BLASTP 2.12.0+


Reference: Stephen F. Altschul, Thomas L. Madden, Alejandro A.
Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J.
Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of
protein database search programs", Nucleic Acids Res. 25:3389-3402.


Reference for composition-based statistics: Alejandro A. Schaffer,
L. Aravind, Thomas L. Madden, Sergei Shavirin, John L. Spouge, Yuri
I. Wolf, Eugene V. Koonin, and Stephen F. Altschul (2001),
"Improving the accuracy of PSI-BLAST protein database searches with
composition-based statistics and other refinements", Nucleic Acids
Res. 29:2994-3005.



Database: c8408770500f670db1e9eaad0fff98c8.SwissProt.fasta
           19 sequences; 6,641 total letters



Query= Z4808

Length=346
                                                                      Score     E
Sequences producing significant alignments:                          (Bits)  Value

P46853 Uncharacterized oxidoreductase YhhX [Escherichia coli (str...  699     0.0  
P77376 Uncharacterized oxidoreductase YdgJ [Escherichia coli (str...  199     2e-64
O13991 Uncharacterized oxidoreductase C26H5.09c [Schizosaccharomy...  191     6e-61
O42896 Uncharacterized oxidoreductase C115.03 [Schizosaccharomyce...  185     9e-59
O32223 scyllo-inositol 2-dehydrogenase (NADP(+)) IolW [Bacillus s...  174     7e-55
Q04869 Uncharacterized protein YMR315W [Saccharomyces cerevisiae ...  78.2    2e-19
P74041 Uncharacterized oxidoreductase sll0816 [Synechocystis sp. ...  70.1    1e-16
T2KNC8 Oxidoreductase P35 [Formosa agariphila (strain DSM 15362 /...  66.2    2e-15
O68965 Inositol 2-dehydrogenase [Rhizobium meliloti (strain 1021)]    63.9    1e-14
Q8GAK6 D-xylose dehydrogenase [Paenarthrobacter nicotinovorans]       63.9    1e-14
P40332 scyllo-inositol 2-dehydrogenase (NAD(+)) [Bacillus subtili...  63.2    2e-14
A0A024SMV2 D-xylose 1-dehydrogenase (NADP(+)) [Hypocrea jecorina ...  62.0    6e-14
Q9WYP5 Myo-inositol 2-dehydrogenase [Thermotoga maritima (strain ...  58.5    7e-13
P53004 Biliverdin reductase A [Homo sapiens]                          58.2    8e-13
Q2I8V6 1,5-anhydro-D-fructose reductase [Ensifer adhaerens]           57.8    1e-12
Q44258 1-carboxy-3-chloro-3,4-dihydroxycyclo hexa-1,5-diene dehyd...  57.8    2e-12
Q9TV68 Trans-1,2-dihydrobenzene-1,2-diol dehydrogenase [Canis lup...  55.1    1e-11
Q7JK39 Trans-1,2-dihydrobenzene-1,2-diol dehydrogenase [Macaca fu...  54.3    2e-11
Q9TQS6 Trans-1,2-dihydrobenzene-1,2-diol dehydrogenase [Macaca fa...  54.3    2e-11


>P46853 Uncharacterized oxidoreductase YhhX [Escherichia coli 
(strain K12)]
Length=345

 Score = 699 bits (1804),  Expect = 0.0
 Identities = 343/345 (99%), Positives = 345/345 (100%), Gaps = 0/345 (0%)

Query  1    MVINCAFIGFGKSTTRYHLPYVLNRKDSWHVAHIFRRHAKPEEQAPIYSHIHFTSDLNEV  60
            MVINCAFIGFGKSTTRYHLPYVLNRKDSWHVAHIFRRHAKPEEQAPIYSHIHFTSDL+EV
Sbjct  1    MVINCAFIGFGKSTTRYHLPYVLNRKDSWHVAHIFRRHAKPEEQAPIYSHIHFTSDLDEV  60

Query  61   LNDPDVKLVVVCTHADSHFEYAKRAMEAGKNVLVEKPFTPTLAQAKELFALAKSKGLTVT  120
            LNDPDVKLVVVCTHADSHFEYAKRA+EAGKNVLVEKPFTPTLAQAKELFALAKSKGLTVT
Sbjct  61   LNDPDVKLVVVCTHADSHFEYAKRALEAGKNVLVEKPFTPTLAQAKELFALAKSKGLTVT  120

Query  121  PYQNRRFDSCFLTAKKAIESGKLGEIVEVESHFDYYRPVAETKPGLPQDGAFYGLGVHTM  180
            PYQNRRFDSCFLTAKKAIESGKLGEIVEVESHFDYYRPVAETKPGLPQDGAFYGLGVHTM
Sbjct  121  PYQNRRFDSCFLTAKKAIESGKLGEIVEVESHFDYYRPVAETKPGLPQDGAFYGLGVHTM  180

Query  181  DQIISLFGRPDHVAYDIRSLRNKANPDDTFEAQLFYGDLKAIVKTSHLVKIDYPKFIVHG  240
            DQIISLFGRPDHVAYDIRSLRNKANPDDTFEAQLFYGDLKAIVKTSHLVKIDYPKFIVHG
Sbjct  181  DQIISLFGRPDHVAYDIRSLRNKANPDDTFEAQLFYGDLKAIVKTSHLVKIDYPKFIVHG  240

