BLASTP 2.12.0+
Reference: Stephen F. Altschul, Thomas L. Madden, Alejandro A.
Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J.
Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of
protein database search programs", Nucleic Acids Res. 25:3389-3402.
Reference for composition-based statistics: Alejandro A. Schaffer,
L. Aravind, Thomas L. Madden, Sergei Shavirin, John L. Spouge, Yuri
I. Wolf, Eugene V. Koonin, and Stephen F. Altschul (2001),
"Improving the accuracy of PSI-BLAST protein database searches with
composition-based statistics and other refinements", Nucleic Acids
Res. 29:2994-3005.
Database: 9d5a5fed76d7f61c6ccdeda53f44ceaa.SwissProt.fasta
14 sequences; 4,858 total letters
Query= Z1022
Length=362
Score E
Sequences producing significant alignments: (Bits) Value
P58409 Hydroxycarboxylate dehydrogenase B [Escherichia coli O157:H7] 743 0.0
P30178 Hydroxycarboxylate dehydrogenase B [Escherichia coli (stra... 736 0.0
Q07251 L-lactate dehydrogenase [Cupriavidus necator (strain ATCC ... 195 6e-63
Q58820 L-sulfolactate dehydrogenase [Methanocaldococcus jannaschi... 179 7e-57
Q9V0D5 Malate dehydrogenase [Pyrococcus abyssi (strain GE5 / Orsay)] 175 4e-55
O27273 L-sulfolactate dehydrogenase [Methanothermobacter thermaut... 171 1e-53
P16142 Malate/(S)-sulfolactate dehydrogenase [Methanothermus ferv... 168 1e-52
O59028 Malate dehydrogenase [Pyrococcus horikoshii (strain ATCC 7... 165 3e-51
Q5FB93 Delta(1)-pyrroline-2-carboxylate/Delta(1)-piperideine-2-ca... 147 2e-44
P77555 Ureidoglycolate dehydrogenase (NAD(+)) [Escherichia coli (... 140 9e-42
Q4U331 Delta(1)-pyrroline-2-carboxylate/Delta(1)-piperideine-2-ca... 132 8e-39
D7A0Y0 Delta(1)-pyrroline-2-carboxylate reductase [Starkeya novel... 125 3e-36
Q1QWN5 (2R)-3-sulfolactate dehydrogenase (NADP(+)) [Chromohalobac... 119 2e-34
Q9I492 Delta(1)-pyrroline-2-carboxylate/Delta(1)-piperideine-2-ca... 118 7e-34
>P58409 Hydroxycarboxylate dehydrogenase B [Escherichia coli O157:H7]
Length=361
Score = 743 bits (1917), Expect = 0.0
Identities = 361/361 (100%), Positives = 361/361 (100%), Gaps = 0/361 (0%)
Query 1 MESGHRFDAQTLHSFIQAVFRQMGSEEQEAKLVADHLIAANLAGHDSHGIGMIPSYVRSW 60
MESGHRFDAQTLHSFIQAVFRQMGSEEQEAKLVADHLIAANLAGHDSHGIGMIPSYVRSW
Sbjct 1 MESGHRFDAQTLHSFIQAVFRQMGSEEQEAKLVADHLIAANLAGHDSHGIGMIPSYVRSW 60
Query 61 SQGHLQINHHAKIVKEAGAAVTLDGDRAFGQVAAHEAMALGIEKAHQHGIAAVALHNSHH 120
SQGHLQINHHAKIVKEAGAAVTLDGDRAFGQVAAHEAMALGIEKAHQHGIAAVALHNSHH
Sbjct 61 SQGHLQINHHAKIVKEAGAAVTLDGDRAFGQVAAHEAMALGIEKAHQHGIAAVALHNSHH 120
Query 121 IGRIGYWAEQCAAAGFVSIHFVSVVGIPMVAPFHGRDSRFGTNPFCVVFPRKDDFPLLLD 180
IGRIGYWAEQCAAAGFVSIHFVSVVGIPMVAPFHGRDSRFGTNPFCVVFPRKDDFPLLLD
