Comparative Genomics

ACIAD3587 / SwissProt Alignments

BLASTP 2.12.0+


Reference: Stephen F. Altschul, Thomas L. Madden, Alejandro A.
Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J.
Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of
protein database search programs", Nucleic Acids Res. 25:3389-3402.


Reference for composition-based statistics: Alejandro A. Schaffer,
L. Aravind, Thomas L. Madden, Sergei Shavirin, John L. Spouge, Yuri
I. Wolf, Eugene V. Koonin, and Stephen F. Altschul (2001),
"Improving the accuracy of PSI-BLAST protein database searches with
composition-based statistics and other refinements", Nucleic Acids
Res. 29:2994-3005.



Database: 30a6676c21fdff631589a62bc2f052c8.SwissProt.fasta
           25 sequences; 6,754 total letters



Query= ACIAD3587

Length=240
                                                                      Score     E
Sequences producing significant alignments:                          (Bits)  Value

Q6F6U0 Phosphoribosylaminoimidazole-succinocarboxamide synthase [...  478     1e-177
B0VA00 Phosphoribosylaminoimidazole-succinocarboxamide synthase [...  450     2e-166
A3MA70 Phosphoribosylaminoimidazole-succinocarboxamide synthase [...  450     2e-166
B0VPX5 Phosphoribosylaminoimidazole-succinocarboxamide synthase [...  450     2e-166
B2I2E3 Phosphoribosylaminoimidazole-succinocarboxamide synthase [...  450     2e-166
B7I289 Phosphoribosylaminoimidazole-succinocarboxamide synthase [...  450     2e-166
A5WHC5 Phosphoribosylaminoimidazole-succinocarboxamide synthase [...  384     4e-140
Q4FVD4 Phosphoribosylaminoimidazole-succinocarboxamide synthase [...  372     1e-135
Q1QEF9 Phosphoribosylaminoimidazole-succinocarboxamide synthase [...  371     4e-135
Q4ZW72 Phosphoribosylaminoimidazole-succinocarboxamide synthase [...  353     3e-128
Q87Y59 Phosphoribosylaminoimidazole-succinocarboxamide synthase [...  352     2e-127
Q48LD2 Phosphoribosylaminoimidazole-succinocarboxamide synthase [...  351     2e-127
Q3KGI9 Phosphoribosylaminoimidazole-succinocarboxamide synthase [...  348     3e-126
C3KED7 Phosphoribosylaminoimidazole-succinocarboxamide synthase [...  348     3e-126
A6VX88 Phosphoribosylaminoimidazole-succinocarboxamide synthase [...  348     6e-126
P0A7D7 Phosphoribosylaminoimidazole-succinocarboxamide synthase [...  315     3e-113
P12046 Phosphoribosylaminoimidazole-succinocarboxamide synthase [...  229     3e-79 
Q07296 Phosphoribosylaminoimidazole-succinocarboxamide synthase [...  204     2e-69 
O68830 Phosphoribosylaminoimidazole-succinocarboxamide synthase [...  196     3e-66 
Q9R7D5 Phosphoribosylaminoimidazole-succinocarboxamide synthase [...  195     7e-66 
P51583 Phosphoribosylaminoimidazole carboxylase / Phosphoribosyla...  124     1e-36 
P22234 Phosphoribosylaminoimidazole carboxylase / Phosphoribosyla...  124     2e-36 
Q9I7S8 Phosphoribosylaminoimidazole-succinocarboxamide synthase /...  115     2e-33 
P38024 Phosphoribosylaminoimidazole-succinocarboxamide synthase /...  109     4e-31 
P9WHN1 Phosphoribosylaminoimidazole-succinocarboxamide synthase [...  66.6    3e-16 


>Q6F6U0 Phosphoribosylaminoimidazole-succinocarboxamide synthase 
[Acinetobacter baylyi (strain ATCC 33305 / BD413 / ADP1)]
Length=239

 Score = 478 bits (1231),  Expect = 1e-177
 Identities = 239/239 (100%), Positives = 239/239 (100%), Gaps = 0/239 (0%)

Query  1    MLKQTLLYTGKAKSVYETDSADHLILVFRDDASAFNGEKIEQLDRKGKVNNRFNAFIMEK  60
            MLKQTLLYTGKAKSVYETDSADHLILVFRDDASAFNGEKIEQLDRKGKVNNRFNAFIMEK
Sbjct  1    MLKQTLLYTGKAKSVYETDSADHLILVFRDDASAFNGEKIEQLDRKGKVNNRFNAFIMEK  60

Query  61   LAEAGIETHFEKLLTPNEVLVKKLNMIPVECVIRNYAAGSLCRRLGVEEGKQLTPPTFEL  120
            LAEAGIETHFEKLLTPNEVLVKKLNMIPVECVIRNYAAGSLCRRLGVEEGKQLTPPTFEL
Sbjct  61   LAEAGIETHFEKLLTPNEVLVKKLNMIPVECVIRNYAAGSLCRRLGVEEGKQLTPPTFEL  120

Query  121  FFKDDALGDPMVNESQAIALGWATADQLEKMKELTYQVNDVLKALFDAGNMILVDFKLEF  180
            FFKDDALGDPMVNESQAIALGWATADQLEKMKELTYQVNDVLKALFDAGNMILVDFKLEF
Sbjct  121  FFKDDALGDPMVNESQAIALGWATADQLEKMKELTYQVNDVLKALFDAGNMILVDFKLEF  180

Query  181  GVFHDRIVLGDEFSPDGCRLWDKDTKKKLDKDRFRQGLGGVVEAYEEVAARLGINLDDI  239
            GVFHDRIVLGDEFSPDGCRLWDKDTKKKLDKDRFRQGLGGVVEAYEEVAARLGINLDDI
Sbjct  181  GVFHDRIVLGDEFSPDGCRLWDKDTKKKLDKDRFRQGLGGVVEAYEEVAARLGINLDDI  239


>B0VA00 Phosphoribosylaminoimidazole-succinocarboxamide synthase 
[Acinetobacter baumannii (strain AYE)]
Length=239

 Score = 450 bits (1158),  Expect = 2e-166
 Identities = 223/239 (93%), Positives = 232/239 (97%), Gaps = 0/239 (0%)

Query  1    MLKQTLLYTGKAKSVYETDSADHLILVFRDDASAFNGEKIEQLDRKGKVNNRFNAFIMEK  60
            MLKQTLLYTGKAKSVYETD+ADHLILVFRDDASAFNGEKIEQLDRKGKVNNRFNAFIMEK
Sbjct  1    MLKQTLLYTGKAKSVYETDNADHLILVFRDDASAFNGEKIEQLDRKGKVNNRFNAFIMEK  60

Query  61   LAEAGIETHFEKLLTPNEVLVKKLNMIPVECVIRNYAAGSLCRRLGVEEGKQLTPPTFEL  120
            LAEAGIETHFEKLL+P EVLVKKL MIPVECVIRNYAAGSLCRRLGVEEGK+LTPPTFEL
Sbjct  61   LAEAGIETHFEKLLSPTEVLVKKLQMIPVECVIRNYAAGSLCRRLGVEEGKELTPPTFEL  120

