Comparative Genomics

Z0760 / SwissProt Alignments

BLASTP 2.12.0+


Reference: Stephen F. Altschul, Thomas L. Madden, Alejandro A.
Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J.
Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of
protein database search programs", Nucleic Acids Res. 25:3389-3402.


Reference for composition-based statistics: Alejandro A. Schaffer,
L. Aravind, Thomas L. Madden, Sergei Shavirin, John L. Spouge, Yuri
I. Wolf, Eugene V. Koonin, and Stephen F. Altschul (2001),
"Improving the accuracy of PSI-BLAST protein database searches with
composition-based statistics and other refinements", Nucleic Acids
Res. 29:2994-3005.



Database: b004fcd38472ba5f7d4e1c445be3ee20.SwissProt.fasta
           17 sequences; 5,163 total letters



Query= Z0760

Length=308
                                                                      Score     E
Sequences producing significant alignments:                          (Bits)  Value

P0A9I1 Citrate lyase subunit beta [Escherichia coli (strain K12)]     580     0.0   
P0A9I2 Citrate lyase subunit beta [Escherichia coli O6:H1 (strain...  580     0.0   
P44460 Citrate lyase subunit beta [Haemophilus influenzae (strain...  436     4e-159
P17725 Citrate lyase subunit beta [Klebsiella pneumoniae]             367     6e-132
O53078 Citrate lyase subunit beta [Leuconostoc mesenteroides subs...  301     1e-105
A4WNM9 (3S)-malyl-CoA thioesterase [Cereibacter sphaeroides (stra...  158     5e-50 
B9KNB6 (3S)-malyl-CoA thioesterase [Cereibacter sphaeroides (stra...  153     4e-48 
D3JV05 (3S)-malyl-CoA thioesterase [Cereibacter sphaeroides (stra...  153     5e-48 
A3PN16 (3S)-malyl-CoA thioesterase [Cereibacter sphaeroides (stra...  150     4e-47 
Q9RUZ0 Citrate lyase subunit beta-like protein [Deinococcus radio...  135     4e-41 
D5AR83 L-malyl-CoA/beta-methylmalyl-CoA lyase [Rhodobacter capsul...  130     8e-39 
B6E2X2 L-malyl-CoA/beta-methylmalyl-CoA lyase [Rhodobacter capsul...  130     8e-39 
Q3J5L6 L-malyl-CoA/beta-methylmalyl-CoA lyase [Cereibacter sphaer...  122     4e-36 
Q8R4N0 Citramalyl-CoA lyase, mitochondrial [Mus musculus]             110     3e-31 
Q8N0X4 Citramalyl-CoA lyase, mitochondrial [Homo sapiens]             109     7e-31 
P9WPE1 Citrate lyase subunit beta-like protein [Mycobacterium tub...  105     7e-30 
S5N020 Malyl-CoA/beta-methylmalyl-CoA/citramalyl-CoA lyase [Chlor...  84.3    7e-22 


>P0A9I1 Citrate lyase subunit beta [Escherichia coli (strain K12)]
Length=302

 Score = 580 bits (1495),  Expect = 0.0
 Identities = 301/302 (99%), Positives = 302/302 (100%), Gaps = 0/302 (0%)

Query  6    MISASLQQRKTRTRRSMLFVPGANAAMVSNSFIYPADALMFDLEESVALREKDTARRMVY  65
            MISASLQQRKTRTRRSMLFVPGANAAMVSNSFIYPADALMFDLE+SVALREKDTARRMVY
Sbjct  1    MISASLQQRKTRTRRSMLFVPGANAAMVSNSFIYPADALMFDLEDSVALREKDTARRMVY  60

Query  66   HALQHPLYRDIETIVRVNALDSEWGVNDLEAVVRGGADVVRLPKTDTAQDVLDIEKEILR  125
            HALQHPLYRDIETIVRVNALDSEWGVNDLEAVVRGGADVVRLPKTDTAQDVLDIEKEILR
Sbjct  61   HALQHPLYRDIETIVRVNALDSEWGVNDLEAVVRGGADVVRLPKTDTAQDVLDIEKEILR  120

Query  126  IEKACGREPGSTGLLAAIESPLGITRAVEIAHASERLIGIALGAEDYVRNLRTERSPEGT  185
            IEKACGREPGSTGLLAAIESPLGITRAVEIAHASERLIGIALGAEDYVRNLRTERSPEGT
Sbjct  121  IEKACGREPGSTGLLAAIESPLGITRAVEIAHASERLIGIALGAEDYVRNLRTERSPEGT  180

Query  186  ELLFARCSILQAARSAGIQAFDTVYSDANNEAGFLQEAAHIKQLGFDGKSLINPRQIDLL  245
            ELLFARCSILQAARSAGIQAFDTVYSDANNEAGFLQEAAHIKQLGFDGKSLINPRQIDLL
Sbjct  181  ELLFARCSILQAARSAGIQAFDTVYSDANNEAGFLQEAAHIKQLGFDGKSLINPRQIDLL  240

Query  246  HNLYAPTQKEVDHARRVVEAAEAAAREGLGVVSLNGKMVDGPVIDRARLVLSRAELSGIR  305
            HNLYAPTQKEVDHARRVVEAAEAAAREGLGVVSLNGKMVDGPVIDRARLVLSRAELSGIR
Sbjct  241  HNLYAPTQKEVDHARRVVEAAEAAAREGLGVVSLNGKMVDGPVIDRARLVLSRAELSGIR  300

Query  306  EE  307
            EE
Sbjct  301  EE  302


>P0A9I2 Citrate lyase subunit beta [Escherichia coli O6:H1 (strain 
CFT073 / ATCC 700928 / UPEC)]
Length=302

