BLASTP 2.12.0+
Reference: Stephen F. Altschul, Thomas L. Madden, Alejandro A.
Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J.
Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of
protein database search programs", Nucleic Acids Res. 25:3389-3402.
Reference for composition-based statistics: Alejandro A. Schaffer,
L. Aravind, Thomas L. Madden, Sergei Shavirin, John L. Spouge, Yuri
I. Wolf, Eugene V. Koonin, and Stephen F. Altschul (2001),
"Improving the accuracy of PSI-BLAST protein database searches with
composition-based statistics and other refinements", Nucleic Acids
Res. 29:2994-3005.
Database: e2a879df533e8576c2530b0be9633ea7.SwissProt.fasta
16 sequences; 4,603 total letters
Query= ACIAD3616
Length=269
Score E
Sequences producing significant alignments: (Bits) Value
Q8Z988 2,5-diketo-D-gluconic acid reductase B [Salmonella typhi] 335 3e-120
Q8X7Z7 2,5-diketo-D-gluconic acid reductase B [Escherichia coli O... 335 3e-120
P30863 2,5-diketo-D-gluconic acid reductase B [Escherichia coli (... 334 7e-120
Q8ZRM7 2,5-diketo-D-gluconic acid reductase B [Salmonella typhimu... 333 2e-119
Q8ZH36 2,5-diketo-D-gluconic acid reductase B [Yersinia pestis] 330 3e-118
P74308 Aldo/keto reductase slr0942 [Synechocystis sp. (strain PCC... 177 3e-57
O32210 Glyoxal reductase [Bacillus subtilis (strain 168)] 172 4e-56
O34678 Uncharacterized oxidoreductase YtbE [Bacillus subtilis (st... 164 6e-53
Q8ZI40 2,5-diketo-D-gluconic acid reductase A [Yersinia pestis] 160 3e-51
P06632 2,5-diketo-D-gluconic acid reductase A [Corynebacterium sp... 159 5e-51
Q46857 2,5-diketo-D-gluconic acid reductase A [Escherichia coli (... 154 3e-49
Q1XAA8 Aldo-keto reductase family 1 member C23 [Equus caballus] 151 2e-47
P14065 Glycerol 2-dehydrogenase (NADP(+)) [Saccharomyces cerevisi... 149 9e-47
Q7TXI6 Aldo-keto reductase BQ2027_MB2996 [Mycobacterium bovis (st... 148 1e-46
P21300 Aldo-keto reductase family 1 member B7 [Mus musculus] 149 1e-46
Q95JH6 Aldo-keto reductase family 1 member C1 [Macaca fuscata fus... 149 2e-46
>Q8Z988 2,5-diketo-D-gluconic acid reductase B [Salmonella typhi]
Length=267
Score = 335 bits (859), Expect = 3e-120
Identities = 165/267 (62%), Positives = 207/267 (78%), Gaps = 0/267 (0%)
Query 2 MIVPKFGLGTFRLNDQIVIDSVKTALDVGYRAIDTAQIYDNEAQVGQAIQESGIARDQLF 61
M +P FGLGTFRL D +VI SVKTAL++GYRA+DTAQIYDNEA VGQAI ESG+ R++L+
Sbjct 1 MTIPAFGLGTFRLKDDVVIASVKTALELGYRAVDTAQIYDNEAAVGQAIAESGVPRNELY 60
Query 62 LTTKIWVDHLNSEQLIPSLKQSLQKLRTDAVNLTLIHWPAPQKGIDIAAVMQLLLQAKQQ 121
+TTKIW+++L+ ++LIPSLK+SL+KLRTD V+LTLIHWP+P + + MQ LL+AK+Q
