BLASTP 2.12.0+
Reference: Stephen F. Altschul, Thomas L. Madden, Alejandro A.
Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J.
Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of
protein database search programs", Nucleic Acids Res. 25:3389-3402.
Reference for composition-based statistics: Alejandro A. Schaffer,
L. Aravind, Thomas L. Madden, Sergei Shavirin, John L. Spouge, Yuri
I. Wolf, Eugene V. Koonin, and Stephen F. Altschul (2001),
"Improving the accuracy of PSI-BLAST protein database searches with
composition-based statistics and other refinements", Nucleic Acids
Res. 29:2994-3005.
Database: 67f1be54e70847992b0003607e86e223.SwissProt.fasta
22 sequences; 11,060 total letters
Query= ACIAD3531
Length=394
Score E
Sequences producing significant alignments: (Bits) Value
P54595 Uncharacterized protein YhcK [Bacillus subtilis (strain 168)] 106 1e-28
Q3Z1N3 Diguanylate cyclase DosC [Shigella sonnei (strain Ss046)] 104 1e-27
Q8X8Q3 Diguanylate cyclase DgcM [Escherichia coli O157:H7] 103 3e-27
P77302 Diguanylate cyclase DgcM [Escherichia coli (strain K12)] 103 3e-27
Q320T0 Diguanylate cyclase DosC [Shigella boydii serotype 4 (stra... 101 1e-26
P0AA90 Diguanylate cyclase DosC [Escherichia coli O157:H7] 101 1e-26
P0AA89 Diguanylate cyclase DosC [Escherichia coli (strain K12)] 101 1e-26
Q9KKZ4 Diguanylate cyclase VdcA [Vibrio cholerae serotype O1 (str... 99.0 3e-26
Q32HJ0 Probable diguanylate cyclase DgcQ [Shigella dysenteriae se... 100 7e-26
Q8XB92 Probable diguanylate cyclase DgcQ [Escherichia coli O157:H7] 100 7e-26
P76330 Probable diguanylate cyclase DgcQ [Escherichia coli (strai... 100 7e-26
Q3Z0N3 Probable diguanylate cyclase DgcQ [Shigella sonnei (strain... 100 7e-26
Q1RAI4 Probable diguanylate cyclase DgcQ [Escherichia coli (strai... 100 7e-26
Q8FGJ7 Probable diguanylate cyclase DgcQ [Escherichia coli O6:H1 ... 100 7e-26
Q83KM9 Putative diguanylate cyclase DgcQ [Shigella flexneri] 98.6 2e-25
Q9HT84 Diguanylate cyclase DgcP [Pseudomonas aeruginosa (strain A... 97.4 7e-25
A0A0H2ZJS2 Diguanylate cyclase DgcP [Pseudomonas aeruginosa (stra... 97.1 9e-25
B8GZM2 Diguanylate cyclase [Caulobacter vibrioides (strain NA1000... 95.1 2e-24
Q9A5I5 Diguanylate cyclase [Caulobacter vibrioides (strain ATCC 1... 95.1 2e-24
Q73RG3 Diguanylate cyclase A [Treponema denticola (strain ATCC 35... 92.4 9e-24
P75908 Probable diguanylate cyclase DgcT [Escherichia coli (strai... 90.9 6e-23
P77334 Cyclic di-GMP phosphodiesterase PdeR [Escherichia coli (st... 90.1 2e-22
>P54595 Uncharacterized protein YhcK [Bacillus subtilis (strain
168)]
Length=359