Query  241  KKGSFIKYGIDQQETSLKANIMPGEPGFAADDSVGVLEYVNDEGVTVREEMKPEMGDYGR  300
            KKGSFIKYGIDQQETSLKANIMPGEPGFAADDSVGVLEYVNDEGVTVREEMKPEMGDYGR
Sbjct  241  KKGSFIKYGIDQQETSLKANIMPGEPGFAADDSVGVLEYVNDEGVTVREEMKPEMGDYGR  300

Query  301  VYDALYQTITHGAPNYVKESEVLTNLEILERGFEQASPSTVTLAK  345
            VYDALYQTITHGAPNYVKESEVLTNLEILERGFEQASPSTVTLAK
Sbjct  301  VYDALYQTITHGAPNYVKESEVLTNLEILERGFEQASPSTVTLAK  345


>P77376 Uncharacterized oxidoreductase YdgJ [Escherichia coli 
(strain K12)]
Length=346

 Score = 199 bits (506),  Expect = 2e-64
 Identities = 121/337 (36%), Positives = 176/337 (52%), Gaps = 7/337 (2%)

Query  3    INCAFIGFGKSTTRYHLPYVLNRKDSWHVAHIFRRHAKPEEQAPIYSHIHFTSDLNEVLN  62
            I    IG+G ++  +H P +                 K +   P  + +   S+   + N
Sbjct  5    IRVGLIGYGYASKTFHAPLIAGTPGQELAVISSSDETKVKADWPTVTVV---SEPKHLFN  61

Query  63   DPDVKLVVVCTHADSHFEYAKRAMEAGKNVLVEKPFTPTLAQAKELFALAKSKGLTVTPY  122
            DP++ L+V+ T  D+HF  AK A+EAGK+V+V+KPFT TL+QA+EL ALAKS G  ++ +
Sbjct  62   DPNIDLIVIPTPNDTHFPLAKAALEAGKHVVVDKPFTVTLSQARELDALAKSLGRVLSVF  121

Query  123  QNRRFDSCFLTAKKAIESGKLGEIVEVESHFDYYRPVAETK---PGLPQDGAFYGLGVHT  179
             NRR+DS FLT K  +  G LGE+   ESHFD +RP    +    G P  G +Y L  H 
Sbjct  122  HNRRWDSDFLTLKGLLAEGVLGEVAYFESHFDRFRPQVRDRWREQGGPGSGIWYDLAPHL  181

Query  180  MDQIISLFGRPDHVAYDIRSLRNKANPDDTFEAQLFYGDLKAIVKTSHLVKIDYPKFIVH  239
            +DQ I+LFG P  +  D+  LR  A   D F A L Y   + I+  + L   +  ++IVH
Sbjct  182  LDQAITLFGLPVSMTVDLAQLRPGAQSTDYFHAILSYPQRRVILHGTMLAAAESARYIVH  241

Query  240  GKKGSFIKYGIDQQETSLKANIMPGEPGFAADDSVGVLEYVNDEGVTVREEMKPEMGDYG  299
            G +GS++KYG+D QE  LK      +  +  D   GVL  V  E   V E +    G+Y 
Sbjct  242  GSRGSYVKYGLDPQEERLKNGERLPQEDWGYDMRDGVLTRVEGE-ERVEETLLTVPGNYP  300

Query  300  RVYDALYQTITHGAPNYVKESEVLTNLEILERGFEQA  336
              Y A+   +     N V  S+ +  +E++E G E A
Sbjct  301  AYYAAIRDALNGDGENPVPASQAIQVMELIELGIESA  337


>O13991 Uncharacterized oxidoreductase C26H5.09c [Schizosaccharomyces 
pombe (strain 972 / ATCC 24843)]
Length=369

 Score = 191 bits (484),  Expect = 6e-61
 Identities = 129/361 (36%), Positives = 188/361 (52%), Gaps = 24/361 (7%)

Query  3    INCAFIGFGKSTTRYHLPYVLNRKDSWHVAHIFRRHAKPEEQAP--IYSHIHFTSDLNEV  60
            I  A +G G S   +H P++    + + V   + R A   E      + ++   + L+E+
Sbjct  4    IKTAVLGTGMSAFIFHYPFLKALPNHFEVYAAWERRATSTESKARAAFPNVKVYTKLDEL  63

Query  61   LNDPDVKLVVVCTHADSHFEYAKRAMEAGKNVLVEKPFTPTLAQAKELFALAKSKGLTVT  120
            L D +++LVV+    + H+E   +A+ AGK+VL EKPFTPT  +AKELF LAKSK L +T
Sbjct  64   LADSNIELVVISLPPNVHYEVVSQALNAGKHVLCEKPFTPTYGEAKELFDLAKSKNLMLT  123