Query  121  FFKDDALGDPMVNESQAIALGWATADQLEKMKELTYQVNDVLKALFDAGNMILVDFKLEF  180
            F+KDD LGDPMVNESQAIALGWATA+QLE+MK LTY+VNDVLKALF  GNMILVDFKLEF
Sbjct  121  FYKDDGLGDPMVNESQAIALGWATAEQLEQMKVLTYKVNDVLKALFAEGNMILVDFKLEF  180

Query  181  GVFHDRIVLGDEFSPDGCRLWDKDTKKKLDKDRFRQGLGGVVEAYEEVAARLGINLDDI  239
            GVFHDRIVLGDEFSPDGCRLWDKDTKKKLDKDRFRQGLGGVVEAYEEVAARLG++L DI
Sbjct  181  GVFHDRIVLGDEFSPDGCRLWDKDTKKKLDKDRFRQGLGGVVEAYEEVAARLGVDLSDI  239


>A3MA70 Phosphoribosylaminoimidazole-succinocarboxamide synthase 
[Acinetobacter baumannii (strain ATCC 17978 / CIP 53.77 / 
LMG 1025 / NCDC KC755 / 5377)]
Length=239

 Score = 450 bits (1158),  Expect = 2e-166
 Identities = 223/239 (93%), Positives = 232/239 (97%), Gaps = 0/239 (0%)

Query  1    MLKQTLLYTGKAKSVYETDSADHLILVFRDDASAFNGEKIEQLDRKGKVNNRFNAFIMEK  60
            MLKQTLLYTGKAKSVYETD+ADHLILVFRDDASAFNGEKIEQLDRKGKVNNRFNAFIMEK
Sbjct  1    MLKQTLLYTGKAKSVYETDNADHLILVFRDDASAFNGEKIEQLDRKGKVNNRFNAFIMEK  60

Query  61   LAEAGIETHFEKLLTPNEVLVKKLNMIPVECVIRNYAAGSLCRRLGVEEGKQLTPPTFEL  120
            LAEAGIETHFEKLL+P EVLVKKL MIPVECVIRNYAAGSLCRRLGVEEGK+LTPPTFEL
Sbjct  61   LAEAGIETHFEKLLSPTEVLVKKLQMIPVECVIRNYAAGSLCRRLGVEEGKELTPPTFEL  120

Query  121  FFKDDALGDPMVNESQAIALGWATADQLEKMKELTYQVNDVLKALFDAGNMILVDFKLEF  180
            F+KDD LGDPMVNESQAIALGWATA+QLE+MK LTY+VNDVLKALF  GNMILVDFKLEF
Sbjct  121  FYKDDGLGDPMVNESQAIALGWATAEQLEQMKVLTYKVNDVLKALFAEGNMILVDFKLEF  180

Query  181  GVFHDRIVLGDEFSPDGCRLWDKDTKKKLDKDRFRQGLGGVVEAYEEVAARLGINLDDI  239
            GVFHDRIVLGDEFSPDGCRLWDKDTKKKLDKDRFRQGLGGVVEAYEEVAARLG++L DI
Sbjct  181  GVFHDRIVLGDEFSPDGCRLWDKDTKKKLDKDRFRQGLGGVVEAYEEVAARLGVDLSDI  239


>B0VPX5 Phosphoribosylaminoimidazole-succinocarboxamide synthase 
[Acinetobacter baumannii (strain SDF)]
Length=239

 Score = 450 bits (1158),  Expect = 2e-166
 Identities = 223/239 (93%), Positives = 232/239 (97%), Gaps = 0/239 (0%)

Query  1    MLKQTLLYTGKAKSVYETDSADHLILVFRDDASAFNGEKIEQLDRKGKVNNRFNAFIMEK  60
            MLKQTLLYTGKAKSVYETD+ADHLILVFRDDASAFNGEKIEQLDRKGKVNNRFNAFIMEK
Sbjct  1    MLKQTLLYTGKAKSVYETDNADHLILVFRDDASAFNGEKIEQLDRKGKVNNRFNAFIMEK  60

Query  61   LAEAGIETHFEKLLTPNEVLVKKLNMIPVECVIRNYAAGSLCRRLGVEEGKQLTPPTFEL  120
            LAEAGIETHFEKLL+P EVLVKKL MIPVECVIRNYAAGSLCRRLGVEEGK+LTPPTFEL
Sbjct  61   LAEAGIETHFEKLLSPTEVLVKKLQMIPVECVIRNYAAGSLCRRLGVEEGKELTPPTFEL  120

Query  121  FFKDDALGDPMVNESQAIALGWATADQLEKMKELTYQVNDVLKALFDAGNMILVDFKLEF  180
            F+KDD LGDPMVNESQAIALGWATA+QLE+MK LTY+VNDVLKALF  GNMILVDFKLEF
Sbjct  121  FYKDDGLGDPMVNESQAIALGWATAEQLEQMKVLTYKVNDVLKALFAEGNMILVDFKLEF  180

Query  181  GVFHDRIVLGDEFSPDGCRLWDKDTKKKLDKDRFRQGLGGVVEAYEEVAARLGINLDDI  239
            GVFHDRIVLGDEFSPDGCRLWDKDTKKKLDKDRFRQGLGGVVEAYEEVAARLG++L DI
Sbjct  181  GVFHDRIVLGDEFSPDGCRLWDKDTKKKLDKDRFRQGLGGVVEAYEEVAARLGVDLSDI  239


>B2I2E3 Phosphoribosylaminoimidazole-succinocarboxamide synthase 
[Acinetobacter baumannii (strain ACICU)]
Length=239

 Score = 450 bits (1158),  Expect = 2e-166
 Identities = 223/239 (93%), Positives = 232/239 (97%), Gaps = 0/239 (0%)

Query  1    MLKQTLLYTGKAKSVYETDSADHLILVFRDDASAFNGEKIEQLDRKGKVNNRFNAFIMEK  60
            MLKQTLLYTGKAKSVYETD+ADHLILVFRDDASAFNGEKIEQLDRKGKVNNRFNAFIMEK
Sbjct  1    MLKQTLLYTGKAKSVYETDNADHLILVFRDDASAFNGEKIEQLDRKGKVNNRFNAFIMEK  60

Query  61   LAEAGIETHFEKLLTPNEVLVKKLNMIPVECVIRNYAAGSLCRRLGVEEGKQLTPPTFEL  120
            LAEAGIETHFEKLL+P EVLVKKL MIPVECVIRNYAAGSLCRRLGVEEGK+LTPPTFEL
Sbjct  61   LAEAGIETHFEKLLSPTEVLVKKLQMIPVECVIRNYAAGSLCRRLGVEEGKELTPPTFEL  120

Query  121  FFKDDALGDPMVNESQAIALGWATADQLEKMKELTYQVNDVLKALFDAGNMILVDFKLEF  180
            F+KDD LGDPMVNESQAIALGWATA+QLE+MK LTY+VNDVLKALF  GNMILVDFKLEF
Sbjct  121  FYKDDGLGDPMVNESQAIALGWATAEQLEQMKVLTYKVNDVLKALFAEGNMILVDFKLEF  180