Sbjct 121 IGRIGYWAEQCAAAGFVSIHFVSVVGIPMVAPFHGRDSRFGTNPFCVVFPRKDDFPLLLD 180
Query 181 YATSAIAFGKTRVAWHKGVPVPPGCLIDVNGVPTTNPAVMQESPLGSLLTFAEHKGYALA 240
YATSAIAFGKTRVAWHKGVPVPPGCLIDVNGVPTTNPAVMQESPLGSLLTFAEHKGYALA
Sbjct 181 YATSAIAFGKTRVAWHKGVPVPPGCLIDVNGVPTTNPAVMQESPLGSLLTFAEHKGYALA 240
Query 241 AMCEILGGALSGGKTTHQETLQTSPDAILNCMTTIIINPELFGAPDCSAQTEAFAEWVKA 300
AMCEILGGALSGGKTTHQETLQTSPDAILNCMTTIIINPELFGAPDCSAQTEAFAEWVKA
Sbjct 241 AMCEILGGALSGGKTTHQETLQTSPDAILNCMTTIIINPELFGAPDCSAQTEAFAEWVKA 300
Query 301 SPHDDDKPILLPGEWEVNTRRERQEQGIPLDAGSWQAICDAARQIGMPEETLQAFCQQLA 360
SPHDDDKPILLPGEWEVNTRRERQEQGIPLDAGSWQAICDAARQIGMPEETLQAFCQQLA
Sbjct 301 SPHDDDKPILLPGEWEVNTRRERQEQGIPLDAGSWQAICDAARQIGMPEETLQAFCQQLA 360
Query 361 S 361
S
Sbjct 361 S 361
>P30178 Hydroxycarboxylate dehydrogenase B [Escherichia coli (strain
K12)]
Length=361
Score = 736 bits (1900), Expect = 0.0
Identities = 357/361 (99%), Positives = 360/361 (99%), Gaps = 0/361 (0%)
Query 1 MESGHRFDAQTLHSFIQAVFRQMGSEEQEAKLVADHLIAANLAGHDSHGIGMIPSYVRSW 60
MESGHRFDAQTLHSFIQAVFRQMGSEEQEAKLVADHLIAANLAGHDSHGIGMIPSYVRSW
Sbjct 1 MESGHRFDAQTLHSFIQAVFRQMGSEEQEAKLVADHLIAANLAGHDSHGIGMIPSYVRSW 60
Query 61 SQGHLQINHHAKIVKEAGAAVTLDGDRAFGQVAAHEAMALGIEKAHQHGIAAVALHNSHH 120
SQGHLQINHHAK VKEAGAAVTLDGDRAFGQVAAHEAMALGIEKAHQHGIAAVALHNSHH
Sbjct 61 SQGHLQINHHAKTVKEAGAAVTLDGDRAFGQVAAHEAMALGIEKAHQHGIAAVALHNSHH 120
Query 121 IGRIGYWAEQCAAAGFVSIHFVSVVGIPMVAPFHGRDSRFGTNPFCVVFPRKDDFPLLLD 180
IGRIGYWAEQCAAAGFVSIHFVSVVGIPMVAPFHGRDSRFGTNPFCVVFPRKD+FPLLLD
Sbjct 121 IGRIGYWAEQCAAAGFVSIHFVSVVGIPMVAPFHGRDSRFGTNPFCVVFPRKDNFPLLLD 180
Query 181 YATSAIAFGKTRVAWHKGVPVPPGCLIDVNGVPTTNPAVMQESPLGSLLTFAEHKGYALA 240
YATSAIAFGKTRVAWHKGVPVPPGCLIDVNGVPTTNPAVMQESPLGSLLTFAEHKGYALA
Sbjct 181 YATSAIAFGKTRVAWHKGVPVPPGCLIDVNGVPTTNPAVMQESPLGSLLTFAEHKGYALA 240
Query 241 AMCEILGGALSGGKTTHQETLQTSPDAILNCMTTIIINPELFGAPDCSAQTEAFAEWVKA 300
AMCEILGGALSGGKTTHQETLQTSPDAILNCMTTIIINPELFGAPDC+AQTEAFAEWVKA
Sbjct 241 AMCEILGGALSGGKTTHQETLQTSPDAILNCMTTIIINPELFGAPDCNAQTEAFAEWVKA 300
Query 301 SPHDDDKPILLPGEWEVNTRRERQEQGIPLDAGSWQAICDAARQIGMPEETLQAFCQQLA 360
SPHDDDKPILLPGEWEVNTRRERQ+QGIPLDAGSWQAICDAARQIGMPEETLQAFCQQLA
Sbjct 301 SPHDDDKPILLPGEWEVNTRRERQKQGIPLDAGSWQAICDAARQIGMPEETLQAFCQQLA 360
Query 361 S 361
S
Sbjct 361 S 361
>Q07251 L-lactate dehydrogenase [Cupriavidus necator (strain ATCC
17699 / DSM 428 / KCTC 22496 / NCIMB 10442 / H16 / Stanier
337)]
Length=349
Score = 195 bits (496), Expect = 6e-63
Identities = 119/324 (37%), Positives = 174/324 (54%), Gaps = 9/324 (3%)
Query 33 VADHLIAANLAGHDSHGIGMIPSYVRSWSQGH-LQINHHAKIVKEAGAAVTLDGDRAFGQ 91
VA+HL+ ++ G+ SHG+ ++P+Y R+ GH + AK V + G + DGD FGQ
