BLASTP 2.12.0+
Reference: Stephen F. Altschul, Thomas L. Madden, Alejandro A.
Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J.
Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of
protein database search programs", Nucleic Acids Res. 25:3389-3402.
Reference for composition-based statistics: Alejandro A. Schaffer,
L. Aravind, Thomas L. Madden, Sergei Shavirin, John L. Spouge, Yuri
I. Wolf, Eugene V. Koonin, and Stephen F. Altschul (2001),
"Improving the accuracy of PSI-BLAST protein database searches with
composition-based statistics and other refinements", Nucleic Acids
Res. 29:2994-3005.
Database: 4f57076a79a711548938ed80c57f5a73.SwissProt.fasta
18 sequences; 5,022 total letters
Query= ACIAD3555
Length=279
Score E
Sequences producing significant alignments: (Bits) Value
P9WGP8 Putative oxidoreductase SadH [Mycobacterium tuberculosis (... 229 5e-78
P9WGP9 Putative oxidoreductase SadH [Mycobacterium tuberculosis (... 229 5e-78
O32291 Uncharacterized oxidoreductase YxnA [Bacillus subtilis (st... 125 3e-37
Q92EK7 Uncharacterized oxidoreductase Lin0452 [Listeria innocua s... 115 4e-34
P14802 Uncharacterized oxidoreductase YoxD [Bacillus subtilis (st... 114 6e-34
P25145 Uncharacterized oxidoreductase Lmo0432 [Listeria monocytog... 114 7e-34
P54554 Uncharacterized oxidoreductase YqjQ [Bacillus subtilis (st... 113 2e-33
Q49WS9 Uncharacterized oxidoreductase SSP1627 [Staphylococcus sap... 112 5e-33
Q0VFE7 Dehydrogenase/reductase SDR family member 7B [Xenopus trop... 112 1e-32
Q5R6U1 Dehydrogenase/reductase SDR family member 7B [Pongo abelii] 112 3e-32
Q6IAN0 Dehydrogenase/reductase SDR family member 7B [Homo sapiens] 111 4e-32
A0A384JQF5 Short-chain dehydrogenase/reductase aba4 [Botryotinia ... 106 7e-31
Q8NBQ5 Estradiol 17-beta-dehydrogenase 11 [Homo sapiens] 107 1e-30
Q14RS1 Short-chain dehydrogenase/reductase aba4 [Botryotinia fuck... 104 5e-30
Q9EQ06 Estradiol 17-beta-dehydrogenase 11 [Mus musculus] 104 8e-30
Q01198 C alpha-dehydrogenase [Sphingobium sp. (strain NBRC 103272... 104 1e-29
Q48436 Diacetyl reductase [(S)-acetoin forming] [Klebsiella pneum... 103 1e-29
Q04520 Diacetyl reductase [(S)-acetoin forming] [Raoultella terri... 101 4e-29
>P9WGP8 Putative oxidoreductase SadH [Mycobacterium tuberculosis
(strain CDC 1551 / Oshkosh)]
Length=276
Score = 229 bits (583), Expect = 5e-78
Identities = 120/270 (44%), Positives = 180/270 (67%), Gaps = 6/270 (2%)
Query 1 MKNFKNKVAAITGAGSGIGQQLAVLLAKEGCHLSLSDVNEQGLVATVELLKPYQIRVTTK 60
M +F+ KVA ITGAGSGIG+ LA+ L+++ L+LSDV+ GL TV L + +V +
Sbjct 1 MSSFEGKVAVITGAGSGIGRALALNLSEKRAKLALSDVDTDGLAKTVRLAQALGAQVKSD 60
Query 61 KVDVSDRQAIKVWAAETVQNHGSVNMIFNNAGVALGSTVEGESYEDLEWVMGINFWGVVY 120
