BLASTP 2.12.0+
Reference: Stephen F. Altschul, Thomas L. Madden, Alejandro A.
Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J.
Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of
protein database search programs", Nucleic Acids Res. 25:3389-3402.
Reference for composition-based statistics: Alejandro A. Schaffer,
L. Aravind, Thomas L. Madden, Sergei Shavirin, John L. Spouge, Yuri
I. Wolf, Eugene V. Koonin, and Stephen F. Altschul (2001),
"Improving the accuracy of PSI-BLAST protein database searches with
composition-based statistics and other refinements", Nucleic Acids
Res. 29:2994-3005.
Database: d12d048d45c3ecc5aff3ed9344dded80.SwissProt.fasta
11 sequences; 4,783 total letters
Query= ACIAD3382
Length=428
Score E
Sequences producing significant alignments: (Bits) Value
Q9WZY4 O-acetyl-L-homoserine sulfhydrylase [Thermotoga maritima (... 464 7e-166
Q5SK88 O-acetyl-L-homoserine sulfhydrylase 1 [Thermus thermophilu... 452 1e-161
P94890 O-acetyl-L-homoserine sulfhydrylase [Leptospira meyeri] 453 2e-161
O13326 Homocysteine synthase [Schizosaccharomyces pombe (strain 9... 441 6e-157
P50125 Homocysteine synthase [Emericella nidulans (strain FGSC A4... 438 1e-155
A0A0D2YG02 Sulfhydrylase FUB7 [Fusarium oxysporum f. sp. lycopers... 434 5e-154
S0DUX5 Sulfhydrylase FUB7 [Gibberella fujikuroi (strain CBS 195.3... 432 2e-153
W7MS09 Sulfhydrylase FUB7 [Gibberella moniliformis (strain M3125 ... 430 1e-152
Q92441 Homocysteine/cysteine synthase [Kluyveromyces lactis (stra... 424 5e-150
P06106 Homocysteine/cysteine synthase [Saccharomyces cerevisiae (... 421 1e-148
Q79VI4 O-acetyl-L-homoserine sulfhydrylase [Corynebacterium gluta... 370 8e-129
>Q9WZY4 O-acetyl-L-homoserine sulfhydrylase [Thermotoga maritima
(strain ATCC 43589 / DSM 3109 / JCM 10099 / NBRC 100826 /
MSB8)]
Length=430
Score = 464 bits (1193), Expect = 7e-166
Identities = 242/425 (57%), Positives = 308/425 (72%), Gaps = 9/425 (2%)
Query 4 RYKDETLAIHAGYSP-EPTTKAVAVPIYQTTSYAFDNTQHGADLFDLKVQGNIYTRIMNP 62
+Y T A+HAGY P E T + AVPIYQTTSY F ++ H A LF L+ G IYTRI NP
Sbjct 5 KYGYNTRALHAGYEPPEQATGSRAVPIYQTTSYVFRDSDHAARLFALEEPGFIYTRIGNP 64
Query 63 TTAVLEQRLAALEGGIGALALASGMAAITYAIQTITEAGDNIASVSTLYGGTYNLFAHTL 122
T +VLE+R+AALE G+GALA+ASG AAITYAI I GD I S S LYGGTYNLF HTL
Sbjct 65 TVSVLEERIAALEEGVGALAVASGQAAITYAILNIAGPGDEIVSGSALYGGTYNLFRHTL 124
Query 123 -PKQGIEVRFFDDQQPEQLRSLIDDKTKLVFVESIGNPLGNIIDLETIAKIAHEYGVPVV 181
K GI V+F D+ P+ + I +KTK V++E+IGNP + D E IA+IAH +GVP++
Sbjct 125 YKKSGIIVKFVDETDPKNIEEAITEKTKAVYLETIGNPGLTVPDFEAIAEIAHRHGVPLI 184
Query 182 VDNTVATPVLQKSFDFGADIIVHSLTKYIGGHGNSIGGIIVDSGKFPW--GKYPERFKVL 239