Sbjct 29 VAEHLVESDRCGYISHGLSILPNY-RTALDGHSVNPQGRAKCVLDQGTLMVFDGDGGFGQ 87
Query 92 VAAHEAMALGIEKAHQHGIAAVALHNSHHIGRIGYWAEQCAAAGFVSIHFVSVVG-IPMV 150
M IE+ QHG V L SHH+GR+G++ E AAAGFV + F +V+ P+V
Sbjct 88 HVGKSVMQAAIERVRQHGHCIVTLRRSHHLGRMGHYGEMAAAAGFVLLSFTNVINRAPVV 147
Query 151 APFHGRDSRFGTNPFCVVFPRKDDF-PLLLDYATSAIAFGKTRVAWHKGVPVPPGCLIDV 209
APF GR +R TNP C P + PL++D ATSAIA K RV KG P P G +I
Sbjct 148 APFGGRVARLTTNPLCFAGPMPNGRPPLVVDIATSAIAINKARVLAEKGEPAPEGSIIGA 207
Query 210 NGVPTTNPAVMQESPLGSLLTFAEHKGYALAAMCEILGGALSGGKTTHQETLQTSPDAIL 269
+G PTT+ + M G+LL F HKGYAL + E+L G LSGG T + +
Sbjct 208 DGNPTTDASTMFGEHPGALLPFGGHKGYALGVVAELLAGVLSGGGTIQPDNPRGG--VAT 265
Query 270 NCMTTIIINPEL-FGAPDCSAQTEAFAEWVKASPHDDD-KPILLPGEWEVNTRRERQEQG 327
N + +++NP L G SA+ EAF ++ +P + PGE+E R + +
Sbjct 266 NNLFAVLLNPALDLGLDWQSAEVEAFVRYLHDTPPAPGVDRVQYPGEYEAANRAQASDT- 324
Query 328 IPLDAGSWQAICDAARQIGMPEET 351
+ ++ W+ + A+ + + T
Sbjct 325 LNINPAIWRNLERLAQSLNVAVPT 348
>Q58820 L-sulfolactate dehydrogenase [Methanocaldococcus jannaschii
(strain ATCC 43067 / DSM 2661 / JAL-1 / JCM 10045 / NBRC
100440)]
Length=344
Score = 179 bits (455), Expect = 7e-57
Identities = 115/336 (34%), Positives = 172/336 (51%), Gaps = 20/336 (6%)
Query 19 VFRQMGSEEQEAKLVADHLIAANLAGHDSHGIGMIPSYVRSWSQGHLQINHHAKIVKEAG 78
V ++ G E++AK+ AD + A+L G SHGIG P Y+ + G++ KIVKE+
Sbjct 15 VLKKFGVPEEDAKITADVFVDADLKGFTSHGIGRFPQYITALKLGNINPKPDIKIVKESP 74
Query 79 AAVTLDGDRAFGQVAAHEAMALGIEKAHQHGIAAVALHNSHHIGRIGYWAEQCAAAGFVS 138
A +DGD GQV +AM L I+KA G+ VA N++H G GY++E +
Sbjct 75 ATAVIDGDLGLGQVVGKKAMELAIKKAKNVGVGVVATRNANHFGIAGYYSELAMNQDMIG 134
Query 139 IHFVSVVGIPMVAPFHGRDSRFGTNPFCVVFPRKDDFPLLLDYATSAIAFGKTRVAWHKG 198
I + P +APF G++ GTNP + F + + + LD AT++IA GK A K
Sbjct 135 ITITNTE--PAMAPFGGKEKILGTNPIAIAF-KGNKYKFSLDMATASIARGKILEALRKK 191
Query 199 VPVPPGCLIDVNGVPTTNPAVMQESPLGSLLTFAEHKGYALAAMCEIL---GGALSGGK- 254
+ +P GC +D +G PTT+PA E G +L F KGY LA E+L GGA G K
Sbjct 192 IKIPEGCAVDKDGKPTTDPAKALE---GCILPFGGPKGYGLALAIEMLSAIGGAEVGTKV 248
Query 255 --TTHQETLQTSPDAILNCMTTIIINPELF-GAPDCSAQTEAFAEWVKASPHDDDKPILL 311
T + E T D I INPE F G + + + + +K S + IL+
Sbjct 249 KGTANPEERCTKGDLF------IAINPEFFMGKEEFKRKVDELLDEIKNSEPAEGFEILI 302
Query 312 PGEWEVNTRRERQEQGIPLDAGSWQAICDAARQIGM 347
PGE E + +R++ G +D + + + ++G+
Sbjct 303 PGEIEERNKMKRKD-GFEIDKNLYNQLKEICNELGL 337
>Q9V0D5 Malate dehydrogenase [Pyrococcus abyssi (strain GE5 /
Orsay)]
Length=362
Score = 175 bits (444), Expect = 4e-55
Identities = 123/349 (35%), Positives = 173/349 (50%), Gaps = 11/349 (3%)
Query 6 RFDAQTLHSFIQAVFRQMGSEEQEAKLVADHLIAANLAGHDSHGIGMIPSYVRSWSQGHL 65
R L SF+ V ++G+ E++AK+VAD+LI A+L G +SHG+ + YV G +
Sbjct 13 RIPKDELFSFVVRVLTKLGTPEEDAKIVADNLIMADLRGIESHGVQRLKRYVDGILSGGI 72