++DV++R+A+ A V + G+V+ ++NNAG+A V+ ++D+E ++ ++FWGVV
Sbjct 61 RLDVAEREAVLAHADAVVAHFGTVHQVYNNAGIAYNGNVDKSEFKDIERIIDVDFWGVVN 120
Query 121 GTKEFLPLIKQSKEGHIINISSLFGLTAQPTQSAYNASKFAVRGFTESLRQELDMEKSGV 180
GTK FLP + S +GHI+NISSLFGL A P QSAYNA+KFAVRGFTE+LRQE+ + + V
Sbjct 121 GTKAFLPHVIASGDGHIVNISSLFGLIAVPGQSAYNAAKFAVRGFTEALRQEMLVARHPV 180
Query 181 SALCVHPGGIRTNIANAAKMSDSLKTLGMHPDKSIQSFNKLLRC-PPEEAARQILEAVRK 239
CVHPGGI+T +A A ++D G + F++ L PE AA+ I+ V K
Sbjct 181 KVTCVHPGGIKTAVARNATVAD-----GEDQQTFAEFFDRRLALHSPEMAAKTIVNGVAK 235
Query 240 DKRRLLIGNDAKTLDLMQRIFPTGYQKVTA 269
+ R+++G +AK +D++ RI + YQ++ A
Sbjct 236 GQARVVVGLEAKAVDVLARIMGSSYQRLVA 265
>P9WGP9 Putative oxidoreductase SadH [Mycobacterium tuberculosis
(strain ATCC 25618 / H37Rv)]
Length=276
Score = 229 bits (583), Expect = 5e-78
Identities = 120/270 (44%), Positives = 180/270 (67%), Gaps = 6/270 (2%)
Query 1 MKNFKNKVAAITGAGSGIGQQLAVLLAKEGCHLSLSDVNEQGLVATVELLKPYQIRVTTK 60
M +F+ KVA ITGAGSGIG+ LA+ L+++ L+LSDV+ GL TV L + +V +
Sbjct 1 MSSFEGKVAVITGAGSGIGRALALNLSEKRAKLALSDVDTDGLAKTVRLAQALGAQVKSD 60
Query 61 KVDVSDRQAIKVWAAETVQNHGSVNMIFNNAGVALGSTVEGESYEDLEWVMGINFWGVVY 120
++DV++R+A+ A V + G+V+ ++NNAG+A V+ ++D+E ++ ++FWGVV
Sbjct 61 RLDVAEREAVLAHADAVVAHFGTVHQVYNNAGIAYNGNVDKSEFKDIERIIDVDFWGVVN 120
Query 121 GTKEFLPLIKQSKEGHIINISSLFGLTAQPTQSAYNASKFAVRGFTESLRQELDMEKSGV 180
GTK FLP + S +GHI+NISSLFGL A P QSAYNA+KFAVRGFTE+LRQE+ + + V
Sbjct 121 GTKAFLPHVIASGDGHIVNISSLFGLIAVPGQSAYNAAKFAVRGFTEALRQEMLVARHPV 180
Query 181 SALCVHPGGIRTNIANAAKMSDSLKTLGMHPDKSIQSFNKLLRC-PPEEAARQILEAVRK 239
CVHPGGI+T +A A ++D G + F++ L PE AA+ I+ V K
Sbjct 181 KVTCVHPGGIKTAVARNATVAD-----GEDQQTFAEFFDRRLALHSPEMAAKTIVNGVAK 235
Query 240 DKRRLLIGNDAKTLDLMQRIFPTGYQKVTA 269
+ R+++G +AK +D++ RI + YQ++ A
Sbjct 236 GQARVVVGLEAKAVDVLARIMGSSYQRLVA 265
>O32291 Uncharacterized oxidoreductase YxnA [Bacillus subtilis
(strain 168)]
Length=356
Score = 125 bits (315), Expect = 3e-37
Identities = 84/262 (32%), Positives = 127/262 (48%), Gaps = 11/262 (4%)
Query 1 MKNFKNKVAAITGAGSGIGQQLAVLLAKEGCHLSLSDVNEQGLVATVELLKPYQIRVTTK 60
+K K++V ITGA SGIG A + A++G + + NE+ L + LK
Sbjct 26 LKKLKDQVIVITGASSGIGLVTARMAAEKGAKVVAAARNEEALKELTDELKEKGHDAIWV 85
Query 61 KVDVSDRQAIKVWAAETVQNHGSVNMIFNNAGVALGSTVEGESYEDLEWVMGINFWGVVY 120
K DV + + A + G + NNA V+ + ED++ + NFWG VY
Sbjct 86 KADVGKEEDVNRIAETAISTFGRFDTWVNNAAVSTFGHAMDVTVEDMKRMFDTNFWGPVY 145
Query 121 GTKEFLP-LIKQSKEGHIINISSLFGLTAQPTQSAYNASKFAVRGFTESLRQELDMEKSG 179
GT+ + + G +IN+ SLFG QS Y ++KFA+ G+TES+R EL+ E++
Sbjct 146 GTRAAVKHYTGRGVPGALINVGSLFGDRGTVIQSTYASAKFALHGWTESIRMELEKEQAP 205
Query 180 VSALCVHPGGIRTNIANAAKMSDSLKTLGMHPDKSIQSFNKLLRCPPEEAARQILEAVRK 239
