	0.960	223	0.527
ACIAD1999	ispD	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase	2.7.7.60	166	0.664	1189	0.939	224	0.527
ACIAD3197	rpsM	30S ribosomal protein S13		265	0.619	358	0.973	225	0.527
ACIAD2938	rpmA	50S ribosomal protein L27		271	0.618	358	0.973	226	0.526
ACIAD3353	aroB	3-dehydroquinate synthase	4.2.3.4	347	0.584	1	1.000	227	0.526
ACIAD3158		putative tRNA-i(6)A37 modification enzyme (MiaB)		227	0.633	825	0.960	228	0.525
ACIAD1135	nudC	NADH pyrophosphatase (NUDIX hydrolase family)	3.6.1.22	142	0.672	1370	0.931	229	0.525
ACIAD0187	atpD	membrane-bound ATP synthase , F1 sector, beta-subunit	7.1.2.2	273	0.616	358	0.973	230	0.525
ACIAD0364	secG	preprotein translocase IISP family, auxillary membrane component		276	0.615	358	0.973	231	0.524
ACIAD3300		putative FAD/FMN-containing dehydrogenase		354	0.582	1	1.000	232	0.524
ACIAD2008	pepN	aminopeptidase N	3.4.11.2	357	0.581	1	1.000	233	0.523
ACIAD1865		putative transcriptional regulator (ArsR family)		356	0.581	1	1.000	234	0.523
ACIAD3594		conserved hypothetical protein; putative diguanylate cyclase/phosphodiesterase		127	0.681	1921	0.924	235	0.523
ACIAD0661	hisG	ATP-phosphoribosyltransferase	2.4.2.17	361	0.580	1	1.000	236	0.522
ACIAD0245	amtB	ammonium transport protein (Amt family)		363	0.580	1	1.000	237	0.522
ACIAD3210	rpsQ	30S ribosomal protein S17		281	0.612	358	0.973	238	0.522
ACIAD3102	ilvC	acetohydroxy acid isomeroreductase and 2-dehydropantoate 2-reductase	1.1.1.86, 1.1.1.169	176	0.656	1189	0.939	239	0.521
ACIAD2213	gloA	lactoylglutathione lyase	4.4.1.5	364	0.579	1	1.000	240	0.521
ACIAD0407	hslO	heat shock protein Hsp33		138	0.673	1423	0.927	241	0.521
ACIAD3388	ompR	two-component response regulator		108	0.693	2233	0.915	242	0.521
ACIAD3064		putative DNA uptake protein and/or related DNA-binding protein		285	0.610	358	0.973	243	0.520
ACIAD2615	ruvB	holliday junction helicase, subunit B		184	0.653	1052	0.940	244	0.520
ACIAD2373	hfq	host factor I for bacteriophage Q beta replication, a growth-related protein		121	0.685	2199	0.917	245	0.518
ACIAD0469	leuB	3-isopropylmalate dehydrogenase	1.1.1.85	372	0.576	1	1.000	246	0.518
ACIAD2660	lysA	diaminopimelate decarboxylase	4.1.1.20	192	0.650	1052	0.940	247	0.517
ACIAD2613	dgt	deoxyguanosinetriphosphate triphosphohydrolase (dGTPase) (dGTP triphosphohydrolase)	3.1.5.1	378	0.575	1	1.000	248	0.517
ACIAD0898		putative outer membrane protein		252	0.624	825	0.960	249	0.517
ACIAD0838		conserved hypothetical protein; putative membrane protein		150	0.668	1423	0.927	250	0.517
ACIAD0402	pnp	polyribonucleotide nucleotidyltransferase (Polynucleotide phosphorylase) (PNPase)	2.7.7.8	293	0.607	358	0.973	251	0.517
ACIAD0186	atpG	membrane-bound ATP synthase , F1 sector, gamma-subunit	7.1.2.2	194	0.649	1052	0.940	252	0.517
ACIAD3036	ppx	exopolyphosphatase (ExopolyPase) (Metaphosphatase)	3.6.1.11	195	0.648	1052	0.940	253	0.516
ACIAD1253	alaS	alanyl-tRNA synthetase	6.1.1.7	257	0.623	825	0.960	254	0.516
ACIAD2934	cysG	multifunctional protein [Includes: Uroporphyrin-III C-methyltransferase (Urogen III methylase) (SUMT) (Uroporphyrinogen III methylase) (UROM); Precorrin-2 oxidase ; Ferrochelatase ] (Siroheme synthase)	2.1.1.107, 1.3.1.76, 4.99.1.4	385	0.573	1	1.000	255	0.515
ACIAD2612	purL	phosphoribosylformylglycinamidine synthase (FGAM synthase) (FGAMS) (Formylglycinamide ribotide amidotransferase) (FGARAT) (Formylglycinamide ribotide synthetase)	6.3.5.3	384	0.573	1	1.000	256	0.515
ACIAD3386		putative transcriptional accessory protein		120	0.686	2399	0.913	257	0.515
ACIAD2430	rpsF	30S ribosomal protein S6		296	0.605	733	0.972	258	0.514
ACIAD1389	rpsT	30S ribosomal protein S20		300	0.604	358	0.973	259	0.514
ACIAD0444		putative transcriptional regulator		161	0.665	1423	0.927	260	0.514
ACIAD0802		putative bicyclomycin/multidrug transport protein (MFS superfamily)		167	0.663	1423	0.927	261	0.513
ACIAD0342	pgsA	CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase (Phosphatidylglycerophosphate synthase) (PGP synthase)	2.7.8.5	305	0.602	358	0.973	262	0.513
ACIAD3306		conserved hypothetical protein; putative membrane protein		159	0.665	1721	0.926	263	0.513
ACIAD3365	murE	UDP-N-acetylmuramoylalanyl-D-glutamate-2, 6-diaminopimelate ligase	6.3.2.13	199	0.646	1189	0.939	264	0.513
ACIAD3503	guaB	IMP dehydrogenase	1.1.1.205	304	0.603	733	0.972	265	0.513
ACIAD1323	purF	amidophosphoribosyltransferase	2.4.2.14	400	0.567	1	1.000	266	0.510
ACIAD0833		putative 5'-adenylylsulfate reductase (APS reductase) (cysH-like)	1.8.99.2	399	0.567	1	1.000	267	0.510
ACIAD0632		putative glycerophosphodiester phosphodiesterase	3.1.4.46	404	0.566	1	1.000	268	0.510
ACIAD3599		putative transcriptional regulator; putative detoxification transcriptional regulator		208	0.642	1189	0.939	269	0.510
ACIAD1215	pstB	high-affinity phosphate transport protein (ABC superfamily, atp_bind)		311	0.596	358	0.973	270	0.508
ACIAD0284	algZ	alginate biosynthesis protein		215	0.638	1052	0.940	271	0.508
ACIAD3511	ftsZ	cell division protein,tubulin-like GTP-binding protein and GTPase, forms circumferential ring in cell division and participates in the septum formation		313	0.596	358	0.973	272	0.508
ACIAD3371	gltX	glutamyl-tRNA synthetase	6.1.1.17, 6.1.1.24	316	0.595	358	0.973	273	0.507
ACIAD1650	npdA	NAD-dependent deacetylase (Regulatory protein sirtuin family)	3.5.1.-	410	0.563	1	1.000	274	0.506
ACIAD3206	rpsN	30S ribosomal protein S14		317	0.594	358	0.973	275	0.506
ACIAD2897	rluD	ribosomal large subunit pseudouridine synthase D (Pseudouridylate synthase) (Uracil hydrolyase)	4.2.1.70	290	0.609	825	0.960	276	0.505
ACIAD2633		putative permease (PerM family)		287	0.610	825	0.960	277	0.505
ACIAD2376		putative ATPase with strong ADP affinity		323	0.592	358	0.973	278	0.504
ACIAD1916	fdhD	formate dehydrogenase formation protein	1.17.1.9	420	0.560	1	1.000	279	0.504
ACIAD1072	cysD	sulfate adenylyltransferase subunit 2 (Sulfate adenylate transferase) (SAT) (ATP-sulfurylase small subunit)	2.7.7.4	114	0.688	2714	0.902	280	0.504
ACIAD1059		putative ABC transporter permease		322	0.593	733	0.972	281	0.504
ACIAD0726	bfmR	response regulator in two-component regulatory system (bfmR/bfmS)		291	0.609	825	0.960	282	0.504
ACIAD2925	rpoD	sigma D (sigma 70) factor of RNA polymerase , major sigma factor during exponential growth		297	0.605	825	0.960	283	0.501
ACIAD2589		conserved hypothetical protein; putative periplasmic solute-binding protein		240	0.629	1052	0.940	284	0.501
ACIAD2061	gltI	glutamate/aspartate transport protein (ABC superfamily, peri_bind)		329	0.588	358	0.973	285	0.501
ACIAD0544	gntT	high-affinity gluconate permease (GntP family)		335	0.587	358	0.973	286	0.500
ACIAD0242		magnesium chelatase, competence related protein (ComM)		341	0.586	358	0.973	287	0.499
ACIAD3054	infC	protein chain initiation factor IF-3		346	0.585	358	0.973	288	0.498
ACIAD2433	dnaB	replicative DNA helicase;chromosome replication, chain elongation		343	0.585	358	0.973	289	0.498
ACIAD1314	rhlB	ATP-dependent RNA helicase (DEAD box)		218	0.638	1370	0.931	290	0.498
ACIAD1302	trmB	tRNA(guanine-7)methyltransferase	2.1.1.33	344	0.585	358	0.973	291	0.498
ACIAD0003	recF	DNA replication, recombinaison and repair protein		344	0.585	358	0.973	292	0.498
ACIAD2657	xerC	site-specific tyrosine recombinase		444	0.552	1	1.000	293	0.497
ACIAD0746		putative transcriptional regulator (LysR family)		205	0.643	1423	0.927	294	0.497
ACIAD0247	ribD	bifunctional protein [Includes: diaminohydroxyphosphoribosylaminopyrimidine deaminase (Riboflavin-specific deaminase); 5-amino-6-(5- phosphoribosylamino)uracil reductase (HTP reductase) ]	3.5.4.26, 1.1.1.193	207	0.642	1423	0.927	295	0.497
ACIAD1245	add	adenosine deaminase	3.5.4.4	235	0.630	1297	0.935	296	0.496
ACIAD0871	fabG	3-oxoacyl-[acyl-carrier-protein] reductase	1.1.1.100	449	0.551	1	1.000	297	0.496
ACIAD3212	rplP	50S ribosomal protein L16		360	0.581	358	0.973	298	0.495
ACIAD3619	dapB	4-hydroxy-tetrahydrodipicolinate reductase	1.17.1.8	253	0.624	1189	0.939	299	0.495
ACIAD1252	lysC	aspartate kinase	2.7.2.4	365	0.579	358	0.973	300	0.494
ACIAD0384	ubiE	S-adenosylmethionine : 2-DMK methyltransferase and 2-octaprenyl-6-methoxy-1,4-benzoquinone methylase	2.1.1.-	200	0.646	2005	0.921	301	0.494
ACIAD2463	trpC	indole-3-glycerol phosphate synthase (IGPS)	4.1.1.48	220	0.638	1423	0.927	302	0.493
ACIAD2429	cyoE	protoheme IX farnesyltransferase (heme O biosynthesis)	2.5.1.-	458	0.548	1	1.000	303	0.493
ACIAD0367		Putative ribosome maturation factor RimP		314	0.595	825	0.960	304	0.493
ACIAD3042	pheS	phenylalanyl-tRNA synthetase, alpha-subunit	6.1.1.20	267	0.618	1052	0.940	305	0.492
ACIAD3013	rpsI	30S ribosomal protein S9		367	0.578	358	0.973	306	0.492
ACIAD1902	moeA	molybdopterin biosynthesis protein		465	0.547	1	1.000	307	0.492
ACIAD0900	rep	ATP-dependent DNA helicase	3.6.1.-	368	0.578	358	0.973	308	0.492
ACIAD0466	leuD	3-isopropylmalate isomerase (dehydratase), subunit with LeuC	4.2.1.33	264	0.619	1189	0.939	309	0.492
ACIAD1637		antibiotic resistance protein (acepita)		369	0.577	733	0.972	310	0.491
ACIAD2427	cyoC	cytochrome o ubiquinol oxidase subunit III	1.10.3.-	203	0.643	2104	0.920	311	0.490
ACIAD2283	metF	5,10-methylenetetrahydrofolate reductase	1.5.1.20	376	0.575	358	0.973	312	0.490
ACIAD2079	glnD	uridylyltransferase	2.7.7.59	230	0.633	1423	0.927	313	0.489
ACIAD2018	acoD	Acetaldehyde dehydrogenase 2 (Acetaldehyde dehydrogenase II) (ACDH-II)	1.2.1.3	134	0.678	2819	0.896	314	0.489
ACIAD0636	trpB	tryptophan synthase beta chain	4.2.1.20	373	0.576	733	0.972	315	0.489
ACIAD0551	nagZ	beta-N-acetyl-D-glucosaminidase	3.2.1.52	324	0.591	825	0.960	316	0.489
ACIAD0004	gyrB	DNA gyrase, subunit B (type II topoisomerase)	5.6.2.2	379	0.573	358	0.973	317	0.489
ACIAD3236		putative DNA transformation protein (ComF)		277	0.614	1052	0.940	318	0.489
ACIAD3302	serA	D-3-phosphoglycerate dehydrogenase	1.1.1.95	480	0.543	1	1.000	319	0.489
ACIAD2581	rnc	ribonuclease III, ds RNA	3.1.26.3	380	0.573	358	0.973	320	0.488
ACIAD3396	hisH	imidazole glycerol phosphate synthetase, glutamine amidotransferase subunit	4.3.2.10	234	0.631	1423	0.927	321	0.488
ACIAD0881	rpsL	30S ribosomal protein S12		387	0.571	358	0.973	322	0.487
ACIAD0829		putative Maf-like protein		280	0.612	1052	0.940	323	0.487
ACIAD3169		putative transcriptional regulator (LysR family)		235	0.630	1721	0.926	324	0.486
ACIAD2659	dapF	diaminopimelate epimerase	5.1.1.7	242	0.628	1423	0.927	325	0.486
ACIAD1369	glnL	sensory kinase (soluble) in two-component regulatory system		197	0.647	2399	0.913	326	0.486
ACIAD0191		putative aldose 1-epimerase family protein		286	0.610	1052	0.940	327	0.486
ACIAD0114	dadR	transcriptional regulator for dadAX gene cluster (AsnC family)		489	0.540	1	1.000	328	0.486
ACIAD2973	kdpE	regulator of kdp operon (transcriptional effector)		224	0.635	2005	0.921	329	0.485
ACIAD2206	efp	elongation factor P		393	0.569	358	0.973	330	0.485
ACIAD1743		putative oxydoreductase protein, zinc-containing (quinone oxidoreductase, NADPH dependent)	1.6.5.-	239	0.630	1876	0.925	331	0.485
ACIAD0102	galE	UDP-glucose 4-epimerase (Galactowaldenase) (UDP-galactose 4-epimerase)	5.1.3.2	289	0.609	1052	0.940	332	0.485
ACIAD0107	lldR	transcriptional repressor for L-lactate utilization (GntR family)		244	0.627	1721	0.926	333	0.484
ACIAD0010		putative chaperone involved in Fe-S cluster assembly and activation (HesB-like)		249	0.626	1423	0.927	334	0.484
ACIAD3681	oxaA	Inner membrane protein (IMP) integration factor; binds TM regions of nascent IMPs; required for Sec-independent IMP integration; associated with the Sec translocase		391	0.570	733	0.972	335	0.484
ACIAD2290	cydA	cytochrome d terminal oxidase, polypeptide subunit I	1.10.3.-	245	0.627	1721	0.926	336	0.483
ACIAD1063	estR	esterase operon transcriptional regulator (LysR family)		401	0.567	358	0.973	337	0.483
ACIAD0863	scpA	chromosome condensation and partitioning factor		292	0.607	1052	0.940	338	0.483
ACIAD0474	truA	tRNA-pseudouridine synthase I	4.2.1.70	398	0.567	358	0.973	339	0.483
ACIAD3576	glmS	glucosamine--fructose-6-phosphate aminotransferase	2.6.1.16	397	0.567	358	0.973	340	0.483
ACIAD3160		putative metalloprotease ybeY-like	3.4.24.-	405	0.566	358	0.973	341	0.482
ACIAD0064		putative virulence factor MviN family (multidrug/oligosaccharidyl-lipid/polysaccharide exporter superfamily)		355	0.582	825	0.960	342	0.482
ACIAD3031		conserved hypothetical protein; putative integral membrane resistance protein		403	0.566	733	0.972	343	0.481
ACIAD2342		conserved hypothetical protein; putative transcriptional regulator		359	0.581	825	0.960	344	0.481
ACIAD1241		putative sulfate transporter		512	0.533	1	1.000	345	0.480
ACIAD1197		conserved hypothetical protein		507	0.533	1	1.000	346	0.480
ACIAD0276	thiC	hydroxymethylpyrimidine moiety synthesis in thiamin biosynthesis		302	0.603	1052	0.940	347	0.480
ACIAD0828	mreD	rod shape-determining protein		411	0.563	358	0.973	348	0.479
ACIAD3611	tag	3-methyl-adenine DNA glycosylase I, constitutive	3.2.2.20	260	0.621	1721	0.926	349	0.479
ACIAD3021		putative carbon-nitrogen hydrolase		269	0.618	1423	0.927	350	0.478
ACIAD2997		putative transport protein (MFS superfamily)		518	0.531	1	1.000	351	0.478
ACIAD1225	dacC	D-ala-D-ala-carboxypeptidase; penicillin-binding protein 5 (precursor)	3.4.16.4	272	0.618	1423	0.927	352	0.478
ACIAD0244	glnK	regulatory protein, P-II 2, for nitrogen assimilation by glutamine synthetase, regulates GlnL (NRII) and GlnE (ATase)		266	0.618	1423	0.927	353	0.478
ACIAD3658	purK	phosphoribosylaminoimidazole carboxylase ATPase subunit	4.1.1.21	515	0.531	1	1.000	354	0.478
ACIAD2899	dnaG	DNA primase	2.7.7.-	417	0.560	358	0.973	355	0.477
ACIAD2644		conserved hypothetical protein		213	0.639	2518	0.911	356	0.477
ACIAD0826	mreC	rod shape-determining protein		307	0.599	1052	0.940	357	0.477
ACIAD1778	fecI	alternative RNAP sigma factor required for fecA promoter recognition and ferric citrate transport; activated by FecR		419	0.560	733	0.972	358	0.476
ACIAD1604	mmsA	methylmalonate-semialdehyde dehydrogenase, oxidoreductase protein	1.2.1.27	231	0.632	2233	0.915	359	0.476
ACIAD0658		putative sigma(54) modulation protein RpoX		423	0.558	358	0.973	360	0.476
ACIAD0272		putative glutamyl t-RNA synthetase	6.1.1.17	309	0.598	1052	0.940	361	0.476