Query 66 QINHHAKIVKEAGAAVTLDGDRAFGQVAAHEAMALGIEKAHQHGIAAVALHNSHHIGRIG 125
++ KI++E + LDGD FGQV ++AM L IEKA + GI VA+ NS+H G G
Sbjct 73 NLHPRIKIIREGPSYALLDGDEGFGQVVGYKAMKLAIEKARKTGIGIVAVRNSNHYGIAG 132
Query 126 YWAEQCAAAGFVSIHFVSVVGIPMVAPFHGRDSRFGTNPFCVVFPRKDDFPLLLDYATSA 185
Y+A A G + I + P+VAP G + GTNP + P K P LLD ATS
Sbjct 133 YYALMAAEEGMIGISMTN--SRPLVAPTGGVERILGTNPIALAAPTKGK-PFLLDMATSV 189
Query 186 IAFGKTRVAWHKGVPVPPGCLIDVNGVPTTN-PAVMQESPLGSLLTFAE----HKGYALA 240
+ GK V KG +P G I+ G T + V L L F E HKGY L+
Sbjct 190 VPIGKLEVYRRKGEEIPEGWAINSKGEITRSVEEVFNGGSLLPLGGFGELLGGHKGYGLS 249
Query 241 AMCEILGGALSGGKTTHQETLQTSPDAILNCMTTIIINPELFGAPD--CSAQTEAFAEWV 298
M +IL G LSGG T + T+ C + IN E F + +E E
Sbjct 250 LMVDILSGILSGG-TWSKHVKNTNEKNSNVCHFFMAINIEHFTPLEEFKGRMSEMINEIK 308
Query 299 KASPHDDDKPILLPGEWEVNTRRERQEQGIPLDAGSWQAICDAARQIGM 347
+ H D + I + GE T R + GIP+ + + AR++G+
Sbjct 309 NSRKHPDFERIWIHGEKGFLTMETRLKLGIPIYKKVLDELNEIARRVGV 357
>O27273 L-sulfolactate dehydrogenase [Methanothermobacter thermautotrophicus
(strain ATCC 29096 / DSM 1053 / JCM 10044 / NBRC
100330 / Delta H)]
Length=341
Score = 171 bits (433), Expect = 1e-53
Identities = 111/337 (33%), Positives = 169/337 (50%), Gaps = 23/337 (7%)
Query 16 IQAVFRQMGSEEQEAKLVADHLIAANLAGHDSHGIGMIPSYVRSWSQGHLQINHHAKIVK 75
I+ + M E+ + +VAD + A+L G SHGIG P YV G ++ + I +
Sbjct 12 IKEILTAMNVPEESSDIVADVTLDADLKGFSSHGIGRFPQYVDGLRHGTIRADGDITIER 71
Query 76 EAGAAVTLDGDRAFGQVAAHEAMALGIEKAHQHGIAAVALHNSHHIGRIGYWAEQCAAAG 135
E + ++G+ FG V A+ AM L IEKA G+ V +H+S+H G GY+++
Sbjct 72 ETESTALINGNHIFGHVVAYRAMELAIEKARNTGVGLVGVHDSNHFGVAGYYSDMAVMND 131
Query 136 FVSIHFVSVVGIPMVAPFHGRDSRFGTNPFCVVFPRKDDFPLLLDYATSAIAFGKTRVAW 195
+ + + P VAP GR GTNP + P + + + +D ATSA A GK A
Sbjct 132 MIGVVIANTE--PAVAPIGGRKPILGTNPVAIGIP-SNRYYVSVDMATSASARGKLLEAA 188
Query 196 HKGVPVPPGCLIDVNGVPTTNPAVMQESPLGSLLTFAEHKGYALAAMCEILGGALSGGK- 254
KG +P +D G PTT+P + + GS+L F HKGYAL+ M EIL G L G
Sbjct 189 RKGESIPENVALDAEGKPTTDPEMALK---GSILPFGGHKGYALSFMIEILAGPLVGAAF 245
Query 255 ------TTHQETLQTSPDAILNCMTTIIINPELFGAPDCSAQTEAFAEWVKASPHDDDKP 308
T + E + T D ++ + +++P+ F AQ + F E VK+S
Sbjct 246 GTAVTGTANPEEMCTKGDLMMAIDPSKMVDPDEF-----RAQVDEFIEEVKSS-----GD 295
Query 309 ILLPGEWEVNTRRERQEQGIPLDAGSWQAICDAARQI 345
+L+PG+ E + R+ +GI LD + I AR++
Sbjct 296 VLIPGDIESMNIKRRRAEGIELDEKLLERILGIAREL 332
>P16142 Malate/(S)-sulfolactate dehydrogenase [Methanothermus
fervidus (strain ATCC 43054 / DSM 2088 / JCM 10308 / V24 S)]
Length=339
Score = 168 bits (426), Expect = 1e-52
Identities = 105/322 (33%), Positives = 167/322 (52%), Gaps = 16/322 (5%)
Query 14 SFIQAVFRQMGSEEQEAKLVADHLIAANLAGHDSHGIGMIPSYVRSWSQGHLQINHHAKI 73