Sbjct 61 ITTKIWIENLSKDKLIPSLKESLKKLRTDYVDLTLIHWPSPGDAVSVEEFMQALLEAKKQ 120
Query 122 GLTEHIGISNFNIAQTKTAIESIGQSHIATNQIELSPYLQNRTLVDFLKAQQIDVTSYMT 181
GLT IGISNF I + AI ++G HIATNQIELSPYLQNR +VD+ KA I +TSYMT
Sbjct 121 GLTREIGISNFTIPLMEKAIAAVGADHIATNQIELSPYLQNRKVVDWAKAHGIHITSYMT 180
Query 182 LAYGKVLHDPVLQDIASEHQASTAQIALAWALQSGYAVIPSSTKREHLISNLKAQEIQLS 241
LAYGK L D V+ IA +H A+ Q+ LAWA+ GY+VIPSST+RE+L SNL AQ++ L
Sbjct 181 LAYGKALKDEVIARIAVKHNATPVQVILAWAMGEGYSVIPSSTRRENLASNLLAQDLHLD 240
Query 242 QQDMQLIAALERNGREVDPAELAPEWD 268
+D IAAL+ N R V P LAP WD
Sbjct 241 AEDKNAIAALDCNDRLVSPEGLAPAWD 267
>Q8X7Z7 2,5-diketo-D-gluconic acid reductase B [Escherichia coli
O157:H7]
Length=267
Score = 335 bits (859), Expect = 3e-120
Identities = 167/267 (63%), Positives = 208/267 (78%), Gaps = 0/267 (0%)
Query 2 MIVPKFGLGTFRLNDQIVIDSVKTALDVGYRAIDTAQIYDNEAQVGQAIQESGIARDQLF 61
M +P FGLGTFRL D +VI SVKTAL++GYRAIDTAQIYDNEA VG AI ESG+ R +L+
Sbjct 1 MAIPAFGLGTFRLKDDVVISSVKTALELGYRAIDTAQIYDNEAAVGLAIAESGVPRHELY 60
Query 62 LTTKIWVDHLNSEQLIPSLKQSLQKLRTDAVNLTLIHWPAPQKGIDIAAVMQLLLQAKQQ 121
+TTKIW+++L+ ++LIPSLK+SLQKLRTD V+LTLIHWP+P + + MQ LL+AK++
Sbjct 61 ITTKIWIENLSKDKLIPSLKESLQKLRTDYVDLTLIHWPSPNDEVSVEEFMQALLEAKKE 120
Query 122 GLTEHIGISNFNIAQTKTAIESIGQSHIATNQIELSPYLQNRTLVDFLKAQQIDVTSYMT 181
GLT IGISNF I + AI ++G +IATNQIELSPYLQNR +V + K I +TSYMT
Sbjct 121 GLTREIGISNFTIPLMEKAIAAVGAENIATNQIELSPYLQNRKVVAWAKQHGIHITSYMT 180
Query 182 LAYGKVLHDPVLQDIASEHQASTAQIALAWALQSGYAVIPSSTKREHLISNLKAQEIQLS 241
LAYGK L D V+ IA++H A+ AQ+ LAWA+ GY+VIPSSTKRE+L SNLKAQ +QL
Sbjct 181 LAYGKALKDEVIARIAAKHNATPAQVILAWAMGEGYSVIPSSTKRENLESNLKAQNLQLD 240
Query 242 QQDMQLIAALERNGREVDPAELAPEWD 268
+D + IAAL+ N R V P LAPEWD
Sbjct 241 AEDKKAIAALDCNDRLVSPEGLAPEWD 267
>P30863 2,5-diketo-D-gluconic acid reductase B [Escherichia coli
(strain K12)]
Length=267
Score = 334 bits (857), Expect = 7e-120
Identities = 167/267 (63%), Positives = 208/267 (78%), Gaps = 0/267 (0%)
Query 2 MIVPKFGLGTFRLNDQIVIDSVKTALDVGYRAIDTAQIYDNEAQVGQAIQESGIARDQLF 61
M +P FGLGTFRL D +VI SV TAL++GYRAIDTAQIYDNEA VGQAI ESG+ R +L+
Sbjct 1 MAIPAFGLGTFRLKDDVVISSVITALELGYRAIDTAQIYDNEAAVGQAIAESGVPRHELY 60
Query 62 LTTKIWVDHLNSEQLIPSLKQSLQKLRTDAVNLTLIHWPAPQKGIDIAAVMQLLLQAKQQ 121
+TTKIW+++L+ ++LIPSLK+SLQKLRTD V+LTLIHWP+P + + MQ LL+AK+Q
Sbjct 61 ITTKIWIENLSKDKLIPSLKESLQKLRTDYVDLTLIHWPSPNDEVSVEEFMQALLEAKKQ 120
Query 122 GLTEHIGISNFNIAQTKTAIESIGQSHIATNQIELSPYLQNRTLVDFLKAQQIDVTSYMT 181
GLT IGISNF I + AI ++G +IATNQIELSPYLQNR +V + K I +TSYMT
Sbjct 121 GLTREIGISNFTIPLMEKAIAAVGAENIATNQIELSPYLQNRKVVAWAKQHGIHITSYMT 180