VDNTVA P + + F+ GADI+V+S TK+IGGHG SIGG+IVDSGKF W GK+PE L
Sbjct 185 VDNTVA-PYIFRPFEHGADIVVYSATKFIGGHGTSIGGLIVDSGKFDWTNGKFPE----L 239
Query 240 NTPDPSYHGVNYVEALGEAAFIGRARVVPLRNTGAAISPLSVFLILQGLETLSLRIERHT 299
PDPSYHGV+YVE EAA+I + R LR+ G+ +SP + FL + GLETLSLR+++H
Sbjct 240 VEPDPSYHGVSYVETFKEAAYIAKCRTQLLRDLGSCMSPFNAFLFILGLETLSLRMKKHC 299
Query 300 ENALQVAEYLKQHPKVKWVNYAGLKDHPQHDLAQKYVKGKPSAILTFGVQDGREGGTRFI 359
ENAL++ E+LK HP V WVNY + + + A KY+K AI+TFGV+ G+E G +FI
Sbjct 300 ENALKIVEFLKSHPAVSWVNYPIAEGNKTRENALKYLKEGYGAIVTFGVKGGKEAGKKFI 359
Query 360 DALQLFTRLVNIGDAKSLACHPATTTHRQLNAEELKAAGVSEDMVRLSVGIEHIDDLIAD 419
D+L L + L NIGDA++LA HPA+TTH+QL EE GV+ DM+RLSVGIE ++D+IAD
Sbjct 360 DSLTLISHLANIGDARTLAIHPASTTHQQLTEEEQLKTGVTPDMIRLSVGIEDVEDIIAD 419
Query 420 LEQAL 424
L+QAL
Sbjct 420 LDQAL 424
>Q5SK88 O-acetyl-L-homoserine sulfhydrylase 1 [Thermus thermophilus
(strain ATCC 27634 / DSM 579 / HB8)]
Length=421
Score = 452 bits (1164), Expect = 1e-161
Identities = 235/422 (56%), Positives = 296/422 (70%), Gaps = 8/422 (2%)
Query 8 ETLAIHAGYSPEPTTKAVAVPIYQTTSYAFDNTQHGADLFDLKVQGNIYTRIMNPTTAVL 67
ETL +HAGY PEPTT + VPIY TTSY F + +H A+LF LK GNIY+RIMNPT VL
Sbjct 4 ETLQLHAGYEPEPTTLSRQVPIYPTTSYVFKSPEHAANLFALKEFGNIYSRIMNPTVDVL 63
Query 68 EQRLAALEGGIGALALASGMAAITYAIQTITEAGDNIASVSTLYGGTYNLFAHTLPKQGI 127
E+RLAALEGG ALA ASG AA A+ T+ +AGDNI S LYGGT+N F TL + GI
Sbjct 64 EKRLAALEGGKAALATASGHAAQFLALTTLAQAGDNIVSTPNLYGGTFNQFKVTLKRLGI 123
Query 128 EVRFFD-DQQPEQLRSLIDDKTKLVFVESIGNPLGNIIDLETIAKIAHEYGVPVVVDNTV 186
EVRF +++PE+ +L D+KT+ +VESIGNP NI DLE +A+ A E GV ++VDNT
Sbjct 124 EVRFTSREERPEEFLALTDEKTRAWWVESIGNPALNIPDLEALAQAAREKGVALIVDNTF 183
Query 187 ATP-VLQKSFDFGADIIVHSLTKYIGGHGNSIGGIIVDSGKFPW--GKYPERFKVLNTPD 243
L + +GA ++ HSLTK++GGHG I G IVD G FPW G+YP +L P
Sbjct 184 GMGGYLLRPLAWGAALVTHSLTKWVGGHGAVIAGAIVDGGNFPWEGGRYP----LLTEPQ 239
Query 244 PSYHGVNYVEALGEAAFIGRARVVPLRNTGAAISPLSVFLILQGLETLSLRIERHTENAL 303
P YHG+ EA GE AFI +ARV LR+ G A+ P +++L G+ETLSLR ERH EN L
Sbjct 240 PGYHGLRLTEAFGELAFIVKARVDGLRDQGQALGPFEAWVVLLGMETLSLRAERHVENTL 299
Query 304 QVAEYLKQHPKVKWVNYAGLKDHPQHDLAQKYVKGKPSAILTFGVQDGREGGTRFIDALQ 363
+A +L + P+V WVNY GL HP HD AQKY KGKP A+LTFG++ G E RFI L+
Sbjct 300 HLAHWLLEQPQVAWVNYPGLPHHPHHDRAQKYFKGKPGAVLTFGLKGGYEAAKRFISRLK 359
Query 364 LFTRLVNIGDAKSLACHPATTTHRQLNAEELKAAGVSEDMVRLSVGIEHIDDLIADLEQA 423
L + L N+GD ++LA HPA+TTH QL+ EE AGVS +MVRLSVG+EH++DL A+L++A
Sbjct 360 LISHLANVGDTRTLAIHPASTTHSQLSPEEQAQAGVSPEMVRLSVGLEHVEDLKAELKEA 419
Query 424 LA 425
LA
Sbjct 420 LA 421
>P94890 O-acetyl-L-homoserine sulfhydrylase [Leptospira meyeri]