ACIAD3012	rplM	50S ribosomal protein L13		381	0.573	825	0.960	362	0.475
ACIAD1386	hslR	heat shock protein 15		278	0.614	1423	0.927	363	0.475
ACIAD1058		putative transport protein (ABC superfamily, atp_bind)		428	0.558	358	0.973	364	0.475
ACIAD3078	pntB	pyridine nucleotide transhydrogenase, beta subunit	1.6.1.2	275	0.615	1876	0.925	365	0.474
ACIAD2996		putative hemolysin III (HLY-III)		311	0.596	1052	0.940	366	0.474
ACIAD2903	ispE	4-diphosphocytidyl-2-C-methyl-D-erythritol kinase (CMK) (4-(cytidine-5'-diphospho)-2-C-methyl-D-erythritol kinase)	2.7.1.148	310	0.597	1189	0.939	367	0.474
ACIAD0013	tyrS	tyrosyl-tRNA synthetase	6.1.1.1	432	0.557	358	0.973	368	0.474
ACIAD2443	prmA	methylation of 50S ribosomal subunit protein L11 (ribosomal protein L11 methyltransferase)	2.1.1.-	389	0.571	825	0.960	369	0.473
ACIAD1983		putative transporter transmembrane protein (magnesium transporter)		319	0.594	1052	0.940	370	0.473
ACIAD3563	dtd	D-tyrosyl tRNA(tyr) deacylase	3.1.-.-	315	0.595	1189	0.939	371	0.472
ACIAD0687	pcoA	copper resistance protein A precursor		443	0.552	358	0.973	372	0.471
ACIAD2861	carB	carbamoyl-phosphate synthase, large subunit	6.3.5.5	448	0.551	358	0.973	373	0.470
ACIAD2587	nadB	L-aspartate oxidase (quinolinate synthetase B)	1.4.3.16	547	0.521	1	1.000	374	0.469
ACIAD0285	algR	alginate biosynthesis regulatory protein		326	0.589	1052	0.940	375	0.469
ACIAD3055	thrS	threonyl-tRNA synthetase	6.1.1.3	457	0.549	358	0.973	376	0.468
ACIAD1214	pstA	high-affinity phosphate transport protein (ABC superfamily, membrane)		454	0.549	358	0.973	377	0.468
ACIAD0076	rmlB	dTDP-D-glucose-4,6-dehydratase	4.2.1.46	456	0.549	358	0.973	378	0.468
ACIAD1362	clpS	substrate modulator for ClpAP, directs protease activity towards aggregated proteins		284	0.611	2005	0.921	379	0.467
ACIAD0642	trpA	tryptophan synthase alpha chain	4.2.1.20	301	0.604	1423	0.927	380	0.467
ACIAD0160		putative transcriptional regulator (AraC family)		333	0.587	1052	0.940	381	0.467
ACIAD3104	ilvI	acetolactate synthase III, large subunit	2.2.1.6	334	0.587	1189	0.939	382	0.466
ACIAD1930		conserved hypothetical protein; putative Maf-like protein		256	0.623	2518	0.911	383	0.466
ACIAD3354	aroK	shikimate-kinase	2.7.1.71	340	0.586	1052	0.940	384	0.466
ACIAD3526	crc	catabolite repression control protein		559	0.518	1	1.000	385	0.466
ACIAD2313		putative nucleoid-associated protein (YbaB like)		348	0.584	1052	0.940	386	0.465
ACIAD1908	nasA	nitrate reductase, large subunit	1.7.99.4	564	0.516	1	1.000	387	0.465
ACIAD0884	fusA	protein chain elongation factor EF-G, GTP-binding		469	0.545	358	0.973	388	0.465
ACIAD0707	mutM	formamidopyrimidine-DNA glycosylase	3.2.2.23	306	0.602	1423	0.927	389	0.465
ACIAD2275	lipA	lipoate synthase		261	0.620	2518	0.911	390	0.464
ACIAD2028	aroC	chorismate synthase	4.2.3.5	472	0.545	358	0.973	391	0.464
ACIAD2940	ispB	octaprenyl-diphosphate synthase (Octaprenyl pyrophosphate synthetase) (OPP synthetase)	2.5.1.-	575	0.514	1	1.000	392	0.463
ACIAD1674		conserved hypothetical protein; putative transporter		475	0.544	733	0.972	393	0.463
ACIAD1248	rnhB	RNAse HII	3.1.26.4	571	0.515	1	1.000	394	0.463
ACIAD1113	rlmH	Ribosomal RNA large subunit methyltransferase H	2.1.1.-	351	0.583	1189	0.939	395	0.463
ACIAD0429	norM	multidrug resistance protein (Na(+)/drug antiporter) (Multidrug- efflux transporter)		425	0.558	825	0.960	396	0.463
ACIAD3193	rplQ	50S ribosomal protein L17		482	0.543	358	0.973	397	0.463
ACIAD3217	rplW	50S ribosomal protein L23		572	0.515	1	1.000	398	0.463
ACIAD2832		putative transglycosylase		430	0.557	825	0.960	399	0.462
ACIAD2509	bdhA	3-hydroxybutyrate dehydrogenase	1.1.1.30	580	0.513	1	1.000	400	0.462
ACIAD1662	cysK	subunit of cysteine synthase A and O-acetylserine sulfhydrolase A, PLP-dependent enzyme	2.5.1.47	487	0.542	358	0.973	401	0.462
ACIAD0098		putative UDP-glucose lipid carrier transferase/glucose-1-phosphate transferase in colanic acid gene cluster (WcaJ)	2.7.-.-	427	0.558	825	0.960	402	0.462
ACIAD3528		conserved hypothetical protein; putative arsenate reductase and related		358	0.581	1189	0.939	403	0.462
ACIAD2361	holB	DNA polymerase III, delta prime subunit	2.7.7.7	303	0.603	2005	0.921	404	0.461
ACIAD1116	folN	5-formyltetrahydrofolate cyclo-ligase	6.3.3.2	587	0.512	1	1.000	405	0.461
ACIAD3246	suhB	inositol-1-monophosphatase (IMPase) (Inositol-1- phosphatase) (I-1-Pase)	3.1.3.25	431	0.557	825	0.960	406	0.461
ACIAD3103	ilvH	acetolactate synthase isozyme III, small subunit	2.2.1.6	362	0.580	1189	0.939	407	0.460
ACIAD3061	panB	3-methyl-2-oxobutanoate hydroxymethyltransferase (Ketopantoate hydroxymethyltransferase)	2.1.2.11	436	0.555	825	0.960	408	0.460
ACIAD2844	glpD	glycerol-3-phosphate dehydrogenase	1.1.5.3	255	0.623	2658	0.906	409	0.460
ACIAD1309	thiS	C-terminally thiocarboxylated form is intermediate sulfur donor in thiazole formation; part of ThiF/ThiS complex; complexes with ThiG also		493	0.540	358	0.973	410	0.460
ACIAD3088		putative tRNA threonylcarbamoyladenosine dehydratase (tcdA)		370	0.577	1052	0.940	411	0.459
ACIAD3023	ohr	organic hydroperoxide resistance protein		247	0.626	2714	0.902	412	0.459
ACIAD2474	hemE	uroporphyrinogen decarboxylase	4.1.1.37	288	0.609	2233	0.915	413	0.459
ACIAD2236		putative bifunctional protein [Includes: dGTP-pyrophosphohydrolase; thiamine phosphate synthase]		371	0.576	1052	0.940	414	0.459
ACIAD0868		conserved hypothetical protein		491	0.540	733	0.972	415	0.459
ACIAD0861		putative ribosomal large subunit pseudouridine synthase B (Pseudouridylate synthase) (Uracil hydrolyase)	4.2.1.70	495	0.539	358	0.973	416	0.459
ACIAD0691	sugE	suppressor of gro		320	0.593	1423	0.927	417	0.459
ACIAD3606	mutY	A/G specific adenine glycosylase	3.2.2.-	492	0.540	733	0.972	418	0.459
ACIAD3106	leuS	leucyl-tRNA synthetase	6.1.1.4	445	0.552	825	0.960	419	0.458
ACIAD1316		putative nitroreductase		279	0.613	2518	0.911	420	0.458
ACIAD0454	ptsP	phosphoenolpyruvate-protein phosphotransferase	2.7.3.9	353	0.583	1297	0.935	421	0.458
ACIAD3172		conserved hypothetical protein; putative fumarylacetoacetate hydrolase family protein		602	0.507	1	1.000	422	0.457
ACIAD1321	pyrD	dihydroorotate oxydase	1.3.98.1, 1.3.5.2	603	0.507	1	1.000	423	0.457
ACIAD0452		putative acyl-CoA dehydrogenase (AidB)	1.3.99.-	601	0.507	1	1.000	424	0.457
ACIAD0966		putative amino acid transport protein (LysE family)		241	0.629	2770	0.898	425	0.456
ACIAD0727	bfmS	sensory histidine kinase in two-component regulatory system (bfmR/bfmS)	2.7.13.3	503	0.535	358	0.973	426	0.456
ACIAD0504		putative transcriptional regulator (TetR-family)		452	0.550	825	0.960	427	0.456
ACIAD0231		conserved hypothetical protein		294	0.606	2233	0.915	428	0.456
ACIAD3398	hisA	phosphoribosylformimino-5-aminoimidazole carboxamide isomerase	5.3.1.16	349	0.584	1370	0.931	429	0.456
ACIAD1330		conserved hypothetical protein		453	0.550	825	0.960	430	0.455
ACIAD0286	hemC	porphobilinogen deaminase (PBG) (Hydroxymethylbilane synthase) (HMBS) (Pre-uroporphyrinogen synthase)	2.5.1.61	386	0.572	1189	0.939	431	0.455
ACIAD3231	tesB	acyl-CoA thioesterase II	3.1.2.-	270	0.618	2695	0.904	432	0.455
ACIAD3037	trxA	thioredoxin		390	0.570	1052	0.940	433	0.454
ACIAD2070	metI	D- and L-methionine transport protein (ABC superfamily, membrane)		510	0.533	358	0.973	434	0.454
ACIAD3195	rpsD	30S ribosomal protein S4		460	0.548	825	0.960	435	0.454
ACIAD3449	ssb	ssDNA-binding protein controls activity of RecBCD nuclease		508	0.533	358	0.973	436	0.454
ACIAD2654	etfA	electron transfer flavoprotein alpha-subunit		620	0.504	1	1.000	437	0.453
ACIAD2291	cydB	cytochrome d terminal oxidase polypeptide subunit II	1.10.3.-	332	0.587	1721	0.926	438	0.453
ACIAD1630	cfa	cyclopropane-fatty-acyl-phospholipid synthase	2.1.1.79	331	0.588	1721	0.926	439	0.453
ACIAD0629		conserved hypothetical protein		295	0.605	2454	0.912	440	0.453
ACIAD3368	mraW	Ribosomal RNA small subunit methyltransferase H	2.1.1.-	509	0.533	733	0.972	441	0.453
ACIAD0921		conserved hypothetical protein; putative nucleoside-diphosphate sugar epimerases (SulA family)		321	0.593	2104	0.920	442	0.452
ACIAD2001	eno	enolase	4.2.1.11	476	0.544	825	0.960	443	0.451
ACIAD1910	nasD	nitrite reductase, large subunit, nucleotide- and Fe/S-cluster binding	1.7.1.4	352	0.583	1423	0.927	444	0.451
ACIAD0502	rpmB	50S ribosomal protein L28		522	0.530	358	0.973	445	0.451
ACIAD3654	dnaK	chaperone Hsp70 in DNA biosynthesis/cell division		525	0.529	358	0.973	446	0.451
ACIAD0101	pgi	glucose-6-phosphate isomerase	5.3.1.9	530	0.528	358	0.973	447	0.450
ACIAD2994		putative acetyl transferase	2.3.1.-	388	0.571	1297	0.935	448	0.449
ACIAD2101		putative 3-oxoacyl-[acyl-carrier-protein] synthase III	2.3.1.41	486	0.542	825	0.960	449	0.449
ACIAD1047	pit	phosphate transporter		649	0.499	1	1.000	450	0.449
ACIAD0704	mscL	mechanosensitive channel		533	0.528	733	0.972	451	0.449
ACIAD0589		putative SecYEG protein translocase auxillary subunit (YajC)		532	0.528	733	0.972	452	0.449
ACIAD3404	hisF	imidazole glycerol phosphate synthase, cyclase subunit	4.1.3.-	650	0.499	1	1.000	453	0.449
ACIAD2908	rplY	50S ribosomal protein L25		536	0.526	358	0.973	454	0.448
ACIAD1057	tesA	multifunctional protein [Includes: acyl-CoA thioesterase I; protease I; lysophospholipaseL(I)]	3.1.2.-, 3.4.21.-, 3.1.1.5	392	0.569	1297	0.935	455	0.448
ACIAD3470	msuE	NADH-dependent FMN reductase	1.5.1.-	655	0.498	1	1.000	456	0.448
ACIAD1132		conserved hypothetical protein		538	0.525	358	0.973	457	0.447
ACIAD3311	trmD	tRNA (guanine-1-)-methyltransferase.	2.1.1.-	496	0.538	825	0.960	458	0.446
ACIAD3034	tilS	tRNA(Ile)-lysidine synthetase		545	0.523	358	0.973	459	0.445
ACIAD2939	rplU	50S ribosomal protein L21		543	0.523	358	0.973	460	0.445
ACIAD3514	ftsQ	cell division protein (in growth of wall at septum)		421	0.559	1052	0.940	461	0.445
ACIAD2647	serC	3-phosphoserine aminotransferase	2.6.1.52	394	0.569	1370	0.931	462	0.444
ACIAD2639	comA	competence factor involved in DNA uptake		548	0.521	358	0.973	463	0.444
ACIAD2596	cysA	sulfate permease A protein, chromate resistance (ABC superfamily, atp_bind)		671	0.493	1	1.000	464	0.444
ACIAD1904	moaE	molybdopterin converting factor, large subunit		666	0.494	1	1.000	465	0.444
ACIAD0404	crcB	high-copy crc-csp restores normal chromosome condensation in presence of camphor or mukB mutations		542	0.523	733	0.972	466	0.444
ACIAD0275	aspP	adenosine diphosphate sugar pyrophosphatase (ADP-ribose pyrophosphatase)	3.6.1.13	667	0.494	1	1.000	467	0.444
ACIAD0967	iciA	inhibitor of replication initiation (transcriptional regulator of dnaA and argK (affects arginine transport) (LysR family))		282	0.611	2770	0.898	468	0.443
ACIAD2876	sucA	2-oxoglutarate decarboxylase E1 component of the 2-oxoglutarate dehydrogenase complex	1.2.4.2	366	0.578	2005	0.921	469	0.442
ACIAD2099		putative hydrolases or acyltransferases (alpha/beta hydrolase superfamily)	3.1.-.-	679	0.491	1	1.000	470	0.442
ACIAD2255	glyA	serine hydroxymethyltransferase	2.1.2.1	514	0.532	825	0.960	471	0.441
ACIAD1377		putative membrane-associated Zn-dependent proteases 1		513	0.532	825	0.960	472	0.441
ACIAD0099	galU	UTP-glucose-1-phosphate uridylyltransferase	2.7.7.9	438	0.554	1052	0.940	473	0.441
ACIAD3322	ispH	4-hydroxy-3-methylbut-2-enyl diphosphate reductase (also involved in penicillin tolerance and control of the stringent response. Seems to directly or indirectly interact with relA to maintain it in an inactive form during normal growth.)	1.17.7.4	439	0.554	1052	0.940	474	0.441
ACIAD2091	cysE	serine acetyltransferase	2.3.1.30	440	0.553	1052	0.940	475	0.440
ACIAD0493	topA	DNA topoisomerase type I, omega protein	5.6.2.1	569	0.515	358	0.973	476	0.439
ACIAD3150		putative ribosomal RNA large subunit methyltransferase J		342	0.585	2454	0.912	477	0.438
ACIAD2418	prfA	peptide chain release factor 1		573	0.514	358	0.973	478	0.438
ACIAD0875	thiD	bifunctional protein [Includes: hydroxy-methylpyrimidine kinase (HMP kinase); hydroxy-phosphomethylpyrimidine kinase (HMP-P kinase)]	2.7.4.7	577	0.514	358	0.973	479	0.438
ACIAD3245		putative ATP-dependent RNA helicase		695	0.487	1	1.000	480	0.438
ACIAD3469		putative two-component response regulator		402	0.566	1423	0.927	481	0.438
ACIAD2518	pxpC	putative L-5-oxoprolinase (ATP-dependent) subunit C	3.5.2.9	534	0.528	825	0.960	482	0.437
ACIAD0039	argA	N-alpha-acetylglutamate synthase (amino-acid acetyltransferase)	2.3.1.1	407	0.565	1423	0.927	483	0.437
ACIAD3399		putative peptide synthetase		455	0.549	1052	0.940	484	0.437
ACIAD3447		putative transcriptional regulator (GntR family)		450	0.551	1189	0.939	485	0.437
ACIAD1045	metH	methionine synthase (B12-dependent homocysteine-N5-methyltetrahydrofolate transmethylase, repressor of metE and metF)	2.1.1.13	408	0.564	1423	0.927	486	0.436
ACIAD0839	ffh	4.5S-RNP protein, GTP binding export factor, part of signal recognition particle with 4.5 RNA		588	0.512	358	0.973	487	0.436
ACIAD0744	upp	uracil phosphoribosyltransferase	2.4.2.9	586	0.512	358	0.973	488	0.436
ACIAD2386	rih	ribonucleoside hydrolase	3.2.2.-	708	0.484	1	1.000	489	0.435
ACIAD1201	hemL	glutamate-1-semialdehyde aminotransferase	5.4.3.8	463	0.547	1189	0.939	490	0.435
ACIAD3389	envZ	sensory histidine kinase in two-component regulatory system with OmpR		539	0.524	825	0.960	491	0.435
ACIAD2392	rbsK	ribokinase	2.7.1.15	599	0.509	358	0.973	492	0.434
ACIAD2367	soj	chromosome partitioning protein		593	0.511	733	0.972	493	0.434
ACIAD2314	metZ	o-acylhomoserine sulfhydrylase	2.5.1.-	715	0.482	1	1.000	494	0.434
ACIAD1659		putative transcriptional regulator (LysR family); putative glycine cleavage system transcriptional activator (Gcv operon activator)(GcvA)		187	0.651	3154	0.861	495	0.434
ACIAD0380	hisIE	bifunctional protein [Includes: phosphoribosyl-AMP cyclohydrolase; phosphoribosyl-ATP pyrophosphatase]	3.5.4.19, 3.6.1.31	434	0.556	1370	0.931	496	0.434
ACIAD0297	trpE	anthranilate synthase component I	4.1.3.27	716	0.482	1	1.000	497	0.434
ACIAD3341		putative arginine/lysine/ornithine decarboxylase	4.1.1.-	416	0.562	1423	0.927	498	0.434
ACIAD3557	phoB	positive response regulator for the pho regulon, autophosphorylates and phosphorylates sensor PhoR		406	0.565	1921	0.924	499	0.434
ACIAD2408	folB	dihydroneopterin aldolase	4.1.2.25	474	0.544	1052	0.940	500	0.433
ACIAD1219	purB	adenylosuccinate lyase	4.3.2.2	600	0.508	358	0.973	501	0.433