 Score = 580 bits (1495),  Expect = 0.0
 Identities = 301/302 (99%), Positives = 302/302 (100%), Gaps = 0/302 (0%)

Query  6    MISASLQQRKTRTRRSMLFVPGANAAMVSNSFIYPADALMFDLEESVALREKDTARRMVY  65
            MISASLQQRKTRTRRSMLFVPGANAAMVSNSFIYPADALMFDLE+SVALREKDTARRMVY
Sbjct  1    MISASLQQRKTRTRRSMLFVPGANAAMVSNSFIYPADALMFDLEDSVALREKDTARRMVY  60

Query  66   HALQHPLYRDIETIVRVNALDSEWGVNDLEAVVRGGADVVRLPKTDTAQDVLDIEKEILR  125
            HALQHPLYRDIETIVRVNALDSEWGVNDLEAVVRGGADVVRLPKTDTAQDVLDIEKEILR
Sbjct  61   HALQHPLYRDIETIVRVNALDSEWGVNDLEAVVRGGADVVRLPKTDTAQDVLDIEKEILR  120

Query  126  IEKACGREPGSTGLLAAIESPLGITRAVEIAHASERLIGIALGAEDYVRNLRTERSPEGT  185
            IEKACGREPGSTGLLAAIESPLGITRAVEIAHASERLIGIALGAEDYVRNLRTERSPEGT
Sbjct  121  IEKACGREPGSTGLLAAIESPLGITRAVEIAHASERLIGIALGAEDYVRNLRTERSPEGT  180

Query  186  ELLFARCSILQAARSAGIQAFDTVYSDANNEAGFLQEAAHIKQLGFDGKSLINPRQIDLL  245
            ELLFARCSILQAARSAGIQAFDTVYSDANNEAGFLQEAAHIKQLGFDGKSLINPRQIDLL
Sbjct  181  ELLFARCSILQAARSAGIQAFDTVYSDANNEAGFLQEAAHIKQLGFDGKSLINPRQIDLL  240

Query  246  HNLYAPTQKEVDHARRVVEAAEAAAREGLGVVSLNGKMVDGPVIDRARLVLSRAELSGIR  305
            HNLYAPTQKEVDHARRVVEAAEAAAREGLGVVSLNGKMVDGPVIDRARLVLSRAELSGIR
Sbjct  241  HNLYAPTQKEVDHARRVVEAAEAAAREGLGVVSLNGKMVDGPVIDRARLVLSRAELSGIR  300

Query  306  EE  307
            EE
Sbjct  301  EE  302


>P44460 Citrate lyase subunit beta [Haemophilus influenzae (strain 
ATCC 51907 / DSM 11121 / KW20 / Rd)]
Length=291

 Score = 436 bits (1122),  Expect = 4e-159
 Identities = 221/291 (76%), Positives = 262/291 (90%), Gaps = 1/291 (0%)

Query  17   RTRRSMLFVPGANAAMVSNSFIYPADALMFDLEESVALREKDTARRMVYHALQHPLYRDI  76
            + RRSMLFVPG+NAAM+SNSFIY  D++MFDLE++VAL+EKD+AR +V HALQHPLY++I
Sbjct  2    KLRRSMLFVPGSNAAMLSNSFIYKPDSIMFDLEDAVALKEKDSARLLVAHALQHPLYKEI  61

Query  77   ETIVRVNALDSEWGVNDLEAVVRGGADVVRLPKTDTAQDVLDIEKEILRIEKACGREPGS  136
            ET+VRVN LDSE+G+ DL +VVR G DVVR+PKT++AQDVLD++  I  IEKACGRE GS
Sbjct  62   ETVVRVNPLDSEFGLLDLNSVVRAGVDVVRMPKTESAQDVLDMDHAITEIEKACGREAGS  121

Query  137  TGLLAAIESPLGITRAVEIAHASERLIGIALGAEDYVRNLRTERSPEGTELLFARCSILQ  196
            T +LAAIESPLGIT+A +IA AS+RLIGIALGAEDYVRNL+TERSPEG ELLFARCSILQ
Sbjct  122  TKMLAAIESPLGITQANQIAFASKRLIGIALGAEDYVRNLKTERSPEGIELLFARCSILQ  181

Query  197  AARSAGIQAFDTVYSDANNEAGFLQEAAHIKQLGFDGKSLINPRQIDLLHNLYAPTQKEV  256
            AAR+AGIQAFDTVYS+ANNE GFL+EAA IKQLGFDGKSLINPRQI+LLHNL+APTQK+V
Sbjct  182  AARAAGIQAFDTVYSNANNEEGFLKEAALIKQLGFDGKSLINPRQIELLHNLFAPTQKDV  241

Query  257  DHARRVVEAAEAAAREGLGVVSLNGKMVDGPVIDRARLVLSRAELSGIREE  307
            + A+R++EAA  A R+G GVVSLNGKM+D P+IDRA+LVL RA+ SGIREE
Sbjct  242  EQAKRIIEAAVEAERQGAGVVSLNGKMIDAPIIDRAKLVLERAK-SGIREE  291


>P17725 Citrate lyase subunit beta [Klebsiella pneumoniae]
Length=289

 Score = 367 bits (943),  Expect = 6e-132
 Identities = 187/290 (64%), Positives = 232/290 (80%), Gaps = 2/290 (1%)

