BLASTP 2.12.0+
Reference: Stephen F. Altschul, Thomas L. Madden, Alejandro A.
Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J.
Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of
protein database search programs", Nucleic Acids Res. 25:3389-3402.
Reference for composition-based statistics: Alejandro A. Schaffer,
L. Aravind, Thomas L. Madden, Sergei Shavirin, John L. Spouge, Yuri
I. Wolf, Eugene V. Koonin, and Stephen F. Altschul (2001),
"Improving the accuracy of PSI-BLAST protein database searches with
composition-based statistics and other refinements", Nucleic Acids
Res. 29:2994-3005.
Database: bbad014335374fd95329a407b56799ea.SwissProt.fasta
11 sequences; 4,534 total letters
Query= ACIAD3577
Length=129
Score E
Sequences producing significant alignments: (Bits) Value
A5PKH3 Fumarylacetoacetase [Bos taurus] 93.2 8e-27
P16930 Fumarylacetoacetase [Homo sapiens] 92.4 2e-26
P35505 Fumarylacetoacetase [Mus musculus] 88.6 4e-25
P25093 Fumarylacetoacetase [Rattus norvegicus] 86.3 3e-24
Q6H7M1 Fumarylacetoacetase [Oryza sativa subsp. japonica] 85.5 5e-24
Q1ZXQ1 Fumarylacetoacetase [Dictyostelium discoideum] 85.1 7e-24
Q8RW90 Fumarylacetoacetase [Arabidopsis thaliana] 84.3 1e-23
Q94272 Fumarylacetoacetase [Caenorhabditis elegans] 83.6 2e-23
Q4WHT8 Fumarylacetoacetase fahA [Aspergillus fumigatus (strain AT... 81.6 1e-22
Q00770 Fumarylacetoacetase [Emericella nidulans (strain FGSC A4 /... 79.3 8e-22
O06724 Uncharacterized protein YisK [Bacillus subtilis (strain 168)] 42.4 7e-09
>A5PKH3 Fumarylacetoacetase [Bos taurus]
Length=419
Score = 93.2 bits (230), Expect = 8e-27
Identities = 42/74 (57%), Positives = 55/74 (74%), Gaps = 0/74 (0%)
Query 45 VMVSGTDIIRPSGQIKLPDQERPVFSACHKLDFELETGFIIGKSSQVGQPIPIESAWDHI 104
V+VSGT I RP GQ++ D + PV+ AC LDFELE F +G +++G+PIPI A +HI
Sbjct 166 VVVSGTPIRRPLGQMRPDDSKPPVYGACKLLDFELEMAFFVGPGNKLGEPIPISKAHEHI 225
Query 105 FGIVLFNDWSARDL 118
FG+VL NDWSARD+
Sbjct 226 FGMVLMNDWSARDI 239
Score = 52.8 bits (125), Expect = 2e-12
Identities = 22/40 (55%), Positives = 31/40 (78%), Gaps = 0/40 (0%)
Query 7 SFIDVSPQSDFPIQNLPYGIFSTTVHGKRRVGVALGDWVM 46
SF+ V+ SDFPI NLPYG+FST + + R+GVA+GD ++
Sbjct 2 SFVPVAEDSDFPIHNLPYGVFSTRGNPRPRIGVAIGDQIL 41
>P16930 Fumarylacetoacetase [Homo sapiens]
Length=419
Score = 92.4 bits (228), Expect = 2e-26
Identities = 42/74 (57%), Positives = 54/74 (73%), Gaps = 0/74 (0%)
Query 45 VMVSGTDIIRPSGQIKLPDQERPVFSACHKLDFELETGFIIGKSSQVGQPIPIESAWDHI 104
