BLASTP 2.12.0+
Reference: Stephen F. Altschul, Thomas L. Madden, Alejandro A.
Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J.
Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of
protein database search programs", Nucleic Acids Res. 25:3389-3402.
Reference for composition-based statistics: Alejandro A. Schaffer,
L. Aravind, Thomas L. Madden, Sergei Shavirin, John L. Spouge, Yuri
I. Wolf, Eugene V. Koonin, and Stephen F. Altschul (2001),
"Improving the accuracy of PSI-BLAST protein database searches with
composition-based statistics and other refinements", Nucleic Acids
Res. 29:2994-3005.
Database: 22c80bf13cdfe6e7cf499fe8a5f7e602.SwissProt.fasta
22 sequences; 11,354 total letters
Query= Z1008
Length=414
Score E
Sequences producing significant alignments: (Bits) Value
P0AA85 Cardiolipin synthase B [Escherichia coli O157:H7] 845 0.0
P0AA84 Cardiolipin synthase B [Escherichia coli (strain K12)] 845 0.0
Q8FJN9 Cardiolipin synthase B [Escherichia coli O6:H1 (strain CFT... 839 0.0
P59715 Cardiolipin synthase B [Shigella flexneri] 837 0.0
Q8ZQP4 Cardiolipin synthase B [Salmonella typhimurium (strain LT2... 755 0.0
Q8Z883 Cardiolipin synthase B [Salmonella typhi] 755 0.0
Q5L1S5 Cardiolipin synthase [Geobacillus kaustophilus (strain HTA... 156 7e-46
A4IL76 Cardiolipin synthase [Geobacillus thermodenitrificans (str... 155 3e-45
C5D794 Cardiolipin synthase [Geobacillus sp. (strain WCH70)] 149 3e-43
O66043 Cardiolipin synthase [Alkalihalophilus pseudofirmus (strai... 149 3e-43
Q9HTH0 Cardiolipin synthase A [Pseudomonas aeruginosa (strain ATC... 147 1e-42
Q02DW8 Cardiolipin synthase A [Pseudomonas aeruginosa (strain UCB... 147 1e-42
B7V5T6 Cardiolipin synthase A [Pseudomonas aeruginosa (strain LES... 147 1e-42
P31048 Cardiolipin synthase A [Pseudomonas putida] 145 9e-42
P71040 Major cardiolipin synthase ClsA [Bacillus subtilis (strain... 144 2e-41
P45860 Probable cardiolipin synthase YwiE [Bacillus subtilis (str... 143 6e-41
Q0TQG9 Cardiolipin synthase [Clostridium perfringens (strain ATCC... 136 1e-38
P45865 Minor cardiolipin synthase ClsB [Bacillus subtilis (strain... 124 7e-35
P34001 Uncharacterized protein SMU_988 [Streptococcus mutans sero... 110 1e-29
P0A6H8 Cardiolipin synthase A [Escherichia coli (strain K12)] 107 2e-28
P75919 Cardiolipin synthase C [Escherichia coli (strain K12)] 86.7 2e-21
Q54Z25 Phospholipase D C [Dictyostelium discoideum] 38.1 1e-05
>P0AA85 Cardiolipin synthase B [Escherichia coli O157:H7]
Length=413
Score = 845 bits (2182), Expect = 0.0
Identities = 413/413 (100%), Positives = 413/413 (100%), Gaps = 0/413 (0%)
Query 1 MKCSWREGNKIQLLENGEQYYPAVFKAIGEAQERIILETFIWFEDDVGKQLHAALLAAAQ 60
MKCSWREGNKIQLLENGEQYYPAVFKAIGEAQERIILETFIWFEDDVGKQLHAALLAAAQ
Sbjct 1 MKCSWREGNKIQLLENGEQYYPAVFKAIGEAQERIILETFIWFEDDVGKQLHAALLAAAQ 60
Query 61 RGVKAEVLLDGYGSPDLSDEFVNELTAAGVVFRYYDPRPRLFGMRTNVFRRMHRKIVVID 120
RGVKAEVLLDGYGSPDLSDEFVNELTAAGVVFRYYDPRPRLFGMRTNVFRRMHRKIVVID
Sbjct 61 RGVKAEVLLDGYGSPDLSDEFVNELTAAGVVFRYYDPRPRLFGMRTNVFRRMHRKIVVID 120
Query 121 ARIAFIGGLNYSAEHMSSYGPEAKQDYAVRLEGPIVEDILQFELENLPGQSAARRWWRRH 180
ARIAFIGGLNYSAEHMSSYGPEAKQDYAVRLEGPIVEDILQFELENLPGQSAARRWWRRH
Sbjct 121 ARIAFIGGLNYSAEHMSSYGPEAKQDYAVRLEGPIVEDILQFELENLPGQSAARRWWRRH 180
Query 181 HKAEENRQPGEAQVLLVWRDNEEHRDDIERHYLKMLTQARREVIIANAYFFPGYRFLHAL 240
HKAEENRQPGEAQVLLVWRDNEEHRDDIERHYLKMLTQARREVIIANAYFFPGYRFLHAL
Sbjct 181 HKAEENRQPGEAQVLLVWRDNEEHRDDIERHYLKMLTQARREVIIANAYFFPGYRFLHAL 240
Query 241 RKAARRGVRIKLIIQGEPDMPIVRVGARLLYNYLVKGGVQVFEYRRRPLHGKVALMDDHW 300
RKAARRGVRIKLIIQGEPDMPIVRVGARLLYNYLVKGGVQVFEYRRRPLHGKVALMDDHW
Sbjct 241 RKAARRGVRIKLIIQGEPDMPIVRVGARLLYNYLVKGGVQVFEYRRRPLHGKVALMDDHW 300
Query 301 ATVGSSNLDPLSLSLNLEANVIIHDRHFNQTLRDNLNGIIAADCQQVDETMLPKRTWWNL 360
ATVGSSNLDPLSLSLNLEANVIIHDRHFNQTLRDNLNGIIAADCQQVDETMLPKRTWWNL
Sbjct 301 ATVGSSNLDPLSLSLNLEANVIIHDRHFNQTLRDNLNGIIAADCQQVDETMLPKRTWWNL 360
Query 361 TKSVLAFHFLRHFPALVGWLPAHTPRLAQVDPPAQPTMETQDRVETENTGVKP 413
TKSVLAFHFLRHFPALVGWLPAHTPRLAQVDPPAQPTMETQDRVETENTGVKP
Sbjct 361 TKSVLAFHFLRHFPALVGWLPAHTPRLAQVDPPAQPTMETQDRVETENTGVKP 413
>P0AA84 Cardiolipin synthase B [Escherichia coli (strain K12)]
Length=413
Score = 845 bits (2182), Expect = 0.0
Identities = 413/413 (100%), Positives = 413/413 (100%), Gaps = 0/413 (0%)
Query 1 MKCSWREGNKIQLLENGEQYYPAVFKAIGEAQERIILETFIWFEDDVGKQLHAALLAAAQ 60
MKCSWREGNKIQLLENGEQYYPAVFKAIGEAQERIILETFIWFEDDVGKQLHAALLAAAQ
