BLASTP 2.12.0+
Reference: Stephen F. Altschul, Thomas L. Madden, Alejandro A.
Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J.
Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of
protein database search programs", Nucleic Acids Res. 25:3389-3402.
Reference for composition-based statistics: Alejandro A. Schaffer,
L. Aravind, Thomas L. Madden, Sergei Shavirin, John L. Spouge, Yuri
I. Wolf, Eugene V. Koonin, and Stephen F. Altschul (2001),
"Improving the accuracy of PSI-BLAST protein database searches with
composition-based statistics and other refinements", Nucleic Acids
Res. 29:2994-3005.
Database: 3bd51ba20115c9046080788ca1e1a0ff.SwissProt.fasta
18 sequences; 14,341 total letters
Query= ACIAD3361
Length=853
Score E
Sequences producing significant alignments: (Bits) Value
Q07806 Penicillin-insensitive transglycosylase / Penicillin-sensi... 669 0.0
P02918 Penicillin-insensitive transglycosylase / Penicillin-sensi... 565 0.0
Q87AW7 Penicillin-insensitive transglycosylase / Penicillin-sensi... 561 0.0
Q9PGD4 Penicillin-insensitive transglycosylase / Penicillin-sensi... 559 0.0
O87626 Penicillin-insensitive transglycosylase / Penicillin-sensi... 528 5e-179
Q9KNU5 Penicillin-insensitive transglycosylase / Penicillin-sensi... 528 6e-179
P0A0Z6 Penicillin-insensitive transglycosylase / Penicillin-sensi... 522 9e-177
P0A0Z5 Penicillin-insensitive transglycosylase / Penicillin-sensi... 522 9e-177
O86088 Penicillin-insensitive transglycosylase / Penicillin-sensi... 519 1e-175
O05131 Penicillin-insensitive transglycosylase / Penicillin-sensi... 519 1e-175
Q5FAC7 Penicillin-insensitive transglycosylase / Penicillin-sensi... 519 1e-175
O87579 Penicillin-insensitive transglycosylase / Penicillin-sensi... 518 3e-175
P31776 Penicillin-insensitive transglycosylase / Penicillin-sensi... 493 9e-165
P39793 Penicillin-insensitive transglycosylase / Penicillin-sensi... 176 3e-48
P38050 Penicillin-insensitive transglycosylase / Penicillin-sensi... 169 8e-47
P70997 Penicillin-insensitive transglycosylase / Penicillin-sensi... 167 3e-46
P02919 Penicillin-insensitive transglycosylase / Penicillin-sensi... 157 2e-42
P40750 Penicillin-insensitive transglycosylase / Penicillin-sensi... 151 3e-41
>Q07806 Penicillin-insensitive transglycosylase / Penicillin-sensitive
transpeptidase [Pseudomonas aeruginosa (strain ATCC
15692 / DSM 22644 / CIP 104116 / JCM 14847 / LMG 12228 / 1C
/ PRS 101 / PAO1)]
Length=822
Score = 669 bits (1727), Expect = 0.0
Identities = 354/748 (47%), Positives = 477/748 (64%), Gaps = 23/748 (3%)
Query 20 VLVSVPMGFYGMYLYIAPSLPEMSSLKKAPLLKPLQVYTSDNQLIAEYGGKLSVPVEYNQ 79
++ V + F G YLY++PSLP + +L+ L PL+VY+ D +LI+E+G P+ +
Sbjct 14 LICGVLLSFSGAYLYLSPSLPSVEALRNVQLQIPLKVYSEDGKLISEFGEMRRTPIRFAD 73
Query 80 IPPTFIHAFLAAEDSSFFEHSGISFKGLGRALSETVTGSNVQTGGSTITMQVAKNYYLSP 139
IP FIHA L+AED +F H G+ K L RA ++ + ++QTGGSTITMQVAKNY+L+
Sbjct 74 IPQDFIHALLSAEDDNFANHYGVDVKSLMRAAAQLLKSGHIQTGGSTITMQVAKNYFLTN 133
Query 140 ERTLKRKLTEIFLARKIEQNLTKQEILSLYVNKIFLGKNAYGIAAAAKIYYNKTLDQLSI 199
ER+ RK+ EI LA +IE+ LTK EIL LYVNKI+LG AYGI AAA++YY K + LS+
Sbjct 134 ERSFSRKINEILLALQIERQLTKDEILELYVNKIYLGNRAYGIEAAAQVYYGKPIKDLSL 193
Query 200 AEMAMISGLPKAPSKYNPVVNPERALERRNWILGRMLQLGYINQTQYQQAVAEPINLDMP 259
AEMAMI+GLPKAPS+YNP+VNP R+ ERRNWIL RML+LG+I+Q +YQ AV EPIN
Sbjct 194 AEMAMIAGLPKAPSRYNPLVNPTRSTERRNWILERMLKLGFIDQQRYQAAVEEPINASYH 253
Query 260 DRGVSNRYPYIGEMVRAELVEKFGEQAVDSGYKVYTTINSQRQAYAEQSVQDGLEAYDRR 319
+ PYI EM RAE+V ++G +A GYKV TT+ S Q A QSV+DGL YD+R
Sbjct 254 VQTPELNAPYIAEMARAEMVGRYGSEAYTEGYKVITTVRSDLQNAASQSVRDGLIDYDQR 313
Query 320 HGWRGAE---------AHDKPLRNFIPYANTFPAEVIKVGNNSFDALMQDGKTVTVPWSG 370
HG+RG E A K L PA V +V + + +DGK V W
Sbjct 314 HGYRGPETRLPGQTRDAWLKHLGQQRSIGGLEPAIVTQVEKSGIMVMTRDGKEEAVTWDS 373
Query 371 MSWARRYRNANSVGESPSRASQIVKVKDIVRLRPNGDKSAWSLVQIPKVQGQLIALNPND 430
M WAR + + NS+G P + + + + D +R++ D VQIP Q LI+L+P D
Sbjct 374 MKWARPFLSNNSMGPMPRQPADVAQAGDQIRVQRQED-GTLRFVQIPAAQSALISLDPKD 432
Query 431 GSIEALVGGYNFYQSKFNRALQGWRQPGSTIKPFIYALALERGMTPYTMVNDSPISI--- 487
G+I +LVGG++F QS +NRA+Q RQPGS+ KPFIY+ AL+ G T ++VND+PI
Sbjct 433 GAIRSLVGGFSFEQSNYNRAIQAKRQPGSSFKPFIYSAALDNGFTAASLVNDAPIVFVDE 492
Query 488 ---GRWSPKNSDGRYLGMIPLRRALYLSRNTVSVRLLQSVGVERARQLLMDFGLQENQIP 544
W PKN +LG IPLR ALY SRN VS+R+LQ +G+ERA + FG Q +++P
Sbjct 493 YLDKVWRPKNDTNTFLGPIPLREALYKSRNMVSIRVLQGLGIERAISYITKFGFQRDELP 552
Query 545 RNFTIALGTPQVLPIQMATGYATFANGGYRIQPHFIRRIEDAYGNVIFETKPEYACIPCI 604
RNF++ALGT V P+++A ++ FANGGY++ P+ I RIE G V+++ P +P +
Sbjct 553 RNFSLALGTATVTPMEIAGAWSVFANGGYKVNPYVIERIESRDGQVLYQANPPR--VP-V 609
Query 605 NETNNTETEIKPQTPDDEVIE-VNNQSLDEAKTLVSPAKTNPDNNNYRQAQRILKSSSAY 663
E + E D E E + EA+ + + A+T + A+RI+ + +AY
Sbjct 610 EEQVAADAEDAGNPGDPEHPESAEGEGSIEAQQVAAKAQTTFEPT---PAERIIDARTAY 666
Query 664 DMANILRDVILHGTGRAALKIGRDDLGGKTGTTNDAKDAWFAGFNGKLVAVAWVGFDQPT 723
M ++L+DVI GTGR AL + R DL GKTGTTND+KD WF+G+N V WVGFDQP
Sbjct 667 IMTSMLQDVIKRGTGRRALALKRTDLAGKTGTTNDSKDGWFSGYNSDYVTSVWVGFDQPE 726
Query 724 TLGRREYGGVAALPIWTNFMDQSLKGTP 751
TLGRREYGG ALPIW +M +LK P
Sbjct 727 TLGRREYGGTVALPIWIRYMGFALKDKP 754
>P02918 Penicillin-insensitive transglycosylase / Penicillin-sensitive
transpeptidase [Escherichia coli (strain K12)]
Length=850
Score = 565 bits (1457), Expect = 0.0
Identities = 315/791 (40%), Positives = 458/791 (58%), Gaps = 59/791 (7%)
Query 13 FFLLILMVLVSVPMG-FYGMYLYIAPSLPEMSSLKKAPLLKPLQVYTSDNQLIAEYGGKL 71
+FL++ + + + G YG+Y YI P LP++++LK L P+Q+Y++D +LIA+YG K
Sbjct 6 YFLILAVCCILLGAGSIYGLYRYIEPQLPDVATLKDVRLQIPMQIYSADGELIAQYGEKR 65
Query 72 SVPVEYNQIPPTFIHAFLAAEDSSFFEHSGISFKGLGRALSETVTGSNVQTGGSTITMQV 131
+PV +QIPP + AF+A EDS F+EH G+ G+ RA S + + G STIT Q+
Sbjct 66 RIPVTLDQIPPEMVKAFIATEDSRFYEHHGVDPVGIFRAASVALFSGHASQGASTITQQL 125
Query 132 AKNYYLSPERTLKRKLTEIFLARKIEQNLTKQEILSLYVNKIFLGKNAYGIAAAAKIYYN 191
A+N++LSPERTL RK+ E+FLA +IEQ LTK EIL LY+NKI+LG AYG+ AAA++Y+
Sbjct 126 ARNFFLSPERTLMRKIKEVFLAIRIEQLLTKDEILELYLNKIYLGYRAYGVGAAAQVYFG 185
Query 192 KTLDQLSIAEMAMISGLPKAPSKYNPVVNPERALERRNWILGRMLQLGYINQTQYQQAVA 251
KT+DQL++ EMA+I+GLPKAPS +NP+ + +RA+ RRN +L RML GYI Q Q+ Q
Sbjct 186 KTVDQLTLNEMAVIAGLPKAPSTFNPLYSMDRAVARRNVVLSRMLDEGYITQQQFDQTRT 245
Query 252 EPINLDMPDRGVSNRYPYIGEMVRAELVEKFGEQAVDSGYKVYTTINSQRQAYAEQSVQD 311
E IN + ++ PY+ EMVR E+ ++GE A + GY++YTTI + Q A+Q+V++
Sbjct 246 EAINANYHAPEIAFSAPYLSEMVRQEMYNRYGESAYEDGYRIYTTITRKVQQAAQQAVRN 305
