Comparative Genomics

ACIAD3443 / SwissProt Alignments

BLASTP 2.12.0+


Reference: Stephen F. Altschul, Thomas L. Madden, Alejandro A.
Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J.
Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of
protein database search programs", Nucleic Acids Res. 25:3389-3402.


Reference for composition-based statistics: Alejandro A. Schaffer,
L. Aravind, Thomas L. Madden, Sergei Shavirin, John L. Spouge, Yuri
I. Wolf, Eugene V. Koonin, and Stephen F. Altschul (2001),
"Improving the accuracy of PSI-BLAST protein database searches with
composition-based statistics and other refinements", Nucleic Acids
Res. 29:2994-3005.



Database: 2e2b093ba645ced97e24a599ae90bc7f.SwissProt.fasta
           18 sequences; 9,508 total letters



Query= ACIAD3443

Length=449
                                                                      Score     E
Sequences producing significant alignments:                          (Bits)  Value

Q7WT72 1-hydroxycarotenoid 3,4-desaturase [Flavobacterium sp. (st...  42.4    3e-07
Q2YWE8 4,4'-diapophytoene desaturase (4,4'-diaponeurosporene-form...  42.4    3e-07
Q6GDN7 4,4'-diapophytoene desaturase (4,4'-diaponeurosporene-form...  42.0    5e-07
Q8NB78 Lysine-specific histone demethylase 2 [Homo sapiens]           41.6    7e-07
Q31N27 Probable zeta-carotene desaturase [Synechococcus elongatus...  41.2    8e-07
Q7A3E2 4,4'-diapophytoene desaturase (4,4'-diaponeurosporene-form...  41.2    8e-07
Q99R76 4,4'-diapophytoene desaturase (4,4'-diaponeurosporene-form...  41.2    8e-07
Q2FDU6 4,4'-diapophytoene desaturase (4,4'-diaponeurosporene-form...  41.2    8e-07
O07855 4,4'-diapophytoene desaturase (4,4'-diaponeurosporene-form...  41.2    8e-07
Q2FV60 4,4'-diapophytoene desaturase (4,4'-diaponeurosporene-form...  41.2    8e-07
O34399 Glutamate synthase [NADPH] small chain [Bacillus subtilis ...  40.8    1e-06
Q5HCY9 4,4'-diapophytoene desaturase (4,4'-diaponeurosporene-form...  40.8    1e-06
B5U6Y8 L-amino-acid oxidase [Echis ocellatus]                         40.8    1e-06
P86810 L-amino-acid oxidase [Siganus canaliculatus]                   40.8    1e-06
Q8CIG3 Lysine-specific histone demethylase 1B [Mus musculus]          40.8    1e-06
Q8MP06 Senecionine N-oxygenase [Tyria jacobaeae]                      40.4    1e-06
Q96RQ9 L-amino-acid oxidase [Homo sapiens]                            40.4    1e-06
Q48MT7 Renalase [Pseudomonas savastanoi pv. phaseolicola (strain ...  40.0    1e-06


>Q7WT72 1-hydroxycarotenoid 3,4-desaturase [Flavobacterium sp. 
(strain P99-3)]
Length=488

 Score = 42.4 bits (98),  Expect = 3e-07
 Identities = 30/89 (34%), Positives = 42/89 (47%), Gaps = 1/89 (1%)

Query  21   IIGSGMAGLATARILKDAGHAITIFEALPGRGMDSHSIEFEGGVID-APLRVMNPFLWKN  79
            IIGSG+AGLA A  LK  G+ +++FE     G   H+IE  G   D  P     P L   
Sbjct  6    IIGSGIAGLAAALRLKKKGYQVSVFEKNDYAGGKLHAIELGGYRFDLGPSLFTLPHLIDE  65

Query  80   TLSLATHLGMTMFPVRTYMACSWLFEDRT  108
               L   + +    ++   AC + +ED T
Sbjct  66   LHQLFPDVEIDFNYIKKKTACHYFWEDGT  94


>Q2YWE8 4,4'-diapophytoene desaturase (4,4'-diaponeurosporene-forming) 
[Staphylococcus aureus (strain bovine RF122 / ET3-1)]
Length=502

 Score = 42.4 bits (98),  Expect = 3e-07
 Identities = 23/68 (34%), Positives = 38/68 (56%), Gaps = 1/68 (1%)