Sbjct 1 MKCSWREGNKIQLLENGEQYYPAVFKAIGEAQERIILETFIWFEDDVGKQLHAALLAAAQ 60
Query 61 RGVKAEVLLDGYGSPDLSDEFVNELTAAGVVFRYYDPRPRLFGMRTNVFRRMHRKIVVID 120
RGVKAEVLLDGYGSPDLSDEFVNELTAAGVVFRYYDPRPRLFGMRTNVFRRMHRKIVVID
Sbjct 61 RGVKAEVLLDGYGSPDLSDEFVNELTAAGVVFRYYDPRPRLFGMRTNVFRRMHRKIVVID 120
Query 121 ARIAFIGGLNYSAEHMSSYGPEAKQDYAVRLEGPIVEDILQFELENLPGQSAARRWWRRH 180
ARIAFIGGLNYSAEHMSSYGPEAKQDYAVRLEGPIVEDILQFELENLPGQSAARRWWRRH
Sbjct 121 ARIAFIGGLNYSAEHMSSYGPEAKQDYAVRLEGPIVEDILQFELENLPGQSAARRWWRRH 180
Query 181 HKAEENRQPGEAQVLLVWRDNEEHRDDIERHYLKMLTQARREVIIANAYFFPGYRFLHAL 240
HKAEENRQPGEAQVLLVWRDNEEHRDDIERHYLKMLTQARREVIIANAYFFPGYRFLHAL
Sbjct 181 HKAEENRQPGEAQVLLVWRDNEEHRDDIERHYLKMLTQARREVIIANAYFFPGYRFLHAL 240
Query 241 RKAARRGVRIKLIIQGEPDMPIVRVGARLLYNYLVKGGVQVFEYRRRPLHGKVALMDDHW 300
RKAARRGVRIKLIIQGEPDMPIVRVGARLLYNYLVKGGVQVFEYRRRPLHGKVALMDDHW
Sbjct 241 RKAARRGVRIKLIIQGEPDMPIVRVGARLLYNYLVKGGVQVFEYRRRPLHGKVALMDDHW 300
Query 301 ATVGSSNLDPLSLSLNLEANVIIHDRHFNQTLRDNLNGIIAADCQQVDETMLPKRTWWNL 360
ATVGSSNLDPLSLSLNLEANVIIHDRHFNQTLRDNLNGIIAADCQQVDETMLPKRTWWNL
Sbjct 301 ATVGSSNLDPLSLSLNLEANVIIHDRHFNQTLRDNLNGIIAADCQQVDETMLPKRTWWNL 360
Query 361 TKSVLAFHFLRHFPALVGWLPAHTPRLAQVDPPAQPTMETQDRVETENTGVKP 413
TKSVLAFHFLRHFPALVGWLPAHTPRLAQVDPPAQPTMETQDRVETENTGVKP
Sbjct 361 TKSVLAFHFLRHFPALVGWLPAHTPRLAQVDPPAQPTMETQDRVETENTGVKP 413
>Q8FJN9 Cardiolipin synthase B [Escherichia coli O6:H1 (strain
CFT073 / ATCC 700928 / UPEC)]
Length=413
Score = 839 bits (2168), Expect = 0.0
Identities = 411/413 (99%), Positives = 412/413 (99%), Gaps = 0/413 (0%)
Query 1 MKCSWREGNKIQLLENGEQYYPAVFKAIGEAQERIILETFIWFEDDVGKQLHAALLAAAQ 60
MKCSWREGNKIQLLENGEQYYPAVFKAIGEAQERIILETFIWFEDDVGKQLHAALLAAAQ
Sbjct 1 MKCSWREGNKIQLLENGEQYYPAVFKAIGEAQERIILETFIWFEDDVGKQLHAALLAAAQ 60
Query 61 RGVKAEVLLDGYGSPDLSDEFVNELTAAGVVFRYYDPRPRLFGMRTNVFRRMHRKIVVID 120
RGVKAEVLLDGYGSPDLSDEFVNELTAAGVVFRYYDPRPRLFGMRTNVFRRMHRKIVVID
Sbjct 61 RGVKAEVLLDGYGSPDLSDEFVNELTAAGVVFRYYDPRPRLFGMRTNVFRRMHRKIVVID 120
Query 121 ARIAFIGGLNYSAEHMSSYGPEAKQDYAVRLEGPIVEDILQFELENLPGQSAARRWWRRH 180
ARIAFIGGLNYSAEHMSSYGPEAKQDYAVRLEGPIVEDILQFELENLPGQSAARRWWRRH
Sbjct 121 ARIAFIGGLNYSAEHMSSYGPEAKQDYAVRLEGPIVEDILQFELENLPGQSAARRWWRRH 180
Query 181 HKAEENRQPGEAQVLLVWRDNEEHRDDIERHYLKMLTQARREVIIANAYFFPGYRFLHAL 240
HKAEENRQPGEAQVLLVWRDNEEHRDDIERHYLKMLTQARREVIIANAYFFPGYRFLHAL
Sbjct 181 HKAEENRQPGEAQVLLVWRDNEEHRDDIERHYLKMLTQARREVIIANAYFFPGYRFLHAL 240
Query 241 RKAARRGVRIKLIIQGEPDMPIVRVGARLLYNYLVKGGVQVFEYRRRPLHGKVALMDDHW 300
RKAARRGVRIKLIIQGEPDMPIVRVGARLLYNYLVKGGVQVFEYRRRPLHGKVALMDDHW
Sbjct 241 RKAARRGVRIKLIIQGEPDMPIVRVGARLLYNYLVKGGVQVFEYRRRPLHGKVALMDDHW 300
Query 301 ATVGSSNLDPLSLSLNLEANVIIHDRHFNQTLRDNLNGIIAADCQQVDETMLPKRTWWNL 360
ATVGSSNLDPLSLSLNLEANVIIHDR+FNQTLRDNLNGIIAADCQQVDETMLPKRTWWNL
Sbjct 301 ATVGSSNLDPLSLSLNLEANVIIHDRNFNQTLRDNLNGIIAADCQQVDETMLPKRTWWNL 360
Query 361 TKSVLAFHFLRHFPALVGWLPAHTPRLAQVDPPAQPTMETQDRVETENTGVKP 413
TKSVLAFHFLRHFPALVGWLPAHTPRLAQV PPAQPTMETQDRVETENTGVKP
Sbjct 361 TKSVLAFHFLRHFPALVGWLPAHTPRLAQVGPPAQPTMETQDRVETENTGVKP 413
>P59715 Cardiolipin synthase B [Shigella flexneri]
Length=413
Score = 837 bits (2161), Expect = 0.0
Identities = 408/413 (99%), Positives = 411/413 (99%), Gaps = 0/413 (0%)
Query 1 MKCSWREGNKIQLLENGEQYYPAVFKAIGEAQERIILETFIWFEDDVGKQLHAALLAAAQ 60
MKCSWREGNKIQLLENGEQYYPAVFKAIGEAQERIILETFIWFED+VGKQLHAALLAAAQ
Sbjct 1 MKCSWREGNKIQLLENGEQYYPAVFKAIGEAQERIILETFIWFEDNVGKQLHAALLAAAQ 60
Query 61 RGVKAEVLLDGYGSPDLSDEFVNELTAAGVVFRYYDPRPRLFGMRTNVFRRMHRKIVVID 120
RGVKAEVLLDGYGSPDLSDEFVNELTAAGVVFRYYDPRPRLFGMRTNVFRRMHRKIVVID
Sbjct 61 RGVKAEVLLDGYGSPDLSDEFVNELTAAGVVFRYYDPRPRLFGMRTNVFRRMHRKIVVID 120
Query 121 ARIAFIGGLNYSAEHMSSYGPEAKQDYAVRLEGPIVEDILQFELENLPGQSAARRWWRRH 180
ARIAFIGGLNYS+EHMSSYGPEAKQDYAVRLEGPIVEDILQFELENLPGQSAARRWWRRH
Sbjct 121 ARIAFIGGLNYSSEHMSSYGPEAKQDYAVRLEGPIVEDILQFELENLPGQSAARRWWRRH 180
Query 181 HKAEENRQPGEAQVLLVWRDNEEHRDDIERHYLKMLTQARREVIIANAYFFPGYRFLHAL 240
HKAEENRQPGEAQVLLVWRDNEEHRDDIERHYLKMLTQA+REVIIANAYFFPGYRFLHAL
Sbjct 181 HKAEENRQPGEAQVLLVWRDNEEHRDDIERHYLKMLTQAQREVIIANAYFFPGYRFLHAL 240
Query 241 RKAARRGVRIKLIIQGEPDMPIVRVGARLLYNYLVKGGVQVFEYRRRPLHGKVALMDDHW 300
RKAARRGVRIKLIIQGEPDMPIVRVGARLLYNYLVKGGVQVFEYRRRPLHGKVALMDDHW
Sbjct 241 RKAARRGVRIKLIIQGEPDMPIVRVGARLLYNYLVKGGVQVFEYRRRPLHGKVALMDDHW 300
Query 301 ATVGSSNLDPLSLSLNLEANVIIHDRHFNQTLRDNLNGIIAADCQQVDETMLPKRTWWNL 360
ATVGSSNLDPLSLSLNLEANVIIHDRHFNQTLRDNLNGIIAADCQQVDETMLPKRTWWNL