Score = 106 bits (264), Expect = 1e-28
Identities = 64/166 (39%), Positives = 87/166 (52%), Gaps = 5/166 (3%)
Query 222 EIKRLSQLDFLTNLLNRRSIHQVLDHFHQTRAEK---NYAVILLDLDHFKQINDQYGHHV 278
+ K + DFLT + NRR + +Q A+ +A+I +D+DHFK INDQYGHH
Sbjct 187 QYKFQAHFDFLTGVYNRRKFEETTKALYQQAADTPHFQFALIYMDIDHFKTINDQYGHHE 246
Query 279 GDQVLIAISECLTQHVHPLNNIGRFGGEEFIILIPETSLSAAREIAECCRLAIQQLNIAT 338
GDQVL + L Q + + R GGEEF +L+P SL A IAE R + I
Sbjct 247 GDQVLKELGLRLKQTIRNTDPAARIGGEEFAVLLPNCSLDKAARIAERIRSTVSDAPIVL 306
Query 339 TQ-DNIQLSASFGVA-ISSLQYEASQILTQADQALYFAKACGRNQV 382
T D + ++ S G A + + + ADQ LY AK GRN+V
Sbjct 307 TNGDELSVTISLGAAHYPNNTEQPGSLPILADQMLYKAKETGRNRV 352
>Q3Z1N3 Diguanylate cyclase DosC [Shigella sonnei (strain Ss046)]
Length=460
Score = 104 bits (260), Expect = 1e-27
Identities = 60/175 (34%), Positives = 102/175 (58%), Gaps = 4/175 (2%)
Query 212 LLSQWREREDEIKRLSQ-LDFLTNLLNRRSIHQVLDH--FHQTRAEKNYAVILLDLDHFK 268
+++ RE +E+ R +D LT LLNRR + + H R +V+++D+D FK
Sbjct 279 IITLLRELFEEVSRHEVGMDVLTKLLNRRFLPTIFKREIAHANRTGTPLSVLIIDVDKFK 338
Query 269 QINDQYGHHVGDQVLIAISECLTQHVHPLNNIGRFGGEEFIILIPETSLSAAREIAECCR 328
+IND +GH+ GD++L +S+ +VH + + R+GG+EFII++ E S + AE R
Sbjct 339 EINDTWGHNTGDEILRKVSQAFYDNVHSSDYVFRYGGDEFIIVLTEASENETLRTAERIR 398
Query 329 LAIQQLNI-ATTQDNIQLSASFGVAISSLQYEASQILTQADQALYFAKACGRNQV 382
+++ + A ++I LS S G A+ + + +++ AD+ALY AK GRN+V
Sbjct 399 SRVEKTKLKAANGEDIALSLSIGAAMFNGHPDYERLIQIADEALYIAKRRGRNRV 453
>Q8X8Q3 Diguanylate cyclase DgcM [Escherichia coli O157:H7]
Length=410
Score = 103 bits (256), Expect = 3e-27
Identities = 55/172 (32%), Positives = 97/172 (56%), Gaps = 5/172 (3%)
Query 213 LSQWREREDEIKRLSQLDFLTNLLNRRSIHQVLD--HFHQTRAEKNYAVILLDLDHFKQI 270
+++ + E++++ + D +T LLNRR + + + ++Y+++L+D D FK I
Sbjct 239 ITEQKRLEEQLEHAAHHDAMTGLLNRRQFYHITEPGQMQHLAIAQDYSLLLIDTDRFKHI 298
Query 271 NDQYGHHVGDQVLIAISECLTQHVHPLNNIGRFGGEEFIILIPETSLSAAREIAECCRLA 330
ND YGH GD+VL A++ L + + R+GGEEF++L+P T L A +AE R++
Sbjct 299 NDLYGHSKGDEVLCALARTLESCARKGDLVFRWGGEEFVLLLPRTPLDTALSLAETIRVS 358
Query 331 IQQLNIATTQDNIQLSASFGVAISSLQYEASQILTQADQALYFAKACGRNQV 382
+ +++I+ + + S GVA ++ + D ALY AK GRN+V
Sbjct 359 VAKVSISGLP---RFTVSIGVAHHEGNESIDELFKRVDDALYRAKNDGRNRV 407
>P77302 Diguanylate cyclase DgcM [Escherichia coli (strain K12)]
Length=410
Score = 103 bits (256), Expect = 3e-27
Identities = 55/172 (32%), Positives = 97/172 (56%), Gaps = 5/172 (3%)
Query 213 LSQWREREDEIKRLSQLDFLTNLLNRRSIHQVLD--HFHQTRAEKNYAVILLDLDHFKQI 270
+++ + E++++ + D +T LLNRR + + + ++Y+++L+D D FK I
Sbjct 239 ITEQKRLEEQLEHAAHHDAMTGLLNRRQFYHITEPGQMQHLAIAQDYSLLLIDTDRFKHI 298