Length=442
Score = 453 bits (1165), Expect = 2e-161
Identities = 230/436 (53%), Positives = 303/436 (69%), Gaps = 11/436 (3%)
Query 1 MTHRYKDETLAIHAGYSPEPTTKAVAVPIYQTTSYAFDNTQHGADLFDLKVQGNIYTRIM 60
M +K ET+A+H G P+PTT + AVP+YQTTSY F +T H A LF L+ GNIYTR+M
Sbjct 9 MPRNFKPETIALHGGQEPDPTTTSRAVPLYQTTSYVFKDTDHAARLFGLQEFGNIYTRLM 68
Query 61 NPTTAVLEQRLAALEGGIGALALASGMAAITYAIQTITEAGDNIASVSTLYGGTYNLFAH 120
NPTT VLE+R+AALEGG+ ALA ASG +A A+ I EAG I + S+LYGGTYNL +
Sbjct 69 NPTTDVLEKRVAALEGGVAALATASGQSAEMLALLNIVEAGQEIVASSSLYGGTYNLLHY 128
Query 121 TLPKQGIEVRFFDDQQPEQLRSLIDDKTKLVFVESIGNPLGNIIDLETIAKIAHEYGVPV 180
T PK GI+V F D PE R +DKT+ + E++GNP + +D+ ++K+A E GVP+
Sbjct 129 TFPKLGIKVHFVDQSDPENFRKASNDKTRAFYAETLGNPKLDTLDIAAVSKVAKEVGVPL 188
Query 181 VVDNTVATPVLQKSFDFGADIIVHSLTKYIGGHGNSIGGIIVDSGKFPWGKYPERFKVLN 240
V+DNT+ +P L GADI+VHSLTK++GGHG SIGGII+D G F WG +FK
Sbjct 189 VIDNTMPSPYLVNPLKHGADIVVHSLTKFLGGHGTSIGGIIIDGGSFNWGN--GKFKNFT 246
Query 241 TPDPSYHGVNYVEALGE--------AAFIGRARVVPLRNTGAAISPLSVFLILQGLETLS 292
PDPSYHG+ + E G+ AFI +ARV LR+ G AISP + + ILQG+ETL
Sbjct 247 EPDPSYHGLKFWEVFGKFEPFGGVNIAFILKARVQGLRDLGPAISPFNAWQILQGVETLP 306
Query 293 LRIERHTENALQVAEYLKQHPKVKWVNYAGLKDHPQHDLAQKY-VKGKPSAILTFGVQDG 351
LR+ERH+ NAL+VAE+L++HPK++WVNY GL + A+KY +G AI+ F ++ G
Sbjct 307 LRMERHSGNALKVAEFLQKHPKIEWVNYPGLSTDKNYATAKKYHERGLFGAIVGFEIKGG 366
Query 352 REGGTRFIDALQLFTRLVNIGDAKSLACHPATTTHRQLNAEELKAAGVSEDMVRLSVGIE 411
E +FID L+LF+ L NIGDAKSLA HPA+TTH+QL E +AGV+ VRLSVG+E
Sbjct 367 VEKAKKFIDGLELFSLLANIGDAKSLAIHPASTTHQQLTGPEQISAGVTPGFVRLSVGLE 426
Query 412 HIDDLIADLEQALATV 427
+IDD++ DLE+AL +
Sbjct 427 NIDDILVDLEEALKNI 442
>O13326 Homocysteine synthase [Schizosaccharomyces pombe (strain
972 / ATCC 24843)]
Length=429
Score = 441 bits (1134), Expect = 6e-157
Identities = 219/418 (52%), Positives = 289/418 (69%), Gaps = 1/418 (0%)
Query 8 ETLAIHAGYSPEPTTKAVAVPIYQTTSYAFDNTQHGADLFDLKVQGNIYTRIMNPTTAVL 67
ETL +HAG P+ T + AVPIY TTSY F + HG LF L+ G IY+R+MNPT V
Sbjct 9 ETLQLHAGQEPDAATSSRAVPIYATTSYVFRDCDHGGRLFGLQEPGYIYSRMMNPTADVF 68
Query 68 EQRLAALEGGIGALALASGMAAITYAIQTITEAGDNIASVSTLYGGTYNLFAHTLPKQGI 127
E+R+AALE G A+A +SG +A+ A+ T+ +AGDNI S S LYGGTYNLF TLP+ GI
Sbjct 69 EKRIAALEHGAAAIATSSGTSALFMALTTLAKAGDNIVSTSYLYGGTYNLFKVTLPRLGI 128
Query 128 EVRFFDDQQPEQLRSLIDDKTKLVFVESIGNPLGNIIDLETIAKIAHEYGVPVVVDNTVA 187
+F + P L + ID+ TK V+VESIGNP+ N+ D E IA++AH GVP++VDNT
Sbjct 129 TTKFVNGDDPNDLAAQIDENTKAVYVESIGNPMYNVPDFERIAEVAHAAGVPLMVDNTFG 188
Query 188 TP-VLQKSFDFGADIIVHSLTKYIGGHGNSIGGIIVDSGKFPWGKYPERFKVLNTPDPSY 246
L + D GADI+ HS TK+IGGHG +IGG+IVDSGKF W K +RF N P P Y