ACIAD3596

putative ATPase

1

1.000

358

0.973

2

0.852

0

ACIAD3558

phoR

two-component sensor

2.7.3.-

2

0.929

358

0.973

3

0.792

0

ACIAD3068

relA

GTP pyrophosphokinase (ATP:GTP 3'-pyrophosphotransferase) (ppGpp synthetase I) ((p)ppGpp synthetase)

2.7.6.5

3

0.902

358

0.973

4

0.768

0

ACIAD2448

purD

phosphoribosylamine--glycine ligase (GARS) (Glycinamide ribonucleotide synthetase) (Phosphoribosylglycinamide synthetase)

6.3.4.13

5

0.842

358

0.973

5

0.718

0

ACIAD2634

purM

phosphoribosylaminoimidazole synthetase

6.3.3.1

6

0.836

358

0.973

6

0.712

0

ACIAD0354

recN

DNA repair protein RecN

4

0.890

1052

0.940

7

0.709

0

ACIAD2312

recR

recombination protein, gap repair

10

0.821

358

0.973

8

0.700

0

ACIAD2896

conserved hypothetical protein

9

0.822

733

0.972

9

0.698

0

ACIAD3069

rumA

23S rRNA (Uracil-5-)-methyltransferase(23S rRNA(M- 5-U1939)-methyltransferase)

2.1.1.-

11

0.815

358

0.973

10

0.694

0

ACIAD3059

conserved hypothetical protein

12

0.813

358

0.973

11

0.692

0

ACIAD2893

coaD

phosphopantetheine adenylyltransferase

2.7.7.3

8

0.833

825

0.960

12

0.690

0

ACIAD3364

murF

UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase (UDP-MurNAc-pentapeptide synthetase) (D-alanyl-D- alanine-adding enzyme)

6.3.2.10

13

0.809

358

0.973

13

0.689

0

ACIAD0246

nrdR

Transcriptional repressor nrdR

14

0.808

358

0.973

14

0.688

0

ACIAD0266

xerD

site-specific tyrosine recombinase

15

0.805

358

0.973

15

0.686

0

ACIAD0050

rph

ribonuclease PH (RNase PH), tRNA nucleotidyltransferase

2.7.7.56

16

0.803

358

0.973

16

0.684

0

ACIAD0007

putative transport protein (ABC superfamily, atp_bind)