VS +HPG I T A + DK + ++ PPE A IL A
Sbjct 206 VSVTLIHPGRIDTPYNEHAH---------SYLDKQPAHYRSMI-YPPEAVAEAILFAAEH 255
Query 240 DKRRLLIGNDAKTLDLMQRIFP 261
KR + IG+ AK + ++ +FP
Sbjct 256 PKRDMYIGSQAKAIAMLGALFP 277
>Q92EK7 Uncharacterized oxidoreductase Lin0452 [Listeria innocua
serovar 6a (strain ATCC BAA-680 / CLIP 11262)]
Length=248
Score = 115 bits (287), Expect = 4e-34
Identities = 73/216 (34%), Positives = 107/216 (50%), Gaps = 7/216 (3%)
Query 5 KNKVAAITGAGSGIGQQLAVLLAKEGCHLSLSDVNEQGLVATVELLKPYQIRVTTKKVDV 64
KNKV ITGA SGIG+ A+LLA++G L L+ + L V+ +K K DV
Sbjct 4 KNKVIIITGASSGIGEATAILLAEKGAKLVLAARRVEKLEKIVQTIKASSGEAIFAKTDV 63
Query 65 SDRQAIKVWAAETVQNHGSVNMIFNNAGVALGSTVEGESYEDLEWVMGINFWGVVYGTKE 124
+ R+ K ++ +G V+ IF NAG+ S + ++ E ++ IN GV+ G
Sbjct 64 TKREDNKKLVELAIERYGKVDAIFLNAGIMPNSPLSALKEDEWEQMIDINIKGVLNGIAA 123
Query 125 FLPLIKQSKEGHIINISSLFGLTAQPTQSAYNASKFAVRGFTESLRQELDMEKSGVSALC 184
LP K GHII SS+ GL A P + Y A+K+AVR E LR E E + +
Sbjct 124 VLPSFIAQKSGHIIATSSVAGLKAYPGGAVYGATKWAVRDLMEVLRMESAQEGTNIRTAT 183
Query 185 VHPGGIRTNIANAAK-------MSDSLKTLGMHPDK 213
++P I T + M++ K G+ PD+
Sbjct 184 IYPAAINTELLETITDKETEQGMTNLYKQYGVTPDR 219
>P14802 Uncharacterized oxidoreductase YoxD [Bacillus subtilis
(strain 168)]
Length=238
Score = 114 bits (285), Expect = 6e-34
Identities = 78/242 (32%), Positives = 119/242 (49%), Gaps = 17/242 (7%)
Query 1 MKNFKNKVAAITGAGSGIGQQLAVLLAKEGCHLSLSDVNEQGLVATVELLKPYQIRVTTK 60
M++ ++K A ITG G GIG+ A+ LAKEG ++ L + E +K ++
Sbjct 1 MQSLQHKTALITGGGRGIGRATALALAKEGVNIGLIGRTSANVEKVAEEVKALGVKAAFA 60
Query 61 KVDVSDRQAIKVWAAETVQNHGSVNMIFNNAGVALGSTVEGESYEDLEWVMGINFWGVVY 120
DV D + A+ + G ++++ NNAG++ S ++ E ++ +N GV +
Sbjct 61 AADVKDADQVNQAVAQVKEQLGDIDILINNAGISKFGGFLDLSADEWENIIQVNLMGVYH 120
Query 121 GTKEFLPLIKQSKEGHIINISSLFGLTAQPTQSAYNASKFAVRGFTESLRQELDMEKSGV 180
T+ LP + + K G IINISS G SAY+ASKFAV G TESL QE+ V
Sbjct 121 VTRAVLPEMIERKAGDIINISSTAGQRGAAVTSAYSASKFAVLGLTESLMQEVRKHNIRV 180
Query 181 SALCVHPGGIRTNIANAAKMSDSLKTLGMHPDKSIQSFNKLLRCPPEEAARQILEAVRKD 240
SAL T A+ MS L +P+K +Q PE+ A ++ ++ D
Sbjct 181 SAL--------TPSTVASDMSIELNLTDGNPEKVMQ---------PEDLAEYMVAQLKLD 223
Query 241 KR 242
R
Sbjct 224 PR 225
>P25145 Uncharacterized oxidoreductase Lmo0432 [Listeria monocytogenes
serovar 1/2a (strain ATCC BAA-679 / EGD-e)]
Length=248
Score = 114 bits (285), Expect = 7e-34
Identities = 73/216 (34%), Positives = 107/216 (50%), Gaps = 7/216 (3%)
Query 5 KNKVAAITGAGSGIGQQLAVLLAKEGCHLSLSDVNEQGLVATVELLKPYQIRVTTKKVDV 64
KNKV ITGA SGIG+ A+LLA++G L L+ + L V+ +K K DV
Sbjct 4 KNKVIIITGASSGIGKATALLLAEKGAKLVLAARRVEKLEKIVQTIKANSGEAIFAKTDV 63
Query 65 SDRQAIKVWAAETVQNHGSVNMIFNNAGVALGSTVEGESYEDLEWVMGINFWGVVYGTKE 124