Query  17  LDIAIIGSGMAGLATARILKDAGHAITIFEALPGRGMDSHSIEFEGGVID-APLRVMNPF  75
           + IA+IG+G+ GLA A  +   GH +TIFE     G   + ++ +G   D  P  VM P 
Sbjct  1   MKIAVIGAGVTGLAAAARIASQGHEVTIFEKNTNVGGRMNQLKKDGFTFDMGPTIVMMPD  60

Query  76  LWKNTLSL  83
           ++K+  ++
Sbjct  61  VYKDVFTM  68


>Q6GDN7 4,4'-diapophytoene desaturase (4,4'-diaponeurosporene-forming) 
[Staphylococcus aureus (strain MRSA252)]
Length=502

 Score = 42.0 bits (97),  Expect = 5e-07
 Identities = 23/68 (34%), Positives = 38/68 (56%), Gaps = 1/68 (1%)

Query  17  LDIAIIGSGMAGLATARILKDAGHAITIFEALPGRGMDSHSIEFEGGVID-APLRVMNPF  75
           + IA+IG+G+ GLA A  +   GH +TIFE     G   + ++ +G   D  P  VM P 
Sbjct  1   MKIAVIGAGVTGLAAAARIASQGHEVTIFEKNNNVGGRMNQLKKDGFTFDMGPAIVMMPD  60

Query  76  LWKNTLSL  83
           ++K+  ++
Sbjct  61  VYKDVFTM  68


>Q8NB78 Lysine-specific histone demethylase 2 [Homo sapiens]
Length=822

 Score = 41.6 bits (96),  Expect = 7e-07
 Identities = 91/413 (22%), Positives = 150/413 (36%), Gaps = 60/413 (15%)

Query  19   IAIIGSGMAGLATARILKDAGHAITIFEA---LPGRGMDSHSIEFEGGVIDAPLRVMNPF  75
            + IIG+G AGLA AR L + G  +T+ EA   + GR  D  S  F+G  +    +++N  
Sbjct  385  VIIIGAGPAGLAAARQLHNFGIKVTVLEAKDRIGGRVWDDKS--FKGVTVGRGAQIVNGC  442

Query  76   LWKNTLSLATHLGMTMFPVRTYMACSWLFEDRTETWLTTTRSRIGNFPIINNRKGLKQYG  135
            +      +   LG++M   +    C  + E    T  T  +    +F  + +        
Sbjct  443  INNPVALMCEQLGISMH--KFGERCDLIQEGGRITDPTIDKRMDFHFNALLDVVS----E  496

Query  136  WRLVKGMLQ---LKTAIHQFFKSKNQDITLAEFINQNDIEEVFWHGAVMPV----LYTVC  188
            WR  K  LQ   L   I + +K+         FI ++ I+     G V+      L   C
Sbjct  497  WRKDKTQLQDVPLGEKIEEIYKA---------FIKESGIQFSELEGQVLQFHLSNLEYAC  547

Query  189  TCNPKTIG--DWPAKPLLVFLRQLTDGDALLRMHGGTPAFVDRLIDGIHIHSGSAIVKVE  246
              N   +    W       F  Q      LL    G    +++L +G+ I   S +  ++
Sbjct  548  GSNLHQVSARSWDHNE---FFAQFAGDHTLLT--PGYSVIIEKLAEGLDIQLKSPVQCID  602

Query  247  QQGDKVLVENALGEQNLFDRVVIATPTDKIDDFLNAEQFADDLALLKQFRFEQ-GDLVIH  305
              GD+V V    G      +V++  P   +     A QF   L+  K       G  +I 
Sbjct  603  YSGDEVQVTTTDGTGYSAQKVLVTVPLALLQK--GAIQFNPPLSEKKMKAINSLGAGIIE  660

Query  306  TDTTVMPPRRKDWSVLSYMMDRKFTRQQFTVWMNAVEPSLVGKSPVFQTWRPVTPIDPKK  365
                  P R  D            ++ Q   +   V PS   K  +F  +  + P     
Sbjct  661  KIALQFPYRFWD------------SKVQGADFFGHVPPS-ASKRGLFAVFYDMDPQKKHS  707