Query 271 NDQYGHHVGDQVLIAISECLTQHVHPLNNIGRFGGEEFIILIPETSLSAAREIAECCRLA 330
ND YGH GD+VL A++ L + + R+GGEEF++L+P T L A +AE R++
Sbjct 299 NDLYGHSKGDEVLCALARTLESCARKGDLVFRWGGEEFVLLLPRTPLDTALSLAETIRVS 358
Query 331 IQQLNIATTQDNIQLSASFGVAISSLQYEASQILTQADQALYFAKACGRNQV 382
+ +++I+ + + S GVA ++ + D ALY AK GRN+V
Sbjct 359 VAKVSISGLP---RFTVSIGVAHHEGNESIDELFKRVDDALYRAKNDGRNRV 407
>Q320T0 Diguanylate cyclase DosC [Shigella boydii serotype 4 (strain
Sb227)]
Length=460
Score = 101 bits (252), Expect = 1e-26
Identities = 59/175 (34%), Positives = 101/175 (58%), Gaps = 4/175 (2%)
Query 212 LLSQWREREDEIKRLSQ-LDFLTNLLNRRSIHQVLDH--FHQTRAEKNYAVILLDLDHFK 268
+++ RE +E+ R +D LT LLNRR + + H R +V+++D+D FK
Sbjct 279 IITLLRELFEEVSRHEVGMDVLTKLLNRRFLPTIFKREIAHANRTGTPLSVLIIDVDKFK 338
Query 269 QINDQYGHHVGDQVLIAISECLTQHVHPLNNIGRFGGEEFIILIPETSLSAAREIAECCR 328
+IND +GH+ GD++L +S+ +V + + R+GG+EFII++ E S + AE R
Sbjct 339 EINDTWGHNTGDEILRKVSQAFYDNVRSSDYVFRYGGDEFIIVLTEASENETLRTAERIR 398
Query 329 LAIQQLNI-ATTQDNIQLSASFGVAISSLQYEASQILTQADQALYFAKACGRNQV 382
+++ + A ++I LS S G A+ + + +++ AD+ALY AK GRN+V
Sbjct 399 SRVEKTKLKAANGEDIALSLSIGAAMFNGHPDYERLIQIADEALYIAKRRGRNRV 453
>P0AA90 Diguanylate cyclase DosC [Escherichia coli O157:H7]
Length=460
Score = 101 bits (252), Expect = 1e-26
Identities = 59/175 (34%), Positives = 101/175 (58%), Gaps = 4/175 (2%)
Query 212 LLSQWREREDEIKRLSQ-LDFLTNLLNRRSIHQVLDH--FHQTRAEKNYAVILLDLDHFK 268
+++ RE +E+ R +D LT LLNRR + + H R +V+++D+D FK
Sbjct 279 IITLLRELFEEVSRHEVGMDVLTKLLNRRFLPTIFKREIAHANRTGTPLSVLIIDVDKFK 338
Query 269 QINDQYGHHVGDQVLIAISECLTQHVHPLNNIGRFGGEEFIILIPETSLSAAREIAECCR 328
+IND +GH+ GD++L +S+ +V + + R+GG+EFII++ E S + AE R
Sbjct 339 EINDTWGHNTGDEILRKVSQAFYDNVRSSDYVFRYGGDEFIIVLTEASENETLRTAERIR 398
Query 329 LAIQQLNI-ATTQDNIQLSASFGVAISSLQYEASQILTQADQALYFAKACGRNQV 382
+++ + A ++I LS S G A+ + + +++ AD+ALY AK GRN+V
Sbjct 399 SRVEKTKLKAANGEDIALSLSIGAAMFNGHPDYERLIQIADEALYIAKRRGRNRV 453
>P0AA89 Diguanylate cyclase DosC [Escherichia coli (strain K12)]
Length=460
Score = 101 bits (252), Expect = 1e-26
Identities = 59/175 (34%), Positives = 101/175 (58%), Gaps = 4/175 (2%)
Query 212 LLSQWREREDEIKRLSQ-LDFLTNLLNRRSIHQVLDH--FHQTRAEKNYAVILLDLDHFK 268
+++ RE +E+ R +D LT LLNRR + + H R +V+++D+D FK
Sbjct 279 IITLLRELFEEVSRHEVGMDVLTKLLNRRFLPTIFKREIAHANRTGTPLSVLIIDVDKFK 338
Query 269 QINDQYGHHVGDQVLIAISECLTQHVHPLNNIGRFGGEEFIILIPETSLSAAREIAECCR 328
+IND +GH+ GD++L +S+ +V + + R+GG+EFII++ E S + AE R
Sbjct 339 EINDTWGHNTGDEILRKVSQAFYDNVRSSDYVFRYGGDEFIIVLTEASENETLRTAERIR 398
Query 329 LAIQQLNI-ATTQDNIQLSASFGVAISSLQYEASQILTQADQALYFAKACGRNQV 382
+++ + A ++I LS S G A+ + + +++ AD+ALY AK GRN+V