Sbjct 189 GGGYLVRPIDHGADIVTHSATKWIGGHGTTIGGVIVDSGKFDWKKNSKRFPEFNEPHPGY 248
Query 247 HGVNYVEALGEAAFIGRARVVPLRNTGAAISPLSVFLILQGLETLSLRIERHTENALQVA 306
HG+ + E G A+ R LR+ G +P VFL+LQGLETLSLR+ERH +NA +A
Sbjct 249 HGMVFTETFGNLAYAFACRTQTLRDVGGNANPFGVFLLLQGLETLSLRMERHVQNAFALA 308
Query 307 EYLKQHPKVKWVNYAGLKDHPQHDLAQKYVKGKPSAILTFGVQDGREGGTRFIDALQLFT 366
+YL++HPKV WV+Y GL+ H H LA+KY+K A+L+FG + G + + ++AL+L +
Sbjct 309 KYLEKHPKVNWVSYPGLESHVSHKLAKKYLKNGYGAVLSFGAKGGPDQSRKVVNALKLAS 368
Query 367 RLVNIGDAKSLACHPATTTHRQLNAEELKAAGVSEDMVRLSVGIEHIDDLIADLEQAL 424
+L N+GDAK+L PA TTH QL EE +AGV++D++R++VGIEHIDD+IAD QAL
Sbjct 369 QLANVGDAKTLVIAPAYTTHLQLTDEEQISAGVTKDLIRVAVGIEHIDDIIADFAQAL 426
>P50125 Homocysteine synthase [Emericella nidulans (strain FGSC
A4 / ATCC 38163 / CBS 112.46 / NRRL 194 / M139)]
Length=437
Score = 438 bits (1126), Expect = 1e-155
Identities = 217/419 (52%), Positives = 288/419 (69%), Gaps = 1/419 (0%)
Query 8 ETLAIHAGYSPEPTTKAVAVPIYQTTSYAFDNTQHGADLFDLKVQGNIYTRIMNPTTAVL 67
ETL +HAG P+P T + AVPIY TTSY F+++ HGA LF LK GNIY+RIMNPT V
Sbjct 10 ETLQLHAGQEPDPATNSRAVPIYATTSYTFNDSAHGARLFGLKEFGNIYSRIMNPTVDVF 69
Query 68 EQRLAALEGGIGALALASGMAAITYAIQTITEAGDNIASVSTLYGGTYNLFAHTLPKQGI 127
E+R+AALEGG+ A+A +SG AA AI + AGDNI S S LYGGTYN F P+ GI
Sbjct 70 EKRIAALEGGVAAVAASSGQAAQFMAISALAHAGDNIVSTSNLYGGTYNQFKVLFPRLGI 129
Query 128 EVRFFDDQQPEQLRSLIDDKTKLVFVESIGNPLGNIIDLETIAKIAHEYGVPVVVDNTV- 186
+F + E + + IDD+TK V+VE+IGNP N+ D E IAK+AHE G+P+VVDNT
Sbjct 130 TTKFVQGDKAEDIAAAIDDRTKAVYVETIGNPRYNVPDFEVIAKVAHEKGIPLVVDNTFG 189
Query 187 ATPVLQKSFDFGADIIVHSLTKYIGGHGNSIGGIIVDSGKFPWGKYPERFKVLNTPDPSY 246
A + + GADI+VHS TK+IGGHG +IGG++VDSGKF WGK RF P Y
Sbjct 190 AGGYFVRPIEHGADIVVHSATKWIGGHGTTIGGVVVDSGKFDWGKNAARFPQFTQPSEGY 249
Query 247 HGVNYVEALGEAAFIGRARVVPLRNTGAAISPLSVFLILQGLETLSLRIERHTENALQVA 306
HG+N+ E G AF R RV LR+ G+A++P + ++ GLETLSLR ERH NAL +A
Sbjct 250 HGLNFWETFGPIAFAIRVRVEILRDLGSALNPFAAQQLILGLETLSLRAERHASNALALA 309
Query 307 EYLKQHPKVKWVNYAGLKDHPQHDLAQKYVKGKPSAILTFGVQDGREGGTRFIDALQLFT 366
+LK++ V WV+Y GL++H H++A+KY+K +L+FGV+ G++ +D +L +
Sbjct 310 NWLKKNDHVSWVSYVGLEEHSSHEVAKKYLKRGFGGVLSFGVKGEAAVGSQVVDNFKLIS 369
Query 367 RLVNIGDAKSLACHPATTTHRQLNAEELKAAGVSEDMVRLSVGIEHIDDLIADLEQALA 425
L N+GD+K+LA HP +TTH QL +E +GV+ED +R+SVG EHIDD+IAD EQ+ A
Sbjct 370 NLANVGDSKTLAIHPWSTTHEQLTDQERIDSGVTEDAIRISVGTEHIDDIIADFEQSFA 428
>A0A0D2YG02 Sulfhydrylase FUB7 [Fusarium oxysporum f. sp. lycopersici
(strain 4287 / CBS 123668 / FGSC 9935 / NRRL 34936)]
Length=433
Score = 434 bits (1115), Expect = 5e-154
Identities = 217/417 (52%), Positives = 292/417 (70%), Gaps = 1/417 (0%)
