BLASTP 2.12.0+
Reference: Stephen F. Altschul, Thomas L. Madden, Alejandro A.
Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J.
Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of
protein database search programs", Nucleic Acids Res. 25:3389-3402.
Reference for composition-based statistics: Alejandro A. Schaffer,
L. Aravind, Thomas L. Madden, Sergei Shavirin, John L. Spouge, Yuri
I. Wolf, Eugene V. Koonin, and Stephen F. Altschul (2001),
"Improving the accuracy of PSI-BLAST protein database searches with
composition-based statistics and other refinements", Nucleic Acids
Res. 29:2994-3005.
Database: faeb6142f80c2fbd6ba851081b9b1616.SwissProt.fasta
19 sequences; 19,842 total letters
Query= ACIAD3624
Length=1043
Score E
Sequences producing significant alignments: (Bits) Value
P94177 Cation efflux system protein CzcA [Alcaligenes sp. (strain... 269 5e-78
P13511 Cobalt-zinc-cadmium resistance protein CzcA [Cupriavidus m... 267 2e-77
P25197 Nodulation protein NolG [Rhizobium meliloti (strain 1021)] 264 2e-76
B4EYA1 Multidrug resistance protein MdtC [Proteus mirabilis (stra... 257 4e-74
B7M458 Multidrug resistance protein MdtB [Escherichia coli O8 (st... 254 4e-73
B7LV39 Multidrug resistance protein MdtB [Escherichia fergusonii ... 254 5e-73
B7NCB1 Multidrug resistance protein MdtB [Escherichia coli O17:K5... 254 5e-73
B7NQB1 Multidrug resistance protein MdtB [Escherichia coli O7:K1 ... 254 5e-73
B7UTB3 Multidrug resistance protein MdtB [Escherichia coli O127:H... 253 1e-72
Q7N3E1 Multidrug resistance protein MdtC [Photorhabdus laumondii ... 252 2e-72
Q3Z0C9 Multidrug resistance protein MdtB [Shigella sonnei (strain... 252 2e-72
B7L9U8 Multidrug resistance protein MdtB [Escherichia coli (strai... 252 2e-72
P76398 Multidrug resistance protein MdtB [Escherichia coli (strai... 251 3e-72
P24177 Probable aminoglycoside efflux pump [Escherichia coli (str... 248 3e-71
Q8FWV9 Efflux pump membrane transporter BepG [Brucella suis biova... 247 1e-70
Q48815 Protein HelA [Legionella pneumophila] 246 2e-70
P24181 Multidrug export protein AcrF [Escherichia coli (strain K12)] 239 4e-68
P76399 Multidrug resistance protein MdtC [Escherichia coli (strai... 236 4e-67
P52002 Multidrug resistance protein MexB [Pseudomonas aeruginosa ... 234 2e-66
>P94177 Cation efflux system protein CzcA [Alcaligenes sp. (strain
CT14)]
Length=1063
Score = 269 bits (687), Expect = 5e-78
Identities = 261/1088 (24%), Positives = 484/1088 (44%), Gaps = 128/1088 (12%)
Query 8 WALKNKGLILYLMLLLAIVGIFSYSKLSQSEDPPFTFKVMVIKTYWPGATAKEVSTLVTD 67
+A++ + L+L + +A +GIFSY++L P T + + T PG + E VT
Sbjct 8 FAIQQRWLVLLAVFGMAGLGIFSYNRLPIDAVPDITNVQVQVNTSAPGYSPLETEQRVTY 67
Query 68 RIEKELMTTGQYDHIMAYSRPGESMVTFFAKDSLKSEQIPDVWYN---VRKKVNDIKQEL 124
IE + + + SR G S VT KD DV++ V +++ + K L
Sbjct 68 PIEVVMAGLPGLEQTRSLSRYGLSQVTVIFKDG------TDVYFARQLVNQRIQEAKDNL 121
Query 125 PVGV---QGPFFNDEFGDTFGNIYVLT-----------GEGFDYAVLKEYAD-RLQLELQ 169
P GV GP G IY+ T G + L+E D ++ +L+
Sbjct 122 PEGVVPAMGP-----ISTGLGEIYLWTVEAEEGARKADGTAYTPTDLREIQDWVVRPQLR 176
Query 170 RVPDVAKVELVGLQDQKIWIELSNTKMAQLGVPVTAIQQALQQQNNMVSAGFFETPSDRI 229
VP V ++ +G +++ + S ++A G+ +T + AL + N+ V AG+ E ++
Sbjct 177 NVPGVTEINTIGGFNKQYLVAPSLERLASYGLTLTDVVNALNKNNDNVGAGYIERRGEQY 236
Query 230 QVRLTGHLNRVEDLKHLPLLVG---DKTIQLGEVAEIYRGFSDPAQPRMRFMGQNGIGI- 285
VR G + +D+++ ++VG + I++ ++ ++ G + R +NG +
Sbjct 237 LVRAPGQVASEDDIRN--IIVGTAQGQPIRIRDIGDVEIG----KELRTGAATENGKEVV 290
Query 286 --AVSMRKGGDIIALGKHLETTFSDLQHTLPLGMKLEKVSDQPVAVQRSIHEFIKVLAEA 343
V M G + A+ K ++ + + T+P G+K+ V D+ V ++I K L E
Sbjct 291 LGTVFMLIGENSRAVSKAVDEKVASINRTMPEGVKIVTVYDRTRLVDKAIATVKKNLLEG 350
Query 344 VIIVLLVSFFSLG-FRTGLVVAFSIPLVLAMTFAGMHIFDVGLHKISLGALILALGLLVD 402
++V+++ F LG R L+ A IPL + TF GM + + + +SLGA L G+++D
Sbjct 351 AVLVIVILFLFLGNIRAALITATIIPLAMLFTFTGMVNYKISANLMSLGA--LDFGIIID 408
Query 403 DAIIAVEMMAIKMEQGY----------SRLKAAGFAWKSTAFPMLTGTLITAAGFLPIAT 452
A++ VE ++ R A K P++ G LI +LPI
Sbjct 409 GAVVIVENCVRRLAHAQEHHGRPLTRSERFHEVFAAAKEARRPLIFGQLIIMIVYLPIFA 468
Query 453 ANSSTGEYTRSIFQVVTIALIVSWVAAVLFVP-----YLGEKLLPDFNQMQQRVPWYQRI 507
G+ + V +AL+ + + +V FVP ++GE++ N++ +
Sbjct 469 LTGVEGKMFHPMAFTVVLALLGAMILSVTFVPAAVALFIGERVAEKENRLM--------L 520
Query 508 WAKLRKQPVPQLASYQEHHDPYQTRFYQTFRNMVEACVRYRKTVIVTTVLLFAGSLLLFK 567
WAK R +P ++E + V+ + + +
Sbjct 521 WAKRRYEP------------------------LLEKSLANTAVVLTFAAVSIVLCVAIAA 556
Query 568 FVPQQFFPPSNRAEILVDIKLEEGASLTATEQAVKKVEHFLSQQ-KGIDNYVAYVGTGS- 625
+ +F P N +I + G SL+ + + K +E L + I+ A GT
Sbjct 557 RLGSEFIPNLNEGDIAIQALRIPGTSLSQSVEMQKTIETTLKAKFPEIERVFARTGTAEI 616
Query 626 ------PRF---YLPL--DQQLPQASFAQFVVLASSLEDRNEI---RHSLDQQIKLLLPQ 671
P Y+ L ++ P+ +L++ E+ +I + Q I+L
Sbjct 617 ASDPMPPNISDGYIMLKPEKDWPEPKKTHAELLSAIQEEAGKIPGNNYEFSQPIQL---- 672
Query 672 ARTRVSLLENGPPVGYPLQYRVSGEDQNLVREWAQKVAKVIAENPNATNVHLDWGEPSKL 731
R + L +G V + ++ G+D N++ E A+KV+ V+ P A V ++ +
Sbjct 673 ---RFNELISG--VRSDVAVKIFGDDNNVLSETAKKVSAVLQGIPGAQEVKVEQTTGLPM 727
Query 732 IMLNIDQDRARQLGVSNTDLANFLNSSITGTVIDQYREKRELIEIRLRGDQAERVDVASL 791
+ + ID+++A + G++ +D+ + + + + G + + +I +R +A R +V +L
Sbjct 728 LTVKIDREKAARYGLNMSDVQDAVATGVGGRDSGTFFQGDRRFDIVVRLPEAVRGEVEAL 787
Query 792 ASLAIPTSHG-----GTVPLAQIARIEYRFEDGIIWHRDRLPTITVRADMRSQLQPATVV 846
L IP G +PL+++A +E I + I + A++R + + V
Sbjct 788 RRLPIPLPKGVDARTTFIPLSEVATLEMAPGPNQISRENGKRRIVISANVRGR-DIGSFV 846
Query 847 DQMKLQMQELRRQLPNGYLIDVGGTVEESAKGQESVNAGMPLFLAVVMTLLMVKLRSLSR 906
+ + +Q + ++P GY + GGT E+ + +P+ L +V LL ++
Sbjct 847 PEAEAAIQS-QVKIPAGYWMTWGGTFEQLQSATTRLQVVVPVALLLVFVLLFAMFNNIKD 905
Query 907 AFIVFLTAPLGLIGVTLFLLLFDKPFGFVAMLGTIALSGMIMRNALILIDQIEQDVAAGH 966
+VF P L G L L + P A +G IAL G+ + N L+++ I GH
Sbjct 906 GLLVFTGIPFALTGGILALWIRGIPMSITAAVGFIALCGVAVLNGLVMLSFIRSLREEGH 965
Query 967 EVWTAIIDATVRRFRPILLTALAAVLAMIPLSRSIFFG-----PMAVAIMGGLIVATFLT 1021
+ +A+ + R RP+L+TAL A L +P++ + G P+A ++GG++ +T LT
Sbjct 966 SLDSAVRVGALTRLRPVLMTALVASLGFVPMAIATGTGAEVQRPLATVVIGGILSSTALT 1025
Query 1022 LFFLPALY 1029
L LP LY
Sbjct 1026 LLVLPVLY 1033
Score = 40.4 bits (93), Expect = 1e-05
Identities = 70/359 (19%), Positives = 142/359 (40%), Gaps = 41/359 (11%)
Query 697 DQNLVREWAQKVAKVIAENPNATNVHLDWGEPSKLIMLNIDQDRARQLGVSNTDLANFLN 756
D +++W V + P T ++ G +K ++ +R G++ TD+ N LN
Sbjct 162 DLREIQDWV--VRPQLRNVPGVTEINTIGGF-NKQYLVAPSLERLASYGLTLTDVVNALN 218
Query 757 SSITGTVIDQYREKRELIEIRLRGDQAERVDVASLASLAIPTSHGGTVPLAQIARIEYRF 816
+ + E +R G A D+ ++ + T+ G + + I +E
Sbjct 219 KNNDNVGAGYIERRGEQYLVRAPGQVASEDDIRNII---VGTAQGQPIRIRDIGDVEIGK 275
Query 817 E--DGIIWHRDR---LPTITVRADMRSQLQPATVVDQMKLQMQELRRQLPNGY-LIDVGG 870
E G + L T+ + S+ V +++ + R +P G ++ V
Sbjct 276 ELRTGAATENGKEVVLGTVFMLIGENSRAVSKAVDEKVA----SINRTMPEGVKIVTVYD 331
Query 871 TVEESAKGQESVNAGMPLFLAVVMTLLMVKLRSLSRAFIVFLTAPLGLIGVTLFLLLFDK 930
K +V + +V+ +L + L ++ A I PL ++ T ++ K
Sbjct 332 RTRLVDKAIATVKKNLLEGAVLVIVILFLFLGNIRAALITATIIPLAML-FTFTGMVNYK 390
Query 931 PFGFVAMLGTIALSGMIMRNALILIDQIEQDVAAG--------------HEVWTAIIDAT 976
+ LG + G+I+ A+++++ + +A HEV+ A +A
Sbjct 391 ISANLMSLGALDF-GIIIDGAVVIVENCVRRLAHAQEHHGRPLTRSERFHEVFAAAKEAR 449
Query 977 VRRFRPILLTALAAVLAMIPLS-----RSIFFGPMAVAIMGGLIVATFLTLFFLPALYA 1030
RP++ L ++ +P+ F PMA ++ L+ A L++ F+PA A
Sbjct 450 ----RPLIFGQLIIMIVYLPIFALTGVEGKMFHPMAFTVVLALLGAMILSVTFVPAAVA 504
>P13511 Cobalt-zinc-cadmium resistance protein CzcA [Cupriavidus
metallidurans (strain ATCC 43123 / DSM 2839 / NBRC 102507
/ CH34)]
Length=1063
Score = 267 bits (683), Expect = 2e-77
Identities = 260/1088 (24%), Positives = 483/1088 (44%), Gaps = 128/1088 (12%)
Query 8 WALKNKGLILYLMLLLAIVGIFSYSKLSQSEDPPFTFKVMVIKTYWPGATAKEVSTLVTD 67
+A++ + L+L + +A +GIFSY++L P T + + T PG + E T
Sbjct 8 FAIQQRWLVLLAVFGMAGLGIFSYNRLPIDAVPDITNVQVQVNTSAPGYSPLETEQRATY 67
Query 68 RIEKELMTTGQYDHIMAYSRPGESMVTFFAKDSLKSEQIPDVWYN---VRKKVNDIKQEL 124
IE + + + SR G S VT KD DV++ V +++ + K L
Sbjct 68 PIEVVMAGLPGLEQTRSLSRYGLSQVTVIFKDGT------DVYFARQLVNQRIQEAKDNL 121
Query 125 PVGV---QGPFFNDEFGDTFGNIYVLT-----------GEGFDYAVLKEYADRL-QLELQ 169
P GV GP G IY+ T G + L+E D + + +L+
Sbjct 122 PEGVVPAMGPISTG-----LGEIYLWTVEAEEGARKADGTAYTPTDLREIQDWVVRPQLR 176
Query 170 RVPDVAKVELVGLQDQKIWIELSNTKMAQLGVPVTAIQQALQQQNNMVSAGFFETPSDRI 229
VP V ++ +G +++ + S ++A G+ +T + AL + N+ V AG+ E ++
Sbjct 177 NVPGVTEINTIGGFNKQYLVAPSLERLASYGLTLTDVVNALNKNNDNVGAGYIERRGEQY 236
Query 230 QVRLTGHLNRVEDLKHLPLLVGD---KTIQLGEVAEIYRGFSDPAQPRMRFMGQNGIGIA 286
VR G + +D++++ +VG + I++ ++ ++ G + R +NG +
Sbjct 237 LVRAPGQVASEDDIRNI--IVGTAQGQPIRIRDIGDVEIG----KELRTGAATENGKEVV 290
Query 287 ---VSMRKGGDIIALGKHLETTFSDLQHTLPLGMKLEKVSDQPVAVQRSIHEFIKVLAEA 343
V M G + A+ K ++ + + T+P G+K+ V D+ V ++I K L E
Sbjct 291 LGTVFMLIGENSRAVSKAVDEKVASINRTMPEGVKIVTVYDRTRLVDKAIATVKKNLLEG 350
Query 344 VIIVLLVSFFSLG-FRTGLVVAFSIPLVLAMTFAGMHIFDVGLHKISLGALILALGLLVD 402
++V+++ F LG R L+ A IPL + TF GM + + + +SLGA L G+++D
Sbjct 351 AVLVIVILFLFLGNIRAALITATIIPLAMLFTFTGMVNYKISANLMSLGA--LDFGIIID 408
Query 403 DAIIAVEMMAIKMEQGY----------SRLKAAGFAWKSTAFPMLTGTLITAAGFLPIAT 452
A++ VE ++ R A K P++ G LI +LPI
Sbjct 409 GAVVIVENCVRRLAHAQEHHGRPLTRSERFHEVFAAAKEARRPLIFGQLIIMIVYLPIFA 468
Query 453 ANSSTGEYTRSIFQVVTIALIVSWVAAVLFVP-----YLGEKLLPDFNQMQQRVPWYQRI 507
G+ + V +AL+ + + +V FVP ++GE++ N++ +
Sbjct 469 LTGVEGKMFHPMAFTVVLALLGAMILSVTFVPAAVALFIGERVAEKENRLM--------L 520
Query 508 WAKLRKQPVPQLASYQEHHDPYQTRFYQTFRNMVEACVRYRKTVIVTTVLLFAGSLLLFK 567
WAK R +P ++E + V+ + + +
Sbjct 521 WAKRRYEP------------------------LLEKSLANTAVVLTFAAVSIVLCVAIAA 556
Query 568 FVPQQFFPPSNRAEILVDIKLEEGASLTATEQAVKKVEHFLSQQ-KGIDNYVAYVGTGS- 625
+ +F P N +I + G SL+ + + K +E L + I+ A GT
Sbjct 557 RLGSEFIPNLNEGDIAIQALRIPGTSLSQSVEMQKTIETTLKAKFPEIERVFARTGTAEI 616
Query 626 ------PRF---YLPL--DQQLPQASFAQFVVLASSLEDRNEI---RHSLDQQIKLLLPQ 671
P Y+ L ++ P+ +L++ E+ +I + Q I+L
Sbjct 617 ASDLMPPNISDGYIMLKPEKDWPEPKKTHAELLSAIQEEAGKIPGNNYEFSQPIQL---- 672
Query 672 ARTRVSLLENGPPVGYPLQYRVSGEDQNLVREWAQKVAKVIAENPNATNVHLDWGEPSKL 731
R + L +G V + ++ G+D N++ E A+KV+ V+ P A V ++ +
Sbjct 673 ---RFNELISG--VRSDVAVKIFGDDNNVLSETAKKVSAVLQGIPGAQEVKVEQTTGLPM 727
Query 732 IMLNIDQDRARQLGVSNTDLANFLNSSITGTVIDQYREKRELIEIRLRGDQAERVDVASL 791
+ + ID+++A + G++ +D+ + + + + G + + +I +R +A R +V +L