Query 182 LAYGKVLHDPVLQDIASEHQASTAQIALAWALQSGYAVIPSSTKREHLISNLKAQEIQLS 241
LAYGK L D V+ IA++H A+ AQ+ LAWA+ GY+VIPSSTKR++L SNLKAQ +QL
Sbjct 181 LAYGKALKDEVIARIAAKHNATPAQVILAWAMGEGYSVIPSSTKRKNLESNLKAQNLQLD 240
Query 242 QQDMQLIAALERNGREVDPAELAPEWD 268
+D + IAAL+ N R V P LAPEWD
Sbjct 241 AEDKKAIAALDCNDRLVSPEGLAPEWD 267
>Q8ZRM7 2,5-diketo-D-gluconic acid reductase B [Salmonella typhimurium
(strain LT2 / SGSC1412 / ATCC 700720)]
Length=267
Score = 333 bits (854), Expect = 2e-119
Identities = 164/267 (61%), Positives = 209/267 (78%), Gaps = 0/267 (0%)
Query 2 MIVPKFGLGTFRLNDQIVIDSVKTALDVGYRAIDTAQIYDNEAQVGQAIQESGIARDQLF 61
M +P FGLGTFRL D +VI SVKTAL++GYRA+DTAQIYDNEA VGQAI ESG+ R++L+
Sbjct 1 MTIPAFGLGTFRLKDDVVIASVKTALELGYRAVDTAQIYDNEAAVGQAIAESGVPRNELY 60
Query 62 LTTKIWVDHLNSEQLIPSLKQSLQKLRTDAVNLTLIHWPAPQKGIDIAAVMQLLLQAKQQ 121
+TTKIW+++L+ ++LIPSLK+SL+KLRTD V+LTLIHWP+P + + MQ LL+AK+Q
Sbjct 61 ITTKIWIENLSKDKLIPSLKESLKKLRTDYVDLTLIHWPSPGDAVSVEEFMQALLEAKKQ 120
Query 122 GLTEHIGISNFNIAQTKTAIESIGQSHIATNQIELSPYLQNRTLVDFLKAQQIDVTSYMT 181
GLT IGISNF I + AI ++G +IATNQIELSPYLQNR +VD+ KA I +TSYMT
Sbjct 121 GLTREIGISNFTIPLMEKAIAAVGADNIATNQIELSPYLQNRKVVDWAKAHGIHITSYMT 180
Query 182 LAYGKVLHDPVLQDIASEHQASTAQIALAWALQSGYAVIPSSTKREHLISNLKAQEIQLS 241
LAYGK L D V+ IA++H A+ AQ+ LAWA+ GY+VIPSST+RE+L S+L AQ++ L
Sbjct 181 LAYGKALKDEVIARIAAKHNATPAQVILAWAMGEGYSVIPSSTRRENLASSLLAQDLHLD 240
Query 242 QQDMQLIAALERNGREVDPAELAPEWD 268
+D IAAL+ N R V P LAP WD
Sbjct 241 AEDKNAIAALDCNDRLVSPEGLAPAWD 267
>Q8ZH36 2,5-diketo-D-gluconic acid reductase B [Yersinia pestis]
Length=267
Score = 330 bits (846), Expect = 3e-118
Identities = 169/267 (63%), Positives = 205/267 (77%), Gaps = 0/267 (0%)
Query 2 MIVPKFGLGTFRLNDQIVIDSVKTALDVGYRAIDTAQIYDNEAQVGQAIQESGIARDQLF 61
M +P FGLGTFRL DQIVIDSV AL +GYRAIDTAQIY+NEA VGQAIQESGI RD+LF
Sbjct 1 MSIPVFGLGTFRLQDQIVIDSVSQALTLGYRAIDTAQIYENEAPVGQAIQESGINRDELF 60
Query 62 LTTKIWVDHLNSEQLIPSLKQSLQKLRTDAVNLTLIHWPAPQKGIDIAAVMQLLLQAKQQ 121
+TTKIW+ +L+ ++LIPSL++S+QKL+TD V+LTLIHWP+P + +A M LL+AK
Sbjct 61 ITTKIWIANLSKDKLIPSLRESIQKLKTDYVDLTLIHWPSPNDEVSVAEFMSELLKAKGL 120
Query 122 GLTEHIGISNFNIAQTKTAIESIGQSHIATNQIELSPYLQNRTLVDFLKAQQIDVTSYMT 181
GLT IGISNF I K AI ++G IATNQIELSP LQNR +VDF K I VTSYMT
Sbjct 121 GLTRQIGISNFTIDLMKQAIAAVGAEEIATNQIELSPLLQNRNVVDFAKQNGIAVTSYMT 180
Query 182 LAYGKVLHDPVLQDIASEHQASTAQIALAWALQSGYAVIPSSTKREHLISNLKAQEIQLS 241
LAYGK L +PV++ IA +H A+ AQ+ L+WA+Q GY VIPSSTK +L SNL AQ++ L+
Sbjct 181 LAYGKALAEPVIKTIAEQHGATPAQVILSWAMQLGYGVIPSSTKAANLASNLLAQKLCLN 240