Query  17   RTRRSMLFVPGANAAMVSNSFIYPADALMFDLEESVALREKDTARRMVYHALQHPLYRDI  76
            + RRSMLF+PGANAAM+S SF+Y ADA+MFDLE++V+LREKDTAR +VY ALQHPLY+DI
Sbjct  2    KPRRSMLFIPGANAAMLSTSFVYGADAVMFDLEDAVSLREKDTARLLVYQALQHPLYQDI  61

Query  77   ETIVRVNALDSEWGVNDLEAVVRGGADVVRLPKTDTAQDVLDIEKEILRIEKACGREPGS  136
            ET+VR+N L++ +G+ DLEAVVR G D+VRLPKTD+ +D+ ++E  + RIE+ CGRE GS
Sbjct  62   ETVVRINPLNTPFGLADLEAVVRAGVDMVRLPKTDSKEDIHELEAHVERIERECGREVGS  121

Query  137  TGLLAAIESPLGITRAVEIAHASERLIGIALGAEDYVRNLRTERSPEGTELLFARCSILQ  196
            T L+AAIES LG+  AVEIA AS RL  IAL A DYV ++ T R  +GTEL +ARC++L 
Sbjct  122  TKLMAAIESALGVVNAVEIARASPRLAAIALAAFDYVMDMGTSRG-DGTELFYARCAVLH  180

Query  197  AARSAGIQAFDTVYSDANNEAGFLQEAAHIKQLGFDGKSLINPRQIDLLHNLYAPTQKEV  256
            AAR AGI A+D V+SD NNE GFL EA   K LGF+GKSL+NPRQI+LLH +YAPT+KEV
Sbjct  181  AARVAGIAAYDVVWSDINNEEGFLAEANLAKNLGFNGKSLVNPRQIELLHQVYAPTRKEV  240

Query  257  DHARRVVEAAEAAAREGLGVVSLNGKMVDGPVIDRARLVLSRAELSGIRE  306
            DHA  V+ AAE A   GLGVVSLNGKM+DGP+ID AR V++    SGIR+
Sbjct  241  DHALEVIAAAEEAETRGLGVVSLNGKMIDGPIIDHARKVVA-LSASGIRD  289


>O53078 Citrate lyase subunit beta [Leuconostoc mesenteroides 
subsp. cremoris]
Length=302

 Score = 301 bits (771),  Expect = 1e-105
 Identities = 153/283 (54%), Positives = 215/283 (76%), Gaps = 0/283 (0%)

Query  17   RTRRSMLFVPGANAAMVSNSFIYPADALMFDLEESVALREKDTARRMVYHALQHPLYRDI  76
            R RR+M+FVPG N AMV ++ I+ AD++MFDLE++V+L EKD+AR +VY ALQ   Y   
Sbjct  5    RLRRTMMFVPGNNPAMVKDAGIFGADSIMFDLEDAVSLAEKDSARYLVYEALQTVDYGSS  64

Query  77   ETIVRVNALDSEWGVNDLEAVVRGGADVVRLPKTDTAQDVLDIEKEILRIEKACGREPGS  136
            E +VR+N LD+ +  ND++A+V+ G DV+RLPK +TA  + ++E  I   EK  GR  G+
Sbjct  65   ELVVRINGLDTPFYKNDIKAMVKAGIDVIRLPKVETAAMMHELESLITDAEKEFGRPVGT  124

Query  137  TGLLAAIESPLGITRAVEIAHASERLIGIALGAEDYVRNLRTERSPEGTELLFARCSILQ  196
            T ++AAIES LG+  AVEIA+AS+R+IGIAL AEDY  +++T R P+G ELL+AR  IL 
Sbjct  125  THMMAAIESALGVVNAVEIANASDRMIGIALSAEDYTTDMKTHRYPDGQELLYARNVILH  184

Query  197  AARSAGIQAFDTVYSDANNEAGFLQEAAHIKQLGFDGKSLINPRQIDLLHNLYAPTQKEV  256
            AAR+AGI AFDTV+++ N+E GF +E   I QLGFDGKSLINPRQI++++ +YAPT+KE+
Sbjct  185  AARAAGIAAFDTVFTNLNDEEGFYRETQLIHQLGFDGKSLINPRQIEMVNKVYAPTEKEI  244

Query  257  DHARRVVEAAEAAAREGLGVVSLNGKMVDGPVIDRARLVLSRA  299
            ++A+ V+ A E A ++G GV+S+NG+MVD PV+ RA+ V+  A
Sbjct  245  NNAQNVIAAIEEAKQKGSGVISMNGQMVDRPVVLRAQRVMKLA  287


>A4WNM9 (3S)-malyl-CoA thioesterase [Cereibacter sphaeroides (strain 
ATCC 17025 / ATH 2.4.3)]
Length=285

 Score = 158 bits (400),  Expect = 5e-50
 Identities = 99/281 (35%), Positives = 154/281 (55%), Gaps = 12/281 (4%)

Query  20   RSMLFVPGANAAMVSNSFIYPADALMFDLEESVALREKDTARRMVYHALQHPLYRDIETI  79
            RS+L++PG+    +  +    ADA++FDLE++VA  EK  AR ++   L+   Y     I
Sbjct  9    RSVLYIPGSKERALEKAQGLAADAIIFDLEDAVAHDEKIHARDLLRKTLETADYGRRIRI  68

Query  80   VRVNALDSEWGVNDLEAVVRGGADVVRLPKTDTAQDVLDIEKEILRIEKACGREPGSTGL  139
            VRVN +D+EWG +D+ A     ADV+ +PK  +A DV  +   I  +            L
Sbjct  69   VRVNGMDTEWGRDDVAAFAGSKADVILIPKVSSATDVQAVADLIPDVP-----------L  117