+ R+ K ++ +G V+ IF NAG+ S + ++ E ++ IN GV+ G
Sbjct 64 TKREDNKKLVELAIERYGKVDAIFLNAGIMPNSPLSALKEDEWEQMIDINIKGVLNGIAA 123
Query 125 FLPLIKQSKEGHIINISSLFGLTAQPTQSAYNASKFAVRGFTESLRQELDMEKSGVSALC 184
LP K GHII SS+ GL A P + Y A+K+AVR E LR E E + + +
Sbjct 124 VLPSFIAQKSGHIIATSSVAGLKAYPGGAVYGATKWAVRDLMEVLRMESAQEGTNIRTVT 183
Query 185 VHPGGIRTNIANAAK-------MSDSLKTLGMHPDK 213
++P I T + M+ K G+ PD+
Sbjct 184 IYPAAINTELLETITDKETEQGMTSLYKQYGITPDR 219
>P54554 Uncharacterized oxidoreductase YqjQ [Bacillus subtilis
(strain 168)]
Length=259
Score = 113 bits (283), Expect = 2e-33
Identities = 82/273 (30%), Positives = 136/273 (50%), Gaps = 20/273 (7%)
Query 1 MKNFKNKVAAITGAGSGIGQQLAVLLAKEGCHLSLSDVNEQGLVATV-ELLKPYQIRVTT 59
MK+ K ITGA G+G+++A L A EG H+ LS E L+ ++ + + +
Sbjct 1 MKHIAGKRIWITGASGGLGERIAYLCAAEGAHVLLSARREDRLIEIKRKITEEWSGQCEI 60
Query 60 KKVDVSDRQAIKVWAAETVQNHGSVNMIFNNAGVALGSTVEGESYEDLEWVMGINFWGVV 119
+DV + I A GS++++ NNAG + TV + +D++ + +N +G++
Sbjct 61 FPLDVGRLEDI----ARVRDQIGSIDVLINNAGFGIFETVLDSTLDDMKAMFDVNVFGLI 116
Query 120 YGTKEFLPLIKQSKEGHIINISSLFGLTAQPTQSAYNASKFAVRGFTESLRQELDMEKSG 179
TK LP + + K+GHIINI+S G A P S Y+A+K AV G++ +LR EL +G
Sbjct 117 ACTKAVLPQMLEQKKGHIINIASQAGKIATPKSSLYSATKHAVLGYSNALRMEL--SGTG 174
Query 180 VSALCVHPGGIRTNIANAA-KMSDSLKTLGMHPDKSIQSFNKLLRCPPEEAARQILEAVR 238
+ V+PG I+T+ + A K D K +G P++ A QI A+
Sbjct 175 IYVTTVNPGPIQTDFFSIADKGGDYAKNVGR------------WMLDPDDVAAQITAAIF 222
Query 239 KDKRRLLIGNDAKTLDLMQRIFPTGYQKVTAFA 271
KR + + + ++FP +K+ A
Sbjct 223 TKKREINLPRLMNAGTKLYQLFPALVEKLAGRA 255
>Q49WS9 Uncharacterized oxidoreductase SSP1627 [Staphylococcus
saprophyticus subsp. saprophyticus (strain ATCC 15305 / DSM
20229 / NCIMB 8711 / NCTC 7292 / S-41)]
Length=246
Score = 112 bits (279), Expect = 5e-33
Identities = 69/240 (29%), Positives = 115/240 (48%), Gaps = 8/240 (3%)
Query 1 MKNFKNKVAAITGAGSGIGQQLAVLLAKEGCHLSLSDVNEQGLVATVELLKPYQIRVTTK 60
M N K+KV ITGA SGIG++ LL++ G L L L + K V+ K
Sbjct 1 MNNVKDKVVVITGASSGIGEETVNLLSENGAKLVLGARRLDRLEKIQQ--KVGHDSVSIK 58
Query 61 KVDVSDRQAIKVWAAETVQNHGSVNMIFNNAGVALGSTVEGESYEDLEWVMGINFWGVVY 120
K DV+ + + G ++++ NNAG+ S +E ++ ++ +N GV+Y
Sbjct 59 KTDVTKPDEVNALIETAYNDFGRIDVLINNAGLMPQSFLEKNKQDEWNQMIDVNIKGVLY 118
Query 121 GTKEFLPLIKQSKEGHIINISSLFGLTAQPTQSAYNASKFAVRGFTESLRQELDMEKSGV 180
G LP +++ K GHIIN++S+ G P + Y +K+AVR TE LRQE + S +
Sbjct 119 GIGAVLPYMRKQKSGHIINLASVAGHVVFPGSAVYCGTKYAVRAITEGLRQEEAIVGSNI 178
Query 181 SALCVHPGGIRTNIANAAKMSDSLKTL------GMHPDKSIQSFNKLLRCPPEEAARQIL 234
+ PG + T + + D + + + PD ++ N + P E + + +
Sbjct 179 RTTILSPGAVSTELTDHISDKDMKQDIDELYKNAIKPDAIARAINYAINEPEESSVNEFI 238