Query 312 GLEAYDRRHGWR---------GAEAHDK-----PLRNFIPYANTFPAEVIKVGNNSFDAL 357
+ YD RHG+R G A D L+ Y PA V A+
Sbjct 306 NVLDYDMRHGYRGPANVLWKVGESAWDNNKITDTLKALPTYGPLLPAAVTSANPQQATAM 365
Query 358 MQDGKTVTVPWSGMSWARRYRNANSVGESPSRASQIVKVKDIVRLRPNGDKSAWSLVQIP 417
+ DG TV + G+ WAR YR+ G +P + + +++ + +R GD AW L Q+P
Sbjct 366 LADGSTVALSMEGVRWARPYRSDTQQGPTPRKVTDVLQTGQQIWVRQVGD--AWWLAQVP 423
Query 418 KVQGQLIALNPNDGSIEALVGGYNFYQSKFNRALQGWRQPGSTIKPFIYALALERGMTPY 477
+V L+++NP +G++ ALVGG++F QSKFNRA Q RQ GS IKPF+Y A+++G+T
Sbjct 424 EVNSALVSINPQNGAVMALVGGFDFNQSKFNRATQALRQVGSNIKPFLYTAAMDKGLTLA 483
Query 478 TMVNDSPISI------GRWSPKNSDGRYLGMIPLRRALYLSRNTVSVRLLQSVGVERARQ 531
+M+ND PIS W PKNS +Y G I LR+ L S+N V VR ++++GV+ A +
Sbjct 484 SMLNDVPISRWDASAGSDWQPKNSPPQYAGPIRLRQGLGQSKNVVMVRAMRAMGVDYAAE 543
Query 532 LLMDFGLQENQIPRNFTIALGTPQVLPIQMATGYATFANGGYRIQPHFIRRIEDAYGNVI 591
L FG I ++ALG+ P+Q+A GYA ANGG+ + P FI +IE+ G VI
Sbjct 544 YLQRFGFPAQNIVHTESLALGSASFTPMQVARGYAVMANGGFLVDPWFISKIENDQGGVI 603
Query 592 FETKPEYACIPC-----------INETNNTETEIKPQTPDDEVIEVNNQSLDEAKTLVSP 640
FE KP+ AC C N N + E + + + + V L++A +
Sbjct 604 FEAKPKVACPECDIPVIYGDTQKSNVLENNDVEDVAISREQQNVSVPMPQLEQANQAL-V 662
Query 641 AKTNPDNNNYRQAQRILKSSSAYDMANILRDVIL-----HGTG-RAALKIGRDDLGGKTG 694
AKT A ++ + A+ + + L I GTG RA + R D+GGKTG
Sbjct 663 AKTGAQ----EYAPHVINTPLAFLIKSALNTNIFGEPGWQGTGWRAGRDLQRRDIGGKTG 718
Query 695 TTNDAKDAWFAGFNGKLVAVAWVGFDQ--------------PTTLGRREYGGVAALPIWT 740
TTN +KDAWF+G+ +V W+GFD + E G +A P W
Sbjct 719 TTNSSKDAWFSGYGPGVVTSVWIGFDDHRRNLGHTTASGAIKDQISGYEGGAKSAQPAWD 778
Query 741 NFMDQSLKGTP 751
+M L+G P
Sbjct 779 AYMKAVLEGVP 789
>Q87AW7 Penicillin-insensitive transglycosylase / Penicillin-sensitive
transpeptidase [Xylella fastidiosa (strain Temecula1
/ ATCC 700964)]
Length=809
Score = 561 bits (1445), Expect = 0.0
Identities = 314/762 (41%), Positives = 452/762 (59%), Gaps = 37/762 (5%)
Query 15 LLILMVLVSVPMGFYGMYLYIAPSLPEMSSLKKAPLLKPLQVYTSDNQLIAEYGGKLSVP 74
+LI++ LV + + MY I+ LP++ +LK+ L +P+ VY+ D LIA +G P
Sbjct 14 ILIILTLVGI-LAAGSMYYAISSKLPDIRNLKQVELQEPMYVYSHDGLLIAIFGEIRRYP 72
Query 75 VEYNQIPPTFIHAFLAAEDSSFFEHSGISFKGLGRALSETVTGSNVQT-GGSTITMQVAK 133
V+ ++P AFLA ED+ F+EHSGI +KG+ RA+ T + + GGSTIT QVA+
Sbjct 73 VQIKEVPEQLKQAFLATEDARFYEHSGIDYKGIARAIWLLATTNEKRVPGGSTITQQVAR 132
Query 134 NYYLSPERTLKRKLTEIFLARKIEQNLTKQEILSLYVNKIFLGKNAYGIAAAAKIYYNKT 193
++L+ E + KRKL EI LARKIE L K EIL LY+NK F G AYGIAAAA+ YY K
Sbjct 133 QFFLNSEYSYKRKLAEILLARKIESQLKKDEILELYLNKSFFGNRAYGIAAAAEFYYGKK 192
Query 194 LDQLSIAEMAMISGLPKAPSKYNPVVNPERALERRN-WILGRMLQLGYINQTQYQQAVAE 252
L++L++ EMA ++G+PK PS NP+ NP RA ERR+ ++L RM+ L +I Q Q A A
Sbjct 193 LNELNLDEMASLAGIPKFPSSGNPITNPARARERRDLYVLQRMVDLNFITQDQANAAKAI 252
Query 253 PINLDMPDRGVSNRYPYIGEMVRAELVEKFGEQAVDSGYKVYTTINSQRQAYAEQSVQDG 312
P++ + V PY EMVR E++ K+G A++ GY V TTI+ Q AE SV++G
Sbjct 253 PMHAKPHEPPVQVYAPYAAEMVRQEMIAKYGGAALNKGYHVTTTIDGTLQMAAETSVRNG 312
Query 313 LEAYDRRHGWRGAEAHDKPLRNFIPYANTFPAEVIKVGNNSFDALMQDGKTVTVPWSGMS 372
L Y+ RH WRGAE H + N A+T G +S + T P
Sbjct 313 LALYEHRHRWRGAEQHIEVDAN----ADTATLAAHLSGISSQGGMFPVIVARTTPEGSAI 368
Query 373 WARRYRNANSVGESPSR-----ASQIVKVKDIVRLRPNGDKSAWSLVQIPKVQGQLIALN 427
R R+ ++ + SR ++++K D+VR+RP + W+L Q+P Q L++L+
Sbjct 369 VVRSDRSELTLPPAASRWTGTPLNKLLKRGDVVRVRPGEKRGEWTLEQLPSAQSTLVSLD 428
Query 428 PNDGSIEALVGGYNFYQSKFNRALQGWRQPGSTIKPFIYALALERGMTPYTMVNDSPISI 487
N+G++ ALVGG++F +KFNRA Q RQPGS+ KPF+Y+ ALE+G P ++V D+P+
Sbjct 429 ANNGALRALVGGFSFTANKFNRATQARRQPGSSFKPFVYSAALEKGFNPASIVPDAPVIF 488
Query 488 -----GRWSPKNSDGRYLGMIPLRRALYLSRNTVSVRLLQSVGVERARQLLMDFGLQENQ 542
WSP+N DG++ G + +R AL SRN VSVRLL ++G++ AR + FG +EN+
Sbjct 489 RDRRGHTWSPQNDDGKFQGPMRIRDALVQSRNLVSVRLLDAIGIDFARNYITQFGFEENE 548
Query 543 IPRNFTIALGTPQVLPIQMATGYATFANGGYRIQPHFIRRIEDAYGNVIFETKPEYACIP 602
IP N +++LGT + P+ +A GYA FANGG+RI P I I D +IF+ P+ AC
Sbjct 549 IPPNLSMSLGTASLTPLSIARGYAVFANGGFRIDPWLIDEIHDREHKLIFKNNPKVACSS 608
Query 603 CIN-ETNNTETE----------IKPQTPDDEVIEVNNQSLDEAKTLVSPAKTNPDNNNYR 651
C + TN T++ +T + ++ NN + +T+ SP P
Sbjct 609 CTSANTNVTQSTSHLVDGFNFGAPTKTEPSKPVKNNN---EPTQTIPSPDPNTP------ 659
Query 652 QAQRILKSSSAYDMANILRDVILHGTGRAALKIGRDDLGGKTGTTNDAKDAWFAGFNGKL 711
A R + + + +++RDV+L GT AA + R D+ GKTG+TN+ +DAWF+GF G
Sbjct 660 MAPRAIDERVVFQLVSMMRDVVLRGTATAARSLNRQDIAGKTGSTNEHRDAWFSGFGGPY 719
Query 712 VAVAWVGFDQPTTLGRREYGGVAALPIWTNFMDQSLKGTPSA 753
V WVG D +LG REYGG AALPIW +M +LK P A
Sbjct 720 VTTVWVGRDDFQSLGYREYGGKAALPIWIEYMRTALKDKPIA 761
>Q9PGD4 Penicillin-insensitive transglycosylase / Penicillin-sensitive
transpeptidase [Xylella fastidiosa (strain 9a5c)]
Length=809
Score = 559 bits (1440), Expect = 0.0
Identities = 313/770 (41%), Positives = 451/770 (59%), Gaps = 53/770 (7%)
Query 15 LLILMVLVSVPMGFYGMYLYIAPSLPEMSSLKKAPLLKPLQVYTSDNQLIAEYGGKLSVP 74
+LI++ LV + + GMY I+ LP++ +LK+ L +P+ VY+ D L+A +G P
Sbjct 14 ILIILTLVGI-LAAGGMYYAISSKLPDIRNLKQVELQEPMYVYSHDGLLMAIFGEIRRYP 72
Query 75 VEYNQIPPTFIHAFLAAEDSSFFEHSGISFKGLGRALSETVTGSNVQT-GGSTITMQVAK 133
V+ ++P AFLA ED+ F+EHSGI +KG+ RA+ T + + GGSTIT QVA+
Sbjct 73 VQIKEVPEQLKQAFLATEDARFYEHSGIDYKGIARAIWLLATTNEKRVPGGSTITQQVAR 132
Query 134 NYYLSPERTLKRKLTEIFLARKIEQNLTKQEILSLYVNKIFLGKNAYGIAAAAKIYYNKT 193
++L+ E + KRKL EI LARKIE L K EIL LY+NK F G AYGIAAAA+ YY K
Sbjct 133 QFFLNSEYSYKRKLAEILLARKIESQLKKDEILELYLNKSFFGNRAYGIAAAAEFYYGKK 192
Query 194 LDQLSIAEMAMISGLPKAPSKYNPVVNPERALERRN-WILGRMLQLGYINQTQYQQAVAE 252
L++L++ EMA ++G+PK PS NP+ NP RA ERR+ ++L RM+ L +I Q Q A A
Sbjct 193 LNELNLDEMASLAGIPKFPSSGNPITNPARARERRDLYVLQRMVDLNFITQDQANAAKAI 252
Query 253 PINLDMPDRGVSNRYPYIGEMVRAELVEKFGEQAVDSGYKVYTTINSQRQAYAEQSVQDG 312
P++ + V PY EMVR E++ K+G A++ GY V TTI+ Q AE SV++G
Sbjct 253 PMHAKPHEPPVQVYAPYAAEMVRQEMIAKYGGAALNKGYHVTTTIDGTLQMAAETSVRNG 312
Query 313 LEAYDRRHGWRGAEAHDK------------PLRNFIPYANTFPAEVIK-VGNNSFDALMQ 359
L Y+ RH WRGAE H + L FP V + S +
Sbjct 313 LALYEHRHRWRGAEQHIEVDANADTATLAAHLSGISSQGGMFPVIVARTTPEGSAVVVRS 372
Query 360 DGKTVTVPWSGMSWARRYRNANSVGESPSRASQIVKVKDIVRLRPNGDKSAWSLVQIPKV 419
D +T+P + W + + ++++K D+VR+RP W+L Q+P
Sbjct 373 DRSELTLPPAAARW------------TGTPLNKLLKRGDVVRVRPGEKWGEWTLEQLPSA 420
Query 420 QGQLIALNPNDGSIEALVGGYNFYQSKFNRALQGWRQPGSTIKPFIYALALERGMTPYTM 479
Q L++L+ N+G++ ALVGG++F +KFNRA Q RQPGS+ KPF+Y+ ALE+G P ++
Sbjct 421 QSTLVSLDANNGALRALVGGFSFTANKFNRATQARRQPGSSFKPFVYSAALEKGFNPASI 480
Query 480 VNDSPISI-----GRWSPKNSDGRYLGMIPLRRALYLSRNTVSVRLLQSVGVERARQLLM 534
V D+P+ WSP+N DG++ G + +R AL SRN VSVRLL ++GV+ AR +