Query  140  LAAIESPLGITRAVEIAHASERLIGIALGAEDYVRNLRTERSPEGTELLFARCSILQAAR  199
             A +E+ LG+  A EIA A  RL G+ +G  D  + L +   P+   L       L AAR
Sbjct  118  WAMMETALGMLNAAEIA-AHPRLTGMVMGTNDLAKELTSRFRPDRLALQTGLGLCLLAAR  176

Query  200  SAGIQAFDTVYSDANNEAGFLQEAAHIKQLGFDGKSLINPRQIDLLHNLYAPTQKEVDHA  259
            + G+   D VY+   +E G   E  H + +GFDGK+LI+P Q+++ + +++P+  E++ A
Sbjct  177  AHGLTIVDGVYNAFKDEDGLRAECEHGRDMGFDGKTLIHPAQLEIANEVFSPSSAEIELA  236

Query  260  RRVVEAAEAAAREGLGVVSLNGKMVDGPVIDRARLVLSRAE  300
             R + A E A R G GV  ++GK+V+   I  AR  L++AE
Sbjct  237  NRQIAAFEEAERHGQGVAVVDGKIVENLHIVTARQTLAKAE  277


>B9KNB6 (3S)-malyl-CoA thioesterase [Cereibacter sphaeroides (strain 
KD131 / KCTC 12085)]
Length=285

 Score = 153 bits (387),  Expect = 4e-48
 Identities = 98/281 (35%), Positives = 150/281 (53%), Gaps = 12/281 (4%)

Query  20   RSMLFVPGANAAMVSNSFIYPADALMFDLEESVALREKDTARRMVYHALQHPLYRDIETI  79
            RS+L++PG+    +  +    ADA++FDLE++VA  EK  ARR++   L+   Y     I
Sbjct  9    RSVLYIPGSKERALEKARGLAADAIIFDLEDAVAHDEKIHARRLLKTTLETADYGHRFRI  68

Query  80   VRVNALDSEWGVNDLEAVVRGGADVVRLPKTDTAQDVLDIEKEILRIEKACGREPGSTGL  139
            VRVN +D+EWG  DLEA     AD + +PK   A D          +E      P    L
Sbjct  69   VRVNGMDTEWGRADLEAFAEAKADAILIPKVSRAAD----------LEAVAALVP-DLPL  117

Query  140  LAAIESPLGITRAVEIAHASERLIGIALGAEDYVRNLRTERSPEGTELLFARCSILQAAR  199
             A +E+  G+  A EIA A  RL G+ +G  D  + L +   P+   +       L AAR
Sbjct  118  WAMMETAQGMLNAAEIA-AHPRLTGMVMGTNDLAKELGSRYRPDRLAMQAGLGLCLLAAR  176

Query  200  SAGIQAFDTVYSDANNEAGFLQEAAHIKQLGFDGKSLINPRQIDLLHNLYAPTQKEVDHA  259
            + G+   D VY+   +E G   E    + +GFDGK+LI+P Q+++ + +++P+  E++ A
Sbjct  177  AHGLTIVDGVYNAFRDEEGLRAECEQGRDMGFDGKTLIHPAQLEIANAVFSPSPAEIELA  236

Query  260  RRVVEAAEAAAREGLGVVSLNGKMVDGPVIDRARLVLSRAE  300
             R + A E A R G GV  ++GK+V+   I  AR  L++AE
Sbjct  237  NRQIAAFEEAERHGQGVAVVDGKIVENLHIVTARQTLAKAE  277


>D3JV05 (3S)-malyl-CoA thioesterase [Cereibacter sphaeroides (strain 
ATCC 17023 / DSM 158 / JCM 6121 / CCUG 31486 / LMG 2827 
/ NBRC 12203 / NCIMB 8253 / ATH 2.4.1.)]
Length=285

 Score = 153 bits (386),  Expect = 5e-48
 Identities = 98/281 (35%), Positives = 150/281 (53%), Gaps = 12/281 (4%)

Query  20   RSMLFVPGANAAMVSNSFIYPADALMFDLEESVALREKDTARRMVYHALQHPLYRDIETI  79
            RS+L++PG+    +  +    ADA++FDLE++VA  EK  ARR++   L+   Y     I
Sbjct  9    RSVLYIPGSKERALEKAQGLAADAIIFDLEDAVAHDEKIHARRLLKTTLETADYGHRFRI  68

Query  80   VRVNALDSEWGVNDLEAVVRGGADVVRLPKTDTAQDVLDIEKEILRIEKACGREPGSTGL  139
            VRVN +D+EWG  DLEA     AD + +PK   A D          +E      P    L
Sbjct  69   VRVNGMDTEWGRADLEAFAEAKADAILIPKVSRAAD----------LEAVAALVP-DLPL  117

Query  140  LAAIESPLGITRAVEIAHASERLIGIALGAEDYVRNLRTERSPEGTELLFARCSILQAAR  199
             A +E+  G+  A EIA A  RL G+ +G  D  + L +   P+   +       L AAR
Sbjct  118  WAMMETAQGMLNAAEIA-AHPRLSGMVMGTNDLAKELGSRYRPDRLAMQAGLGLCLLAAR  176

Query  200  SAGIQAFDTVYSDANNEAGFLQEAAHIKQLGFDGKSLINPRQIDLLHNLYAPTQKEVDHA  259
            + G+   D VY+   +E G   E    + +GFDGK+LI+P Q+++ + +++P+  E++ A
Sbjct  177  AHGLTIVDGVYNAFKDEEGLRAECEQGRDMGFDGKTLIHPAQLEIANAVFSPSPAEIELA  236