Query 8 ETLAIHAGYSPEPTTKAVAVPIYQTTSYAFDNTQHGADLFDLKVQGNIYTRIMNPTTAVL 67
ETL +HAGY+P+P T++ AVPIY T+SY F+++ HGA LF LK GNIY+R+MNPT V
Sbjct 10 ETLQLHAGYTPDPHTRSTAVPIYATSSYTFNDSAHGARLFGLKELGNIYSRLMNPTVDVF 69
Query 68 EQRLAALEGGIGALALASGMAAITYAIQTITEAGDNIASVSTLYGGTYNLFAHTLPKQGI 127
E+R+AALEGGI A A +SG AA I T+ +AGDNI + S LYGGTYN LP+ GI
Sbjct 70 EKRIAALEGGIAAAATSSGQAAQFLTIATLAKAGDNIVASSHLYGGTYNQLNVLLPRFGI 129
Query 128 EVRFFDDQQPEQLRSLIDDKTKLVFVESIGNPLGNIIDLETIAKIAHEYGVPVVVDNTV- 186
+ +F + E + IDD+T+ ++VES+ NP + D E IAKIAHE+G+P+VVDNT+
Sbjct 130 KTKFVRSGKLEDYAAAIDDQTRAIYVESMSNPDYVVPDFEGIAKIAHEHGIPLVVDNTLG 189
Query 187 ATPVLQKSFDFGADIIVHSLTKYIGGHGNSIGGIIVDSGKFPWGKYPERFKVLNTPDPSY 246
A + + GADI+VHS TK+IGGHG +IGG+IVDSG+F W K+ ERF + P PSY
Sbjct 190 AGGYYIRPIEHGADIVVHSATKWIGGHGTTIGGVIVDSGRFNWNKHSERFPEMVEPSPSY 249
Query 247 HGVNYVEALGEAAFIGRARVVPLRNTGAAISPLSVFLILQGLETLSLRIERHTENALQVA 306
HG+ Y EA G A FI R RV LR+ GA +SP S +L G+ETL LR ERH +N ++A
Sbjct 250 HGLKYWEAFGPATFITRIRVEMLRDIGACLSPFSAQQLLLGIETLGLRAERHAQNTEKLA 309
Query 307 EYLKQHPKVKWVNYAGLKDHPQHDLAQKYVKGKPSAILTFGVQDGREGGTRFIDALQLFT 366
+Y + P V WV + G + HP + A+KY+ A+L+ GV+ G++ +D L+L +
Sbjct 310 KYFESSPNVSWVLWPGSESHPTYAQAKKYLTRGFGAMLSIGVKGDASAGSKVVDGLKLVS 369
Query 367 RLVNIGDAKSLACHPATTTHRQLNAEELKAAGVSEDMVRLSVGIEHIDDLIADLEQA 423
L N+GDAKSLA HP +TTH QL+ +E A+GV+EDM+R+SVGIEH+DD+IAD EQ+
Sbjct 370 NLANVGDAKSLAIHPWSTTHEQLSEDERLASGVTEDMIRISVGIEHVDDIIADFEQS 426
>S0DUX5 Sulfhydrylase FUB7 [Gibberella fujikuroi (strain CBS 195.34
/ IMI 58289 / NRRL A-6831)]
Length=433
Score = 432 bits (1111), Expect = 2e-153
Identities = 215/417 (52%), Positives = 292/417 (70%), Gaps = 1/417 (0%)
Query 8 ETLAIHAGYSPEPTTKAVAVPIYQTTSYAFDNTQHGADLFDLKVQGNIYTRIMNPTTAVL 67
ETL +HAGY+P+P T++ AVPIY T+SY F+++ HGA LF LK GNIY+R+MNPT V
Sbjct 10 ETLQLHAGYTPDPHTRSTAVPIYATSSYTFNDSAHGARLFGLKELGNIYSRLMNPTVDVF 69
Query 68 EQRLAALEGGIGALALASGMAAITYAIQTITEAGDNIASVSTLYGGTYNLFAHTLPKQGI 127
E+R+AALEGGI A A +SG AA I T+ +AGDNI + S LYGGTYN LP+ GI
Sbjct 70 EKRIAALEGGIAAAATSSGQAAQFLTIATLAKAGDNIVASSHLYGGTYNQLNVLLPRFGI 129
Query 128 EVRFFDDQQPEQLRSLIDDKTKLVFVESIGNPLGNIIDLETIAKIAHEYGVPVVVDNTV- 186
+ +F + E + IDD+T+ ++VES+ NP + D E IAKIAHE+G+P+VVDNT+
Sbjct 130 KTKFVRSGKLEDYAAAIDDQTRAIYVESMSNPDYVVPDFEGIAKIAHEHGIPLVVDNTLG 189
Query 187 ATPVLQKSFDFGADIIVHSLTKYIGGHGNSIGGIIVDSGKFPWGKYPERFKVLNTPDPSY 246
A + + GADI+VHS TK+IGGHG +IGG+IVDSG+F W K+ +RF + P PSY
Sbjct 190 AGGYYIRPIEHGADIVVHSATKWIGGHGTTIGGVIVDSGRFNWNKHSDRFPEMVEPSPSY 249
Query 247 HGVNYVEALGEAAFIGRARVVPLRNTGAAISPLSVFLILQGLETLSLRIERHTENALQVA 306
HG+ Y EA G A FI R RV LR+ GA +SP S +L G+ETL LR ERH +N +++