Sbjct 481 VPDAPVIFRDRRGHTWSPQNDDGKFQGPMRIRDALVQSRNLVSVRLLDAIGVDFARNYIT 540
Query 535 DFGLQENQIPRNFTIALGTPQVLPIQMATGYATFANGGYRIQPHFIRRIEDAYGNVIFET 594
FG +EN+IP N +++LGT + P+ +A GYA FANGG+RI P I I D +IF+
Sbjct 541 QFGFEENEIPPNLSMSLGTASLTPLSIARGYAVFANGGFRIDPWLIDEIHDREHKLIFKN 600
Query 595 KPEYACIPCIN-ETNNTETEIK----------PQTPDDEVIEVNNQSLDEAKTLVSPAKT 643
P+ AC C + TN T++ + +T + ++ NN + +T+ SP
Sbjct 601 TPKVACRSCTSANTNVTQSTSQLVDGFNFGAPTKTEPSKPVKNNN---EPPQTIPSPDPN 657
Query 644 NPDNNNYRQAQRILKSSSAYDMANILRDVILHGTGRAALKIGRDDLGGKTGTTNDAKDAW 703
P A R + + + +++RDV+L GT AA + R D+ GKTG+TN+ +DAW
Sbjct 658 TP------MAPRAIDERVVFQLVSMMRDVVLRGTATAARSLNRQDIAGKTGSTNEHRDAW 711
Query 704 FAGFNGKLVAVAWVGFDQPTTLGRREYGGVAALPIWTNFMDQSLKGTPSA 753
F+GF G V WVG D +LG REYGG AALPIW +M +LK P A
Sbjct 712 FSGFGGPYVTTVWVGRDDFQSLGYREYGGKAALPIWIEYMRTALKDKPIA 761
>O87626 Penicillin-insensitive transglycosylase / Penicillin-sensitive
transpeptidase [Neisseria flavescens]
Length=798
Score = 528 bits (1359), Expect = 5e-179
Identities = 307/818 (38%), Positives = 442/818 (54%), Gaps = 92/818 (11%)
Query 37 PSLPEMSSLKKAPLLKPLQVYTSDNQLIAEYGGKLSVPVEYNQIPPTFIHAFLAAEDSSF 96
P LP + SL+ PL +Y+SD Q+I YG + + + P A +AAED F
Sbjct 33 PKLPSLDSLQHYKPKLPLTIYSSDGQVIGVYGEQRREFTKIDDFPKILKDAVIAAEDKRF 92
Query 97 FEHSGISFKGLGRALSETVTGSNVQTGGSTITMQVAKNYYLSPERTLKRKLTEIFLARKI 156
++H G+ G+ RA+ V VQ+G STIT QVAKN+YLS ER+ RK E LA KI
Sbjct 93 YDHWGVDVWGVARAVIGNVMAGGVQSGASTITQQVAKNFYLSSERSFTRKFNEALLAYKI 152
Query 157 EQNLTKQEILSLYVNKIFLGKNAYGIAAAAKIYYNKTLDQLSIAEMAMISGLPKAPSKYN 216
EQ+L+K +IL LY N+I+LG+ AYG A+AA+ Y+NK ++ L++AE AM++GLPKAPS YN
Sbjct 153 EQSLSKDKILELYFNQIYLGQRAYGFASAAQTYFNKNVNDLTLAEAAMLAGLPKAPSAYN 212
Query 217 PVVNPERALERRNWILGRMLQLGYINQTQYQQAVAEPINLDMPDRGVSNRYPYIGEMVRA 276
P+VNPERA R+ +IL ML+ G I Q QA+ E ++ + + + Y+ EM R
Sbjct 213 PIVNPERAKLRQAYILNNMLEEGMITLQQRDQALKEELHYERFVQNIDQSALYVAEMARQ 272
Query 277 ELVEKFGEQAVDSGYKVYTTINSQRQAYAEQSVQDGLEAYDRRHGWRGAEAH------DK 330
EL EK+GE A G+KVYTT+++ Q A ++++ L +DR +RGAE + D
Sbjct 273 ELFEKYGEDAYTQGFKVYTTVDTAHQRVATEALRKVLRNFDRGSSYRGAENYIDLSKSDN 332
Query 331 PLRNFIPYANT-------FPAEVIKVGNNSFDALMQDGKTVTVPWSGMSWARRYRNANSV 383
Y +T PA V++ + G+ VT+ + +A R N +
Sbjct 333 VEETVSQYLSTLYTVDKMIPAVVLEASRKGVQIQLPSGRKVTLNNHALGFAARAVNNEKM 392
Query 384 GESPSRASQIVKVKDIVRLRPNGDKSAWSLVQIPKVQGQLIALNPNDGSIEALVGGYNFY 443
G+ R +++VK G +++VQ P +QG L++L+ G++ ALVGGY+++
Sbjct 393 GDDRIRRGSVIRVK--------GSGDTFTVVQEPLLQGALVSLDAKTGAVRALVGGYDYH 444
Query 444 QSKFNRALQGWRQPGSTIKPFIYALALERGMTPYTMVNDSPISI-------GRWSPKNSD 496
FNRA Q RQPGST KPFIY+ AL +GMT TM+ND+PIS+ W+PKNSD
Sbjct 445 SKTFNRATQAMRQPGSTFKPFIYSAALAKGMTASTMINDAPISLPGKGANGKAWNPKNSD 504
Query 497 GRYLGMIPLRRALYLSRNTVSVRLLQSVGVERARQLLMDFGLQENQIPRNFTIALGTPQV 556
GRY G I LR+AL S+N VS+R+L S+G+ A+Q + FG + ++IP + ++ALG +
Sbjct 505 GRYAGYITLRQALTASKNMVSIRILMSIGIGYAQQYIQRFGFKPSEIPASLSMALGAGET 564
Query 557 LPIQMATGYATFANGGYRIQPHFIRRIEDAYGNVIFETKPEYACIPCINETNNTETEIKP 616
P+++A GY+ FANGGY++ H I +I D+ G + + +P A E P
Sbjct 565 TPLRIAEGYSVFANGGYKVSAHVIDKIYDSQGRLRAQMQPLVA------------GENAP 612
Query 617 QTPDDEVIEVNNQSLDEAKTLVSPAKTNPDNNNYRQAQRILKSSSAYDMANILRDVILHG 676
Q D +AY M I++DV+ G
Sbjct 613 QAIDPR--------------------------------------NAYIMYKIMQDVVRVG 634
Query 677 TGRAALKIGRDDLGGKTGTTNDAKDAWFAGFNGKLVAVAWVGFDQPTTLGRREYGGVAAL 736
T R A +GR D+ GKTGTTND KDAWF GFN +V ++GFD+P ++GR YGG A+
Sbjct 635 TARGAATLGRSDIAGKTGTTNDNKDAWFVGFNPNVVTAVYIGFDKPRSMGRAGYGGTIAV 694
Query 737 PIWTNFMDQSLKGTPSAWVRFDKNAKAPLSREKPTIEIQNREDDQASPPLA--RPLYVPA 794
P+W ++ +LKGT K KAP E+ RE S LA P
Sbjct 695 PVWVEYIGFALKGTSV------KPMKAPEGVVTNGGEVYMRERMTTSSDLALDNSGIRPR 748
Query 795 PVTPARTPDSDFADLPGEEILVPSQGQPPSMQQQPSSP 832
P PAR +P E P+ ++ +P
Sbjct 749 PTQPARRA------VPNENRRRAESNTAPAREESDETP 780
>Q9KNU5 Penicillin-insensitive transglycosylase / Penicillin-sensitive
transpeptidase [Vibrio cholerae serotype O1 (strain
ATCC 39315 / El Tor Inaba N16961)]
Length=825
Score = 528 bits (1361), Expect = 6e-179
Identities = 296/778 (38%), Positives = 440/778 (57%), Gaps = 64/778 (8%)
Query 16 LILMVLVSVPMG---FYGMYLYIAPSLPEMSSLKKAPLLKPLQVYTSDNQLIAEYGGKLS 72
L++ L+ + +G +G Y Y+ LP++++L+ L P+QV++ D +LIA++G K
Sbjct 7 LLVFSLICIILGVTTIFGFYFYVKSDLPDVATLRDVQLQTPMQVFSQDGKLIAQFGEKRR 66
Query 73 VPVEYNQIPPTFIHAFLAAEDSSFFEHSGISFKGLGRALSETVTGSNVQTGGSTITMQVA 132
+P++ ++P I A +A EDS ++EH G G+ RA + + G STIT Q+A
Sbjct 67 IPLKLEEMPKELIEAVIATEDSRYYEHYGFDPIGITRAAFAVLASGSASQGASTITQQLA 126
Query 133 KNYYLSPERTLKRKLTEIFLARKIEQNLTKQEILSLYVNKIFLGKNAYGIAAAAKIYYNK 192
+N++LS E+ + RK+ EIF+A IEQ L+KQEIL LY+NKI+LG +YG+ AAA+ Y+ K
Sbjct 127 RNFFLSNEKKVMRKVKEIFIAIHIEQLLSKQEILELYLNKIYLGYRSYGVGAAAQAYFGK 186
Query 193 TLDQLSIAEMAMISGLPKAPSKYNPVVNPERALERRNWILGRMLQLGYINQTQYQQAVAE 252
+ L++ E+A+I+GLPKAPS NP+ + ERA RRN +L RML YI + +Y A AE
Sbjct 187 EVKDLTLGEIALIAGLPKAPSTMNPIYSVERATNRRNVVLQRMLDEKYITKAEYDAARAE 246
Query 253 PINLDMPDRGVSNRYPYIGEMVRAELVEKFGEQAV-DSGYKVYTTINSQRQAYAEQSVQD 311
P+ + PY+ E+ RA +VE++GE+A SG VYTT++S+ Q A Q+ +
Sbjct 247 PVLPKYHGAEIELNAPYVAEIARAWMVERYGEEAAYTSGMNVYTTVDSKLQRAANQAAIN 306
Query 312 GLEAYDRRHGWRGAEAH--------------DKPLRNFIPYANTFPAEVIKVGNNSFDAL 357
L AYD RHG+RGAE + L N Y + FPA V+ V S
Sbjct 307 NLLAYDERHGYRGAEKELWQVNQPAWSSTQLSEYLSNEPTYGDMFPAAVLSVEEKSAQVW 366
Query 358 MQDGKTVTVPWSGMSWARRYRNANSVGESPSRASQIVKVKDIVRLRP---NGDKSAWSLV 414
++ T+ W M+WARR+ N + G P A++ + + +RP +G +AW L
Sbjct 367 VKSYGVQTIAWEDMNWARRFINDDRQGPLPKSANEFLAAGQQIWVRPRTQDGAITAWKLT 426
Query 415 QIPKVQGQLIALNPNDGSIEALVGGYNFYQSKFNRALQGWRQPGSTIKPFIYALALERGM 474
Q+P +A+NP +G++ ALVGG+NF +KFNRA Q RQ GS+IKPFIY+ AL +G+
Sbjct 427 QVPNANTAFVAMNPENGAVTALVGGFNFVHNKFNRATQSVRQVGSSIKPFIYSAALNKGL 486
Query 475 TPYTMVNDSPISIG------RWSPKNSDGRYLGMIPLRRALYLSRNTVSVRLLQSVGVER 528
T T++ND+PI+ W PKNS Y G LR L S+N ++VR+L+ VG++
Sbjct 487 TLATLINDAPINQWDESQGTAWRPKNSPPTYTGPTRLRIGLAQSKNVMAVRVLREVGLDE 546
Query 529 ARQLLMDFGLQENQIPRNFTIALGTPQVLPIQMATGYATFANGGYRIQPHFIRRIEDAYG 588
R+ L FG + +Q+PR+ TIALG + P+QMA G++ FAN GY ++P +I R+E+ +G
Sbjct 547 TREYLTRFGFKLDQLPRSETIALGAGSLTPVQMAQGFSVFANNGYFVEPFYISRVENPFG 606
Query 589 NVIFETKPEYACI-PCINETNNTETEIKPQTPDDEVIEVNNQSLDEAKTLVSPAKTNPDN 647
N+ F +P+ C C +E + + +VI N L
Sbjct 607 NIEFSAEPKVVCHRECSSELDEFAEQDAASPYAPKVISEQNAFLT--------------- 651
Query 648 NNYRQAQRILKSSSAYDMANILRDVILHGTGRAALKIGRDDLGGKTGTTNDAKDAWFAGF 707
R + S+ + D +GTG A + R D+GGKTGTTND+KDAW+ G+
Sbjct 652 -------REMLYSNIWGGGEWSSDTGWNGTGWRAQALKRRDIGGKTGTTNDSKDAWYNGY 704