Sbjct 301 ATVGSSNLDPLSLSLNLEANVIIHDRHFNQTLRDNLNGIIAADCQQVDETMLPKRTWWNL 360
Query 361 TKSVLAFHFLRHFPALVGWLPAHTPRLAQVDPPAQPTMETQDRVETENTGVKP 413
TKSVLAFHFLRHFPALVGWLPAHTPRL QVDPPAQPTMETQDRVETENTGV P
Sbjct 361 TKSVLAFHFLRHFPALVGWLPAHTPRLTQVDPPAQPTMETQDRVETENTGVNP 413
>Q8ZQP4 Cardiolipin synthase B [Salmonella typhimurium (strain
LT2 / SGSC1412 / ATCC 700720)]
Length=413
Score = 755 bits (1949), Expect = 0.0
Identities = 357/413 (86%), Positives = 388/413 (94%), Gaps = 0/413 (0%)
Query 1 MKCSWREGNKIQLLENGEQYYPAVFKAIGEAQERIILETFIWFEDDVGKQLHAALLAAAQ 60
MKC WREGN+IQLLENG+Q+YPAVF+AI +AQ++IILETFI FED+VGK+LH ALL AAQ
Sbjct 1 MKCGWREGNQIQLLENGDQFYPAVFEAIAQAQQKIILETFILFEDEVGKKLHTALLKAAQ 60
Query 61 RGVKAEVLLDGYGSPDLSDEFVNELTAAGVVFRYYDPRPRLFGMRTNVFRRMHRKIVVID 120
RGVKAEVLLDGYGSPDLSD FV ELT+AGV+FRYYDPRPRL G+RTN+FRRMHRKIVVID
Sbjct 61 RGVKAEVLLDGYGSPDLSDAFVGELTSAGVIFRYYDPRPRLLGLRTNIFRRMHRKIVVID 120
Query 121 ARIAFIGGLNYSAEHMSSYGPEAKQDYAVRLEGPIVEDILQFELENLPGQSAARRWWRRH 180
RIAF+GG+NYSAEHMS YGP+AKQDYAVR+EGP+V DILQFE+ENLPGQS ARRWW+RH
Sbjct 121 DRIAFVGGINYSAEHMSDYGPQAKQDYAVRVEGPVVADILQFEVENLPGQSPARRWWKRH 180
Query 181 HKAEENRQPGEAQVLLVWRDNEEHRDDIERHYLKMLTQARREVIIANAYFFPGYRFLHAL 240
H+AEENR PGEAQ L VWRDNEEHRDDIERHYLKMLTQA+REVIIANAYFFPGYR LHA+
Sbjct 181 HQAEENRHPGEAQALFVWRDNEEHRDDIERHYLKMLTQAKREVIIANAYFFPGYRLLHAM 240
Query 241 RKAARRGVRIKLIIQGEPDMPIVRVGARLLYNYLVKGGVQVFEYRRRPLHGKVALMDDHW 300
RKAARRGV +KLI+QGEPDMPIV+VGARLLYNYLVKGGVQV+EYRRRPLHGKVALMDDHW
Sbjct 241 RKAARRGVSVKLIVQGEPDMPIVKVGARLLYNYLVKGGVQVYEYRRRPLHGKVALMDDHW 300
Query 301 ATVGSSNLDPLSLSLNLEANVIIHDRHFNQTLRDNLNGIIAADCQQVDETMLPKRTWWNL 360
ATVGSSNLDPLSLSLNLEAN+IIHDR FNQTLRDNL GII DC+QVDE+MLPKRTWWNL
Sbjct 301 ATVGSSNLDPLSLSLNLEANLIIHDRTFNQTLRDNLQGIIVNDCKQVDESMLPKRTWWNL 360
Query 361 TKSVLAFHFLRHFPALVGWLPAHTPRLAQVDPPAQPTMETQDRVETENTGVKP 413
TKSVLAFHFLRHFPALVGWLPAHTP LAQV PPAQP METQDRV+ ENTGVKP
Sbjct 361 TKSVLAFHFLRHFPALVGWLPAHTPHLAQVPPPAQPEMETQDRVDPENTGVKP 413
>Q8Z883 Cardiolipin synthase B [Salmonella typhi]
Length=413
Score = 755 bits (1949), Expect = 0.0
Identities = 357/413 (86%), Positives = 389/413 (94%), Gaps = 0/413 (0%)
Query 1 MKCSWREGNKIQLLENGEQYYPAVFKAIGEAQERIILETFIWFEDDVGKQLHAALLAAAQ 60
MKC WREGN+IQLLENG+Q+YPAVF+AI +AQ++IILETFI FED+VGK+LHAALL AAQ
Sbjct 1 MKCGWREGNQIQLLENGDQFYPAVFEAIAQAQQKIILETFILFEDEVGKKLHAALLKAAQ 60
Query 61 RGVKAEVLLDGYGSPDLSDEFVNELTAAGVVFRYYDPRPRLFGMRTNVFRRMHRKIVVID 120
RGVKAEVLLDGYGSPDLSD FV ELT+AGV+FRYYDPRPRL G+RTN+FRRMHRKIVVID
Sbjct 61 RGVKAEVLLDGYGSPDLSDAFVGELTSAGVIFRYYDPRPRLLGLRTNIFRRMHRKIVVID 120
Query 121 ARIAFIGGLNYSAEHMSSYGPEAKQDYAVRLEGPIVEDILQFELENLPGQSAARRWWRRH 180
RIAF+GG+NYSAEHMS YGP+AKQDYAVR+EGP+V DILQFE+ENLPGQS ARRWW+RH
Sbjct 121 DRIAFVGGINYSAEHMSDYGPQAKQDYAVRVEGPVVADILQFEVENLPGQSPARRWWKRH 180
Query 181 HKAEENRQPGEAQVLLVWRDNEEHRDDIERHYLKMLTQARREVIIANAYFFPGYRFLHAL 240
H+AEENR PGEAQ L VWRDNEEHRDDIERHYLKMLTQA+REVIIANAYFFPGYR LHA+
Sbjct 181 HQAEENRHPGEAQALFVWRDNEEHRDDIERHYLKMLTQAKREVIIANAYFFPGYRLLHAM 240
Query 241 RKAARRGVRIKLIIQGEPDMPIVRVGARLLYNYLVKGGVQVFEYRRRPLHGKVALMDDHW 300
RKAARRGV +KLI+QGEPDMPIV+VGARLLYNYLVKGGVQV+EYRRRPLHGKVALMDDHW
Sbjct 241 RKAARRGVSVKLIVQGEPDMPIVKVGARLLYNYLVKGGVQVYEYRRRPLHGKVALMDDHW 300
Query 301 ATVGSSNLDPLSLSLNLEANVIIHDRHFNQTLRDNLNGIIAADCQQVDETMLPKRTWWNL 360
ATVGSSNLDPLSLSLNLEAN+IIHDR FNQTLRDNL GII DC+QVDE+MLPKRTWWNL
Sbjct 301 ATVGSSNLDPLSLSLNLEANLIIHDRTFNQTLRDNLQGIIVNDCKQVDESMLPKRTWWNL 360
Query 361 TKSVLAFHFLRHFPALVGWLPAHTPRLAQVDPPAQPTMETQDRVETENTGVKP 413
TKSVLAFHFLRHFPALVGWLPAHTP LAQV PPAQP METQDRV+ EN+GVKP
Sbjct 361 TKSVLAFHFLRHFPALVGWLPAHTPHLAQVPPPAQPEMETQDRVDPENSGVKP 413
>Q5L1S5 Cardiolipin synthase [Geobacillus kaustophilus (strain
HTA426)]
Length=502
Score = 156 bits (395), Expect = 7e-46
Identities = 97/315 (31%), Positives = 168/315 (53%), Gaps = 6/315 (2%)
Query 13 LLENGEQYYPAVFKAIGEAQERIILETFIWFEDDVGKQLHAALLAAAQRGVKAEVLLDGY 72
+L NGE+ + ++F + +A+ I LE +I D++G+QL L+ A++GV+ L D
Sbjct 143 VLTNGEETFSSIFAELEKAEHHIHLEYYIVRHDEIGQQLKRVLMEKARQGVRVRFLYDAV 202
Query 73 GSPDLSDEFVNELTAAGVVFRYYDPRPRLFGMRTNVFRRMHRKIVVIDARIAFIGGLNYS 132
GS LS+ ++ EL AAGV + P RL + + R HRKI+VID + F+GGLN
Sbjct 203 GSWKLSNAYIEELRAAGVEMIPFSP-VRLPFLSNQINFRNHRKIIVIDGGVGFVGGLNIG 261
Query 133 AEHMSS---YGPEAKQDYAVRLEGPIVEDILQFELENLPGQSAARRWWRRHHKAEENRQP 189
E++ +G +D + + G V + L++ + R + +
Sbjct 262 DEYLGKNKYFG--FWRDTHLLIRGEAVRTLQLIFLQDWYYMTGERLLTPDYLSPPLIVEE 319