Sbjct 250 HGLKYWEAFGPATFITRIRVEMLRDIGACLSPFSAQQLLLGIETLGLRAERHAQNTEKLS 309
Query 307 EYLKQHPKVKWVNYAGLKDHPQHDLAQKYVKGKPSAILTFGVQDGREGGTRFIDALQLFT 366
+Y + P V WV + G + HP + A+KY+ A+L+ GV+ G++ +D L+L +
Sbjct 310 KYFESSPNVSWVLWPGSESHPTYSQAKKYLTRGFGAMLSIGVKGDASAGSKVVDGLKLVS 369
Query 367 RLVNIGDAKSLACHPATTTHRQLNAEELKAAGVSEDMVRLSVGIEHIDDLIADLEQA 423
L N+GDAKSLA HP +TTH QL+ +E A+GV+EDM+R+SVGIEH+DD+IAD EQ+
Sbjct 370 NLANVGDAKSLAIHPWSTTHEQLSEDERLASGVTEDMIRISVGIEHVDDIIADFEQS 426
>W7MS09 Sulfhydrylase FUB7 [Gibberella moniliformis (strain M3125
/ FGSC 7600)]
Length=433
Score = 430 bits (1106), Expect = 1e-152
Identities = 215/417 (52%), Positives = 291/417 (70%), Gaps = 1/417 (0%)
Query 8 ETLAIHAGYSPEPTTKAVAVPIYQTTSYAFDNTQHGADLFDLKVQGNIYTRIMNPTTAVL 67
ETL +HAGY+P+P T++ AVPIY T+SY F+++ HGA LF LK GNIY+R+MNPT V
Sbjct 10 ETLQLHAGYTPDPHTRSTAVPIYATSSYTFNDSAHGARLFGLKELGNIYSRLMNPTVDVF 69
Query 68 EQRLAALEGGIGALALASGMAAITYAIQTITEAGDNIASVSTLYGGTYNLFAHTLPKQGI 127
E+R+AALEGGI A A +SG AA I T+ +AGDNI + S LYGGTYN P+ GI
Sbjct 70 EKRIAALEGGIAAAATSSGQAAQFLTIATLAKAGDNIVASSHLYGGTYNQLNVLFPRFGI 129
Query 128 EVRFFDDQQPEQLRSLIDDKTKLVFVESIGNPLGNIIDLETIAKIAHEYGVPVVVDNTV- 186
+ +F + E + IDD+T+ ++VES+ NP + D E IAKIAHE+G+P+VVDNT+
Sbjct 130 KTKFVRSGKLEDYVAAIDDQTRAIYVESMSNPDYVVPDFEGIAKIAHEHGIPLVVDNTLG 189
Query 187 ATPVLQKSFDFGADIIVHSLTKYIGGHGNSIGGIIVDSGKFPWGKYPERFKVLNTPDPSY 246
A + + GADI+VHS TK+IGGHG +IGG+IVDSG+F W K+ +RF + P PSY
Sbjct 190 AGGYYIRPIEHGADIVVHSATKWIGGHGTTIGGVIVDSGRFNWNKHSDRFPEMVEPSPSY 249
Query 247 HGVNYVEALGEAAFIGRARVVPLRNTGAAISPLSVFLILQGLETLSLRIERHTENALQVA 306
HG+ Y EA G A FI R RV LR+ GA +SP S +L G+ETL LR ERH +N ++A
Sbjct 250 HGLKYWEAFGPATFITRIRVEMLRDIGACLSPFSAQQLLLGIETLGLRAERHAQNTEKLA 309
Query 307 EYLKQHPKVKWVNYAGLKDHPQHDLAQKYVKGKPSAILTFGVQDGREGGTRFIDALQLFT 366
+Y + P V WV + G + HP + A+KY+ A+L+ GV+ G++ +D L+L +
Sbjct 310 KYFESSPNVSWVLWPGSESHPTYAQAKKYLTRGFGAMLSIGVKGDASAGSKVVDGLKLVS 369
Query 367 RLVNIGDAKSLACHPATTTHRQLNAEELKAAGVSEDMVRLSVGIEHIDDLIADLEQA 423
L N+GDAKSLA HP +TTH QL+ +E A+GV+EDM+R+SVGIEH+DD+IAD EQ+
Sbjct 370 NLANVGDAKSLAIHPWSTTHEQLSEDERLASGVTEDMIRISVGIEHVDDIIADFEQS 426
>Q92441 Homocysteine/cysteine synthase [Kluyveromyces lactis (strain
ATCC 8585 / CBS 2359 / DSM 70799 / NBRC 1267 / NRRL Y-1140
/ WM37)]
Length=444
Score = 424 bits (1090), Expect = 5e-150
Identities = 221/434 (51%), Positives = 290/434 (67%), Gaps = 16/434 (4%)
Query 8 ETLAIHAGYSPEPTTKAV---AVPIYQTTSYAFDNTQHGADLFDLKVQGNIYTRIMNPTT 64
+TL +HAG E T A AVPIY TTSY F++++HGA LF L+ G IY+RIMNPT
Sbjct 6 DTLQLHAGQ--EKTADAHNPRAVPIYATTSYVFNDSKHGAQLFGLETPGYIYSRIMNPTL 63