Query  121  PYQNRRFDSCFLTAKKAIESGKLGEIVEVESHFDYYRPVAETK----PGLPQDGAFYGLG  176
             YQNRRFD  FLTAK+ IE+G+LGE+V+ ESH D +R   +      P  P  G  Y LG
Sbjct  124  VYQNRRFDGDFLTAKECIENGRLGEVVQFESHIDRFRLFRKGNWKDVPN-PGCGLVYDLG  182

Query  177  VHTMDQIISLFGRPDHVAYDIRSLRN--KANPDDTFEAQLFY------GDLKAIVKTSHL  228
             H +DQ I+LFG P  V   + S R       +D F   L Y        L  IV +S +
Sbjct  183  SHLIDQAITLFGTPHSVTAKLESQRQIPPLEVEDCFRIVLHYLPQEGRLPLDVIVCSSSI  242

Query  229  VKIDYPKFIVHGKKGSFIKYGIDQQETSLKANIMPGEPGFAADDSVGVLE-YVNDEGVTV  287
                  ++I+ G +GSF+K+GID QE+ L   + P +PG+  D S      +     + V
Sbjct  243  SCGLDMRYIIKGTRGSFLKFGIDPQESQLNEGMSPMDPGYGVDSSHHYATLWTLPPDIDV  302

Query  288  REEMKPE-------MGDYGRVYDALYQT-ITHGAPNYVKESEVLTNLEILERGFEQASPS  339
            R   KP         GDY R Y  +++  +T      VK  +VL   +I+E  ++ +  S
Sbjct  303  RHPPKPTKSTLMTIAGDYRRFYLEVHEALVTKTFETSVKPHQVLLVEKIIEAAYKSSQSS  362

Query  340  T  340
            T
Sbjct  363  T  363


>O42896 Uncharacterized oxidoreductase C115.03 [Schizosaccharomyces 
pombe (strain 972 / ATCC 24843)]
Length=368

 Score = 185 bits (469),  Expect = 9e-59
 Identities = 126/364 (35%), Positives = 192/364 (53%), Gaps = 29/364 (8%)

Query  3    INCAFIGFGKSTTRYHLPYVLNRKDSWHVAHIFRRHAKPEEQAP--IYSHIHFTSDLNEV  60
            I  A +G G S   +H P++      + +     R A   +      Y +I   ++L+E+
Sbjct  4    IKTAVLGTGVSAFVFHFPFLEALPSKFEIYACLERRATVTQSKARSAYPNILVYTNLDEL  63

Query  61   LNDPDVKLVVVCTHADSHFEYAKRAMEAGKNVLVEKPFTPTLAQAKELFALAKSKGLTVT  120
            L D +++LVVV    + H E  K+A+ AGK+V+ EKPFTPT  +AKEL+ LA+SK L + 
Sbjct  64   LADVNIELVVVSLPPNVHSEIVKKALNAGKHVVCEKPFTPTYEEAKELYELAESKSLLLA  123

Query  121  PYQNRRFDSCFLTAKKAIESGKLGEIVEVESHFDYYRP-------VAETKPGLPQDGAFY  173
             YQNRR+D  FLTAKK IESG+LG++VE ESHFD YR          E +PG   +G  Y
Sbjct  124  IYQNRRWDGDFLTAKKIIESGRLGQVVEFESHFDRYRLGRKSGSWKDEPRPG---NGMVY  180

Query  174  GLGVHTMDQIISLFGRPDHVAYDIRSLRN--KANPDDTFEAQLFYG------DLKAIVKT  225
            G+G H +DQ +SLFG P  V   + + R       +D F   L Y        +  I+ +
Sbjct  181  GIGSHLIDQAVSLFGTPYSVTAKLEAQRQIPPLEVEDYFRIILHYPAKGNKLPINVILSS  240

Query  226  SHLVKIDYPKFIVHGKKGSFIKYGIDQQETSLKANIMPGEPGFAAD--DSVGVLEYVN-D  282
            +++      +F + G +GSF+K+G D QE+ L + + P + GF  D  +  G L  V  D
Sbjct  241  TNVSCGCEMRFCIKGTRGSFMKFGFDPQESQLHSGMKPNDHGFGTDRFELYGNLWTVPLD  300

Query  283  EGVTVREE-----MKPEMGDYGRVYDALYQTITHGAPNY-VKESEVLTNLEILERGFEQA  336
              V    E     +    G+Y   YDA+++ I   A  + +K  +VL   +I+E  ++ +
Sbjct  301  ADVKALPEPTKITVPTVQGNYRDFYDAVFEEILKKANEFPIKSDQVLAVEKIMEAAYKSS  360

Query  337  SPST  340
              S+
Sbjct  361  ESSS  364


>O32223 scyllo-inositol 2-dehydrogenase (NADP(+)) IolW [Bacillus 
subtilis (strain 168)]
Length=358

 Score = 174 bits (442),  Expect = 7e-55
 Identities = 110/339 (32%), Positives = 173/339 (51%), Gaps = 9/339 (3%)

Query  3    INCAFIGFGKSTTRYHLPYVLNRKDSWHVAHIFRRHAKPEEQAPIYSHIHFTSDLNEVLN  62
            I    +G+G S + +H P +L+  D + ++ I    ++ EE    +       +L E+ N
Sbjct  14   IKVGILGYGLSGSVFHGP-LLDVLDEYQISKIMT--SRTEEVKRDFPDAEVVHELEEITN  70