Query 190 GEAQVLLVWRDNEEHRDDIERHYLKMLTQARREVIIANAYFFPGYRFLHALRKAARRGVR 249
G+ V L+ ++ + I++ Y M+T A+R + +A+ YF P L AL+ AA G+
Sbjct 320 GQGGVQLIAGGPDQKWEVIKQLYFAMITSAKRSIWVASPYFVPDEDILTALKVAALSGID 379
Query 250 IKLIIQGEPDMPIVRVGARLLYNYLVKGGVQVFEYRRRPLHGKVALMDDHWATVGSSNLD 309
++L+ PD IV +R + L++ GV+++EY + LH KV ++D A++G++N+D
Sbjct 380 VRLLAPKRPDKKIVFYASRSYFPELLEAGVKIYEYEKGFLHSKVIVVDGELASIGTANMD 439
Query 310 PLSLSLNLEANVIIH 324
S LN E N ++
Sbjct 440 MRSFHLNFEVNAFLY 454
>A4IL76 Cardiolipin synthase [Geobacillus thermodenitrificans
(strain NG80-2)]
Length=502
Score = 155 bits (391), Expect = 3e-45
Identities = 98/315 (31%), Positives = 166/315 (53%), Gaps = 6/315 (2%)
Query 13 LLENGEQYYPAVFKAIGEAQERIILETFIWFEDDVGKQLHAALLAAAQRGVKAEVLLDGY 72
+L NGE+ + A+F + +AQ I LE +I D++G++L L+ A +GV L D
Sbjct 143 VLTNGEETFAAIFDELEKAQHHIHLEYYIVRHDEIGQKLKHVLMEKACQGVHVRFLYDAV 202
Query 73 GSPDLSDEFVNELTAAGVVFRYYDPRPRLFGMRTNVFRRMHRKIVVIDARIAFIGGLNYS 132
GS LS+ ++ EL AAGV + P RL + + R HRKI+VID + F+GGLN
Sbjct 203 GSWKLSNAYIEELRAAGVEMIPFSP-VRLPFLSNQINFRNHRKIIVIDGGVGFVGGLNIG 261
Query 133 AEHMSS---YGPEAKQDYAVRLEGPIVEDILQFELENLPGQSAARRWWRRHHKAEENRQP 189
E++ +G +D + + G V + L++ + R + +
Sbjct 262 DEYLGKDEYFG--FWRDTHLLIRGEAVRTLQLIFLQDWYYMTGERLLTPEYLSPPLIVEE 319
Query 190 GEAQVLLVWRDNEEHRDDIERHYLKMLTQARREVIIANAYFFPGYRFLHALRKAARRGVR 249
G+ V L+ ++ + I++ Y M+T A+R + +A+ YF P L AL+ AA G+
Sbjct 320 GQGGVQLIAGGPDQKWEVIKQLYFAMITSAKRSIWVASPYFVPDEDILTALKVAALSGID 379
Query 250 IKLIIQGEPDMPIVRVGARLLYNYLVKGGVQVFEYRRRPLHGKVALMDDHWATVGSSNLD 309
++L+ PD IV +R + L++ GV+++EY + LH KV ++D A++G++N+D
Sbjct 380 VRLLAPKRPDKKIVFYASRSYFPELLEAGVKIYEYEKGFLHSKVIVVDGELASIGTANMD 439
Query 310 PLSLSLNLEANVIIH 324
S LN E N ++
Sbjct 440 MRSFHLNFEVNAFLY 454
>C5D794 Cardiolipin synthase [Geobacillus sp. (strain WCH70)]
Length=502
Score = 149 bits (377), Expect = 3e-43
Identities = 97/316 (31%), Positives = 162/316 (51%), Gaps = 6/316 (2%)
Query 12 QLLENGEQYYPAVFKAIGEAQERIILETFIWFEDDVGKQLHAALLAAAQRGVKAEVLLDG 71
++L NGE+ + +F+ + +A I LE +I D+VG++L L+ A++GV L D
Sbjct 142 RVLTNGEETFSTIFEELEKATHHIHLEYYIVRHDEVGQKLKTILIEKAKKGVHVRFLYDA 201
Query 72 YGSPDLSDEFVNELTAAGVVFRYYDPRPRLFGMRTNVFRRMHRKIVVIDARIAFIGGLNY 131
GS LS ++ EL AGV + P F T FR HRKI+VID I F+GGLN
Sbjct 202 VGSWKLSKTYIQELRDAGVEMIPFSPVRLPFLSNTINFRN-HRKIIVIDGTIGFVGGLNI 260
Query 132 SAEHMSS---YGPEAKQDYAVRLEGPIVEDILQFELENLPGQSAARRWWRRHHKAEENRQ 188
E++ +G +D + + G V + L++ + + E
Sbjct 261 GDEYLGKDKYFG--FWRDTHLWIRGEAVRTLQLIFLQDWYYMTGKTLLTPEYLSPELVHY 318
Query 189 PGEAQVLLVWRDNEEHRDDIERHYLKMLTQARREVIIANAYFFPGYRFLHALRKAARRGV 248
G+ V L+ ++ + I+ Y M+T A+R + IA+ YF P L AL+ AA G+
Sbjct 319 DGQGGVQLIAGGPDQKWEVIKHLYFAMITSAQRSIWIASPYFVPDEDILTALKIAALSGL 378
Query 249 RIKLIIQGEPDMPIVRVGARLLYNYLVKGGVQVFEYRRRPLHGKVALMDDHWATVGSSNL 308
++++ PD IV +R + L++ GV+++EY + LH K+ ++D A++G++N+
Sbjct 379 DVRILAPKRPDKKIVFYASRSYFPELLEAGVKIYEYSKGFLHSKIMIVDGELASIGTANM 438
Query 309 DPLSLSLNLEANVIIH 324
D S LN E N ++
Sbjct 439 DMRSFHLNFEVNAFLY 454
>O66043 Cardiolipin synthase [Alkalihalophilus pseudofirmus (strain
ATCC BAA-2126 / JCM 17055 / OF4)]
Length=503
Score = 149 bits (377), Expect = 3e-43
Identities = 95/320 (30%), Positives = 167/320 (52%), Gaps = 8/320 (3%)
Query 9 NKIQLLENGEQYYPAVFKAIGEAQERIILETFIWFEDDVGKQLHAALLAAAQRGVKAEVL 68
++ ++L +G++ Y + +A+ A+ I LE +I DD+G Q+ L++ A+ GV L
Sbjct 140 SETKVLTDGKETYAHILQALKMAEHHIHLEYYIVRHDDLGNQIKDILISKAKEGVHVRFL 199
Query 69 LDGYGSPDLSDEFVNELTAAGVVFRYYDPRPRLFGMRTNVFRRMHRKIVVIDARIAFIGG 128
DG GS LS +V EL AGV + P F T +R HRKI+VID + F+GG
Sbjct 200 YDGVGSWKLSKSYVEELRDAGVEMVSFSPVKLPFLTHTINYRN-HRKIIVIDGVVGFVGG 258
Query 129 LNYSAEHMSSYGPEAK----QDYAVRLEGPIVEDILQFELENLPGQSAARRWWRRHHKAE 184
LN E++ G +A +D + + G V + L++ Q+ + +
Sbjct 259 LNIGDEYL---GKDAYFGYWRDTHLYVRGEAVRTLQLIFLQDWHYQTGETILNQTYLSPS 315
Query 185 ENRQPGEAQVLLVWRDNEEHRDDIERHYLKMLTQARREVIIANAYFFPGYRFLHALRKAA 244
+ G+ V ++ + + ++ + M+T A++ + IA+ YF P L AL+ AA
Sbjct 316 LSMTKGDGGVQMIASGPDTRWEVNKKLFFSMITSAKKSIWIASPYFIPDDDILSALKIAA 375
Query 245 RRGVRIKLIIQGEPDMPIVRVGARLLYNYLVKGGVQVFEYRRRPLHGKVALMDDHWATVG 304
G+ +++++ PD IV +R + L++ GV+V+EY R +H K+ ++D A++G
Sbjct 376 LSGIDVRILVPNRPDKRIVFHASRSYFPELLEAGVKVYEYNRGFMHSKIIIVDHEIASIG 435
Query 305 SSNLDPLSLSLNLEANVIIH 324
+SN+D S LN E N ++
Sbjct 436 TSNMDMRSFHLNFEVNAYLY 455
>Q9HTH0 Cardiolipin synthase A [Pseudomonas aeruginosa (strain