Query  181  GVFHDRIVLGDEFSPDGCRLWDKDTKKKLDKDRFRQGLGGVVEAYEEVAARLGINLDDI  239
            GVFHDRIVLGDEFSPDGCRLWDKDTKKKLDKDRFRQGLGGVVEAYEEVAARLG++L DI
Sbjct  181  GVFHDRIVLGDEFSPDGCRLWDKDTKKKLDKDRFRQGLGGVVEAYEEVAARLGVDLSDI  239


>B7I289 Phosphoribosylaminoimidazole-succinocarboxamide synthase 
[Acinetobacter baumannii (strain AB0057)]
Length=239

 Score = 450 bits (1158),  Expect = 2e-166
 Identities = 223/239 (93%), Positives = 232/239 (97%), Gaps = 0/239 (0%)

Query  1    MLKQTLLYTGKAKSVYETDSADHLILVFRDDASAFNGEKIEQLDRKGKVNNRFNAFIMEK  60
            MLKQTLLYTGKAKSVYETD+ADHLILVFRDDASAFNGEKIEQLDRKGKVNNRFNAFIMEK
Sbjct  1    MLKQTLLYTGKAKSVYETDNADHLILVFRDDASAFNGEKIEQLDRKGKVNNRFNAFIMEK  60

Query  61   LAEAGIETHFEKLLTPNEVLVKKLNMIPVECVIRNYAAGSLCRRLGVEEGKQLTPPTFEL  120
            LAEAGIETHFEKLL+P EVLVKKL MIPVECVIRNYAAGSLCRRLGVEEGK+LTPPTFEL
Sbjct  61   LAEAGIETHFEKLLSPTEVLVKKLQMIPVECVIRNYAAGSLCRRLGVEEGKELTPPTFEL  120

Query  121  FFKDDALGDPMVNESQAIALGWATADQLEKMKELTYQVNDVLKALFDAGNMILVDFKLEF  180
            F+KDD LGDPMVNESQAIALGWATA+QLE+MK LTY+VNDVLKALF  GNMILVDFKLEF
Sbjct  121  FYKDDGLGDPMVNESQAIALGWATAEQLEQMKVLTYKVNDVLKALFAEGNMILVDFKLEF  180

Query  181  GVFHDRIVLGDEFSPDGCRLWDKDTKKKLDKDRFRQGLGGVVEAYEEVAARLGINLDDI  239
            GVFHDRIVLGDEFSPDGCRLWDKDTKKKLDKDRFRQGLGGVVEAYEEVAARLG++L DI
Sbjct  181  GVFHDRIVLGDEFSPDGCRLWDKDTKKKLDKDRFRQGLGGVVEAYEEVAARLGVDLSDI  239


>A5WHC5 Phosphoribosylaminoimidazole-succinocarboxamide synthase 
[Psychrobacter sp. (strain PRwf-1)]
Length=239

 Score = 384 bits (985),  Expect = 4e-140
 Identities = 184/235 (78%), Positives = 215/235 (91%), Gaps = 0/235 (0%)

Query  3    KQTLLYTGKAKSVYETDSADHLILVFRDDASAFNGEKIEQLDRKGKVNNRFNAFIMEKLA  62
            KQ LLY GKAKSVYET+++D+LIL FRDD SAFNGE+IEQL RKG+VNNRFNAFIM+KLA
Sbjct  5    KQDLLYKGKAKSVYETENSDYLILHFRDDTSAFNGERIEQLGRKGQVNNRFNAFIMQKLA  64

Query  63   EAGIETHFEKLLTPNEVLVKKLNMIPVECVIRNYAAGSLCRRLGVEEGKQLTPPTFELFF  122
            EAGIETHFEK L+ +EVLVK+L MIPVECV+RN+AAGSL RRLG+EEG+ LTPPT+ELFF
Sbjct  65   EAGIETHFEKQLSDDEVLVKRLEMIPVECVVRNFAAGSLVRRLGLEEGQPLTPPTYELFF  124

Query  123  KDDALGDPMVNESQAIALGWATADQLEKMKELTYQVNDVLKALFDAGNMILVDFKLEFGV  182
            KDDALGDPMVNES +++LGWAT +QL KMKELT++VNDVLK LFDAG ++LVDFKLEFGV
Sbjct  125  KDDALGDPMVNESLSVSLGWATPEQLAKMKELTFKVNDVLKELFDAGGLMLVDFKLEFGV  184

Query  183  FHDRIVLGDEFSPDGCRLWDKDTKKKLDKDRFRQGLGGVVEAYEEVAARLGINLD  237
            F DRIVLGDEFSPDGCR+WDK+TKKKLDKDRFRQ LG V+E+YEEVA R+G+ ++
Sbjct  185  FQDRIVLGDEFSPDGCRIWDKETKKKLDKDRFRQSLGDVIESYEEVAQRIGVPMN  239


>Q4FVD4 Phosphoribosylaminoimidazole-succinocarboxamide synthase 
[Psychrobacter arcticus (strain DSM 17307 / VKM B-2377 / 
273-4)]
Length=237

 Score = 372 bits (955),  Expect = 1e-135
 Identities = 182/236 (77%), Positives = 212/236 (90%), Gaps = 0/236 (0%)

Query  1    MLKQTLLYTGKAKSVYETDSADHLILVFRDDASAFNGEKIEQLDRKGKVNNRFNAFIMEK  60
            M KQ +LY GKAKSVYET+  D LIL FRDD SA +G++IEQL RKG VNNRFNAFIM+K
Sbjct  1    MQKQEMLYKGKAKSVYETEDNDLLILHFRDDTSALDGKRIEQLARKGVVNNRFNAFIMQK  60

Query  61   LAEAGIETHFEKLLTPNEVLVKKLNMIPVECVIRNYAAGSLCRRLGVEEGKQLTPPTFEL  120
            LA+AGIETHFEK L+ +EVLVK+L+MIPVECV+RN+AAGSL RRLG+EEG+ LTPPT+EL
Sbjct  61   LADAGIETHFEKQLSDDEVLVKRLDMIPVECVVRNFAAGSLVRRLGLEEGQALTPPTYEL  120

Query  121  FFKDDALGDPMVNESQAIALGWATADQLEKMKELTYQVNDVLKALFDAGNMILVDFKLEF  180
            F+KDDALGDPMVNES +I+LGWAT  QL KMKEL++QVN+VL ALFDAG++ILVDFKLEF
Sbjct  121  FYKDDALGDPMVNESISISLGWATDAQLAKMKELSHQVNEVLTALFDAGDLILVDFKLEF  180

Query  181  GVFHDRIVLGDEFSPDGCRLWDKDTKKKLDKDRFRQGLGGVVEAYEEVAARLGINL  236
            GVFHDRI+LGDEFSPDGCR+WDK TKKKLDKDRFRQ LG V+EAYEEVA+R+G+ L
Sbjct  181  GVFHDRIILGDEFSPDGCRIWDKATKKKLDKDRFRQSLGDVIEAYEEVASRIGVPL  236


>Q1QEF9 Phosphoribosylaminoimidazole-succinocarboxamide synthase 
[Psychrobacter cryohalolentis (strain ATCC BAA-1226 / DSM 
17306 / VKM B-2378 / K5)]
Length=237