17

0.802

358

0.973

17

0.683

0

ACIAD2839

groES

chaperone Hsp10, affects cell division

20

0.791

358

0.973

18

0.674

0

ACIAD0270

murD

UDP-N-acetylmuramoylalanine-D-glutamate ligase

6.3.2.9

22

0.791

358

0.973

19

0.674

0

ACIAD2037

metK

methionine adenosyltransferase

2.5.1.6

23

0.787

358

0.973

20

0.671

0

ACIAD0306

rplL

50S ribosomal protein L7/L12

24

0.785

358

0.973

21

0.669

0

ACIAD3041

pheT

phenylalanyl-tRNA synthetase, beta subunit

6.1.1.20

26

0.782

358

0.973

22

0.667

0

ACIAD3201

rpmD

50S ribosomal protein L30

25

0.783

358

0.973

23

0.667

0

ACIAD3032

proC

pyrroline-5-carboxylate reductase

1.5.1.2

27

0.777

358

0.973

24

0.662

0

ACIAD0283

argH

argininosuccinate lyase (Arginosuccinase) (ASAL)

4.3.2.1

60

0.736

1

1.000

25

0.662

0

ACIAD3220

rpsJ

30S ribosomal protein S10

28

0.776

358

0.973

26

0.662

0

ACIAD0913

YggS

Pyridoxal phosphate homeostasis protein

29

0.776

358

0.973

27

0.661

0

ACIAD0596

glnE

glutamine synthetase adenylyltransferase

2.7.7.42

31

0.773

358

0.973

28

0.659

0

ACIAD3203

rplR

50S ribosomal protein L18

30

0.774

358

0.973

29

0.659

0

ACIAD3159

phoL

phosphate starvation-inducible protein (PhoH-like)

7

0.836

1297

0.935

30

0.657

0

ACIAD3062

folK

2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase (7,8-dihydro-6-hydroxymethylpterin-pyrophosphokinase) (HPPK) (6-hydroxymethyl-7,8-dihydropterin pyrophosphokinase) (PPPK)

2.7.6.3

65

0.729

1

1.000

31

0.656

0

ACIAD0935

putative RNA polymerase sigma factor

19

0.792

825

0.960

32

0.656

0

ACIAD2560

proB

gamma-glutamyl kinase

2.7.2.11

34

0.768

358

0.973

33

0.655

0

ACIAD3366

ftsI

septum formation, penicillin binding protein 3, peptidoglycan synthetase

2.4.1.129

32

0.769

358

0.973

34

0.655

0

ACIAD3515

ddlB

D-alanine-D-alanine ligase B

6.3.2.4

33

0.769

358

0.973

35

0.655

0

ACIAD1262

vfr

cyclic AMP receptor protein

35

0.768

358

0.973

36

0.654

0

ACIAD0910

fur

negative regulator of ferric iron uptake

37

0.766

358

0.973

37

0.653

0

ACIAD1258

purA

adenylosuccinate synthetase

6.3.4.4

38

0.765

358

0.973

38

0.652

0

ACIAD1373

frr

ribosome releasing factor

40

0.761

358

0.973

39

0.649

0

ACIAD0526

putative protein controls HAP (6-N-hydroxylaminopurine) mutagenesis (Ham1)

75

0.722

1

1.000

40

0.649

0

ACIAD3207

rplE

50S ribosomal protein L5

41

0.758

358

0.973

41

0.646

0

ACIAD0135

putative transcriptional repressor (GalR/LacI family)

42

0.757

358

0.973

42

0.645

0

ACIAD3205

rpsH

30S ribosomal protein S8

43

0.753

358

0.973

43

0.642

0

ACIAD2350

putative deaminase

44

0.752

358

0.973

44

0.641

0

ACIAD3005

hflX

GTP-binding protein

46

0.750

358

0.973

45

0.639

0

ACIAD2432

rplI

50S ribosomal protein L9

45

0.750

358

0.973

46

0.639

0

ACIAD0260

gacA

response regulator (Global antibiotic and cyanide control protein, LuxR/UhpA family)

47

0.750

358

0.973

47

0.639

0

ACIAD0301

nusG

transcription antitermination protein

48

0.749

358

0.973

48

0.638

0

ACIAD0002

dnaN

DNA polymerase III, beta chain

2.7.7.7

49

0.749

358

0.973

49

0.638

0

ACIAD3638

sun

16S rRNA m5C967 SAM-dependent methyltransferase

18

0.798

1052

0.940

50

0.635

0

ACIAD0357

putative tRNA/rRNA methyltransferase

2.1.1.-

50

0.743

358

0.973

51

0.633

0

ACIAD0305

rplJ

50S ribosomal protein L10

52

0.743

358

0.973

52

0.633

0

ACIAD0644

folC

bifunctional protein [Includes: folylpolyglutamate synthase (FPGS); dihydrofolate synthase ].

6.3.2.17, 6.3.2.12

53

0.742

358

0.973

53

0.632

0

ACIAD2374

miaA

delta(2)-isopentenylpyrophosphate tRNA-adenosine transferase

2.5.1.75

55

0.740

358

0.973

54

0.630

0

ACIAD1376

dxr

1-deoxy-d-xylulose 5-phosphate reductoisomerase

1.1.1.267

21

0.791

1052

0.940

55

0.630

0

ACIAD0359

coaE

dephosphocoenzyme A kinase

2.7.1.24

56

0.740

358

0.973

56

0.630

0

ACIAD3219

rplC

50S ribosomal protein L3

57

0.739

358

0.973

57

0.630

0

ACIAD2550

mgdC

putative N-methyl glutamate dehydrogenase/oxidoreductase subunit C

1.5.3.1

99

0.699

1

1.000

58

0.629

0

ACIAD1605

mmsB

3-hydroxyisobutyrate dehydrogenase

1.1.1.31

97

0.699

1

1.000

59

0.629

0

ACIAD1317

gpsA

glycerol-3-phosphate dehydrogenase, biosynthetic

1.1.1.94

58

0.737

358

0.973

60

0.628

0

ACIAD3030

polA

DNA polymerase I, 3' --> 5' polymerase, 5' --> 3' and 3'--> 5' exonuclease

2.7.7.7

59

0.736

358

0.973

61

0.627

0

ACIAD0023

ribF

bifunctional protein [Includes: riboflavin kinase (Flavokinase); FMN adenylyltransferase (FAD pyrophosphorylase) (FAD synthetase)]

2.7.1.26, 2.7.7.2

61

0.735

358

0.973

62

0.626

0

ACIAD3200

rplO

50S ribosomal protein L15

62

0.732

358

0.973

63

0.624

0

ACIAD3363

mraY

phospho-N-acetylmuramoyl-pentapeptide transferase

2.7.8.13

63

0.731

358

0.973

64

0.623

0

ACIAD0368

nusA

transcription termination/antitermination, L factor (N utilization substance protein A)

66

0.728

358

0.973

65

0.620

0

ACIAD0363

tpiA

triosephosphate isomerase

5.3.1.1

64

0.729

733

0.972

66

0.620

0

ACIAD3516

murC

UDP-N-acetylmuramate--alanine ligase

6.3.2.8

67

0.727

358

0.973

67

0.619

0

ACIAD2269

rpsB

30S ribosomal protein S2

68

0.725

358

0.973

68

0.618

0

ACIAD0547

proA

gamma-glutamyl phosphate reductase (GPR) (Glutamate-5- semialdehyde dehydrogenase) (Glutamyl-gamma-semialdehyde dehydrogenase) (GSA dehydrogenase)

1.2.1.41

69

0.725

358

0.973

69

0.618

0

ACIAD3517

murG

UDP-N-acetylglucosamine:N-acetylmuramyl-(pentapeptide) pyrophosphoryl-undecaprenol N-acetylglucosamine transferase

2.4.1.227

71

0.724

358

0.973

70

0.617

0

ACIAD0561

ispG

1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate synthase

51

0.743

825

0.960

71

0.616

0

ACIAD1130

putative methyltransferase

74

0.722

358

0.973

72

0.615

0

ACIAD0883

rpsG

30S ribosomal protein S7

79

0.720

358

0.973

73

0.613

0

ACIAD3508

putative peptidase

77

0.721

733

0.972

74

0.613

0

ACIAD0302

rplK

50S ribosomal protein L11

80

0.717

358

0.973

75

0.611

0

ACIAD3202

rpsE

30S ribosomal protein S5

83

0.714

358

0.973

76

0.609

0

ACIAD3046

rplT

50S ribosomal protein L20, also posttranslational autoregulator

84

0.713

733

0.972

77

0.607

0

ACIAD1265

clpB

ATP-dependent protease, Hsp 100, part of multi-chaperone system with DnaK, DnaJ, and GrpE

86

0.710

358

0.973

78

0.605

0

ACIAD0685

rpe

D-ribulose-5-phosphate 3-epimerase

5.1.3.1

85

0.710

358

0.973

79

0.605

0

ACIAD2894

smpB

ssrA-binding protein (Small protein B)

88

0.709

358

0.973

80

0.604

0

ACIAD3380

putative transport protein (ABC superfamily, atp_bind)

87

0.709

358

0.973

81

0.604

0

ACIAD0664

hisC

histidinol-phosphate aminotransferase

2.6.1.9

146

0.670

1

1.000

82

0.603

0

ACIAD0663

hisD

Histidinol dehydrogenase (HDH)

1.1.1.23

156

0.667

1

1.000

83

0.600

0

ACIAD3395

hisB

imidazoleglycerol-phosphate dehydratase

4.2.1.19

36

0.767

1370

0.931

84

0.599

0

ACIAD0609

aspS

aspartyl-tRNA synthetase

6.1.1.12, 6.1.1.23, 6.1.1.-

92

0.701

358

0.973

85

0.598

0

ACIAD3235

recG

ATP-dependent DNA helicase

76

0.721

825

0.960

86

0.598

0

ACIAD3633

ndh

NADH dehydrogenase II

1.6.99.3

165

0.664

1

1.000

87

0.597

0

ACIAD0891

putative cell division protein, required for chromosome partitioning (FstK)

94

0.700

358

0.973

88

0.596

0

ACIAD0370

rbfA

ribosome-binding factor A

96

0.699

358

0.973

89

0.596

0

ACIAD0304

rplA

50S ribosomal protein L1

98

0.699

358

0.973

90

0.596

0

ACIAD0830

cafA

ribonuclease G, endoribonuclease G (cytoplasmic axial filament protein )

3.1.4.-

95

0.700

733

0.972

91

0.595

0

ACIAD0533

tig

trigger factor, molecular chaperone involved in septum formation

100

0.698

358

0.973

92

0.595

0

ACIAD2447

purH

bifunctional protein [Includes: phosphoribosylaminoimidazolecarboxamide formyltransferase (AICAR transformylase); IMP cyclohydrolase (Inosinicase) (IMP synthetase) (ATIC)]

2.1.2.3, 3.5.4.10

81

0.716

825

0.960

93

0.593

0

ACIAD1927

pgk

phosphoglycerate kinase

2.7.2.3

103

0.696

358

0.973

94

0.593

0

ACIAD0300

secE

preprotein translocase IISP family, membrane subunit

101

0.697

733

0.972

95

0.593

0

ACIAD3060

panC

pantoate--beta-alanine ligase (Pantothenate synthetase) (Pantoate activating enzyme)

6.3.2.1

82

0.714

825

0.960

96

0.592

0

ACIAD2569

uvrB

excinuclease ABC subunit B (ATP-dependent DNA excision repair enzyme UvrAC)

105

0.694

358

0.973

97

0.592

0

ACIAD1876

gcvH

glycine cleavage complex protein H, carrier of aminomethyl moiety via covalently bound lipoyl cofactor

179

0.654

1

1.000

98

0.589

0

ACIAD0479

asd

aspartate-semialdehyde dehydrogenase, NAD(P)-binding

1.2.1.11

109

0.691

358

0.973

99

0.589

0

ACIAD3080

pntA-1

pyridine nucleotide transhydrogenase (proton pump), alpha subunit (part1)

1.6.1.2

39

0.762

1721

0.926

100

0.588

0

ACIAD1395

mfd

transcription-repair coupling protein

111

0.690

358

0.973

101

0.588

0

ACIAD0648

secA

preprotein translocase, secretion protein of IISP family

110

0.691

358

0.973

102

0.588

0

ACIAD0001

dnaA

Chromosomal replication initiator protein dnaA

112

0.690

358

0.973

103

0.588

0

ACIAD1105

adk

adenylate kinase

2.7.4.3

113

0.689

358

0.973

104

0.587

0

ACIAD1151

argG

argininosuccinate synthetase

6.3.4.5

189

0.651

1

1.000

105

0.586

0

ACIAD0180

atpB

membrane-bound ATP synthase, F0 sector, subunit a, important for FO assembly

7.1.2.2

116

0.688

358

0.973

106

0.586

0

ACIAD2664

radA

DNA repair protein

118

0.687

358

0.973

107

0.585

0

ACIAD0183

atpF

membrane-bound ATP synthase, F0 sector, subunit b

7.1.2.2

119

0.686

358

0.973

108

0.585

0

ACIAD3218

rplD

50S ribosomal protein L4, regulates expression of S10 operon

117

0.687

358

0.973

109

0.585

0

ACIAD2583

lepB

leader peptidase (signal peptidase I) , serine protease

3.4.21.89

125

0.682

358

0.973

110

0.581

0

ACIAD3199

secY

secretion protein

124

0.682

358

0.973

111

0.581

0

ACIAD2102

hrpA

ATP-dependent helicase

3.6.1.15

128

0.681

358

0.973

112

0.580

0

ACIAD3076

conserved hypothetical protein

133

0.679

358

0.973

113

0.579

0

ACIAD2284

putative ribosomal RNA small subunit methyltransferase E (rsmE)

2.1.1.-

131

0.680

358

0.973

114

0.579

0

ACIAD0021

lspA

prolipoprotein signal peptidase (Signal peptidase II.)