Query  366  IISTVKLTRAVVDSKTVALNTALQQ----------RHKDPERKVFYCGSWSCD  408
            ++ +V    AV   +T+     LQQ            + P+   ++   WS D
Sbjct  708  VLMSVIAGEAVASVRTLDDKQVLQQCMATLRELFKEQEVPDPTKYFVTRWSTD  760


>Q31N27 Probable zeta-carotene desaturase [Synechococcus elongatus 
(strain ATCC 33912 / PCC 7942 / FACHB-805)]
Length=481

 Score = 41.2 bits (95),  Expect = 8e-07
 Identities = 27/71 (38%), Positives = 41/71 (58%), Gaps = 2/71 (3%)

Query  19  IAIIGSGMAGLATARILKDAGHAITIFEALPGRGMDSHS-IEFEGGVIDAPLRVMNPFLW  77
           +AI+G+G+AGLA A  L DAGH + I+++ P  G    S I+ +G  I+  L V   F +
Sbjct  3   VAIVGAGLAGLAAAIDLVDAGHQVAIYDSRPFVGGKVGSWIDADGNHIEMGLHVFF-FNY  61

Query  78  KNTLSLATHLG  88
            N  +L   +G
Sbjct  62  ANLFALMRKVG  72


>Q7A3E2 4,4'-diapophytoene desaturase (4,4'-diaponeurosporene-forming) 
[Staphylococcus aureus (strain N315)]
Length=502

 Score = 41.2 bits (95),  Expect = 8e-07
 Identities = 23/67 (34%), Positives = 37/67 (55%), Gaps = 1/67 (1%)

Query  17  LDIAIIGSGMAGLATARILKDAGHAITIFEALPGRGMDSHSIEFEGGVID-APLRVMNPF  75
           + IA+IG+G+ GLA A  +   GH +TIFE     G   + ++ +G   D  P  VM P 
Sbjct  1   MKIAVIGAGVTGLAAAARIASQGHEVTIFEKNNNVGGRMNQLKKDGFTFDMGPTIVMMPD  60

Query  76  LWKNTLS  82
           ++K+  +
Sbjct  61  VYKDVFT  67


>Q99R76 4,4'-diapophytoene desaturase (4,4'-diaponeurosporene-forming) 
[Staphylococcus aureus (strain Mu50 / ATCC 700699)]
Length=502

 Score = 41.2 bits (95),  Expect = 8e-07
 Identities = 23/67 (34%), Positives = 37/67 (55%), Gaps = 1/67 (1%)

Query  17  LDIAIIGSGMAGLATARILKDAGHAITIFEALPGRGMDSHSIEFEGGVID-APLRVMNPF  75
           + IA+IG+G+ GLA A  +   GH +TIFE     G   + ++ +G   D  P  VM P 
Sbjct  1   MKIAVIGAGVTGLAAAARIASQGHEVTIFEKNNNVGGRMNQLKKDGFTFDMGPTIVMMPD  60

Query  76  LWKNTLS  82
           ++K+  +
Sbjct  61  VYKDVFT  67


>Q2FDU6 4,4'-diapophytoene desaturase (4,4'-diaponeurosporene-forming) 
[Staphylococcus aureus (strain USA300)]
Length=502

 Score = 41.2 bits (95),  Expect = 8e-07
 Identities = 23/67 (34%), Positives = 37/67 (55%), Gaps = 1/67 (1%)

Query  17  LDIAIIGSGMAGLATARILKDAGHAITIFEALPGRGMDSHSIEFEGGVID-APLRVMNPF  75
           + IA+IG+G+ GLA A  +   GH +TIFE     G   + ++ +G   D  P  VM P 
Sbjct  1   MKIAVIGAGVTGLAAAARIASQGHEVTIFEKNNNVGGRMNQLKKDGFTFDMGPTIVMMPD  60

Query  76  LWKNTLS  82
           ++K+  +
Sbjct  61  VYKDVFT  67


>O07855 4,4'-diapophytoene desaturase (4,4'-diaponeurosporene-forming) 
[Staphylococcus aureus (strain Newman)]
Length=502

 Score = 41.2 bits (95),  Expect = 8e-07
 Identities = 23/67 (34%), Positives = 37/67 (55%), Gaps = 1/67 (1%)

Query  17  LDIAIIGSGMAGLATARILKDAGHAITIFEALPGRGMDSHSIEFEGGVID-APLRVMNPF  75
           + IA+IG+G+ GLA A  +   GH +TIFE     G   + ++ +G   D  P  VM P 
Sbjct  1   MKIAVIGAGVTGLAAAARIASQGHEVTIFEKNNNVGGRMNQLKKDGFTFDMGPTIVMMPD  60