Query 708 NGKLVAVAWVGFDQPT-TLGR-------------REYGGVAALPIWTNFMDQSLKGTP 751
+V VAWVGFD + LG+ E GG ALP W FM +L+ P
Sbjct 705 APGIVGVAWVGFDDHSRNLGKTAPNRNIEDDVSGAESGGKTALPAWVEFMSLALQDVP 762
>P0A0Z6 Penicillin-insensitive transglycosylase / Penicillin-sensitive
transpeptidase [Neisseria meningitidis serogroup B
(strain MC58)]
Length=798
Score = 522 bits (1344), Expect = 9e-177
Identities = 290/734 (40%), Positives = 418/734 (57%), Gaps = 79/734 (11%)
Query 37 PSLPEMSSLKKAPLLKPLQVYTSDNQLIAEYGGKLSVPVEYNQIPPTFIHAFLAAEDSSF 96
P LP + SL+ PL +Y++D ++I YG + + P +A +AAED F
Sbjct 33 PKLPSLDSLQHYQPKMPLTIYSADGEVIGMYGEQRREFTKIGDFPEVLRNAVIAAEDKRF 92
Query 97 FEHSGISFKGLGRALSETVTGSNVQTGGSTITMQVAKNYYLSPERTLKRKLTEIFLARKI 156
+ H G+ G+ RA V +VQ+G STIT QVAKN+YLS E+T RK E+ LA KI
Sbjct 93 YRHWGVDVWGVARAAVGNVVSGSVQSGASTITQQVAKNFYLSSEKTFTRKFNEVLLAYKI 152
Query 157 EQNLTKQEILSLYVNKIFLGKNAYGIAAAAKIYYNKTLDQLSIAEMAMISGLPKAPSKYN 216
EQ+L+K +IL LY N+I+LG+ AYG A+AA+IY+NK + L++AE AM++GLPKAPS YN
Sbjct 153 EQSLSKDKILELYFNQIYLGQRAYGFASAAQIYFNKNVRDLTLAEAAMLAGLPKAPSAYN 212
Query 217 PVVNPERALERRNWILGRMLQLGYINQTQYQQAVAEPINLDMPDRGVSNRYPYIGEMVRA 276
P+VNPERA R+ +IL ML+ I Q QA+ E ++ + R + Y+ EMVR
Sbjct 213 PIVNPERAKLRQKYILNNMLEEKMITVQQRDQALNEELHYERFVRKIDQSALYVAEMVRQ 272
Query 277 ELVEKFGEQAVDSGYKVYTTINSQRQAYAEQSVQDGLEAYDRRHGWRGAEAH-------- 328
EL EK+GE A G+KVYTT+ + Q A ++++ L +DR +RGAE +
Sbjct 273 ELYEKYGEDAYTQGFKVYTTVRADHQKVATEALRKALRNFDRGSSYRGAENYIDLSKSED 332
Query 329 -----DKPLRNFIPYANTFPAEVIKVGNNSFDAL-MQDGKTVTVPWSGMSWARRYRNANS 382
+ L PA V+ V + + G+ VT+ + +A R N
Sbjct 333 VEETVSQYLSGLYTVDKMVPAVVLDVTKKKNVVIQLPGGRRVTLDRRALGFAARAVNNEK 392
Query 383 VGESPSRASQIVKVKDIVRLRPNGDKSAWSLVQIPKVQGQLIALNPNDGSIEALVGGYNF 442
+GE R +++VK+ NG + W++VQ P +QG L++L+ G++ ALVGGY+F
Sbjct 393 MGEDRIRRGAVIRVKN------NGGR--WAVVQEPLLQGALVSLDAKTGAVRALVGGYDF 444
Query 443 YQSKFNRALQGWRQPGSTIKPFIYALALERGMTPYTMVNDSPISI-------GRWSPKNS 495
+ FNRA+Q RQPGST KPF+Y+ AL +GMT T+VND+PIS+ W+PKNS
Sbjct 445 HSKTFNRAVQAMRQPGSTFKPFVYSAALSKGMTASTVVNDAPISLPGKGPNGSVWTPKNS 504
Query 496 DGRYLGMIPLRRALYLSRNTVSVRLLQSVGVERARQLLMDFGLQENQIPRNFTIALGTPQ 555
DGRY G I LR+AL S+N VS+R+L S+GV A+Q + FG + +++P + ++ALGT +
Sbjct 505 DGRYSGYITLRQALTASKNMVSIRILMSIGVGYAQQYIRRFGFRSSELPASLSMALGTGE 564
Query 556 VLPIQMATGYATFANGGYRIQPHFIRRIEDAYGNVIFETKPEYACIPCINETNNTETEIK 615
P+++A Y+ FANGGYR+ H I +I D G + + +P A N I
Sbjct 565 TTPLKVAEAYSVFANGGYRVSSHVIDKIYDRDGRLRAQMQPLVA-------GQNAPQAID 617
Query 616 PQTPDDEVIEVNNQSLDEAKTLVSPAKTNPDNNNYRQAQRILKSSSAYDMANILRDVILH 675
P+ +AY M I++DV+
Sbjct 618 PR-------------------------------------------NAYIMYKIMQDVVRV 634
Query 676 GTGRAALKIGRDDLGGKTGTTNDAKDAWFAGFNGKLVAVAWVGFDQPTTLGRREYGGVAA 735
GT R A +GR D+ GKTGTTND KDAWF GFN +V ++GFD+P ++GR YGG A
Sbjct 635 GTARGAAALGRTDIAGKTGTTNDNKDAWFVGFNPDVVTAVYIGFDKPKSMGRVGYGGTIA 694
Query 736 LPIWTNFMDQSLKG 749
+P+W ++M +LKG
Sbjct 695 VPVWVDYMRFALKG 708
>P0A0Z5 Penicillin-insensitive transglycosylase / Penicillin-sensitive
transpeptidase [Neisseria meningitidis serogroup A
/ serotype 4A (strain DSM 15465 / Z2491)]
Length=798
Score = 522 bits (1344), Expect = 9e-177
Identities = 290/734 (40%), Positives = 418/734 (57%), Gaps = 79/734 (11%)
Query 37 PSLPEMSSLKKAPLLKPLQVYTSDNQLIAEYGGKLSVPVEYNQIPPTFIHAFLAAEDSSF 96
P LP + SL+ PL +Y++D ++I YG + + P +A +AAED F
Sbjct 33 PKLPSLDSLQHYQPKMPLTIYSADGEVIGMYGEQRREFTKIGDFPEVLRNAVIAAEDKRF 92
Query 97 FEHSGISFKGLGRALSETVTGSNVQTGGSTITMQVAKNYYLSPERTLKRKLTEIFLARKI 156
+ H G+ G+ RA V +VQ+G STIT QVAKN+YLS E+T RK E+ LA KI
Sbjct 93 YRHWGVDVWGVARAAVGNVVSGSVQSGASTITQQVAKNFYLSSEKTFTRKFNEVLLAYKI 152
Query 157 EQNLTKQEILSLYVNKIFLGKNAYGIAAAAKIYYNKTLDQLSIAEMAMISGLPKAPSKYN 216
EQ+L+K +IL LY N+I+LG+ AYG A+AA+IY+NK + L++AE AM++GLPKAPS YN
Sbjct 153 EQSLSKDKILELYFNQIYLGQRAYGFASAAQIYFNKNVRDLTLAEAAMLAGLPKAPSAYN 212
Query 217 PVVNPERALERRNWILGRMLQLGYINQTQYQQAVAEPINLDMPDRGVSNRYPYIGEMVRA 276
P+VNPERA R+ +IL ML+ I Q QA+ E ++ + R + Y+ EMVR
Sbjct 213 PIVNPERAKLRQKYILNNMLEEKMITVQQRDQALNEELHYERFVRKIDQSALYVAEMVRQ 272
Query 277 ELVEKFGEQAVDSGYKVYTTINSQRQAYAEQSVQDGLEAYDRRHGWRGAEAH-------- 328
EL EK+GE A G+KVYTT+ + Q A ++++ L +DR +RGAE +
Sbjct 273 ELYEKYGEDAYTQGFKVYTTVRADHQKVATEALRKALRNFDRGSSYRGAENYIDLSKSED 332
Query 329 -----DKPLRNFIPYANTFPAEVIKVGNNSFDAL-MQDGKTVTVPWSGMSWARRYRNANS 382
+ L PA V+ V + + G+ VT+ + +A R N
Sbjct 333 VEETVSQYLSGLYTVDKMVPAVVLDVTKKKNVVIQLPGGRRVTLDRRALGFAARAVNNEK 392
Query 383 VGESPSRASQIVKVKDIVRLRPNGDKSAWSLVQIPKVQGQLIALNPNDGSIEALVGGYNF 442
+GE R +++VK+ NG + W++VQ P +QG L++L+ G++ ALVGGY+F
Sbjct 393 MGEDRIRRGAVIRVKN------NGGR--WAVVQEPLLQGALVSLDAKTGAVRALVGGYDF 444
Query 443 YQSKFNRALQGWRQPGSTIKPFIYALALERGMTPYTMVNDSPISI-------GRWSPKNS 495
+ FNRA+Q RQPGST KPF+Y+ AL +GMT T+VND+PIS+ W+PKNS
Sbjct 445 HSKTFNRAVQAMRQPGSTFKPFVYSAALSKGMTASTVVNDAPISLPGKGPNGSVWTPKNS 504
Query 496 DGRYLGMIPLRRALYLSRNTVSVRLLQSVGVERARQLLMDFGLQENQIPRNFTIALGTPQ 555
DGRY G I LR+AL S+N VS+R+L S+GV A+Q + FG + +++P + ++ALGT +
Sbjct 505 DGRYSGYITLRQALTASKNMVSIRILMSIGVGYAQQYIRRFGFRSSELPASLSMALGTGE 564
Query 556 VLPIQMATGYATFANGGYRIQPHFIRRIEDAYGNVIFETKPEYACIPCINETNNTETEIK 615
P+++A Y+ FANGGYR+ H I +I D G + + +P A N I
Sbjct 565 TTPLKVAEAYSVFANGGYRVSSHVIDKIYDRDGRLRAQMQPLVA-------GQNAPQAID 617
Query 616 PQTPDDEVIEVNNQSLDEAKTLVSPAKTNPDNNNYRQAQRILKSSSAYDMANILRDVILH 675
P+ +AY M I++DV+
Sbjct 618 PR-------------------------------------------NAYIMYKIMQDVVRV 634
Query 676 GTGRAALKIGRDDLGGKTGTTNDAKDAWFAGFNGKLVAVAWVGFDQPTTLGRREYGGVAA 735
GT R A +GR D+ GKTGTTND KDAWF GFN +V ++GFD+P ++GR YGG A
Sbjct 635 GTARGAAALGRTDIAGKTGTTNDNKDAWFVGFNPDVVTAVYIGFDKPKSMGRVGYGGTIA 694
Query 736 LPIWTNFMDQSLKG 749
+P+W ++M +LKG
Sbjct 695 VPVWVDYMRFALKG 708
>O86088 Penicillin-insensitive transglycosylase / Penicillin-sensitive
transpeptidase [Neisseria cinerea]
Length=798
Score = 519 bits (1337), Expect = 1e-175
Identities = 289/734 (39%), Positives = 417/734 (57%), Gaps = 79/734 (11%)
Query 37 PSLPEMSSLKKAPLLKPLQVYTSDNQLIAEYGGKLSVPVEYNQIPPTFIHAFLAAEDSSF 96
P LP + SL+ PL +Y++D ++I YG + + P +A +AAED F
Sbjct 33 PKLPSLDSLQHYQPKMPLTIYSADGEVIGIYGEQRREFTKIGDFPEVLRNAVIAAEDKRF 92
Query 97 FEHSGISFKGLGRALSETVTGSNVQTGGSTITMQVAKNYYLSPERTLKRKLTEIFLARKI 156
++H G+ G+ RA+ + VQ+G STIT QVAKN+YLS E+T RK E LA KI
Sbjct 93 YQHWGVDVWGVARAVVGNIVAGGVQSGASTITQQVAKNFYLSSEKTFTRKFNEALLAYKI 152
Query 157 EQNLTKQEILSLYVNKIFLGKNAYGIAAAAKIYYNKTLDQLSIAEMAMISGLPKAPSKYN 216
EQ+L+K +IL LY N+I+LG+ AYG A+AA+IY+NK + +L++AE+AM++GLPKAPS YN