Sbjct 728 LTVKIDREKAARYGLNMSDVQDAVATGVGGRDSGTFFQGDRRFDIVVRLPEAVRGEVEAL 787
Query 792 ASLAIPTSHG-----GTVPLAQIARIEYRFEDGIIWHRDRLPTITVRADMRSQLQPATVV 846
L IP G +PL+++A +E I + I + A++R + + V
Sbjct 788 RRLPIPLPKGVDARTTFIPLSEVATLEMAPGPNQISRENGKRRIVISANVRGR-DIGSFV 846
Query 847 DQMKLQMQELRRQLPNGYLIDVGGTVEESAKGQESVNAGMPLFLAVVMTLLMVKLRSLSR 906
+ + +Q + ++P GY + GGT E+ + +P+ L +V LL ++
Sbjct 847 PEAEAAIQS-QVKIPAGYWMTWGGTFEQLQSATTRLQVVVPVALLLVFVLLFAMFNNIKD 905
Query 907 AFIVFLTAPLGLIGVTLFLLLFDKPFGFVAMLGTIALSGMIMRNALILIDQIEQDVAAGH 966
+VF P L G L L + P A +G IAL G+ + N L+++ I GH
Sbjct 906 GLLVFTGIPFALTGGILALWIRGIPMSITAAVGFIALCGVAVLNGLVMLSFIRSLREEGH 965
Query 967 EVWTAIIDATVRRFRPILLTALAAVLAMIPLSRSIFFG-----PMAVAIMGGLIVATFLT 1021
+ +A+ + R RP+L+TAL A L +P++ + G P+A ++GG++ +T LT
Sbjct 966 SLDSAVRVGALTRLRPVLMTALVASLGFVPMAIATGTGAEVQRPLATVVIGGILSSTALT 1025
Query 1022 LFFLPALY 1029
L LP LY
Sbjct 1026 LLVLPVLY 1033
Score = 40.4 bits (93), Expect = 1e-05
Identities = 70/359 (19%), Positives = 142/359 (40%), Gaps = 41/359 (11%)
Query 697 DQNLVREWAQKVAKVIAENPNATNVHLDWGEPSKLIMLNIDQDRARQLGVSNTDLANFLN 756
D +++W V + P T ++ G +K ++ +R G++ TD+ N LN
Sbjct 162 DLREIQDWV--VRPQLRNVPGVTEINTIGGF-NKQYLVAPSLERLASYGLTLTDVVNALN 218
Query 757 SSITGTVIDQYREKRELIEIRLRGDQAERVDVASLASLAIPTSHGGTVPLAQIARIEYRF 816
+ + E +R G A D+ ++ + T+ G + + I +E
Sbjct 219 KNNDNVGAGYIERRGEQYLVRAPGQVASEDDIRNII---VGTAQGQPIRIRDIGDVEIGK 275
Query 817 E--DGIIWHRDR---LPTITVRADMRSQLQPATVVDQMKLQMQELRRQLPNGY-LIDVGG 870
E G + L T+ + S+ V +++ + R +P G ++ V
Sbjct 276 ELRTGAATENGKEVVLGTVFMLIGENSRAVSKAVDEKVA----SINRTMPEGVKIVTVYD 331
Query 871 TVEESAKGQESVNAGMPLFLAVVMTLLMVKLRSLSRAFIVFLTAPLGLIGVTLFLLLFDK 930
K +V + +V+ +L + L ++ A I PL ++ T ++ K
Sbjct 332 RTRLVDKAIATVKKNLLEGAVLVIVILFLFLGNIRAALITATIIPLAML-FTFTGMVNYK 390
Query 931 PFGFVAMLGTIALSGMIMRNALILIDQIEQDVAAG--------------HEVWTAIIDAT 976
+ LG + G+I+ A+++++ + +A HEV+ A +A
Sbjct 391 ISANLMSLGALDF-GIIIDGAVVIVENCVRRLAHAQEHHGRPLTRSERFHEVFAAAKEAR 449
Query 977 VRRFRPILLTALAAVLAMIPLS-----RSIFFGPMAVAIMGGLIVATFLTLFFLPALYA 1030
RP++ L ++ +P+ F PMA ++ L+ A L++ F+PA A
Sbjct 450 ----RPLIFGQLIIMIVYLPIFALTGVEGKMFHPMAFTVVLALLGAMILSVTFVPAAVA 504
>P25197 Nodulation protein NolG [Rhizobium meliloti (strain 1021)]
Length=1065
Score = 264 bits (675), Expect = 2e-76
Identities = 239/1036 (23%), Positives = 459/1036 (44%), Gaps = 64/1036 (6%)
Query 19 LMLLLAIVGIFSYSKLSQSEDPPFTFKVMVIKTYWPGATAKEVSTLVTDRIEKELMTTGQ 78
+M+++ ++G+FSY +L P V+V+ T + GA+ + V + ++ IE L T G
Sbjct 17 MMVMILVLGLFSYGRLGVDHYPETDLPVVVVATTYTGASPESVESEISRPIEAALNTIGG 76
Query 79 YDHIMAYSRPGESMVTFFAKDSLKSEQIPDVWYNVRKKVNDIKQELPVGVQGPFFN--DE 136
D I + S G S+V + + S+ D VR +V ++ + P GV P
Sbjct 77 IDTITSESYEGRSIVVVQFEVDVDSQ---DAAQEVRDRVARLETKFPDGVATPQVTRYKP 133
Query 137 FGDTFGNIYVLTGEGFDYAVLKEYADRLQLELQRVPDVAKVELVGLQDQKIWIELSNTKM 196
G ++ V + + + L + V +V L+G ++++ + + ++
Sbjct 134 EGQAILSVAVSSTSRTLPEITTLATRVINNRLSVISGVGQVSLIGSSERQVLVVVDPDRL 193
Query 197 AQLGVPVTAIQQALQQQNNMVSAGFFETPSDRIQVRLTGHLNRVEDLKHLPLLVGDKT-- 254
G+ V+ + +A++ +N +AG + ++ V + G + + +V +
Sbjct 194 GAYGLAVSTVIEAIRGENQDRAAGTLISGINQRIVTVEGRIANTSGFNRI--IVAQRNGY 251
Query 255 -IQLGEVAEIYRGFSDPAQPRMRFMGQNGIGIAVSMRKGGDIIALGKHLETTFSDLQHTL 313
+ L EVA I ++ + GQ +G+ + +G + + + + S L L
Sbjct 252 PVYLSEVATILDTGAEVTS-LANYQGQTTLGLHIVKVQGANTVEVASAVRREVSALNAEL 310
Query 314 P---LGMKLEKVSDQPVAVQRSIHEFIKVLAEA-VIIVLLVSFFSLGFRTGLVVAFSIPL 369
+ + + + + +P+A Q + + + L E V+ VL+V F +R+ ++ ++P+
Sbjct 311 TKDNVQLTITRDNSRPIASQ--VSQVQRTLVEGGVLSVLIVFIFLNSWRSTVITGLTLPI 368
Query 370 VLAMTFAGMHIFDVGLHKISLGALILALGLLVDDAIIAVEMMAIKMEQGYSRLKAAGFAW 429
+ TFA ++ L+ ++L AL L++G+L+DDAI+ E + ++ G ++AA
Sbjct 369 SVIGTFAAIYALGFTLNIMTLMALSLSIGILIDDAIVVRENITRHLQMGKDPVRAALDGT 428
Query 430 KSTAFPMLTGTLITAAGFLPIATANSSTGEYTRSIFQVVTIALIVSWVAAVLFVPYLGEK 489
+L+ TL A FLP+A G + V +A+++S LFV + +
Sbjct 429 NEIGLAVLSTTLCIVAVFLPVAFMGGLIGRFFLQFGVTVAVAVVIS-----LFVSFTLDP 483
Query 490 LLPDFNQMQQRVPWYQRIWAKLRKQPVPQLASYQ---EHHDPYQTRFYQTFRNMVEACVR 546
+L +W + Q + + E D + +R+++
Sbjct 484 MLSS-------------VWCDPQSQKTAKRGFFGQLIERFDQWFEGLASRYRSVIYFTFD 530
Query 547 YRKTVIVTTVLLFAGSLLLFKFVPQQFFPPSNRAEILVDIKLEEGASLTATEQAVKKVEH 606
YRKT I + +F SLLL + +F PP ++ E+ + ++ EGASL V ++E
Sbjct 531 YRKTTIAIVLGMFVVSLLLVPRIGTEFLPPPDQGEVSISLEANEGASLDYMAAKVGQIER 590
Query 607 FLSQQKGIDNYVAYVGTGSPRFYLPLDQQLPQASFAQFVVLASSLEDRNEIRHSLDQQIK 666
L + + + + + +G R + +A A V L S + R + +L +
Sbjct 591 ALREFNYVSSTYSTINSGEMRGF-------NKALVA--VQLVHSSQRRLKTAETLGPIRR 641
Query 667 LLLPQARTRVSLLENGPPVGY--PLQYRVSGEDQNLVREWAQKVAKVIAENPNATNVHLD 724
L A +S+ + VG PLQ + G+ +R + + V+A P AT +
Sbjct 642 RLSRIAGLEISVGQRSEVVGSIKPLQLSILGDGDEELRRISDHITSVLAAIPGATEIESS 701
Query 725 WGEPSKLIMLNIDQDRARQLGVSNTDLANFLNSSITGTVIDQYREKR-ELIEIRLRGDQA 783
+ + + + ++ A LGVS + + L S + G I + E ++ +R A
Sbjct 702 IEKLRPTLAVRVRREAASDLGVSIATIGDTLRSLVAGDAISVWNSPDGETHDVVVRLPAA 761
Query 784 ERVDVASLASLAIPTSHGGT------VPLAQIARIEYRFEDGIIWHRDRLPTITVRADMR 837
R + A L +L I T+ V L Q+A + I +D I + +++
Sbjct 762 GRENAAQLRNLPIATARMDDNGKPIMVLLDQVADVVESTAPAQITRKDLSRDIRISSNIE 821
Query 838 SQLQPATVVDQMKLQMQELRRQLPNGYLIDVGGTVEESAKGQESVNAGMPLFLAVVMTLL 897
+ V D L+ + +P G+ I GG E + + + + + +L
Sbjct 822 GRTLGDVVAD---LKAAMTKMDIPVGFRISFGGDAENLTESTAYALQSLAMAVIFIYIIL 878
Query 898 MVKLRSLSRAFIVFLTAPLGLIGVTLFLLLFDKPFGFVAMLGTIALSGMIMRNALILIDQ 957
+ S + + +T PL L+GV L LL +M+G + L G++ +NA++L+D
Sbjct 879 ASQFGSFIQPIAIIMTMPLSLMGVLLGLLFTGSTLNMFSMIGIMMLMGLVTKNAILLVDY 938
Query 958 IEQDVAAGHEVWTAIIDATVRRFRPILLTALAAVLAMIPLSRSIFFG-----PMAVAIMG 1012
V G + ++ DA R RPI++T LA + M+P + + G PMA AI+G
Sbjct 939 SNLGVREGKSLRQSLADAGAVRLRPIVMTTLAMIFGMLPTALGLGEGGAQRAPMAHAIIG 998
Query 1013 GLIVATFLTLFFLPAL 1028
GLI +T L+L F+P +
Sbjct 999 GLISSTLLSLVFVPVV 1014
>B4EYA1 Multidrug resistance protein MdtC [Proteus mirabilis (strain
HI4320)]
Length=1027
Score = 257 bits (656), Expect = 4e-74
Identities = 232/1031 (23%), Positives = 455/1031 (44%), Gaps = 62/1031 (6%)
Query 19 LMLLLAIVGIFSYSKLSQSEDPPFTFKVMVIKTYWPGATAKEVSTLVTDRIEKELMTTGQ 78
L L +++ G + L + P + V+ I PGA+ + +++ V +E+ L
Sbjct 17 LSLAISLCGALGFMLLPVAPLPQVDYPVINIYASLPGASPETMASSVATPLERSLGRIAG 76
Query 79 YDHIMAYSRPGESMVTFFAKDSLKSEQIPDVWYNVRKKVNDIKQELPVGVQGP--FFNDE 136
D + + S G + +T ++ I +V+ +N + LP G+ ++
Sbjct 77 IDEMTSSSALGSTSITLVFD---LNKDINTAARDVQAALNASQSLLPSGMPSRPRYYKSN 133
Query 137 FGDTFGNIYVLTGEGFDYAVLKEYAD-RLQLELQRVPDVAKVELVGLQDQKIWIELSNTK 195
D I LT E + L + A RL ++ ++ V++V + G + + L+
Sbjct 134 PSDAPIMILTLTSETQNTGELYDLASTRLAQKISQIEGVSEVSVGGGSLPAVRVALNPDA 193
Query 196 MAQLGVPVTAIQQALQQQNNMVSAGFFETPSDRIQVRLTGHLNRVEDLKHLPLLVG---D 252
+ V + +++A+ Q N GF +R Q++ L++ +D + P++V D
Sbjct 194 LFNQNVSLDDVRKAISQSNVRRPQGFIHNDENRWQIQTNDELSKAQDYR--PIIVHYNQD 251
Query 253 KTIQLGEVAEIYRGFSDPAQPRMRFMGQNGIGIAVSMRKGGDIIALGKHLETTFSDLQHT 312
++L +VA++ + M G+ I + + G +II + +L+
Sbjct 252 AIVRLSDVAQVTDSVQNARAAGMSG-GEPAILLVIRREAGANIIETVNRIRDELPELREL 310
Query 313 LPLGMKLEKVSDQPVAVQRSIHEFIKVLAEAVIIVLLVSFFSL-GFRTGLVVAFSIPLVL 371
LP + L+ D+ ++ S+ E + LA AV +V+LV F L R L+ A ++P+ L
Sbjct 311 LPASVNLKVAQDRTPTIRASLAEVERALAIAVALVILVVFLFLRSGRATLIPAVAVPVSL 370
Query 372 AMTFAGMHIFDVGLHKISLGALILALGLLVDDAIIAVEMMAIKMEQGYSRLKAAGFAWKS 431
TF+ M++ L+ +SL AL +A G +VDDAI+ +E ++ +E G +AA
Sbjct 371 IGTFSAMYLCGFSLNNLSLMALTVATGFVVDDAIVVLENISRHIENGLKPKQAALKGVSE 430
Query 432 TAFPMLTGTLITAAGFLPIATANSSTGEYTRSIFQVVTIALIVSWVAAVLFVPYLGEKLL 491
F +L+ ++ A F+P+ + G + +T A+ +S ++ P +
Sbjct 431 VGFTVLSMSISLVAVFIPLLLMDGLVGRLFKEFAITLTTAIGISLFVSLTLTPMM----- 485
Query 492 PDFNQMQQRVPWYQRIWAKLRKQPVPQLASYQEHHDPYQTRFYQTFRNMVEACVRYRKTV 551
A L K P+ S+ R Q + ++A +R+++ +
Sbjct 486 ----------------CAHLLKGIKPKAQSHLRGFGKLIFRLQQGYSVTLQAALRHKRWI 529
Query 552 IVTTVLLFAGSLLLFKFVPQQFFPPSNRAEILVDIKLEEGASLTATEQAVKKVEHFLSQQ 611
+ + + L+ P+ FFP + ++ ++ ++ S + ++ + + ++
Sbjct 530 MAIFITTLGLNAYLYISAPKTFFPDQDTGRLMGFVRADQSISFQSMKEKMTRFMQEINAD 589
Query 612 KGIDNYVAYVGTG---SPRFYLPLDQQLPQASFAQFVVLASSLEDRNEIRHSLDQQIKLL 668
K +D+ + G G S ++ L+ + A V+ ++ NE +L L
Sbjct 590 KDVDSVTGFTGGGRINSGFMFISLNPLSERTDSANQVINRLRIKLANEPGATL-----FL 644
Query 669 LPQARTRVSLLENGPPVGYPLQYRVSGEDQNLVREWAQKVAKVIAENPNATNVHLDWGEP 728
+P R G Q+ + +D + +R+W + K + E P +V+ D +
Sbjct 645 MPVQDVRA----GGRQANASYQFTLLADDLSELRKWEPLIRKALGELPELVDVNSDKEDK 700
Query 729 SKLIMLNIDQDRARQLGVSNTDLANFLNSSITGTVIDQYREKRELIEIRLRGDQAERVDV 788
+ L D+D QLG++ +D N LN++ I ++ + + DV
Sbjct 701 GAEMALTYDRDTMSQLGINVSDANNLLNNAFGQRQISTIYAPLNQYKVVMEVSEQYTQDV 760
Query 789 ASLASLAIPTSHGGTVPLAQIARIEYRFEDGIIWHRDRLPTITVRADMRSQLQPATVVDQ 848
++L + + + G +PL+ A + H+ T+ ++ + ++
Sbjct 761 SALDKMYVMNTQGERIPLSAFASWYPANAPLSVNHQGLSAASTIAFNVPEGYTLSDAINA 820
Query 849 MKLQMQELRRQLPNGYLIDVGGTVEESAK-GQESVNAGMPLFLAVVMT---LLMVKLRSL 904
++ M EL +PN V GT +A+ QE++ + + L LA ++T +L V S
Sbjct 821 IERTMTEL--GVPN----TVRGTFAGTAQIFQETIKSQLILILAAIVTVYIVLGVLYESY 874
Query 905 SRAFIVFLTAPLGLIGVTLFLLLFDKPFGFVAMLGTIALSGMIMRNALILID-QIEQDVA 963
+ T P +G L L LFD PF +A++G + L G++ +NA+I++D I
Sbjct 875 IHPLTILSTLPSAGVGALLALRLFDTPFSLIALIGIMLLIGIVKKNAIIMVDFAITAQRE 934
Query 964 AGHEVWTAIIDATVRRFRPILLTALAAVLAMIPLSRSIFFG-----PMAVAIMGGLIVAT 1018
AII A++ RFRPI++T LAA+ +PL S G P+ + I+GGL+++
Sbjct 935 GKLSAQEAIIQASLLRFRPIIMTTLAALFGALPLMLSSGDGAELRQPLGITIVGGLLMSQ 994
Query 1019 FLTLFFLPALY 1029
LTL+ P +Y
Sbjct 995 LLTLYTTPIIY 1005
>B7M458 Multidrug resistance protein MdtB [Escherichia coli O8
(strain IAI1)]
Length=1040
Score = 254 bits (649), Expect = 4e-73
Identities = 231/1049 (22%), Positives = 458/1049 (44%), Gaps = 93/1049 (9%)
Query 19 LMLLLAIVGIFSYSKLSQSEDPPFTFKVMVIKTYWPGATAKEVSTLVTDRIEKELMTTGQ 78
LM+ + + GI Y L S P + + + T +PGA+ +++ VT +E++
Sbjct 26 LMVAILLAGIIGYRALPVSALPEVDYPTIQVVTLYPGASPDVMTSAVTAPLERQFGQMSG 85
Query 79 YDHIMAYSRPGESMVTFFAKDSLKSEQIPDVWYNVRKKVNDIKQELPVGVQGPFFNDEFG 138
+ + S G S++T + +L + V+ +N LP + P +
Sbjct 86 LKQMSSQSSGGASVITLQFQLTLPLDVAEQ---EVQAAINAATNLLPSDLPNPPVYSKVN 142
Query 139 DTFGNIYVL--TGEGFDYAVLKEYAD-RLQLELQRVPDVAKVELVGLQDQKIWIELSNTK 195
I L T +++ + R+ ++ ++ V V L G Q + ++L+
Sbjct 143 PADPPIMTLAVTSTAMPMTQVEDMVETRVAQKISQISGVGLVTLSGGQRPAVRVKLNAQA 202
Query 196 MAQLGVPVTAIQQALQQQNNMVSAGFFETPSDRIQVRLTGHLNRVEDLKHLPLLVGDKT- 254