V+VSGT I RP GQ+K D + PV+ AC LD ELE F +G +++G+PIPI A +HI
Sbjct 166 VVVSGTPIRRPMGQMKPDDSKPPVYGACKLLDMELEMAFFVGPGNRLGEPIPISKAHEHI 225
Query 105 FGIVLFNDWSARDL 118
FG+VL NDWSARD+
Sbjct 226 FGMVLMNDWSARDI 239
Score = 52.4 bits (124), Expect = 2e-12
Identities = 23/40 (58%), Positives = 30/40 (75%), Gaps = 0/40 (0%)
Query 7 SFIDVSPQSDFPIQNLPYGIFSTTVHGKRRVGVALGDWVM 46
SFI V+ SDFPI NLPYG+FST + R+GVA+GD ++
Sbjct 2 SFIPVAEDSDFPIHNLPYGVFSTRGDPRPRIGVAIGDQIL 41
Score = 16.2 bits (30), Expect = 5.7
Identities = 9/36 (25%), Positives = 13/36 (36%), Gaps = 2/36 (6%)
Query 38 GVALGDWVMVSGTDIIRPSGQIKLPDQERPVFSACH 73
G + WV+ D + P RP+ CH
Sbjct 256 GTTVSPWVVPM--DALMPFAVPNPKQDPRPLPYLCH 289
>P35505 Fumarylacetoacetase [Mus musculus]
Length=419
Score = 88.6 bits (218), Expect = 4e-25
Identities = 39/74 (53%), Positives = 53/74 (72%), Gaps = 0/74 (0%)
Query 45 VMVSGTDIIRPSGQIKLPDQERPVFSACHKLDFELETGFIIGKSSQVGQPIPIESAWDHI 104
++VSGT I RP GQ++ + + PV+ AC LD ELE F +G ++ G+PIPI A +HI
Sbjct 166 IVVSGTPIRRPMGQMRPDNSKPPVYGACRLLDMELEMAFFVGPGNRFGEPIPISKAHEHI 225
Query 105 FGIVLFNDWSARDL 118
FG+VL NDWSARD+
Sbjct 226 FGMVLMNDWSARDI 239
Score = 56.6 bits (135), Expect = 8e-14
Identities = 25/40 (63%), Positives = 32/40 (80%), Gaps = 0/40 (0%)
Query 7 SFIDVSPQSDFPIQNLPYGIFSTTVHGKRRVGVALGDWVM 46
SFI V+ SDFPIQNLPYG+FST + K R+GVA+GD ++
Sbjct 2 SFIPVAEDSDFPIQNLPYGVFSTQSNPKPRIGVAIGDQIL 41
>P25093 Fumarylacetoacetase [Rattus norvegicus]
Length=419
Score = 86.3 bits (212), Expect = 3e-24
Identities = 39/74 (53%), Positives = 53/74 (72%), Gaps = 0/74 (0%)
Query 45 VMVSGTDIIRPSGQIKLPDQERPVFSACHKLDFELETGFIIGKSSQVGQPIPIESAWDHI 104
V+VSGT I RP GQ++ + + PV+ A +LD ELE F +G ++ G+PIPI A +HI
Sbjct 166 VVVSGTPIRRPMGQMRPDNSKPPVYGASKRLDMELEMAFFVGPGNRFGEPIPISKAQEHI 225
Query 105 FGIVLFNDWSARDL 118
FG+VL NDWSARD+
Sbjct 226 FGMVLMNDWSARDI 239
Score = 56.6 bits (135), Expect = 8e-14
Identities = 25/40 (63%), Positives = 32/40 (80%), Gaps = 0/40 (0%)
Query 7 SFIDVSPQSDFPIQNLPYGIFSTTVHGKRRVGVALGDWVM 46
SFI V+ SDFPIQNLPYG+FST + K R+GVA+GD ++
Sbjct 2 SFIPVAEDSDFPIQNLPYGVFSTQSNPKPRIGVAIGDQIL 41
>Q6H7M1 Fumarylacetoacetase [Oryza sativa subsp. japonica]
Length=429
Score = 85.5 bits (210), Expect = 5e-24
Identities = 40/74 (54%), Positives = 51/74 (69%), Gaps = 0/74 (0%)
Query 45 VMVSGTDIIRPSGQIKLPDQERPVFSACHKLDFELETGFIIGKSSQVGQPIPIESAWDHI 104
V+VSGTDIIRP GQ RP F KLDFELE I+G +++G+PI I A +HI
Sbjct 179 VIVSGTDIIRPKGQGHPTGDSRPYFGPSKKLDFELEMAAIVGPGNELGKPIDINDAEEHI 238