Sbjct 153 EQSLSKDKILELYFNQIYLGQRAYGFASAAQIYFNKDVRELTLAEVAMLAGLPKAPSAYN 212
Query 217 PVVNPERALERRNWILGRMLQLGYINQTQYQQAVAEPINLDMPDRGVSNRYPYIGEMVRA 276
P+VNPERA R+ +IL ML+ I Q QA+ E ++ + + + Y+ EMVR
Sbjct 213 PIVNPERAKLRQKYILNNMLEEKMITLQQRDQALNEELHYERFVQKIDQSALYVAEMVRQ 272
Query 277 ELVEKFGEQAVDSGYKVYTTINSQRQAYAEQSVQDGLEAYDRRHGWRGAEAH-------- 328
EL EK+GE A G+KVYTT+ + Q A ++++ L +DR +RGAE++
Sbjct 273 ELYEKYGEDAYTQGFKVYTTVRTDHQKVATEALRKALRNFDRGSSYRGAESYIDLSKGED 332
Query 329 -----DKPLRNFIPYANTFPAEVIKVGNNSFDAL-MQDGKTVTVPWSGMSWARRYRNANS 382
+ L PA V+ V + + GK VT+ + +A R N
Sbjct 333 VEETVSQYLSGLYTVDKMVPAIVLDVTKRKNVVIQLPSGKRVTLDGRSLGFAARAVNNEK 392
Query 383 VGESPSRASQIVKVKDIVRLRPNGDKSAWSLVQIPKVQGQLIALNPNDGSIEALVGGYNF 442
+GES R ++R+R NG + W +VQ P +Q L++L+ G++ ALVGGY+F
Sbjct 393 MGESRIRRG------SVIRVRNNGGR--WVVVQEPLLQATLVSLDAKTGAVRALVGGYDF 444
Query 443 YQSKFNRALQGWRQPGSTIKPFIYALALERGMTPYTMVNDSPISI-------GRWSPKNS 495
+ FNRA Q RQPGST KPFIY+ AL +GMT TMVND+PIS+ W+PKNS
Sbjct 445 HSKTFNRAAQAMRQPGSTFKPFIYSAALSKGMTASTMVNDAPISLPGKGANGSVWTPKNS 504
Query 496 DGRYLGMIPLRRALYLSRNTVSVRLLQSVGVERARQLLMDFGLQENQIPRNFTIALGTPQ 555
DGRY G I LR+AL S+N VS+R+L S+GV A + + FG + +++P + ++ALGT +
Sbjct 505 DGRYSGYITLRQALTASKNMVSIRILMSIGVGYAHEYIQRFGFKPSELPASLSMALGTGE 564
Query 556 VLPIQMATGYATFANGGYRIQPHFIRRIEDAYGNVIFETKPEYACIPCINETNNTETEIK 615
P+++A Y+ FANGGYR+ H I +I + G + + +P A N I
Sbjct 565 TTPLKIAEAYSVFANGGYRVSSHVIDKIYGSDGRLRAQMQPLVA-------GQNAPQAID 617
Query 616 PQTPDDEVIEVNNQSLDEAKTLVSPAKTNPDNNNYRQAQRILKSSSAYDMANILRDVILH 675
P+ +AY M I++DV+
Sbjct 618 PR-------------------------------------------NAYIMYKIMQDVVRV 634
Query 676 GTGRAALKIGRDDLGGKTGTTNDAKDAWFAGFNGKLVAVAWVGFDQPTTLGRREYGGVAA 735
GT R A +GR D+ GKTGTTND KDAWF GFN +V ++GFD+P ++GR YGG A
Sbjct 635 GTARGAAALGRSDIAGKTGTTNDNKDAWFVGFNPDVVTAVYIGFDKPKSMGRAGYGGTIA 694
Query 736 LPIWTNFMDQSLKG 749
+P+W ++M +LKG
Sbjct 695 VPVWVDYMRFALKG 708
>O05131 Penicillin-insensitive transglycosylase / Penicillin-sensitive
transpeptidase [Neisseria gonorrhoeae]
Length=798
Score = 519 bits (1336), Expect = 1e-175
Identities = 301/798 (38%), Positives = 435/798 (55%), Gaps = 85/798 (11%)
Query 37 PSLPEMSSLKKAPLLKPLQVYTSDNQLIAEYGGKLSVPVEYNQIPPTFIHAFLAAEDSSF 96
P LP + SL+ PL +Y++D ++I YG + + P +A +AAED F
Sbjct 33 PKLPSLDSLQHYQPKMPLTIYSADGEVIGMYGEQRREFTKIGDFPEVLRNAVIAAEDKRF 92
Query 97 FEHSGISFKGLGRALSETVTGSNVQTGGSTITMQVAKNYYLSPERTLKRKLTEIFLARKI 156
+ H G+ G+ RA V +VQ+G STIT QVAKN+YLS E+T RK E+ LA KI
Sbjct 93 YRHWGVDVWGVARAAVGNVVSGSVQSGASTITQQVAKNFYLSSEKTFTRKFNEVLLAYKI 152
Query 157 EQNLTKQEILSLYVNKIFLGKNAYGIAAAAKIYYNKTLDQLSIAEMAMISGLPKAPSKYN 216
EQ+L+K +IL LY N+I+LG+ AYG A+AA+IY+NK + L++AE AM++GLPKAPS YN
Sbjct 153 EQSLSKDKILELYFNQIYLGQRAYGFASAAQIYFNKNVRDLTLAEAAMLAGLPKAPSAYN 212
Query 217 PVVNPERALERRNWILGRMLQLGYINQTQYQQAVAEPINLDMPDRGVSNRYPYIGEMVRA 276
P+VNPERA R+ +IL ML+ I Q QA+ E ++ + R + Y+ EMVR
Sbjct 213 PIVNPERAKLRQKYILNNMLEEKMITVQQRDQALNEELHYERFVRKIDQSALYVAEMVRR 272
Query 277 ELVEKFGEQAVDSGYKVYTTINSQRQAYAEQSVQDGLEAYDRRHGWRGAEAH-------- 328
EL EK+GE A G+KVYTT+ + Q A ++++ L +DR +RGAE +
Sbjct 273 ELYEKYGEDAYTQGFKVYTTVRTDHQKAATEALRKALRNFDRGSSYRGAENYIDLSKSED 332
Query 329 -----DKPLRNFIPYANTFPAEVIKVGNNSFDAL-MQDGKTVTVPWSGMSWARRYRNANS 382
+ L PA V+ V + + G+ V + + +A R +
Sbjct 333 VEETVSQYLSGLYTVDKMVPAVVLDVTKKKNVVIQLPGGRRVALDRRALGFAARAVDNEK 392
Query 383 VGESPSRASQIVKVKDIVRLRPNGDKSAWSLVQIPKVQGQLIALNPNDGSIEALVGGYNF 442
+GE R +++VK+ NG + W++VQ P +QG L++L+ G++ ALVGGY+F
Sbjct 393 MGEDRIRRGAVIRVKN------NGGR--WAVVQEPLLQGALVSLDAKTGAVRALVGGYDF 444
Query 443 YQSKFNRALQGWRQPGSTIKPFIYALALERGMTPYTMVNDSPISI-------GRWSPKNS 495
+ FNRA+Q RQPGST KPF+Y+ AL +GMT T+VND+PIS+ W+PKNS
Sbjct 445 HSKTFNRAVQAMRQPGSTFKPFVYSAALSKGMTASTVVNDAPISLPGKGPNGSVWTPKNS 504
Query 496 DGRYLGMIPLRRALYLSRNTVSVRLLQSVGVERARQLLMDFGLQENQIPRNFTIALGTPQ 555
DGRY G I LR+AL S+N VS+R+L S+GV A+Q + FG + +++P + ++ALGT +
Sbjct 505 DGRYSGYITLRQALTASKNMVSIRILMSIGVGYAQQYIRRFGFRPSELPASLSMALGTGE 564
Query 556 VLPIQMATGYATFANGGYRIQPHFIRRIEDAYGNVIFETKPEYACIPCINETNNTETEIK 615
P+++A Y+ FANGGYR+ H I +I D G + + +P A N I
Sbjct 565 TTPLKVAEAYSVFANGGYRVSSHVIDKIYDRDGRLRAQMQPLVA-------GQNAPQAID 617
Query 616 PQTPDDEVIEVNNQSLDEAKTLVSPAKTNPDNNNYRQAQRILKSSSAYDMANILRDVILH 675
P+ +AY M I++DV+
Sbjct 618 PR-------------------------------------------NAYIMYKIMQDVVRV 634
Query 676 GTGRAALKIGRDDLGGKTGTTNDAKDAWFAGFNGKLVAVAWVGFDQPTTLGRREYGGVAA 735
GT R A +GR D+ GKTGTTND KDAWF GFN +V ++GFD+P ++GR YGG A
Sbjct 635 GTARGAAALGRTDIAGKTGTTNDNKDAWFVGFNPDVVTAVYIGFDKPKSMGRAGYGGTIA 694
Query 736 LPIWTNFMDQSLKGTPSAWVRFDKNAKAPLSREKPTIEIQNREDDQASPPLARPLYVPAP 795
+P+W ++M +LKG + K K P E +E P L AP
Sbjct 695 VPVWVDYMRFALKG------KQGKGMKMPEGVVSSNGEYYMKERMVTDPGLMLDNSGIAP 748
Query 796 VTPARTPDSDFADLPGEE 813
R + D A + E+
Sbjct 749 QPSRRAKEDDEAAVENEQ 766
>Q5FAC7 Penicillin-insensitive transglycosylase / Penicillin-sensitive
transpeptidase [Neisseria gonorrhoeae (strain ATCC
700825 / FA 1090)]
Length=798
Score = 519 bits (1336), Expect = 1e-175
Identities = 301/798 (38%), Positives = 435/798 (55%), Gaps = 85/798 (11%)
Query 37 PSLPEMSSLKKAPLLKPLQVYTSDNQLIAEYGGKLSVPVEYNQIPPTFIHAFLAAEDSSF 96
P LP + SL+ PL +Y++D ++I YG + + P +A +AAED F
Sbjct 33 PKLPSLDSLQHYQPKMPLTIYSADGEVIGMYGEQRREFTKIGDFPEVLRNAVIAAEDKRF 92
Query 97 FEHSGISFKGLGRALSETVTGSNVQTGGSTITMQVAKNYYLSPERTLKRKLTEIFLARKI 156
+ H G+ G+ RA V +VQ+G STIT QVAKN+YLS E+T RK E+ LA KI
Sbjct 93 YRHWGVDVWGVARAAVGNVVSGSVQSGASTITQQVAKNFYLSSEKTFTRKFNEVLLAYKI 152
Query 157 EQNLTKQEILSLYVNKIFLGKNAYGIAAAAKIYYNKTLDQLSIAEMAMISGLPKAPSKYN 216
EQ+L+K +IL LY N+I+LG+ AYG A+AA+IY+NK + L++AE AM++GLPKAPS YN
Sbjct 153 EQSLSKDKILELYFNQIYLGQRAYGFASAAQIYFNKNVRDLTLAEAAMLAGLPKAPSAYN 212
Query 217 PVVNPERALERRNWILGRMLQLGYINQTQYQQAVAEPINLDMPDRGVSNRYPYIGEMVRA 276
P+VNPERA R+ +IL ML+ I Q QA+ E ++ + R + Y+ EMVR
Sbjct 213 PIVNPERAKLRQKYILNNMLEEKMITVQQRDQALNEELHYERFVRKIDQSALYVAEMVRR 272
Query 277 ELVEKFGEQAVDSGYKVYTTINSQRQAYAEQSVQDGLEAYDRRHGWRGAEAH-------- 328
EL EK+GE A G+KVYTT+ + Q A ++++ L +DR +RGAE +
Sbjct 273 ELYEKYGEDAYTQGFKVYTTVRTDHQKAATEALRKALRNFDRGSSYRGAENYIDLSKSED 332
Query 329 -----DKPLRNFIPYANTFPAEVIKVGNNSFDAL-MQDGKTVTVPWSGMSWARRYRNANS 382
+ L PA V+ V + + G+ V + + +A R +
Sbjct 333 VEETVSQYLSGLYTVDKMVPAVVLDVTKKKNVVIQLPGGRRVALDRRALGFAARAVDNEK 392
Query 383 VGESPSRASQIVKVKDIVRLRPNGDKSAWSLVQIPKVQGQLIALNPNDGSIEALVGGYNF 442
+GE R +++VK+ NG + W++VQ P +QG L++L+ G++ ALVGGY+F
Sbjct 393 MGEDRIRRGAVIRVKN------NGGR--WAVVQEPLLQGALVSLDAKTGAVRALVGGYDF 444