+A LG+ ++ A+ N + G + PS + + + E+ + L + +
Sbjct 203 IAALGLTSETVRTAITGANVNSAKGSLDGPSRAVTLSANDQMQSAEEYRQLIIAYQNGAP 262
Query 255 IQLGEVAEIYRGFSDPAQPRMRFMG-----QNGIGIAVSMRKGGDIIALGKHLETTFSDL 309
I+LG+VA + +G + ++G + I + V + G +II+ + L
Sbjct 263 IRLGDVATVEQGAENS------WLGAWANKEQAIVMNVQRQPGANIISTADSIRQMLPQL 316
Query 310 QHTLPLGMKLEKVSDQPVAVQRSIHEF-IKVLAEAVIIVLLVSFFSLGFRTGLVVAFSIP 368
+LP +K+ +SD+ ++ S+++ +++ ++V+++ F ++ F++P
Sbjct 317 TESLPKSVKVTVLSDRTTNIRASVNDTQFELMMAIALVVMIIYLFLRNIPATIIPGFAVP 376
Query 369 LVLAMTFAGMHIFDVGLHKISLGALILALGLLVDDAIIAVEMMAIKMEQGYSRLKAAGFA 428
L L TFA M D ++ ++L AL +A G +VDDAI+ +E ++ +E+G L AA
Sbjct 377 LSLIGTFAVMVFLDFSINNLTLMALTIATGFVVDDAIVVIENISRYIEKGEKPLAAALKG 436
Query 429 WKSTAFPMLTGTLITAAGFLPIATANSSTGEYTRSIFQVVTIALIVSWVAAVLFVPYLGE 488
F +++ T A +P+ G R + +A+++S V ++ P +
Sbjct 437 AGEIGFTIISLTFSLIAVLIPLLFMGDIVGRLFREFAITLAVAILISAVVSLTLTPMMCA 496
Query 489 KLLPDFNQMQQRVPWYQRIWAKLRKQPVPQ----LASYQEHHDPYQTRFYQTFRNMVEAC 544
++L + +Q + R K+ + + LA H P+ T
Sbjct 497 RMLSQESLRKQNR--FSRASEKMFDRIIAAYGRGLAKVLNH--PWLTL------------ 540
Query 545 VRYRKTVIVTTVLLFAGSLLLFKFVPQQFFPPSNRAEILVDIKLEEGASLTATEQAVKKV 604
+V ++T+LL S+LL+ F+P+ FFP + I ++ + +S Q ++V
Sbjct 541 -----SVALSTLLL---SVLLWVFIPKGFFPVQDNGIIQGTLQAPQSSSFANMAQRQRQV 592
Query 605 EHFLSQQKGIDNYVAYVGTGSPRFYLPLDQQLPQASFAQFVVLASSLEDRNEIRHSLDQQ 664
+ Q + + ++VG +D P + A+ + L++R D +
Sbjct 593 ADVILQDPAVQSLTSFVG---------VDGTNPSLNSARLQINLKPLDER-------DDR 636
Query 665 IKLLLPQARTRVSLLENGPPVGYPLQ--------------YRVSGEDQNLVREWAQKVAK 710
++ ++ + +T V + P Q + + + + W ++ +
Sbjct 637 VQKVIARLQTAVDKVPGVDLFLQPTQDLTIDTQVSRTQYQFTLQATSLDALSTWVPELME 696
Query 711 VIAENPNATNVHLDWGEPSKLIMLNIDQDRARQLGVSNTDLANFLNSSITGTVIDQYREK 770
+ + P ++V DW + + +N+D+D A +LG+S D+ N L ++ +I +
Sbjct 697 KLQQLPQLSDVSSDWQDKGLVAYVNVDRDSASRLGISMADVDNALYNAFGQRLISTIYTQ 756
Query 771 RELIEIRLRGDQAERVDVASLASLAIPTSHGGTVPLAQIARIEYRFEDGIIWHRDRLPTI 830
+ L + +A+L ++ + +S GG VPL+ IA+IE RF I H D+ P
Sbjct 757 ANQYRVVLEHNTENTPGLAALDTIRLTSSDGGVVPLSSIAKIEQRFAPLSINHLDQFPVT 816
Query 831 TVRADMRSQLQPATVVDQMKLQMQELRRQLPNGYLIDVGGTVEESAKGQESVNAGMPLFL 890
T+ ++ V + E LP +D+ + S +S +
Sbjct 817 TISFNVPDNYSLGDAV--QAIMDTEKTLNLP----VDITTQFQGSTLAFQSALGSTVWLI 870
Query 891 AVVMTLLMVKLRSLSRAFI----VFLTAPLGLIGVTLFLLLFDKPFGFVAMLGTIALSGM 946
+ + + L L +FI + T P +G L L++ +A++G I L G+
Sbjct 871 VAAVVAMYIVLGILYESFIHPITILSTLPTAGVGALLALMIAGSELDVIAIIGIILLIGI 930
Query 947 IMRNALILID-QIEQDVAAGHEVWTAIIDATVRRFRPILLTALAAVLAMIPLSRSIFFG- 1004
+ +NA+++ID + + G AI A + RFRPIL+T LAA+L +PL S G
Sbjct 931 VKKNAIMMIDFALAAEREQGMSPRDAIYQACLLRFRPILMTTLAALLGALPLMLSTGVGA 990
Query 1005 ----PMAVAIMGGLIVATFLTLFFLPALY 1029
P+ + ++GGLIV+ LTLF P +Y
Sbjct 991 ELRRPLGIGMVGGLIVSQVLTLFTTPVIY 1019
Score = 48.1 bits (113), Expect = 5e-08
Identities = 47/254 (19%), Positives = 105/254 (41%), Gaps = 27/254 (11%)
Query 794 LAIPTSHGGTVPLAQIARIEYRFEDGII--WHRDRLPTITVRADMRSQLQPA----TVVD 847
L I +G + L +A +E E+ + W + M Q QP + D
Sbjct 253 LIIAYQNGAPIRLGDVATVEQGAENSWLGAWANKEQAIV-----MNVQRQPGANIISTAD 307
Query 848 QMKLQMQELRRQLPNGYLIDVGGTVEESAKGQESVNAG---MPLFLAVVMTLLMVKLRSL 904
++ + +L LP + V + + + SVN + + +A+V+ ++ + LR++
Sbjct 308 SIRQMLPQLTESLPKSVKVTV--LSDRTTNIRASVNDTQFELMMAIALVVMIIYLFLRNI 365
Query 905 SRAFIVFLTAPLGLIGVTLFLLLFDKPFGFVAMLGTIALSGMIMRNALILIDQIEQDVAA 964
I PL LIG ++ D + ++ +G ++ +A+++I+ I + +
Sbjct 366 PATIIPGFAVPLSLIGTFAVMVFLDFSINNLTLMALTIATGFVVDDAIVVIENISRYIEK 425
Query 965 GHEVWTAIIDATVRRFRPILLTALAAVLAMIPLSRSIFFGPM--------AVAIMGGLIV 1016
G + A + I+ + + +IPL +F G + A+ + +++
Sbjct 426 GEKPLAAALKGAGEIGFTIISLTFSLIAVLIPL---LFMGDIVGRLFREFAITLAVAILI 482
Query 1017 ATFLTLFFLPALYA 1030
+ ++L P + A
Sbjct 483 SAVVSLTLTPMMCA 496
>B7LV39 Multidrug resistance protein MdtB [Escherichia fergusonii
(strain ATCC 35469 / DSM 13698 / CCUG 18766 / IAM 14443
/ JCM 21226 / LMG 7866 / NBRC 102419 / NCTC 12128 / CDC 0568-73)]
Length=1040
Score = 254 bits (648), Expect = 5e-73
Identities = 231/1049 (22%), Positives = 457/1049 (44%), Gaps = 93/1049 (9%)
Query 19 LMLLLAIVGIFSYSKLSQSEDPPFTFKVMVIKTYWPGATAKEVSTLVTDRIEKELMTTGQ 78
LM+ + + GI Y L S P + + + T +PGA+ +++ VT +E++
Sbjct 26 LMVAILLAGIIGYRALPVSALPEVDYPTIQVVTLYPGASPDVMTSAVTAPLERQFGQMSG 85
Query 79 YDHIMAYSRPGESMVTFFAKDSLKSEQIPDVWYNVRKKVNDIKQELPVGVQGPFFNDEFG 138
+ + S G S++T + +L + V+ +N LP + P +
Sbjct 86 LKQMSSQSSGGASVITLQFQLTLPLDVAEQ---EVQAAINAATNLLPSDLPNPPVYSKVN 142
Query 139 DTFGNIYVL--TGEGFDYAVLKEYAD-RLQLELQRVPDVAKVELVGLQDQKIWIELSNTK 195
I L T +++ + R+ ++ ++ V V L G Q + ++L+
Sbjct 143 PADPPIMTLAVTSTAMPMTQVEDMVETRVAQKISQISGVGLVTLSGGQRPAVRVKLNAQA 202
Query 196 MAQLGVPVTAIQQALQQQNNMVSAGFFETPSDRIQVRLTGHLNRVEDLKHLPLLVGDKT- 254
+A LG+ ++ A+ N + G + PS + + + E+ + L + +
Sbjct 203 IAALGLTSETVRTAITGANVNSAKGSLDGPSRAVTLSANDQMQSAEEYRQLIIAYQNGAP 262
Query 255 IQLGEVAEIYRGFSDPAQPRMRFMG-----QNGIGIAVSMRKGGDIIALGKHLETTFSDL 309
I+LG+VA + +G + ++G + I + V + G +II+ + L
Sbjct 263 IRLGDVATVEQGAENS------WLGAWANKEQAIVMNVQRQPGANIISTADSIRQMLPQL 316
Query 310 QHTLPLGMKLEKVSDQPVAVQRSIHEF-IKVLAEAVIIVLLVSFFSLGFRTGLVVAFSIP 368
+LP +K+ +SD+ ++ S+++ +++ ++V+++ F ++ ++P
Sbjct 317 TESLPKSVKVTVLSDRTTNIRASVNDTQFELMMAIALVVMIIYLFLRNIPATIIPGVAVP 376
Query 369 LVLAMTFAGMHIFDVGLHKISLGALILALGLLVDDAIIAVEMMAIKMEQGYSRLKAAGFA 428
L L TFA M D ++ ++L AL +A G +VDDAI+ +E ++ +E+G L AA
Sbjct 377 LSLIGTFAVMVFLDFSINNLTLMALTIATGFVVDDAIVVIENISRYIEKGEKPLAAALKG 436
Query 429 WKSTAFPMLTGTLITAAGFLPIATANSSTGEYTRSIFQVVTIALIVSWVAAVLFVPYLGE 488
F +++ T A +P+ G R + +A+++S V ++ P +
Sbjct 437 AGEIGFTIISLTFSLIAVLIPLLFMGDIVGRLFREFAITLAVAILISAVVSLTLTPMMCA 496
Query 489 KLLPDFNQMQQRVPWYQRIWAKLRKQPVPQ----LASYQEHHDPYQTRFYQTFRNMVEAC 544
++L + +Q + R K+ + + LA H P+ T
Sbjct 497 RMLSQESLRKQNR--FSRASEKMFDRIIAAYGRGLAKVLNH--PWLTL------------ 540
Query 545 VRYRKTVIVTTVLLFAGSLLLFKFVPQQFFPPSNRAEILVDIKLEEGASLTATEQAVKKV 604
+V ++T+LL S+LL+ F+P+ FFP + I ++ + +S Q ++V
Sbjct 541 -----SVALSTLLL---SVLLWVFIPKGFFPVQDNGIIQGTLQAPQSSSFANMAQRQRQV 592
Query 605 EHFLSQQKGIDNYVAYVGTGSPRFYLPLDQQLPQASFAQFVVLASSLEDRNEIRHSLDQQ 664
+ Q + + ++VG +D P + A+ + L++R D +
Sbjct 593 ADVILQDPAVQSLTSFVG---------VDGTNPSLNSARLQINLKPLDER-------DDR 636
Query 665 IKLLLPQARTRVSLLENGPPVGYPLQ--------------YRVSGEDQNLVREWAQKVAK 710
++ ++ + +T V + P Q + + + + W ++ +
Sbjct 637 VQKVIARLQTAVDKVPGVDLFLQPTQDLTIDTQVSRTQYQFTLQATSLDALSTWVPQLVE 696
Query 711 VIAENPNATNVHLDWGEPSKLIMLNIDQDRARQLGVSNTDLANFLNSSITGTVIDQYREK 770
+ + P ++V DW + + +N+D+D A +LG+S D+ N L ++ +I +
Sbjct 697 KLQQLPQLSDVSSDWQDQGLVAYVNVDRDSASRLGISMADVDNALYNAFGQRLISTIYTQ 756
Query 771 RELIEIRLRGDQAERVDVASLASLAIPTSHGGTVPLAQIARIEYRFEDGIIWHRDRLPTI 830
+ L + +A+L ++ + +S GG VPL+ IA+IE RF I H D+ P
Sbjct 757 ANQYRVVLEHNTENTPGLAALDTIRLTSSDGGVVPLSSIAKIEQRFAPLSINHLDQFPVT 816
Query 831 TVRADMRSQLQPATVVDQMKLQMQELRRQLPNGYLIDVGGTVEESAKGQESVNAGMPLFL 890
T+ +M V + E LP +D+ + S +S +
Sbjct 817 TISFNMPDNYSLGDAV--QAIMDTEKTLNLP----VDITTQFQGSTLAFQSALGSTVWLI 870
Query 891 AVVMTLLMVKLRSLSRAFI----VFLTAPLGLIGVTLFLLLFDKPFGFVAMLGTIALSGM 946
+ + + L L +FI + T P +G L LL+ +A++G I L G+
Sbjct 871 VAAVVAMYIVLGILYESFIHPITILSTLPTAGVGALLALLIAGSELDVIAIIGIILLIGI 930
Query 947 IMRNALILID-QIEQDVAAGHEVWTAIIDATVRRFRPILLTALAAVLAMIPLSRSIFFG- 1004
+ +NA+++ID + + G AI A + RFRPIL+T LAA+L +PL S G
Sbjct 931 VKKNAIMMIDFALAAEREQGMSPRDAIYQACLLRFRPILMTTLAALLGALPLMLSTGVGA 990
Query 1005 ----PMAVAIMGGLIVATFLTLFFLPALY 1029
P+ + ++GGL+V+ LTLF P +Y
Sbjct 991 ELRRPLGIGMVGGLVVSQVLTLFTTPVIY 1019
Score = 48.5 bits (114), Expect = 3e-08
Identities = 47/254 (19%), Positives = 106/254 (42%), Gaps = 27/254 (11%)
Query 794 LAIPTSHGGTVPLAQIARIEYRFEDGII--WHRDRLPTITVRADMRSQLQPA----TVVD 847
L I +G + L +A +E E+ + W + M Q QP + D
Sbjct 253 LIIAYQNGAPIRLGDVATVEQGAENSWLGAWANKEQAIV-----MNVQRQPGANIISTAD 307
Query 848 QMKLQMQELRRQLPNGYLIDVGGTVEESAKGQESVNAG---MPLFLAVVMTLLMVKLRSL 904
++ + +L LP + V + + + SVN + + +A+V+ ++ + LR++
Sbjct 308 SIRQMLPQLTESLPKSVKVTV--LSDRTTNIRASVNDTQFELMMAIALVVMIIYLFLRNI 365
Query 905 SRAFIVFLTAPLGLIGVTLFLLLFDKPFGFVAMLGTIALSGMIMRNALILIDQIEQDVAA 964
I + PL LIG ++ D + ++ +G ++ +A+++I+ I + +
Sbjct 366 PATIIPGVAVPLSLIGTFAVMVFLDFSINNLTLMALTIATGFVVDDAIVVIENISRYIEK 425
Query 965 GHEVWTAIIDATVRRFRPILLTALAAVLAMIPLSRSIFFGPM--------AVAIMGGLIV 1016
G + A + I+ + + +IPL +F G + A+ + +++
Sbjct 426 GEKPLAAALKGAGEIGFTIISLTFSLIAVLIPL---LFMGDIVGRLFREFAITLAVAILI 482
Query 1017 ATFLTLFFLPALYA 1030
+ ++L P + A
Sbjct 483 SAVVSLTLTPMMCA 496
>B7NCB1 Multidrug resistance protein MdtB [Escherichia coli O17:K52:H18
(strain UMN026 / ExPEC)]
Length=1040
Score = 254 bits (648), Expect = 5e-73
Identities = 231/1049 (22%), Positives = 459/1049 (44%), Gaps = 93/1049 (9%)
Query 19 LMLLLAIVGIFSYSKLSQSEDPPFTFKVMVIKTYWPGATAKEVSTLVTDRIEKELMTTGQ 78
LM+ + + GI Y L S P + + + T +PGA+ +++ VT +E++
Sbjct 26 LMVAILLAGIIGYRALPVSALPEVDYPTIQVVTLYPGASPDVMTSAVTAPLERQFGQMSG 85
Query 79 YDHIMAYSRPGESMVTFFAKDSLKSEQIPDVWYNVRKKVNDIKQELPVGVQGPFFNDEFG 138
+ + S G S++T + +L + V+ +N LP + P +
Sbjct 86 LKQMSSQSSGGASVITLQFQLTLPLDVAEQ---EVQAAINAATNLLPSDLPNPPVYSKVN 142
Query 139 DTFGNIYVL--TGEGFDYAVLKEYAD-RLQLELQRVPDVAKVELVGLQDQKIWIELSNTK 195
I L T +++ + R+ ++ ++ V V L G Q + ++L+
Sbjct 143 PADPPIMTLAVTSTAMPMTQVEDMVETRVAQKISQISGVGLVTLSGGQRPAVRVKLNAQA 202
Query 196 MAQLGVPVTAIQQALQQQNNMVSAGFFETPSDRIQVRLTGHLNRVEDLKHLPLLVGDKT- 254
+A LG+ ++ A+ N + G + PS + + + E+ + L + +
Sbjct 203 IAALGLTSETVRTAITGANVNSAKGSLDGPSRAVTLSANDQMQSAEEYRQLIIAYQNGAP 262
Query 255 IQLGEVAEIYRGFSDPAQPRMRFMG-----QNGIGIAVSMRKGGDIIALGKHLETTFSDL 309
I+LG+VA + +G + ++G + I + V + G +II+ + L
Sbjct 263 IRLGDVATVEQGAENS------WLGAWANKEQAIVMNVQRQPGANIISTADSIRQMLPQL 316
Query 310 QHTLPLGMKLEKVSDQPVAVQRSIHEF-IKVLAEAVIIVLLVSFFSLGFRTGLVVAFSIP 368
+LP +K+ +SD+ ++ S+++ +++ ++V+++ F ++ ++P
Sbjct 317 TESLPKSVKVTVLSDRTTNIRASVNDTQFELMMAIALVVMIIYLFLRNIPATIIPGVAVP 376
Query 369 LVLAMTFAGMHIFDVGLHKISLGALILALGLLVDDAIIAVEMMAIKMEQGYSRLKAAGFA 428
L L TFA M D ++ ++L AL +A G +VDDAI+ +E ++ +E+G L AA
Sbjct 377 LSLIGTFAVMVFLDFSINNLTLMALTIATGFVVDDAIVVIENISRYIEKGEKPLAAALKG 436
Query 429 WKSTAFPMLTGTLITAAGFLPIATANSSTGEYTRSIFQVVTIALIVSWVAAVLFVPYLGE 488
F +++ T A +P+ G R + +A+++S V ++ P +
Sbjct 437 AGEIGFTIISLTFSLIAVLIPLLFMGDIVGRLFREFAITLAVAILISAVVSLTLTPMMCA 496
Query 489 KLLPDFNQMQQRVPWYQRIWAKLRKQPVPQ----LASYQEHHDPYQTRFYQTFRNMVEAC 544