3.4.23.36

132

0.679

358

0.973

115

0.579

0

ACIAD1332

tsaD

tRNA N6-adenosine threonylcarbamoyltransferase

3.4.24.57

130

0.680

733

0.972

116

0.578

0

ACIAD3125

dfp

bifunctional protein [Includes: 4'-phosphopantothenoylcysteine decarboxylase; phosphopantothenoylcysteine synthetase, FMN-binding]

4.1.1.36, 6.3.2.5

102

0.697

825

0.960

117

0.577

0

ACIAD1670

putative prolyl-tRNA synthetases

135

0.678

358

0.973

118

0.577

0

ACIAD0557

rlmN

23S rRNA adenosine methyltransferase

2.1.1.-

70

0.725

1052

0.940

119

0.577

0

ACIAD3659

purE

phosphoribosylaminoimidazole carboxylase, mutase subunit

4.1.1.21

209

0.642

1

1.000

120

0.577

0

ACIAD3214

rplV

50S ribosomal protein L22

136

0.676

358

0.973

121

0.576

0

ACIAD3349

gltD

glutamate synthase small chain

1.4.1.13

104

0.695

825

0.960

122

0.576

0

ACIAD3502

glmM

phosphoglucosamine mutase

5.4.2.10

137

0.676

358

0.973

123

0.576

0

ACIAD3137

putative nucleotide binding protein

73

0.722

1052

0.940

124

0.575

0

ACIAD0188

atpC

membrane-bound ATP synthase , F1 sector, epsilon-subunit

7.1.2.2

72

0.722

1052

0.940

125

0.575

0

ACIAD0530

leuA

2-isopropylmalate synthase (Alpha-isopropylmalate synthase) (Alpha-IPM synthetase)

2.3.3.13

219

0.638

1

1.000

126

0.574

0

ACIAD1921

ppiB

peptidyl-prolyl cis-trans isomerase precursor (PPIase) (Rotamase)

5.2.1.8

54

0.741

1423

0.927

127

0.573

0

ACIAD0225

dinP

DNA polymerase IV, devoid of proofreading, damage-inducible protein P

2.7.7.7

140

0.673

358

0.973

128

0.573

0

ACIAD0068

ptk

tyrosine-protein kinase, autophosphorylates

2.7.10.2

143

0.672

358

0.973

129

0.573

0

ACIAD3257

murI

glutamate racemase

5.1.1.3

141

0.673

358

0.973

130

0.573

0

ACIAD2860

carA

carbamoyl-phosphate synthase, small chain

6.3.5.5

145

0.671

358

0.973

131

0.572

0

ACIAD2052

putative transcriptional regulator (YebC like)

144

0.671

358

0.973

132

0.572

0

ACIAD3587

purC

phosphoribosylaminoimidazole-succinocarboxamide synthase

6.3.2.6

147

0.670

358

0.973

133

0.571

0

ACIAD2561

putative GTP-binding protein (Obg)

148

0.669

358

0.973

134

0.570

0

ACIAD2365

msbA

lipid transport protein, flippase (ABC superfamily, membrane (N-terminal), atp_bind (C-terminal))

226

0.633

1

1.000

135

0.570

0

ACIAD0660

murA

UDP-N-acetylglucosamine 1-carboxyvinyltransferase (Enoylpyruvate transferase) (UDP-N-acetylglucosamine enolpyruvyl transferase) (EPT)

2.5.1.7

149

0.669

358

0.973

136

0.570

0

ACIAD0535

clpX

ATP-dependent Clp protease ATP-binding subunit

115

0.688

825

0.960

137

0.570

0

ACIAD1672

mtlD

mannitol-1-phosphate 5-dehydrogenase

1.1.1.17

151

0.668

358

0.973

138

0.569

0

ACIAD3196

rpsK

30S ribosomal protein S11

153

0.667

358

0.973

139

0.569

0

ACIAD3208

rplX

50S ribosomal protein L24

152

0.668

358

0.973

140

0.569

0

ACIAD3038

rho

transcription termination factor

154

0.667

358

0.973

141

0.568

0

ACIAD3310

rplS

50S ribosomal protein L19

160

0.665

358

0.973

142

0.567

0

ACIAD2071

putative GTP-binding protein

164

0.665

358

0.973

143

0.566

0

ACIAD0151

guaA

GMP synthetase (glutamine aminotransferase)

6.3.5.2, 6.3.5.2

163

0.665

358

0.973

144

0.566

0

ACIAD2933

putative tRNA/rRNA methyltransferase

2.1.1.34

168

0.663

358

0.973

145

0.565

0

ACIAD2368

gidB

glucose-inhibited division protein B (methyltransferase)

2.1.-.-

169

0.662

358

0.973

146

0.564

0

ACIAD1385

recA

DNA strand exchange and recombination protein with protease and nuclease activity.

170

0.661

358

0.973

147

0.564

0

ACIAD0463

leuC

3-isopropylmalate dehydratase (isomerase), subunit with LeuD

4.2.1.33

78

0.721

1370

0.931

148

0.563

0

ACIAD1318

putative phosphohistidine phosphatase

3.1.3.-

251

0.624

1

1.000

149

0.562

0

ACIAD3216

rplB

50S ribosomal protein L2

171

0.659

358

0.973

150

0.562

0

ACIAD3324

gmk

guanylate kinase

2.7.4.8

172

0.659

358

0.973

151

0.562

0

ACIAD1062

ppk

polyphosphate kinase

2.7.4.1

173

0.658

358

0.973

152

0.561

0

ACIAD3204

rplF

50S ribosomal protein L6

175

0.657

358

0.973

153

0.560

0

ACIAD2584

lepA

GTP-binding protein

174

0.657

733

0.972

154

0.559

0

ACIAD0271

ftsW

cell division protein, stabililzes FtsZ ring

91

0.702

1052

0.940

155

0.559

0

ACIAD2635

purN

phosphoribosylglycinamide formyltransferase 1

2.1.2.2

139

0.673

825

0.960

156

0.558

0

ACIAD2557

dusB

tRNA-dihydrouridine synthase B

1.-.-.-

178

0.654

358

0.973

157

0.558

0

ACIAD1903

moaCB

bifunctional protein [Includes: molybdenum cofactor biosynthesis protein C; molybdenum cofactor biosynthesis protein B]

263

0.620

1

1.000

158

0.558

0

ACIAD0185

atpA

membrane-bound ATP synthase , F1 sector, alpha-subunit

7.1.2.2

180

0.654

358

0.973

159

0.557

0

ACIAD3313

rpsP

30S ribosomal protein S16

181

0.654

358

0.973

160

0.557

0

ACIAD3325

rpoZ

RNA polymerase, omega subunit

2.7.7.6

182

0.654

358

0.973

161

0.557

0

ACIAD1100

putative methyltransferase

186

0.652

358

0.973

162

0.556

0

ACIAD0565

putative GTP-binding protein EngA

188

0.651

358

0.973

163

0.555

0

ACIAD3238

putative hydrolase

274

0.616

1

1.000

164

0.554

0

ACIAD3572

nusB

transcription termination, L factor (N utilization substance protein B)

190

0.651

358

0.973

165

0.554

0

ACIAD3119

putative ribosome biogenesis GTPase RsgA

158

0.666

825

0.960

166

0.552

0

ACIAD2853

ftsH

cell division protein

3.4.24.-

193

0.650

733

0.972

167

0.552

0

ACIAD2348

cmk

cytidylate kinase (cytidine monophosphate (CMP) kinase)

2.7.4.25

157

0.666

825

0.960

168

0.552

0

ACIAD1405

iscR

repressor of the iscRSUA operon, involved in assembly of Fe-S clusters

106

0.694

1052

0.940

169

0.552

0

ACIAD3213

rpsC

30S ribosomal protein S3

196

0.647

358

0.973

170

0.551

0

ACIAD3575

glmU

bifunctional protein [Includes: UDP-N-acetylglucosamine pyrophosphorylase (N-acetylglucosamine-1-phosphate uridyltransferase); Glucosamine-1-phosphate N-acetyltransferase ]

2.7.7.23, 2.3.1.57

198

0.647

358

0.973

171

0.551

0

ACIAD1084

aceA

isocitrate lyase

4.1.3.1

283

0.611

1

1.000

172

0.550

0

ACIAD3209

rplN

50S ribosomal protein L14

201

0.646

358

0.973

173

0.550

0

ACIAD0209

putative Rossmann-fold nucleotide-binding protein involved in DNA uptake (Smf)

202

0.645

733

0.972

174

0.548

0

ACIAD3637

fmt

methionyl-tRNA formyltransferase

2.1.2.9

204

0.643

358

0.973

175

0.548

0

ACIAD2089

dnaE

DNA polymerase III, alpha chain

2.7.7.7

206

0.642

358

0.973

176

0.547

0

ACIAD2458

glnA

glutamine synthetase

6.3.1.2

211

0.641

358

0.973

177

0.546

0

ACIAD0677

putative glycoprotein endopeptidase metalloprotease

3.4.-.-

89

0.706

1423

0.927

178

0.546

0

ACIAD2580

era

GTP-binding protein,16S rRNA-binding,ribosome-associated GTPase

212

0.639

358

0.973

179

0.544

0

ACIAD1945

murB

UDP-N-acetylenolpyruvoylglucosamine reductase, FAD-binding

1.3.1.98

216

0.638

358

0.973

180

0.544

0

ACIAD1906

moaA

molybdopterin biosynthesis, protein A

298

0.604

1

1.000

181

0.544

0

ACIAD1357

ilvA

Threonine dehydratase biosynthetic (Threonine deaminase)

4.3.1.19

299

0.604

1

1.000

182

0.544

0

ACIAD0352

yqgF

holliday junction resolvase yqgF-like

3.1.-.-

214

0.639

358

0.973

183

0.544

0

ACIAD2852

folP

7,8-dihydropteroate synthase

2.5.1.15

122

0.683

1189

0.939

184

0.543

0

ACIAD3194

rpoA

RNA polymerase, alpha subunit

2.7.7.6

221

0.637

358

0.973

185

0.543

0

ACIAD1996

ispF

2C-methyl-D-erythritol 2,4-cyclodiphosphate synthase

4.6.1.12

126

0.681

1052

0.940

186

0.542

0

ACIAD1408

hupB

DNA-binding protein HU-beta

177

0.655

825

0.960

187

0.542

0

ACIAD3058

ptsO

phosphocarrier protein (HPr-like) NPr, nitrogen related, exchanges phosphate with Enzyme I

185

0.652

825

0.960

188

0.541

0

ACIAD2850

glxK

glycerate kinase

2.7.1.31

183

0.653

825

0.960

189

0.541

0

ACIAD2614

ruvA

holliday junction helicase subunit A

223

0.635

358

0.973

190

0.541

0

ACIAD1081

putative hemolysin-related protein

225

0.635

358

0.973

191

0.541

0

ACIAD0657

rpoN

RNA polymerase sigma-54 factor

93

0.701

1721

0.926

192

0.541

0

ACIAD1900

modB

molybdate transport protein (ABC superfamily, membrane)

129

0.681

1189

0.939

193

0.540

0

ACIAD2347

rpsA

30S ribosomal protein S1

229

0.633

358

0.973

194

0.539

0

ACIAD0279

phoU

transcriptional repressor for high affinity phosphate uptake

232

0.632

358

0.973

195

0.539

0

ACIAD3215

rpsS

30S ribosomal protein S19

228

0.633

358

0.973

196

0.539

0

ACIAD3247

dxs

1-deoxyxylulose-5-phosphate synthase

2.2.1.7

191

0.650

825

0.960

197

0.539

0

ACIAD0514

folA

dihydrofolate reductase

1.5.1.3

233

0.632

358

0.973

198

0.538

0

ACIAD2234

mrcB

bifunctional protein [Includes penicillin-insensitive transglycosylase; penicillin-sensitive transpeptidase] (penicillin-binding protein 1B)

2.4.1.129, 3.4.-.-

237

0.630

358

0.973

199

0.537

0

ACIAD1308

thiG

thiamine biosynthesis protein, thiazole moiety

237

0.630

358

0.973

200

0.537

0

ACIAD0703

typA

GTP-binding elongation factor family protein

243

0.627

358

0.973

201

0.535

0

ACIAD3350

gltB

glutamate synthase large chain precursor

1.4.1.13

107

0.693

1721

0.926

202

0.535

0

ACIAD2909

pth

peptidyl-tRNA hydrolase

3.1.1.29

248

0.626

358

0.973

203

0.534

0

ACIAD0930

glpK

glycerol kinase

2.7.1.30

318

0.594

1

1.000

204

0.534

0

ACIAD0182

atpE

membrane-bound ATP synthase, F0 sector, subunit c

7.1.2.2

246

0.627

358

0.973

205

0.534

0

ACIAD0472

infA

protein chain initiation factor IF-1

250

0.625

358

0.973

206

0.533

0

ACIAD2950

valS

valyl-tRNA synthetase

6.1.1.9

210

0.641

825

0.960

207

0.532

0

ACIAD0887

rimI

ribosomal-protein-alanine acetyltransferase (Acetylating enzyme for N-terminal of ribosomal protein S18)

2.3.1.267

325

0.589

1

1.000

208

0.531

0

ACIAD3455

uvrA

excinuclease ABC subunit A

254

0.624

358

0.973

209

0.531

0

ACIAD2566

rarD

chloramphenicol-sensitive protein

90

0.704

2233

0.915

210

0.530

0

ACIAD2411

molybdopterin biosynthesis protein (moeB) OR thiamin-thiazole moiety synthesis (thiF)

327

0.589

1

1.000

211

0.530

0

ACIAD1901

modA

molybdate transport protein (ABC superfamily, peri_bind)

155

0.667

1189

0.939

212

0.530

0

ACIAD2838

groEL

chaperone Hsp60, peptide-dependent ATPase, heat shock protein

217

0.638

825

0.960

213

0.529

0

ACIAD2400

copA

Copper-exporting P-type ATPase A

330

0.588

1

1.000

214

0.529

0

ACIAD0515

thyA

thymidylate synthase (TS) (TSase)