Query  63   DPDVKLVVVCTHADSHFEYAKRAMEAGKNVLVEKPFTPTLAQAKELFALAKSKGLTVTPY  122
            DP ++LV+V T +  H+E+    ++AGK+V++EKP T T  + + L   A  KG+ ++ Y
Sbjct  71   DPAIELVIVTTPSGLHYEHTMACIQAGKHVVMEKPMTATAEEGETLKRAADEKGVLLSVY  130

Query  123  QNRRFDSCFLTAKKAIESGKLGEIVEVESHFDYYRPVAET----KPGLPQDGAFYGLGVH  178
             NRR+D+ FLT KK I  G L +I   +  ++ YRP  +     K G    G  Y LG H
Sbjct  131  HNRRWDNDFLTIKKLISEGSLEDINTYQVSYNRYRPEVQARWREKEG-TATGTLYDLGSH  189

Query  179  TMDQIISLFGRPDHVAYDIRSLRNKANPDDTFEAQLFYGDLKAIVKTSHLVKIDYPKFIV  238
             +DQ + LFG P  V  ++ + R  A   D F   L YG L+AI+    +V  + P++ +
Sbjct  190  IIDQTLHLFGMPKAVTANVMAQRENAETVDYFHLTLDYGKLQAILYGGSIVPANGPRYQI  249

Query  239  HGKKGSFIKYGIDQQETSLKANIMPGEPGFAADDSVGVLEYVNDEGVTVREEMKPEM-GD  297
            HGK  SFIKYGID QE +L+A   P +  + AD      +     G   + E  P + G 
Sbjct  250  HGKDSSFIKYGIDGQEDALRAGRKPEDDSWGADVPEFYGKLTTIRGSDKKTETIPSVNGS  309

Query  298  YGRVYDALYQTITHGAPNYVKESEVLTNLEILERGFEQA  336
            Y   Y  + ++I  GA   V   E +  + I+E   E +
Sbjct  310  YLTYYRKIAESIREGAALPVTAEEGINVIRIIEAAMESS  348


>Q04869 Uncharacterized protein YMR315W [Saccharomyces cerevisiae 
(strain ATCC 204508 / S288c)]
Length=349

 Score = 78.2 bits (191),  Expect = 2e-19
 Identities = 85/316 (27%), Positives = 131/316 (41%), Gaps = 47/316 (15%)

Query  3    INCAFIGFGKSTTRYHLPYVLNRKDSWHVAHIFRRH-AKPEEQAPIYS--HIHFTSDLNE  59
            +N   +G G      HLP      D + V   F RH AK  + A +          +L+E
Sbjct  4    LNVGIVGTGIFARDRHLPSYQEFPDKFKVIAAFNRHKAKALDFAKVADIPENKVYDNLDE  63

Query  60   VLNDPDVKLVVVCTHADSHFEYAKRAMEAGKNVLVEKPFTPTLAQAKELFALAKSKGLTV  119
            +LNDP V  +     A  + +  ++A++AGK V++EKP    L QAKE+  +A+S  L V
Sbjct  64   ILNDPHVDYIDALLPAQFNADIVEKAVKAGKPVILEKPIAANLDQAKEIVKIAESTPLPV  123

Query  120  TPYQNRRFDSCFLTAKKAIESGKLGEIVEVE--------SHFDYYRPVAETKP----GLP  167
               +N  +  C   AK+ IE  K+G +V           +   Y       KP    G  
Sbjct  124  GVAENWLYLPCIKIAKEQIE--KIGPVVAFTHNSTGPFVTQNKYLTTTWRQKPEHIGGFL  181

Query  168  QDGAFYGLGVHTMDQIISLFGRPDHVAYDIRSLRNKANPDDTFEA-----------QLFY  216
             DG     GVH +  +ISL G    V+   R +R ++  DD   A              Y
Sbjct  182  SDG-----GVHQLALVISLLGEFGSVSALTRQVRERSGADDIVFATVQLKNKEVIGSFTY  236

Query  217  GDLKAIVKTSHLVKIDYPKFIVHGKKGSFIKYGIDQQETSLKANIMPGEPGFAADDS--V  274
            G      + S  +K       V+GK G+      D+++  +K  +     G +A+D+   
Sbjct  237  GSAFGATEKSVFLK-------VYGKNGTVTVDLSDKKDPVVKVKL-----GGSAEDNGDE  284

Query  275  GVLEYVNDEGVTVREE  290
             + +  NDE   V  E
Sbjct  285  QIFKVDNDESFGVNAE  300


>P74041 Uncharacterized oxidoreductase sll0816 [Synechocystis 
sp. (strain PCC 6803 / Kazusa)]
Length=371

 Score = 70.1 bits (170),  Expect = 1e-16
 Identities = 65/257 (25%), Positives = 122/257 (47%), Gaps = 24/257 (9%)