>Q0VFE7 Dehydrogenase/reductase SDR family member 7B [Xenopus
tropicalis]
Length=309
Score = 112 bits (280), Expect = 1e-32
Identities = 85/283 (30%), Positives = 142/283 (50%), Gaps = 20/283 (7%)
Query 5 KNKVAAITGAGSGIGQQLAVLLAKEGCHLSLSDVNEQGLVATVELLKPYQIRVTTKKV-- 62
++ V ITGA SG+G++ A + G L L +E+GL V+ L Q+R+ + ++
Sbjct 35 QDAVVVITGATSGLGRECAKVFYAAGTRLVLCGRSEEGLKNLVQELS--QMRIKSAQLHK 92
Query 63 ------DVSDRQAIKVWAAETVQNHGSVNMIFNNAGVALGSTVEGESYEDLEWVMGINFW 116
D+SD +A+ A E + G V+++ NNAG++ T+ VM N++
Sbjct 93 PHMVIFDLSDVEAVNSAANEILHLTGRVDILINNAGISYRGTILDTKVSVDRMVMDTNYF 152
Query 117 GVVYGTKEFLPLIKQSKEGHIINISSLFGLTAQPTQSAYNASKFAVRGFTESLRQELDME 176
G V TK +P + +++ GHI+ ISS+ G + P +SAY+ASK A + F + LR E M
Sbjct 153 GPVALTKALIPSMIKNRRGHIVVISSVQGKISIPFRSAYSASKHATQAFFDCLRAE--MS 210
Query 177 KSGVSALCVHPGGIRTNIANAAKMSDSLKTLGMHPDKSIQSFNKLLRCPPEEAARQILEA 236
+ V+PG I+TN++ A D + + N PEE A+ +L A
Sbjct 211 PYEIDVTVVNPGYIKTNLSLNAVTGDG-------SNYGVMDNNTAEGRTPEEVAQTVLRA 263
Query 237 VRKDKRRLLIGNDAKTLDL-MQRIFPTGYQKVTAFATSLSKKL 278
V + ++ LL+ TL + ++ + PT + A +KL
Sbjct 264 VGERRKELLVAGLVPTLAVYLRTLAPTIFFSFMAARAKKERKL 306
>Q5R6U1 Dehydrogenase/reductase SDR family member 7B [Pongo abelii]
Length=325
Score = 112 bits (279), Expect = 3e-32
Identities = 85/265 (32%), Positives = 136/265 (51%), Gaps = 15/265 (6%)
Query 5 KNKVAAITGAGSGIGQQLAVLLAKEGCHLSLSDVNEQGLVATV-ELLKPYQIRVTTKK-- 61
+N V ITGA SG+G++ A + G L L N L + EL + +V T K
Sbjct 51 RNAVVVITGATSGLGKECAKVFYAAGAKLVLCGRNGGALEELIRELTASHATKVQTHKPY 110
Query 62 ---VDVSDRQAIKVWAAETVQNHGSVNMIFNNAGVALGSTVEGESYEDLEWVMGINFWGV 118
D++D AI AAE +Q G V+++ NNAG++ T+ + + + VM N++G
Sbjct 111 LVTFDLTDSGAIVAAAAEILQCFGYVDILVNNAGISYRGTIMDTTVDVDKRVMETNYFGP 170
Query 119 VYGTKEFLPLIKQSKEGHIINISSLFGLTAQPTQSAYNASKFAVRGFTESLRQELDMEKS 178
V TK LP + + ++GHI+ ISS+ G + P +SAY ASK A + F + LR E ME+
Sbjct 171 VALTKALLPSMIKRRQGHIVAISSIQGKISIPFRSAYAASKHATQAFFDCLRAE--MEQY 228
Query 179 GVSALCVHPGGIRTNIANAAKMSDSLKTLGMHPDKSIQSFNKLLRCPPEEAARQILEAVR 238
+ + PG I TN++ A +D + G+ + Q + P E A+ +L AV
Sbjct 229 EIEVTVISPGYIHTNLSVNAVTADGSR-YGVMDTTTAQGRS------PVEVAQDVLAAVG 281
Query 239 KDKRRLLIGNDAKTLDLMQRIFPTG 263
K K+ +++ + +L + R G
Sbjct 282 KKKKDVILADLLPSLAVYLRTLAPG 306
>Q6IAN0 Dehydrogenase/reductase SDR family member 7B [Homo sapiens]
Length=325
Score = 111 bits (278), Expect = 4e-32
Identities = 85/265 (32%), Positives = 136/265 (51%), Gaps = 15/265 (6%)
Query 5 KNKVAAITGAGSGIGQQLAVLLAKEGCHLSLSDVNEQGLVATV-ELLKPYQIRVTTKK-- 61
+N V ITGA SG+G++ A + G L L N L + EL + +V T K
Sbjct 51 RNAVVVITGATSGLGKECAKVFYAAGAKLVLCGRNGGALEELIRELTASHATKVQTHKPY 110
Query 62 ---VDVSDRQAIKVWAAETVQNHGSVNMIFNNAGVALGSTVEGESYEDLEWVMGINFWGV 118