Query 105 FGIVLFNDWSARDL 118
FG+++ NDWSARD+
Sbjct 239 FGLMIMNDWSARDI 252
Score = 40.4 bits (93), Expect = 3e-08
Identities = 20/45 (44%), Positives = 29/45 (64%), Gaps = 3/45 (7%)
Query 5 LSSFIDVSPQSDFPIQNLPYGIF---STTVHGKRRVGVALGDWVM 46
L SF++V+P S FPIQNLP+G+F + R VA+GD+ +
Sbjct 9 LRSFVEVAPGSHFPIQNLPFGVFRRRGSPEPEPPRPAVAIGDFAL 53
>Q1ZXQ1 Fumarylacetoacetase [Dictyostelium discoideum]
Length=427
Score = 85.1 bits (209), Expect = 7e-24
Identities = 43/76 (57%), Positives = 57/76 (75%), Gaps = 2/76 (3%)
Query 45 VMVSGTDIIRPSGQIKLPDQER-PVFSACHKLDFELETGFIIG-KSSQVGQPIPIESAWD 102
++VSGT + RP GQ K + + P F+ C LDFELE G +IG +S+++G+PI IESA D
Sbjct 170 IVVSGTPLKRPWGQTKSDEPDSLPTFNPCRLLDFELEMGALIGGESTKLGEPISIESAKD 229
Query 103 HIFGIVLFNDWSARDL 118
HIFG+VL NDWSARD+
Sbjct 230 HIFGLVLLNDWSARDI 245
Score = 57.4 bits (137), Expect = 4e-14
Identities = 25/41 (61%), Positives = 33/41 (80%), Gaps = 0/41 (0%)
Query 5 LSSFIDVSPQSDFPIQNLPYGIFSTTVHGKRRVGVALGDWV 45
L SFI+VS S FPIQNLPYG+F T++ + R+GVA+GD+V
Sbjct 4 LKSFIEVSEDSHFPIQNLPYGVFKPTLNDQARIGVAIGDFV 44
>Q8RW90 Fumarylacetoacetase [Arabidopsis thaliana]
Length=421
Score = 84.3 bits (207), Expect = 1e-23
Identities = 37/74 (50%), Positives = 51/74 (69%), Gaps = 0/74 (0%)
Query 45 VMVSGTDIIRPSGQIKLPDQERPVFSACHKLDFELETGFIIGKSSQVGQPIPIESAWDHI 104
+++SGTDIIRP GQ P F KLDFELE ++G +++G+PI + +A DHI
Sbjct 171 IVISGTDIIRPRGQGHPQGNSEPYFGPSKKLDFELEMAAVVGPGNELGKPIDVNNAADHI 230
Query 105 FGIVLFNDWSARDL 118
FG++L NDWSARD+
Sbjct 231 FGLLLMNDWSARDI 244
Score = 48.5 bits (114), Expect = 5e-11
Identities = 23/42 (55%), Positives = 27/42 (64%), Gaps = 0/42 (0%)
Query 5 LSSFIDVSPQSDFPIQNLPYGIFSTTVHGKRRVGVALGDWVM 46
L SFIDV S FPIQNLPYG+F + R VA+GD V+
Sbjct 4 LKSFIDVGSDSHFPIQNLPYGVFKPESNSTPRPAVAIGDLVL 45
>Q94272 Fumarylacetoacetase [Caenorhabditis elegans]
Length=418
Score = 83.6 bits (205), Expect = 2e-23
Identities = 40/75 (53%), Positives = 51/75 (68%), Gaps = 1/75 (1%)
Query 45 VMVSGTDIIRPSGQIKLPDQERPVFSACHKLDFELETGFII-GKSSQVGQPIPIESAWDH 103
++VSGTD+ RP GQ K PD E P F +DFELE F + G +++G +PIE A D
Sbjct 167 IVVSGTDLKRPVGQTKAPDAEVPSFGPSKLMDFELEMAFFVGGPENELGTRVPIEKAEDR 226
Query 104 IFGIVLFNDWSARDL 118
IFG+VL NDWSARD+
Sbjct 227 IFGVVLMNDWSARDI 241
Score = 56.2 bits (134), Expect = 1e-13
Identities = 23/42 (55%), Positives = 30/42 (71%), Gaps = 0/42 (0%)
Query 5 LSSFIDVSPQSDFPIQNLPYGIFSTTVHGKRRVGVALGDWVM 46
+ SF+ V SDFPIQNLPYG+FST R +GVA+GD ++