ATCC 15692 / DSM 22644 / CIP 104116 / JCM 14847 / LMG 12228
/ 1C / PRS 101 / PAO1)]
Length=490
Score = 147 bits (371), Expect = 1e-42
Identities = 105/326 (32%), Positives = 155/326 (48%), Gaps = 16/326 (5%)
Query 9 NKIQLLENGEQYYPAVFKAIGEAQERIILETFIWFEDDVGKQLHAALLAAAQRGVKAEVL 68
N+++LL NGE + A+FKAI A++ I+++ FI +D +G++L LL A GV+ L
Sbjct 131 NRVRLLVNGEASFEAMFKAISAARQVILVQFFIVRDDALGQRLQQLLLERAANGVEVFFL 190
Query 69 LDGYGSPDLSDEFVNELTAAGVVFRYYDPRPRLFGMRTNVFRRMHRKIVVIDARIAFIGG 128
D GS L +V L GV + + R V R HRK+VV+D F+GG
Sbjct 191 YDAIGSHALPHRYVERLRQGGVQMHGFSTGSGMLN-RFQVNFRNHRKVVVVDGECGFVGG 249
Query 129 LNYSAEHMSSYGPEAK-QDYAVRLEGPIVEDILQFELENLPGQSAARRWWRRHHKAEENR 187
N E++ P A +D + L GP V + + S A W+ H
Sbjct 250 HNVGVEYLGEKPPLAPWRDTHMELRGPAVACLQE---------SFAEDWYWATHSLPPLI 300
Query 188 QPGE-----AQVLLVWRDNEEHRDDIERHYLKMLTQARREVIIANAYFFPGYRFLHALRK 242
P + A +V + ++ +++M+ A V I + YF P + ALR
Sbjct 301 LPPQYDSEGALCQVVASGPADAQETCSLFFVEMINAAHERVWITSPYFVPDEAVMAALRL 360
Query 243 AARRGVRIKLIIQGEPDMPIVRVGARLLYNYLVKGGVQVFEYRRRPLHGKVALMDDHWAT 302
A RGV ++L+I PD V + L ++ GV+VF Y+ LH KV L+D A
Sbjct 361 AVLRGVDVRLLIPSRPDHRTVYAASSLYALEAIRAGVKVFRYQPGFLHQKVVLVDRDTAA 420
Query 303 VGSSNLDPLSLSLNLEANVIIHDRHF 328
VGS+NLD S LN E V+ D F
Sbjct 421 VGSANLDNRSFRLNFEVMVVTVDEGF 446
>Q02DW8 Cardiolipin synthase A [Pseudomonas aeruginosa (strain
UCBPP-PA14)]
Length=490
Score = 147 bits (371), Expect = 1e-42
Identities = 105/326 (32%), Positives = 155/326 (48%), Gaps = 16/326 (5%)
Query 9 NKIQLLENGEQYYPAVFKAIGEAQERIILETFIWFEDDVGKQLHAALLAAAQRGVKAEVL 68
N+++LL NGE + A+FKAI A++ I+++ FI +D +G++L LL A GV+ L
Sbjct 131 NRVRLLVNGEASFEAMFKAISAARQVILVQFFIVRDDALGQRLQQLLLERAANGVEVFFL 190
Query 69 LDGYGSPDLSDEFVNELTAAGVVFRYYDPRPRLFGMRTNVFRRMHRKIVVIDARIAFIGG 128
D GS L +V L GV + + R V R HRK+VV+D F+GG
Sbjct 191 YDAIGSHALPHRYVERLRQGGVQMHGFSTGSGMLN-RFQVNFRNHRKVVVVDGECGFVGG 249
Query 129 LNYSAEHMSSYGPEAK-QDYAVRLEGPIVEDILQFELENLPGQSAARRWWRRHHKAEENR 187
N E++ P A +D + L GP V + + S A W+ H
Sbjct 250 HNVGVEYLGEKPPLAPWRDTHMELRGPAVACLQE---------SFAEDWYWATHSLPPLI 300
Query 188 QPGE-----AQVLLVWRDNEEHRDDIERHYLKMLTQARREVIIANAYFFPGYRFLHALRK 242
P + A +V + ++ +++M+ A V I + YF P + ALR
Sbjct 301 LPPQYDSEGALCQVVASGPADAQETCSLFFVEMINAAHERVWITSPYFVPDEAVMAALRL 360
Query 243 AARRGVRIKLIIQGEPDMPIVRVGARLLYNYLVKGGVQVFEYRRRPLHGKVALMDDHWAT 302
A RGV ++L+I PD V + L ++ GV+VF Y+ LH KV L+D A
Sbjct 361 AVLRGVDVRLLIPSRPDHRTVYAASSLYALEAIRAGVKVFRYQPGFLHQKVVLVDRDTAA 420
Query 303 VGSSNLDPLSLSLNLEANVIIHDRHF 328
VGS+NLD S LN E V+ D F
Sbjct 421 VGSANLDNRSFRLNFEVMVVTVDEGF 446
>B7V5T6 Cardiolipin synthase A [Pseudomonas aeruginosa (strain
LESB58)]
Length=490
Score = 147 bits (371), Expect = 1e-42
Identities = 105/326 (32%), Positives = 155/326 (48%), Gaps = 16/326 (5%)
Query 9 NKIQLLENGEQYYPAVFKAIGEAQERIILETFIWFEDDVGKQLHAALLAAAQRGVKAEVL 68
N+++LL NGE + A+FKAI A++ I+++ FI +D +G++L LL A GV+ L
Sbjct 131 NRVRLLVNGEASFEAMFKAISAARQVILVQFFIVRDDALGQRLQQLLLERAANGVEVFFL 190
Query 69 LDGYGSPDLSDEFVNELTAAGVVFRYYDPRPRLFGMRTNVFRRMHRKIVVIDARIAFIGG 128
D GS L +V L GV + + R V R HRK+VV+D F+GG
Sbjct 191 YDAIGSHALPHRYVERLRQGGVQMHGFSTGSGMLN-RFQVNFRNHRKVVVVDGECGFVGG 249
Query 129 LNYSAEHMSSYGPEAK-QDYAVRLEGPIVEDILQFELENLPGQSAARRWWRRHHKAEENR 187
N E++ P A +D + L GP V + + S A W+ H
Sbjct 250 HNVGVEYLGEKPPLAPWRDTHMELRGPAVACLQE---------SFAEDWYWATHSLPPLI 300
Query 188 QPGE-----AQVLLVWRDNEEHRDDIERHYLKMLTQARREVIIANAYFFPGYRFLHALRK 242
P + A +V + ++ +++M+ A V I + YF P + ALR
Sbjct 301 LPPQYDSEGALCQVVASGPADAQETCSLFFVEMINAAHERVWITSPYFVPDEAVMAALRL 360
Query 243 AARRGVRIKLIIQGEPDMPIVRVGARLLYNYLVKGGVQVFEYRRRPLHGKVALMDDHWAT 302
A RGV ++L+I PD V + L ++ GV+VF Y+ LH KV L+D A
Sbjct 361 AVLRGVDVRLLIPSRPDHRTVYAASSLYALEAIRAGVKVFRYQPGFLHQKVVLVDRDTAA 420
Query 303 VGSSNLDPLSLSLNLEANVIIHDRHF 328
VGS+NLD S LN E V+ D F
Sbjct 421 VGSANLDNRSFRLNFEVMVVTVDEGF 446
>P31048 Cardiolipin synthase A [Pseudomonas putida]
Length=481
Score = 145 bits (365), Expect = 9e-42
Identities = 109/354 (31%), Positives = 171/354 (48%), Gaps = 34/354 (10%)
Query 9 NKIQLLENGEQYYPAVFKAIGEAQERIILETFIWFEDDVGKQLHAALLAAAQRGVKAEVL 68
N+++LL NG+ + A+F AI +A++ ++++ FI +D +GK L LL A GV+ VL
Sbjct 122 NQVKLLVNGKATFDAIFAAIEKARDVVLVQFFIIHDDTLGKALQQLLLRKAAEGVQVFVL 181
Query 69 LDGYGSPDLSDEFVNELTAAGVVFRYYDPRPRLFGMRTNVFRRMHRKIVVIDARIAFIGG 128
D GS L + +L GV + R F R V R HRKIVV+D + FIGG
Sbjct 182 YDRVGSHALPASYSQQLRNGGVQIHAFATRRGWFN-RFQVNFRNHRKIVVVDGLLGFIGG 240