Query  260  RRVVEAAEAAAREGLGVVSLNGKMVDGPVIDRARLVLSRAE  300
             R + A E A R G GV  ++GK+V+   I  AR  L++AE
Sbjct  237  NRQIAAFEEAERHGQGVAVVDGKIVENLHIVTARQTLAKAE  277


>A3PN16 (3S)-malyl-CoA thioesterase [Cereibacter sphaeroides (strain 
ATCC 17029 / ATH 2.4.9)]
Length=285

 Score = 150 bits (380),  Expect = 4e-47
 Identities = 97/281 (35%), Positives = 149/281 (53%), Gaps = 12/281 (4%)

Query  20   RSMLFVPGANAAMVSNSFIYPADALMFDLEESVALREKDTARRMVYHALQHPLYRDIETI  79
            RS+L++PG+    +  +    ADA++FDLE++VA  EK  AR ++   L+   Y     I
Sbjct  9    RSVLYIPGSKERALEKAQGLAADAIIFDLEDAVAHDEKIHARALLKTTLETVDYGHRFRI  68

Query  80   VRVNALDSEWGVNDLEAVVRGGADVVRLPKTDTAQDVLDIEKEILRIEKACGREPGSTGL  139
            VRVN +D+EWG  DLEA     AD + +PK   A D          +E      P    L
Sbjct  69   VRVNGMDTEWGRADLEAFAEAKADAILIPKVSRAAD----------LEAVAALVP-DLPL  117

Query  140  LAAIESPLGITRAVEIAHASERLIGIALGAEDYVRNLRTERSPEGTELLFARCSILQAAR  199
             A +E+  G+  A EIA A  RL G+ +G  D  + L +   P+   +       L AAR
Sbjct  118  WAMMETAQGMLNAAEIA-AHPRLTGMVMGTNDLAKELGSRYRPDRLAMQAGLGLCLLAAR  176

Query  200  SAGIQAFDTVYSDANNEAGFLQEAAHIKQLGFDGKSLINPRQIDLLHNLYAPTQKEVDHA  259
            + G+   D VY+   +E G   E    + +GFDGK+LI+P Q+++ + +++P+  E++ A
Sbjct  177  AHGLTIVDGVYNAFKDEEGLRAECEQGRDMGFDGKTLIHPAQLEIANAVFSPSPAEIELA  236

Query  260  RRVVEAAEAAAREGLGVVSLNGKMVDGPVIDRARLVLSRAE  300
             R + A E A R G GV  ++GK+V+   I  AR  L++AE
Sbjct  237  NRQIAAFEEAERHGQGVAVVDGKIVENLHIVTARQTLAKAE  277


>Q9RUZ0 Citrate lyase subunit beta-like protein [Deinococcus radiodurans 
(strain ATCC 13939 / DSM 20539 / JCM 16871 / CCUG 
27074 / LMG 4051 / NBRC 15346 / NCIMB 9279 / VKM B-1422 / R1)]
Length=284

 Score = 135 bits (339),  Expect = 4e-41
 Identities = 95/282 (34%), Positives = 145/282 (51%), Gaps = 13/282 (5%)

Query  20   RSMLFVPGANAAMVSNSFIYPADALMFDLEESV-ALREKDTARRMVYHALQHPLYR---D  75
            RS+LF PG  A +++       DA++ DLE++V    E   A R V H     L      
Sbjct  9    RSVLFAPGNRADLIAKLPRSAPDAVVIDLEDAVPGTAEAKAAARPVAHDAARDLIAAAPH  68

Query  76   IETIVRVNALDSEWGVNDLEAVVRGGADVVRLPKTDTAQDVLDIEKEILRIEKACGREPG  135
            +   VRVNAL S +  +DL  +    + VV +PK       L++  E  ++ +       
Sbjct  69   LAVFVRVNALHSPYFEDDLSVLTPELSGVV-VPK-------LEMGAEARQVAQMLQERSL  120

Query  136  STGLLAAIESPLGITRAVEIAHASERLIGIALGAEDYVRNLRTERSPEGTELLFARCSIL  195
               +LA +E+  G+  A EI    E +     GAEDY  +L  +R+P G E+L+AR  + 
Sbjct  121  PLPILAGLETGAGVWNAREIMEVPE-VAWAYFGAEDYTTDLGGKRTPGGLEVLYARSQVA  179

Query  196  QAARSAGIQAFDTVYSDANNEAGFLQEAAHIKQLGFDGKSLINPRQIDLLHNLYAPTQKE  255
             AAR  G+ A D V +  N+   F  +A   + LG+ GK  I+P Q+ L H  + PT+ +
Sbjct  180  LAARLTGVAALDIVVTALNDPETFRADAEQGRALGYSGKLCIHPAQVALAHEYFGPTEAD  239

Query  256  VDHARRVVEAAEAAAREGLGVVSLNGKMVDGPVIDRARLVLS  297
               AR +++AA AAA+ G G  S  G+MVD P++ +AR +LS
Sbjct  240  RARARALLDAAAAAAQRGHGAFSFEGQMVDEPMLAKARTLLS  281


>D5AR83 L-malyl-CoA/beta-methylmalyl-CoA lyase [Rhodobacter capsulatus 
(strain ATCC BAA-309 / NBRC 16581 / SB1003)]
Length=318

 Score = 130 bits (326),  Expect = 8e-39
 Identities = 93/308 (30%), Positives = 151/308 (49%), Gaps = 21/308 (7%)

Query  17   RTRRSMLFVPGANAAMVSNSFIYPADALMFDLEESVALREKDTARRMVYHALQHPLYRDI  76
            R  R  LF PG+  A+        AD +  DLE+SVA  +K  ARR +  A  +  + + 
Sbjct  12   RLNRCQLFGPGSRPAIFEKMAQSAADVINLDLEDSVAPDDKPQARRNIIEASHNIDWGNK  71