Query 242 QQDMQLIAALERNGREVDPAELAPEWD 268
DM LIA L+RN R V P LAP+WD
Sbjct 241 AADMALIATLDRNERLVSPDGLAPKWD 267
>P74308 Aldo/keto reductase slr0942 [Synechocystis sp. (strain
PCC 6803 / Kazusa)]
Length=327
Score = 177 bits (448), Expect = 3e-57
Identities = 105/287 (37%), Positives = 162/287 (56%), Gaps = 33/287 (11%)
Query 4 VPKFGLGTFRLNDQIVIDSVKTALDVGYRAIDTAQIYDNEAQVG----QAIQESGIARDQ 59
+P GLGT++ + Q+V +V+ ALD+GYR +D A IY NEA++G A + + R++
Sbjct 21 IPALGLGTWKSSPQVVGQAVEQALDLGYRHLDCAAIYGNEAEIGATLANAFTKGVVKREE 80
Query 60 LFLTTKIWVDHLNSEQLIPSLKQSLQKLRTDAVNLTLIHWPA--------PQKG------ 105
L++T+K+W + + + ++P+L+++LQ L D ++L LIHWP P+ G
Sbjct 81 LWITSKLWSNAHHPDAVLPALEKTLQDLGLDYLDLYLIHWPVVIQPDVGFPESGDQLLPF 140
Query 106 --IDIAAVMQLLLQAKQQGLTEHIGISNFNIAQTKTAIESIGQSHIATNQIELSPYLQNR 163
+ Q L +A GL HIG+SNF++ + + + S+ + A NQ+EL PYLQ
Sbjct 141 TPASLEGTWQALEKAVDLGLCHHIGVSNFSLKKLEMVL-SMARIPPAVNQVELHPYLQQS 199
Query 164 TLVDFLKAQQIDVTSYMTLAYG------------KVLHDPVLQDIASEHQASTAQIALAW 211
L+ F +Q I +T+Y L G K+L DPV+ IA+E S AQ+ LAW
Sbjct 200 DLLTFANSQNILLTAYSPLGSGDRPAAFQQAAEPKLLTDPVINGIAAEQGCSAAQVLLAW 259
Query 212 ALQSGYAVIPSSTKREHLISNLKAQEIQLSQQDMQLIAALERNGREV 258
A+Q G IP S E L NL+A +I L+ +M IA L+R+ R V
Sbjct 260 AIQRGTVTIPKSVNPERLEQNLRAADITLTDSEMAKIALLDRHYRYV 306
>O32210 Glyoxal reductase [Bacillus subtilis (strain 168)]
Length=276
Score = 172 bits (436), Expect = 4e-56
Identities = 96/254 (38%), Positives = 145/254 (57%), Gaps = 5/254 (2%)
Query 4 VPKFGLGTFRL-NDQIVIDSVKTALDVGYRAIDTAQIYDNEAQVGQAIQESGIARDQLFL 62
+P FGLG F++ N +SVK A+ GYR+IDTA IY NE VG I+ESG+AR++LF+
Sbjct 17 MPWFGLGVFKVENGNEATESVKAAIKNGYRSIDTAAIYKNEEGVGIGIKESGVAREELFI 76
Query 63 TTKIWVDHLNSEQLIPSLKQSLQKLRTDAVNLTLIHWPAPQKGIDIAAVMQLLLQAKQQG 122
T+K+W + E + + ++SL++L+ D ++L LIHWP K D ++ L + G
Sbjct 77 TSKVWNEDQGYETTLAAFEKSLERLQLDYLDLYLIHWPGKDKYKDTWRALEKLY---KDG 133
Query 123 LTEHIGISNFNIAQTKTAIESIGQSHIATNQIELSPYLQNRTLVDFLKAQQIDVTSYMTL 182
IG+SNF + + ++ + NQ+E P L + L D+ K Q I + ++ L
Sbjct 134 KIRAIGVSNFQVHHLEELLKD-AEIKPMVNQVEFHPRLTQKELRDYCKGQGIQLEAWSPL 192
Query 183 AYGKVLHDPVLQDIASEHQASTAQIALAWALQSGYAVIPSSTKREHLISNLKAQEIQLSQ 242
G++L + VL IA +H S AQ+ L W LQ G IP S K +I N + +LSQ
Sbjct 193 MQGQLLDNEVLTQIAEKHNKSVAQVILRWDLQHGVVTIPKSIKEHRIIENADIFDFELSQ 252
Query 243 QDMQLIAALERNGR 256
+DM I AL ++ R
Sbjct 253 EDMDKIDALNKDER 266
>O34678 Uncharacterized oxidoreductase YtbE [Bacillus subtilis
(strain 168)]
Length=280
Score = 164 bits (415), Expect = 6e-53
Identities = 97/258 (38%), Positives = 147/258 (57%), Gaps = 9/258 (3%)
Query 4 VPKFGLGTFRLND-QIVIDSVKTALDVGYRAIDTAQIYDNEAQVGQAI----QESGIARD 58