 Score = 371 bits (952),  Expect = 4e-135
 Identities = 183/236 (78%), Positives = 211/236 (89%), Gaps = 0/236 (0%)

Query  1    MLKQTLLYTGKAKSVYETDSADHLILVFRDDASAFNGEKIEQLDRKGKVNNRFNAFIMEK  60
            M KQ LLY GKAKSVYET+  D LIL FRDD SA +G++IEQL RKG VNNRFNAFIM+K
Sbjct  1    MQKQELLYKGKAKSVYETEDNDLLILHFRDDTSALDGKRIEQLARKGVVNNRFNAFIMQK  60

Query  61   LAEAGIETHFEKLLTPNEVLVKKLNMIPVECVIRNYAAGSLCRRLGVEEGKQLTPPTFEL  120
            LA+AGIETHFEK L+ +EVLVK+L+MIPVECV+RN+AAGSL RRLG+EEG+ LTPPT+EL
Sbjct  61   LADAGIETHFEKQLSDDEVLVKRLDMIPVECVVRNFAAGSLVRRLGLEEGQALTPPTYEL  120

Query  121  FFKDDALGDPMVNESQAIALGWATADQLEKMKELTYQVNDVLKALFDAGNMILVDFKLEF  180
            F+KDDALGDPMVNES +I+LGWA   QL KMKEL++QVN+VL ALFDAG++ILVDFKLEF
Sbjct  121  FYKDDALGDPMVNESISISLGWANDAQLVKMKELSHQVNEVLTALFDAGDLILVDFKLEF  180

Query  181  GVFHDRIVLGDEFSPDGCRLWDKDTKKKLDKDRFRQGLGGVVEAYEEVAARLGINL  236
            GVFHDRIVLGDEFSPDGCR+WDK TKKKLDKDRFRQ LG V+EAYEEVA+R+G+ L
Sbjct  181  GVFHDRIVLGDEFSPDGCRIWDKATKKKLDKDRFRQSLGDVIEAYEEVASRIGVPL  236


>Q4ZW72 Phosphoribosylaminoimidazole-succinocarboxamide synthase 
[Pseudomonas syringae pv. syringae (strain B728a)]
Length=236

 Score = 353 bits (907),  Expect = 3e-128
 Identities = 172/236 (73%), Positives = 199/236 (84%), Gaps = 0/236 (0%)

Query  1    MLKQTLLYTGKAKSVYETDSADHLILVFRDDASAFNGEKIEQLDRKGKVNNRFNAFIMEK  60
            M K+  LY GKAKSVY+TD AD LIL+FR+D SAF+G++IEQLDRKG VNN+FNAFIM+K
Sbjct  1    MEKREELYRGKAKSVYKTDDADRLILLFRNDTSAFDGKRIEQLDRKGMVNNKFNAFIMQK  60

Query  61   LAEAGIETHFEKLLTPNEVLVKKLNMIPVECVIRNYAAGSLCRRLGVEEGKQLTPPTFEL  120
            L EAGI T F+KLL  NE LVKKL+MIPVECV+RNYAAGSL +RLG+EEG +L P TFEL
Sbjct  61   LEEAGIPTQFDKLLGDNECLVKKLDMIPVECVVRNYAAGSLVKRLGIEEGTRLNPYTFEL  120

Query  121  FFKDDALGDPMVNESQAIALGWATADQLEKMKELTYQVNDVLKALFDAGNMILVDFKLEF  180
            F KDDA GDP +NES  +A GW TA+QL +MKEL+ +VNDVL  LFD   ++LVDFKLEF
Sbjct  121  FLKDDAKGDPFINESHVVAFGWGTAEQLARMKELSIKVNDVLTKLFDDAGLLLVDFKLEF  180

Query  181  GVFHDRIVLGDEFSPDGCRLWDKDTKKKLDKDRFRQGLGGVVEAYEEVAARLGINL  236
            GVFH  IVLGDEFSPDGCRLWDKDT+KK+DKDRFRQGLG V+EAYEEVA RLG+ L
Sbjct  181  GVFHGEIVLGDEFSPDGCRLWDKDTRKKMDKDRFRQGLGDVIEAYEEVANRLGVPL  236


>Q87Y59 Phosphoribosylaminoimidazole-succinocarboxamide synthase 
[Pseudomonas syringae pv. tomato (strain ATCC BAA-871 / DC3000)]
Length=236

 Score = 352 bits (902),  Expect = 2e-127
 Identities = 171/236 (72%), Positives = 199/236 (84%), Gaps = 0/236 (0%)

Query  1    MLKQTLLYTGKAKSVYETDSADHLILVFRDDASAFNGEKIEQLDRKGKVNNRFNAFIMEK  60
            M K+  LY GKAKSVY+TD AD LIL+FR+D SAF+G++IEQLDRKG VNN+FNAFIM+K
Sbjct  1    MEKREELYRGKAKSVYKTDDADRLILLFRNDTSAFDGKRIEQLDRKGTVNNKFNAFIMQK  60

Query  61   LAEAGIETHFEKLLTPNEVLVKKLNMIPVECVIRNYAAGSLCRRLGVEEGKQLTPPTFEL  120
            L EAGI T F+KLL  NE LVKKL+MIPVECV+RNYAAGSL +RLG+EEG +L P TFEL
Sbjct  61   LEEAGIPTQFDKLLGDNECLVKKLDMIPVECVVRNYAAGSLVKRLGIEEGTKLNPYTFEL  120

Query  121  FFKDDALGDPMVNESQAIALGWATADQLEKMKELTYQVNDVLKALFDAGNMILVDFKLEF  180
            F KDDA GDP +NES  +A GW TA+QL +MKEL+ +VN+VL  LFD   ++LVDFKLEF
Sbjct  121  FLKDDAKGDPFINESHVVAFGWGTAEQLVRMKELSIKVNEVLTKLFDDAGLLLVDFKLEF  180

Query  181  GVFHDRIVLGDEFSPDGCRLWDKDTKKKLDKDRFRQGLGGVVEAYEEVAARLGINL  236
            GVFH  IVLGDEFSPDGCRLWDKDT+KK+DKDRFRQGLG V+EAYEEVA RLG+ L
Sbjct  181  GVFHGEIVLGDEFSPDGCRLWDKDTRKKMDKDRFRQGLGDVIEAYEEVANRLGVPL  236


>Q48LD2 Phosphoribosylaminoimidazole-succinocarboxamide synthase 
[Pseudomonas savastanoi pv. phaseolicola (strain 1448A / 
Race 6)]
Length=236

 Score = 351 bits (901),  Expect = 2e-127
 Identities = 170/236 (72%), Positives = 199/236 (84%), Gaps = 0/236 (0%)

Query  1    MLKQTLLYTGKAKSVYETDSADHLILVFRDDASAFNGEKIEQLDRKGKVNNRFNAFIMEK  60
            M K+  LY GKAKSVY+TD AD LIL+FR+D SAF+G++IEQLDRKG VNN+FNAFIM+K
Sbjct  1    MEKREELYRGKAKSVYKTDDADRLILLFRNDTSAFDGKRIEQLDRKGMVNNKFNAFIMQK  60