++L + +Q + R K+ ++ + LA H P+ T
Sbjct 497 RMLSQESLRKQNR--FSRASEKMFERIIAAYGRGLAKVLNH--PWLTL------------ 540
Query 545 VRYRKTVIVTTVLLFAGSLLLFKFVPQQFFPPSNRAEILVDIKLEEGASLTATEQAVKKV 604
+V ++T+LL S+LL+ F+P+ FFP + I ++ + +S T Q ++V
Sbjct 541 -----SVALSTLLL---SVLLWVFIPKGFFPVQDNGIIQGTLQAPQSSSFTNMAQRQRQV 592
Query 605 EHFLSQQKGIDNYVAYVGTGSPRFYLPLDQQLPQASFAQFVVLASSLEDRNEIRHSLDQQ 664
+ Q + + ++VG +D P + A+ + L++R D +
Sbjct 593 ADVILQDPAVQSLTSFVG---------VDGTNPSLNSARLQINLKPLDER-------DDR 636
Query 665 IKLLLPQARTRVSLLENGPPVGYPLQ--------------YRVSGEDQNLVREWAQKVAK 710
++ ++ + +T V + P Q + + + + W ++ +
Sbjct 637 VQKVIARLQTAVDKVPGVDLFLQPTQDLTIDTQVSRTQYQFTLQATSLDALSTWVPQLME 696
Query 711 VIAENPNATNVHLDWGEPSKLIMLNIDQDRARQLGVSNTDLANFLNSSITGTVIDQYREK 770
+ + P ++V DW + + +N+D+D A +LG++ D+ N L ++ +I +
Sbjct 697 KLQQLPQLSDVSSDWQDKGLVAYVNVDRDSASRLGINMADVDNALYNAFGQRLISTIYTQ 756
Query 771 RELIEIRLRGDQAERVDVASLASLAIPTSHGGTVPLAQIARIEYRFEDGIIWHRDRLPTI 830
+ L + +A+L ++ + +S GG VPL+ IA+IE RF I H D+ P
Sbjct 757 ANQYRVVLEHNTENTPGLAALDTIRLTSSDGGVVPLSSIAKIEQRFAPLSINHLDQFPVT 816
Query 831 TVRADMRSQLQPATVVDQMKLQMQELRRQLPNGYLIDVGGTVEESAKGQESVNAGMPLFL 890
T+ ++ V + E LP +D+ + S +S +
Sbjct 817 TISFNVPDNYSLGDAV--QAIMDTEKTLNLP----VDITTQFQGSTLAFQSALGSTVWLI 870
Query 891 AVVMTLLMVKLRSLSRAFI----VFLTAPLGLIGVTLFLLLFDKPFGFVAMLGTIALSGM 946
+ + + L L +FI + T P +G L LL+ +A++G I L G+
Sbjct 871 VAAVVAMYIVLGILYESFIHPITILSTLPTAGVGALLALLIAGSELDVIAIIGIILLIGI 930
Query 947 IMRNALILID-QIEQDVAAGHEVWTAIIDATVRRFRPILLTALAAVLAMIPLSRSIFFG- 1004
+ +NA+++ID + + G AI A + RFRPIL+T LAA+L +PL S G
Sbjct 931 VKKNAIMMIDFALAAEREQGMSPRDAIYQACLLRFRPILMTTLAALLGALPLMLSTGVGA 990
Query 1005 ----PMAVAIMGGLIVATFLTLFFLPALY 1029
P+ + ++GGLIV+ LTLF P +Y
Sbjct 991 ELRRPLGIGMVGGLIVSQVLTLFTTPVIY 1019
>B7NQB1 Multidrug resistance protein MdtB [Escherichia coli O7:K1
(strain IAI39 / ExPEC)]
Length=1040
Score = 254 bits (648), Expect = 5e-73
Identities = 231/1049 (22%), Positives = 457/1049 (44%), Gaps = 93/1049 (9%)
Query 19 LMLLLAIVGIFSYSKLSQSEDPPFTFKVMVIKTYWPGATAKEVSTLVTDRIEKELMTTGQ 78
LM+ + + GI Y L S P + + + T +PGA+ +++ VT +E++
Sbjct 26 LMVAILLAGIIGYRALPVSALPEVDYPTIQVVTLYPGASPDVMTSAVTAPLERQFGQMSG 85
Query 79 YDHIMAYSRPGESMVTFFAKDSLKSEQIPDVWYNVRKKVNDIKQELPVGVQGPFFNDEFG 138
+ + S G S++T + +L + V+ +N LP + P +
Sbjct 86 LKQMSSQSSGGASVITLQFQLTLPLDVAEQ---EVQAAINAATNLLPSDLPNPPVYSKVN 142
Query 139 DTFGNIYVL--TGEGFDYAVLKEYAD-RLQLELQRVPDVAKVELVGLQDQKIWIELSNTK 195
I L T +++ + R+ ++ ++ V V L G Q + ++L+
Sbjct 143 PADPPIMTLAVTSTAMPMTQVEDMVETRVAQKISQISGVGLVTLSGGQRPAVRVKLNAQA 202
Query 196 MAQLGVPVTAIQQALQQQNNMVSAGFFETPSDRIQVRLTGHLNRVEDLKHLPLLVGDKT- 254
+A LG+ ++ A+ N + G + PS + + + E+ + L + +
Sbjct 203 IAALGLTSETVRTAITGANVNSAKGSLDGPSRAVTLSANDQMQSAEEYRQLIIAYQNSAP 262
Query 255 IQLGEVAEIYRGFSDPAQPRMRFMG-----QNGIGIAVSMRKGGDIIALGKHLETTFSDL 309
I+LG+VA + +G + ++G + I + V + G +II+ + L
Sbjct 263 IRLGDVATVEQGAENS------WLGAWANKEQAIVMNVQRQPGANIISTADSIRQMLPQL 316
Query 310 QHTLPLGMKLEKVSDQPVAVQRSIHEF-IKVLAEAVIIVLLVSFFSLGFRTGLVVAFSIP 368
+LP +K+ +SD+ ++ S+ + +++ ++V+++ F ++ ++P
Sbjct 317 TESLPKSVKVTVLSDRTTNIRASVDDTQFELMMAIALVVMIIYLFLRNIPATIIPGVAVP 376
Query 369 LVLAMTFAGMHIFDVGLHKISLGALILALGLLVDDAIIAVEMMAIKMEQGYSRLKAAGFA 428
L L TFA M D ++ ++L AL +A G +VDDAI+ +E ++ +E+G L AA
Sbjct 377 LSLIGTFAVMVFLDFSINNLTLMALTIATGFVVDDAIVVIENISRYIEKGEKPLAAALKG 436
Query 429 WKSTAFPMLTGTLITAAGFLPIATANSSTGEYTRSIFQVVTIALIVSWVAAVLFVPYLGE 488
F +++ T A +P+ G R + +A+++S V ++ P +
Sbjct 437 AGEIGFTIISLTFSLIAVLIPLLFMGDIVGRLFREFAITLAVAILISAVVSLTLTPMMCA 496
Query 489 KLLPDFNQMQQRVPWYQRIWAKLRKQPVPQ----LASYQEHHDPYQTRFYQTFRNMVEAC 544
++L + +Q + R K+ + + LA H P+ T
Sbjct 497 RMLSQESLRKQNR--FSRASEKMFDRIIAAYGRGLAKVLNH--PWLTL------------ 540
Query 545 VRYRKTVIVTTVLLFAGSLLLFKFVPQQFFPPSNRAEILVDIKLEEGASLTATEQAVKKV 604
+V ++T+LL S+LL+ F+P+ FFP + I ++ + +S T Q ++V
Sbjct 541 -----SVALSTLLL---SVLLWVFIPKGFFPVQDNGIIQGTLQAPQSSSFTNMAQRQRQV 592
Query 605 EHFLSQQKGIDNYVAYVGTGSPRFYLPLDQQLPQASFAQFVVLASSLEDRNEIRHSLDQQ 664
+ Q + + ++VG +D P + A+ + L++R D +
Sbjct 593 ADVILQDPAVQSLTSFVG---------VDGTNPSLNSARLQINLKPLDER-------DDR 636
Query 665 IKLLLPQARTRVSLLENGPPVGYPLQ--------------YRVSGEDQNLVREWAQKVAK 710
++ ++ + +T V + P Q + + + + W ++ +
Sbjct 637 VQKVIARLQTAVDKVPGVDLFLQPTQDLTIDTQVSRTQYQFTLQATSLDALSTWVPQLVE 696
Query 711 VIAENPNATNVHLDWGEPSKLIMLNIDQDRARQLGVSNTDLANFLNSSITGTVIDQYREK 770
+ + P ++V DW + + +N+D+D A +LG+S D+ N L ++ +I +
Sbjct 697 KLQQLPQLSDVSSDWQDKGLVAYVNVDRDSASRLGISMADVDNALYNAFGQRLISTIYTQ 756
Query 771 RELIEIRLRGDQAERVDVASLASLAIPTSHGGTVPLAQIARIEYRFEDGIIWHRDRLPTI 830
+ L + +A+L ++ + +S GG VPL+ IA+IE RF I H D+ P
Sbjct 757 ANQYRVVLEHNTENTPGLAALDTIRLTSSDGGVVPLSSIAKIEQRFAPLSINHLDQFPVT 816
Query 831 TVRADMRSQLQPATVVDQMKLQMQELRRQLPNGYLIDVGGTVEESAKGQESVNAGMPLFL 890
T+ ++ V + E LP +D+ + S +S +
Sbjct 817 TISFNVPDNYSLGDAV--QAIMDTEKTLNLP----VDITTQFQGSTLAFQSALGSTVWLI 870
Query 891 AVVMTLLMVKLRSLSRAFI----VFLTAPLGLIGVTLFLLLFDKPFGFVAMLGTIALSGM 946
+ + + L L +FI + T P +G L L++ +A++G I L G+
Sbjct 871 VAAVVAMYIVLGILYESFIHPITILSTLPTAGVGALLALMIAGSELDVIAIIGIILLIGI 930
Query 947 IMRNALILID-QIEQDVAAGHEVWTAIIDATVRRFRPILLTALAAVLAMIPLSRSIFFG- 1004
+ +NA+++ID + + G AI A + RFRPIL+T LAA+L +PL S G
Sbjct 931 VKKNAIMMIDFALAAEREQGMSPRDAIYQACLLRFRPILMTTLAALLGALPLMLSTGVGA 990
Query 1005 ----PMAVAIMGGLIVATFLTLFFLPALY 1029
P+ + ++GGLIV+ LTLF P +Y
Sbjct 991 ELRRPLGIGMVGGLIVSQVLTLFTTPVIY 1019
Score = 45.8 bits (107), Expect = 2e-07
Identities = 43/252 (17%), Positives = 102/252 (40%), Gaps = 23/252 (9%)
Query 794 LAIPTSHGGTVPLAQIARIEYRFEDGII--WHRDRLPTITVRADMRSQLQPA----TVVD 847
L I + + L +A +E E+ + W + M Q QP + D
Sbjct 253 LIIAYQNSAPIRLGDVATVEQGAENSWLGAWANKEQAIV-----MNVQRQPGANIISTAD 307
Query 848 QMKLQMQELRRQLPNGYLIDVGGTVEESAKGQ-ESVNAGMPLFLAVVMTLLMVKLRSLSR 906
++ + +L LP + V + + + + + +A+V+ ++ + LR++
Sbjct 308 SIRQMLPQLTESLPKSVKVTVLSDRTTNIRASVDDTQFELMMAIALVVMIIYLFLRNIPA 367
Query 907 AFIVFLTAPLGLIGVTLFLLLFDKPFGFVAMLGTIALSGMIMRNALILIDQIEQDVAAGH 966
I + PL LIG ++ D + ++ +G ++ +A+++I+ I + + G
Sbjct 368 TIIPGVAVPLSLIGTFAVMVFLDFSINNLTLMALTIATGFVVDDAIVVIENISRYIEKGE 427
Query 967 EVWTAIIDATVRRFRPILLTALAAVLAMIPLSRSIFFGPM--------AVAIMGGLIVAT 1018
+ A + I+ + + +IPL +F G + A+ + ++++
Sbjct 428 KPLAAALKGAGEIGFTIISLTFSLIAVLIPL---LFMGDIVGRLFREFAITLAVAILISA 484
Query 1019 FLTLFFLPALYA 1030
++L P + A
Sbjct 485 VVSLTLTPMMCA 496
>B7UTB3 Multidrug resistance protein MdtB [Escherichia coli O127:H6
(strain E2348/69 / EPEC)]
Length=1040
Score = 253 bits (645), Expect = 1e-72
Identities = 231/1049 (22%), Positives = 457/1049 (44%), Gaps = 93/1049 (9%)
Query 19 LMLLLAIVGIFSYSKLSQSEDPPFTFKVMVIKTYWPGATAKEVSTLVTDRIEKELMTTGQ 78
LM+ + + GI Y L S P + + + T +PGA+ +++ VT +E++
Sbjct 26 LMVAILLAGIIGYQALPVSALPEVDYPTIQVVTLYPGASPDVMTSAVTAPLERQFGQMSG 85
Query 79 YDHIMAYSRPGESMVTFFAKDSLKSEQIPDVWYNVRKKVNDIKQELPVGVQGPFFNDEFG 138
+ + S G S++T + +L + V+ +N LP + P +
Sbjct 86 LKQMSSQSSGGASVITLQFQLTLPLDVAEQ---EVQAAINAATNLLPSDLPNPPVYSKVN 142
Query 139 DTFGNIYVL--TGEGFDYAVLKEYAD-RLQLELQRVPDVAKVELVGLQDQKIWIELSNTK 195
I L T +++ + R+ ++ ++ V V L G Q + ++L+
Sbjct 143 PADPPIMTLAVTSTAMPMTQVEDMVETRVAQKISQISGVGLVTLSGGQRPAVRVKLNAQA 202
Query 196 MAQLGVPVTAIQQALQQQNNMVSAGFFETPSDRIQVRLTGHLNRVEDLKHLPLLVGDKT- 254
+A LG+ ++ A+ N + G + PS + + + E+ + L + +
Sbjct 203 IAALGLTSETVRTAITGANVNSAKGSLDGPSRAVTLSANDQMQSAEEYRQLIIAYQNGAP 262
Query 255 IQLGEVAEIYRGFSDPAQPRMRFMG-----QNGIGIAVSMRKGGDIIALGKHLETTFSDL 309
I+LG+VA + +G + ++G + I + V + G +II+ + L
Sbjct 263 IRLGDVATVEQGAENS------WLGAWANKEQAIVMNVQRQPGANIISTADSIRQMLPQL 316
Query 310 QHTLPLGMKLEKVSDQPVAVQRSIHEF-IKVLAEAVIIVLLVSFFSLGFRTGLVVAFSIP 368
+LP +K+ +SD+ ++ S+ + +++ ++V+++ F ++ ++P
Sbjct 317 TESLPKSVKVTVLSDRTTNIRASVDDTQFELMMAIALVVMIIYLFLRNIPATIIPGVAVP 376
Query 369 LVLAMTFAGMHIFDVGLHKISLGALILALGLLVDDAIIAVEMMAIKMEQGYSRLKAAGFA 428
L L TFA M D ++ ++L AL +A G +VDDAI+ +E ++ +E+G L AA
Sbjct 377 LSLIGTFAVMVFLDFSINNLTLMALTIATGFVVDDAIVVIENISRYIEKGEKPLAAALKG 436
Query 429 WKSTAFPMLTGTLITAAGFLPIATANSSTGEYTRSIFQVVTIALIVSWVAAVLFVPYLGE 488
F +++ T A +P+ G R + +A+++S V ++ P +
Sbjct 437 AGEIGFTIISLTFSLIAVLIPLLFMGDIVGRLFREFAITLAVAILISAVVSLTLTPMMCA 496
Query 489 KLLPDFNQMQQRVPWYQRIWAKLRKQPVPQ----LASYQEHHDPYQTRFYQTFRNMVEAC 544
++L + +Q + R K+ ++ + LA H P+ T
Sbjct 497 RMLSQESLRKQNR--FSRASEKMFERIIAAYGQGLAKVLNH--PWLTL------------ 540
Query 545 VRYRKTVIVTTVLLFAGSLLLFKFVPQQFFPPSNRAEILVDIKLEEGASLTATEQAVKKV 604
+V ++T+LL S+LL+ F+P+ FFP + I ++ + +S Q ++V
Sbjct 541 -----SVALSTLLL---SVLLWVFIPKGFFPVQDNGIIQGTLQAPQSSSFANMAQRQRQV 592
Query 605 EHFLSQQKGIDNYVAYVGTGSPRFYLPLDQQLPQASFAQFVVLASSLEDRNEIRHSLDQQ 664
+ Q + + ++VG +D P + A+ + L++R D +
Sbjct 593 ADVILQDPAVQSLTSFVG---------VDGTNPSLNSARLQINLKPLDER-------DDR 636
Query 665 IKLLLPQARTRVSLLENGPPVGYPLQ--------------YRVSGEDQNLVREWAQKVAK 710
++ ++ + +T V + P Q + + + + W ++ +
Sbjct 637 VQKVIARLQTAVDKVPGVDLFLQPTQDLTIDTQVSRTQYQFTLQATSLDALSTWVPQLME 696
Query 711 VIAENPNATNVHLDWGEPSKLIMLNIDQDRARQLGVSNTDLANFLNSSITGTVIDQYREK 770
+ + P ++V DW + + +N+D+D A +LG+S D+ N L ++ +I +
Sbjct 697 KLQQLPQLSDVSSDWQDKGLVAYVNVDRDSASRLGISMADVDNALYNAFGQRLISTIYTQ 756
Query 771 RELIEIRLRGDQAERVDVASLASLAIPTSHGGTVPLAQIARIEYRFEDGIIWHRDRLPTI 830
+ L + +A+L ++ + +S GG VPL+ IA+IE RF I H D+ P
Sbjct 757 ANQYRVVLEHNTENTPGLAALDTIRLTSSDGGVVPLSSIAKIEQRFAPLSINHLDQFPVT 816
Query 831 TVRADMRSQLQPATVVDQMKLQMQELRRQLPNGYLIDVGGTVEESAKGQESVNAGMPLFL 890
T+ ++ V + E LP +D+ + S +S +
Sbjct 817 TISFNVPDNYSLGDAV--QAIMDTEKTLNLP----VDITTQFQGSTLAFQSALGSTVWLI 870
Query 891 AVVMTLLMVKLRSLSRAFI----VFLTAPLGLIGVTLFLLLFDKPFGFVAMLGTIALSGM 946
+ + + L L +FI + T P +G L LL+ +A++G I L G+
Sbjct 871 VAAVVAMYIVLGILYESFIHPITILSTLPTAGVGALLALLIAGSELDVIAIIGIILLIGI 930
Query 947 IMRNALILID-QIEQDVAAGHEVWTAIIDATVRRFRPILLTALAAVLAMIPLSRSIFFG- 1004
+ +NA+++ID + + G AI A + RFRPIL+T LAA+L +PL S G
Sbjct 931 VKKNAIMMIDFALAAEREQGMSPRDAIYQACLLRFRPILMTTLAALLGALPLMLSTGVGA 990
Query 1005 ----PMAVAIMGGLIVATFLTLFFLPALY 1029
P+ + ++GGLIV+ LTLF P +Y
Sbjct 991 ELRRPLGIGMVGGLIVSQVLTLFTTPVIY 1019
>Q7N3E1 Multidrug resistance protein MdtC [Photorhabdus laumondii
subsp. laumondii (strain DSM 15139 / CIP 105565 / TT01)]
Length=1036
Score = 252 bits (644), Expect = 2e-72
Identities = 229/1047 (22%), Positives = 478/1047 (46%), Gaps = 74/1047 (7%)