Query 129 LNYSAEHMSSYGPEAK--QDYAVRLEGPIVEDILQFELENLPGQSAARRWWRRHHKAEEN 186
N E++ + P+ +D V++ GP++ + +S A W+
Sbjct 241 HNVGDEYLGGH-PQLSPWRDTHVQISGPVLACL---------QESFAEDWY------WAT 284
Query 187 RQPGEAQVLLVWRDN-----------EEHRDDIERHYLKMLTQARREVIIANAYFFPGYR 235
RQ + + DN + ++ +L+ + A R V I + YF P
Sbjct 285 RQLPPLILPDAYPDNGVLCQALASGPADPQETCSLFFLEAIHSATRRVWITSPYFIPDEA 344
Query 236 FLHALRKAARRGVRIKLIIQGEPDMPIVRVGARLLYNYLVKGGVQVFEYRRRPLHGKVAL 295
ALR A RGV ++++I PD IV + L V+ GV++F Y+ LH KV L
Sbjct 345 VFAALRLAVLRGVDVRVLIPSRPDHRIVYAASSLFAFEAVRAGVRMFRYQPGFLHQKVVL 404
Query 296 MDDHWATVGSSNLDPLSLSLNLEANVIIHDRHFNQTLRDNLNGIIAADCQQVDE 349
+DD + +GS+NLD S LN E ++ DR+F D + ++ D +Q E
Sbjct 405 VDDEVSAIGSANLDNRSFRLNFEITLLTVDRNF----ADQVEHMLIKDFEQARE 454
>P71040 Major cardiolipin synthase ClsA [Bacillus subtilis (strain
168)]
Length=482
Score = 144 bits (363), Expect = 2e-41
Identities = 102/362 (28%), Positives = 173/362 (48%), Gaps = 8/362 (2%)
Query 7 EGNKIQLLENGEQYYPAVFKAIGEAQERIILETFIWFEDDVGKQLHAALLAAAQRGVKAE 66
E N + ++ +G + + I +A++ I L+ +I+ D++GK+L AL+ A+ GV+
Sbjct 117 EDNSVDVITDGRDKFQRLLSDISKAKDHIHLQYYIYKGDELGKKLRDALIQKAKEGVQVR 176
Query 67 VLLDGYGSPDLSDEFVNELT-AAGVVFRYYDPRPRLFGMRTNVFRRMHRKIVVIDARIAF 125
VL D GS L +F EL A G V ++ + R +R N R HRK+V+ID +
Sbjct 177 VLYDELGSRTLRKKFFKELREAGGHVEVFFPSKLRPINLRLNY--RNHRKLVIIDGMTGY 234
Query 126 IGGLNYSAEHMSSYGPEAK--QDYAVRLEGPIVEDI-LQFELENLPGQSAARRWWRRHHK 182
+GG N E++ P+ +D +RL+G V I +F L+ + +H
Sbjct 235 VGGFNVGDEYLG-LNPKFGYWRDTHIRLQGTAVHAIQTRFILDWNQASHHHTLTYIPNHF 293
Query 183 AEENRQPGEAQVLLVWRDNEEHRDDIERHYLKMLTQARREVIIANAYFFPGYRFLHALRK 242
+ + G + +V + + I+ Y+KM++ A+R ++I YF P L ALR
Sbjct 294 PDYGPK-GNVGMQIVTSGPDSEWEQIKNGYIKMISNAKRSILIQTPYFIPDASLLDALRI 352
Query 243 AARRGVRIKLIIQGEPDMPIVRVGARLLYNYLVKGGVQVFEYRRRPLHGKVALMDDHWAT 302
A G+ + ++I +PD V L+K G V+ Y +H K ++DD A+
Sbjct 353 ACLSGIDVNIMIPNKPDHAFVYWATLSYIGDLLKAGATVYIYDNGFIHAKTIVVDDEIAS 412
Query 303 VGSSNLDPLSLSLNLEANVIIHDRHFNQTLRDNLNGIIAADCQQVDETMLPKRTWWNLTK 362
VG++N+D S LN E N I+D + L + + E L + W + +
Sbjct 413 VGTANIDVRSFRLNFEVNAFIYDITIAKKLVSTFKEDLLVSRKFTYEEYLQRPLWIRIKE 472
Query 363 SV 364
SV
Sbjct 473 SV 474
>P45860 Probable cardiolipin synthase YwiE [Bacillus subtilis
(strain 168)]
Length=500
Score = 143 bits (360), Expect = 6e-41
Identities = 99/336 (29%), Positives = 175/336 (52%), Gaps = 26/336 (8%)
Query 9 NKIQLLENGEQYYPAVFKAIGEAQERIILETFIWFEDDVGKQLHAALLAAAQRGVKAEVL 68
+ I++L+NGE+ +P +FKA+ +A+ I +E +++ D +G+ + ++ A++GV+ L
Sbjct 139 SNIKVLKNGEETFPDIFKAMRKAESYIHIEYYMFKSDMLGRGMMDIMMEKARQGVEVRFL 198
Query 69 LDGYGSPDLSDEFVNELTAAGVVFRYYDP-RPRLFGMRTNVFRRMHRKIVVIDARIAFIG 127
D GS L+ + + AGV + P + F + N R HRKIV+ID + F+G
Sbjct 199 YDAAGSMKLARRDIMRMKQAGVDIVPFSPLKYGFFNQKLNF--RNHRKIVIIDGKTGFVG 256
Query 128 GLNYSAEHMSSYGPEAK--QDYAVRLEGPIVED---ILQFELENLPGQSAARRWWRRHHK 182
GLN E++S P +D +RLEG IV+ I + E + + +
Sbjct 257 GLNVGKEYISR-DPYIGFWRDTHLRLEGEIVQTLHAIFMLDWEYVSNEVLIDQ------- 308
Query 183 AEENRQP------GEAQVLLVWRDNEEHRDDIERHYLKMLTQARREVIIANAYFFPGYRF 236
EE P G Q++ D +E D+ Y +M++ A++ + IA YF P
Sbjct 309 -EEYNTPVPVEGGGIYQIVATGPDMKESMSDL---YYEMISSAQKSIWIATPYFVPNESI 364
Query 237 LHALRKAARRGVRIKLIIQGEPDMPIVRVGARLLYNYLVKGGVQVFEYRRRPLHGKVALM 296
AL+ AA +GV +++++ + D + + +R + L+ G++V+ Y++ +H KV ++
Sbjct 365 RTALKAAATKGVEVRVMVPEKNDSFLTQYASRSYFPELLLEGIEVYSYQKGFMHQKVMII 424
Query 297 DDHWATVGSSNLDPLSLSLNLEANVIIHDRHFNQTL 332
D A+VG++N+D S LN E NV D +TL
Sbjct 425 DGDLASVGTANMDMRSFQLNFEVNVFFTDAEAIRTL 460
>Q0TQG9 Cardiolipin synthase [Clostridium perfringens (strain
ATCC 13124 / DSM 756 / JCM 1290 / NCIMB 6125 / NCTC 8237 / Type
A)]
Length=476
Score = 136 bits (342), Expect = 1e-38
Identities = 89/339 (26%), Positives = 177/339 (52%), Gaps = 13/339 (4%)
Query 4 SWREGNKIQLLENGEQYYPAVFKAIGEAQERIILETFIWFEDDVGKQLHAALLAAAQRGV 63
++ + N I L + + + I +A++ I +E +I+ D++GK++ AL A+ GV
Sbjct 105 TYTQRNDIDLYFDANSLFEEMIDEINKAEKFIHMEFYIFKSDEIGKKILQALTKKAKEGV 164
Query 64 KAEVLLDGYGSPDLSDEFVNELTAAGVVFRYYDPR-PRLFGMRTNVFRRMHRKIVVIDAR 122
+ ++L+D G+ + + +++L AAG F+ + P + +R N R HRKI++ID++
Sbjct 165 EVKLLVDSIGN-SIHKKDIDKLKAAGGDFKIFFPGFCKYINLRINY--RNHRKILIIDSK 221
Query 123 IAFIGGLNYSAEHMSSYGPEAK-QDYAVRLEGPIVEDI-----LQFELENLPGQSA-ARR 175
+AF+GG N E++ +D +++G + D+ L + N ++
Sbjct 222 VAFLGGFNIGDEYLGKDKNIGHWRDTHTKIKGLAINDLEGRFLLDWSYANESDLDIDLKK 281
Query 176 WWRRHHKAEENRQPGEAQVLLVWRDNEEHRDDIERHYLKMLTQARREVIIANAYFFPGYR 235