Query  61   LAEAGIETHFEKLLTPNEVLVKKLNMIPVECVIRNYAAGSLCRRLGVEEGKQLTPPTFEL  120
            L EAG+ T F+KLL  NE LVKKL+MIPVECV+RNYAAGSL +RLG+EEG +L P TFEL
Sbjct  61   LEEAGVPTQFDKLLGDNECLVKKLDMIPVECVVRNYAAGSLVKRLGIEEGTRLNPYTFEL  120

Query  121  FFKDDALGDPMVNESQAIALGWATADQLEKMKELTYQVNDVLKALFDAGNMILVDFKLEF  180
            F KDDA GDP +NES  +A GW TA+QL +MKEL+ +VN+VL  LFD   ++LVDFKLEF
Sbjct  121  FLKDDAKGDPFINESHVVAFGWGTAEQLVRMKELSIKVNEVLTKLFDDAGLLLVDFKLEF  180

Query  181  GVFHDRIVLGDEFSPDGCRLWDKDTKKKLDKDRFRQGLGGVVEAYEEVAARLGINL  236
            GVFH  IVLGDEFSPDGCRLWDKDT+KK+DKDRFRQGLG V+EAYEEVA RLG+ L
Sbjct  181  GVFHGEIVLGDEFSPDGCRLWDKDTRKKMDKDRFRQGLGDVIEAYEEVANRLGVPL  236


>Q3KGI9 Phosphoribosylaminoimidazole-succinocarboxamide synthase 
[Pseudomonas fluorescens (strain Pf0-1)]
Length=237

 Score = 348 bits (894),  Expect = 3e-126
 Identities = 173/237 (73%), Positives = 199/237 (84%), Gaps = 1/237 (0%)

Query  1    MLKQTLLYTGKAKSVYETDSADHLILVFRDDASAFNGEKIEQLDRKGKVNNRFNAFIMEK  60
            M K+  LY GKAKSVY+TD AD LIL+FR+D SAF+G++IEQLDRKG VNN+FNAFIM+K
Sbjct  1    MEKREELYRGKAKSVYKTDDADRLILLFRNDTSAFDGKRIEQLDRKGMVNNKFNAFIMQK  60

Query  61   LAEAGIETHFEKLLTPNEVLVKKLNMIPVECVIRNYAAGSLCRRLGVEEGKQLTPPTFEL  120
            L  AGI T F+KLL  NEVLVKKL+MIPVECV+RNYAAGSL +RLGVEEG +L P TFEL
Sbjct  61   LEAAGIPTQFDKLLADNEVLVKKLDMIPVECVVRNYAAGSLVKRLGVEEGMKLNPYTFEL  120

Query  121  FFKDDALGDPMVNESQAIALGWATADQLEKMKELTYQVNDVLKALFDAGNMILVDFKLEF  180
            F KDDA GDP +NES  +A GW TA+QL +MKEL+ +VN+VL  LFD   ++LVDFKLEF
Sbjct  121  FLKDDAKGDPFINESHVVAFGWGTAEQLARMKELSLKVNEVLSKLFDDAGLLLVDFKLEF  180

Query  181  GVFHD-RIVLGDEFSPDGCRLWDKDTKKKLDKDRFRQGLGGVVEAYEEVAARLGINL  236
            GVF D  IVLGDEFSPDGCRLWDKDTKKK+DKDRFRQGLG V+EAYEEVA RLG+ L
Sbjct  181  GVFSDGSIVLGDEFSPDGCRLWDKDTKKKMDKDRFRQGLGDVIEAYEEVANRLGVPL  237


>C3KED7 Phosphoribosylaminoimidazole-succinocarboxamide synthase 
[Pseudomonas fluorescens (strain SBW25)]
Length=237

 Score = 348 bits (894),  Expect = 3e-126
 Identities = 173/237 (73%), Positives = 199/237 (84%), Gaps = 1/237 (0%)

Query  1    MLKQTLLYTGKAKSVYETDSADHLILVFRDDASAFNGEKIEQLDRKGKVNNRFNAFIMEK  60
            M K+  LY GKAKSVY+TD A+ LIL+FR+D SAF+G++IEQLDRKG VNN+FNAFIM+K
Sbjct  1    MEKREELYRGKAKSVYKTDDANRLILLFRNDTSAFDGKRIEQLDRKGMVNNKFNAFIMQK  60

Query  61   LAEAGIETHFEKLLTPNEVLVKKLNMIPVECVIRNYAAGSLCRRLGVEEGKQLTPPTFEL  120
            L  AGI T F+KLL  NE LVKKL+MIPVECV+RNYAAGSL +RLGVEEG +L P TFEL
Sbjct  61   LEAAGIPTQFDKLLGDNECLVKKLDMIPVECVVRNYAAGSLVKRLGVEEGLKLNPYTFEL  120

Query  121  FFKDDALGDPMVNESQAIALGWATADQLEKMKELTYQVNDVLKALFDAGNMILVDFKLEF  180
            F KDDA GDP +NES  +A GW TA+QL +MKEL+ +VNDVL  LFD   ++LVDFKLEF
Sbjct  121  FLKDDAKGDPFINESHVVAFGWGTAEQLARMKELSLKVNDVLSKLFDDAGLLLVDFKLEF  180

Query  181  GVFHD-RIVLGDEFSPDGCRLWDKDTKKKLDKDRFRQGLGGVVEAYEEVAARLGINL  236
            GVFHD  IVLGDEFSPDGCRLWDKDTKKK+DKDRFRQGLG V+EAYEEVA RLG+ L
Sbjct  181  GVFHDGSIVLGDEFSPDGCRLWDKDTKKKMDKDRFRQGLGDVIEAYEEVANRLGVPL  237


>A6VX88 Phosphoribosylaminoimidazole-succinocarboxamide synthase 
[Marinomonas sp. (strain MWYL1)]
Length=238

 Score = 348 bits (892),  Expect = 6e-126
 Identities = 169/237 (71%), Positives = 196/237 (83%), Gaps = 0/237 (0%)

Query  1    MLKQTLLYTGKAKSVYETDSADHLILVFRDDASAFNGEKIEQLDRKGKVNNRFNAFIMEK  60
            M K+  LY GKAKSV+ TD  D ++LVFRDD SAF+G++IEQLDRKG VNN+FNAFIM K
Sbjct  1    MEKRQELYAGKAKSVFRTDDPDKMVLVFRDDTSAFDGKRIEQLDRKGMVNNKFNAFIMTK  60

Query  61   LAEAGIETHFEKLLTPNEVLVKKLNMIPVECVIRNYAAGSLCRRLGVEEGKQLTPPTFEL  120
            L EAGI THFEKLL+  E LVK L+MIPVECV+RN AAGSLCRRLGVEEG  LTPPTFEL
Sbjct  61   LQEAGIPTHFEKLLSDTESLVKCLDMIPVECVVRNVAAGSLCRRLGVEEGITLTPPTFEL  120

Query  121  FFKDDALGDPMVNESQAIALGWATADQLEKMKELTYQVNDVLKALFDAGNMILVDFKLEF  180
            F K+DALGDPM+NES   + GWA A  L K KELT++VNDVLKA+F  G MILVD+KLEF
Sbjct  121  FLKNDALGDPMINESHVESFGWAKASDLAKAKELTFKVNDVLKAIFAEGGMILVDYKLEF  180