Query 65 AVLEQRLAALEGGIGALALASGMAAITYAIQTITEAGDNIASVSTLYGGTYNLFAHTLPK 124
VLE+RLAALEGGI ALA +SG AA T A+ + GDNI S S LYGGTYN F +
Sbjct 64 DVLEKRLAALEGGIAALATSSGQAAQTLAVTGLAHTGDNIVSTSFLYGGTYNQFKVAFKR 123
Query 125 QGIEVRFFDDQQPEQLRSLIDDKTKLVFVESIGNPLGNIIDLETIAKIAHEYGVPVVVDN 184
GIE RF D +PE L D+KTK +++ESIGNP N+ D E I +AH++G+PVVVDN
Sbjct 124 LGIEARFVDGDKPEDFEKLFDEKTKALYLESIGNPKYNVPDFEKIVAVAHKHGIPVVVDN 183
Query 185 TV-ATPVLQKSFDFGADIIVHSLTKYIGGHGNSIGGIIVDSGKFPWGKYPERFKVLNTPD 243
T A + +GADI+ HS TK+IGGHG ++GG+I+DSGKFPW YPE+F + P
Sbjct 184 TFGAGGFFCQPIKYGADIVTHSATKWIGGHGVTVGGVIIDSGKFPWKDYPEKFPQFSQPS 243
Query 244 PSYHGVNYVEALGEAAFIGRARVVPLRNTGAAISPLSVFLILQGLETLSLRIERHTENAL 303
YHG+ + +A G AAFIG R LR+ G +SP + FL+LQGLETLSLR ERH NAL
Sbjct 244 EGYHGLIFNDAFGPAAFIGHVRTELLRDLGPVLSPFAGFLLLQGLETLSLRGERHGSNAL 303
Query 304 QVAEYLKQHPKVKWVNYAGLKDHPQHDLAQKYVKGKPSAILTFGVQD----------GRE 353
++A+YL+ P V WV+Y GL H H+ A+KY++ +L+FGV+D +
Sbjct 304 KLAQYLESSPYVSWVSYPGLPSHSHHENAKKYLENGFGGVLSFGVKDLPNASEESDPFKA 363
Query 354 GGTRFIDALQLFTRLVNIGDAKSLACHPATTTHRQLNAEELKAAGVSEDMVRLSVGIEHI 413
G + +D L+L + L N+GD+K+L P TTH+QL EE A+GV++D++R+SVG E I
Sbjct 364 SGAQVVDNLKLASNLANVGDSKTLVIAPYFTTHQQLTDEEKLASGVTKDLIRVSVGTEFI 423
Query 414 DDLIADLEQALATV 427
DD+IAD E + ATV
Sbjct 424 DDIIADFEASFATV 437
>P06106 Homocysteine/cysteine synthase [Saccharomyces cerevisiae
(strain ATCC 204508 / S288c)]
Length=444
Score = 421 bits (1081), Expect = 1e-148
Identities = 215/433 (50%), Positives = 292/433 (67%), Gaps = 13/433 (3%)
Query 8 ETLAIHAGYSP--EPTTKAVAVPIYQTTSYAFDNTQHGADLFDLKVQGNIYTRIMNPTTA 65
+T+ +HAG + ++ AVPIY TTSY F+N++HG+ LF L+V G +Y+R NPT+
Sbjct 6 DTVQLHAGQENPGDNAHRSRAVPIYATTSYVFENSKHGSQLFGLEVPGYVYSRFQNPTSN 65
Query 66 VLEQRLAALEGGIGALALASGMAAITYAIQTITEAGDNIASVSTLYGGTYNLFAHTLPKQ 125
VLE+R+AALEGG ALA++SG AA T AIQ + GDNI S S LYGGTYN F + +
Sbjct 66 VLEERIAALEGGAAALAVSSGQAAQTLAIQGLAHTGDNIVSTSYLYGGTYNQFKISFKRF 125
Query 126 GIEVRFFDDQQPEQLRSLIDDKTKLVFVESIGNPLGNIIDLETIAKIAHEYGVPVVVDNT 185
GIE RF + PE+ + D++TK V++E+IGNP N+ D E I IAH++G+PVVVDNT
Sbjct 126 GIEARFVEGDNPEEFEKVFDERTKAVYLETIGNPKYNVPDFEKIVAIAHKHGIPVVVDNT 185
Query 186 V-ATPVLQKSFDFGADIIVHSLTKYIGGHGNSIGGIIVDSGKFPWGKYPERFKVLNTPDP 244
A + +GADI+ HS TK+IGGHG +IGGIIVDSGKFPW YPE+F + P
Sbjct 186 FGAGGYFCQPIKYGADIVTHSATKWIGGHGTTIGGIIVDSGKFPWKDYPEKFPQFSQPAE 245
Query 245 SYHGVNYVEALGEAAFIGRARVVPLRNTGAAISPLSVFLILQGLETLSLRIERHTENALQ 304
YHG Y EA G A+I R LR+ G ++P + FL+LQG+ETLSLR ERH ENAL+
Sbjct 246 GYHGTIYNEAYGNLAYIVHVRTELLRDLGPLMNPFASFLLLQGVETLSLRAERHGENALK 305
Query 305 VAEYLKQHPKVKWVNYAGLKDHPQHDLAQKYVKGKPSAILTFGVQD----------GREG 354
+A++L+Q P V WV+Y GL H H+ A+KY+ +L+FGV+D +