+P FGLG F++ + ++++VKTA+ GYR+IDTA IY NEA VG+ I +E+GI+R+
Sbjct 17 MPWFGLGVFQVEEGSELVNAVKTAIVHGYRSIDTAAIYGNEAGVGEGIREGIEEAGISRE 76
Query 59 QLFLTTKIWVDHLNSEQLIPSLKQSLQKLRTDAVNLTLIHWPAPQKGIDIAAVMQLLLQA 118
LF+T+K+W L E+ + + + SL KL D ++L LIHWP K + ++ L +
Sbjct 77 DLFITSKVWNADLGYEETLAAFETSLSKLGLDYLDLYLIHWPVEGKYKEAWRALETLYK- 135
Query 119 KQQGLTEHIGISNFNIAQTKTAIESIGQSHIATNQIELSPYLQNRTLVDFLKAQQIDVTS 178
+G + IG+SNF I + + + + NQ+E P L + L+ + + Q I + +
Sbjct 136 --EGRIKAIGVSNFQIHHLEDLMTA-AEIKPMINQVEFHPRLTQKELIRYCQNQGIQMEA 192
Query 179 YMTLAYGKVLHDPVLQDIASEHQASTAQIALAWALQSGYAVIPSSTKREHLISNLKAQEI 238
+ L G++L PVL DIA + S AQI L W LQ G IP STK + N +
Sbjct 193 WSPLMQGQLLDHPVLADIAQTYNKSVAQIILRWDLQHGIITIPKSTKEHRIKENASVFDF 252
Query 239 QLSQQDMQLIAALERNGR 256
+L+Q DM I AL N R
Sbjct 253 ELTQDDMNRIDALNENLR 270
>Q8ZI40 2,5-diketo-D-gluconic acid reductase A [Yersinia pestis]
Length=277
Score = 160 bits (404), Expect = 3e-51
Identities = 94/252 (37%), Positives = 148/252 (59%), Gaps = 6/252 (2%)
Query 3 IVPKFGLGTFRLNDQIVIDSVKTALDVGYRAIDTAQIYDNEAQVGQAIQESGIARDQLFL 62
++P+ GLG ++ + Q +V AL+VGYR+IDTA IY NE VG+A++ + +ARD+LF+
Sbjct 14 LMPQLGLGVWQASIQETELAVSKALEVGYRSIDTAAIYKNEEGVGKALKAAAVARDELFI 73
Query 63 TTKIWVDHLNSEQLIPSLKQSLQKLRTDAVNLTLIHWPAPQKGIDIAAVMQLLLQAKQQG 122
TTK+W D ++ Q +L+ SLQKL+ D V+L LIHWP P++ ++A + L+ K+QG
Sbjct 74 TTKLWNDDQHNPQ--QALETSLQKLQLDYVDLYLIHWPDPKQDHYVSAWRE-LVTLKEQG 130
Query 123 LTEHIGISNFNIAQTKTAIESIGQSHIATNQIELSPYLQNRTLVDFLKAQQIDVTSYMTL 182
L IG+ NF+I + I+ G + NQIEL P LQ R L + I S+ L
Sbjct 131 LIRSIGVCNFHIPHLQRLIDETGIAP-TVNQIELHPLLQQRQLHAWNATHHIATESWSPL 189
Query 183 AYG--KVLHDPVLQDIASEHQASTAQIALAWALQSGYAVIPSSTKREHLISNLKAQEIQL 240
A G V +++ +A ++ + AQI + W L SG VIP S + N + + +L
Sbjct 190 AQGGKGVFDQEIIRKLAQQYNKTPAQIVIRWHLDSGLIVIPKSVTPARIRENFEVFDFKL 249
Query 241 SQQDMQLIAALE 252
++++ I L+
Sbjct 250 QKEELLAITKLD 261
>P06632 2,5-diketo-D-gluconic acid reductase A [Corynebacterium
sp. (strain ATCC 31090)]
Length=278
Score = 159 bits (402), Expect = 5e-51
Identities = 92/251 (37%), Positives = 137/251 (55%), Gaps = 4/251 (2%)
Query 4 VPKFGLGTFRLNDQIVIDSVKTALDVGYRAIDTAQIYDNEAQVGQAIQESGIARDQLFLT 63
+P+ G G F++ +V+ AL+VGYR IDTA IY NE VG AI SGIARD LF+T
Sbjct 14 IPQLGYGVFKVPPADTQRAVEEALEVGYRHIDTAAIYGNEEGVGAAIAASGIARDDLFIT 73
Query 64 TKIWVDHLNSEQLIPSLKQSLQKLRTDAVNLTLIHWPAPQKGIDIAAVMQLLLQAKQQGL 123
TK+W D + ++ ++ +SL KL D V+L L+HWP P + A + +++ + GL
Sbjct 74 TKLWNDRHDGDEPAAAIAESLAKLALDQVDLYLVHWPTPAADNYVHA-WEKMIELRAAGL 132
Query 124 TEHIGISNFNIAQTKTAIESIGQSHIATNQIELSPYLQNRTLVDFLKAQQIDVTSYMTLA 183