Query  181  GVFHDRIVLGDEFSPDGCRLWDKDTKKKLDKDRFRQGLGGVVEAYEEVAARLGINLD  237
            G++   ++LGDEFSPDGCRLWD  TK+KLDKDRFRQGLGGV+EAYE+V  R+GI+ D
Sbjct  181  GLYKGEVLLGDEFSPDGCRLWDAKTKEKLDKDRFRQGLGGVIEAYEDVGRRIGIDFD  237


>P0A7D7 Phosphoribosylaminoimidazole-succinocarboxamide synthase 
[Escherichia coli (strain K12)]
Length=237

 Score = 315 bits (808),  Expect = 3e-113
 Identities = 153/237 (65%), Positives = 186/237 (78%), Gaps = 0/237 (0%)

Query  1    MLKQTLLYTGKAKSVYETDSADHLILVFRDDASAFNGEKIEQLDRKGKVNNRFNAFIMEK  60
            M KQ  LY GKAK+VY T++ D L+L FR+D SA +G +IEQ DRKG VNN+FN FIM K
Sbjct  1    MQKQAELYRGKAKTVYSTENPDLLVLEFRNDTSAGDGARIEQFDRKGMVNNKFNYFIMSK  60

Query  61   LAEAGIETHFEKLLTPNEVLVKKLNMIPVECVIRNYAAGSLCRRLGVEEGKQLTPPTFEL  120
            LAEAGI T  E+LL+  E LVKKL+M+PVECV+RN AAGSL +RLG+EEG +L PP F+L
Sbjct  61   LAEAGIPTQMERLLSDTECLVKKLDMVPVECVVRNRAAGSLVKRLGIEEGIELNPPLFDL  120

Query  121  FFKDDALGDPMVNESQAIALGWATADQLEKMKELTYQVNDVLKALFDAGNMILVDFKLEF  180
            F K+DA+ DPMVNES     GW + + L +MKELTY+ NDVLK LFD   +ILVDFKLEF
Sbjct  121  FLKNDAMHDPMVNESYCETFGWVSKENLARMKELTYKANDVLKKLFDDAGLILVDFKLEF  180

Query  181  GVFHDRIVLGDEFSPDGCRLWDKDTKKKLDKDRFRQGLGGVVEAYEEVAARLGINLD  237
            G++   +VLGDEFSPDG RLWDK+T +K+DKDRFRQ LGG++EAYE VA RLG+ LD
Sbjct  181  GLYKGEVVLGDEFSPDGSRLWDKETLEKMDKDRFRQSLGGLIEAYEAVARRLGVQLD  237


>P12046 Phosphoribosylaminoimidazole-succinocarboxamide synthase 
[Bacillus subtilis (strain 168)]
Length=241

 Score = 229 bits (585),  Expect = 3e-79
 Identities = 109/234 (47%), Positives = 163/234 (70%), Gaps = 1/234 (0%)

Query  1    MLKQTLLYTGKAKSVYETDSADHLILVFRDDASAFNGEKIEQLDRKGKVNNRFNAFIMEK  60
            ++K  LLY GKAK +Y+TD  + L +V++D A+AFNGEK  ++  KG++NN  ++ I + 
Sbjct  3    IVKNELLYEGKAKKIYKTDDENTLYVVYKDSATAFNGEKKAEISGKGRLNNEISSLIFKH  62

Query  61   LAEAGIETHFEKLLTPNEVLVKKLNMIPVECVIRNYAAGSLCRRLGVEEGKQLTPPTFEL  120
            L   GI  HF + ++  E L+KK+ ++P+E V+RN  AGS+ +RLG+ EG +L  P  E 
Sbjct  63   LHAKGINNHFIERISETEQLIKKVTIVPLEVVVRNVVAGSMSKRLGIPEGTELEQPIIEF  122

Query  121  FFKDDALGDPMVNESQAIALGWATADQLEKMKELTYQVNDVLKALFDAGNMILVDFKLEF  180
            ++KDDALGDP++ E     L  AT +Q+E +K +T  VN+ L+++FD  ++ L+DFKLEF
Sbjct  123  YYKDDALGDPLITEDHIWLLKAATPEQVETIKSITTIVNEELQSIFDDCHVRLIDFKLEF  182

Query  181  GV-FHDRIVLGDEFSPDGCRLWDKDTKKKLDKDRFRQGLGGVVEAYEEVAARLG  233
            G+    +++L DE SPD CRLWDK+T +KLDKD FR+ LG + +AYEE+  RLG
Sbjct  183  GLDAEGQVLLADEISPDTCRLWDKETNEKLDKDLFRRNLGSLTDAYEEIFNRLG  236


>Q07296 Phosphoribosylaminoimidazole-succinocarboxamide synthase 
[Streptococcus pneumoniae serotype 4 (strain ATCC BAA-334 
/ TIGR4)]
Length=235

 Score = 204 bits (520),  Expect = 2e-69
 Identities = 106/232 (46%), Positives = 151/232 (65%), Gaps = 2/232 (1%)

Query  2    LKQTLLYTGKAKSVYETDSADHLILVFRDDASAFNGEKIEQLDRKGKVNNRFNAFIMEKL  61
            + + L+Y+GKAK +Y T+  + +I  ++D A+AFNG K EQ+  KG +NN+ ++FI EKL
Sbjct  1    MSKQLIYSGKAKDIYTTEDENLIISTYKDQATAFNGVKKEQIAGKGVLNNQISSFIFEKL  60

Query  62   AEAGIETHFEKLLTPNEVLVKKLNMIPVECVIRNYAAGSLCRRLGVEEGKQLTPPTFELF  121
              AG+ THF + L+  E L KK+ +IP+E V+RNY AGS  +R GV+EG  L  P  E +
Sbjct  61   NVAGVATHFVEKLSDTEQLNKKVKIIPLEVVLRNYTAGSFSKRFGVDEGIALETPIVEFY  120

Query  122  FKDDALGDPMVNESQAIALGWATADQLEKMKELTYQVNDVLKALFDAGNMILVDFKLEFG  181
            +K+D L DP +N+     L  A   Q+  +KE T ++N++LK  F    + L+DFKLEFG
Sbjct  121  YKNDDLDDPFINDEHVKFLQIAGDQQIAYLKEETRRINELLKVWFAEIGLKLIDFKLEFG  180

Query  182  VFHD-RIVLGDEFSPDGCRLWDKDTKKKLDKDRFRQGLGGVVEAYEEVAARL  232
               D +I+L DEFSPD CRLWD D    +DKD FR+GLG + + YE V  +L
Sbjct  181  FDKDGKIILADEFSPDNCRLWDAD-GNHMDKDVFRRGLGELTDVYEIVWEKL  231


>O68830 Phosphoribosylaminoimidazole-succinocarboxamide synthase 
[Lactococcus lactis subsp. lactis (strain IL1403)]
Length=236

 Score = 196 bits (498),  Expect = 3e-66
 Identities = 104/229 (45%), Positives = 148/229 (65%), Gaps = 2/229 (1%)