Query 443 YQSKFNRALQGWRQPGSTIKPFIYALALERGMTPYTMVNDSPISI-------GRWSPKNS 495
+ FNRA+Q RQPGST KPF+Y+ AL +GMT T+VND+PIS+ W+PKNS
Sbjct 445 HSKTFNRAVQAMRQPGSTFKPFVYSAALSKGMTASTVVNDAPISLPGKGPNGSVWTPKNS 504
Query 496 DGRYLGMIPLRRALYLSRNTVSVRLLQSVGVERARQLLMDFGLQENQIPRNFTIALGTPQ 555
DGRY G I LR+AL S+N VS+R+L S+GV A+Q + FG + +++P + ++ALGT +
Sbjct 505 DGRYSGYITLRQALTASKNMVSIRILMSIGVGYAQQYIRRFGFRPSELPASLSMALGTGE 564
Query 556 VLPIQMATGYATFANGGYRIQPHFIRRIEDAYGNVIFETKPEYACIPCINETNNTETEIK 615
P+++A Y+ FANGGYR+ H I +I D G + + +P A N I
Sbjct 565 TTPLKVAEAYSVFANGGYRVSSHVIDKIYDRDGRLRAQMQPLVA-------GQNAPQAID 617
Query 616 PQTPDDEVIEVNNQSLDEAKTLVSPAKTNPDNNNYRQAQRILKSSSAYDMANILRDVILH 675
P+ +AY M I++DV+
Sbjct 618 PR-------------------------------------------NAYIMYKIMQDVVRV 634
Query 676 GTGRAALKIGRDDLGGKTGTTNDAKDAWFAGFNGKLVAVAWVGFDQPTTLGRREYGGVAA 735
GT R A +GR D+ GKTGTTND KDAWF GFN +V ++GFD+P ++GR YGG A
Sbjct 635 GTARGAAALGRTDIAGKTGTTNDNKDAWFVGFNPDVVTAVYIGFDKPKSMGRAGYGGTIA 694
Query 736 LPIWTNFMDQSLKGTPSAWVRFDKNAKAPLSREKPTIEIQNREDDQASPPLARPLYVPAP 795
+P+W ++M +LKG + K K P E +E P L AP
Sbjct 695 VPVWVDYMRFALKG------KQGKGMKMPEGVVSSNGEYYMKERMVTDPGLMLDNSGIAP 748
Query 796 VTPARTPDSDFADLPGEE 813
R + D A + E+
Sbjct 749 QPSRRAKEDDEAAVENEQ 766
>O87579 Penicillin-insensitive transglycosylase / Penicillin-sensitive
transpeptidase [Neisseria lactamica]
Length=798
Score = 518 bits (1334), Expect = 3e-175
Identities = 304/825 (37%), Positives = 444/825 (54%), Gaps = 86/825 (10%)
Query 37 PSLPEMSSLKKAPLLKPLQVYTSDNQLIAEYGGKLSVPVEYNQIPPTFIHAFLAAEDSSF 96
P LP + SL+ PL VY++D ++I YG + + P +A +AAED F
Sbjct 33 PKLPSLDSLQHYQPKMPLTVYSADGKIIGIYGEQRREFTKIGDFPEVLRNAVIAAEDKRF 92
Query 97 FEHSGISFKGLGRALSETVTGSNVQTGGSTITMQVAKNYYLSPERTLKRKLTEIFLARKI 156
++H G+ G+ RA+ + ++Q+G STIT QVAKN+YLS E+T RK E LA KI
Sbjct 93 YQHWGVDVWGVARAVVGNIVSGSMQSGASTITQQVAKNFYLSSEKTFTRKFNEALLAYKI 152
Query 157 EQNLTKQEILSLYVNKIFLGKNAYGIAAAAKIYYNKTLDQLSIAEMAMISGLPKAPSKYN 216
EQ+L+K +IL LY N+I+LG+ AYG A+AA+IY+NK + L++AE AM++GLPKAPS YN
Sbjct 153 EQSLSKDKILELYFNQIYLGQRAYGFASAAQIYFNKDVRDLTLAEAAMLAGLPKAPSAYN 212
Query 217 PVVNPERALERRNWILGRMLQLGYINQTQYQQAVAEPINLDMPDRGVSNRYPYIGEMVRA 276
P+VNPERA R+ +IL ML+ I Q QA+ E ++ + + + Y+ EMVR
Sbjct 213 PIVNPERAKLRQKYILNNMLEEKMITLQQRDQALNEELHYERFVQKIDQSALYVAEMVRQ 272
Query 277 ELVEKFGEQAVDSGYKVYTTINSQRQAYAEQSVQDGLEAYDRRHGWRGAEAH-------- 328
EL EK+GE A G KVYTT+ + Q A ++++ L +DR +RGAE++
Sbjct 273 ELYEKYGEDAYTQGLKVYTTVRTDHQKAATEALRKALRNFDRGSSYRGAESYIDLGRDED 332
Query 329 -----DKPLRNFIPYANTFPAEVIKVGNNSFDAL-MQDGKTVTVPWSGMSWARRYRNANS 382
+ L PA V+ V + + GK VT+ + +A R +
Sbjct 333 AEEAVSQYLSGLYTVDKMVPAVVLDVTKKKNVVIQLPGGKRVTLDRRALGFAARAVDNEK 392
Query 383 VGESPSRASQIVKVKDIVRLRPNGDKSAWSLVQIPKVQGQLIALNPNDGSIEALVGGYNF 442
+GE R ++R+R NG + W++VQ P +QG L++L+ G++ ALVGGY+F
Sbjct 393 MGEDRIRRGA------VIRVRNNGGR--WAVVQEPLLQGALVSLDAKTGAVRALVGGYDF 444
Query 443 YQSKFNRALQGWRQPGSTIKPFIYALALERGMTPYTMVNDSPISI-------GRWSPKNS 495
+ FNRA Q RQPGST KPF+Y+ AL +GMT TM+ND+PIS+ W+PKNS
Sbjct 445 HSKTFNRATQAMRQPGSTFKPFVYSAALSKGMTASTMINDAPISLPGKGPNGSVWTPKNS 504
Query 496 DGRYLGMIPLRRALYLSRNTVSVRLLQSVGVERARQLLMDFGLQENQIPRNFTIALGTPQ 555
DGRY G I LR+AL S+N VS+R+L S+GV A+Q + FG + +++P + ++ALGT +
Sbjct 505 DGRYSGYITLRQALTASKNMVSIRILMSIGVGYAQQYIRRFGFKPSELPVSLSMALGTGE 564
Query 556 VLPIQMATGYATFANGGYRIQPHFIRRIEDAYGNVIFETKPEYACIPCINETNNTETEIK 615
P+++A Y+ FANGGYR+ + I +I D+ G + + +P A N I
Sbjct 565 TTPLRIAEAYSVFANGGYRVSSYVIDKIYDSEGRLRAQMQPLVA-------GQNAPQAID 617
Query 616 PQTPDDEVIEVNNQSLDEAKTLVSPAKTNPDNNNYRQAQRILKSSSAYDMANILRDVILH 675
P+ +AY M I++DV+
Sbjct 618 PR-------------------------------------------NAYIMYKIMQDVVRV 634
Query 676 GTGRAALKIGRDDLGGKTGTTNDAKDAWFAGFNGKLVAVAWVGFDQPTTLGRREYGGVAA 735
GT R A +GR D+ GKTGTTND KDAWF GFN +V ++GFD+P ++GR YGG A
Sbjct 635 GTARGASALGRSDIAGKTGTTNDNKDAWFVGFNPDVVTAVYIGFDKPKSMGRAGYGGTIA 694
Query 736 LPIWTNFMDQSLKGTPSAWVRFDKNAKAPLSREKPTIEIQNREDDQASPPLARPLYVPAP 795
+P+W ++M +LKG P K K P E +E P L AP
Sbjct 695 VPVWVDYMRFALKGRPG------KGMKMPDGVVAGNGEYYMKEHMVTDPGLMLDNGGAAP 748
Query 796 VTPARTPDSDFADLPGEEILVPSQGQPPSMQQQPSSPKKNETPKR 840
R + D G + + MQ+ P P ++ ++
Sbjct 749 QPSRRVKEDDGGAAEGGRQEADDESR-QDMQETPVLPSNTDSKRQ 792
>P31776 Penicillin-insensitive transglycosylase / Penicillin-sensitive
transpeptidase [Haemophilus influenzae (strain ATCC
51907 / DSM 11121 / KW20 / Rd)]
Length=853
Score = 493 bits (1268), Expect = 9e-165
Identities = 300/765 (39%), Positives = 429/765 (56%), Gaps = 77/765 (10%)
Query 47 KAPLLKPLQVYTSDNQLIAEYGGKLSVPVEYNQIPPTFIHAFLAAEDSSFFEHSGISFKG 106
K+ L +P+Q+YT+D +LI E G + +PV+ +P I AFLA EDS F++H G+ G
Sbjct 30 KSELQQPMQIYTADGKLIGEVGEQRRIPVKLADVPQRLIDAFLATEDSRFYDHHGLDPIG 89
Query 107 LGRALSETVTGSNVQTGGSTITMQVAKNYYLSPERTLKRKLTEIFLARKIEQNLTKQEIL 166
+ RAL V+ G STIT Q+A+N++L+ E+T+ RK E LA +IE L KQEIL
Sbjct 90 IARALFVAVSNGGASQGASTITQQLARNFFLTSEKTIIRKAREAVLAVEIENTLNKQEIL 149
Query 167 SLYVNKIFLGKNAYGIAAAAKIYYNKTLDQLSIAEMAMISGLPKAPSKYNPVVNPERALE 226
LY+NKIFLG +YG+AAAA+ Y+ K+L++L+++EMA+I+GLPKAPS NP+ + +R+ E
Sbjct 150 ELYLNKIFLGYRSYGVAAAAQTYFGKSLNELTLSEMAIIAGLPKAPSTMNPLYSLKRSEE 209
Query 227 RRNWILGRMLQLGYINQTQYQQAVAEPINLDMPDRGVSNRYPYIGEMVRAELVEKFGEQ- 285
RRN +L RML YI++ +Y A+ EPI R Y+ EMVR E+V +FGE+
Sbjct 210 RRNVVLSRMLDEKYISKEEYDAALKEPIVASYHGAKFEFRADYVTEMVRQEMVRRFGEEN 269
Query 286 AVDSGYKVYTTINSQRQAYAEQSVQDGLEAYDRRHGWRGA--------EAHDKP-----L 332
A SGYKV+TT+ S+ QA A+++V++ L YD RHG+RG A D L
Sbjct 270 AYTSGYKVFTTVLSKDQAEAQKAVRNNLIDYDMRHGYRGGAPLWQKNEAAWDNDRIVGFL 329
Query 333 RNFIPYANTFPAEVIKVGNNSFDALMQDGKTVTVPWSGMSWARRYRNANSVGESPSRASQ 392
R PA VI + D L+ G+ +T+ + M W R N VGE
Sbjct 330 RKLPDSEPFIPAAVIGIVKGGADILLASGEKMTLSTNAMRWTGR-SNPVKVGE------- 381
Query 393 IVKVKDIVRLRPNGDKSAWSLVQIPKVQGQLIALNPNDGSIEALVGGYNFYQSKFNRALQ 452
+ + R NG+ W L QIP L++LN ++G+IEA+VGG+++ QSKFNRA Q
Sbjct 382 ----QIWIHQRANGE---WQLGQIPAANSALVSLNSDNGAIEAVVGGFSYEQSKFNRATQ 434
Query 453 GWRQPGSTIKPFIYALALERGMTPYTMVNDSPISIGR-----WSPKNSDGRYLGMIPLRR 507
Q GS+IKPFIYA ALE+G+T +++ DSPISI + W PKNS RY G + LR
Sbjct 435 SLVQVGSSIKPFIYAAALEKGLTLSSVLQDSPISIQKPGQKMWQPKNSPDRYDGPMRLRV 494
Query 508 ALYLSRNTVSVRLLQSVGVERARQLLMDFGLQENQIPRNFTIALGTPQVLPIQMATGYAT 567
L S+N +++R +Q+ G++ + L FG + +Q + +ALG P++MA YA
Sbjct 495 GLGQSKNIIAIRAIQTAGIDFTAEFLQRFGFKRDQYFASEALALGAASFTPLEMARAYAV 554
Query 568 FANGGYRIQPHFIRRIEDAYGNVIFETKPEYACIPC-------------IN--------- 605
F NGG+ I+P+ I +I+D G +F P+ ACI C IN