Sbjct 306 LAKWLEQSPYVSWVSYPGLASHSHHENAKKYLSNGFGGVLSFGVKDLPNADKETDPFKLS 365
Query 355 GTRFIDALQLFTRLVNIGDAKSLACHPATTTHRQLNAEELKAAGVSEDMVRLSVGIEHID 414
G + +D L+L + L N+GDAK+L P TTH+QLN +E A+GV++D++R+SVGIE ID
Sbjct 366 GAQVVDNLKLASNLANVGDAKTLVIAPYFTTHKQLNDKEKLASGVTKDLIRVSVGIEFID 425
Query 415 DLIADLEQALATV 427
D+IAD +Q+ TV
Sbjct 426 DIIADFQQSFETV 438
>Q79VI4 O-acetyl-L-homoserine sulfhydrylase [Corynebacterium glutamicum
(strain ATCC 13032 / DSM 20300 / BCRC 11384 / JCM
1318 / LMG 3730 / NCIMB 10025)]
Length=437
Score = 370 bits (949), Expect = 8e-129
Identities = 190/424 (45%), Positives = 275/424 (65%), Gaps = 5/424 (1%)
Query 8 ETLAIHAGYSPEPTTKAVAVPIYQTTSYAFDNTQHGADLFDLKVQGNIYTRIMNPTTAVL 67
ET +IHAG S + T A +PIYQ+T++ FD+ +H F L+ G +Y+R+ NPT L
Sbjct 15 ETRSIHAGQSVDAQTSARNLPIYQSTAFVFDSAEHAKQRFALEDLGPVYSRLTNPTVEAL 74
Query 68 EQRLAALEGGIGALALASGMAAITYAIQTITEAGDNIASVSTLYGGTYNLFAHTLPKQGI 127
E R+A+LEGG+ A+A +SG AA T AI + AGD+I + LYGGT LF TL + GI
Sbjct 75 ENRIASLEGGVHAVAFSSGQAATTNAILNLAGAGDHIVTSPRLYGGTETLFLITLNRLGI 134
Query 128 EVRFFDD-QQPEQLRSLIDDKTKLVFVESIGNPLGNIIDLETIAKIAHEYGVPVVVDNTV 186
+V F ++ PE ++ + TK F E+ NP +++D+ +A++AH VP+++DNT+
Sbjct 135 DVSFVENPDDPESWQAAVQPNTKAFFGETFANPQADVLDIPAVAEVAHRNSVPLIIDNTI 194
Query 187 ATPVLQKSFDFGADIIVHSLTKYIGGHGNSIGGIIVDSGKFPWGKYPER---FKVLNTPD 243
AT L + + GAD++V SLTK+ G+G+ +GG+++D GKF W + F TPD
Sbjct 195 ATAALVRPLELGADVVVASLTKFYTGNGSGLGGVLIDGGKFDWTVEKDGKPVFPYFVTPD 254
Query 244 PSYHGVNYVEALGEAAFIGRARVVPLRNTGAAISPLSVFLILQGLETLSLRIERHTENAL 303
+YHG+ Y + LG AF + RV LR+TG+ +S + + +QG++TLSLR+ERH ENA+
Sbjct 255 AAYHGLKYAD-LGAPAFGLKVRVGLLRDTGSTLSAFNAWAAVQGIDTLSLRLERHNENAI 313
Query 304 QVAEYLKQHPKVKWVNYAGLKDHPQHDLAQKYVKGKPSAILTFGVQDGREGGTRFIDALQ 363
+VAE+L H KV+ VN+AGLKD P + +K ++LTF ++ G++ FIDAL+
Sbjct 314 KVAEFLNNHEKVEKVNFAGLKDSPWYATKEKLGLKYTGSVLTFEIKGGKDEAWAFIDALK 373
Query 364 LFTRLVNIGDAKSLACHPATTTHRQLNAEELKAAGVSEDMVRLSVGIEHIDDLIADLEQA 423
L + L NIGD +SL HPATTTH Q + L AGV++ VRLSVGIE IDD+IADLE
Sbjct 374 LHSNLANIGDVRSLVVHPATTTHSQSDEAGLARAGVTQSTVRLSVGIETIDDIIADLEGG 433
Query 424 LATV 427
A +
Sbjct 434 FAAI 437
Lambda K H a alpha
0.319 0.137 0.396 0.792 4.96
Gapped
Lambda K H a alpha sigma
0.267 0.0410 0.140 1.90 42.6 43.6
Effective search space used: 1616900
Database: d12d048d45c3ecc5aff3ed9344dded80.SwissProt.fasta
Posted date: May 19, 2024 4:47 PM
Number of letters in database: 4,783
Number of sequences in database: 11
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Neighboring words threshold: 11
Window for multiple hits: 40
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Data ...