Query  9    GFGKSTTRYHLPYVLNRKDSWHVAHIFRRHAKPEEQAPIYSHIHFTSDLNEVLNDPDVKL  68
            GFG++    H+P +   + +  +A   R  AK +E A      +  ++L E+L +P+V+ 
Sbjct  15   GFGQAV---HIPALQYHQQTQAIAIYHRDLAKAQEVAKSNDLAYSYNNLEELLANPEVQA  71

Query  69   VVVCTHADSHFEYAKRAMEAGKNVLVEKPFTPTLAQAKELFALAKSKGLTVTPYQNRRFD  128
            V + +    H+E AK+A+ AGK+VL+EKP T  + +  EL+ LA+ + + V P    RF 
Sbjct  72   VTIASPPFLHYEMAKQAILAGKHVLLEKPMTLRVEETIELYHLARQREVQVIPDFEFRFV  131

Query  129  SCFLTAKKAIESGKLGEIVEVESHF---------DYYRPVAETKPGLPQDGAFYGLGVHT  179
              +    + +  G LG++  ++  +           +   A+ + G    GA   L  HT
Sbjct  132  PAWQYVAELLGQGILGQLKLIKVDWLVGSRANPNRAWNWYAQREKG---GGALGALASHT  188

Query  180  MDQIISLFGRPDHVAYDIR-SLRNKANPDDTFEAQLFYGDLKAIVKTSHLVKIDYP----  234
             D +  LFG    +A ++  ++  + +P D    +    +  A++  S  +  D P    
Sbjct  189  FDYLHWLFGPAQSLAANLSVAIAERPDPLDNNRLKPVTAEDTALI--SLTLANDVPCQIN  246

Query  235  -KFIVHGKKGSFIK-YG  249
               + HG +G +++ YG
Sbjct  247  ITSVAHGGRGHWLEIYG  263


>T2KNC8 Oxidoreductase P35 [Formosa agariphila (strain DSM 15362 
/ KCTC 12365 / LMG 23005 / KMM 3901 / M-2Alg 35-1)]
Length=321

 Score = 66.2 bits (160),  Expect = 2e-15
 Identities = 50/200 (25%), Positives = 87/200 (44%), Gaps = 9/200 (5%)

Query  3    INCAFIGFGKSTTRYHLPYVLNRKDSWHVAHIFRRHAKPEEQAPIYSHIHFTSDLNEVLN  62
            IN   IG G        P     ++S  VA + R   K  + A  +   ++T++   ++ 
Sbjct  5    INWGIIGCGNVAEVKSGPAFYKTENSTLVAVMRRNEDKVIDFANRHGVANWTTNAEALIQ  64

Query  63   DPDVKLVVVCTHADSHFEYAKRAMEAGKNVLVEKPFTPTLAQAKELFALAKSKGLTVTPY  122
            +  +  V + T   SH +YA RA+  GKNV +EKP      +A  L    K   + VT  
Sbjct  65   NDLINAVYIATPPSSHLQYALRAINVGKNVYLEKPMVLNNHEANILVEAVKRSNVKVTVA  124

Query  123  QNRRFDSCFLTAKKAIESGKLGEIVEVESHFDYYRP---VAETK------PGLPQDGAFY  173
              RR    +L  K+ ++S  +G ++  E      R    +A+T+      P +   G F+
Sbjct  125  HYRRELPVYLKIKELLDSNVIGNVISAEIQIKQTRNTNLIAKTEVNWRTIPEISGGGYFH  184

Query  174  GLGVHTMDQIISLFGRPDHV  193
             +  H +D +   FG  +++
Sbjct  185  DIAPHQIDLMCHYFGEVENI  204


 Score = 19.2 bits (38),  Expect = 2.8
 Identities = 7/30 (23%), Positives = 14/30 (47%), Gaps = 0/30 (0%)

Query  311  HGAPNYVKESEVLTNLEILERGFEQASPST  340
            HG  N+   +E L   +++   +    PS+
Sbjct  50   HGVANWTTNAEALIQNDLINAVYIATPPSS  79


>O68965 Inositol 2-dehydrogenase [Rhizobium meliloti (strain 1021)]
Length=330

 Score = 63.9 bits (154),  Expect = 1e-14
 Identities = 72/253 (28%), Positives = 100/253 (40%), Gaps = 15/253 (6%)

Query  1    MVINCAFIGFGKSTTRYHLPYVLNRKDSWHVAHIFRRHAKPEEQAPIYSHIHFTSDLNEV  60
            M +    +G G+   + H   V    D+  VA      A  E  A  Y     T D  E 
Sbjct  1    MTVRFGLLGAGR-IGKVHAKAVSGNADARLVAVADAFPAAAEAIAGAYGCEVRTIDAIEA  59

Query  61   LNDPDVKLVVVCTHADSHFEYAKRAMEAGKNVLVEKPFTPTLAQAKELFALAKSKGLTVT  120
              D D   VV+CT  D+H +  +R   AGK +  EKP      + +    +       + 
Sbjct  60   AADIDA--VVICTPTDTHADLIERFARAGKAIFCEKPIDLDAERVRACLKVVSDTKAKLM  117