D++D AI AAE +Q G V+++ NNAG++ T+ + + + VM N++G
Sbjct 111 LVTFDLTDSGAIVAAAAEILQCFGYVDILVNNAGISYRGTIMDTTVDVDKRVMETNYFGP 170
Query 119 VYGTKEFLPLIKQSKEGHIINISSLFGLTAQPTQSAYNASKFAVRGFTESLRQELDMEKS 178
V TK LP + + ++GHI+ ISS+ G + P +SAY ASK A + F + LR E ME+
Sbjct 171 VALTKALLPSMIKRRQGHIVAISSIQGKMSIPFRSAYAASKHATQAFFDCLRAE--MEQY 228
Query 179 GVSALCVHPGGIRTNIANAAKMSDSLKTLGMHPDKSIQSFNKLLRCPPEEAARQILEAVR 238
+ + PG I TN++ A +D + G+ + Q + P E A+ +L AV
Sbjct 229 EIEVTVISPGYIHTNLSVNAITADGSR-YGVMDTTTAQGRS------PVEVAQDVLAAVG 281
Query 239 KDKRRLLIGNDAKTLDLMQRIFPTG 263
K K+ +++ + +L + R G
Sbjct 282 KKKKDVILADLLPSLAVYLRTLAPG 306
>A0A384JQF5 Short-chain dehydrogenase/reductase aba4 [Botryotinia
fuckeliana (strain B05.10)]
Length=258
Score = 106 bits (265), Expect = 7e-31
Identities = 71/212 (33%), Positives = 113/212 (53%), Gaps = 14/212 (7%)
Query 4 FKNKVAAITGAGSGIGQQLAVLLAKEGCHLSLSDVNEQGL-VATVELLKPYQIRVTTKKV 62
F NKV A+TG+ SGIG + A LLA G LSL+D+ E L +L Y + V T KV
Sbjct 6 FTNKVIALTGSASGIGLETAKLLASRGARLSLADIQEDKLKELQAQLESEYYVDVITTKV 65
Query 63 DVSDRQAIKVWAAETVQNHGSVNMIFNNAGVALGST----VEGESYEDLEWVMGINFWGV 118
DV ++ W +T+ N G ++ N AGVA S + + ++ E+V+G+N G
Sbjct 66 DVRKFGEVEAWINKTIDNFGKLDGSANLAGVAPESIGLKGIVEQDLDEWEFVLGVNLTGT 125
Query 119 VYGTKEFLPLIKQSKEGHIINISSLFGLTAQPTQSAYNASKFAVRGFTESLRQELDMEKS 178
+ K L ++ + G I+N SS+ GLT ++Y+++K + G T + +E+ +
Sbjct 126 MNSLKAQLKVM--ANNGSIVNASSIRGLTGAAKNASYSSAKHGIIGLTRTAAKEVGGKGI 183
Query 179 GVSALCVHPGGIRTNIANAAKMSDSLKTLGMH 210
V+A+C PG I T + A+ S +G+H
Sbjct 184 RVNAIC--PGRISTPMLKTAENS-----IGLH 208
>Q8NBQ5 Estradiol 17-beta-dehydrogenase 11 [Homo sapiens]
Length=300
Score = 107 bits (266), Expect = 1e-30
Identities = 77/267 (29%), Positives = 123/267 (46%), Gaps = 19/267 (7%)
Query 2 KNFKNKVAAITGAGSGIGQQLAVLLAKEGCHLSLSDVNEQGLVATVELLKPYQIRVTTKK 61
K+ ++ ITGAG GIG+ A AK L L D+N+ GL T K +V T
Sbjct 32 KSVTGEIVLITGAGHGIGRLTAYEFAKLKSKLVLWDINKHGLEETAAKCKGLGAKVHTFV 91
Query 62 VDVSDRQAIKVWAAETVQNHGSVNMIFNNAGVALGSTVEGESYEDLEWVMGINFWGVVYG 121
VD S+R+ I A + G V+++ NNAGV S + +E +N +
Sbjct 92 VDCSNREDIYSSAKKVKAEIGDVSILVNNAGVVYTSDLFATQDPQIEKTFEVNVLAHFWT 151
Query 122 TKEFLPLIKQSKEGHIINISSLFGLTAQPTQSAYNASKFAVRGFTESLRQEL-DMEKSGV 180
TK FLP + ++ GHI+ ++S G + P AY +SKFA GF ++L EL ++ +GV
Sbjct 152 TKAFLPAMTKNNHGHIVTVASAAGHVSVPFLLAYCSSKFAAVGFHKTLTDELAALQITGV 211
Query 181 SALCVHPGGIRTNIANAAKMSDSLKTLGMHPDKSIQSFNKLLRCPPEEAARQILEAVRKD 240
C+ P N N + + +LG PEE +++ + +
Sbjct 212 KTTCLCP-----NFVNTGFIKNPSTSLGP-------------TLEPEEVVNRLMHGILTE 253
Query 241 KRRLLIGNDAKTLDLMQRIFPTGYQKV 267
++ + I + L ++RI P + V
Sbjct 254 QKMIFIPSSIAFLTTLERILPERFLAV 280
>Q14RS1 Short-chain dehydrogenase/reductase aba4 [Botryotinia
fuckeliana]