T IG+SN + + + + G A NQIEL P Q R + D+ A + + S+ L
Sbjct 133 TRSIGVSNHLVPHLERIVAATGVVP-AVNQIELHPAYQQREITDWAAAHDVKIESWGPLG 191
Query 184 YGK--VLHDPVLQDIASEHQASTAQIALAWALQSGYAVIPSSTKREHLISNLKAQEIQLS 241
GK + + A+ H + AQ L W LQ G+ V P S +RE L NL + L+
Sbjct 192 QGKYDLFGAEPVTAAAAAHGKTPAQAVLRWHLQKGFVVFPKSVRRERLEENLDVFDFDLT 251
Query 242 QQDMQLIAALE 252
++ I A++
Sbjct 252 DTEIAAIDAMD 262
>Q46857 2,5-diketo-D-gluconic acid reductase A [Escherichia coli
(strain K12)]
Length=275
Score = 154 bits (390), Expect = 3e-49
Identities = 88/257 (34%), Positives = 151/257 (59%), Gaps = 8/257 (3%)
Query 3 IVPKFGLGTFRLNDQIVIDSVKTALDVGYRAIDTAQIYDNEAQVGQAIQESGIARDQLFL 62
++P+ GLG ++ +++ VI +++ AL+VGYR+IDTA Y NE VG+A++ + + R++LF+
Sbjct 14 VMPQLGLGVWQASNEEVITAIQKALEVGYRSIDTAAAYKNEEGVGKALKNASVNREELFI 73
Query 63 TTKIWVDHLNSEQLIPSLKQSLQKLRTDAVNLTLIHWPAPQKGID-IAAVMQLLLQAKQQ 121
TTK+W D + ++ +L SL+KL+ D ++L L+HWP P ID + +++ +++
Sbjct 74 TTKLWND--DHKRPREALLDSLKKLQLDYIDLYLMHWPVP--AIDHYVEAWKGMIELQKE 129
Query 122 GLTEHIGISNFNIAQTKTAIESIGQSHIATNQIELSPYLQNRTLVDFLKAQQIDVTSYMT 181
GL + IG+ NF I + I+ G + + NQIEL P +Q R L + +I S+
Sbjct 130 GLIKSIGVCNFQIHHLQRLIDETGVTPV-INQIELHPLMQQRQLHAWNATHKIQTESWSP 188
Query 182 LAYG--KVLHDPVLQDIASEHQASTAQIALAWALQSGYAVIPSSTKREHLISNLKAQEIQ 239
LA G V V++D+A ++ + AQI + W L SG VIP S + N + +
Sbjct 189 LAQGGKGVFDQKVIRDLADKYGKTPAQIVIRWHLDSGLVVIPKSVTPSRIAENFDVWDFR 248
Query 240 LSQQDMQLIAALERNGR 256
L + ++ IA L++ R
Sbjct 249 LDKDELGEIAKLDQGKR 265
>Q1XAA8 Aldo-keto reductase family 1 member C23 [Equus caballus]
Length=322
Score = 151 bits (381), Expect = 2e-47
Identities = 93/286 (33%), Positives = 152/286 (53%), Gaps = 35/286 (12%)
Query 8 GLGTFRLND---QIVIDSVKTALDVGYRAIDTAQIYDNEAQVGQAI----QESGIARDQL 60
G GT+ N+ +++ K+A+D G+R ID A +YDNE +VG AI Q+ + R+ +
Sbjct 20 GFGTYAPNEVPKSKAVEATKSAIDAGFRHIDCAHLYDNEKEVGLAIRSKIQDGTVKREDI 79
Query 61 FLTTKIWVDHLNSEQLIPSLKQSLQKLRTDAVNLTLIHWPAPQKG--------------- 105
F T+K+W L + + P+L++SL+ L+ D V+L +IH+P K
Sbjct 80 FCTSKLWATSLRLQLVRPALEKSLKNLQLDYVDLYIIHFPVAVKPGEEHLPQDEQGRMIF 139
Query 106 --IDIAAVMQLLLQAKQQGLTEHIGISNFNIAQTKTAIESIGQSHIAT-NQIELSPYLQN 162
+D+ A + + + K GLT+ IG+SNFN Q + + G H NQ+E PYL
Sbjct 140 DTVDLCATWEAMEKCKDAGLTKSIGVSNFNRRQLEMILNKPGLKHKPVCNQVECHPYLNQ 199
Query 163 RTLVDFLKAQQIDVTSYMTLAYGK----------VLHDPVLQDIASEHQASTAQIALAWA 212
L+DF K++ I + +Y L + +L DPVL +A +++ + A IAL +
Sbjct 200 SKLLDFCKSKDIVLVAYSALGSQREHWIDQSSPVLLEDPVLCAMAKKYKRTPALIALRYQ 259
Query 213 LQSGYAVIPSSTKREHLISNLKAQEIQLSQQDMQLIAALERNGREV 258
LQ G V+ S + + N++A QL+ +DM+++ L RN R V