Query  121  PYQNRRFDSCFLTAKKAIESGKLGEI--VEVESHFDYYRPVAETKPGLPQDGAFYGLGVH  178
               NRRFD  F+  +KAI+ G++GE+  V + S      PV   K      G F  + +H
Sbjct  118  VGFNRRFDPHFMAVRKAIDDGRIGEVEMVTITSRDPSAPPVDYIK---RSGGIFRDMTIH  174

Query  179  TMDQIISLFG-RPDHVAYDIRSLRNKANPD----DTFEAQLFYGDLK-AIVKTSHLVKID  232
              D    L G  P  V      L +KA  D    D+    L     K AI+  S      
Sbjct  175  DFDMARFLLGEEPVSVTATAAVLIDKAIGDAGDYDSVSVILQTASGKQAIISNSRRATYG  234

Query  233  YPKFI-VHGKKGS  244
            Y + I VHG KG+
Sbjct  235  YDQRIEVHGSKGA  247


>Q8GAK6 D-xylose dehydrogenase [Paenarthrobacter nicotinovorans]
Length=388

 Score = 63.9 bits (154),  Expect = 1e-14
 Identities = 34/121 (28%), Positives = 60/121 (50%), Gaps = 0/121 (0%)

Query  36   RRHAKPEEQAPIYSHIHFTSDLNEVLNDPDVKLVVVCTHADSHFEYAKRAMEAGKNVLVE  95
            R  AK  E A  +    +++DL+ V+NDP V ++   +         K+AM AGK++  E
Sbjct  54   RNEAKIRELAEKHKVAEWSTDLDSVVNDPTVDIIFDASMTSLRAATLKKAMLAGKHIFTE  113

Query  96   KPFTPTLAQAKELFALAKSKGLTVTPYQNRRFDSCFLTAKKAIESGKLGEIVEVESHFDY  155
            KP   TL +A EL  + K  G+T     ++ +    +  ++ ++ G  G I+ +   F Y
Sbjct  114  KPTAETLEEAIELARIGKQAGVTAGVVHDKLYLPGLVKLRRLVDEGFFGRILSIRGEFGY  173

Query  156  Y  156
            +
Sbjct  174  W  174


>P40332 scyllo-inositol 2-dehydrogenase (NAD(+)) [Bacillus subtilis 
(strain 168)]
Length=342

 Score = 63.2 bits (152),  Expect = 2e-14
 Identities = 40/142 (28%), Positives = 65/142 (46%), Gaps = 13/142 (9%)

Query  53   FTSDLNEVLNDPDVKLVVVCTHADSHFEYAKRAMEAGKNVLVEKPFTPTLAQAKELFALA  112
            ++ D  EVL DP +  V++ T   +H +   +A E GK + VEKP T +L ++K      
Sbjct  55   WSEDPYEVLEDPGIDAVIIVTPTSTHGDMIIKAAENGKQIFVEKPLTLSLEESKAASEKV  114

Query  113  KSKGLTVTPYQNRRFDSCFLTAKKAIESGKLGEIVEVESHFDYYRPVAETKPGLPQD---  169
            K  G+       RRFD  +  AK+ I++G++G+ +       YY+     +   P +   
Sbjct  115  KETGVICQVGFMRRFDPAYADAKRRIDAGEIGKPI-------YYKGFTRDQGAPPAEFIK  167

Query  170  ---GAFYGLGVHTMDQIISLFG  188
               G F    +H  D    L G
Sbjct  168  HSGGIFIDCSIHDYDIARYLLG  189


>A0A024SMV2 D-xylose 1-dehydrogenase (NADP(+)) [Hypocrea jecorina 
(strain ATCC 56765 / BCRC 32924 / NRRL 11460 / Rut C-30)]
Length=391

 Score = 62.0 bits (149),  Expect = 6e-14
 Identities = 34/88 (39%), Positives = 52/88 (59%), Gaps = 0/88 (0%)

Query  59   EVLNDPDVKLVVVCTHADSHFEYAKRAMEAGKNVLVEKPFTPTLAQAKELFALAKSKGLT  118
            E++ DP+V +V V T    HF+    A+EAGKNVL EK FT T AQA++L   AK+K L 
Sbjct  76   ELVADPNVDIVYVATPHSHHFQNTMLALEAGKNVLCEKAFTVTAAQARKLVETAKAKKLF  135

Query  119  VTPYQNRRFDSCFLTAKKAIESGKLGEI  146
            +      R+    +  ++ I +G++G +
Sbjct  136  LMEAVWTRYFPLSIKIRELIAAGEIGTV  163


>Q9WYP5 Myo-inositol 2-dehydrogenase [Thermotoga maritima (strain 
ATCC 43589 / DSM 3109 / JCM 10099 / NBRC 100826 / MSB8)]
Length=334

 Score = 58.5 bits (140),  Expect = 7e-13
 Identities = 39/141 (28%), Positives = 64/141 (45%), Gaps = 17/141 (12%)

Query  56   DLNEVLNDPDVKLVVVCTHADSHFEYAKRAMEAGKNVLVEKPFTPTLAQAKELFALAKSK  115
            D +E++ DP+V  V+VC+  ++H E      +A K+V  EKP +  LA    +    K  
Sbjct  53   DPHELIEDPNVDAVLVCSSTNTHSELVIACAKAKKHVFCEKPLSLNLADVDRMIEETKKA  112