Length=258
Score = 104 bits (259), Expect = 5e-30
Identities = 70/212 (33%), Positives = 112/212 (53%), Gaps = 14/212 (7%)
Query 4 FKNKVAAITGAGSGIGQQLAVLLAKEGCHLSLSDVNEQGLVATVELLK-PYQIRVTTKKV 62
F NKV A+TG+ SGIG + A LLA G LSL+D+ E L + Y + V T KV
Sbjct 6 FTNKVIALTGSASGIGLETAKLLASRGARLSLADIQEDKLKELQAXXESEYHVDVITTKV 65
Query 63 DVSDRQAIKVWAAETVQNHGSVNMIFNNAGVALGST----VEGESYEDLEWVMGINFWGV 118
DV ++ W +T+ N G ++ N AGVA S + + ++ E+V+G+N G
Sbjct 66 DVRKFGEVEAWINKTIDNFGKLDGSANLAGVAPESIGLKGIVEQDLDEWEFVLGVNLTGT 125
Query 119 VYGTKEFLPLIKQSKEGHIINISSLFGLTAQPTQSAYNASKFAVRGFTESLRQELDMEKS 178
+ K L ++ + G I+N SS+ GLT ++Y+++K + G T + +E+ +
Sbjct 126 MNSLKAQLKVM--ANNGSIVNASSIRGLTGAAKNASYSSAKHGIIGLTRTAAKEVGGKGI 183
Query 179 GVSALCVHPGGIRTNIANAAKMSDSLKTLGMH 210
V+A+C PG I T + A+ S +G+H
Sbjct 184 RVNAIC--PGRISTPMLKTAENS-----IGLH 208
>Q9EQ06 Estradiol 17-beta-dehydrogenase 11 [Mus musculus]
Length=298
Score = 104 bits (260), Expect = 8e-30
Identities = 73/267 (27%), Positives = 121/267 (45%), Gaps = 19/267 (7%)
Query 2 KNFKNKVAAITGAGSGIGQQLAVLLAKEGCHLSLSDVNEQGLVATVELLKPYQIRVTTKK 61
K+ ++ ITGAG GIG+ A AK L L D+N+ G+ T + +
Sbjct 32 KSVAGEIVLITGAGHGIGRLTAYEFAKLNTKLVLWDINKNGIEETAAKCRKLGAQAHPFV 91
Query 62 VDVSDRQAIKVWAAETVQNHGSVNMIFNNAGVALGSTVEGESYEDLEWVMGINFWGVVYG 121
VD S R+ I A + + G V+++ NNAGV + + +E +N +
Sbjct 92 VDCSQREEIYSAAKKVKEEVGDVSILVNNAGVVYTADLFATQDPQIEKTFEVNVLAHFWT 151
Query 122 TKEFLPLIKQSKEGHIINISSLFGLTAQPTQSAYNASKFAVRGFTESLRQEL-DMEKSGV 180
TK FLP++ ++ GHI+ ++S G T P AY +SKFA GF +L EL + ++GV
Sbjct 152 TKAFLPVMMKNNHGHIVTVASAAGHTVVPFLLAYCSSKFAAVGFHRALTDELAALGRTGV 211
Query 181 SALCVHPGGIRTNIANAAKMSDSLKTLGMHPDKSIQSFNKLLRCPPEEAARQILEAVRKD 240
C+ P N N + + LG PEE ++ + +
Sbjct 212 RTSCLCP-----NFINTGFIKNPSTNLGP-------------TLEPEEVVEHLMHGILTE 253
Query 241 KRRLLIGNDAKTLDLMQRIFPTGYQKV 267
K+ + + + L +++RI P + +V
Sbjct 254 KQMIFVPSSIALLTVLERIVPERFLQV 280
>Q01198 C alpha-dehydrogenase [Sphingobium sp. (strain NBRC 103272
/ SYK-6)]
Length=305
Score = 104 bits (259), Expect = 1e-29
Identities = 75/243 (31%), Positives = 122/243 (50%), Gaps = 8/243 (3%)
Query 1 MKNFKNKVAAITGAGSGIGQQLAVLLAKEGCHLSLSDVNEQGLVATVELLKPYQIRVTTK 60
MK+F+++VA ITG SG G A + + G + ++DV + + V L+ I
Sbjct 1 MKDFQDQVAFITGGASGAGFGQAKVFGQAGAKIVVADVRAEAVEKAVAELEGLGITAHGI 60
Query 61 KVDVSDRQAIKVWAAETVQNHGSV-NMIFNNAGVALGSTVEGESYEDLEWVMGINFWGVV 119
+D+ DR+A A E G ++ N AGV +E +Y+D +W++G+N GV+
Sbjct 61 VLDIMDREAYARAADEVEAVFGQAPTLLSNTAGVNSFGPIEKTTYDDFDWIIGVNLNGVI 120
Query 120 YGTKEFLP-LIKQSKEGHIINISSLFGLTAQPTQSAYNASKFAVRGFTESLRQELDMEKS 178
G F+P +I + GHI+ +SSL G Y+A+K A E RQ L EK
Sbjct 121 NGMVTFVPRMIASGRPGHIVTVSSLGGFMGSALAGPYSAAKAASINLMEGYRQGL--EKY 178