Query 19 LMLLLAIVGIFSYSKLSQSEDPPFTFKVMVIKTYWPGATAKEVSTLVTDRIEKELMTTGQ 78
L L + + G+ ++ L S P F V+ + PGA+ + +++ V +E L
Sbjct 17 LSLAITLCGVLGFTLLPVSPLPQVDFPVISVYASLPGASPETMASSVATPLEHALGRIAG 76
Query 79 YDHIMAYSRPGESMVTFFAKDSLKSEQIPDVWYNVRKKVNDIKQELPVGVQGP--FFNDE 136
+ + + S G + +T + + I +V+ +N + LP G+ ++
Sbjct 77 VNEMTSSSSLGSTNITL---EFDLNRDINSAARDVQAALNAAQSLLPSGMPSRPHYYKVN 133
Query 137 FGDTFGNIYVLTGEGFDYAVLKEYAD-RLQLELQRVPDVAKVELVGLQDQKIWIELSNTK 195
D I LT + ++ L ++A +L ++ +V V++V + G + +EL+
Sbjct 134 PTDAPIMILTLTSDTYNQGQLYDFASTQLAQKIAQVEGVSEVSVGGSSLPAVRVELNPGV 193
Query 196 MAQLGVPVTAIQQALQQQNNMVSAGFFETPSDRIQVRLTGHLNRVEDLKHLPLLV---GD 252
+ GV + A+++A+ N G+ ++ Q+++ L E+ + P++V +
Sbjct 194 LFHQGVSLDAVRKAISNANVRRPQGYVDSEQQHWQIQMNDELKTAENYR--PIIVHYNNN 251
Query 253 KTIQLGEVAEIYRGFSDPAQPRMRFMGQNGIGIAVSMRKGGDIIALGKHLETTFSDLQHT 312
++L +VA + + M G+ I + + G +IIA + L +
Sbjct 252 SPVRLQDVANVKDSVQNVRAAGMSG-GEPAILLIIRREAGANIIATVNRIREQLPALHES 310
Query 313 LPLGMKLEKVSDQPVAVQRSIHEFIKVLAEAVIIVLLVSFFSL-GFRTGLVVAFSIPLVL 371
+P ++L+ D+ ++ SI E + L A+ +V+LV F L R L+ A ++P+ L
Sbjct 311 IPASIQLKVAQDRTPTIRASIVEVERALVIAIGLVILVVFLFLRSGRATLIPAIAVPVSL 370
Query 372 AMTFAGMHIFDVGLHKISLGALILALGLLVDDAIIAVEMMAIKMEQGYSRLKAAGFAWKS 431
TF M++ L+ +SL AL +A G +VDDAI+ +E ++ +E G ++AA +
Sbjct 371 IGTFTAMYLCGFSLNNLSLMALTVATGFVVDDAIVVLENISRHLEAGIKPMQAALQGVRE 430
Query 432 TAFPMLTGTLITAAGFLPIATANSSTGEYTRSIFQVVTIALIVSWVAAVLFVPYLGEKLL 491
F +L+ ++ A F+P+ + G R +T ++ +S + ++ P + LL
Sbjct 431 VGFTVLSMSISLVAVFIPLLLMDGLVGRLFREFAITLTTSISISLLVSLTLTPMMCAHLL 490
Query 492 PDFN-QMQQRVPWYQRIWAKLRKQPVPQLASYQEHHDPYQTRFYQTFRNMVEACVRYRKT 550
+ Q+++ + ++ K++ Q + + + + +
Sbjct 491 KSQRPKAQKKIRGFGKVLLKIQ----------------------QVYGRSLMWVLNHSRW 528
Query 551 VIVTTVLLFAGSLLLFKFVPQQFFPPSNRAEILVDIKLEEGASLTATEQAVKKVEHFLSQ 610
V++ + A ++ L+ +P+ FFP + +L ++ ++ S + + +K ++
Sbjct 529 VLLILAGIIALNVWLYINIPKTFFPEQDTGRLLGFVRADQSISFQSMREKMKNFMQTINA 588
Query 611 QKGIDNYVAYVGTGSPR---FYLPLDQQLPQASFAQFVVLASSLEDRNEIRHSLDQQIKL 667
+D+ + + G G ++ L ++ A+ ++ ++ NE +L
Sbjct 589 DPTVDSVIGFTGGGRVNNGFMFISLKPLKERSENAEQIISRLRIKLANEPGANL-----F 643
Query 668 LLPQARTRVSLLENGPPVGYPLQYRVSGEDQNLVREWAQKVAKVIAENPNATNVHLDWGE 727
L+P R G Q+ + +D N +R+W + K + + P T+V+ D +
Sbjct 644 LIPVQDIRA----GGRQANASYQFTLLADDLNDLRKWEPVIRKALGQLPQLTDVNSDKED 699
Query 728 PSKLIMLNIDQDRARQLGVSNTDLANFLNSSI----TGTVIDQYREKRELIEIRLRGDQA 783
+ + D+D +LG++ ++ N LN++ T+ + + ++E+ Q
Sbjct 700 KGAEMAIIYDRDTMSRLGINVSEANNLLNNAFGQRQISTIYQPLNQYKVVMEVAPEYTQ- 758
Query 784 ERVDVASLASLAIPTSHGGTVPLAQIARIEYRFEDGIIWHRDRLPTITVRADMRSQLQPA 843
DV++L + + + G +PL+ A + + H+ T+ ++ +
Sbjct 759 ---DVSALEKMFVINNQGKAIPLSYFAHWQPANAPLSVNHQGLSAASTIAFNVPEGYTLS 815
Query 844 TVVDQMKLQMQELRRQLPNGYLIDVGGTVEESAK-GQESVNAGMPLFLAVVMTLLMVKLR 902
++ ++ ELR +P+ V GT +A+ QE++ + + L LA ++T+ +V L
Sbjct 816 DAINAIERTTTELR--VPS----TVRGTFAGTAQIFQETLKSQLFLILAAIITVYLV-LG 868
Query 903 SLSRAFI----VFLTAPLGLIGVTLFLLLFDKPFGFVAMLGTIALSGMIMRNALILID-Q 957
L ++I + T P IG L L LFD PF +A++G + L G++ +NA+I++D
Sbjct 869 ILYESYIHPLTILSTLPSAGIGALLALELFDTPFSLIALIGIMLLIGIVKKNAIIMVDFA 928
Query 958 IEQDVAAGHEVWTAIIDATVRRFRPILLTALAAVLAMIPLSRSIFFG-----PMAVAIMG 1012
IE AI A++ RFRPIL+T LAA+ +PL S G P+ + I+G
Sbjct 929 IEAQRNGNICARDAIFQASLLRFRPILMTTLAALFGSLPLVLSSGDGTELRQPLGITIVG 988
Query 1013 GLIVATFLTLFFLPALYAAWFKVKKTP 1039
GL+++ LTL+ P +Y + +++ P
Sbjct 989 GLVMSQLLTLYTTPVVYLCFDRLRAYP 1015
>Q3Z0C9 Multidrug resistance protein MdtB [Shigella sonnei (strain
Ss046)]
Length=1040
Score = 252 bits (644), Expect = 2e-72
Identities = 230/1049 (22%), Positives = 458/1049 (44%), Gaps = 93/1049 (9%)
Query 19 LMLLLAIVGIFSYSKLSQSEDPPFTFKVMVIKTYWPGATAKEVSTLVTDRIEKELMTTGQ 78
LM+ + + GI Y L S P + + + T +PGA+ +++ VT +E++
Sbjct 26 LMVAILLAGIIGYRALPVSALPEVDYPTIQVVTLYPGASPDVMTSAVTAPLERQFGQMSG 85
Query 79 YDHIMAYSRPGESMVTFFAKDSLKSEQIPDVWYNVRKKVNDIKQELPVGVQGPFFNDEFG 138
+ + S G S++T + +L + V+ +N LP + P +
Sbjct 86 LKQMSSQSSGGASVITLQFQLTLPLDVAEQ---EVQAAINAATNLLPSDLPNPPVYSKVN 142
Query 139 DTFGNIYVL--TGEGFDYAVLKEYAD-RLQLELQRVPDVAKVELVGLQDQKIWIELSNTK 195
I L T +++ + R+ ++ ++ V V L G Q + ++L+
Sbjct 143 PADPPIMTLAVTSTAMPMTQVEDMVETRVAQKISQISGVGLVTLSGGQRPAVRVKLNAQA 202
Query 196 MAQLGVPVTAIQQALQQQNNMVSAGFFETPSDRIQVRLTGHLNRVEDLKHLPLLVGDKT- 254
+A LG+ ++ A+ N + G + PS + + + E+ + L + +
Sbjct 203 IAALGLTSETVRTAITGANVNSAKGSLDGPSRAVTLSANDQMQSAEEYRQLIIAYQNGAP 262
Query 255 IQLGEVAEIYRGFSDPAQPRMRFMG-----QNGIGIAVSMRKGGDIIALGKHLETTFSDL 309
I+LG+VA + +G + ++G + I + V + G +II+ + L
Sbjct 263 IRLGDVATVEQGAENS------WLGAWANKEQAIVMNVQRQPGANIISTADSIRQMLPQL 316
Query 310 QHTLPLGMKLEKVSDQPVAVQRSIHEF-IKVLAEAVIIVLLVSFFSLGFRTGLVVAFSIP 368
+LP +K+ +SD+ ++ S+ + +++ ++V+++ F ++ ++P
Sbjct 317 TESLPKSVKVTVLSDRTTNIRASVDDTQFELMMAIALVVMIIYLFLRNIPATIIPGVAVP 376
Query 369 LVLAMTFAGMHIFDVGLHKISLGALILALGLLVDDAIIAVEMMAIKMEQGYSRLKAAGFA 428
L L TFA M D ++ ++L AL +A G +VDDAI+ +E ++ +E+G L AA
Sbjct 377 LSLIGTFAVMVFLDFSINNLTLMALTIATGFVVDDAIVVIENISRYIEKGEKPLAAALKG 436
Query 429 WKSTAFPMLTGTLITAAGFLPIATANSSTGEYTRSIFQVVTIALIVSWVAAVLFVPYLGE 488
F +++ T A +P+ G R + +A+++S V ++ P +
Sbjct 437 AGEIGFTIISLTFSLIAVLIPLLFMGDIVGRLFREFAITLAVAILISAVVSLTLTPMMCA 496
Query 489 KLLPDFNQMQQRVPWYQRIWAKLRKQPVPQ----LASYQEHHDPYQTRFYQTFRNMVEAC 544
++L + +Q + R K+ + + LA H P+ T
Sbjct 497 RMLSQESLRKQNR--FSRASEKMFDRIIAAYGRGLAKVLNH--PWLTL------------ 540
Query 545 VRYRKTVIVTTVLLFAGSLLLFKFVPQQFFPPSNRAEILVDIKLEEGASLTATEQAVKKV 604
+V ++T+LL S+LL+ F+P+ FFP + I ++ + +S T Q ++V
Sbjct 541 -----SVALSTLLL---SVLLWVFIPKGFFPVQDNGIIQGTLQAPQSSSFTNMAQRQRQV 592
Query 605 EHFLSQQKGIDNYVAYVGTGSPRFYLPLDQQLPQASFAQFVVLASSLEDRNEIRHSLDQQ 664
+ Q + + ++VG +D P + A+ + L++R D +
Sbjct 593 ADVILQDPAVQSLTSFVG---------VDGTNPSLNSARLQINLKPLDER-------DDR 636
Query 665 IKLLLPQARTRVSLLENGPPVGYPLQ--------------YRVSGEDQNLVREWAQKVAK 710
++ ++ + +T V + P Q + + + + W ++ +
Sbjct 637 VQKVIARLQTAVDKVPGVDLFLQPTQDLTIDTQVSRTQYQFTLQATSLDALSTWVPQLME 696
Query 711 VIAENPNATNVHLDWGEPSKLIMLNIDQDRARQLGVSNTDLANFLNSSITGTVIDQYREK 770
+ + P ++V DW + + +N+D+D A +LG+S D+ N L ++ +I +
Sbjct 697 KLQQLPQLSDVSSDWQDQGLVAYVNVDRDSASRLGISMADVDNALYNAFGQRLISTIYTQ 756
Query 771 RELIEIRLRGDQAERVDVASLASLAIPTSHGGTVPLAQIARIEYRFEDGIIWHRDRLPTI 830
+ L + +A+L ++ + +S GG VPL+ IA++E RF I H D+ P
Sbjct 757 ANQYRVVLEHNTEITPGLAALDTIRLTSSDGGVVPLSSIAKVEQRFAPLSINHLDQFPVT 816
Query 831 TVRADMRSQLQPATVVDQMKLQMQELRRQLPNGYLIDVGGTVEESAKGQESVNAGMPLFL 890
T+ ++ V + + E LP +D+ + S +S +
Sbjct 817 TISFNVPDNYSLGDAVQE--IMDTEKTLNLP----VDITTQFQGSTLAFQSALGSTVWLI 870
Query 891 AVVMTLLMVKLRSLSRAFI----VFLTAPLGLIGVTLFLLLFDKPFGFVAMLGTIALSGM 946
+ + + L L +FI + T P +G L L++ +A++G I L G+
Sbjct 871 VAAVVAMYIVLGILYESFIHPITILSTLPTAGVGALLALMIAGSELDVIAIIGIILLIGI 930
Query 947 IMRNALILID-QIEQDVAAGHEVWTAIIDATVRRFRPILLTALAAVLAMIPLSRSIFFG- 1004
+ +NA+++ID + + G AI A + RFRPIL+T LAA+L +PL S G
Sbjct 931 VKKNAIMMIDFALAAEREQGMSPRDAIYQACLLRFRPILMTTLAALLGALPLMLSTGVGA 990
Query 1005 ----PMAVAIMGGLIVATFLTLFFLPALY 1029
P+ + ++GGLIV+ LTLF P +Y
Sbjct 991 ELRRPLGIGMVGGLIVSQVLTLFTTPVIY 1019
Score = 48.1 bits (113), Expect = 5e-08
Identities = 44/252 (17%), Positives = 103/252 (41%), Gaps = 23/252 (9%)
Query 794 LAIPTSHGGTVPLAQIARIEYRFEDGII--WHRDRLPTITVRADMRSQLQPA----TVVD 847
L I +G + L +A +E E+ + W + M Q QP + D
Sbjct 253 LIIAYQNGAPIRLGDVATVEQGAENSWLGAWANKEQAIV-----MNVQRQPGANIISTAD 307
Query 848 QMKLQMQELRRQLPNGYLIDVGGTVEESAKGQ-ESVNAGMPLFLAVVMTLLMVKLRSLSR 906
++ + +L LP + V + + + + + +A+V+ ++ + LR++
Sbjct 308 SIRQMLPQLTESLPKSVKVTVLSDRTTNIRASVDDTQFELMMAIALVVMIIYLFLRNIPA 367
Query 907 AFIVFLTAPLGLIGVTLFLLLFDKPFGFVAMLGTIALSGMIMRNALILIDQIEQDVAAGH 966
I + PL LIG ++ D + ++ +G ++ +A+++I+ I + + G
Sbjct 368 TIIPGVAVPLSLIGTFAVMVFLDFSINNLTLMALTIATGFVVDDAIVVIENISRYIEKGE 427
Query 967 EVWTAIIDATVRRFRPILLTALAAVLAMIPLSRSIFFGPM--------AVAIMGGLIVAT 1018
+ A + I+ + + +IPL +F G + A+ + ++++
Sbjct 428 KPLAAALKGAGEIGFTIISLTFSLIAVLIPL---LFMGDIVGRLFREFAITLAVAILISA 484
Query 1019 FLTLFFLPALYA 1030
++L P + A
Sbjct 485 VVSLTLTPMMCA 496
>B7L9U8 Multidrug resistance protein MdtB [Escherichia coli (strain
55989 / EAEC)]
Length=1040
Score = 252 bits (643), Expect = 2e-72
Identities = 231/1049 (22%), Positives = 456/1049 (43%), Gaps = 93/1049 (9%)
Query 19 LMLLLAIVGIFSYSKLSQSEDPPFTFKVMVIKTYWPGATAKEVSTLVTDRIEKELMTTGQ 78
LM+ + + GI Y L S P + + + T +PGA+ +++ VT +E++
Sbjct 26 LMVAILLAGIIGYRALPVSALPEVDYPTIQVVTLYPGASPDVMTSAVTAPLERQFGQMSG 85
Query 79 YDHIMAYSRPGESMVTFFAKDSLKSEQIPDVWYNVRKKVNDIKQELPVGVQGPFFNDEFG 138
+ + S G S++T + +L + V+ +N LP + P +
Sbjct 86 LKQMSSQSSGGASVITLQFQLTLPLDVAEQ---EVQAAINAATNLLPSDLPNPPVYSKVN 142
Query 139 DTFGNIYVL--TGEGFDYAVLKEYAD-RLQLELQRVPDVAKVELVGLQDQKIWIELSNTK 195
I L T +++ + R+ ++ ++ V V L G Q + ++L+
Sbjct 143 PADPPIMTLAVTSTAMPMTQVEDMVETRVAQKISQISGVGLVTLSGGQRPAVRVKLNAQA 202
Query 196 MAQLGVPVTAIQQALQQQNNMVSAGFFETPSDRIQVRLTGHLNRVEDLKHLPLLVGDKT- 254
+A LG+ ++ A+ N + G + PS + + + E+ + L + +
Sbjct 203 IAALGLTSETVRTAITGANVNSAKGSLDGPSRAVTLSANDQMQSAEEYRQLIIAYQNGAP 262
Query 255 IQLGEVAEIYRGFSDPAQPRMRFMG-----QNGIGIAVSMRKGGDIIALGKHLETTFSDL 309
I+LG+VA + +G + ++G + I + V + G +II+ + L
Sbjct 263 IRLGDVATVEQGAENS------WLGAWANKEQAIVMNVQRQPGANIISTADSIRQMLPQL 316
Query 310 QHTLPLGMKLEKVSDQPVAVQRSIHEF-IKVLAEAVIIVLLVSFFSLGFRTGLVVAFSIP 368
+LP +K+ +SD+ ++ S+ + +++ ++V+++ F ++ ++P
Sbjct 317 TESLPKSVKVTVLSDRTTNIRASVDDTQFELMMAIALVVMIIYLFLRNIPATIIPGVAVP 376
Query 369 LVLAMTFAGMHIFDVGLHKISLGALILALGLLVDDAIIAVEMMAIKMEQGYSRLKAAGFA 428
L L TFA M D ++ ++L AL +A G +VDDAI+ +E ++ +E+G L AA
Sbjct 377 LSLIGTFAVMVFLDFSINNLTLMALTIATGFVVDDAIVVIENISRYIEKGEKPLAAALKG 436
Query 429 WKSTAFPMLTGTLITAAGFLPIATANSSTGEYTRSIFQVVTIALIVSWVAAVLFVPYLGE 488
F +++ T A +P+ G R + +A+++S V ++ P +
Sbjct 437 AGEIGFTIISLTFSLIAVLIPLLFMGDIVGRLFREFAITLAVAILISAVVSLTLTPMMCA 496
Query 489 KLLPDFNQMQQRVPWYQRIWAKLRKQPVPQ----LASYQEHHDPYQTRFYQTFRNMVEAC 544
++L + +Q + R K+ + + LA H P+ T
Sbjct 497 RMLSQESLRKQNR--FSRASEKMFDRIIAAYGQGLAKVLNH--PWLTL------------ 540
Query 545 VRYRKTVIVTTVLLFAGSLLLFKFVPQQFFPPSNRAEILVDIKLEEGASLTATEQAVKKV 604
+V ++T+LL S+LL+ F+P+ FFP + I ++ + +S Q ++V
Sbjct 541 -----SVALSTLLL---SVLLWVFIPKGFFPVQDNGIIQGTLQAPQSSSFANMAQRQRQV 592
Query 605 EHFLSQQKGIDNYVAYVGTGSPRFYLPLDQQLPQASFAQFVVLASSLEDRNEIRHSLDQQ 664