Sbjct 399 SRVEKTKLKAANGEDIALSLSIGAAMFNGHPDYERLIQIADEALYIAKRRGRNRV 453
>Q9KKZ4 Diguanylate cyclase VdcA [Vibrio cholerae serotype O1
(strain ATCC 39315 / El Tor Inaba N16961)]
Length=339
Score = 99.0 bits (245), Expect = 3e-26
Identities = 61/173 (35%), Positives = 97/173 (56%), Gaps = 5/173 (3%)
Query 213 LSQWREREDEIKRLSQLDFLTNLLNRRSIHQVLDHFHQTRAEKNYAVILLDLDHFKQIND 272
+S+ +E+ ++++ + D L+ L NRR+ D F A + ++I+LD+DHFK +ND
Sbjct 166 ISRLKEQLAKVQKDALFDSLSGLYNRRAFDG--DMFTLIHAGQQVSLIMLDIDHFKALND 223
Query 273 QYGHHVGDQVLIAISECLTQHVHPLNNIGRFGGEEFIILIPETSLSAAREIAECCRLAIQ 332
YGH GDQ++ AI++ L R+GGEEF ++ P SL AR+ AE R +I+
Sbjct 224 NYGHLFGDQIIRAIAKRLQSLCRDGVTAYRYGGEEFALIAPHKSLRIARQFAESVRRSIE 283
Query 333 QLNI---ATTQDNIQLSASFGVAISSLQYEASQILTQADQALYFAKACGRNQV 382
+L + + Q ++ASFGV ++ +AD LY AK GRN+V
Sbjct 284 KLTVKDRRSGQSVGSITASFGVVEKIEGDSLESLIGRADGLLYEAKNLGRNRV 336
>Q32HJ0 Probable diguanylate cyclase DgcQ [Shigella dysenteriae
serotype 1 (strain Sd197)]
Length=564
Score = 100 bits (248), Expect = 7e-26
Identities = 65/192 (34%), Positives = 109/192 (57%), Gaps = 8/192 (4%)
Query 197 FSVPILIGFFGLFEILLSQWREREDEIKRLSQLDFLTNLLNRRSIHQV---LDHFHQTRA 253
F+ +LI ++ + ++S + ++ + D LT L NR ++ + L QT
Sbjct 369 FTTMLLISWY-VIRRMVSNMYVLQSSLQWQAWHDTLTRLYNRGALFEKARPLAKLCQTH- 426
Query 254 EKNYAVILLDLDHFKQINDQYGHHVGDQVLIAISECLTQHVHPLNNIGRFGGEEFIILIP 313
+ ++VI +DLDHFK IND++GH GD+VL + ++ + + GR GGEEF +++P
Sbjct 427 QHPFSVIQVDLDHFKAINDRFGHQAGDRVLSHAAGLISSSLRAQDVAGRVGGEEFCVILP 486
Query 314 ETSLSAAREIAECCRLAIQQLNIATTQD-NIQLSASFGVAIS--SLQYEASQILTQADQA 370
SL+ A E+AE RL + + + + I++SAS GV+ S + Y+ Q+ + AD+
Sbjct 487 GASLTEAAEVAERIRLKLNEKEMLIAKSTTIRISASLGVSSSEETGDYDFEQLQSLADRR 546
Query 371 LYFAKACGRNQV 382
LY AK GRN+V
Sbjct 547 LYLAKQAGRNRV 558
>Q8XB92 Probable diguanylate cyclase DgcQ [Escherichia coli O157:H7]
Length=564
Score = 100 bits (248), Expect = 7e-26
Identities = 65/192 (34%), Positives = 109/192 (57%), Gaps = 8/192 (4%)
Query 197 FSVPILIGFFGLFEILLSQWREREDEIKRLSQLDFLTNLLNRRSIHQV---LDHFHQTRA 253
F+ +LI ++ + ++S + ++ + D LT L NR ++ + L QT
Sbjct 369 FTTMLLISWY-VIRRMVSNMYVLQSSLQWQAWHDTLTRLYNRGALFEKARPLAKLCQTH- 426
Query 254 EKNYAVILLDLDHFKQINDQYGHHVGDQVLIAISECLTQHVHPLNNIGRFGGEEFIILIP 313
+ ++VI +DLDHFK IND++GH GD+VL + ++ + + GR GGEEF +++P
Sbjct 427 QHPFSVIQVDLDHFKAINDRFGHQAGDRVLSHAAGLISSSLRAQDVAGRVGGEEFCVILP 486
Query 314 ETSLSAAREIAECCRLAIQQLNIATTQD-NIQLSASFGVAIS--SLQYEASQILTQADQA 370
SL+ A E+AE RL + + + + I++SAS GV+ S + Y+ Q+ + AD+
Sbjct 487 GASLTEAAEVAERIRLKLNEKEMLIAKSTTIRISASLGVSSSEETGDYDFEQLQSLADRR 546
Query 371 LYFAKACGRNQV 382
LY AK GRN+V
Sbjct 547 LYLAKQAGRNRV 558