Query  116  GLTVTPYQNRRFDSCFLTAKKAIESGKLGE--IVEVESH------FDYYRPVAETKPGLP  167
             + +    NRRFD  F   K+A+E+G +G+  ++ + S        DY R          
Sbjct  113  DVILFTGFNRRFDRNFKKLKEAVENGTIGKPHVLRITSRDPAPPPLDYIR---------V  163

Query  168  QDGAFYGLGVHTMDQIISLFG  188
              G F  + +H  D    + G
Sbjct  164  SGGIFLDMTIHDFDMARYIMG  184


>P53004 Biliverdin reductase A [Homo sapiens]
Length=296

 Score = 58.2 bits (139),  Expect = 8e-13
 Identities = 41/132 (31%), Positives = 69/132 (52%), Gaps = 9/132 (7%)

Query  57   LNEVLNDPDVKLVVVCTHADSHFEYAKRAMEAGKNVLVEKPFTPTLAQAKELFALAKSKG  116
            L + L+  +V++  +C+ + SH +Y ++ + AGK+VLVE P T +LA A+EL+ LA+ KG
Sbjct  59   LEDALSSQEVEVAYICSESSSHEDYIRQFLNAGKHVLVEYPMTLSLAAAQELWELAEQKG  118

Query  117  LTVTPYQNRRFDSCFLTAKKAIESGKLGEIVEVESHFDYYRPVAETKPGLPQDGAFYGLG  176
              +           F   KK +    +G+ +   S      P+ E + G P   AF   G
Sbjct  119  KVLHEEHVELLMEEFAFLKKEV----VGKDLLKGSLLFTAGPLEEERFGFP---AF--SG  169

Query  177  VHTMDQIISLFG  188
            +  +  ++SLFG
Sbjct  170  ISRLTWLVSLFG  181


>Q2I8V6 1,5-anhydro-D-fructose reductase [Ensifer adhaerens]
Length=333

 Score = 57.8 bits (138),  Expect = 1e-12
 Identities = 51/207 (25%), Positives = 82/207 (40%), Gaps = 7/207 (3%)

Query  55   SDLNEVLNDPDVKLVVVCTHADSHFEYAKRAMEAGKNVLVEKPFTPTLAQAKELFALAKS  114
            + + E++ DPDV  V V T  + H E    A+ AGK+VL EKP   TL  A+E+   A+ 
Sbjct  53   TSVEELVGDPDVDAVYVSTTNELHREQTLAAIRAGKHVLCEKPLAMTLEDAREMVVAARE  112

Query  115  KGLTVTPYQNRRFDSCFLTAKKAIESGKLGEIVEVESHFDYYRP--VAETKPGLPQ--DG  170
             G+ +    + R  +     + AI  G++G  +        Y P  +   +   P+   G
Sbjct  113  AGVVLGTNHHLRNAAAHRAMRDAIAEGRIGRPIAARVFHAVYLPPHLQGWRLERPEAGGG  172

Query  171  AFYGLGVHTMDQIISLFGRPDHVAYDI---RSLRNKANPDDTFEAQLFYGDLKAIVKTSH  227
                + VH  D +  +       A  I     +  +   D       F   + A    + 
Sbjct  173  VILDITVHDADTLRFVLNDDPAEAVAISHSAGMGKEGVEDGVMGGVRFQSGVIAQFHDAF  232

Query  228  LVKIDYPKFIVHGKKGSFIKYGIDQQE  254
              K     F VHG +GS I   +  Q+
Sbjct  233  TTKFAETGFEVHGTEGSLIGRNVMTQK  259


 Score = 18.9 bits (37),  Expect = 3.7
 Identities = 9/19 (47%), Positives = 13/19 (68%), Gaps = 1/19 (5%)

Query  89   GKNVLVEKPF-TPTLAQAK  106
            G+NV+ +KP  T TL  A+
Sbjct  252  GRNVMTQKPVGTVTLRNAE  270


>Q44258 1-carboxy-3-chloro-3,4-dihydroxycyclo hexa-1,5-diene dehydrogenase 
[Comamonas testosteroni]
Length=397

 Score = 57.8 bits (138),  Expect = 2e-12
 Identities = 36/106 (34%), Positives = 57/106 (54%), Gaps = 3/106 (3%)

Query  56   DLNEVLNDPDVKLVVVCTHADSHFEYAKRAMEAGKNVLVEKPFTPTLAQAKELFALAKSK  115
            D+  +  +PDV++V + T    H  +A+ A+ AGK+VLVEKP   TL     + A A+  
Sbjct  53   DIESLCKNPDVEVVYIGTPHQFHAVHAEIALNAGKHVLVEKPMAVTLEDCCRMNACAQRA  112

Query  116  GLTVTPYQNRRFDSCFLTAKKAIESGKLGEIVEVES--HFDY-YRP  158
            G  +    +  FD     AK+ I+SG+ G +  + S  + D+ YRP
Sbjct  113  GKYLIVGHSHSFDHPISRAKELIDSGRYGRVRFIHSMNYTDFLYRP  158