S I + +G E+ AK+ AD ++ A+L G SHGIG P YV G ++ + + +I
Sbjct 10 SLIIKILNALGVSEEHAKITADVIVDADLKGFTSHGIGRFPQYVEGIKLGTIKTSGNIEI 69
Query 74 VKEAGAAVTLDGDRAFGQVAAHEAMALGIEKAHQHGIAAVALHNSHHIGRIGYWAEQCAA 133
KE + ++G+ GQV A++ M L IEKA G+ V +H+S+H G GY+++
Sbjct 70 EKETDSVALINGNHLLGQVVAYKGMKLAIEKAKNTGVGIVGIHDSNHFGIAGYYSDMAMK 129
Query 134 AGFVSIHFVSVVGIPMVAPFHGRDSRFGTNPFCVVFPRKDDFPLLLDYATSAIAFGKTRV 193
+ I + P VAP G+ GTNP + P +++ + +D +T+A+A GK
Sbjct 130 NDMIGITMTNTE--PAVAPLGGKIPVLGTNPIAISIP-SNEYYVAVDMSTAAVARGKLLE 186
Query 194 AWHKGVPVPPGCLIDVNGVPTTNPAVMQESPLGSLLTFAEHKGYALAAMCEILGGALSGG 253
A K +P G +D NG PTT+P E+ GS+L F HKGYAL M EIL G L
Sbjct 187 AARKNEKIPEGIAVDKNGNPTTDP---NEALNGSILPFGGHKGYALCFMIEILAGPLV-- 241
Query 254 KTTHQETLQTSPDAILNCM---TTIIINP-ELFGAPDCSAQTEAFAEWVKASPHDDDKPI 309
K ++ + D C I I+P + + + + F + +K++ K +
Sbjct 242 KAEFGSKVKGTVDPSQMCTKGDLLIAIDPSKFYDIEEFKRNVDEFVKEIKST----GKDV 297
Query 310 LLPGEWEVNTRRERQEQGIPLD 331
L+PG+ E ++R+++GI LD
Sbjct 298 LIPGDRERMNIKKREKEGIELD 319
>O59028 Malate dehydrogenase [Pyrococcus horikoshii (strain ATCC
700860 / DSM 12428 / JCM 9974 / NBRC 100139 / OT-3)]
Length=360
Score = 165 bits (418), Expect = 3e-51
Identities = 116/351 (33%), Positives = 173/351 (49%), Gaps = 15/351 (4%)
Query 6 RFDAQTLHSFIQAVFRQMGSEEQEAKLVADHLIAANLAGHDSHGIGMIPSYVRSWSQGHL 65
R L SFI V ++G E++AK+VAD+L+ A+L G +SHG+ + YV G +
Sbjct 13 RVPKDRLFSFIVRVLTKLGVPEEDAKIVADNLVMADLRGVESHGVQRLKRYVDGIISGGV 72
Query 66 QINHHAKIVKEAGAAVTLDGDRAFGQVAAHEAMALGIEKAHQHGIAAVALHNSHHIGRIG 125
++ ++++E + +DGD GQV + +M L I+KA GI V NS+H G G
Sbjct 73 NLHPKIRVIREGPSYALIDGDEGLGQVVGYRSMKLAIKKAKDTGIGIVIARNSNHYGIAG 132
Query 126 YWAEQCAAAGFVSIHFVSVVGIPMVAPFHGRDSRFGTNPFCVVFPRKDDFPLLLDYATSA 185
Y+A A G + I + P+VAP G + GTNP + P KD P LLD ATS
Sbjct 133 YYALMAAEEGMIGISMTN--SRPLVAPTGGIERILGTNPIALAAPTKDK-PFLLDMATSV 189
Query 186 IAFGKTRVAWHKGVPVPPGCLIDVNGVPTT-------NPAVMQESPLGSLLTFAEHKGYA 238
+ GK V KG +P G I+ G TT A++ G LL HKGY
Sbjct 190 VPIGKLEVYRRKGKDIPEGWAINREGNITTKVEEVFNGGALLPLGGFGELL--GGHKGYG 247
Query 239 LAAMCEILGGALSGGKTTHQETLQTSPDAILNCMTTIIINPELF-GAPDCSAQTEAFAEW 297
L+ M +IL G LSGG T + TS C ++I+ E F + + E
Sbjct 248 LSLMVDILSGILSGG-TWSKYVKNTSEKGSNVCHFFMVIDIEHFIPLEEFKEKISQMIEE 306
Query 298 VKAS-PHDDDKPILLPGEWEVNTRRERQEQGIPLDAGSWQAICDAARQIGM 347
+K+S H + + I + GE T R + GIP+ + + + A+++G+
Sbjct 307 IKSSRKHPEFERIWIHGEKGFLTMETRLKLGIPIYRKVLEELNEIAKRVGV 357
>Q5FB93 Delta(1)-pyrroline-2-carboxylate/Delta(1)-piperideine-2-carboxylate
reductase [Pseudomonas putida]
Length=341
Score = 147 bits (370), Expect = 2e-44
Identities = 104/331 (31%), Positives = 156/331 (47%), Gaps = 15/331 (5%)