2.1.1.45

259

0.621

358

0.973

215

0.529

0

ACIAD0510

msrA

peptide methionine sulfoxide reductase (Protein- methionine-S-oxide reductase) (Peptide Met(O) reductase)

1.8.4.11

328

0.588

1

1.000

216

0.529

0

ACIAD2422

conserved hypothetical protein

162

0.665

1189

0.939

217

0.528

0

ACIAD1372

pyrH

uridylate kinase

2.7.4.-

262

0.620

358

0.973

218

0.528

0

ACIAD1266

ilvD

dihydroxy-acid dehydratase

4.2.1.9

123

0.682

1423

0.927

219

0.528

0

ACIAD0235

fadD

acyl-CoA synthetase (long-chain-fatty-acid--CoA ligase)

6.2.1.3

339

0.586

1

1.000

220

0.528

0

ACIAD3561

rhdA

thiosulfate sulfurtransferase (Rhodanese-like protein)

2.8.1.1

336

0.586

1

1.000

221

0.528

0

ACIAD3131

putative phosphoesterase (PHP family)

268

0.618

358

0.973

222

0.527

0

ACIAD3065

putative nucleoside triphosphate pyrophosphohydrolase (MazG)

222

0.636

825

0.960

223

0.527

0

ACIAD1999

ispD

2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase

2.7.7.60

166

0.664

1189

0.939

224

0.527

0

ACIAD3197

rpsM

30S ribosomal protein S13

265

0.619

358

0.973

225

0.527

0

ACIAD2938

rpmA

50S ribosomal protein L27

271

0.618

358

0.973

226

0.526

0

ACIAD3353

aroB

3-dehydroquinate synthase

4.2.3.4

347

0.584

1

1.000

227

0.526

0

ACIAD3158

putative tRNA-i(6)A37 modification enzyme (MiaB)

227

0.633

825

0.960

228

0.525

0

ACIAD1135

nudC

NADH pyrophosphatase (NUDIX hydrolase family)

3.6.1.22

142

0.672

1370

0.931

229

0.525

0

ACIAD0187

atpD

membrane-bound ATP synthase , F1 sector, beta-subunit

7.1.2.2

273

0.616

358

0.973

230

0.525

0

ACIAD0364

secG

preprotein translocase IISP family, auxillary membrane component

276

0.615

358

0.973

231

0.524

0

ACIAD3300

putative FAD/FMN-containing dehydrogenase

354

0.582

1

1.000

232

0.524

0

ACIAD2008

pepN

aminopeptidase N

3.4.11.2

357

0.581

1

1.000

233

0.523

0

ACIAD1865

putative transcriptional regulator (ArsR family)

356

0.581

1

1.000

234

0.523

0

ACIAD3594

conserved hypothetical protein; putative diguanylate cyclase/phosphodiesterase

127

0.681

1921

0.924

235

0.523

0

ACIAD0661

hisG

ATP-phosphoribosyltransferase

2.4.2.17

361

0.580

1

1.000

236

0.522

0

ACIAD0245

amtB

ammonium transport protein (Amt family)

363

0.580

1

1.000

237

0.522

0

ACIAD3210

rpsQ

30S ribosomal protein S17

281

0.612

358

0.973

238

0.522

0

ACIAD3102

ilvC

acetohydroxy acid isomeroreductase and 2-dehydropantoate 2-reductase

1.1.1.86, 1.1.1.169

176

0.656

1189

0.939

239

0.521

0

ACIAD2213

gloA

lactoylglutathione lyase

4.4.1.5

364

0.579

1

1.000

240

0.521

0

ACIAD0407

hslO

heat shock protein Hsp33

138

0.673

1423

0.927

241

0.521

0

ACIAD3388

ompR

two-component response regulator

108

0.693

2233

0.915

242

0.521

0

ACIAD3064

putative DNA uptake protein and/or related DNA-binding protein

285

0.610

358

0.973

243

0.520

0

ACIAD2615

ruvB

holliday junction helicase, subunit B

184

0.653

1052

0.940

244

0.520

0

ACIAD2373

hfq

host factor I for bacteriophage Q beta replication, a growth-related protein

121

0.685

2199

0.917

245

0.518

0

ACIAD0469

leuB

3-isopropylmalate dehydrogenase

1.1.1.85

372

0.576

1

1.000

246

0.518

0

ACIAD2660

lysA

diaminopimelate decarboxylase

4.1.1.20

192

0.650

1052

0.940

247

0.517

0

ACIAD2613

dgt

deoxyguanosinetriphosphate triphosphohydrolase (dGTPase) (dGTP triphosphohydrolase)

3.1.5.1

378

0.575

1

1.000

248

0.517

0

ACIAD0898

putative outer membrane protein

252

0.624

825

0.960

249

0.517

0

ACIAD0838

conserved hypothetical protein; putative membrane protein

150

0.668

1423

0.927

250

0.517

0

ACIAD0402

pnp

polyribonucleotide nucleotidyltransferase (Polynucleotide phosphorylase) (PNPase)

2.7.7.8

293

0.607

358

0.973

251

0.517

0

ACIAD0186

atpG

membrane-bound ATP synthase , F1 sector, gamma-subunit

7.1.2.2

194

0.649

1052

0.940

252

0.517

0

ACIAD3036

ppx

exopolyphosphatase (ExopolyPase) (Metaphosphatase)

3.6.1.11

195

0.648

1052

0.940

253

0.516

0

ACIAD1253

alaS

alanyl-tRNA synthetase

6.1.1.7

257

0.623

825

0.960

254

0.516

0

ACIAD2934

cysG

multifunctional protein [Includes: Uroporphyrin-III C-methyltransferase (Urogen III methylase) (SUMT) (Uroporphyrinogen III methylase) (UROM); Precorrin-2 oxidase ; Ferrochelatase ] (Siroheme synthase)

2.1.1.107, 1.3.1.76, 4.99.1.4

385

0.573

1

1.000

255

0.515

0

ACIAD2612

purL

phosphoribosylformylglycinamidine synthase (FGAM synthase) (FGAMS) (Formylglycinamide ribotide amidotransferase) (FGARAT) (Formylglycinamide ribotide synthetase)

6.3.5.3

384

0.573

1

1.000

256

0.515

0

ACIAD3386

putative transcriptional accessory protein

120

0.686

2399

0.913

257

0.515

0

ACIAD2430

rpsF

30S ribosomal protein S6

296

0.605

733

0.972

258

0.514

0

ACIAD1389

rpsT

30S ribosomal protein S20

300

0.604

358

0.973

259

0.514

0

ACIAD0444

putative transcriptional regulator

161

0.665

1423

0.927

260

0.514

0

ACIAD0802

putative bicyclomycin/multidrug transport protein (MFS superfamily)

167

0.663

1423

0.927

261

0.513

0

ACIAD0342

pgsA

CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase (Phosphatidylglycerophosphate synthase) (PGP synthase)

2.7.8.5

305

0.602

358

0.973

262

0.513

0

ACIAD3306

conserved hypothetical protein; putative membrane protein

159

0.665

1721

0.926

263

0.513

0

ACIAD3365

murE

UDP-N-acetylmuramoylalanyl-D-glutamate-2, 6-diaminopimelate ligase

6.3.2.13

199

0.646

1189

0.939

264

0.513

0

ACIAD3503

guaB

IMP dehydrogenase

1.1.1.205

304

0.603

733

0.972

265

0.513

0

ACIAD1323

purF

amidophosphoribosyltransferase

2.4.2.14

400

0.567

1

1.000

266

0.510

0

ACIAD0833

putative 5'-adenylylsulfate reductase (APS reductase) (cysH-like)

1.8.99.2

399

0.567

1

1.000

267

0.510

0

ACIAD0632

putative glycerophosphodiester phosphodiesterase

3.1.4.46

404

0.566

1

1.000

268

0.510

0

ACIAD3599

putative transcriptional regulator; putative detoxification transcriptional regulator

208

0.642

1189

0.939

269

0.510

0

ACIAD1215

pstB

high-affinity phosphate transport protein (ABC superfamily, atp_bind)

311

0.596

358

0.973

270

0.508

0

ACIAD0284

algZ

alginate biosynthesis protein

215

0.638

1052

0.940

271

0.508

0

ACIAD3511

ftsZ

cell division protein,tubulin-like GTP-binding protein and GTPase, forms circumferential ring in cell division and participates in the septum formation

313

0.596

358

0.973

272

0.508

0

ACIAD3371

gltX

glutamyl-tRNA synthetase

6.1.1.17, 6.1.1.24

316

0.595

358

0.973

273

0.507

0

ACIAD1650

npdA

NAD-dependent deacetylase (Regulatory protein sirtuin family)

3.5.1.-

410

0.563

1

1.000

274

0.506

0

ACIAD3206

rpsN

30S ribosomal protein S14

317

0.594

358

0.973

275

0.506

0

ACIAD2897

rluD

ribosomal large subunit pseudouridine synthase D (Pseudouridylate synthase) (Uracil hydrolyase)

4.2.1.70

290

0.609

825

0.960

276

0.505

0

ACIAD2633

putative permease (PerM family)

287

0.610

825

0.960

277

0.505

0

ACIAD2376

putative ATPase with strong ADP affinity

323

0.592

358

0.973

278

0.504

0

ACIAD1916

fdhD

formate dehydrogenase formation protein

1.17.1.9

420

0.560

1

1.000

279

0.504

0

ACIAD1072

cysD

sulfate adenylyltransferase subunit 2 (Sulfate adenylate transferase) (SAT) (ATP-sulfurylase small subunit)

2.7.7.4

114

0.688

2714

0.902

280

0.504

0

ACIAD1059

putative ABC transporter permease

322

0.593

733

0.972

281

0.504

0

ACIAD0726

bfmR

response regulator in two-component regulatory system (bfmR/bfmS)

291

0.609

825

0.960

282

0.504

0

ACIAD2925

rpoD

sigma D (sigma 70) factor of RNA polymerase , major sigma factor during exponential growth

297

0.605

825

0.960

283

0.501

0

ACIAD2589

conserved hypothetical protein; putative periplasmic solute-binding protein

240

0.629

1052

0.940

284

0.501

0

ACIAD2061

gltI

glutamate/aspartate transport protein (ABC superfamily, peri_bind)

329

0.588

358

0.973

285

0.501

0

ACIAD0544

gntT

high-affinity gluconate permease (GntP family)

335

0.587

358

0.973

286

0.500

0

ACIAD0242

magnesium chelatase, competence related protein (ComM)

341

0.586

358

0.973

287

0.499

0

ACIAD3054

infC

protein chain initiation factor IF-3

346

0.585

358

0.973

288

0.498

0

ACIAD2433

dnaB

replicative DNA helicase;chromosome replication, chain elongation

343

0.585

358

0.973

289

0.498

0

ACIAD1314

rhlB

ATP-dependent RNA helicase (DEAD box)

218

0.638

1370

0.931

290

0.498

0

ACIAD1302

trmB

tRNA(guanine-7)methyltransferase

2.1.1.33

344

0.585

358

0.973

291

0.498

0

ACIAD0003

recF

DNA replication, recombinaison and repair protein

344

0.585

358

0.973

292

0.498

0

ACIAD2657

xerC

site-specific tyrosine recombinase

444

0.552

1

1.000

293

0.497

0

ACIAD0746

putative transcriptional regulator (LysR family)

205

0.643

1423

0.927

294

0.497

0

ACIAD0247

ribD

bifunctional protein [Includes: diaminohydroxyphosphoribosylaminopyrimidine deaminase (Riboflavin-specific deaminase); 5-amino-6-(5- phosphoribosylamino)uracil reductase (HTP reductase) ]

3.5.4.26, 1.1.1.193

207

0.642

1423

0.927

295

0.497

0

ACIAD1245

add

adenosine deaminase

3.5.4.4

235

0.630

1297

0.935

296

0.496

0

ACIAD0871

fabG

3-oxoacyl-[acyl-carrier-protein] reductase

1.1.1.100

449

0.551

1

1.000

297

0.496

0

ACIAD3212

rplP

50S ribosomal protein L16

360

0.581

358

0.973

298

0.495

0

ACIAD3619

dapB

4-hydroxy-tetrahydrodipicolinate reductase

1.17.1.8

253

0.624

1189

0.939

299

0.495

0

ACIAD1252

lysC

aspartate kinase

2.7.2.4

365

0.579

358

0.973

300

0.494

0

ACIAD0384

ubiE

S-adenosylmethionine : 2-DMK methyltransferase and 2-octaprenyl-6-methoxy-1,4-benzoquinone methylase

2.1.1.-

200

0.646

2005

0.921

301

0.494

0

ACIAD2463

trpC

indole-3-glycerol phosphate synthase (IGPS)

4.1.1.48

220

0.638

1423

0.927

302

0.493

0

ACIAD2429

cyoE

protoheme IX farnesyltransferase (heme O biosynthesis)

2.5.1.-

458

0.548

1

1.000

303

0.493

0

ACIAD0367

Putative ribosome maturation factor RimP

314

0.595

825

0.960

304

0.493

0

ACIAD3042

pheS

phenylalanyl-tRNA synthetase, alpha-subunit

6.1.1.20

267

0.618

1052

0.940

305

0.492

0

ACIAD3013

rpsI

30S ribosomal protein S9

367

0.578

358

0.973

306

0.492

0

ACIAD1902

moeA

molybdopterin biosynthesis protein

465

0.547

1

1.000

307

0.492

0

ACIAD0900

rep

ATP-dependent DNA helicase

3.6.1.-

368

0.578

358

0.973

308

0.492

0

ACIAD0466

leuD

3-isopropylmalate isomerase (dehydratase), subunit with LeuC

4.2.1.33

264

0.619

1189

0.939

309

0.492

0

ACIAD1637

antibiotic resistance protein (acepita)