>P76330 Probable diguanylate cyclase DgcQ [Escherichia coli (strain
K12)]
Length=564
Score = 100 bits (248), Expect = 7e-26
Identities = 65/192 (34%), Positives = 109/192 (57%), Gaps = 8/192 (4%)
Query 197 FSVPILIGFFGLFEILLSQWREREDEIKRLSQLDFLTNLLNRRSIHQV---LDHFHQTRA 253
F+ +LI ++ + ++S + ++ + D LT L NR ++ + L QT
Sbjct 369 FTTMLLISWY-VIRRMVSNMYVLQSSLQWQAWHDTLTRLYNRGALFEKARPLAKLCQTH- 426
Query 254 EKNYAVILLDLDHFKQINDQYGHHVGDQVLIAISECLTQHVHPLNNIGRFGGEEFIILIP 313
+ ++VI +DLDHFK IND++GH GD+VL + ++ + + GR GGEEF +++P
Sbjct 427 QHPFSVIQVDLDHFKAINDRFGHQAGDRVLSHAAGLISSSLRAQDVAGRVGGEEFCVILP 486
Query 314 ETSLSAAREIAECCRLAIQQLNIATTQD-NIQLSASFGVAIS--SLQYEASQILTQADQA 370
SL+ A E+AE RL + + + + I++SAS GV+ S + Y+ Q+ + AD+
Sbjct 487 GASLTEAAEVAERIRLKLNEKEMLIAKSTTIRISASLGVSSSEETGDYDFEQLQSLADRR 546
Query 371 LYFAKACGRNQV 382
LY AK GRN+V
Sbjct 547 LYLAKQAGRNRV 558
>Q3Z0N3 Probable diguanylate cyclase DgcQ [Shigella sonnei (strain
Ss046)]
Length=569
Score = 100 bits (248), Expect = 7e-26
Identities = 65/192 (34%), Positives = 109/192 (57%), Gaps = 8/192 (4%)
Query 197 FSVPILIGFFGLFEILLSQWREREDEIKRLSQLDFLTNLLNRRSIHQV---LDHFHQTRA 253
F+ +LI ++ + ++S + ++ + D LT L NR ++ + L QT
Sbjct 374 FTTMLLISWY-VIRRMVSNMYVLQSSLQWQAWHDTLTRLYNRGALFEKARPLAKLCQTH- 431
Query 254 EKNYAVILLDLDHFKQINDQYGHHVGDQVLIAISECLTQHVHPLNNIGRFGGEEFIILIP 313
+ ++VI +DLDHFK IND++GH GD+VL + ++ + + GR GGEEF +++P
Sbjct 432 QHPFSVIQVDLDHFKAINDRFGHQAGDRVLSHAAGLISSSLRAQDVAGRVGGEEFCVILP 491
Query 314 ETSLSAAREIAECCRLAIQQLNIATTQD-NIQLSASFGVAIS--SLQYEASQILTQADQA 370
SL+ A E+AE RL + + + + I++SAS GV+ S + Y+ Q+ + AD+
Sbjct 492 GASLTEAAEVAERIRLKLNEKEMLIAKSTTIRISASLGVSSSEETGDYDFEQLQSLADRR 551
Query 371 LYFAKACGRNQV 382
LY AK GRN+V
Sbjct 552 LYLAKQAGRNRV 563
>Q1RAI4 Probable diguanylate cyclase DgcQ [Escherichia coli (strain
UTI89 / UPEC)]
Length=569
Score = 100 bits (248), Expect = 7e-26
Identities = 65/192 (34%), Positives = 109/192 (57%), Gaps = 8/192 (4%)
Query 197 FSVPILIGFFGLFEILLSQWREREDEIKRLSQLDFLTNLLNRRSIHQV---LDHFHQTRA 253
F+ +LI ++ + ++S + ++ + D LT L NR ++ + L QT
Sbjct 374 FTTMLLISWY-VIRRMVSNMYVLQSSLQWQAWHDTLTRLYNRGALFEKARPLAKLCQTH- 431
Query 254 EKNYAVILLDLDHFKQINDQYGHHVGDQVLIAISECLTQHVHPLNNIGRFGGEEFIILIP 313
+ ++VI +DLDHFK IND++GH GD+VL + ++ + + GR GGEEF +++P
Sbjct 432 QHPFSVIQVDLDHFKAINDRFGHQAGDRVLSHAAGLISSSLRAQDVAGRVGGEEFCVILP 491
Query 314 ETSLSAAREIAECCRLAIQQLNIATTQD-NIQLSASFGVAIS--SLQYEASQILTQADQA 370
SL+ A E+AE RL + + + + I++SAS GV+ S + Y+ Q+ + AD+
Sbjct 492 GASLTQAAEVAERIRLKLNEKEMLIAKSTTIRISASLGVSSSEETGDYDFEQLQSLADRR 551
Query 371 LYFAKACGRNQV 382
LY AK GRN+V
Sbjct 552 LYLAKQAGRNRV 563