Query  76  LWKNTLS  82
           ++K+  +
Sbjct  61  VYKDVFT  67


>Q2FV60 4,4'-diapophytoene desaturase (4,4'-diaponeurosporene-forming) 
[Staphylococcus aureus (strain NCTC 8325 / PS 47)]
Length=502

 Score = 41.2 bits (95),  Expect = 8e-07
 Identities = 23/67 (34%), Positives = 37/67 (55%), Gaps = 1/67 (1%)

Query  17  LDIAIIGSGMAGLATARILKDAGHAITIFEALPGRGMDSHSIEFEGGVID-APLRVMNPF  75
           + IA+IG+G+ GLA A  +   GH +TIFE     G   + ++ +G   D  P  VM P 
Sbjct  1   MKIAVIGAGVTGLAAAARIASQGHEVTIFEKNNNVGGRMNQLKKDGFTFDMGPTIVMMPD  60

Query  76  LWKNTLS  82
           ++K+  +
Sbjct  61  VYKDVFT  67


>O34399 Glutamate synthase [NADPH] small chain [Bacillus subtilis 
(strain 168)]
Length=493

 Score = 40.8 bits (94),  Expect = 1e-06
 Identities = 20/58 (34%), Positives = 36/58 (62%), Gaps = 4/58 (7%)

Query  19   IAIIGSGMAGLATARILKDAGHAITIFEALPGRG----MDSHSIEFEGGVIDAPLRVM  72
            +AI+GSG AGLA+A  L  AGH++T+FE     G        +++ E G+++  ++++
Sbjct  155  VAIVGSGPAGLASADQLNQAGHSVTVFERADRAGGLLTYGIPNMKLEKGIVERRIKLL  212


>Q5HCY9 4,4'-diapophytoene desaturase (4,4'-diaponeurosporene-forming) 
[Staphylococcus aureus (strain COL)]
Length=502

 Score = 40.8 bits (94),  Expect = 1e-06
 Identities = 23/67 (34%), Positives = 37/67 (55%), Gaps = 1/67 (1%)

Query  17  LDIAIIGSGMAGLATARILKDAGHAITIFEALPGRGMDSHSIEFEGGVID-APLRVMNPF  75
           + IA+IG+G+ GLA A  +   GH +TIFE     G   + ++ +G   D  P  VM P 
Sbjct  1   MKIAVIGAGVTGLAAAARIASQGHEVTIFEKNNNVGGCMNQLKKDGFTFDMGPTIVMMPD  60

Query  76  LWKNTLS  82
           ++K+  +
Sbjct  61  VYKDVFT  67


>B5U6Y8 L-amino-acid oxidase [Echis ocellatus]
Length=504

 Score = 40.8 bits (94),  Expect = 1e-06
 Identities = 22/57 (39%), Positives = 35/57 (61%), Gaps = 3/57 (5%)

Query  18   DIAIIGSGMAGLATARILKDAGHAITIFEA--LPGRGMDSHSIEFEGGVID-APLRV  71
            DI ++G+GM+GL+ A +L  AGH +T+ EA  L G  + +H    EG   +  P+R+
Sbjct  53   DIVVVGAGMSGLSAAYVLAGAGHKVTVLEASQLVGGRVRTHRNAKEGWYANLGPMRI  109


>P86810 L-amino-acid oxidase [Siganus canaliculatus]
Length=527

 Score = 40.8 bits (94),  Expect = 1e-06
 Identities = 16/29 (55%), Positives = 24/29 (83%), Gaps = 0/29 (0%)

Query  19  IAIIGSGMAGLATARILKDAGHAITIFEA  47
           + I+G+G+AGL  A++L+DAGH +TI EA
Sbjct  63  VVIVGAGVAGLTAAKLLQDAGHRVTIVEA  91


>Q8CIG3 Lysine-specific histone demethylase 1B [Mus musculus]
Length=826

 Score = 40.8 bits (94),  Expect = 1e-06
 Identities = 59/266 (22%), Positives = 108/266 (41%), Gaps = 34/266 (13%)