Query 12 LHSFIQAVFRQMGSEEQEAKLVADHLIAANLAGHDSHGIGMIPSYVRSWSQGHLQINHHA 71
L S +QA+F++ G E A+++A + +A G SHG+ +P YV + + G +
Sbjct 17 LQSLLQAIFQRHGCSEAVARVLAHNCASAQRDGAHSHGVFRMPGYVSTLASGWVDGQATP 76
Query 72 KIVKEAGAAVTLDGDRAFGQVAAHEAMALGIEKAHQHGIAAVALHNSHHIGRIGYWAEQC 131
++ A V +D F Q A A L + KA GIA +A+HNSHH + E
Sbjct 77 QVSDVAAGYVRVDAAGGFAQPALAAARELLVAKARSAGIAVLAIHNSHHFAALWPDVEPF 136
Query 132 AAAGFVSIHFVSVVGIPMVAPFHGRDSRFGTNPFCVVFPRKDDFPLLLDYATSAIAFGKT 191
A G V++ V+ + V P R FGTNP P + P++ D ATSA+A G
Sbjct 137 AEEGLVALSVVN--SMTCVVPHGARKPLFGTNPIAFAAPCAEHDPIVFDMATSAMAHGDV 194
Query 192 RVAWHKGVPVPPGCLIDVNGVPTTNPAVMQESPLGSLLTFAEHKGYALAAMCEILGGALS 251
++A G +P G +D +G PTT+P + E G+LL F HKG AL+ M E+L AL+
Sbjct 195 QIAARAGQQLPEGMGVDADGQPTTDPKAILEG--GALLPFGGHKGSALSMMVELLAAALT 252
Query 252 GGKTTHQETLQTSPDAIL--NCMTTIIINPELFGAPDCSAQTEAFAEWVKASPHDDDKPI 309
GG + + P A I+INP A+ E FA+ +
Sbjct 253 GGHFSWEFDWSGHPGAKTPWTGQLIIVINPG-------KAEGERFAQRSRELVEHMQAVG 305
Query 310 L--LPGEWEVNTRRERQEQGIPLDAGSWQAI 338
L +PGE R +E+G+ + Q +
Sbjct 306 LTRMPGERRYREREVAEEEGVAVTEQELQGL 336
>P77555 Ureidoglycolate dehydrogenase (NAD(+)) [Escherichia coli
(strain K12)]
Length=349
Score = 140 bits (352), Expect = 9e-42
Identities = 100/329 (30%), Positives = 150/329 (46%), Gaps = 11/329 (3%)
Query 6 RFDAQTLHSFIQAVFRQMGSEEQEAKLVADHLIAANLAGHDSHGIGMIPSYVRSWSQGHL 65
+ +TLH I+ Q G + + A VA+ L+ A+ G SHG + Y S+G
Sbjct 2 KISRETLHQLIENKLCQAGLKREHAATVAEVLVYADARGIHSHGAVRVEYYAERISKGGT 61
Query 66 QINHHAKIVKEAGAAVTLDGDRAFGQVAAHEAMALGIEKAHQHGIAAVALHNSHHIGRIG 125
++ + + L D A GQVAA M I+ A Q+G+A V + H G I
Sbjct 62 NREPEFRLEETGPCSAILHADNAAGQVAAKMGMEHAIKTAQQNGVAVVGISRMGHSGAIS 121
Query 126 YWAEQCAAAGFVSIHFVSVVGIPMVAPFHGRDSRFGTNPFCVVFPRKDDFPLLLDYATSA 185
Y+ +Q A AGF+ I PMV PF G + +GTNP P + D L D AT+
Sbjct 122 YFVQQAARAGFIGISMCQ--SDPMVVPFGGAEIYYGTNPLAFAAPGEGDEILTFDMATTV 179
Query 186 IAFGKTRVAWHKGVPVPPGCLIDVNGVPTTNPAVMQESPLGSLLTFAEHKGYALAAMCEI 245
A+GK A + + +P +D NGVPTT+P + +LL A KGY L M ++
Sbjct 180 QAWGKVLDARSRNMSIPDTWAVDKNGVPTTDPFAVH-----ALLPAAGPKGYGLMMMIDV 234
Query 246 LGGALSGGKTTHQ-ETLQTSPDAILNC-MTTIIINPELFGAPDCSAQ--TEAFAEWVKAS 301
L G L G Q ++ A N I+INP F + + Q ++ E +
Sbjct 235 LSGVLLGLPFGRQVSSMYDDLHAGRNLGQLHIVINPNFFSSSELFRQHLSQTMRELNAIT 294
Query 302 PHDDDKPILLPGEWEVNTRRERQEQGIPL 330
P + PG+ + +R+ +GI +
Sbjct 295 PAPGFNQVYYPGQDQDIKQRKAAVEGIEI 323
>Q4U331 Delta(1)-pyrroline-2-carboxylate/Delta(1)-piperideine-2-carboxylate
reductase [Pseudomonas syringae pv. tomato]
Length=343
Score = 132 bits (331), Expect = 8e-39
Identities = 86/257 (33%), Positives = 130/257 (51%), Gaps = 6/257 (2%)
Query 12 LHSFIQAVFRQMGSEEQEAKLVADHLIAANLAGHDSHGIGMIPSYVRSWSQGHLQINHHA 71