Sbjct 1 MKSFVSVPQNSDFPIQNLPYGVFSTKADSSRHIGVAIGDQIL 42
>Q4WHT8 Fumarylacetoacetase fahA [Aspergillus fumigatus (strain
ATCC MYA-4609 / CBS 101355 / FGSC A1100 / Af293)]
Length=431
Score = 81.6 bits (200), Expect = 1e-22
Identities = 39/77 (51%), Positives = 53/77 (69%), Gaps = 3/77 (4%)
Query 45 VMVSGTDIIRPSGQI---KLPDQERPVFSACHKLDFELETGFIIGKSSQVGQPIPIESAW 101
V+ SGT I RP+GQI + + P FS C +LD ELE + KS+++G+P+ I+ A
Sbjct 173 VVTSGTPIRRPNGQILANPAANPKVPTFSPCKRLDIELELAAFVSKSNELGKPVSIDEAE 232
Query 102 DHIFGIVLFNDWSARDL 118
DHIFG+VL NDWSARD+
Sbjct 233 DHIFGVVLMNDWSARDI 249
Score = 30.0 bits (66), Expect = 1e-04
Identities = 12/42 (29%), Positives = 24/42 (57%), Gaps = 0/42 (0%)
Query 5 LSSFIDVSPQSDFPIQNLPYGIFSTTVHGKRRVGVALGDWVM 46
++S++ + S F + N+P+GI S+ VA+GD+ +
Sbjct 1 MASWLQIPKNSPFSLANIPFGIISSAKITSPVAAVAVGDYAL 42
>Q00770 Fumarylacetoacetase [Emericella nidulans (strain FGSC
A4 / ATCC 38163 / CBS 112.46 / NRRL 194 / M139)]
Length=431
Score = 79.3 bits (194), Expect = 8e-22
Identities = 38/77 (49%), Positives = 49/77 (64%), Gaps = 3/77 (4%)
Query 45 VMVSGTDIIRPSGQI---KLPDQERPVFSACHKLDFELETGFIIGKSSQVGQPIPIESAW 101
V+ SGT + RP GQI + + P FS C KLD ELE F + + +G P+ I+ A
Sbjct 173 VVTSGTPLHRPQGQILTNPAANPKLPTFSPCKKLDIELELAFFVSTPNDLGHPVHIDKAE 232
Query 102 DHIFGIVLFNDWSARDL 118
DHIFG+VL NDWSARD+
Sbjct 233 DHIFGVVLMNDWSARDI 249
Score = 33.1 bits (74), Expect = 1e-05
Identities = 12/42 (29%), Positives = 26/42 (62%), Gaps = 0/42 (0%)
Query 5 LSSFIDVSPQSDFPIQNLPYGIFSTTVHGKRRVGVALGDWVM 46
++S++ + S F + N+P+GI S++ R +A+GD+ +
Sbjct 1 MASWLQIPKNSPFSLANIPFGIISSSKLSSRVPAIAIGDYAL 42
>O06724 Uncharacterized protein YisK [Bacillus subtilis (strain
168)]
Length=301
Score = 42.4 bits (98), Expect = 7e-09
Identities = 22/45 (49%), Positives = 29/45 (64%), Gaps = 3/45 (7%)
Query 74 KLDFELETGFIIGKSSQVGQPIPIESAWDHIFGIVLFNDWSARDL 118
+LD+E E +IGKS G I E A+DH+FG + ND +ARDL
Sbjct 144 QLDYEGELAVVIGKS---GTRISKEDAYDHVFGYTIVNDITARDL 185
Lambda K H a alpha
0.327 0.143 0.459 0.792 4.96
Gapped
Lambda K H a alpha sigma
0.267 0.0410 0.140 1.90 42.6 43.6
Effective search space used: 374556
Database: bbad014335374fd95329a407b56799ea.SwissProt.fasta
Posted date: May 9, 2024 7:33 PM
Number of letters in database: 4,534
Number of sequences in database: 11
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Neighboring words threshold: 11
Window for multiple hits: 40
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Data ...