Query  19   IAIIGSGMAGLATARILKDAGHAITIFEA---LPGRGMDSHSIEFEGGVIDAPLRVMNPF  75
            + ++G+G AGLA AR L + G  +T+ EA   + GR  D  S  F+G V+    +++N  
Sbjct  391  VLVVGAGPAGLAAARQLHNFGMKVTVLEAKDRIGGRVWDDKS--FKGVVVGRGPQIVNGC  448

Query  76   LWKNTLSLATHLGMTMFPVRTYMACSWLFEDRTETWLTTTRSRIGNFPIINNRKGLKQYG  135
            +      +   LG++M  +     C  + E    T  T  +    +F  + +        
Sbjct  449  INNPVALMCEQLGISMRKLGE--RCDLIQEGGRITDPTVDKRMDFHFNALLDVVS----E  502

Query  136  WRLVKGMLQ---LKTAIHQFFKSKNQDITLAEFINQNDIEEVFWHGAVMPV----LYTVC  188
            WR  K +LQ   L   I + +++         F+ ++ I+     G V+      L   C
Sbjct  503  WRKDKTLLQDVPLGEKIEEIYRA---------FVKESGIQFSELEGQVLQFHLSNLEYAC  553

Query  189  --TCNPKTIGDWPAKPLLVFLRQLTDGDALLRMHGGTPAFVDRLIDGIHIHSGSAIVKVE  246
              + +  +   W       F  Q      LL    G    +++L +G+ I   S +  ++
Sbjct  554  GSSLHQVSARSWDHNE---FFAQFAGDHTLLT--PGYSTIIEKLAEGLDIRLKSPVQSID  608

Query  247  QQGDKVLVENALGEQNLFDRVVIATP  272
              GD+V V    G  +   +V++  P
Sbjct  609  YTGDEVQVTTTDGMGHSAQKVLVTVP  634


>Q8MP06 Senecionine N-oxygenase [Tyria jacobaeae]
Length=456

 Score = 40.4 bits (93),  Expect = 1e-06
 Identities = 20/34 (59%), Positives = 24/34 (71%), Gaps = 0/34 (0%)

Query  19  IAIIGSGMAGLATARILKDAGHAITIFEALPGRG  52
           + IIG+G +GLATAR L+D G   TIFEA P  G
Sbjct  28  VCIIGAGYSGLATARYLQDYGLNYTIFEATPNIG  61


>Q96RQ9 L-amino-acid oxidase [Homo sapiens]
Length=567

 Score = 40.4 bits (93),  Expect = 1e-06
 Identities = 15/29 (52%), Positives = 23/29 (79%), Gaps = 0/29 (0%)

Query  19  IAIIGSGMAGLATARILKDAGHAITIFEA  47
           + ++G+G+AGL  A++L DAGH +TI EA
Sbjct  62  VIVVGAGVAGLVAAKVLSDAGHKVTILEA  90


>Q48MT7 Renalase [Pseudomonas savastanoi pv. phaseolicola (strain 
1448A / Race 6)]
Length=328

 Score = 40.0 bits (92),  Expect = 1e-06
 Identities = 20/48 (42%), Positives = 29/48 (60%), Gaps = 0/48 (0%)

Query  19  IAIIGSGMAGLATARILKDAGHAITIFEALPGRGMDSHSIEFEGGVID  66
           IAIIG+G+AGL+ A+ L  AGH + +F+   G G    S   + G +D
Sbjct  5   IAIIGTGIAGLSAAQALTSAGHQVHLFDKSRGSGGRMSSKRSDAGSLD  52


 Score = 19.2 bits (38),  Expect = 5.3
 Identities = 5/16 (31%), Positives = 8/16 (50%), Gaps = 0/16 (0%)

Query  394  DPERKVFYCGSWSCDG  409
            D +  ++ CG W   G
Sbjct  292  DADLGIYVCGDWCLSG  307



Lambda      K        H        a         alpha
   0.324    0.139    0.432    0.792     4.96 

Gapped
Lambda      K        H        a         alpha    sigma
   0.267   0.0410    0.140     1.90     42.6     43.6 

Effective search space used: 3371720


  Database: 2e2b093ba645ced97e24a599ae90bc7f.SwissProt.fasta
    Posted date:  May 30, 2024  1:07 AM
  Number of letters in database: 9,508
  Number of sequences in database:  18



Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Neighboring words threshold: 11
Window for multiple hits: 40