Query 179 GVSALCVHPGGIRTNIANAAKMSDS-LKTLG-MHPDKSIQSFNKLLR--CPPEEAARQIL 234
G+ P I++NIA A+++ + T G + ++SI S + + + PE+ A I
Sbjct 179 GIGVSVCTPANIKSNIAEASRLRPAKYGTSGYVENEESIASLHSIHQHGLEPEKLAEAIK 238
Query 235 EAV 237
+ V
Sbjct 239 KGV 241
>Q48436 Diacetyl reductase [(S)-acetoin forming] [Klebsiella pneumoniae]
Length=256
Score = 103 bits (256), Expect = 1e-29
Identities = 67/189 (35%), Positives = 102/189 (54%), Gaps = 7/189 (4%)
Query 7 KVAAITGAGSGIGQQLAVLLAKEGCHLSLSDVNEQGLVATVELLKPYQIRVTTKKVDVSD 66
KVA +TGAG GIG+ +A+ L K+G ++++D N+ A + R KVDVSD
Sbjct 3 KVALVTGAGQGIGKAIALRLVKDGFAVAIADYNDATAKAVASEINQAGGRAMAVKVDVSD 62
Query 67 RQAIKVWAAETVQNHGSVNMIFNNAGVALGSTVEGESYEDLEWVMGINFWGVVYGTKEFL 126
R + + + G ++I NNAGVA + +E + E ++ V IN GV++G + +
Sbjct 63 RDQVFAAVEQARKTLGGFDVIVNNAGVAPSTPIESITPEIVDKVYNINVKGVIWGIQAAV 122
Query 127 PLIKQSKEGH---IINISSLFGLTAQPTQSAYNASKFAVRGFTESLRQELDMEKSGVSAL 183
K KEGH IIN S G P + Y++SKFAVRG T++ ++L V+
Sbjct 123 EAFK--KEGHGGKIINACSQAGHVGNPELAVYSSSKFAVRGLTQTAARDLAPLGITVNGY 180
Query 184 CVHPGGIRT 192
C PG ++T
Sbjct 181 C--PGIVKT 187
Score = 17.3 bits (33), Expect = 6.5
Identities = 9/45 (20%), Positives = 15/45 (33%), Gaps = 0/45 (0%)
Query 120 YGTKEFLPLIKQSKEGHIINISSLFGLTAQPTQSAYNASKFAVRG 164
YGT EF I + ++++ A P + G
Sbjct 207 YGTAEFAKRITLGRLSEPEDVAACVSYLASPDSDYMTGQSLLIDG 251
>Q04520 Diacetyl reductase [(S)-acetoin forming] [Raoultella terrigena]
Length=241
Score = 101 bits (252), Expect = 4e-29
Identities = 65/189 (34%), Positives = 101/189 (53%), Gaps = 7/189 (4%)
Query 7 KVAAITGAGSGIGQQLAVLLAKEGCHLSLSDVNEQGLVATVELLKPYQIRVTTKKVDVSD 66
KVA +TGAG GIG+ +A+ L K+G ++++D N+ A + R KVDVS
Sbjct 3 KVALVTGAGQGIGKAIALRLVKDGFAVAIADYNDATATAVAAEINQAGGRAVAIKVDVSR 62
Query 67 RQAIKVWAAETVQNHGSVNMIFNNAGVALGSTVEGESYEDLEWVMGINFWGVVYGTKEFL 126
R + + + G N+I NNAG+A + +E + E ++ V IN GV++G + +
Sbjct 63 RDQVFAAVEQARKALGGFNVIVNNAGIAPSTPIESITEEIVDRVYNINVKGVIWGMQAAV 122
Query 127 PLIKQSKEGH---IINISSLFGLTAQPTQSAYNASKFAVRGFTESLRQELDMEKSGVSAL 183
K KEGH I+N S G P + Y++SKFAVRG T++ ++L V+
Sbjct 123 EAFK--KEGHGGKIVNACSQAGHVGNPELAVYSSSKFAVRGLTQTAARDLAPLGITVNGF 180
Query 184 CVHPGGIRT 192
C PG ++T
Sbjct 181 C--PGIVKT 187
Lambda K H a alpha
0.318 0.133 0.378 0.792 4.96
Gapped
Lambda K H a alpha sigma
0.267 0.0410 0.140 1.90 42.6 43.6
Effective search space used: 985608
Database: 4f57076a79a711548938ed80c57f5a73.SwissProt.fasta
Posted date: May 29, 2024 1:39 PM
Number of letters in database: 5,022
Number of sequences in database: 18
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Neighboring words threshold: 11
Window for multiple hits: 40
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Data ...