>Q8FGJ7 Probable diguanylate cyclase DgcQ [Escherichia coli O6:H1
(strain CFT073 / ATCC 700928 / UPEC)]
Length=569
Score = 100 bits (248), Expect = 7e-26
Identities = 61/162 (38%), Positives = 94/162 (58%), Gaps = 13/162 (8%)
Query 230 DFLTNLLNRRSIHQV------LDHFHQTRAEKNYAVILLDLDHFKQINDQYGHHVGDQVL 283
D LT L NR ++ + L H HQ ++VI +DLDHFK IND++GH GD+VL
Sbjct 406 DTLTRLYNRGALFEKACPLAKLCHTHQ----HPFSVIQVDLDHFKAINDRFGHQAGDRVL 461
Query 284 IAISECLTQHVHPLNNIGRFGGEEFIILIPETSLSAAREIAECCRLAIQQLNIATTQD-N 342
+ ++ + + GR GGEEF +++P +L+ A E+AE RL + + + +
Sbjct 462 SHAAGLISSSLRAQDIAGRVGGEEFCVILPGANLTQAAEVAERIRLKLNEKEMLIAKSTT 521
Query 343 IQLSASFGVAIS--SLQYEASQILTQADQALYFAKACGRNQV 382
I++SAS GV+ S + Y+ Q+ + AD+ LY AK GRN+V
Sbjct 522 IRISASLGVSSSEETGDYDFEQLQSLADRRLYLAKQAGRNRV 563
Score = 18.5 bits (36), Expect = 9.9
Identities = 19/66 (29%), Positives = 27/66 (41%), Gaps = 13/66 (20%)
Query 35 LLSSGMILSWIVWKLFVLLHPELWKYVNIRLIEIDMWVCSLTLTV---LIF-----LMYL 86
L +S ++LSW V + V YV ++ W +LT +F L L
Sbjct 373 LFTSMLLLSWYVIRRMVSN-----MYVLQSSLQWQAWHDTLTRLYNRGALFEKACPLAKL 427
Query 87 CHYHAH 92
CH H H
Sbjct 428 CHTHQH 433
>Q83KM9 Putative diguanylate cyclase DgcQ [Shigella flexneri]
Length=569
Score = 98.6 bits (244), Expect = 2e-25
Identities = 60/159 (38%), Positives = 94/159 (59%), Gaps = 7/159 (4%)
Query 230 DFLTNLLNRRSIHQV---LDHFHQTRAEKNYAVILLDLDHFKQINDQYGHHVGDQVLIAI 286
D LT L NR ++ + L QT + ++VI +DLDHFK IND++GH GD+VL
Sbjct 406 DTLTRLYNRGALFEKARPLAKLCQTH-QHPFSVIQVDLDHFKAINDRFGHQAGDRVLSHA 464
Query 287 SECLTQHVHPLNNIGRFGGEEFIILIPETSLSAAREIAECCRLAIQQLNIATTQD-NIQL 345
+ ++ + + GR GGEEF +++P +L+ A E+AE RL + + + + I++
Sbjct 465 AGLISSSLRAQDVAGRVGGEEFCVILPGANLTQAAEVAERIRLKLNEKEMLIAKSTTIRI 524
Query 346 SASFGVAIS--SLQYEASQILTQADQALYFAKACGRNQV 382
SAS GV+ S + Y+ Q+ + AD+ LY AK GRN+V
Sbjct 525 SASLGVSSSEETGDYDFEQLQSLADRRLYLAKQAGRNRV 563
>Q9HT84 Diguanylate cyclase DgcP [Pseudomonas aeruginosa (strain
ATCC 15692 / DSM 22644 / CIP 104116 / JCM 14847 / LMG 12228
/ 1C / PRS 101 / PAO1)]
Length=671
Score = 97.4 bits (241), Expect = 7e-25
Identities = 57/155 (37%), Positives = 86/155 (55%), Gaps = 2/155 (1%)
Query 230 DFLTNLLNRRSIHQVLDHFHQTRAEKNYAVIL--LDLDHFKQINDQYGHHVGDQVLIAIS 287
D LT L NR ++ + L+ R ++L LD+DHFK+IND +GH GD+VL I+
Sbjct 514 DPLTGLPNRAALSERLEQEVARRHRDGGDLLLAVLDIDHFKRINDDFGHLAGDKVLKIIA 573
Query 288 ECLTQHVHPLNNIGRFGGEEFIILIPETSLSAAREIAECCRLAIQQLNIATTQDNIQLSA 347
L + + + I RFGGEEF++L+P TSL A R++ E R AI + + ++
Sbjct 574 GELRKRLRQADFIARFGGEEFVVLLPATSLEAGRQLLERLRAAIAACPFHFKGEPLSITC 633
Query 348 SFGVAISSLQYEASQILTQADQALYFAKACGRNQV 382
S G+ + +ADQALY AK GR+++