++ H + ++ AQ++ D+ E + I+ Y K++ A++ + I YF P
Sbjct 282 YFINPHSTDLPKKIIGAQIVSSGPDHTEQQ--IKNGYFKIINSAKKNLFIQTPYFVPDEP 339
Query 236 FLHALRKAARRGVRIKLIIQGEPDMPIVRVGARLLYNYLVKGGVQVFEYRRRPLHGKVAL 295
L ALR AA GV +K+++ G PD + A + L+ G +++ Y + LH K +
Sbjct 340 MLEALRLAALSGVDVKIMLPGNPDHKFMGWIANSYFESLLNAGAKIYLYEKGFLHAKTIV 399
Query 296 MDDHWATVGSSNLDPLSLSLNLEANVIIHDRHFNQTLRD 334
D +VG++N+D S SLN E+N+ I++ ++++ +
Sbjct 400 ADSSICSVGTANMDIRSFSLNFESNIFIYNEAISKSMEE 438
>P45865 Minor cardiolipin synthase ClsB [Bacillus subtilis (strain
168)]
Length=398
Score = 124 bits (312), Expect = 7e-35
Identities = 93/330 (28%), Positives = 151/330 (46%), Gaps = 22/330 (7%)
Query 6 REGNKIQLLENGEQYYPAVFKAIGEAQERIILETFIWFEDDVGKQLHAALLAAAQRGVKA 65
++ + I+L+ G + I +A + + FI D+V ++ L AQ GV
Sbjct 40 KKKSDIELIHCGADLVERMMNDIRQAASSVHMMFFIMKNDEVSHNMYTLLKTKAQAGVSV 99
Query 66 EVLLDGYGSPDLSDEFVNELTAAGVVFRYYDPRPRLFGMRTNVFRRMHRKIVVIDARIAF 125
+LLD G + + + AGV + RPR ++ +R HRKI VID +I +
Sbjct 100 YLLLDWAGCRAIKKTALQTMKNAGVHVHVMN-RPRFPFFFFHMQKRNHRKITVIDGKIGY 158
Query 126 IGGLNYSAEHMSSYGPEAK----QDYAVRLEGPIVEDILQF---ELENLPGQSAARRWWR 178
IGG N + E++ G +AK +DY +R+ G V D+ +L+ G W
Sbjct 159 IGGFNIAEEYL---GKKAKFGNWEDYHLRMIGEGVHDLQTLFASDLKRNTGIELGSDVWP 215
Query 179 RHHKAEENRQPGEAQVLLVWRDNEEHRDDIERHYLKMLTQARREVIIANAYFFPGYRFLH 238
+ Q G + D +E YL + QA+ + + Y+ P
Sbjct 216 K-------LQQGTISHKIYATDGYS----LENIYLANIAQAKNRLTVCTPYYIPSKPLQE 264
Query 239 ALRKAARRGVRIKLIIQGEPDMPIVRVGARLLYNYLVKGGVQVFEYRRRPLHGKVALMDD 298
AL A + GV +++I+ + D P+VR A Y+ L+ G ++ Y + H K ++DD
Sbjct 265 ALINARKNGVSVRIIVPMKSDHPLVREAAFTYYSELLDAGCLIYRYYQGFYHVKALIIDD 324
Query 299 HWATVGSSNLDPLSLSLNLEANVIIHDRHF 328
H + +G++N D SL LN E NV I D F
Sbjct 325 HLSIIGTANFDKRSLFLNEEVNVEIDDEAF 354
>P34001 Uncharacterized protein SMU_988 [Streptococcus mutans
serotype c (strain ATCC 700610 / UA159)]
Length=461
Score = 110 bits (276), Expect = 1e-29
Identities = 94/316 (30%), Positives = 150/316 (47%), Gaps = 9/316 (3%)
Query 7 EGNKIQLLENGEQYYPAVFKAIGEAQERIILETFIWFEDDVGKQLHAALLAAAQRGVKAE 66
+ K+ NG+ + + K + +A++ I LE FI E + ++ + L Q GV+
Sbjct 97 KNTKVTYFPNGQSKFEEMKKQLLKAEKFIFLEYFIIAEGLMWGEILSILEQKVQEGVEVR 156
Query 67 VLLDGYGS-PDLSDEFVNELTAAGVVFRYYDPRPRLFGMRTNVFRRMHRKIVVIDARIAF 125
V+ DG LS ++ L G+ + + P N R HRKI+VID ++AF
Sbjct 157 VMYDGMLELSTLSFDYAKRLEKIGIKAKVFSPITPFVSTYYNY--RDHRKILVIDNKVAF 214
Query 126 IGGLNYSAEHMSSYGPEAK-QDYAVRLEGPIVEDILQFELENLPGQSAARRWWRRHHKAE 184
GG+N + E+++ +D AV LEG E + F L L S + +
Sbjct 215 NGGINLADEYINQIERFGYWKDTAVMLEG---EGVASFTLMFLQMWSTTNKDYEFAPYLT 271
Query 185 ENRQPGEAQVLLV-WRDNE-EHRDDIERHYLKMLTQARREVIIANAYFFPGYRFLHALRK 242
+N A ++ + D+ +H E Y+ +L QAR V I Y HAL+
Sbjct 272 QNFHEIVANGYVIPYSDSPLDHEKVGENVYIDILNQARDYVYIMTPYLILDSEMEHALQF 331
Query 243 AARRGVRIKLIIQGEPDMPIVRVGARLLYNYLVKGGVQVFEYRRRPLHGKVALMDDHWAT 302
AA RGV +K+I+ G PD + A+ + L+ GV+++E+ +H KV + DD A
Sbjct 332 AAERGVDVKIIMPGIPDKKVPFALAKRYFPALLDAGVKIYEFTPGFVHAKVFIADDIKAV 391
Query 303 VGSSNLDPLSLSLNLE 318
VG+ NLD SL + E
Sbjct 392 VGTINLDYRSLYHHFE 407
>P0A6H8 Cardiolipin synthase A [Escherichia coli (strain K12)]
Length=486
Score = 107 bits (268), Expect = 2e-28
Identities = 103/386 (27%), Positives = 167/386 (43%), Gaps = 43/386 (11%)
Query 7 EGNKIQLLENGEQYYPAVFKAIGEAQERIILETFIWFEDDVGKQLHAALLAAAQRGVKAE 66
+GN++QL+ + A+ + I A+ I + +IW + Q+ +L+AAA+RG+
Sbjct 117 KGNQLQLMTESDDVMQALIRDIQLARHNIEMVFYIWQPGGMADQVAESLMAAARRGIHCR 176
Query 67 VLLDGYGS--------PDLSDEFVNELTAAGVVFRYYDPRPRLFGMRTNVFRRMHRKIVV 118
++LD GS P+L E+ A V R+F R ++ R HRK+++
Sbjct 177 LMLDSAGSVAFFRSPWPELMRNAGIEVVEALKVNLM-----RVFLRRMDL--RQHRKMIM 229
Query 119 IDARIAFIGGLNYSAEHMSSYGPEAKQ--DYAVRLEGPIVEDI-----LQFELEN----L 167
ID IA+ G +N Q D R+EGPI + +E+E L
Sbjct 230 IDNYIAYTGSMNMVDPRYFKQDAGVGQWIDLMARMEGPIATAMGIIYSCDWEIETGKRIL 289
Query 168 PGQSAARRWWRRHHKAEENRQPGEAQ----VLLVWRDNEEHRDDIERHYLKMLTQARREV 223
P + N P E + + D I + L AR +
Sbjct 290 PPPP------------DVNIMPFEQASGHTIHTIASGPGFPEDLIHQALLTAAYSAREYL 337
Query 224 IIANAYFFPGYRFLHALRKAARRGVRIKLIIQGEPDMPIVRVGARLLYNYLVKGGVQVFE 283
I+ YF P LHA+ AA+RGV + +I+ + D +V +R + L+ GV++++
Sbjct 338 IMTTPYFVPSDDLLHAICTAAQRGVDVSIILPRKNDSMLVGWASRAFFTELLAAGVKIYQ 397
Query 284 YRRRPLHGKVALMDDHWATVGSSNLDPLSLSLNLEANVIIHDRHFNQTLRDNLNGIIAAD 343
+ LH K L+D + VG+ NLD SL LN E + I D+ F L + I+
Sbjct 398 FEGGLLHTKSVLVDGELSLVGTVNLDMRSLWLNFEITLAIDDKGFGADLAAVQDDYISRS 457