369

0.577

733

0.972

310

0.491

0

ACIAD2427

cyoC

cytochrome o ubiquinol oxidase subunit III

1.10.3.-

203

0.643

2104

0.920

311

0.490

0

ACIAD2283

metF

5,10-methylenetetrahydrofolate reductase

1.5.1.20

376

0.575

358

0.973

312

0.490

0

ACIAD2079

glnD

uridylyltransferase

2.7.7.59

230

0.633

1423

0.927

313

0.489

0

ACIAD2018

acoD

Acetaldehyde dehydrogenase 2 (Acetaldehyde dehydrogenase II) (ACDH-II)

1.2.1.3

134

0.678

2819

0.896

314

0.489

0

ACIAD0636

trpB

tryptophan synthase beta chain

4.2.1.20

373

0.576

733

0.972

315

0.489

0

ACIAD0551

nagZ

beta-N-acetyl-D-glucosaminidase

3.2.1.52

324

0.591

825

0.960

316

0.489

0

ACIAD0004

gyrB

DNA gyrase, subunit B (type II topoisomerase)

5.6.2.2

379

0.573

358

0.973

317

0.489

0

ACIAD3236

putative DNA transformation protein (ComF)

277

0.614

1052

0.940

318

0.489

0

ACIAD3302

serA

D-3-phosphoglycerate dehydrogenase

1.1.1.95

480

0.543

1

1.000

319

0.489

0

ACIAD2581

rnc

ribonuclease III, ds RNA

3.1.26.3

380

0.573

358

0.973

320

0.488

0

ACIAD3396

hisH

imidazole glycerol phosphate synthetase, glutamine amidotransferase subunit

4.3.2.10

234

0.631

1423

0.927

321

0.488

0

ACIAD0881

rpsL

30S ribosomal protein S12

387

0.571

358

0.973

322

0.487

0

ACIAD0829

putative Maf-like protein

280

0.612

1052

0.940

323

0.487

0

ACIAD3169

putative transcriptional regulator (LysR family)

235

0.630

1721

0.926

324

0.486

0

ACIAD2659

dapF

diaminopimelate epimerase

5.1.1.7

242

0.628

1423

0.927

325

0.486

0

ACIAD1369

glnL

sensory kinase (soluble) in two-component regulatory system

197

0.647

2399

0.913

326

0.486

0

ACIAD0191

putative aldose 1-epimerase family protein

286

0.610

1052

0.940

327

0.486

0

ACIAD0114

dadR

transcriptional regulator for dadAX gene cluster (AsnC family)

489

0.540

1

1.000

328

0.486

0

ACIAD2973

kdpE

regulator of kdp operon (transcriptional effector)

224

0.635

2005

0.921

329

0.485

0

ACIAD2206

efp

elongation factor P

393

0.569

358

0.973

330

0.485

0

ACIAD1743

putative oxydoreductase protein, zinc-containing (quinone oxidoreductase, NADPH dependent)

1.6.5.-

239

0.630

1876

0.925

331

0.485

0

ACIAD0102

galE

UDP-glucose 4-epimerase (Galactowaldenase) (UDP-galactose 4-epimerase)

5.1.3.2

289

0.609

1052

0.940

332

0.485

0

ACIAD0107

lldR

transcriptional repressor for L-lactate utilization (GntR family)

244

0.627

1721

0.926

333

0.484

0

ACIAD0010

putative chaperone involved in Fe-S cluster assembly and activation (HesB-like)

249

0.626

1423

0.927

334

0.484

0

ACIAD3681

oxaA

Inner membrane protein (IMP) integration factor; binds TM regions of nascent IMPs; required for Sec-independent IMP integration; associated with the Sec translocase

391

0.570

733

0.972

335

0.484

0

ACIAD2290

cydA

cytochrome d terminal oxidase, polypeptide subunit I

1.10.3.-

245

0.627

1721

0.926

336

0.483

0

ACIAD1063

estR

esterase operon transcriptional regulator (LysR family)

401

0.567

358

0.973

337

0.483

0

ACIAD0863

scpA

chromosome condensation and partitioning factor

292

0.607

1052

0.940

338

0.483

0

ACIAD0474

truA

tRNA-pseudouridine synthase I

4.2.1.70

398

0.567

358

0.973

339

0.483

0

ACIAD3576

glmS

glucosamine--fructose-6-phosphate aminotransferase

2.6.1.16

397

0.567

358

0.973

340

0.483

0

ACIAD3160

putative metalloprotease ybeY-like

3.4.24.-

405

0.566

358

0.973

341

0.482

0

ACIAD0064

putative virulence factor MviN family (multidrug/oligosaccharidyl-lipid/polysaccharide exporter superfamily)

355

0.582

825

0.960

342

0.482

0

ACIAD3031

conserved hypothetical protein; putative integral membrane resistance protein

403

0.566

733

0.972

343

0.481

0

ACIAD2342

conserved hypothetical protein; putative transcriptional regulator

359

0.581

825

0.960

344

0.481

0

ACIAD1241

putative sulfate transporter

512

0.533

1

1.000

345

0.480

0

ACIAD1197

conserved hypothetical protein

507

0.533

1

1.000

346

0.480

0

ACIAD0276

thiC

hydroxymethylpyrimidine moiety synthesis in thiamin biosynthesis

302

0.603

1052

0.940

347

0.480

0

ACIAD0828

mreD

rod shape-determining protein

411

0.563

358

0.973

348

0.479

0

ACIAD3611

tag

3-methyl-adenine DNA glycosylase I, constitutive

3.2.2.20

260

0.621

1721

0.926

349

0.479

0

ACIAD3021

putative carbon-nitrogen hydrolase

269

0.618

1423

0.927

350

0.478

0

ACIAD2997

putative transport protein (MFS superfamily)

518

0.531

1

1.000

351

0.478

0

ACIAD1225

dacC

D-ala-D-ala-carboxypeptidase; penicillin-binding protein 5 (precursor)

3.4.16.4

272

0.618

1423

0.927

352

0.478

0

ACIAD0244

glnK

regulatory protein, P-II 2, for nitrogen assimilation by glutamine synthetase, regulates GlnL (NRII) and GlnE (ATase)

266

0.618

1423

0.927

353

0.478

0

ACIAD3658

purK

phosphoribosylaminoimidazole carboxylase ATPase subunit

4.1.1.21

515

0.531

1

1.000

354

0.478

0

ACIAD2899

dnaG

DNA primase

2.7.7.-

417

0.560

358

0.973

355

0.477

0

ACIAD2644

conserved hypothetical protein

213

0.639

2518

0.911

356

0.477

0

ACIAD0826

mreC

rod shape-determining protein

307

0.599

1052

0.940

357

0.477

0

ACIAD1778

fecI

alternative RNAP sigma factor required for fecA promoter recognition and ferric citrate transport; activated by FecR

419

0.560

733

0.972

358

0.476

0

ACIAD1604

mmsA

methylmalonate-semialdehyde dehydrogenase, oxidoreductase protein

1.2.1.27

231

0.632

2233

0.915

359

0.476

0

ACIAD0658

putative sigma(54) modulation protein RpoX

423

0.558

358

0.973

360

0.476

0

ACIAD0272

putative glutamyl t-RNA synthetase

6.1.1.17

309

0.598

1052

0.940

361

0.476

0

ACIAD3012

rplM

50S ribosomal protein L13

381

0.573

825

0.960

362

0.475

0

ACIAD1386

hslR

heat shock protein 15

278

0.614

1423

0.927

363

0.475

0

ACIAD1058

putative transport protein (ABC superfamily, atp_bind)

428

0.558

358

0.973

364

0.475

0

ACIAD3078

pntB

pyridine nucleotide transhydrogenase, beta subunit

1.6.1.2

275

0.615

1876

0.925

365

0.474

0

ACIAD2996

putative hemolysin III (HLY-III)

311

0.596

1052

0.940

366

0.474

0

ACIAD2903

ispE

4-diphosphocytidyl-2-C-methyl-D-erythritol kinase (CMK) (4-(cytidine-5'-diphospho)-2-C-methyl-D-erythritol kinase)

2.7.1.148

310

0.597

1189

0.939

367

0.474

0

ACIAD0013

tyrS

tyrosyl-tRNA synthetase

6.1.1.1

432

0.557

358

0.973

368

0.474

0

ACIAD2443

prmA

methylation of 50S ribosomal subunit protein L11 (ribosomal protein L11 methyltransferase)

2.1.1.-

389

0.571

825

0.960

369

0.473

0

ACIAD1983

putative transporter transmembrane protein (magnesium transporter)

319

0.594

1052

0.940

370

0.473

0

ACIAD3563

dtd

D-tyrosyl tRNA(tyr) deacylase

3.1.-.-

315

0.595

1189

0.939

371

0.472

0

ACIAD0687

pcoA

copper resistance protein A precursor

443

0.552

358

0.973

372

0.471

0

ACIAD2861

carB

carbamoyl-phosphate synthase, large subunit

6.3.5.5

448

0.551

358

0.973

373

0.470

0

ACIAD2587

nadB

L-aspartate oxidase (quinolinate synthetase B)

1.4.3.16

547

0.521

1

1.000

374

0.469

0

ACIAD0285

algR

alginate biosynthesis regulatory protein

326

0.589

1052

0.940

375

0.469

0

ACIAD3055

thrS

threonyl-tRNA synthetase

6.1.1.3

457

0.549

358

0.973

376

0.468

0

ACIAD1214

pstA

high-affinity phosphate transport protein (ABC superfamily, membrane)

454

0.549

358

0.973

377

0.468

0

ACIAD0076

rmlB

dTDP-D-glucose-4,6-dehydratase

4.2.1.46

456

0.549

358

0.973

378

0.468

0

ACIAD1362

clpS

substrate modulator for ClpAP, directs protease activity towards aggregated proteins

284

0.611

2005

0.921

379

0.467

0

ACIAD0642

trpA

tryptophan synthase alpha chain

4.2.1.20

301

0.604

1423

0.927

380

0.467

0

ACIAD0160

putative transcriptional regulator (AraC family)

333

0.587

1052

0.940

381

0.467

0

ACIAD3104

ilvI

acetolactate synthase III, large subunit

2.2.1.6

334

0.587

1189

0.939

382

0.466

0

ACIAD1930

conserved hypothetical protein; putative Maf-like protein

256

0.623

2518

0.911

383

0.466

0

ACIAD3354

aroK

shikimate-kinase

2.7.1.71

340

0.586

1052

0.940

384

0.466

0

ACIAD3526

crc

catabolite repression control protein

559

0.518

1

1.000

385

0.466

0

ACIAD2313

putative nucleoid-associated protein (YbaB like)

348

0.584

1052

0.940

386

0.465

0

ACIAD1908

nasA

nitrate reductase, large subunit

1.7.99.4

564

0.516

1

1.000

387

0.465

0

ACIAD0884

fusA

protein chain elongation factor EF-G, GTP-binding

469

0.545

358

0.973

388

0.465

0

ACIAD0707

mutM

formamidopyrimidine-DNA glycosylase

3.2.2.23

306

0.602

1423

0.927

389

0.465

0

ACIAD2275

lipA

lipoate synthase

261

0.620

2518

0.911

390

0.464

0

ACIAD2028

aroC

chorismate synthase

4.2.3.5

472

0.545

358

0.973

391

0.464

0

ACIAD2940

ispB

octaprenyl-diphosphate synthase (Octaprenyl pyrophosphate synthetase) (OPP synthetase)

2.5.1.-

575

0.514

1

1.000

392

0.463

0

ACIAD1674

conserved hypothetical protein; putative transporter

475

0.544

733

0.972

393

0.463

0

ACIAD1248

rnhB

RNAse HII

3.1.26.4

571

0.515

1

1.000

394

0.463

0

ACIAD1113

rlmH

Ribosomal RNA large subunit methyltransferase H

2.1.1.-

351

0.583

1189

0.939

395

0.463

0

ACIAD0429

norM

multidrug resistance protein (Na(+)/drug antiporter) (Multidrug- efflux transporter)

425

0.558

825

0.960

396

0.463

0

ACIAD3193

rplQ

50S ribosomal protein L17

482

0.543

358

0.973

397

0.463

0

ACIAD3217

rplW

50S ribosomal protein L23

572

0.515

1

1.000

398

0.463

0

ACIAD2832

putative transglycosylase

430

0.557

825

0.960

399

0.462

0

ACIAD2509

bdhA

3-hydroxybutyrate dehydrogenase

1.1.1.30

580

0.513

1

1.000

400

0.462

0

ACIAD1662

cysK

subunit of cysteine synthase A and O-acetylserine sulfhydrolase A, PLP-dependent enzyme

2.5.1.47

487

0.542

358

0.973

401

0.462

0

ACIAD0098

putative UDP-glucose lipid carrier transferase/glucose-1-phosphate transferase in colanic acid gene cluster (WcaJ)

2.7.-.-

427

0.558

825

0.960

402

0.462

0

ACIAD3528

conserved hypothetical protein; putative arsenate reductase and related

358

0.581

1189

0.939

403

0.462

0

ACIAD2361

holB

DNA polymerase III, delta prime subunit

2.7.7.7

303

0.603

2005

0.921

404

0.461

0

ACIAD1116

folN

5-formyltetrahydrofolate cyclo-ligase

6.3.3.2

587

0.512

1

1.000

405

0.461

0

ACIAD3246

suhB

inositol-1-monophosphatase (IMPase) (Inositol-1- phosphatase) (I-1-Pase)