Query  1    MLKQTLLYTGKAKSVYETDSADHLILVFRDDASAFNGEKIEQLDRKGKVNNRFNAFIMEK  60
            M K+ LLY GKAK +Y TD ++ L + + D A+A NG + EQ+  KG +NN+  + I EK
Sbjct  1    MEKEKLLYEGKAKKLYFTDDSEVLWVEYCDQATALNGARKEQITGKGALNNQITSLIFEK  60

Query  61   LAEAGIETHFEKLLTPNEVLVKKLNMIPVECVIRNYAAGSLCRRLGVEEGKQLTPPTFEL  120
            L   G+ETHF + L+  E L +K+++IP+E V+RN  AGS  +R G+EEG  L  P  E 
Sbjct  61   LNAEGLETHFIEKLSKTEQLNRKVSIIPLEVVLRNVVAGSFAKRFGLEEGIVLQEPIVEF  120

Query  121  FFKDDALGDPMVNESQAIALGWATADQLEKMKELTYQVNDVLKALFDAGNMILVDFKLEF  180
            ++KDDAL DP +N+     L  AT  ++E +K  T ++N++LK ++    + LVDFKLEF
Sbjct  121  YYKDDALDDPFINDEHVRFLNIATYSEIEFLKSETRKINEILKKIWAEIGLTLVDFKLEF  180

Query  181  GVFHD-RIVLGDEFSPDGCRLWDKDTKKKLDKDRFRQGLGGVVEAYEEV  228
            G   D RI+L DE SPD  RLWD +  + +DKD FR+ +G +VE Y EV
Sbjct  181  GRLADGRIILADEISPDTSRLWDAN-GQHMDKDVFRRNIGDLVETYTEV  228


>Q9R7D5 Phosphoribosylaminoimidazole-succinocarboxamide synthase 
[Lactococcus lactis subsp. cremoris]
Length=236

 Score = 195 bits (496),  Expect = 7e-66
 Identities = 104/229 (45%), Positives = 147/229 (64%), Gaps = 2/229 (1%)

Query  1    MLKQTLLYTGKAKSVYETDSADHLILVFRDDASAFNGEKIEQLDRKGKVNNRFNAFIMEK  60
            M K+TLLY GKAK +Y TD ++ L + + D A+A NG + EQ+  KG +NN+  + I EK
Sbjct  1    MEKETLLYEGKAKKLYFTDDSNVLWVEYCDQATALNGARKEQITGKGALNNQITSLIFEK  60

Query  61   LAEAGIETHFEKLLTPNEVLVKKLNMIPVECVIRNYAAGSLCRRLGVEEGKQLTPPTFEL  120
            L   G+ETHF K L+  E L KK+++IP+E V+RN  AGS  +R G+EEG  L  P  E 
Sbjct  61   LNAEGLETHFIKKLSKTEQLNKKVSIIPLEVVLRNVVAGSFAKRFGLEEGIVLEEPIVEF  120

Query  121  FFKDDALGDPMVNESQAIALGWATADQLEKMKELTYQVNDVLKALFDAGNMILVDFKLEF  180
            ++KDDAL DP +N+     L  A+  ++E +K+ T ++N +LK ++    + LVDFKLEF
Sbjct  121  YYKDDALDDPFINDEHVKFLNIASDSEIEFLKKETRKINKILKKIWTEIGLTLVDFKLEF  180

Query  181  GVFHD-RIVLGDEFSPDGCRLWDKDTKKKLDKDRFRQGLGGVVEAYEEV  228
            G   D  I+L DE SPD  RLWD    + +DKD FR+ +G ++E Y EV
Sbjct  181  GRLADGSIILADEISPDTSRLWDA-KGQHMDKDVFRRNIGDLIETYTEV  228


>P51583 Phosphoribosylaminoimidazole carboxylase / Phosphoribosylaminoimidazole 
succinocarboxamide synthetase [Rattus norvegicus]
Length=425

 Score = 124 bits (311),  Expect = 1e-36
 Identities = 89/248 (36%), Positives = 126/248 (51%), Gaps = 18/248 (7%)

Query  7    LYTGKAKSVYET-DSADHLILVFRDDASAFNGEKIEQLDRKGKVNNRFNAFIMEKLAEAG  65
            LY GK K VYE  DS   ++L  +D  +A N  +   L+ K  ++N+  + I + L EAG
Sbjct  13   LYEGKTKEVYELLDSPGRVLLQSKDQITAGNAARKNHLEGKAAISNKITSCIFQLLQEAG  72

Query  66   IETHFEKLLTPNEVLVKKLNMIPVECVIRNYAAGS-LCRRLGVEEGKQLTPPTFELFFKD  124
            I+T F K       +  +  MIP+E V R  A GS L R  GV+EG +  PP  E+FFKD
Sbjct  73   IKTAFTKKCGETAFIAPQCEMIPIEWVCRRIATGSFLKRNPGVKEGYRFYPPKVEMFFKD  132

Query  125  DALGDPMVNESQAIALGWATA------DQLEKMKELTYQVNDVLKALFDAGNMILVDFKL  178
            DA  DP  +E Q IA  +  A       +++ M   T  + ++L+  +   N  LVD K+
Sbjct  133  DANNDPQWSEEQLIAAKFCFAGLVIGQTEVDIMSHATQAIFEILEKSWLPQNCTLVDMKI  192

Query  179  EFG--VFHDRIVLGDEFSPDGCRLWDK-DTKKKLDKDRFR-------QGLGGVVEAYEEV  228
            EFG  V    IVL D    D  RLW   D  ++ DK  +R       +GL  V + +E V
Sbjct  193  EFGVDVTTKEIVLADVIDNDSWRLWPSGDRSQQKDKQSYRDLKEVTPEGLQMVKKNFEWV  252

Query  229  AARLGINL  236
            A R+ + L
Sbjct  253  ADRVELLL  260


>P22234 Phosphoribosylaminoimidazole carboxylase / Phosphoribosylaminoimidazole 
succinocarboxamide synthetase [Homo sapiens]
Length=425

 Score = 124 bits (310),  Expect = 2e-36
 Identities = 89/248 (36%), Positives = 126/248 (51%), Gaps = 18/248 (7%)

Query  7    LYTGKAKSVYET-DSADHLILVFRDDASAFNGEKIEQLDRKGKVNNRFNAFIMEKLAEAG  65
            LY GK K VYE  DS   ++L  +D  +A N  +   L+ K  ++N+  + I + L EAG
Sbjct  13   LYEGKTKEVYELLDSPGKVLLQSKDQITAGNAARKNHLEGKAAISNKITSCIFQLLQEAG  72

Query  66   IETHFEKLLTPNEVLVKKLNMIPVECVIRNYAAGS-LCRRLGVEEGKQLTPPTFELFFKD  124
            I+T F +       +  +  MIP+E V R  A GS L R  GV+EG +  PP  ELFFKD
Sbjct  73   IKTAFTRKCGETAFIAPQCEMIPIEWVCRRIATGSFLKRNPGVKEGYKFYPPKVELFFKD  132

Query  125  DALGDPMVNESQAIALGWATA------DQLEKMKELTYQVNDVLKALFDAGNMILVDFKL  178
            DA  DP  +E Q IA  +  A       +++ M   T  + ++L+  +   N  LVD K+
Sbjct  133  DANNDPQWSEEQLIAAKFCFAGLLIGQTEVDIMSHATQAIFEILEKSWLPQNCTLVDMKI  192