Query  77   ETIVRVNALDSEWGVNDLEAVVRGGA---DVVRLPKTDTAQDVLDIEKEILRIEKACGRE  133
               VR+N LD+ +   D+  ++  G+   D + +PK   A DV  ++  +  IE A GR+
Sbjct  72   YLSVRINGLDTPFWYRDVVELLEDGSERIDQIMIPKVGCAADVYAVDALVTAIEAAKGRK  131

Query  134  PGSTGLLAAIESPLGITRAVEIAHASERLIGIALGAEDYVRNLRTERS-----PEGTELL  188
                 L   IES  GI    EIA AS RL  ++LGA D+  ++    +      E   +L
Sbjct  132  K-RISLEVIIESAAGIAHVEEIAAASPRLQAMSLGAADFAASMGMATTGIGGTQENYYML  190

Query  189  ------------FARCSILQAARSAGIQAFDTVYSDANNEAGFLQEAAHIKQLGFDGKSL  236
                        +A+ +I+ A R+ GI   D  + D +++ GF  +A     LG  GK  
Sbjct  191  HAGVKHWSDPWHWAQAAIVAACRTHGILPVDGPFGDFSDDEGFRAQALRSATLGMVGKWA  250

Query  237  INPRQIDLLHNLYAPTQKEVDHARRVVEAAEAAAREGLGVVSLNGKMVDGPVIDRARLVL  296
            I+P+Q+ L + ++ P+   V  AR ++ A E A  EG G     G++VD   I +A +++
Sbjct  251  IHPKQVALANEVFTPSDAAVAEAREILAAMEKAKAEGAGATVYKGRLVDIASIRQAEVIV  310

Query  297  SRAELSGI  304
             +AE++ +
Sbjct  311  RQAEMAKV  318


>B6E2X2 L-malyl-CoA/beta-methylmalyl-CoA lyase [Rhodobacter capsulatus]
Length=318

 Score = 130 bits (326),  Expect = 8e-39
 Identities = 93/308 (30%), Positives = 151/308 (49%), Gaps = 21/308 (7%)

Query  17   RTRRSMLFVPGANAAMVSNSFIYPADALMFDLEESVALREKDTARRMVYHALQHPLYRDI  76
            R  R  LF PG+  A+        AD +  DLE+SVA  +K  ARR +  A  +  + + 
Sbjct  12   RLNRCQLFGPGSRPAIFEKMAQSAADVINLDLEDSVAPDDKPQARRNIIEASHNIDWGNK  71

Query  77   ETIVRVNALDSEWGVNDLEAVVRGGA---DVVRLPKTDTAQDVLDIEKEILRIEKACGRE  133
               VR+N LD+ +   D+  ++  G+   D + +PK   A DV  ++  +  IE A GR+
Sbjct  72   YLSVRINGLDTPFWYRDVVELLEDGSERIDQIMIPKVGCAADVYAVDALVTAIEAAKGRK  131

Query  134  PGSTGLLAAIESPLGITRAVEIAHASERLIGIALGAEDYVRNLRTERS-----PEGTELL  188
                 L   IES  GI    EIA AS RL  ++LGA D+  ++    +      E   +L
Sbjct  132  K-RISLEVIIESAAGIAHVEEIAAASPRLQAMSLGAADFAASMGMATTGIGGTQENYYML  190

Query  189  ------------FARCSILQAARSAGIQAFDTVYSDANNEAGFLQEAAHIKQLGFDGKSL  236
                        +A+ +I+ A R+ GI   D  + D +++ GF  +A     LG  GK  
Sbjct  191  HAGVKHWSDPWHWAQAAIVAACRTHGILPVDGPFGDFSDDEGFRAQALRSATLGMVGKWA  250

Query  237  INPRQIDLLHNLYAPTQKEVDHARRVVEAAEAAAREGLGVVSLNGKMVDGPVIDRARLVL  296
            I+P+Q+ L + ++ P+   V  AR ++ A E A  EG G     G++VD   I +A +++
Sbjct  251  IHPKQVALANEVFTPSDAAVAEAREILAAMEKAKAEGAGATVYKGRLVDIASIRQAEVIV  310

Query  297  SRAELSGI  304
             +AE++ +
Sbjct  311  RQAEMAKV  318


>Q3J5L6 L-malyl-CoA/beta-methylmalyl-CoA lyase [Cereibacter sphaeroides 
(strain ATCC 17023 / DSM 158 / JCM 6121 / CCUG 31486 
/ LMG 2827 / NBRC 12203 / NCIMB 8253 / ATH 2.4.1.)]
Length=318

 Score = 122 bits (307),  Expect = 4e-36
 Identities = 90/306 (29%), Positives = 151/306 (49%), Gaps = 23/306 (8%)

Query  17   RTRRSMLFVPGANAAMVSNSFIYPADALMFDLEESVALREKDTARRMVYHALQHPLYRDI  76
            R  R  LF PG+  A+        AD +  DLE+SVA  +K  AR  +  A+    +   
Sbjct  12   RPNRCQLFGPGSRPALFEKMAASAADVINLDLEDSVAPDDKAQARANIIEAINGLDWGRK  71

Query  77   ETIVRVNALDSEWGVNDLEAVVRGGAD---VVRLPKTDTAQDVLDIEKEILRIEKACGR-  132
               VR+N LD+ +   D+  ++    D    + +PK   A DV  ++  +  IE+A GR 
Sbjct  72   YLSVRINGLDTPFWYRDVVDLLEQAGDRLDQIMIPKVGCAADVYAVDALVTAIERAKGRT  131