Sbjct 634 SAGITAFEGNEAGEAVFERADQALYRAKRAGRDRL 668
>A0A0H2ZJS2 Diguanylate cyclase DgcP [Pseudomonas aeruginosa (strain
UCBPP-PA14)]
Length=671
Score = 97.1 bits (240), Expect = 9e-25
Identities = 57/155 (37%), Positives = 86/155 (55%), Gaps = 2/155 (1%)
Query 230 DFLTNLLNRRSIHQVLDHFHQTRAEKNYAVIL--LDLDHFKQINDQYGHHVGDQVLIAIS 287
D LT L NR ++ + L+ R ++L LD+DHFK+IND +GH GD+VL I+
Sbjct 514 DPLTGLPNRAALSERLEQEVARRHRDGGDLLLAVLDIDHFKRINDDFGHLAGDKVLKIIA 573
Query 288 ECLTQHVHPLNNIGRFGGEEFIILIPETSLSAAREIAECCRLAIQQLNIATTQDNIQLSA 347
L + + + I RFGGEEF++L+P TSL A R++ E R AI + + ++
Sbjct 574 GELRKRLRQADFIARFGGEEFVVLLPATSLEAGRQLLERLRAAIAACPFHFKGEPLSITC 633
Query 348 SFGVAISSLQYEASQILTQADQALYFAKACGRNQV 382
S G+ + +ADQALY AK GR+++
Sbjct 634 SAGITAFEGNEAGEVVFERADQALYRAKRAGRDRL 668
>B8GZM2 Diguanylate cyclase [Caulobacter vibrioides (strain NA1000
/ CB15N)]
Length=454
Score = 95.1 bits (235), Expect = 2e-24
Identities = 58/171 (34%), Positives = 98/171 (57%), Gaps = 5/171 (3%)
Query 217 REREDEIKRLSQLDFLTNLLNRRSIHQVLDHF--HQTRAEKNYAVILLDLDHFKQINDQY 274
R D L+ D LT L NRR + LD T + +L+D+D FK+IND +
Sbjct 279 RNNLDHSLELAVTDQLTGLHNRRYMTGQLDSLVKRATLGGDPVSALLIDIDFFKKINDTF 338
Query 275 GHHVGDQVLIAISECLTQHVHPLNNIGRFGGEEFIILIPETSLSAAREIAECCRLAI--Q 332
GH +GD+VL + L +V ++ R+GGEEF++++P+T+L+ A IAE R+ +
Sbjct 339 GHDIGDEVLREFALRLASNVRAIDLPCRYGGEEFVVIMPDTALADALRIAERIRMHVSGS 398
Query 333 QLNIATTQDNIQLSASFGVAISSLQYEASQ-ILTQADQALYFAKACGRNQV 382
+A ++ + ++ S GV+ ++ + + + +L +AD+ +Y AKA GRN V
Sbjct 399 PFTVAHGREMLNVTISIGVSATAGEGDTPEALLKRADEGVYQAKASGRNAV 449
>Q9A5I5 Diguanylate cyclase [Caulobacter vibrioides (strain ATCC
19089 / CB15)]
Length=454
Score = 95.1 bits (235), Expect = 2e-24
Identities = 58/171 (34%), Positives = 98/171 (57%), Gaps = 5/171 (3%)
Query 217 REREDEIKRLSQLDFLTNLLNRRSIHQVLDHF--HQTRAEKNYAVILLDLDHFKQINDQY 274
R D L+ D LT L NRR + LD T + +L+D+D FK+IND +
Sbjct 279 RNNLDHSLELAVTDQLTGLHNRRYMTGQLDSLVKRATLGGDPVSALLIDIDFFKKINDTF 338
Query 275 GHHVGDQVLIAISECLTQHVHPLNNIGRFGGEEFIILIPETSLSAAREIAECCRLAI--Q 332
GH +GD+VL + L +V ++ R+GGEEF++++P+T+L+ A IAE R+ +
Sbjct 339 GHDIGDEVLREFALRLASNVRAIDLPCRYGGEEFVVIMPDTALADALRIAERIRMHVSGS 398
Query 333 QLNIATTQDNIQLSASFGVAISSLQYEASQ-ILTQADQALYFAKACGRNQV 382
+A ++ + ++ S GV+ ++ + + + +L +AD+ +Y AKA GRN V
Sbjct 399 PFTVAHGREMLNVTISIGVSATAGEGDTPEALLKRADEGVYQAKASGRNAV 449
>Q73RG3 Diguanylate cyclase A [Treponema denticola (strain ATCC
35405 / DSM 14222 / CIP 103919 / JCM 8153 / KCTC 15104)]
Length=371
Score = 92.4 bits (228), Expect = 9e-24
Identities = 52/167 (31%), Positives = 95/167 (57%), Gaps = 6/167 (4%)