Query  179  EFG--VFHDRIVLGDEFSPDGCRLWDK-DTKKKLDKDRFR-------QGLGGVVEAYEEV  228
            EFG  V    IVL D    D  RLW   D  ++ DK  +R       +GL  V + +E V
Sbjct  193  EFGVDVTTKEIVLADVIDNDSWRLWPSGDRSQQKDKQSYRDLKEVTPEGLQMVKKNFEWV  252

Query  229  AARLGINL  236
            A R+ + L
Sbjct  253  AERVELLL  260


>Q9I7S8 Phosphoribosylaminoimidazole-succinocarboxamide synthase 
/ Phosphoribosylaminoimidazole carboxylase [Drosophila melanogaster]
Length=429

 Score = 115 bits (289),  Expect = 2e-33
 Identities = 76/220 (35%), Positives = 113/220 (51%), Gaps = 10/220 (5%)

Query  6    LLYTGKAKSVYETDSADHL-ILVFRDDASAFNGEKIEQLDRKGKVNNRFNAFIMEKLAEA  64
            ++  GK K VY+      L +L+ +D  +A +G K   L  K +++N  N  +   L EA
Sbjct  17   VIIEGKTKQVYDLPEQPGLCLLLSKDRITAGDGVKAHDLAGKAEISNTTNGQVFRLLNEA  76

Query  65   GIETHFEKLLTPNEVLVKKLNMIPVECVIRNYAAGS-LCRRLGVEEGKQLTPPTFELFFK  123
            GI T + K       + +K  MIP+E V R  A GS L R +GV EG + +PP  E FFK
Sbjct  77   GIRTAYVKQCGAKAFIARKCQMIPIEWVTRRLATGSFLKRNVGVPEGYRFSPPKQETFFK  136

Query  124  DDALGDPMVNESQAIALGWAT------ADQLEKMKELTYQVNDVLKALFDAGNMILVDFK  177
            DDA  DP  +E Q ++  +         D+++ M+  T  V ++L+  +   N  L+D K
Sbjct  137  DDANHDPQWSEEQIVSAKFELNGLVIGQDEVDIMRRTTLLVFEILERAWQTKNCALIDMK  196

Query  178  LEFGVFHD-RIVLGDEFSPDGCRLWDK-DTKKKLDKDRFR  215
            +EFG+  D  IVL D    D  RLW   D +  +DK  +R
Sbjct  197  VEFGICDDGNIVLADIIDSDSWRLWPAGDKRLMVDKQVYR  236


>P38024 Phosphoribosylaminoimidazole-succinocarboxamide synthase 
/ Phosphoribosylaminoimidazole carboxylase [Gallus gallus]
Length=426

 Score = 109 bits (273),  Expect = 4e-31
 Identities = 79/245 (32%), Positives = 121/245 (49%), Gaps = 18/245 (7%)

Query  10   GKAKSVYETDSADHLILV-FRDDASAFNGEKIEQLDRKGKVNNRFNAFIMEKLAEAGIET  68
            GK K VYE       +L+  +D  +A N  + ++++ K  ++N   + + + L EAGI+T
Sbjct  17   GKTKEVYELPDIPGCVLMQSKDQITAGNAARKDRMEGKAAISNTTTSCVFQLLQEAGIKT  76

Query  69   HFEKLLTPNEVLVKKLNMIPVECVIRNYAAGS-LCRRLGVEEGKQLTPPTFELFFKDDAL  127
             F +  +    +     MIP+E V R  A GS L R  GV+EG +  PP  E+F+KDDA 
Sbjct  77   AFVRKQSDTAFIAAHCEMIPIEWVCRRIATGSFLKRNPGVKEGYKFYPPKIEMFYKDDAN  136

Query  128  GDPMVNESQAIALGWATA------DQLEKMKELTYQVNDVLKALFDAGNMILVDFKLEFG  181
             DP  +E Q I   ++ A       +++ M   T  + ++L+  +   N  LVD K+EFG
Sbjct  137  NDPQWSEEQLIEAKFSFAGLTIGKTEVDIMARSTQAIFEILEKSWQPQNCTLVDLKIEFG  196

Query  182  V--FHDRIVLGDEFSPDGCRLWDK-DTKKKLDKDRFR-------QGLGGVVEAYEEVAAR  231
            V      IVL D    D  RLW   D  ++ DK  +R       + L  V   +E VA R
Sbjct  197  VNILTKEIVLADVIDNDSWRLWPSGDRSQQKDKQSYRDLKEVTPEALQMVKRNFEWVAER  256

Query  232  LGINL  236
            + + L
Sbjct  257  VELLL  261


>P9WHN1 Phosphoribosylaminoimidazole-succinocarboxamide synthase 
[Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv)]
Length=297

 Score = 66.6 bits (161),  Expect = 3e-16
 Identities = 69/250 (28%), Positives = 105/250 (42%), Gaps = 29/250 (12%)

Query  9    TGKAKSVYETDSADHLILVFRDDASAFNGEKIEQLDRKGKVNNRFNAFIMEKL-AEAGIE  67
            +GK + +Y  D  +HL+LV  D  SA++      +  KG+V    +AF    + A   + 
Sbjct  13   SGKVREIYRVDD-EHLLLVASDRISAYDYVLDSTIPDKGRVLTAMSAFFFGLVDAPNHLA  71

Query  68   THFEKLLTPNEVL-----VKKLNMIPVECVIRNYAAGS-------------LCRRLGVEE  109
               +    P+EVL     V++L M+PVECV R Y  GS             +    G+ E
Sbjct  72   GPPDDPRIPDEVLGRALVVRRLEMLPVECVARGYLTGSGLLDYQATGKVCGIALPPGLVE  131

Query  110  GKQLTPPTFELFFKDDALGDPMVNESQAIALGWATADQLEKMKELTYQVNDVLKALFDAG  169
              +   P F    K  ALGD   N S    +    A +  ++++ T Q            
Sbjct  132  ASRFATPLFTPATK-AALGDHDENISFDRVVEMVGALRANQLRDRTLQTYVQAADHALTR  190

Query  170  NMILVDFKLEFGV-FHDRIVLGDE-FSPDGCRLWDKD------TKKKLDKDRFRQGLGGV  221
             +I+ D K EFG+  H  ++L DE F+PD  R W  D       +   DK   R  L G 
Sbjct  191  GIIIADTKFEFGIDRHGNLLLADEIFTPDSSRYWPADDYRAGVVQTSFDKQFVRSWLTGS  250

Query  222  VEAYEEVAAR  231
               ++  + R
Sbjct  251  ESGWDRGSDR  260



Lambda      K        H        a         alpha
   0.322    0.140    0.409    0.792     4.96 

Gapped
Lambda      K        H        a         alpha    sigma
   0.267   0.0410    0.140     1.90     42.6     43.6 

Effective search space used: 1087176


  Database: 30a6676c21fdff631589a62bc2f052c8.SwissProt.fasta
    Posted date:  May 20, 2024  4:24 AM
  Number of letters in database: 6,754
  Number of sequences in database:  25



Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Neighboring words threshold: 11
Window for multiple hits: 40