+ Q + + ++VG +D P + A+ + LE+R D +
Sbjct 593 ADVILQDPAVQSLTSFVG---------VDGTNPSLNSARLQINLKPLEER-------DDR 636
Query 665 IKLLLPQARTRVSLLENGPPVGYPLQ--------------YRVSGEDQNLVREWAQKVAK 710
++ ++ + +T V + P Q + + + + W ++ +
Sbjct 637 VQKVIARLQTAVDKVPGVDLFLQPTQDLTIDTQVSRTQYQFTLQATSLDALSTWVPQLME 696
Query 711 VIAENPNATNVHLDWGEPSKLIMLNIDQDRARQLGVSNTDLANFLNSSITGTVIDQYREK 770
+ + P ++V DW + + +N+D+D A +LG+S D+ N L ++ +I +
Sbjct 697 KLQQLPQLSDVSSDWQDKGLVAYVNVDRDSASRLGISMADVDNALYNAFGQRLISTIYTQ 756
Query 771 RELIEIRLRGDQAERVDVASLASLAIPTSHGGTVPLAQIARIEYRFEDGIIWHRDRLPTI 830
+ L + +A+L ++ + +S GG VPL+ IA+IE RF I H D+ P
Sbjct 757 ANQYRVVLEHNTENTPGLAALDTIRLTSSDGGVVPLSSIAKIEQRFAPLSINHLDQFPVT 816
Query 831 TVRADMRSQLQPATVVDQMKLQMQELRRQLPNGYLIDVGGTVEESAKGQESVNAGMPLFL 890
T+ ++ V + E LP +D+ + S +S +
Sbjct 817 TISFNVPDNYSLGDAV--QAIMDTEKTLNLP----VDITTQFQGSTLAFQSALGSTVWLI 870
Query 891 AVVMTLLMVKLRSLSRAFI----VFLTAPLGLIGVTLFLLLFDKPFGFVAMLGTIALSGM 946
+ + + L L +FI + T P +G L L++ +A++G I L G+
Sbjct 871 VAAVVAMYIVLGILYESFIHPITILSTLPTAGVGALLALMIAGSELDVIAIIGIILLIGI 930
Query 947 IMRNALILID-QIEQDVAAGHEVWTAIIDATVRRFRPILLTALAAVLAMIPLSRSIFFG- 1004
+ +NA+++ID + + G AI A + RFRPIL+T LAA+L +PL S G
Sbjct 931 VKKNAIMMIDFALAAEREQGMSPRDAIYQACLLRFRPILMTTLAALLGALPLMLSTGVGA 990
Query 1005 ----PMAVAIMGGLIVATFLTLFFLPALY 1029
P+ + ++GGLIV+ LTLF P +Y
Sbjct 991 ELRRPLGIGMVGGLIVSQVLTLFTTPVIY 1019
Score = 48.1 bits (113), Expect = 5e-08
Identities = 44/252 (17%), Positives = 103/252 (41%), Gaps = 23/252 (9%)
Query 794 LAIPTSHGGTVPLAQIARIEYRFEDGII--WHRDRLPTITVRADMRSQLQPA----TVVD 847
L I +G + L +A +E E+ + W + M Q QP + D
Sbjct 253 LIIAYQNGAPIRLGDVATVEQGAENSWLGAWANKEQAIV-----MNVQRQPGANIISTAD 307
Query 848 QMKLQMQELRRQLPNGYLIDVGGTVEESAKGQ-ESVNAGMPLFLAVVMTLLMVKLRSLSR 906
++ + +L LP + V + + + + + +A+V+ ++ + LR++
Sbjct 308 SIRQMLPQLTESLPKSVKVTVLSDRTTNIRASVDDTQFELMMAIALVVMIIYLFLRNIPA 367
Query 907 AFIVFLTAPLGLIGVTLFLLLFDKPFGFVAMLGTIALSGMIMRNALILIDQIEQDVAAGH 966
I + PL LIG ++ D + ++ +G ++ +A+++I+ I + + G
Sbjct 368 TIIPGVAVPLSLIGTFAVMVFLDFSINNLTLMALTIATGFVVDDAIVVIENISRYIEKGE 427
Query 967 EVWTAIIDATVRRFRPILLTALAAVLAMIPLSRSIFFGPM--------AVAIMGGLIVAT 1018
+ A + I+ + + +IPL +F G + A+ + ++++
Sbjct 428 KPLAAALKGAGEIGFTIISLTFSLIAVLIPL---LFMGDIVGRLFREFAITLAVAILISA 484
Query 1019 FLTLFFLPALYA 1030
++L P + A
Sbjct 485 VVSLTLTPMMCA 496
>P76398 Multidrug resistance protein MdtB [Escherichia coli (strain
K12)]
Length=1040
Score = 251 bits (642), Expect = 3e-72
Identities = 231/1049 (22%), Positives = 456/1049 (43%), Gaps = 93/1049 (9%)
Query 19 LMLLLAIVGIFSYSKLSQSEDPPFTFKVMVIKTYWPGATAKEVSTLVTDRIEKELMTTGQ 78
LM+ + + GI Y L S P + + + T +PGA+ +++ VT +E++
Sbjct 26 LMVAILLAGIIGYRALPVSALPEVDYPTIQVVTLYPGASPDVMTSAVTAPLERQFGQMSG 85
Query 79 YDHIMAYSRPGESMVTFFAKDSLKSEQIPDVWYNVRKKVNDIKQELPVGVQGPFFNDEFG 138
+ + S G S++T + +L + V+ +N LP + P +
Sbjct 86 LKQMSSQSSGGASVITLQFQLTLPLDVAEQ---EVQAAINAATNLLPSDLPNPPVYSKVN 142
Query 139 DTFGNIYVL--TGEGFDYAVLKEYAD-RLQLELQRVPDVAKVELVGLQDQKIWIELSNTK 195
I L T +++ + R+ ++ ++ V V L G Q + ++L+
Sbjct 143 PADPPIMTLAVTSTAMPMTQVEDMVETRVAQKISQISGVGLVTLSGGQRPAVRVKLNAQA 202
Query 196 MAQLGVPVTAIQQALQQQNNMVSAGFFETPSDRIQVRLTGHLNRVEDLKHLPLLVGDKT- 254
+A LG+ ++ A+ N + G + PS + + + E+ + L + +
Sbjct 203 IAALGLTSETVRTAITGANVNSAKGSLDGPSRAVTLSANDQMQSAEEYRQLIIAYQNGAP 262
Query 255 IQLGEVAEIYRGFSDPAQPRMRFMG-----QNGIGIAVSMRKGGDIIALGKHLETTFSDL 309
I+LG+VA + +G + ++G + I + V + G +II+ + L
Sbjct 263 IRLGDVATVEQGAENS------WLGAWANKEQAIVMNVQRQPGANIISTADSIRQMLPQL 316
Query 310 QHTLPLGMKLEKVSDQPVAVQRSIHEF-IKVLAEAVIIVLLVSFFSLGFRTGLVVAFSIP 368
+LP +K+ +SD+ ++ S+ + +++ ++V+++ F ++ ++P
Sbjct 317 TESLPKSVKVTVLSDRTTNIRASVDDTQFELMMAIALVVMIIYLFLRNIPATIIPGVAVP 376
Query 369 LVLAMTFAGMHIFDVGLHKISLGALILALGLLVDDAIIAVEMMAIKMEQGYSRLKAAGFA 428
L L TFA M D ++ ++L AL +A G +VDDAI+ +E ++ +E+G L AA
Sbjct 377 LSLIGTFAVMVFLDFSINNLTLMALTIATGFVVDDAIVVIENISRYIEKGEKPLAAALKG 436
Query 429 WKSTAFPMLTGTLITAAGFLPIATANSSTGEYTRSIFQVVTIALIVSWVAAVLFVPYLGE 488
F +++ T A +P+ G R + +A+++S V ++ P +
Sbjct 437 AGEIGFTIISLTFSLIAVLIPLLFMGDIVGRLFREFAITLAVAILISAVVSLTLTPMMCA 496
Query 489 KLLPDFNQMQQRVPWYQRIWAKLRKQPVPQ----LASYQEHHDPYQTRFYQTFRNMVEAC 544
++L + +Q + R K+ + + LA H P+ T
Sbjct 497 RMLSQESLRKQNR--FSRASEKMFDRIIAAYGRGLAKVLNH--PWLTL------------ 540
Query 545 VRYRKTVIVTTVLLFAGSLLLFKFVPQQFFPPSNRAEILVDIKLEEGASLTATEQAVKKV 604
+V ++T+LL S+LL+ F+P+ FFP + I ++ + +S Q ++V
Sbjct 541 -----SVALSTLLL---SVLLWVFIPKGFFPVQDNGIIQGTLQAPQSSSFANMAQRQRQV 592
Query 605 EHFLSQQKGIDNYVAYVGTGSPRFYLPLDQQLPQASFAQFVVLASSLEDRNEIRHSLDQQ 664
+ Q + + ++VG +D P + A+ + L++R D +
Sbjct 593 ADVILQDPAVQSLTSFVG---------VDGTNPSLNSARLQINLKPLDER-------DDR 636
Query 665 IKLLLPQARTRVSLLENGPPVGYPLQ--------------YRVSGEDQNLVREWAQKVAK 710
++ ++ + +T V + P Q + + + + W ++ +
Sbjct 637 VQKVIARLQTAVDKVPGVDLFLQPTQDLTIDTQVSRTQYQFTLQATSLDALSTWVPQLME 696
Query 711 VIAENPNATNVHLDWGEPSKLIMLNIDQDRARQLGVSNTDLANFLNSSITGTVIDQYREK 770
+ + P ++V DW + + +N+D+D A +LG+S D+ N L ++ +I +
Sbjct 697 KLQQLPQLSDVSSDWQDKGLVAYVNVDRDSASRLGISMADVDNALYNAFGQRLISTIYTQ 756
Query 771 RELIEIRLRGDQAERVDVASLASLAIPTSHGGTVPLAQIARIEYRFEDGIIWHRDRLPTI 830
+ L + +A+L ++ + +S GG VPL+ IA+IE RF I H D+ P
Sbjct 757 ANQYRVVLEHNTENTPGLAALDTIRLTSSDGGVVPLSSIAKIEQRFAPLSINHLDQFPVT 816
Query 831 TVRADMRSQLQPATVVDQMKLQMQELRRQLPNGYLIDVGGTVEESAKGQESVNAGMPLFL 890
T+ ++ V + E LP +D+ + S +S +
Sbjct 817 TISFNVPDNYSLGDAV--QAIMDTEKTLNLP----VDITTQFQGSTLAFQSALGSTVWLI 870
Query 891 AVVMTLLMVKLRSLSRAFI----VFLTAPLGLIGVTLFLLLFDKPFGFVAMLGTIALSGM 946
+ + + L L +FI + T P +G L LL+ +A++G I L G+
Sbjct 871 VAAVVAMYIVLGILYESFIHPITILSTLPTAGVGALLALLIAGSELDVIAIIGIILLIGI 930
Query 947 IMRNALILID-QIEQDVAAGHEVWTAIIDATVRRFRPILLTALAAVLAMIPLSRSIFFG- 1004
+ +NA+++ID + + G AI A + RFRPIL+T LAA+L +PL S G
Sbjct 931 VKKNAIMMIDFALAAEREQGMSPREAIYQACLLRFRPILMTTLAALLGALPLMLSTGVGA 990
Query 1005 ----PMAVAIMGGLIVATFLTLFFLPALY 1029
P+ + ++GGLIV+ LTLF P +Y
Sbjct 991 ELRRPLGIGMVGGLIVSQVLTLFTTPVIY 1019
Score = 48.1 bits (113), Expect = 5e-08
Identities = 44/252 (17%), Positives = 103/252 (41%), Gaps = 23/252 (9%)
Query 794 LAIPTSHGGTVPLAQIARIEYRFEDGII--WHRDRLPTITVRADMRSQLQPA----TVVD 847
L I +G + L +A +E E+ + W + M Q QP + D
Sbjct 253 LIIAYQNGAPIRLGDVATVEQGAENSWLGAWANKEQAIV-----MNVQRQPGANIISTAD 307
Query 848 QMKLQMQELRRQLPNGYLIDVGGTVEESAKGQ-ESVNAGMPLFLAVVMTLLMVKLRSLSR 906
++ + +L LP + V + + + + + +A+V+ ++ + LR++
Sbjct 308 SIRQMLPQLTESLPKSVKVTVLSDRTTNIRASVDDTQFELMMAIALVVMIIYLFLRNIPA 367
Query 907 AFIVFLTAPLGLIGVTLFLLLFDKPFGFVAMLGTIALSGMIMRNALILIDQIEQDVAAGH 966
I + PL LIG ++ D + ++ +G ++ +A+++I+ I + + G
Sbjct 368 TIIPGVAVPLSLIGTFAVMVFLDFSINNLTLMALTIATGFVVDDAIVVIENISRYIEKGE 427
Query 967 EVWTAIIDATVRRFRPILLTALAAVLAMIPLSRSIFFGPM--------AVAIMGGLIVAT 1018
+ A + I+ + + +IPL +F G + A+ + ++++
Sbjct 428 KPLAAALKGAGEIGFTIISLTFSLIAVLIPL---LFMGDIVGRLFREFAITLAVAILISA 484
Query 1019 FLTLFFLPALYA 1030
++L P + A
Sbjct 485 VVSLTLTPMMCA 496
>P24177 Probable aminoglycoside efflux pump [Escherichia coli
(strain K12)]
Length=1037
Score = 248 bits (634), Expect = 3e-71
Identities = 244/1058 (23%), Positives = 465/1058 (44%), Gaps = 96/1058 (9%)
Query 19 LMLLLAIVGIFSYSKLSQSEDPPFTFKVMVIKTYWPGATAKEVSTLVTDRIEKELMTTGQ 78
L +LL + G + L + P + + +PGA+A+ + VT IE+ +
Sbjct 15 LAILLCLTGTLAIFSLPVEQYPDLAPPNVRVTANYPGASAQTLENTVTQVIEQNMTGLDN 74
Query 79 YDHIMAYSR-PGESMVTFFAKDSLKSEQIPD-VWYNVRKKVNDIKQELPVGVQGPFFN-D 135
++ + S G++ VT S K+ PD V+ ++ ++LP VQ
Sbjct 75 LMYMSSQSSGTGQASVTL----SFKAGTDPDEAVQQVQNQLQSAMRKLPQAVQNQGVTVR 130
Query 136 EFGDTFGNI----YVLTGEGFDYAVLKEY-ADRLQLELQRVPDVAKVELVGLQ-DQKIWI 189
+ GDT NI +V T D + +Y A +Q L RV V ++ G Q +IW+
Sbjct 131 KTGDT--NILTIAFVSTDGSMDKQDIADYVASNIQDPLSRVNGVGDIDAYGSQYSMRIWL 188
Query 190 ELSNTKMAQLGVPVTAIQQALQQQNNMVSAGFFE-TPSDRIQ-----VRLTGHLNRVEDL 243
+ + K+ + + A++ QN ++ G TPS Q + L E
Sbjct 189 DPA--KLNSFQMTAKDVTDAIESQNAQIAVGQLGGTPSVDKQALNATINAQSLLQTPEQF 246
Query 244 KHLPLLVGD--KTIQLGEVAEIYRGFSDPAQPRMRFMGQNGIGIAVSMRKGGDIIALGKH 301
+ + L V ++LG+VA + G ++ RF G+ G+ V + G + +A +
Sbjct 247 RDITLRVNQDGSEVRLGDVATVEMG-AEKYDYLSRFNGKPASGLGVKLASGANEMATAEL 305
Query 302 LETTFSDLQHTLPLGMKLEKVSDQPVAVQRSIHEFIKVLAEAVIIVLLVSFFSL-GFRTG 360
+ +L P G++ + + V+ SI + +K L EA+ +V LV + L FR
Sbjct 306 VLNRLDELAQYFPHGLEYKVAYETTSFVKASIEDVVKTLLEAIALVFLVMYLFLQNFRAT 365
Query 361 LVVAFSIPLVLAMTFAGMHIFDVGLHKISLGALILALGLLVDDAIIAVE-MMAIKMEQGY 419
L+ ++P+VL TF+ ++ F ++ +++ A++LA+GLLVDDAI+ VE + I E+G
Sbjct 366 LIPTIAVPVVLMGTFSVLYAFGYSVNTLTMFAMVLAIGLLVDDAIVVVENVERIMSEEGL 425
Query 420 SRLKAAGFAWKSTAFPMLTGTLITAAGFLPIATANSSTGEYTRSIFQVVTIALIVSWVAA 479
+ +A + ++ ++ +A F+P+A +TG R + A+++S + A
Sbjct 426 TPREATRKSMGQIQGALVGIAMVLSAVFVPMAFFGGTTGAIYRQFSITIVAAMVLSVLVA 485
Query 480 VLFVPYLGEKLLPDFNQMQQRVPWYQRIWAKLRKQPVPQLASYQEHHDPYQTRFYQTFRN 539
++ P L LL + EHH Q F+ F
Sbjct 486 MILTPALCATLLKPLKK--------------------------GEHHG--QKGFFAWFNQ 517
Query 540 MVEA-CVRYRKTV----------IVTTVLLFAGSLLLFKFVPQQFFPPSNRAEILVDIKL 588
M RY K V IV VLL G + LF +P F P +R ++L
Sbjct 518 MFNRNAERYEKGVAKILHRSLRWIVIYVLLLGGMVFLFLRLPTSFLPLEDRGMFTTSVQL 577
Query 589 EEGASLTATEQAVKKVE--HFLSQQKGIDNYVAYVGTGS-------PRFYLPLD--QQLP 637
G++ T + V+++E +F ++ I + A VG+G R ++ L +
Sbjct 578 PSGSTQQQTLKVVEQIEKYYFTHEKDNIMSVFATVGSGPGGNGQNVARMFIRLKDWSERD 637
Query 638 QASFAQFVVLASSLEDRNEIRHSLDQQIKLLLPQARTRVSLLENGPPVGYPLQYR-VSGE 696
+ F ++ + + N+I+ + ++ + +S L G G+ ++ + +G
Sbjct 638 SKTGTSFAIIERATKAFNQIKEA------RVIASSPPAISGL--GSSAGFDMELQDHAGA 689
Query 697 DQNLVREWAQKVAKVIAENPNATNVHLDWGEPSKLIMLNIDQDRARQLGVSNTDLANFLN 756
+ + ++ + AENP T V + + S + ++IDQ +A+ LGV+ D+ + L
Sbjct 690 GHDALMAARNQLLALAAENPELTRVRHNGLDDSPQLQIDIDQRKAQALGVAIDDINDTLQ 749
Query 757 SSITGTVIDQYREKRELIEIRLRGDQAERVDVASLASLAIPTSHGGTVPLAQIARIEYRF 816
++ + ++ + ++ + ++ ++ R+ + + GG VP + A +
Sbjct 750 TAWGSSYVNDFMDRGRVKKVYVQAAAPYRMLPDDINLWYVRNKDGGMVPFSAFATSRWET 809
Query 817 EDGIIWHRDRLPTITVRADMRSQLQPATVVDQMKLQMQELRRQLPNGYLIDVGGTVEESA 876
+ + + + + + T +D M+ L +QLPNG+ ++ +
Sbjct 810 GSPRLERYNGYSAVEIVGEAAPGVSTGTAMD----IMESLVKQLPNGFGLEWTAMSYQER 865
Query 877 KGQESVNAGMPLFLAVVMTLLMVKLRSLSRAFIVFLTAPLGLIGVTLFLLLFDKPFGFVA 936
A + L VV L S S F V L PLG+IG L +
Sbjct 866 LSGAQAPALYAISLLVVFLCLAALYESWSVPFSVMLVVPLGVIGALLATWMRGLENDVYF 925
Query 937 MLGTIALSGMIMRNALILIDQIEQDVAAGHEVWTAIIDATVRRFRPILLTALAAVLAMIP 996