Query 222 EIKRLSQLDFLTNL-LNRRSIHQVLDHFHQTRA----EKNYAVILLDLDHFKQINDQYGH 276
++ ++ D +T+L L +++H + + ++ +++++D+D FK IND YGH
Sbjct 195 QLLEMTTTDIMTHLKLKHYFFTLLMEHLYTINSSGEKKETLSILMIDIDFFKNINDTYGH 254
Query 277 HVGDQVLIAISECLTQHVHPLNNIGRFGGEEFIILIPETSLSAAREIAECCRLAIQQLNI 336
GD VL +++ + + R+GGEEFI+++ TS SAA +AE R ++++ +I
Sbjct 255 AAGDIVLEEVAKIIKSCTRNADTAARYGGEEFIVMLNNTSASAAMAVAERIRKSVEEKSI 314
Query 337 ATTQDNIQLSASFGVAISSLQYE-ASQILTQADQALYFAKACGRNQV 382
I ++ S GV+ + E A I+ +AD+ALY +K GRN+V
Sbjct 315 MYDGKKINVTISIGVSSYNFDLESAKSIVERADKALYESKQNGRNRV 361
>P75908 Probable diguanylate cyclase DgcT [Escherichia coli (strain
K12)]
Length=452
Score = 90.9 bits (224), Expect = 6e-23
Identities = 52/162 (32%), Positives = 85/162 (52%), Gaps = 3/162 (2%)
Query 224 KRLSQLDFLTNLLNRRSIHQVLDHFHQTRAEKNYAVILLDLDHFKQINDQYGHHVGDQVL 283
K ++ D LTN+ NR L + + Y V+++D+DHFK++ND +GH VGDQV+
Sbjct 279 KNIAHRDPLTNIFNRNYFFNELTVQSASAQKTPYCVMIMDIDHFKKVNDTWGHPVGDQVI 338
Query 284 IAISECLTQHVHPLNNIGRFGGEEFIILIPETSLSAAREIAECCRLAIQQLNIATTQDNI 343
+ + + + P + + R GGEEF +L+ + A+ +AE R +++L + I
Sbjct 339 KTVVNIIGKSIRPDDLLARVGGEEFGVLLTDIDTERAKALAERIRENVERLTGDNPEYAI 398
Query 344 QLSASFGVAISSLQYEA---SQILTQADQALYFAKACGRNQV 382
+ + Q A ++I AD ALY AK GRN+V
Sbjct 399 PQKVTISIGAVVTQENALNPNEIYRLADNALYEAKETGRNKV 440
>P77334 Cyclic di-GMP phosphodiesterase PdeR [Escherichia coli
(strain K12)]
Length=661
Score = 90.1 bits (222), Expect = 2e-22
Identities = 59/183 (32%), Positives = 95/183 (52%), Gaps = 3/183 (2%)
Query 213 LSQWREREDEIKRLSQLDFLTNLLNRRSIHQVLDHFHQTRAEKNYAVILLDLDHFKQIND 272
+++ R ++ ++ L+ D +T L NR ++ ++DH V+ LDLD+FK++ND
Sbjct 223 ITEERRAQERLRILANTDSITGLPNRNAMQDLIDHAINHADNNKVGVVYLDLDNFKKVND 282
Query 273 QYGHHVGDQVLIAISECLTQHVHPLNNIGRFGGEEFIILIPETSLSAAREIAECCRLAIQ 332
YGH GDQ+L +S + + + R GG+EF++L TS SA +A L
Sbjct 283 AYGHLFGDQLLRDVSLAILSCLEHDQVLARPGGDEFLVLASNTSQSALEAMASRI-LTRL 341
Query 333 QLNIATTQDNIQLSASFGVAISSLQ-YEASQILTQADQALYFAKACGRNQVRTF-PEYIQ 390
+L + S S G+A+S +++ I+ AD A+Y AK GR Q F PE Q
Sbjct 342 RLPFRIGLIEVYTSCSVGIALSPEHGSDSTAIIRHADTAMYTAKEGGRGQFCVFTPEMNQ 401
Query 391 QNF 393
+ F
Sbjct 402 RVF 404
Lambda K H a alpha
0.330 0.142 0.446 0.792 4.96
Gapped
Lambda K H a alpha sigma
0.267 0.0410 0.140 1.90 42.6 43.6
Effective search space used: 3356480
Database: 67f1be54e70847992b0003607e86e223.SwissProt.fasta
Posted date: May 31, 2024 1:34 PM
Number of letters in database: 11,060
Number of sequences in database: 22
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Neighboring words threshold: 11
Window for multiple hits: 40
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Data ...