3.1.3.25

431

0.557

825

0.960

406

0.461

0

ACIAD3103

ilvH

acetolactate synthase isozyme III, small subunit

2.2.1.6

362

0.580

1189

0.939

407

0.460

0

ACIAD3061

panB

3-methyl-2-oxobutanoate hydroxymethyltransferase (Ketopantoate hydroxymethyltransferase)

2.1.2.11

436

0.555

825

0.960

408

0.460

0

ACIAD2844

glpD

glycerol-3-phosphate dehydrogenase

1.1.5.3

255

0.623

2658

0.906

409

0.460

0

ACIAD1309

thiS

C-terminally thiocarboxylated form is intermediate sulfur donor in thiazole formation; part of ThiF/ThiS complex; complexes with ThiG also

493

0.540

358

0.973

410

0.460

0

ACIAD3088

putative tRNA threonylcarbamoyladenosine dehydratase (tcdA)

370

0.577

1052

0.940

411

0.459

0

ACIAD3023

ohr

organic hydroperoxide resistance protein

247

0.626

2714

0.902

412

0.459

0

ACIAD2474

hemE

uroporphyrinogen decarboxylase

4.1.1.37

288

0.609

2233

0.915

413

0.459

0

ACIAD2236

putative bifunctional protein [Includes: dGTP-pyrophosphohydrolase; thiamine phosphate synthase]

371

0.576

1052

0.940

414

0.459

0

ACIAD0868

conserved hypothetical protein

491

0.540

733

0.972

415

0.459

0

ACIAD0861

putative ribosomal large subunit pseudouridine synthase B (Pseudouridylate synthase) (Uracil hydrolyase)

4.2.1.70

495

0.539

358

0.973

416

0.459

0

ACIAD0691

sugE

suppressor of gro

320

0.593

1423

0.927

417

0.459

0

ACIAD3606

mutY

A/G specific adenine glycosylase

3.2.2.-

492

0.540

733

0.972

418

0.459

0

ACIAD3106

leuS

leucyl-tRNA synthetase

6.1.1.4

445

0.552

825

0.960

419

0.458

0

ACIAD1316

putative nitroreductase

279

0.613

2518

0.911

420

0.458

0

ACIAD0454

ptsP

phosphoenolpyruvate-protein phosphotransferase

2.7.3.9

353

0.583

1297

0.935

421

0.458

0

ACIAD3172

conserved hypothetical protein; putative fumarylacetoacetate hydrolase family protein

602

0.507

1

1.000

422

0.457

0

ACIAD1321

pyrD

dihydroorotate oxydase

1.3.98.1, 1.3.5.2

603

0.507

1

1.000

423

0.457

0

ACIAD0452

putative acyl-CoA dehydrogenase (AidB)

1.3.99.-

601

0.507

1

1.000

424

0.457

0

ACIAD0966

putative amino acid transport protein (LysE family)

241

0.629

2770

0.898

425

0.456

0

ACIAD0727

bfmS

sensory histidine kinase in two-component regulatory system (bfmR/bfmS)

2.7.13.3

503

0.535

358

0.973

426

0.456

0

ACIAD0504

putative transcriptional regulator (TetR-family)

452

0.550

825

0.960

427

0.456

0

ACIAD0231

conserved hypothetical protein

294

0.606

2233

0.915

428

0.456

0

ACIAD3398

hisA

phosphoribosylformimino-5-aminoimidazole carboxamide isomerase

5.3.1.16

349

0.584

1370

0.931

429

0.456

0

ACIAD1330

conserved hypothetical protein

453

0.550

825

0.960

430

0.455

0

ACIAD0286

hemC

porphobilinogen deaminase (PBG) (Hydroxymethylbilane synthase) (HMBS) (Pre-uroporphyrinogen synthase)

2.5.1.61

386

0.572

1189

0.939

431

0.455

0

ACIAD3231

tesB

acyl-CoA thioesterase II

3.1.2.-

270

0.618

2695

0.904

432

0.455

0

ACIAD3037

trxA

thioredoxin

390

0.570

1052

0.940

433

0.454

0

ACIAD2070

metI

D- and L-methionine transport protein (ABC superfamily, membrane)

510

0.533

358

0.973

434

0.454

0

ACIAD3195

rpsD

30S ribosomal protein S4

460

0.548

825

0.960

435

0.454

0

ACIAD3449

ssb

ssDNA-binding protein controls activity of RecBCD nuclease

508

0.533

358

0.973

436

0.454

0

ACIAD2654

etfA

electron transfer flavoprotein alpha-subunit

620

0.504

1

1.000

437

0.453

0

ACIAD2291

cydB

cytochrome d terminal oxidase polypeptide subunit II

1.10.3.-

332

0.587

1721

0.926

438

0.453

0

ACIAD1630

cfa

cyclopropane-fatty-acyl-phospholipid synthase

2.1.1.79

331

0.588

1721

0.926

439

0.453

0

ACIAD0629

conserved hypothetical protein

295

0.605

2454

0.912

440

0.453

0

ACIAD3368

mraW

Ribosomal RNA small subunit methyltransferase H

2.1.1.-

509

0.533

733

0.972

441

0.453

0

ACIAD0921

conserved hypothetical protein; putative nucleoside-diphosphate sugar epimerases (SulA family)

321

0.593

2104

0.920

442

0.452

0

ACIAD2001

eno

enolase

4.2.1.11

476

0.544

825

0.960

443

0.451

0

ACIAD1910

nasD

nitrite reductase, large subunit, nucleotide- and Fe/S-cluster binding

1.7.1.4

352

0.583

1423

0.927

444

0.451

0

ACIAD0502

rpmB

50S ribosomal protein L28

522

0.530

358

0.973

445

0.451

0

ACIAD3654

dnaK

chaperone Hsp70 in DNA biosynthesis/cell division

525

0.529

358

0.973

446

0.451

0

ACIAD0101

pgi

glucose-6-phosphate isomerase

5.3.1.9

530

0.528

358

0.973

447

0.450

0

ACIAD2994

putative acetyl transferase

2.3.1.-

388

0.571

1297

0.935

448

0.449

0

ACIAD2101

putative 3-oxoacyl-[acyl-carrier-protein] synthase III

2.3.1.41

486

0.542

825

0.960

449

0.449

0

ACIAD1047

pit

phosphate transporter

649

0.499

1

1.000

450

0.449

0

ACIAD0704

mscL

mechanosensitive channel

533

0.528

733

0.972

451

0.449

0

ACIAD0589

putative SecYEG protein translocase auxillary subunit (YajC)

532

0.528

733

0.972

452

0.449

0

ACIAD3404

hisF

imidazole glycerol phosphate synthase, cyclase subunit

4.1.3.-

650

0.499

1

1.000

453

0.449

0

ACIAD2908

rplY

50S ribosomal protein L25

536

0.526

358

0.973

454

0.448

0

ACIAD1057

tesA

multifunctional protein [Includes: acyl-CoA thioesterase I; protease I; lysophospholipaseL(I)]

3.1.2.-, 3.4.21.-, 3.1.1.5

392

0.569

1297

0.935

455

0.448

0

ACIAD3470

msuE

NADH-dependent FMN reductase

1.5.1.-

655

0.498

1

1.000

456

0.448

0

ACIAD1132

conserved hypothetical protein

538

0.525

358

0.973

457

0.447

0

ACIAD3311

trmD

tRNA (guanine-1-)-methyltransferase.

2.1.1.-

496

0.538

825

0.960

458

0.446

0

ACIAD3034

tilS

tRNA(Ile)-lysidine synthetase

545

0.523

358

0.973

459

0.445

0

ACIAD2939

rplU

50S ribosomal protein L21

543

0.523

358

0.973

460

0.445

0

ACIAD3514

ftsQ

cell division protein (in growth of wall at septum)

421

0.559

1052

0.940

461

0.445

0

ACIAD2647

serC

3-phosphoserine aminotransferase

2.6.1.52

394

0.569

1370

0.931

462

0.444

0

ACIAD2639

comA

competence factor involved in DNA uptake

548

0.521

358

0.973

463

0.444

0

ACIAD2596

cysA

sulfate permease A protein, chromate resistance (ABC superfamily, atp_bind)

671

0.493

1

1.000

464

0.444

0

ACIAD1904

moaE

molybdopterin converting factor, large subunit

666

0.494

1

1.000

465

0.444

0

ACIAD0404

crcB

high-copy crc-csp restores normal chromosome condensation in presence of camphor or mukB mutations

542

0.523

733

0.972

466

0.444

0

ACIAD0275

aspP

adenosine diphosphate sugar pyrophosphatase (ADP-ribose pyrophosphatase)

3.6.1.13

667

0.494

1

1.000

467

0.444

0

ACIAD0967

iciA

inhibitor of replication initiation (transcriptional regulator of dnaA and argK (affects arginine transport) (LysR family))

282

0.611

2770

0.898

468

0.443

0

ACIAD2876

sucA

2-oxoglutarate decarboxylase E1 component of the 2-oxoglutarate dehydrogenase complex

1.2.4.2

366

0.578

2005

0.921

469

0.442

0

ACIAD2099

putative hydrolases or acyltransferases (alpha/beta hydrolase superfamily)

3.1.-.-

679

0.491

1

1.000

470

0.442

0

ACIAD2255

glyA

serine hydroxymethyltransferase

2.1.2.1

514

0.532

825

0.960

471

0.441

0

ACIAD1377

putative membrane-associated Zn-dependent proteases 1

513

0.532

825

0.960

472

0.441

0

ACIAD0099

galU

UTP-glucose-1-phosphate uridylyltransferase

2.7.7.9

438

0.554

1052

0.940

473

0.441

0

ACIAD3322

ispH

4-hydroxy-3-methylbut-2-enyl diphosphate reductase (also involved in penicillin tolerance and control of the stringent response. Seems to directly or indirectly interact with relA to maintain it in an inactive form during normal growth.)

1.17.7.4

439

0.554

1052

0.940

474

0.441

0

ACIAD2091

cysE

serine acetyltransferase

2.3.1.30

440

0.553

1052

0.940

475

0.440

0

ACIAD0493

topA

DNA topoisomerase type I, omega protein

5.6.2.1

569

0.515

358

0.973

476

0.439

0

ACIAD3150

putative ribosomal RNA large subunit methyltransferase J

342

0.585

2454

0.912

477

0.438

0

ACIAD2418

prfA

peptide chain release factor 1

573

0.514

358

0.973

478

0.438

0

ACIAD0875

thiD

bifunctional protein [Includes: hydroxy-methylpyrimidine kinase (HMP kinase); hydroxy-phosphomethylpyrimidine kinase (HMP-P kinase)]

2.7.4.7

577

0.514

358

0.973

479

0.438

0

ACIAD3245

putative ATP-dependent RNA helicase

695

0.487

1

1.000

480

0.438

0

ACIAD3469

putative two-component response regulator

402

0.566

1423

0.927

481

0.438

0

ACIAD2518

pxpC

putative L-5-oxoprolinase (ATP-dependent) subunit C

3.5.2.9

534

0.528

825

0.960

482

0.437

0

ACIAD0039

argA

N-alpha-acetylglutamate synthase (amino-acid acetyltransferase)

2.3.1.1

407

0.565

1423

0.927

483

0.437

0

ACIAD3399

putative peptide synthetase

455

0.549

1052

0.940

484

0.437

0

ACIAD3447

putative transcriptional regulator (GntR family)

450

0.551

1189

0.939

485

0.437

0

ACIAD1045

metH

methionine synthase (B12-dependent homocysteine-N5-methyltetrahydrofolate transmethylase, repressor of metE and metF)

2.1.1.13

408

0.564

1423

0.927

486

0.436

0

ACIAD0839

ffh

4.5S-RNP protein, GTP binding export factor, part of signal recognition particle with 4.5 RNA

588

0.512

358

0.973

487

0.436

0

ACIAD0744

upp

uracil phosphoribosyltransferase

2.4.2.9

586

0.512

358

0.973

488

0.436

0

ACIAD2386

rih

ribonucleoside hydrolase

3.2.2.-

708

0.484

1

1.000

489

0.435

0

ACIAD1201

hemL

glutamate-1-semialdehyde aminotransferase

5.4.3.8

463

0.547

1189

0.939

490

0.435

0

ACIAD3389

envZ

sensory histidine kinase in two-component regulatory system with OmpR

539

0.524

825

0.960

491

0.435

0

ACIAD2392

rbsK

ribokinase

2.7.1.15

599

0.509

358

0.973

492

0.434

0

ACIAD2367

soj

chromosome partitioning protein

593

0.511

733

0.972

493

0.434

0

ACIAD2314

metZ

o-acylhomoserine sulfhydrylase

2.5.1.-

715

0.482

1

1.000

494

0.434

0

ACIAD1659

putative transcriptional regulator (LysR family); putative glycine cleavage system transcriptional activator (Gcv operon activator)(GcvA)

187

0.651

3154

0.861

495

0.434

0

ACIAD0380

hisIE

bifunctional protein [Includes: phosphoribosyl-AMP cyclohydrolase; phosphoribosyl-ATP pyrophosphatase]

3.5.4.19, 3.6.1.31

434

0.556

1370

0.931

496

0.434

0

ACIAD0297

trpE

anthranilate synthase component I

4.1.3.27

716

0.482

1

1.000

497

0.434

0

ACIAD3341

putative arginine/lysine/ornithine decarboxylase

4.1.1.-

416

0.562

1423

0.927

498

0.434

0

ACIAD3557

phoB

positive response regulator for the pho regulon, autophosphorylates and phosphorylates sensor PhoR

406

0.565

1921

0.924

499

0.434

0

ACIAD2408

folB

dihydroneopterin aldolase

4.1.2.25

474

0.544

1052

0.940

500

0.433

0

ACIAD1219

purB

adenylosuccinate lyase

4.3.2.2

600

0.508

358

0.973

501

0.433

0

PhyloProfile Search: ACIAD2729