+G + + G+ +NA+++++ + GH+++ A + A +R RPIL+T+LA + ++P
Sbjct 926 QVGLLTVIGLSAKNAILIVEFANEMNQKGHDLFEATLHACRQRLRPILMTSLAFIFGVLP 985
Query 997 LSRSIFFG-----PMAVAIMGGLIVATFLTLFFLPALY 1029
++ S G + +MGG+I AT L ++F+P +
Sbjct 986 MATSTGAGSGGQHAVGTGVMGGMISATILAIYFVPLFF 1023
>Q8FWV9 Efflux pump membrane transporter BepG [Brucella suis biovar
1 (strain 1330)]
Length=1074
Score = 247 bits (630), Expect = 1e-70
Identities = 241/1066 (23%), Positives = 464/1066 (44%), Gaps = 66/1066 (6%)
Query 5 LSEWALKNKGLILYLMLLLAIVGIFSYSKLSQSEDPPFTFKVMVIKTYWPGATAKEVSTL 64
LS + L + + +++ + G+ + +++ ++ P + + +PGA+A+ V
Sbjct 2 LSSVFINRPRLAIVIAIVITLAGLIAVTRIPVAQFPDIVPPQVSVTATYPGASAETVEAA 61
Query 65 VTDRIEKELMTTGQYDHIMAYSRPGESMVTFFAKDSLKSEQIPDV-WYNVRKKVNDIKQE 123
+ IE ++ G D I S G + T+ + K P++ NV+ +V +
Sbjct 62 IAQPIEAQV--NGVDDMIYMSSTSGNNG-TYTLTVTFKVGSDPNLNTVNVQNRVRLAEAN 118
Query 124 LPVGVQ--GPFFNDEFGDTFGNIYVLTGEG-FDYAVLKEYADRLQLE-LQRVPDVAKVEL 179
LP V G + I +L+ + +D L Y ++ L RVP V + +
Sbjct 119 LPQEVTRLGVTVKKQSSSFLQIITLLSPDSRYDELFLNNYGVINVVDRLARVPGVGQAQS 178
Query 180 VGLQDQKIWIELSNTKMAQLGVPVTAIQQALQQQNNMVSAGFFETP--SDRIQVRLT--- 234
G + + I + + L + I A+ QN + G P +D+ Q++LT
Sbjct 179 FGTFNYSMRIWFNTDALTSLNLTPNDIVNAISSQNVQAAVGRLGAPPMTDQQQIQLTLTT 238
Query 235 -GHLNRVEDLKHLPLLVGD--KTIQLGEVAEIYRGFSDPAQPRMRFMGQNGIGIAVSMRK 291
G L + +++ + +++L +VA + + R G+ IAV
Sbjct 239 QGRLTDAKQFENIIIRANPDGSSVRLKDVARVELA-AQSYDTIGRLNGKPASVIAVYQAP 297
Query 292 GGDIIALGKHLETTFSDLQHTLPLGMKLEKVSDQPVAVQRSIHEFIKVLAEAVIIVLLVS 351
G + +A + + L+ + P G+ + D V V +IHE IK L EA ++V++V
Sbjct 298 GSNAVAAAEGVRNVMEQLKQSFPAGLDYKITYDTTVFVSSTIHEVIKTLLEAFVLVVVVV 357
Query 352 FFSLG-FRTGLVVAFSIPLVLAMTFAGMHIFDVGLHKISLGALILALGLLVDDAIIAVEM 410
F LG FR L+ ++P+ L TFA + + + ISL A+ILA+G++VDDAI+ VE
Sbjct 358 FIFLGNFRATLIPTLAVPVSLIGTFAVLLVLGFSANTISLFAMILAIGIVVDDAIVVVEN 417
Query 411 MA-IKMEQGYSRLKAAGFAWKSTAFPMLTGTLITAAGFLPIATANSSTGEYTRSIFQVVT 469
+ + E G +AA A + P++ TL+ + F+P+A TG V+
Sbjct 418 VERVMAETGLPPKEAAKQAMQEITAPIIAITLVLLSVFVPVAFIPGITGALYAQFALTVS 477
Query 470 IALIVSWVAAVLFVPYLGEKLLPDFNQMQQRVPWYQRIWAKLRKQPVPQLASYQEHHDPY 529
+A+++S + A+ P L L ++ + Y R KL + ++ D Y
Sbjct 478 VAMLISAINALTLSPALCGVFLKPHQGRKKSL--YGRTMDKLS-------SGIEKISDGY 528
Query 530 QTRFYQTFRNMVEACVRYRKTVIVTTVLLFAGSLLLFKFVPQQFFPPSNRAEILVDIKLE 589
++V VR IV L AG+ L VP F P ++ V + L
Sbjct 529 A--------HIVRRLVRMAFLSIVLVAGLGAGAYFLNTIVPTGFLPEEDQGLFFVQVNLP 580
Query 590 EGASLTATEQAVKKVEHFLSQQKGIDNYVAYVGTGSPRFYLPLDQQLPQASFAQFVVLAS 649
AS + T V ++E +++ G+ + + G L ++ +V
Sbjct 581 PAASQSRTAAVVSEIEADITKMAGVADVTSVTG-------FSFIDGLAVSNAGLMIVTLK 633
Query 650 SLEDR---NEIRHSLDQQIKLLLPQARTRVSLLENGPPV-------GYPLQYR-VSGEDQ 698
LE+R N + ++ + V++ N PP+ G+ Q G+
Sbjct 634 PLEERLKDNITVFDVIAEVNRRTAAIPSAVAITMNLPPILGLGSSGGFQYQLEDQEGQSP 693
Query 699 NLVREWAQKVAKVIAENPNATNVHLDWGEPSKLIMLNIDQDRARQLGVSNTDLANFLNSS 758
+ AQ + +NP + V + + + LNID+ +A LGVS ++ L S+
Sbjct 694 QQLASVAQGLVMAANQNPKLSRVFTTFATDTPQLNLNIDRQKALSLGVSPNNIIQALQST 753
Query 759 ITGTVIDQYREKRELIEIRLRGDQAERVDVASLASLAIPTSHGGTVPLAQIARIEYRFED 818
+ G ++ + ++ ++G+Q +R V + + + +SHG VPL + +E R
Sbjct 754 LGGYFVNNFNTLGRTWQVIIQGEQQDRKTVEDIYRINVRSSHGDMVPLRSLVSVEERLGP 813
Query 819 GIIWHRDRLPTITVRADMRSQLQPATVVDQMKLQMQELRRQLPNGYLIDVGGTV--EESA 876
I + + +++ + + + M Q + LP+GY + GT E A
Sbjct 814 LYITRYNNYRSASIQGNAAPGVSSGEALAAM---AQVSKTTLPSGYGYEWTGTALQELQA 870
Query 877 KGQESVNAGMPLFLAVVMTLLMVKLRSLSRAFIVFLTAPLGLIGVTLFLLLFDKPFGFVA 936
GQ S+ + + A + + + + ++ ++ +TA GL G L L + A
Sbjct 871 AGQTSMILALAVLFAYLFLVALYESWTIPVGVLLSVTA--GLAGAMLALWITGLSNDIYA 928
Query 937 MLGTIALSGMIMRNALILIDQIEQDVAAGHEVWTAIIDATVRRFRPILLTALAAVLAMIP 996
+G + L + +N +++++ ++ G + A I +RFRP+++T+ A +L ++P
Sbjct 929 QIGIVVLIALASKNGILIVEFAKERREEGVPLEQAAIIGARQRFRPVMMTSFAFILGLVP 988
Query 997 LSRSIFFG-----PMAVAIMGGLIVATFLTLFFLPALYAAWFKVKK 1037
L ++ + ++ GG+I A+ + +F +P LY +V++
Sbjct 989 LVIAVGAAAASRRAVGTSVFGGMIAASAVGIFLIPMLYVVLERVRE 1034
>Q48815 Protein HelA [Legionella pneumophila]
Length=1052
Score = 246 bits (628), Expect = 2e-70
Identities = 260/1076 (24%), Positives = 476/1076 (44%), Gaps = 106/1076 (10%)
Query 8 WALKNKGLILYLMLLLAIVGIFSYSKLSQSEDPPFTFKVMVIKTYWPGATAKEVSTLVTD 67
++LK++ +L L++AI+G++++ +L P T + I T G + EV +T
Sbjct 8 FSLKHRWFVLLFTLVIAILGVYNFQRLPIDAVPDITNVQVQINTQASGYSPFEVEQRITF 67
Query 68 RIEKELMTTGQYDHIMAYSRPGESMVTFFAKDSLKSEQIPDVWYNVRKKVNDIKQELPVG 127
IE + D+ + SR G S VT KD + + +++ ++K +LP G
Sbjct 68 PIELAMSGLPSLDYTRSLSRYGLSQVTVVFKDGTNIYFARQL---INERLQEVKDKLPPG 124
Query 128 VQGPFFNDEFGDTFGNIYVLTGEGFDYAV-------LKEYADRLQL----------ELQR 170
V+ T G I GE F Y V + ++ + +L +L+
Sbjct 125 VE---------TTLGPISTGLGEIFMYTVTNKPNVPISQHYNPTELRTIQDWIIKPQLRN 175
Query 171 VPDVAKVELVGLQDQKIWIELSNTKMAQLGVPVTAIQQALQQQNNMVSAGFFETPSDRIQ 230
V VA+V +G +++ I +K+ + + + + +AL++ N V AG+ ET ++
Sbjct 176 VEGVAEVNTIGGYEKQFHITPDPSKLVRYRLSLNDVVEALERNNANVGAGYIETNGEQNL 235
Query 231 VRLTGHLNRVEDLKHLPLLVGDKT-IQLGEVAEIYRGFSDPAQPRMRFMGQNGIGIAVSM 289
+R+ G + + D++++ + + T +++ +VAE+ G + +G V +
Sbjct 236 IRVPGQVQNMADIENIVIASFEGTPVRIRDVAEVALGKELRTGAATENSKEVVLG-TVFI 294
Query 290 RKGGDIIALGKHLETTFSDLQHTLPLGMKLEKVSDQPVAVQRSIHEFIKVLAEAVIIVLL 349
G + + + + D+ TLP G++ V ++ V +I+ L E ++V +
Sbjct 295 LMGENSRTVSERVAAKMKDINKTLPEGVEAITVYNRTTLVNATINTVKNNLLEGALLVCV 354
Query 350 VSFFSLG-FRTGLVVAFSIPLVLAMTFAGMHIFDVGLHKISLGALILALGLLVDDAIIAV 408
+ F LG R L+ A IPL + +T GM + + +SLGAL GL+VD A+I V
Sbjct 355 ILFLFLGNIRAALITAMVIPLSMLLTITGMVENQISANLMSLGAL--DFGLIVDGAVIIV 412
Query 409 EMMAIKM-EQGYS---------RLKAAGFAWKSTAFPMLTGTLITAAGFLPIATANSSTG 458
E + EQ ++ RLK +A P + G I +LPI T G
Sbjct 413 ENCIKHLAEQQHALHRVLNLEERLKVISYATTEVIRPSIFGVFIITVVYLPILTLTGVEG 472
Query 459 EYTRSIFQVVTIALIVSWVAAVLFVPYLGEKLLPDFNQMQQRVPWYQRIWAKLRKQPVPQ 518
+ + Q V IAL+ S + A+ FVP L +Q++ W
Sbjct 473 KMFLPMAQTVIIALLASMLFALTFVPAAVAIFLR--GHLQEKENW--------------- 515
Query 519 LASYQEHHDPYQTRFYQTFRNMVEACVRYRKTVIVTTVLLFAGSLLLFKFVPQQFFPPSN 578
L Y + ++ C R+ VI V L SL + + +F P +
Sbjct 516 LVHY----------LSLGYAKVLRRCFHARRVVISAAVALVVVSLGIAFHLGGEFIPSLD 565
Query 579 RAEILVDIKLEEGASLTATEQAVKKVEHFLSQQKGIDNYVAYVGTGSPRFYLPLDQQLPQ 638
+I + G SLT VE + Q + N A +GT + D P
Sbjct 566 EGDIAMHAMRIPGTSLTQAITMQDLVEKRIRQFSEVKNVFAKLGTAE----VATDPMPPN 621
Query 639 ASFAQFVVLASSLEDRN--EIRHSLDQQIKLLLPQ-----------ARTRVSLLENGPPV 685
+ F++L S + N + + L Q+I+ + Q + R + L +G V
Sbjct 622 VA-DTFIILKSRKKWTNPKKTKPGLVQEIESAVQQIPGNNYEFTQPIQMRFNELISG--V 678
Query 686 GYPLQYRVSGEDQNLVREWAQKVAKVIAENPNATNVHLDWGEPSKLIMLNIDQDRARQLG 745
+ +V G+D + + + A+ ++ + + P A +V ++ L+ + I++D + G
Sbjct 679 RSDVAVKVFGDDMDTLLKTAEAISAQLKQVPGAADVKVEQVSGLPLLTVEINRDVLARYG 738
Query 746 VSNTDLANFLNSSITGTVIDQYREKRELIEIRLRGDQAERVDVASLASLAI--PTSHGGT 803
+ + + + G + E + +I +R ++ R D L + I P S G
Sbjct 739 LQIGTVQEAVVIATGGKKGGELFEGDKRFDIVVRLPESLRSDPNVLRQIFIPLPLSKDGE 798
Query 804 ---VPLAQIARIEYRFEDGIIWHRDRLPTITVRADMRSQLQPATVVDQMKLQMQELRRQL 860
+PL+++A + I + + V A++R++ ++ V + K ++ + + +L
Sbjct 799 QHFIPLSEVASLIRSESPNQISRENGKRRVVVTANVRNR-DLSSFVSEAKKRI-DGQVKL 856
Query 861 PNGYLIDVGGTVEESAKGQESVNAGMPLFLAVVMTLLMVKLRSLSRAFIVFLTAPLGLIG 920
P+GY I GG E+ + + +P+ L + LL + + A +VF PL L G
Sbjct 857 PSGYWITWGGQFEQLQSAYQRLQIVVPITLLGIFLLLFISFGKVRDALLVFTGIPLALTG 916
Query 921 VTLFLLLFDKPFGFVAMLGTIALSGMIMRNALILIDQIEQDVAAGHEVW--TAIIDATVR 978
L L P A +G IALSG+ + N L++I I + + +V+ A++ ++
Sbjct 917 GVFALWLRGIPLSISAGVGFIALSGVAVLNGLVMITFINK-LREQKKVYLKDAVLQGSLA 975
Query 979 RFRPILLTALAAVLAMIPLSRSIFFG-----PMAVAIMGGLIVATFLTLFFLPALY 1029
R RP+L+TAL A L +P++ + G P+A ++GG+I +TFLTL LP LY
Sbjct 976 RLRPVLMTALVASLGFVPMALATGTGSEVQRPLATVVIGGIISSTFLTLLVLPGLY 1031
Score = 34.3 bits (77), Expect = 8e-04
Identities = 38/209 (18%), Positives = 89/209 (43%), Gaps = 22/209 (11%)
Query 844 TVVDQMKLQMQELRRQLPNGYLIDVGGTVEESAKGQESVNAGMPLFLA---VVMTLLMVK 900
TV +++ +M+++ + LP G ++ + ++N L +V +L +
Sbjct 302 TVSERVAAKMKDINKTLPEG--VEAITVYNRTTLVNATINTVKNNLLEGALLVCVILFLF 359
Query 901 LRSLSRAFIVFLTAPLGLIGVTLFLLLFDKPFGFVAMLGTIALSGMIMRNALILIDQIEQ 960
L ++ A I + PL ++ +T+ ++ ++ + LG + G+I+ A+I+++ +
Sbjct 360 LGNIRAALITAMVIPLSML-LTITGMVENQISANLMSLGALDF-GLIVDGAVIIVENCIK 417
Query 961 DVAAGHEVWTAIID----------ATVRRFRPILLTALAAVLAMIPLS-----RSIFFGP 1005
+A +++ AT RP + + +P+ F P
Sbjct 418 HLAEQQHALHRVLNLEERLKVISYATTEVIRPSIFGVFIITVVYLPILTLTGVEGKMFLP 477
Query 1006 MAVAIMGGLIVATFLTLFFLPALYAAWFK 1034
MA ++ L+ + L F+PA A + +
Sbjct 478 MAQTVIIALLASMLFALTFVPAAVAIFLR 506
>P24181 Multidrug export protein AcrF [Escherichia coli (strain
K12)]
Length=1034
Score = 239 bits (610), Expect = 4e-68
Identities = 251/1056 (24%), Positives = 467/1056 (44%), Gaps = 90/1056 (9%)
Query 19 LMLLLAIVGIFSYSKLSQSEDPPFTFKVMVIKTYWPGATAKEVSTLVTDRIEKELMTTGQ 78
L ++L + G + +L ++ P + + +PGA A+ V VT IE+ +
Sbjct 15 LAIILMMAGALAILQLPVAQYPTIAPPAVSVSANYPGADAQTVQDTVTQVIEQNM---NG 71
Query 79 YDHIMAYSRPGESMVTFFAKDSLKSEQIPDV-WYNVRKKVNDIKQELPVGVQGPFFNDEF 137
D++M S +S + + +S PD+ V+ K+ LP VQ + E
Sbjct 72 IDNLMYMSSTSDSAGSVTITLTFQSGTDPDIAQVQVQNKLQLATPLLPQEVQQQGISVEK 131
Query 138 GDTFGNI---YVLTGEGFDYAVLKEY-ADRLQLELQRVPDVAKVELVGLQ-DQKIWIELS 192
+ + +V G + +Y A ++ L R+ V V+L G Q +IW++
Sbjct 132 SSSSYLMVAGFVSDNPGTTQDDISDYVASNVKDTLSRLNGVGDVQLFGAQYAMRIWLDAD 191
Query 193 NTKMAQLGVPVTAIQQALQQQNNMVSAGFF----ETPSDRIQVRLTGH--LNRVEDLKHL 246
+L PV I Q L+ QN+ ++AG P ++ + E+ +
Sbjct 192 LLNKYKL-TPVDVINQ-LKVQNDQIAAGQLGGTPALPGQQLNASIIAQTRFKNPEEFGKV 249
Query 247 PLLVGD--KTIQLGEVAEIYRGFSDPAQPRMRFMGQNGIGIAVSMRKGGDIIALGKHLET 304
L V ++L +VA + G + R G+ G+ + + G + + K ++
Sbjct 250 TLRVNSDGSVVRLKDVARVELG-GENYNVIARINGKPAAGLGIKLATGANALDTAKAIKA 308
Query 305 TFSDLQHTLPLGMKLEKVSDQPVAVQRSIHEFIKVLAEAVIIVLLVSFFSL-GFRTGLVV 363
++LQ P GMK+ D VQ SIHE +K L EA+++V LV + L R L+
Sbjct 309 KLAELQPFFPQGMKVLYPYDTTPFVQLSIHEVVKTLFEAIMLVFLVMYLFLQNMRATLIP 368
Query 364 AFSIPLVLAMTFAGMHIFDVGLHKISLGALILALGLLVDDAIIAVE-MMAIKMEQGYSRL 422
++P+VL TFA + F ++ +++ ++LA+GLLVDDAI+ VE + + ME
Sbjct 369 TIAVPVVLLGTFAILAAFGYSINTLTMFGMVLAIGLLVDDAIVVVENVERVMMEDKLPPK 428
Query 423 KAAGFAWKSTAFPMLTGTLITAAGFLPIATANSSTGEYTRSIFQVVTIALIVSWVAAVLF 482
+A + ++ ++ +A F+P+A STG R + A+ +S + A++
Sbjct 429 EATEKSMSQIQGALVGIAMVLSAVFIPMAFFGGSTGAIYRQFSITIVSAMALSVLVALIL 488