Sbjct 555 FDNGGFLIEPYIIEKIQDNTGKDLFIANPKIACIECNDIPVIYGETKDKINGFANIPLGE 614
Query 606 --------ETNNTETEIKPQT-PDDEVIEVNNQSL-DEAKTLVSPAKTNPDNNNYRQAQR 655
TN E + +P+T P+ ++ N +L ++A L++ AK Y A R
Sbjct 615 NALKPTDDSTNGEELDQQPETVPELPELQSNMTALKEDAIDLMAAAKNASSKIEY--APR 672
Query 656 ILKSSSAYDMANILRDVILHGTG--------RAALKIGRDDLGGKTGTTNDAKDAWFAGF 707
++ A+ + + L I G R A I R D+GGKTGTTN +K AW+AGF
Sbjct 673 VISGELAFLIRSALNTAIYGEQGLDWKGTSWRIAQSIKRSDIGGKTGTTNSSKVAWYAGF 732
Query 708 NGKLVAVAWVGF-DQPTTLGRREYGGVAALPIWTNFMDQSLKGTP 751
LV +VGF D LGR E G A+P W +M +L P
Sbjct 733 GANLVTTTYVGFDDNKRVLGRGEAGAKTAMPAWITYMKTALSDKP 777
>P39793 Penicillin-insensitive transglycosylase / Penicillin-sensitive
transpeptidase [Bacillus subtilis (strain 168)]
Length=914
Score = 176 bits (445), Expect = 3e-48
Identities = 109/303 (36%), Positives = 170/303 (56%), Gaps = 22/303 (7%)
Query 13 FFLLILMVLVSVPMGFYGMYLYIAPSLPEMSSLKKAPLLKPLQ--VYTSDNQLIAEYGGK 70
F LLIL VL G G + A + + SL ++ L P +Y + + IAE G +
Sbjct 39 FTLLILFVL-----GVVGGAVTFAVMVSDAPSLDESKLKTPYSSTIYDKNGKEIAEVGAE 93
Query 71 LSVPVEYNQIPPTFIHAFLAAEDSSFFEHSGISFKGLGRALSETVTGSNVQTGGSTITMQ 130
V ++IP AF+A ED+ F+EH GI +G AL GGSTIT Q
Sbjct 94 KRTYVSIDEIPDVVKEAFIATEDARFYEHHGIDPVRIGGALVANFKDGFGAEGGSTITQQ 153
Query 131 VAKNYYLSPERTLKRKLTEIFLARKIEQNLTKQEILSLYVNKIFLGKNAYGIAAAAKIYY 190
V KN LS ++TLKRK+ E++L+ ++E+N +K EIL +Y+N+I+ AYGI AA+ ++
Sbjct 154 VVKNSLLSHQKTLKRKVQEVWLSIQLERNYSKDEILEMYLNRIYFSPRAYGIGKAAEEFF 213
Query 191 NKT-LDQLSIAEMAMISGLPKAPSKYNPVVNPERALERRNWILGRMLQLGYINQTQYQQA 249
T L +L++ + A ++G+P++P+ YNPV NP++A +RRN +L M + G+I+ +QY +A
Sbjct 214 GVTDLSKLTVEQAATLAGMPQSPTAYNPVKNPDKAEKRRNIVLSLMKKQGFISDSQYNKA 273
Query 250 VAEPINLDMPDRGV----------SNRYPYIGEMVRAELVEKFGEQAVDSGYKVYTTINS 299
+ + D GV +N+Y E V E+ EK G K+YTT+++
Sbjct 274 K----KVAVKDEGVVSQKEYEKASTNKYSAFVEEVMKEIDEKSDVDPSADGLKIYTTLDT 329
Query 300 QRQ 302
+ Q
Sbjct 330 KAQ 332
Score = 95.5 bits (236), Expect = 6e-23
Identities = 80/324 (25%), Positives = 138/324 (43%), Gaps = 78/324 (24%)
Query 419 VQGQLIALNPNDGSIEALVGGYNFYQSKFNRALQGWRQPGSTIKPFI-YALALE-RGMTP 476
+QG + L+ +G + A+ G N FN A Q QPGSTIKP + Y +E + +
Sbjct 350 MQGGVTLLDTKNGEVRAIGAGRNQPVGGFNYATQTKAQPGSTIKPILDYGPVIENKKWST 409
Query 477 YTMVNDSPISIGRWSP-KNSDGRYLGMIPLRRALYLSRNTVSVRLLQSVGVERARQLL-- 533
Y ++DS + P ++ D +YLG I +R AL SRN +++ Q+VG + A
Sbjct 410 YEQIDDSAYTYSNGKPIRDWDRKYLGPISMRYALAQSRNIPALKAFQAVGKDTAVDFANG 469
Query 534 MDFGLQENQIPRNFTIA--LGTPQVLPIQMATGYATFANGGYRIQPHFIRRIEDAYGNVI 591
+ GL ++ + ++I G V P+ MA Y+ F N G +PHF++ IE
Sbjct 470 LGLGLTKDNVTEAYSIGGFGGNDGVSPLTMAGAYSAFGNNGTYNEPHFVKSIE------- 522
Query 592 FETKPEYACIPCINETNNTETEIKPQTPDDEVIEVNNQSLDEAKTLVSPAKTNPDNNNYR 651
+ T+ ++ P+
Sbjct 523 --------------FNDGTKLDLTPK---------------------------------- 534
Query 652 QAQRILKSSSAYDMANILRDVILHGTGRAALKIGRDDLGGKTGTTN-------------- 697
++ + +A+ + ++L+ + GTG+ A ++ ++ GKTGTTN
Sbjct 535 -SKSAMSDYTAFMITDMLKTAVKTGTGQLA-QVPGVEVAGKTGTTNFDDNEVKRYNIASG 592
Query 698 DAKDAWFAGFNGKLVAVAWVGFDQ 721
A+D+WF G+ + A W G +
Sbjct 593 GARDSWFVGYTPQYTAAVWTGMGE 616
Score = 20.4 bits (41), Expect = 7.8
Identities = 12/31 (39%), Positives = 17/31 (55%), Gaps = 2/31 (6%)
Query 743 MDQSLKGTPSAWVRFDKNAK--APLSREKPT 771
+D+S TP + +DKN K A + EK T
Sbjct 66 LDESKLKTPYSSTIYDKNGKEIAEVGAEKRT 96
>P38050 Penicillin-insensitive transglycosylase / Penicillin-sensitive
transpeptidase [Bacillus subtilis (strain 168)]
Length=714
Score = 169 bits (429), Expect = 8e-47
Identities = 85/242 (35%), Positives = 145/242 (60%), Gaps = 3/242 (1%)
Query 74 PVEYNQIPPTFIHAFLAAEDSSFFEHSGISFKGLGRALSETVTGSNVQTGGSTITMQVAK 133
PV N+IP AF+A ED F+EH GI K +GRA+ + GGSTIT Q+AK
Sbjct 69 PVSINEIPKQVREAFIAVEDKRFYEHHGIDAKSVGRAVYRDILAGGKVEGGSTITQQLAK 128
Query 134 NYYLSPERTLKRKLTEIFLARKIEQNLTKQEILSLYVNKIFLGKNAYGIAAAAKIYYNKT 193
N +L+ ++T RK E+ +A +E++ +K ++L +Y+N+++ G YGI AA+ Y+NK
Sbjct 129 NIFLTHDKTFLRKTKEVIIAINLERDYSKDKLLEMYLNQLYFGHGVYGIQAASHYYFNKE 188
Query 194 LDQLSIAEMAMISGLPKAPSKYNPVVNPERALERRNWILGRMLQLGYINQTQYQQAVAEP 253
+ L+++E A+++ +PKAPS Y+P+++P++ ERR+ ILG M GYI+ + A
Sbjct 189 VKDLTVSEGAVLAAIPKAPSTYSPILHPDKNKERRDTILGMMNDQGYISAKEAVTAQGRT 248
Query 254 INLDMPDRGVSNRYPYIGEMVRAELVEKF---GEQAVDSGYKVYTTINSQRQAYAEQSVQ 310
+ L + + + + ++V E +K+ GEQ + GY + ++S+ Q A Q ++
Sbjct 249 LGLHVKKQSETPWFDSYIDLVIKEAEDKYSISGEQLLQGGYTIKVPLDSKLQKTAYQVMK 308
Query 311 DG 312
+G
Sbjct 309 EG 310
Score = 111 bits (277), Expect = 5e-28
Identities = 91/313 (29%), Positives = 136/313 (43%), Gaps = 72/313 (23%)
Query 420 QGQLIALNPNDGSIEALVGGYNFYQSKFNRALQGWRQPGSTIKPF-IYALAL-ERGMTPY 477
+G + +N G +EA +GG ++ +NR + RQPGST KP +Y A+ E+ PY
Sbjct 321 EGSAVFINNKTGGVEAAIGGRDYTSKGYNR-VTAVRQPGSTFKPLAVYGPAMQEKKFKPY 379
Query 478 TMVNDSPISIGRWSPKNSDGRYLGMIPLRRALYLSRNTVSVRLLQSVGVERARQLLMDFG 537
+++ D S G ++PKN D RY G + + A+ S+N +V L +GVE + L G
Sbjct 380 SLLKDELQSYGDYTPKNYDSRYEGEVTMSDAITYSKNAPAVWTLNEIGVETGKSYLKANG 439
Query 538 LQENQIP-RNFTIALGTPQ--VLPIQMATGYATFANGGYRIQPHFIRRIEDAYGNVIFET 594
+ IP +ALG + V P+Q+A + TFA G +P FI I D G I +
Sbjct 440 I---DIPDEGLALALGGLEKGVSPLQLAGAFHTFAANGTYTEPFFISSIIDEDGETIADH 496
Query 595 KPEYACIPCINETNNTETEIKPQTPDDEVIEVNNQSLDEAKTLVSPAKTNPDNNNYRQAQ 654
K +E K + S N R Q
Sbjct 497 K------------------------------------EEGKRVFS---KQTSWNMTRMLQ 517
Query 655 RILKSSSAYDMANILRDVILHGTGRAALKIGRDDLGGKTGTTN------DAKDAWFAGFN 708
+++K +A HG DL GKTG+T+ KDAWFAG+
Sbjct 518 QVVKKGTA-------TSGTYHG-----------DLAGKTGSTSYTGVSGATKDAWFAGYT 559
Query 709 GKLVAVAWVGFDQ 721
K+ W+G+D+
Sbjct 560 PKITGAVWMGYDK 572
>P70997 Penicillin-insensitive transglycosylase / Penicillin-sensitive
transpeptidase [Bacillus subtilis (strain 168)]
Length=691
Score = 167 bits (424), Expect = 3e-46
Identities = 99/266 (37%), Positives = 153/266 (58%), Gaps = 7/266 (3%)
Query 56 VYTSDNQLIAEYG-GKLSVPVEYNQIPPTFIHAFLAAEDSSFFEHSGISFKGL-GRALSE 113
+Y SD + E G+ V + PT + A +A ED +F++H G +K + G AL++
Sbjct 57 LYASDGSKLGETNYGEKRYWVPLKDMNPTIVKATVAIEDQNFYDHHGFDYKRMAGAALAD 116
Query 114 TVTGSNVQTGGSTITMQVAKNYYLSPERTLKRKLTEIFLARKIEQNLTKQEILSLYVNKI 173
+ VQ G STIT Q A+N YL ++T KRK E F ++EQN +K EIL Y+N I
Sbjct 117 LKAFAKVQ-GASTITQQYARNLYLEHDKTWKRKWNEAFYTIRLEQNYSKDEILEGYLNTI 175
Query 174 FLGKNAYGIAAAAKIYYNKTLDQLSIAEMAMISGLPKAPSKYNPVVNPERALERRNWILG 233
+ G AYGI AA+++Y+ K L+ AE A+++G+PK PS Y+P VN +A ER+ I+
Sbjct 176 YYGHGAYGIEAASRLYFGKHAKNLTDAEAALLAGIPKGPSGYSPYVNETKAKERQKTIVR 235
Query 234 RMLQLGYINQTQYQQAVAEPINLDMPDRGVSNR-YPYIGEMVRAELVEKFG---EQAVDS 289