Query  133  EPGSTGLLAAIESPLGITRAVEIAHASERLIGIALGAEDYVRNLRTERS-----PEGTEL  187
            +P S  ++  IES  GI    EIA +S RL  ++LGA D+  ++  + +      E   +
Sbjct  132  KPLSFEVI--IESAAGIAHVEEIAASSPRLQAMSLGAADFAASMGMQTTGIGGTQENYYM  189

Query  188  L------------FARCSILQAARSAGIQAFDTVYSDANNEAGFLQEAAHIKQLGFDGKS  235
            L            +A+ +I+ A R+ GI   D  + D +++ GF  +A     LG  GK 
Sbjct  190  LHDGQKHWSDPWHWAQAAIVAACRTHGILPVDGPFGDFSDDEGFRAQARRSATLGMVGKW  249

Query  236  LINPRQIDLLHNLYAPTQKEVDHARRVVEAAEAAAREGLGVVSLNGKMVDGPVIDRARLV  295
             I+P+Q+ L + ++ P++  V  AR ++ A +AA   G G     G++VD   I +A ++
Sbjct  250  AIHPKQVALANEVFTPSETAVTEAREILAAMDAAKARGEGATVYKGRLVDIASIKQAEVI  309

Query  296  LSRAEL  301
            + +AE+
Sbjct  310  VRQAEM  315


>Q8R4N0 Citramalyl-CoA lyase, mitochondrial [Mus musculus]
Length=338

 Score = 110 bits (274),  Expect = 3e-31
 Identities = 73/302 (24%), Positives = 147/302 (49%), Gaps = 13/302 (4%)

Query  9    ASLQQRKTRTRRSMLFVPGANAAMVSNSFIYPADALMFDLEESVALREKDTARRMVYHAL  68
            +SL   K   RR++L+VPG +   +        D  + D E+ VA  +K+ AR  +   L
Sbjct  33   SSLSNHKYVPRRAVLYVPGNDEKKIRKIPSLKVDCAVLDCEDGVAENKKNEARLRIAKTL  92

Query  69   QHPLYRDIETIVRVNALDSEWGVNDLEAVVRGGA--DVVRLPKTDTAQDVLDI-EKEILR  125
            +       E  VR+N++ S     DLE  ++       + LPK +  +++    +K  L 
Sbjct  93   EDFDLGTTEKCVRINSVSSGLAEVDLETFLQARVLPSSLMLPKVEGPEEIRWFSDKFSLH  152

Query  126  IEKACGREPGSTGLLAAIESPLGITRAVEIAHASER--------LIGIALGAEDYVRNLR  177
            ++     +P    L+  +E+ +G+     +   + +        L  +  G ED+  ++ 
Sbjct  153  LKGRKLEQP--MNLIPFVETAMGLLNFKAVCEETLKTGPQVGLCLDAVVFGGEDFRASIG  210

Query  178  TERSPEGTELLFARCSILQAARSAGIQAFDTVYSDANNEAGFLQEAAHIKQLGFDGKSLI  237
               + +  ++L+AR  ++  A++ G+QA D VY D  +E G L+++     +GF GK +I
Sbjct  211  ATSNKDTQDILYARQKVVVTAKAFGLQAIDLVYIDFRDEDGLLRQSREAAAMGFTGKQVI  270

Query  238  NPRQIDLLHNLYAPTQKEVDHARRVVEAAEAAAREGLGVVSLNGKMVDGPVIDRARLVLS  297
            +P QI ++   + PT +++  A  ++ A +   + G G  +  G M+D P++ +A+ +++
Sbjct  271  HPNQIAVVQEQFTPTPEKIQWAEELIAAFKEHQQLGKGAFTFRGSMIDMPLLKQAQNIVT  330

Query  298  RA  299
             A
Sbjct  331  LA  332


>Q8N0X4 Citramalyl-CoA lyase, mitochondrial [Homo sapiens]
Length=340

 Score = 109 bits (272),  Expect = 7e-31
 Identities = 74/302 (25%), Positives = 147/302 (49%), Gaps = 13/302 (4%)

Query  9    ASLQQRKTRTRRSMLFVPGANAAMVSNSFIYPADALMFDLEESVALREKDTARRMVYHAL  68
            +S    K   RR++L+VPG +   +        D  + D E+ VA  +K+ AR  +   L
Sbjct  35   SSSSHHKYIPRRAVLYVPGNDEKKIKKIPSLNVDCAVLDCEDGVAANKKNEARLRIVKTL  94

Query  69   QHPLYRDIETIVRVNALDSEWGVNDLEAVVRGGA--DVVRLPKTDTAQDVLDI-EKEILR  125
            +       E  VRVN++ S     DLE +++       + LPK ++ +++    +K    
Sbjct  95   EDIDLGPTEKCVRVNSVSSGLAEEDLETLLQSRVLPSSLMLPKVESPEEIQWFADKFSFH  154

Query  126  IEKACGREPGSTGLLAAIESPLGITRAVEIAHASER--------LIGIALGAEDYVRNLR  177
            ++     +P    L+  +E+ +G+     +   + +        L  +  G ED+  ++ 
Sbjct  155  LKGRKLEQP--MNLIPFVETAMGLLNFKAVCEETLKVGPQVGLFLDAVVFGGEDFRASIG  212

Query  178  TERSPEGTELLFARCSILQAARSAGIQAFDTVYSDANNEAGFLQEAAHIKQLGFDGKSLI  237
               S E  ++L+AR  I+  A++ G+QA D VY D  + AG L+++     +GF GK +I
Sbjct  213  ATSSKETLDILYARQKIVVIAKAFGLQAIDLVYIDFRDGAGLLRQSREGAAMGFTGKQVI  272