L ++ +F G+ + A ++A++ +A G SHGI IP Y+ S + G +
Sbjct 18 LIDLLRRIFVVHGTSPEVADVLAENCASAQRDGSHSHGIFRIPGYLSSLASGWVD-GKAV 76
Query 72 KIVKEAGAA-VTLDGDRAFGQVAAHEAMALGIEKAHQHGIAAVALHNSHHIGRIGYWAEQ 130
+V++ GAA V +D F Q A A +L I+KA G+A +A+ SHH + E
Sbjct 77 PVVEDVGAAFVRVDACNGFAQPALAAARSLLIDKARSAGVAILAIRGSHHFAALWPDVEP 136
Query 131 CAAAGFVSIHFVSVVGIPMVAPFHGRDSRFGTNPFCVVFPRKDDFPLLLDYATSAIAFGK 190
A G V++ V+ + V P R FGTNP PR P++ D ATSAIA G
Sbjct 137 FAEQGLVALSMVN--SMTCVVPHGARQPLFGTNPIAFGAPRAGGEPIVFDLATSAIAHGD 194
Query 191 TRVAWHKGVPVPPGCLIDVNGVPTTNPAVMQESPLGSLLTFAEHKGYALAAMCEILGGAL 250
++A +G +P G +D +G+PT P + + G+LL F HKG AL+ M E+L L
Sbjct 195 VQIAAREGRLLPAGMGVDRDGLPTQEPRAILDG--GALLPFGGHKGSALSMMVELLAAGL 252
Query 251 SGGKTTHQETLQTSPDA 267
+GG + + P A
Sbjct 253 TGGNFSFEFDWSKHPGA 269
Score = 20.4 bits (41), Expect = 0.94
Identities = 13/49 (27%), Positives = 19/49 (39%), Gaps = 10/49 (20%)
Query 267 AILNCMTTII----------INPELFGAPDCSAQTEAFAEWVKASPHDD 305
+++N MT ++ NP FGAP + F A H D
Sbjct 146 SMVNSMTCVVPHGARQPLFGTNPIAFGAPRAGGEPIVFDLATSAIAHGD 194
>D7A0Y0 Delta(1)-pyrroline-2-carboxylate reductase [Starkeya novella
(strain ATCC 8093 / DSM 506 / JCM 20403 / CCM 1077 /
IAM 12100 / NBRC 12443 / NCIMB 10456)]
Length=341
Score = 125 bits (313), Expect = 3e-36
Identities = 97/337 (29%), Positives = 144/337 (43%), Gaps = 15/337 (4%)
Query 1 MESGHRFDAQTLHSFIQAVFRQMGSEEQEAKLVADHLIAANLAGHDSHGIGMIPSYVRSW 60
M+ R +H + G E+ A+ +A + A SHG+ + YV S
Sbjct 1 MDEPVRLSLAEVHVLCRDTLVAAGLGEEHAQAIARSITRAEADECHSHGLYRLIGYVASV 60
Query 61 SQGHLQINHHAKIVKEAGAAVTLDGDRAFGQVAAHEAMALGIEKAHQHGIAAVALHNSHH 120
G + + + + A + +D F +A + I A + GIAA+A+H+ +H
Sbjct 61 RSGKAERHALPALARATPAVLRVDAKHGFAPLAVETGVPALIAAAKEIGIAALAIHDCYH 120
Query 121 IGRIGYWAEQCAAAGFVSIHFVSVVGIPMVAPFHGRDSRFGTNPFCVVFPRKDDFPLLLD 180
+ E AG + F VG VAP G GTNPF +P P + D
Sbjct 121 FSALWADIEPAVEAGLAAWCFT--VGQCCVAPAGGTTPLLGTNPFAFGWPGPSGRPFIFD 178
Query 181 YATSAIAFGKTRVAWHKGVPVPPGCLIDVNGVPTTNPAVMQESPLGSLLTFAEHKGYALA 240
+ATSA A G+ + G +PPG + +G PTT+PA + G+LL F HKG AL+
Sbjct 179 FATSAAARGEIELKRRGGEKIPPGWAVGPDGAPTTDPAA---ALAGALLPFGGHKGSALS 235
Query 241 AMCEILGGALSGGKTTHQETLQTSPDA--ILNCMTTIIINPELFGAPDCS---AQTEAFA 295
M E++ G L G T+ Q + D L I I+P +FG + S A +
Sbjct 236 MMVELIAGPLIGDLTSRQSKAVENGDGGPPLGGELFIAIDPAVFGTGNLSSRLADADELF 295
Query 296 EWVKASPHDDDKPILLPGEWEVNTRRERQEQGIPLDA 332
KA P + LP E R + GI + A
Sbjct 296 ALAKAQP-----GVRLPSERRYQARERSRTNGIAVPA 327
>Q1QWN5 (2R)-3-sulfolactate dehydrogenase (NADP(+)) [Chromohalobacter
salexigens (strain ATCC BAA-138 / DSM 3043 / CIP 106854
/ NCIMB 13768 / 1H11)]
Length=333
Score = 119 bits (299), Expect = 2e-34