Sbjct 260 LQRGVVVLAKSYNEKRIKENVQAFGFQLTSEDMKVLDGLNRNLRYV 305
>P14065 Glycerol 2-dehydrogenase (NADP(+)) [Saccharomyces cerevisiae
(strain ATCC 204508 / S288c)]
Length=312
Score = 149 bits (376), Expect = 9e-47
Identities = 92/282 (33%), Positives = 150/282 (53%), Gaps = 32/282 (11%)
Query 4 VPKFGLGTFRLNDQIVIDSVKTALDVGYRAIDTAQIYDNEAQVGQAIQESGIARDQLFLT 63
+P+ GLGT++ + +V TAL GYR IDTA IY NE QVGQAI++SG+ R+++F+T
Sbjct 20 IPQIGLGTWQSKENDAYKAVLTALKDGYRHIDTAAIYRNEDQVGQAIKDSGVPREEIFVT 79
Query 64 TKIWVDHLNSEQLIPSLKQSLQKLRTDAVNLTLIHWPA--------------------PQ 103
TK+W + ++ +L QSL++L D V+L L+HWPA
Sbjct 80 TKLWCTQHHEPEV--ALDQSLKRLGLDYVDLYLMHWPARLDPAYIKNEDILSVPTKKDGS 137
Query 104 KGIDIA-----AVMQLLLQAKQQGLTEHIGISNFNIAQTKTAIESIGQSHI-ATNQIELS 157
+ +DI +L+ + + G T+ +G+SNF+I K + S G A NQ+E+
Sbjct 138 RAVDITNWNFIKTWELMQELPKTGKTKAVGVSNFSINNLKDLLASQGNKLTPAANQVEIH 197
Query 158 PYLQNRTLVDFLKAQQIDVTSYMTLAY--GKVLHDPVLQDIASEHQASTAQIALAWALQS 215
P L L++F K++ I V +Y L +L +PV+ +IA ++ + ++W +Q
Sbjct 198 PLLPQDELINFCKSKGIVVEAYSPLGSTDAPLLKEPVILEIAKKNNVQPGHVVISWHVQR 257
Query 216 GYAVIPSSTKREHLISNLKAQEIQLSQQDMQLIAALERNGRE 257
GY V+P S + + +N K LS +D + I + + E
Sbjct 258 GYVVLPKSVNPDRIKTNRKI--FTLSTEDFEAINNISKEKGE 297
>Q7TXI6 Aldo-keto reductase BQ2027_MB2996 [Mycobacterium bovis
(strain ATCC BAA-935 / AF2122/97)]
Length=282
Score = 148 bits (373), Expect = 1e-46
Identities = 92/253 (36%), Positives = 134/253 (53%), Gaps = 2/253 (1%)
Query 4 VPKFGLGTFRLNDQIVIDSVKTALDVGYRAIDTAQIYDNEAQVGQAIQESGIARDQLFLT 63
+P GLG L+D +V AL++G R IDTA Y NEA VG+AI SG+AR++LF+T
Sbjct 21 MPVLGLGVAELSDDETERAVSAALEIGCRLIDTAYAYGNEAAVGRAIAASGVAREELFVT 80
Query 64 TKIWVDHLNSEQLIPSLKQSLQKLRTDAVNLTLIHWPAPQKGIDIAAVMQLLLQAKQQGL 123
TK+ + + + SL +L D V+L LIHWPAP G + A ++Q++ +G
Sbjct 81 TKLATPDQGFTRSQEACRASLDRLGLDYVDLYLIHWPAPPVGKYVDA-WGGMIQSRGEGH 139
Query 124 TEHIGISNFNIAQTKTAIESIGQSHIATNQIELSPYLQNRTLVDFLKAQQIDVTSYMTLA 183
IG+SNF + I+ + A NQIEL P L L + SY LA
Sbjct 140 ARSIGVSNFTAEHIENLIDLTFVTP-AVNQIELHPLLNQDELRKANAQHTVVTQSYCPLA 198
Query 184 YGKVLHDPVLQDIASEHQASTAQIALAWALQSGYAVIPSSTKREHLISNLKAQEIQLSQQ 243
G++L +P + IASE+ + AQ+ L W LQ G AV+ S + E + SN + +L+ +
Sbjct 199 LGRLLDNPTVTSIASEYVKTPAQVLLRWNLQLGNAVVVRSARPERIASNFDVFDFELAAE 258
Query 244 DMQLIAALERNGR 256
M + L R
Sbjct 259 HMDALGGLNDGTR 271
>P21300 Aldo-keto reductase family 1 member B7 [Mus musculus]
Length=316
Score = 149 bits (375), Expect = 1e-46
Identities = 97/300 (32%), Positives = 153/300 (51%), Gaps = 38/300 (13%)
Query 4 VPKFGLGTFRLNDQIVIDSVKTALDVGYRAIDTAQIYDNEAQVGQAIQ----ESGIARDQ 59