Query 344 CQQVDETMLPKRTWWNLTKSVLAFHF 369
+ +D + KR W L + F
Sbjct 458 -RLLDARLWLKRPLWQRVAERLFYFF 482
>P75919 Cardiolipin synthase C [Escherichia coli (strain K12)]
Length=473
Score = 86.7 bits (213), Expect = 2e-21
Identities = 92/399 (23%), Positives = 150/399 (38%), Gaps = 91/399 (23%)
Query 14 LENGEQYYPAVFKAIGEAQERIILETFIWFEDDVGKQLHAALLAAAQRGVKAEVLLDGYG 73
LE + A ++ A+ + ++ +IW +D G+ L +ALLAAA+RGV+ +LLD
Sbjct 24 LEKSLDAFAARYRLAEMAEHTLDVQYYIWQDDMSGRLLFSALLAAAKRGVRVRLLLDDNN 83
Query 74 SPDLSDEFVNELTAAGVVFRYYDPRPRL-------FGMR-----------TNVFRRMHRK 115
+P L D + R D PR+ F R + + RRMH K
Sbjct 84 TPGLDD-----------ILRLLDSHPRIEVRLFNPFSFRLLRPLGYITDFSRLNRRMHNK 132
Query 116 IVVIDARIAFIGGLNYSAEHMSSYGPEAKQDYAVRLEGPIVEDI---------------L 160
+D + +GG N + + D V GP+VED+ L
Sbjct 133 SFTVDGVVTLVGGRNIGDAYFGAGEEPLFSDLDVMAIGPVVEDVADDFARYWYCKSVSPL 192
Query 161 QFELENLPGQSAAR--------------RWWRRHHKAEENRQPGEAQVLLVWRDNEEHRD 206
Q L+ G+ A R R+ R+ + + + L+W D
Sbjct 193 QQVLDVPEGEMADRIELPASWHNDAMTHRYLRKMESSPFINHLVDGTLPLIWAKTRLLSD 252
Query 207 D-------IERHYL------KMLTQARREVIIANAYFFPGYRFLHALRKAARRGVRIKLI 253
D +RH L ++ + I ++YF P + L + R+GV+I ++
Sbjct 253 DPAKGEGKAKRHSLLPQRLFDIMGSPSERIDIISSYFVPTRAGVAQLLRMVRKGVKIAIL 312
Query 254 IQ--GEPDMPIVRVGARLLYNYLVKGGVQVFEYR------------------RRPLHGKV 293
D+ +V G L++ GV+++E + LH K
Sbjct 313 TNSLAANDVAVVHAGYARWRKKLLRYGVELYELKPTREQSSTLHDRGITGNSGASLHAKT 372
Query 294 ALMDDHWATVGSSNLDPLSLSLNLEANVIIHDRHFNQTL 332
+D +GS N DP S LN E +I Q +
Sbjct 373 FSIDGKTVFIGSFNFDPRSTLLNTEMGFVIESETLAQLI 411
>Q54Z25 Phospholipase D C [Dictyostelium discoideum]
Length=1640
Score = 38.1 bits (87), Expect = 1e-05
Identities = 36/134 (27%), Positives = 55/134 (41%), Gaps = 28/134 (21%)
Query 16 NGEQYYPAVFKAIGEAQERIILETFIWFEDDVG------------KQLHAALLAAAQRGV 63
NG Y+ V+KA+ A I + + W +V +L + L+ A GV
Sbjct 907 NGSTYFKGVYKALKHATSEIYIAGW-WISPNVSLNRTATSKTPDKYRLDSVLMKKASEGV 965
Query 64 KAEVLL-------DGYGSPDLSDEFVNELTAAGVVFRYYDPRPRLFGMRTNVFRRMHRKI 116
K +L+ GS + F V R+ P ++ H+K+
Sbjct 966 KIYILIWDETMIAMDLGSRGVKSFFEKMHRRNIKVIRHPHMLP--------LYWSHHQKV 1017
Query 117 VVIDARIAFIGGLN 130
VV+D RIAFIGGL+
Sbjct 1018 VVVDQRIAFIGGLD 1031
Score = 35.8 bits (81), Expect = 5e-05
Identities = 47/219 (21%), Positives = 84/219 (38%), Gaps = 58/219 (26%)
Query 166 NLPGQSAARRWWRRHHKAEENRQP-------GEAQVLLV-----WRDNEEHRDDIERHYL 213
+LP Q ++ + HH + QP G +V +V W + + I + YL
Sbjct 1285 SLPHQLNNQQQQQHHHHHHHHYQPPLPPQQRGTCKVQIVRSVCGWSAGQVLENSIYKAYL 1344
Query 214 KMLTQARREVIIANAYFF-------PGYRFLHALRKAARRGV------RIKLIIQGEPDM 260
++ ++ + I N +F P + A+ K + V R+ L++ +
Sbjct 1345 NLINLSQHFIYIQNQFFISSVGFTQPNNQIAFAIYKRIEKAVLLNQVFRVILLLPVHCEG 1404
Query 261 PIVRVGARLLYNYLVKG--GVQVFEYRRRP-----------------------------L 289
I V +L+ Y K G++ ++ P +
Sbjct 1405 DIYDVDTQLIIKYTEKSITGIKTELLKKFPEMDIDQYLSINSLRNWDANGDIIFTEQIYV 1464
Query 290 HGKVALMDDHWATVGSSNLDPLSL--SLNLEANVIIHDR 326
H KV ++DD A +GS+N++ SL S + E II DR
Sbjct 1465 HSKVLIVDDKIAIIGSANINDRSLNGSRDSEICAIIEDR 1503
Score = 30.0 bits (66), Expect = 0.003
Identities = 43/179 (24%), Positives = 71/179 (40%), Gaps = 32/179 (18%)
Query 214 KMLTQARREVIIANAYFFPG--------------YRFLHALRKAARRGVRIKLIIQGEP- 258
K L A E+ IA + P YR L K A GV+I ++I E
Sbjct 917 KALKHATSEIYIAGWWISPNVSLNRTATSKTPDKYRLDSVLMKKASEGVKIYILIWDETM 976
Query 259 -DMPIVRVGARLLYNYLVKGGVQVFEY-RRRPL----HGKVALMDDHWATVGSSNL---- 308
M + G + + + + ++V + PL H KV ++D A +G +L
Sbjct 977 IAMDLGSRGVKSFFEKMHRRNIKVIRHPHMLPLYWSHHQKVVVVDQRIAFIGGLDLCFGR 1036
Query 309 ---DPLSLSLNLEANVIIHDRHFNQTLRDNLNGIIAADCQQVDETMLPKRTWWNLTKSV 364
+ + NLE N D + N + +N + DC VD P+ W +++ S+
Sbjct 1037 YDNEYYFVKDNLEINFPGAD-YINSCIAKPVNNL--KDC-LVDRNTQPRMPWHDVSISL 1091
Score = 24.6 bits (52), Expect = 0.14
Identities = 8/19 (42%), Positives = 14/19 (74%), Gaps = 0/19 (0%)
Query 112 MHRKIVVIDARIAFIGGLN 130
+H K++++D +IA IG N
Sbjct 1464 VHSKVLIVDDKIAIIGSAN 1482
Lambda K H a alpha
0.324 0.139 0.432 0.792 4.96
Gapped
Lambda K H a alpha sigma
0.267 0.0410 0.140 1.90 42.6 43.6
Effective search space used: 3659760
Database: 22c80bf13cdfe6e7cf499fe8a5f7e602.SwissProt.fasta
Posted date: May 20, 2024 6:14 AM
Number of letters in database: 11,354
Number of sequences in database: 22
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Neighboring words threshold: 11
Window for multiple hits: 40
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Data ...