Query 483 VPYLGEKLLPDFNQMQQRVPWYQRIWAKLRKQPVPQLASYQEHHDPYQTRFYQTFRNMVE 542
P L LL P A + E+ + F TF + V
Sbjct 489 TPALCATLLK------------------------PVSAEHHENKGGFFGWFNTTFDHSVN 524
Query 543 ACVRYRKTVIVTT-------VLLFAGSLLLFKFVPQQFFPPSNRAEILVDIKLEEGASLT 595
++ +T L+ AG ++LF +P F P ++ L I+L GA+
Sbjct 525 HYTNSVGKILGSTGRYLLIYALIVAGMVVLFLRLPSSFLPEEDQGVFLTMIQLPAGATQE 584
Query 596 ATEQAVKKV-EHFLSQQKGIDNYVAYVGTGSPRFYLPLDQQLPQASFAQFVVLASSLEDR 654
T++ + +V +++L +K V V S Q A A FV L E+R
Sbjct 585 RTQKVLDQVTDYYLKNEKANVESVFTVNGFS------FSGQAQNAGMA-FVSL-KPWEER 636
Query 655 NEIRHSLDQQI---KLLLPQAR-------TRVSLLENGPPVGYPLQ-YRVSGEDQNLVRE 703
N +S + I K+ L + R +++E G G+ + +G + + +
Sbjct 637 NGDENSAEAVIHRAKMELGKIRDGFVIPFNMPAIVELGTATGFDFELIDQAGLGHDALTQ 696
Query 704 WAQKVAKVIAENP-NATNVHLDWGEPSKLIMLNIDQDRARQLGVSNTDLANFLNSSITGT 762
++ + A++P + +V + E + L +DQ++A+ LGVS +D+ +++++ GT
Sbjct 697 ARNQLLGMAAQHPASLVSVRPNGLEDTAQFKLEVDQEKAQALGVSLSDINQTISTALGGT 756
Query 763 VIDQYREKRELIEIRLRGDQAERVDVASLASLAIPTSHGGTVPLAQIARIEYRFEDGIIW 822
++ + ++ + ++ ++ D R+ + L + +++G VP + + + +
Sbjct 757 YVNDFIDRGRVKKLYVQADAKFRMLPEDVDKLYVRSANGEMVPFSAFTTSHWVYGSPRLE 816
Query 823 HRDRLPTITVRADMRSQLQPATVVDQMKLQMQELRRQLPNGYLIDVGGTVEESAKGQESV 882
+ LP++ +++ + P T M+ L +LP G D G +
Sbjct 817 RYNGLPSM----EIQGEAAPGTSSGDAMALMENLASKLPAGIGYDWTGMSYQERLSGNQA 872
Query 883 NAGMPLFLAVVMTLLMVKLRSLSRAFIVFLTAPLGLIGVTLFLLLFDKPFGFVAMLGTIA 942
A + + VV L S S V L PLG++GV L LF++ M+G +
Sbjct 873 PALVAISFVVVFLCLAALYESWSIPVSVMLVVPLGIVGVLLAATLFNQKNDVYFMVGLLT 932
Query 943 LSGMIMRNALILI----DQIEQDVAAGHEVWTAIIDATVRRFRPILLTALAAVLAMIPLS 998
G+ +NA++++ D +E++ G V A + A R RPIL+T+LA +L ++PL+
Sbjct 933 TIGLSAKNAILIVEFAKDLMEKE---GKGVVEATLMAVRMRLRPILMTSLAFILGVLPLA 989
Query 999 RSIFFG-----PMAVAIMGGLIVATFLTLFFLPALY 1029
S G + + +MGG++ AT L +FF+P +
Sbjct 990 ISNGAGSGAQNAVGIGVMGGMVSATLLAIFFVPVFF 1025
>P76399 Multidrug resistance protein MdtC [Escherichia coli (strain
K12)]
Length=1025
Score = 236 bits (602), Expect = 4e-67
Identities = 225/1039 (22%), Positives = 447/1039 (43%), Gaps = 74/1039 (7%)
Query 17 LYLMLLLAIVGIFSYSKLSQSEDPPFTFKVMVIKTYWPGATAKEVSTLVTDRIEKELMTT 76
+ L + + + GI + L + P F V+++ PGA+ + +++ V +E+ L
Sbjct 15 ILLSVAITLCGILGFRMLPVAPLPQVDFPVIIVSASLPGASPETMASSVATPLERSLGRI 74
Query 77 GQYDHIMAYSRPGESMVTF---FAKDSLKSEQIPDVWYNVRKKVNDIKQELPVGVQG--P 131
+ + S G + + F +D I +V+ +N + LP G+
Sbjct 75 AGVSEMTSSSSLGSTRIILQFDFDRD------INGAARDVQAAINAAQSLLPSGMPSRPT 128
Query 132 FFNDEFGDTFGNIYVLTGEGFDYAVLKEYAD-RLQLELQRVPDVAKVELVGLQDQKIWIE 190
+ D I LT + + L ++A +L + ++ V V++ G + +
Sbjct 129 YRKANPSDAPIMILTLTSDTYSQGELYDFASTQLAPTISQIDGVGDVDVGGSSLPAVRVG 188
Query 191 LSNTKMAQLGVPVTAIQQALQQQNNMVSAGFFETPSDRIQVRLTGHLNRVEDLKHLPLLV 250
L+ + GV + ++ A+ N G E + R Q++ L + + PL++
Sbjct 189 LNPQALFNQGVSLDDVRTAVSNANVRKPQGALEDGTHRWQIQTNDELKTAAEYQ--PLII 246
Query 251 ---GDKTIQLGEVAEIYRGFSDPAQPRMRFMGQNGIGIAVSMRKGGDIIALGKHLETTFS 307
++LG+VA + D M + I + + +II +
Sbjct 247 HYNNGGAVRLGDVATVTDSVQDVRNAGMT-NAKPAILLMIRKLPEANIIQTVDSIRAKLP 305
Query 308 DLQHTLPLGMKLEKVSDQPVAVQRSIHEFIKVLAEAVIIVLLVSFFSL-GFRTGLVVAFS 366
+LQ T+P + L+ D+ ++ S+ E + L +V +V+LV F L R ++ A S
Sbjct 306 ELQETIPAAIDLQIAQDRSPTIRASLEEVEQTLIISVALVILVVFLFLRSGRATIIPAVS 365
Query 367 IPLVLAMTFAGMHIFDVGLHKISLGALILALGLLVDDAIIAVEMMAIKMEQGYSRLKAAG 426
+P+ L TFA M++ L+ +SL AL +A G +VDDAI+ +E +A +E G L+AA
Sbjct 366 VPVSLIGTFAAMYLCGFSLNNLSLMALTIATGFVVDDAIVVLENIARHLEAGMKPLQAAL 425
Query 427 FAWKSTAFPMLTGTLITAAGFLPIATANSSTGEYTRSIFQVVTIALIVSWVAAVLFVPYL 486
+ F +L+ +L A FLP+ G R +++A+ +S + ++ P +
Sbjct 426 QGTREVGFTVLSMSLSLVAVFLPLLLMGGLPGRLLREFAVTLSVAIGISLLVSLTLTPMM 485
Query 487 -GEKLLPDFNQMQQRVPWYQRIWAKLRKQPVPQLASYQEHHDPYQTRFYQTFRNMVEACV 545
G L + Q+R+ + R+ L+ Q + ++ +
Sbjct 486 CGWMLKASKPREQKRLRGFGRMLVALQ----------------------QGYGKSLKWVL 523
Query 546 RYRKTVIVTTVLLFAGSLLLFKFVPQQFFPPSNRAEILVDIKLEEGASLTATEQAVKKVE 605
+ + V V + A ++ L+ +P+ FFP + ++ I+ ++ S A ++
Sbjct 524 NHTRLVGVVLLGTIALNIWLYISIPKTFFPEQDTGVLMGGIQADQSISFQAMRGKLQDFM 583
Query 606 HFLSQQKGIDNYVAYVG---TGSPRFYLPLDQQLPQASFAQFVVLASSLEDRNEIRHSLD 662
+ +DN + G S ++ L + ++ AQ ++ DR ++ + +
Sbjct 584 KIIRDDPAVDNVTGFTGGSRVNSGMMFITLKPRDERSETAQQII------DRLRVKLAKE 637
Query 663 QQIKLLLPQARTRVSLLENGPPVGYPLQYRVSGEDQNLVREWAQKVAKVIAENPNATNVH 722
L L + + G QY + +D +REW K+ K +A P +V+
Sbjct 638 PGANLFLMAVQ---DIRVGGRQSNASYQYTLLSDDLAALREWEPKIRKKLATLPELADVN 694
Query 723 LDWGEPSKLIMLNIDQDRARQLGVSNTDLANFLNSSITGTVIDQYREKRELIEIRLRGDQ 782
D + + L D+D +LG+ + LN++ I + ++ + D
Sbjct 695 SDQQDNGAEMNLVYDRDTMARLGIDVQAANSLLNNAFGQRQISTIYQPMNQYKVVMEVDP 754
Query 783 AERVDVASLASLAIPTSHGGTVPLAQIARIEYRFEDGIIWHRDRLPTITVRADM---RSQ 839
D+++L + + + G +PL+ A+ + + H+ T+ ++ +S
Sbjct 755 RYTQDISALEKMFVINNEGKAIPLSYFAKWQPANAPLSVNHQGLSAASTISFNLPTGKSL 814
Query 840 LQPATVVDQMKLQMQELRRQLPNGYLIDVGGTVEESAKGQESVNAGMPLFLAVVMT---L 896
+ +D+ Q+ +P+ GT + QE++N+ + L +A + T +
Sbjct 815 SDASAAIDRAMTQL-----GVPSTVRGSFAGTAQVF---QETMNSQVILIIAAIATVYIV 866
Query 897 LMVKLRSLSRAFIVFLTAPLGLIGVTLFLLLFDKPFGFVAMLGTIALSGMIMRNALILID 956
L + S + T P +G L L LF+ PF +A++G + L G++ +NA++++D
Sbjct 867 LGILYESYVHPLTILSTLPSAGVGALLALELFNAPFSLIALIGIMLLIGIVKKNAIMMVD 926
Query 957 -QIEQDVAAGHEVWTAIIDATVRRFRPILLTALAAVLAMIPLSRSIFFG-----PMAVAI 1010
+E AI A + RFRPI++T LAA+ +PL S G P+ + I
Sbjct 927 FALEAQRHGNLTPQEAIFQACLLRFRPIMMTTLAALFGALPLVLSGGDGSELRQPLGITI 986
Query 1011 MGGLIVATFLTLFFLPALY 1029
+GGL+++ LTL+ P +Y
Sbjct 987 VGGLVMSQLLTLYTTPVVY 1005
>P52002 Multidrug resistance protein MexB [Pseudomonas aeruginosa
(strain ATCC 15692 / DSM 22644 / CIP 104116 / JCM 14847
/ LMG 12228 / 1C / PRS 101 / PAO1)]
Length=1046
Score = 234 bits (597), Expect = 2e-66
Identities = 237/1052 (23%), Positives = 440/1052 (42%), Gaps = 79/1052 (8%)
Query 19 LMLLLAIVGIFSYSKLSQSEDPPFTFKVMVIKTYWPGATAKEVSTLVTDRIEKELMTTGQ 78
+ L++ + G S L ++ P + ++ +PGA+A+ V V IE+++
Sbjct 15 IALVIMLAGGLSILSLPVNQYPAIAPPAIAVQVSYPGASAETVQDTVVQVIEQQMNGIDN 74
Query 79 YDHIMAYSRPGESMVTFFAKDSLKSEQIPDVWYNVRKKVNDIKQELPVGVQGPFFNDEFG 138
+I + S SM + I V V+ K+ LP VQ
Sbjct 75 LRYISSESNSDGSMTITVTFEQGTDPDIAQV--QVQNKLQLATPLLPQEVQRQGIR--VT 130
Query 139 DTFGNIYVLTGE-GFDYAVLKE-----YADRLQLELQRVPDVAKVELVGLQ-DQKIWIEL 191
N ++ G D ++ KE +Q L R V ++ G Q +IW++
Sbjct 131 KAVKNFLMVVGVVSTDGSMTKEDLSNYIVSNIQDPLSRTKGVGDFQVFGSQYSMRIWLDP 190
Query 192 SNTKMAQLGVPVTAIQQALQQQNNMVSAGFF----ETPSDRIQVRLTG--HLNRVEDLKH 245
+ QL + A+Q QN +S+G ++ + G L E ++
Sbjct 191 AKLNSYQL--TPGDVSSAIQAQNVQISSGQLGGLPAVKGQQLNATIIGKTRLQTAEQFEN 248
Query 246 LPLLVGD--KTIQLGEVAEIYRGFSDPAQPRMRFMGQNGIGIAVSMRKGGDIIALGKHLE 303
+ L V ++L +VA++ G D + +F G GIA+ + G + + K +
Sbjct 249 ILLKVNPDGSQVRLKDVADVGLGGQDYSI-NAQFNGSPASGIAIKLATGANALDTAKAIR 307
Query 304 TTFSDLQHTLPLGMKLEKVSDQPVAVQRSIHEFIKVLAEAVIIVLLVSF-FSLGFRTGLV 362
T ++L+ +P GMK+ D V SIHE +K L EA+++V LV + F FR L+
Sbjct 308 QTIANLEPFMPQGMKVVYPYDTTPVVSASIHEVVKTLGEAILLVFLVMYLFLQNFRATLI 367
Query 363 VAFSIPLVLAMTFAGMHIFDVGLHKISLGALILALGLLVDDAIIAVE-MMAIKMEQGYSR 421
++P+VL TF + F ++ +++ ++LA+GLLVDDAI+ VE + + E+G S
Sbjct 368 PTIAVPVVLLGTFGVLAAFGFSINTLTMFGMVLAIGLLVDDAIVVVENVERVMAEEGLSP 427
Query 422 LKAAGFAWKSTAFPMLTGTLITAAGFLPIATANSSTGEYTRSIFQVVTIALIVSWVAAVL 481
+AA + ++ ++ +A FLP+A STG R + A+ +S + A++
Sbjct 428 REAARKSMGQIQGALVGIAMVLSAVFLPMAFFGGSTGVIYRQFSITIVSAMALSVIVALI 487
Query 482 FVPYLGEKLLPDFNQMQQR------VPWYQRIWAKLRKQPVPQLASYQEHHDPYQTRFYQ 535
P L +L + W+ R++ +AS +H PY
Sbjct 488 LTPALCATMLKPIEKGDHGEHKGGFFGWFNRMFLSTTHGYERGVASILKHRAPY------ 541
Query 536 TFRNMVEACVRYRKTVIVTTVLLFAGSLLLFKFVPQQFFPPSNRAEILVDIKLEEGASLT 595
++ V++ AG + +F +P F P ++ + ++ G+S
Sbjct 542 ----------------LLIYVVIVAGMIWMFTRIPTAFLPDEDQGVLFAQVQTPPGSSAE 585
Query 596 ATEQAVKKVEHFLSQQKGIDNYVAYVGTGSPRFYLPLDQQLPQASFAQFVVLASSLEDRN 655
T+ V + +L +++ + TG F Q +F ++ E+R
Sbjct 586 RTQVVVDSMREYLLEKESSSVSSVFTVTG---FNFAGRGQSSGMAF----IMLKPWEERP 638
Query 656 EIRHSLDQ----------QIKLLLPQARTRVSLLENGPPVGYPLQYR-VSGEDQNLVREW 704
+S+ + K + A S+LE G G+ L + +G ++ +
Sbjct 639 GGENSVFELAKRAQMHFFSFKDAMVFAFAPPSVLELGNATGFDLFLQDQAGVGHEVLLQA 698
Query 705 AQKVAKVIAENPNATNVHLDWGEPSKLIMLNIDQDRARQLGVSNTDLANFLNSSITGTVI 764
K + A+NP V + L ID ++A LGVS D+ + ++ + + +
Sbjct 699 RNKFLMLAAQNPALQRVRPNGMSDEPQYKLEIDDEKASALGVSLADINSTVSIAWGSSYV 758
Query 765 DQYREKRELIEIRLRGDQAERVDVASLASLAIPTSHGGTVPLAQIARIEYRFEDGIIWHR 824
+ + ++ + + L+G R++ L+ + G VP A ++ + +
Sbjct 759 NDFIDRGRVKRVYLQGRPDARMNPDDLSKWYVRNDKGEMVPFNAFATGKWEYGSPKLERY 818
Query 825 DRLPTITVRADMRSQLQPATVVDQMKLQMQELRRQLPNGYLIDVGGTVEESAKGQESVNA 884
+ +P + + + L + ++E+ +QLP G G E A
Sbjct 819 NGVPAMEILGEPAPGLSSGDAM----AAVEEIVKQLPKGVGYSWTGLSYEERLSGSQAPA 874
Query 885 GMPLFLAVVMTLLMVKLRSLSRAFIVFLTAPLGLIGVTLFLLLFDKPFGFVAMLGTIALS 944
L L VV L S S F V L PLG+IG L + +G +
Sbjct 875 LYALSLLVVFLCLAALYESWSIPFSVMLVVPLGVIGALLATSMRGLSNDVFFQVGLLTTI 934
Query 945 GMIMRNALILIDQIEQDVAAGHEVWTAIIDATVRRFRPILLTALAAVLAMIPLSRSIFFG 1004
G+ +NA+++++ ++ G + A I+A R RPI++T+LA +L ++PL+ S G
Sbjct 935 GLSAKNAILIVEFAKELHEQGKGIVEAAIEACRMRLRPIVMTSLAFILGVVPLAISTGAG 994
Query 1005 -----PMAVAIMGGLIVATFLTLFFLPALYAA 1031
+ ++GG++ AT L +F++P Y A
Sbjct 995 SGSQHAIGTGVIGGMVTATVLAIFWVPLFYVA 1026
Score = 37.7 bits (86), Expect = 7e-05
Identities = 29/153 (19%), Positives = 68/153 (44%), Gaps = 10/153 (7%)
Query 890 LAVVMTLLMVKLRSLSRAFIVFLTAPLGLIGVTLFLLLFDKPFGFVAMLGTIALSGMIMR 949
+ +V ++ + L++ I + P+ L+G L F + M G + G+++
Sbjct 348 ILLVFLVMYLFLQNFRATLIPTIAVPVVLLGTFGVLAAFGFSINTLTMFGMVLAIGLLVD 407
Query 950 NALILIDQIEQDVA--------AGHEVWTAIIDATVRRFRPILLTALAAVLAMIPLSRSI 1001
+A+++++ +E+ +A A + I A V ++L+A+ +A S +
Sbjct 408 DAIVVVENVERVMAEEGLSPREAARKSMGQIQGALVG--IAMVLSAVFLPMAFFGGSTGV 465
Query 1002 FFGPMAVAIMGGLIVATFLTLFFLPALYAAWFK 1034
+ ++ I+ + ++ + L PAL A K
Sbjct 466 IYRQFSITIVSAMALSVIVALILTPALCATMLK 498
Lambda K H a alpha
0.324 0.138 0.401 0.792 4.96
Gapped
Lambda K H a alpha sigma
0.267 0.0410 0.140 1.90 42.6 43.6
Effective search space used: 18160476
Database: faeb6142f80c2fbd6ba851081b9b1616.SwissProt.fasta
Posted date: May 9, 2024 3:52 PM
Number of letters in database: 19,842
Number of sequences in database: 19
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Neighboring words threshold: 11
Window for multiple hits: 40
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Data ...