 Score = 18.5 bits (36),  Expect = 5.0
 Identities = 8/18 (44%), Positives = 9/18 (50%), Gaps = 0/18 (0%)

Query  230  KIDYPKFIVHGKKGSFIK  247
            K D+P   VHG   S  K
Sbjct  42   KADFPAAAVHGDIESLCK  59


>Q9TV68 Trans-1,2-dihydrobenzene-1,2-diol dehydrogenase [Canis 
lupus familiaris]
Length=335

 Score = 55.1 bits (131),  Expect = 1e-11
 Identities = 41/159 (26%), Positives = 65/159 (41%), Gaps = 1/159 (1%)

Query  59   EVLNDPDVKLVVVCTHADSHFEYAKRAMEAGKNVLVEKPFTPTLAQAKELFALAKSKGLT  118
            E+  DP+V++  + T    H       + AGK VL EKP     A+ +E+ A A+S+GL 
Sbjct  60   ELAKDPNVEVAYIGTQHPQHKAAVLLCLAAGKAVLCEKPMGVNAAEVREMVAEARSRGLF  119

Query  119  VTPYQNRRFDSCFLTAKKAIESGKLGEIVEVESHF-DYYRPVAETKPGLPQDGAFYGLGV  177
            +      RF       + A+  G LGE+    + F   +  +  +       G    LG+
Sbjct  120  LMEAIWTRFFPAIEALRAALSQGTLGELRVARAEFGKNFTHIPRSVDWAQAGGGLLDLGI  179

Query  178  HTMDQIISLFGRPDHVAYDIRSLRNKANPDDTFEAQLFY  216
            + +  I  +FG            R +   DDT    L Y
Sbjct  180  YCIQFISMVFGGQKPEKISAVGRRYETGVDDTVTVLLQY  218


>Q7JK39 Trans-1,2-dihydrobenzene-1,2-diol dehydrogenase [Macaca 
fuscata fuscata]
Length=334

 Score = 54.3 bits (129),  Expect = 2e-11
 Identities = 41/159 (26%), Positives = 64/159 (40%), Gaps = 1/159 (1%)

Query  59   EVLNDPDVKLVVVCTHADSHFEYAKRAMEAGKNVLVEKPFTPTLAQAKELFALAKSKGLT  118
            E+  DP+V++  V T    H       + AGK VL EKP     A+ +E+   A+S+GL 
Sbjct  60   ELAKDPNVEVAYVGTQHPQHKAAVMLCLAAGKAVLCEKPMGVNAAEVREMVTEARSRGLF  119

Query  119  VTPYQNRRFDSCFLTAKKAIESGKLGEIVEVESHF-DYYRPVAETKPGLPQDGAFYGLGV  177
            +      RF       +  +  G LG++    + F      V          GA   LG+
Sbjct  120  LMEAIWTRFFPASEALRSVLAQGTLGDLRVARAEFGKNLTHVPRAVDWAQAGGALLDLGI  179

Query  178  HTMDQIISLFGRPDHVAYDIRSLRNKANPDDTFEAQLFY  216
            + +  I  +FG        +   R++   DDT    L Y
Sbjct  180  YCVQFISMVFGGQKPEKISVMGRRHETGVDDTVTVLLQY  218


>Q9TQS6 Trans-1,2-dihydrobenzene-1,2-diol dehydrogenase [Macaca 
fascicularis]
Length=334

 Score = 54.3 bits (129),  Expect = 2e-11
 Identities = 41/159 (26%), Positives = 64/159 (40%), Gaps = 1/159 (1%)

Query  59   EVLNDPDVKLVVVCTHADSHFEYAKRAMEAGKNVLVEKPFTPTLAQAKELFALAKSKGLT  118
            E+  DP+V++  V T    H       + AGK VL EKP     A+ +E+   A+S+GL 
Sbjct  60   ELAKDPNVEVAYVGTQHPQHKAAVMLCLAAGKAVLCEKPMGVNAAEVREMVTEARSRGLF  119

Query  119  VTPYQNRRFDSCFLTAKKAIESGKLGEIVEVESHF-DYYRPVAETKPGLPQDGAFYGLGV  177
            +      RF       +  +  G LG++    + F      V          GA   LG+
Sbjct  120  LMEAIWTRFFPASEALRSVLAQGTLGDLRVARAEFGKNLTHVPRAVDWAQAGGALLDLGI  179

Query  178  HTMDQIISLFGRPDHVAYDIRSLRNKANPDDTFEAQLFY  216
            + +  I  +FG        +   R++   DDT    L Y
Sbjct  180  YCVQFISMVFGGQKPEKISVMGRRHETGVDDTVTVLLQY  218



Lambda      K        H        a         alpha
   0.320    0.137    0.407    0.792     4.96 

Gapped
Lambda      K        H        a         alpha    sigma
   0.267   0.0410    0.140     1.90     42.6     43.6 

Effective search space used: 1695870


  Database: c8408770500f670db1e9eaad0fff98c8.SwissProt.fasta
    Posted date:  Jun 1, 2024  8:46 AM
  Number of letters in database: 6,641
  Number of sequences in database:  19



Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Neighboring words threshold: 11
Window for multiple hits: 40