Identities = 89/310 (29%), Positives = 146/310 (47%), Gaps = 14/310 (5%)
Query 18 AVFRQMGSEEQEAKLVADHLIAANLAGHDSHGIGMIPSYVRSWSQGHLQINHHAKIVKEA 77
A +G EA++ A LI A G SHG+ +P Y+ G + + A+ V+ A
Sbjct 16 AALEAVGVPRWEAEVTARALIDAERDGLASHGLSRLPFYLAQARSGKVVADAQAR-VEVA 74
Query 78 GAAVTLDGDRAFGQVAAHEAMALGIEKAHQHGIAAVALHNSHHIGRIGYWAEQCAAAGFV 137
G+ + +D A + I A + G+ AVA+ SHH G G E+ A G V
Sbjct 75 GSVIRVDARHGLAFPAIARGVERAIPLARELGLVAVAIGGSHHFGVAGAPVERLAREGLV 134
Query 138 SIHFVSVVGIPMVAPFHGRDSRFGTNPFCVVFPRKDDFPLLLDYATSAIAFGKTRVAWHK 197
++ F + +AP+ G+ +GTNP PR+ PL++D + S +A GK +A
Sbjct 135 AMAFSNAPSA--MAPWGGKRPLYGTNPIAFATPRRGTDPLVIDLSLSKVARGKVMLAKKA 192
Query 198 GVPVPPGCLIDVNGVPTTNPAVMQESPLGSLLTFAEHKGYALAAMCEILGGALSGGKTTH 257
G P+P G +D+ G PTT+P + GS++ + KG +LA M E+L L+G
Sbjct 193 GEPIPEGWALDIEGRPTTDP---DAAIAGSMVPAGDAKGASLALMVELLTAGLTGSHFGF 249
Query 258 QETLQTSPDAILNCMTTIIINPELFGAPDCSAQTEAFAEWVKA--SPHDDDKPILLPGEW 315
Q + P+ + +++ A D + ++ + E ++A + + + LPG
Sbjct 250 QASSFFEPEGEAPSVGHLML------AFDPAHFSDGYLEHIEALFQAMLEQEGVRLPGTR 303
Query 316 EVNTRRERQE 325
RRER E
Sbjct 304 RHALRRERGE 313
>Q9I492 Delta(1)-pyrroline-2-carboxylate/Delta(1)-piperideine-2-carboxylate
reductase [Pseudomonas aeruginosa (strain ATCC
15692 / DSM 22644 / CIP 104116 / JCM 14847 / LMG 12228 / 1C
/ PRS 101 / PAO1)]
Length=334
Score = 118 bits (296), Expect = 7e-34
Identities = 78/238 (33%), Positives = 115/238 (48%), Gaps = 5/238 (2%)
Query 19 VFRQMGSEEQEAKLVADHLIAANLAGHDSHGIGMIPSYVRSWSQGHLQINHHAKIVKEAG 78
+ R+ E + VAD L+A SHGI + + + G + + ++ A
Sbjct 16 ILRRHAFSEAHVQAVADTLVAGERDECASHGIWRLLGCIATLKAGKVSADAEPELHDIAP 75
Query 79 AAVTLDGDRAFGQVAAHEAMALGIEKAHQHGIAAVALHNSHHIGRIGYWAEQCAAAGFVS 138
+ +D F Q A + +EKA GIAA+A++ H + E AG V+
Sbjct 76 GLLRVDAHGGFSQCAFRLGLPHLLEKARSQGIAAMAVNRCVHFSALWVEVEALTEAGLVA 135
Query 139 IHFVSVVGIPMVAPFHGRDSRFGTNPFCVVFPRKDDFPLLLDYATSAIAFGKTRVAWHKG 198
+ + VAP GR FGTNP +PR D P + D+ATSA+A G+ ++ G
Sbjct 136 L--ATTPSHAWVAPAGGRKPIFGTNPIAFGWPRPDGPPFVFDFATSAVARGEIQLHERAG 193
Query 199 VPVPPGCLIDVNGVPTTNPAVMQESPLGSLLTFAEHKGYALAAMCEILGGALSGGKTT 256
P+P G +D G PTT+ + G++LTF HKG ALAAM E+L G L G T+
Sbjct 194 KPIPLGWGVDEQGEPTTDASAALR---GAMLTFGGHKGSALAAMVELLAGPLIGDLTS 248
Lambda K H a alpha
0.322 0.135 0.425 0.792 4.96
Gapped
Lambda K H a alpha sigma
0.267 0.0410 0.140 1.90 42.6 43.6
Effective search space used: 1323000
Database: 9d5a5fed76d7f61c6ccdeda53f44ceaa.SwissProt.fasta
Posted date: May 31, 2024 8:37 AM
Number of letters in database: 4,858
Number of sequences in database: 14
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Neighboring words threshold: 11
Window for multiple hits: 40
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Data ...