Query  238  NPRQIDLLHNLYAPTQKEVDHARRVVEAAEAAAREGLGVVSLNGKMVDGPVIDRARLVLS  297
            +P QI ++   ++P+ +++  A  ++ A +   + G G  +  G M+D P++ +A+  ++
Sbjct  273  HPNQIAVVQEQFSPSPEKIKWAEELIAAFKEHQQLGKGAFTFQGSMIDMPLLKQAQNTVT  332

Query  298  RA  299
             A
Sbjct  333  LA  334


>P9WPE1 Citrate lyase subunit beta-like protein [Mycobacterium 
tuberculosis (strain ATCC 25618 / H37Rv)]
Length=273

 Score = 105 bits (261),  Expect = 7e-30
 Identities = 84/264 (32%), Positives = 129/264 (49%), Gaps = 29/264 (11%)

Query  41   ADALMFDLEESVALREKDTARRMVYHALQHPLYRDIETIVRVNALDSEWGVNDLEAVVRG  100
            AD ++ DLE+ VA  +K  AR    +AL+        T+VR+NA  +     DLEA+   
Sbjct  28   ADVVILDLEDGVAEAQKPAAR----NALRDTPLDPERTVVRINAGGTADQARDLEALAGT  83

Query  101  GADVVRLPKTDTAQDVLDIEKEILRIEKACGREPGSTGLLAAIESPLGITRAVEIAHASE  160
                V LPK ++A  V+++                   ++A +E+  G   A EIA A++
Sbjct  84   AYTTVMLPKAESAAQVIELAPR---------------DVIALVETARGAVCAAEIA-AAD  127

Query  161  RLIGIALGAEDYVRNL--RTERSPEGTELLFAR---CSILQAARSAGIQAFDTVYSDANN  215
              +G+  GAED +  L   + R  +G     AR    +IL AA + G  A D V+ D  +
Sbjct  128  PTVGMMWGAEDLIATLGGSSSRRADGAYRDVARHVRSTILLAASAFGRLALDAVHLDILD  187

Query  216  EAGFLQEAAHIKQLGFDGKSLINPRQIDLLHNLYAPTQKEVDHARRVVEAAEAAAREGLG  275
              G  +EA     +GFD    I+P QI ++   Y P+ +++  ARRV+    AA+R   G
Sbjct  188  VEGLQEEARDAAAVGFDVTVCIHPSQIPVVRKAYRPSHEKLAWARRVL----AASRSERG  243

Query  276  VVSLNGKMVDGPVIDRARLVLSRA  299
              +  G+MVD PV+  A  +L RA
Sbjct  244  AFAFEGQMVDSPVLTHAETMLRRA  267


>S5N020 Malyl-CoA/beta-methylmalyl-CoA/citramalyl-CoA lyase [Chloroflexus 
aurantiacus]
Length=348

 Score = 84.3 bits (207),  Expect = 7e-22
 Identities = 73/289 (25%), Positives = 130/289 (45%), Gaps = 36/289 (12%)

Query  42   DALMFDLEESVALREKDTARRMVYHALQHPLYRDIETIVRVNALDSEWGVNDLE---AVV  98
            D L  +LE+++ +  K+ AR      ++   + D    VRVNAL+S W ++D+    A V
Sbjct  53   DVLCGNLEDAIPMDAKEAARNGFIEVVKATDFGDTALWVRVNALNSPWVLDDIAEIVAAV  112

Query  99   RGGADVVRLPKTDTAQDVLDIEKEILRIEKACGREPGSTGLL--AAIESPLGITRAVEIA  156
                DV+ +PK +   D+  +++ +  +E    R      +L  A +E+  G+    EIA
Sbjct  113  GNKLDVIMIPKVEGPWDIHFVDQYLALLE---ARHQIKKPILIHALLETAQGMVNLEEIA  169

Query  157  HASERLIGIALGAEDYV--RNLRTERSPEGTELL----------------------FARC  192
             AS R+ G +LG  D    R ++T R   G                          +   
Sbjct  170  GASPRMHGFSLGPADLAASRGMKTTRVGGGHPFYGVLADPQEGQAERPFYQQDLWHYTIA  229

Query  193  SILQAARSAGIQAFDTVYSDANNEAGFLQEAAHIKQLGFDGKSLINPRQIDLLHNLYAPT  252
             ++  A + G++AF   + D  +EA    +  +   LG  G   + P QI +   +++P 
Sbjct  230  RMVDVAVAHGLRAFYGPFGDIKDEAACEAQFRNAFLLGCTGAWSLAPNQIPIAKRVFSPD  289

Query  253  QKEVDHARRVVEAAEAAAREGLGVVSLNGKMVDGPVIDRARLVLSRAEL  301
              EV  A+R++EA      +G GV  ++GKM D     +A++++  A +
Sbjct  290  VNEVLFAKRILEAMP----DGSGVAMIDGKMQDDATWKQAKVIVDLARM  334



Lambda      K        H        a         alpha
   0.320    0.135    0.378    0.792     4.96 

Gapped
Lambda      K        H        a         alpha    sigma
   0.267   0.0410    0.140     1.90     42.6     43.6 

Effective search space used: 1147822


  Database: b004fcd38472ba5f7d4e1c445be3ee20.SwissProt.fasta
    Posted date:  May 20, 2024  9:37 AM
  Number of letters in database: 5,163
  Number of sequences in database:  17



Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Neighboring words threshold: 11
Window for multiple hits: 40