+P GLGT++ + V ++VK A+D GYR ID A +Y NE +VG+AIQ E+ + R+
Sbjct 13 MPLVGLGTWKSSPGQVKEAVKAAIDAGYRHIDCAYVYHNENEVGEAIQEKIKENAVKRED 72
Query 60 LFLTTKIWVDHLNSEQLIPSLKQSLQKLRTDAVNLTLIHW-----------PAPQKG--- 105
LF+ +K+W + + + +L L+ D ++L L+HW P KG
Sbjct 73 LFIVSKLWATFFEKSLVKKAFQNTLSDLKLDYLDLYLVHWPQGFQAGNALLPKDNKGKVL 132
Query 106 ------IDIAAVMQLLLQAKQQGLTEHIGISNFNIAQTKTAIESIGQSH-IATNQIELSP 158
+D M+ L+ QGL + +GISNFN Q + + G H TNQIE P
Sbjct 133 LSKSTFLDAWEAMEELV---DQGLVKALGISNFNHFQIERLLNKPGLKHKPVTNQIESHP 189
Query 159 YLQNRTLVDFLKAQQIDVTSYMTLA-----YGK-----VLHDPVLQDIASEHQASTAQIA 208
YL L+ + +++ I VT+Y L Y K V+ P +++IA++H+ + AQ+
Sbjct 190 YLTQEKLIQYCQSKGIAVTAYSPLGSPDRPYAKPEDPVVMEIPKIKEIAAKHKKTVAQVL 249
Query 209 LAWALQSGYAVIPSSTKREHLISNLKAQEIQLSQQDMQLIAALERNGREVDPAELAPEWD 268
+ + +Q VIP S + NL+ + QLS++DM I + RN R D + E D
Sbjct 250 IRFHVQRNVVVIPKSVTPSRIQENLQVFDFQLSEEDMAAILSFNRNWRACDLLDARTEED 309
>Q95JH6 Aldo-keto reductase family 1 member C1 [Macaca fuscata
fuscata]
Length=323
Score = 149 bits (375), Expect = 2e-46
Identities = 93/289 (32%), Positives = 151/289 (52%), Gaps = 36/289 (12%)
Query 4 VPKFGLGTF---RLNDQIVIDSVKTALDVGYRAIDTAQIYDNEAQVGQAIQ----ESGIA 56
+P G GT+ + I++ K A++ G+R ID+A +Y+NE VG AI+ + +
Sbjct 16 MPVLGFGTYAPAEVPKNKAIEATKLAIEAGFRHIDSAHLYNNEEYVGLAIRSKIADGTVK 75
Query 57 RDQLFLTTKIWVDHLNSEQLIPSLKQSLQKLRTDAVNLTLIHWPAPQKG----------- 105
R+ +F T+K+W + E + P+L++SL+ L+ D V+L LIH+P K
Sbjct 76 REDIFYTSKLWCNSHRPEFVRPALERSLKNLQLDYVDLYLIHFPVSLKPGEELIPKDENG 135
Query 106 ------IDIAAVMQLLLQAKQQGLTEHIGISNFNIAQTKTAIESIGQSHIAT-NQIELSP 158
+D+ A + + + K GL + IG+SNFN Q + + G + NQ+E P
Sbjct 136 KLLFDTVDLCATWEAMEKCKDAGLAKSIGVSNFNRRQLEMILNKPGLKYKPVCNQVECHP 195
Query 159 YLQNRTLVDFLKAQQIDVTSYMTLAYGK-----------VLHDPVLQDIASEHQASTAQI 207
YL R L+DF K++ I + +Y L + +L DPVL +A +H+ + A I
Sbjct 196 YLNQRKLLDFCKSKDIVLVAYSALGSHREKPWVDQNSPVLLEDPVLCALAKKHKRTPALI 255
Query 208 ALAWALQSGYAVIPSSTKREHLISNLKAQEIQLSQQDMQLIAALERNGR 256
AL + LQ G V+ S + + N+K E QL+ +DM+ I L+RN R
Sbjct 256 ALRYQLQRGVVVLAKSYNEQRIRENMKVFEFQLTSEDMKAIDGLDRNIR 304
Lambda K H a alpha
0.319 0.132 0.373 0.792 4.96
Gapped
Lambda K H a alpha sigma
0.267 0.0410 0.140 1.90 42.6 43.6
Effective search space used: 877275
Database: e2a879df533e8576c2530b0be9633ea7.SwissProt.fasta
Posted date: May 9, 2024 1:50 AM
Number of letters in database: 4,603
Number of sequences in database: 16
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Neighboring words threshold: 11
Window for multiple hits: 40
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Data ...