M + I+Q + + + EP++ ++ VS R PY + EL +K G EQ S
Sbjct 236 MMEKQQMISQKKADELIKEPLSYQPLNKQVSKRKAPYFYDNAMRELEKKLGMTREQIETS 295
Query 290 GYKVYTTINSQRQAYAEQSVQDGLEA 315
G VYTT++ + Q AE+++ + + A
Sbjct 296 GLNVYTTVDKRMQRIAEETITETVNA 321
Score = 143 bits (361), Expect = 3e-38
Identities = 106/344 (31%), Positives = 158/344 (46%), Gaps = 67/344 (19%)
Query 419 VQGQLIALNPNDGSIEALVGGYNFYQSKFNRALQGWRQPGSTIKPFIYALALERGMTPYT 478
+Q A++P G++ ALVGG ++ +S F+R Q RQP STIKP +Y A++ G TP T
Sbjct 325 IQVGFSAIDPRTGNVLALVGGRDYQKSPFDRTTQAKRQPASTIKPLLYYKAIQSGFTPVT 384
Query 479 MVNDSPISI------GRWSPKNSDGRYLGM-IPLRRALYLSRNTVSVRLLQSVGVERARQ 531
++ +SP N +G Y I L +AL LS N +V+ +G + +
Sbjct 385 LMKSEETEFQIDAKGETYSPSNYNGYYANKPITLLQALALSDNIYAVKTHLFLGTNKLVK 444
Query 532 LLMDFGLQENQIPRNFTIALGTPQVLPIQMATGYATFANGGYRIQPHFIRRIEDAYGNVI 591
+FG+ + + ++ALGT V PI+M YA ANGG +I+P FI R+ DA G+V+
Sbjct 445 TAKEFGITAH-LQALPSLALGTEPVRPIEMVNAYAMLANGGKKIEPTFISRVTDAAGHVL 503
Query 592 FETKPEYACIPCINETNNTETEIKPQTPDDEVIEVNNQSLDEAKTLVSPAKTNPDNNNYR 651
+E ++ Q LDE V+ +
Sbjct 504 YENPNQH-----------------------------KQVLDEKAAFVTAS---------- 524
Query 652 QAQRILKSSSAYDMANILRDVILHG----TGRAALKIGRDDLGGKTGTTNDAKDAWFAGF 707
M + D+ L+G TGR GK+GTT + D+W GF
Sbjct 525 -------------MMTGMFDIDLNGYTSVTGRTIANRLTRTYAGKSGTT--SADSWMIGF 569
Query 708 NGKLVAVAWVGFDQPTTLGRREYGGVAALPIWTNFMDQSLKGTP 751
N KL A W G+D+ +T+ E A IW +FM+ +LKG P
Sbjct 570 NPKLAAGVWTGYDKNSTIDSVEEKSYAK-TIWADFMEDALKGEP 612
>P02919 Penicillin-insensitive transglycosylase / Penicillin-sensitive
transpeptidase [Escherichia coli (strain K12)]
Length=844
Score = 157 bits (397), Expect = 2e-42
Identities = 90/262 (34%), Positives = 146/262 (56%), Gaps = 6/262 (2%)
Query 63 LIAEYGGKLSVPVEYNQIPPTFIHAFLAAEDSSFFEHSGISFKGLGRALSETVTGSNVQT 122
+I+ G+ + V + P + LA ED F+EH GIS +GRA+ +T
Sbjct 204 MISSPNGEQRLFVPRSGFPDLLVDTLLATEDRHFYEHDGISLYSIGRAVLANLTAGRTVQ 263
Query 123 GGSTITMQVAKNYYLSPERTLKRKLTEIFLARKIEQNLTKQEILSLYVNKIFLGKNA--- 179
G ST+T Q+ KN +LS ER+ RK E ++A ++ +K IL LY+N+++LG++
Sbjct 264 GASTLTQQLVKNLFLSSERSYWRKANEAYMALIMDARYSKDRILELYMNEVYLGQSGDNE 323
Query 180 -YGIAAAAKIYYNKTLDQLSIAEMAMISGLPKAPSKYNPVVNPERALERRNWILGRMLQL 238
G A+ Y+ + +++LS+ + A++ G+ K S YNP NP+ ALERRN +L + Q
Sbjct 324 IRGFPLASLYYFGRPVEELSLDQQALLVGMVKGASIYNPWRNPKLALERRNLVLRLLQQQ 383
Query 239 GYINQTQYQQAVAEPINLDMPDRGVSNRYPYIGEMVRAELVEKFGEQAVD-SGYKVYTTI 297
I+Q Y A P+ + P GV + P ++VR EL K G++ D SG K++TT
Sbjct 384 QIIDQELYDMLSARPLGV-QPRGGVISPQPAFMQLVRQELQAKLGDKVKDLSGVKIFTTF 442
Query 298 NSQRQAYAEQSVQDGLEAYDRR 319
+S Q AE++ +G+ A ++
Sbjct 443 DSVAQDAAEKAAVEGIPALKKQ 464
Score = 85.1 bits (209), Expect = 1e-19
Identities = 85/340 (25%), Positives = 134/340 (39%), Gaps = 69/340 (20%)
Query 415 QIPKVQGQLIALNPNDGSIEALVGGYNFYQSKFNRALQGWRQPGSTIKPFIYALALERGM 474
++ ++ ++ ++ G + A+VGG + +NRA+Q R GS KP Y AL +
Sbjct 466 KLSDLETAIVVVDRFSGEVRAMVGGSEPQFAGYNRAMQARRSIGSLAKPATYLTALSQPK 525
Query 475 TPY--TMVNDSPISIGR-----WSPKNSDGRYLGMIPLRRALYLSRNTVSVRLLQSVGVE 527
T + D+PI++ + WSP+N D RY E
Sbjct 526 IYRLNTWIADAPIALRQPNGQVWSPQNDDRRYS--------------------------E 559
Query 528 RARQLLMDFGLQENQIPR-NFTIALGTPQVLPIQMATGYATFANGGYRIQPHFIRRIEDA 586
R +L+D + +P N +ALG P V + G
Sbjct 560 SGRVMLVDALTRSMNVPTVNLGMALGLPAVTETWIKLGVP-------------------- 599
Query 587 YGNVIFETKPEYACIPCINETNNTETEIKPQTPDDEVIEVNNQSLDEAKTLVSPAKTNPD 646
K + +P + T I+ + N++ A V
Sbjct 600 --------KDQLHPVPAMLLGALNLTPIEVAQAFQTIASGGNRAPLSALRSVIAEDGKVL 651
Query 647 NNNYRQAQRILKSSSAYDMANILRDVILHGTGRA-ALKIGRDDLGGKTGTTNDAKDAWFA 705
++ QA+R + + +AY ++ V+ GTGR K L GKTGTTN+ D WFA
Sbjct 652 YQSFPQAERAVPAQAAYLTLWTMQQVVQRGTGRQLGAKYPNLHLAGKTGTTNNNVDTWFA 711
Query 706 GFNGKLVAVAWVGFD--QPTTLGRREYGGVAALPIWTNFM 743
G +G V + WVG D QPT L YG A+ I+ ++
Sbjct 712 GIDGSTVTITWVGRDNNQPTKL----YGASGAMSIYQRYL 747
Score = 22.7 bits (47), Expect = 1.5
Identities = 13/35 (37%), Positives = 15/35 (43%), Gaps = 2/35 (6%)
Query 338 YANTFPAEVIKVGNNSFDALMQ--DGKTVTVPWSG 370
Y N A NN+ D DG TVT+ W G
Sbjct 690 YPNLHLAGKTGTTNNNVDTWFAGIDGSTVTITWVG 724
>P40750 Penicillin-insensitive transglycosylase / Penicillin-sensitive
transpeptidase [Bacillus subtilis (strain 168)]
Length=624
Score = 151 bits (382), Expect = 3e-41
Identities = 89/280 (32%), Positives = 145/280 (52%), Gaps = 10/280 (4%)
Query 45 LKKAPLLKPLQVYTSDNQLIAEYGG--KLSVPVEYNQIPPTFIHAFLAAEDSSFFEHSGI 102
LK L++ +Y D L++E + V V +N+IP FL +ED F+EH G
Sbjct 47 LKDISLVQNSYMYDRDGSLVSEIVSDHENRVLVPFNKIPEEVKQIFLTSEDRHFYEHKGF 106
Query 103 SFKGLGRALSETVTGSNVQTGGSTITMQVAKNYYLSPERTLKRKLTEIFLARKIEQNLTK 162
F G+ RA + V + G STIT Q+++N YLS ER+ RKLTE+ + ++E+ TK
Sbjct 107 DFMGMVRATASNVKDKKIDQGASTITQQLSRNLYLSHERSFSRKLTELAYSYQLEKKYTK 166
Query 163 QEILSLYVNKIFLGKNAYGIAAAAKIYYNKTLDQLSIAEMAMISGLPKAPSKYNPVVNPE 222
EIL Y+N I+ YG+ +AA+ Y++K L L++ EMA I +P P+ Y+P+ + +
Sbjct 167 NEILEAYLNTIYFNNGVYGVGSAAQFYFSKPLKSLTVGEMAFICAIPNNPTLYDPLKHFD 226
Query 223 RALERRNWILGRMLQLGYINQTQYQQAVAEPINLDMPDRGVSNRYPYIGEMVRAELV--- 279
R+ +L + G I + ++AV + I LD+ R ++YP V E
Sbjct 227 YTKSRQERLLKGLKDAGVITDKELKKAVKQKIKLDVEKR--EDKYPDYVSYVNDEFTQLV 284
Query 280 ---EKFGEQAVDSGYKVYTTINSQRQAYAEQSVQDGLEAY 316
E F ++ + K I ++ A ++DG++ Y
Sbjct 285 SESEGFDKRLQKASGKQKEKIENELSARVSTLMKDGVKIY 324
Score = 106 bits (265), Expect = 1e-26
Identities = 83/313 (27%), Positives = 132/313 (42%), Gaps = 63/313 (20%)
Query 419 VQGQLIALNPNDGSIEALVGGYNFYQSKFNRALQGWRQPGSTIKPFI-YALALER-GMTP 476
VQG +N I AL GG N+ + FNRA Q +RQPGS+IKP + Y +E+ G T
Sbjct 348 VQGGAAVINHQTHQIIALSGGKNYQKYDFNRAYQAYRQPGSSIKPLLDYGPYIEQTGATT 407
Query 477 YTMVNDSPISIGRWSPKNSDGRYLGMIPLRRALYLSRNTVSVRLLQSVGVERARQLLMDF 536
+ ++ S + P+N + R G + L A S NT ++R+L VG+++A + +
Sbjct 408 SSTIDASKFCSKDYCPQNYNNRTYGTVTLDTAFKNSYNTPAIRMLDRVGIQKAFSYIEPY 467
Query 537 GLQENQIPRNFTI--ALG--TPQVLPIQMATGYATFANGGYRIQPHFIRRIEDAYGNVIF 592
+ + ++ + ALG T + P++M Y TF N G H I ++ D G ++
Sbjct 468 HFAK-LVDSDYLLPAALGGFTNGMTPLEMTKAYTTFGNSGSYTPSHAITKVTDLKGKTLY 526
Query 593 ETKPEYACIPCINETNNTETEIKPQTPDDEVIEVNNQSLDEAKTLVSPAKTNPDNNNYRQ 652
+ ++ T + +TN
Sbjct 527 K-------------------------------------WNDKATQIFSVRTN-------- 541
Query 653 AQRILKSSSAYDMANILRDVILHGTGRAALKIGRDDLGGKTGTTNDAKDAWFAGFNGKLV 712
+ ++ V+ GTG+ A +GGKTGT+ND D WF G
Sbjct 542 ----------MQLKKLMSSVVKSGTGKKAY-FNAPYIGGKTGTSNDYHDMWFVGLTDTYT 590
Query 713 AVAWVGFDQPTTL 725
WVG D PT++
Sbjct 591 MGVWVGKDTPTSV 603
Lambda K H a alpha
0.317 0.134 0.395 0.792 4.96
Gapped
Lambda K H a alpha sigma
0.267 0.0410 0.140 1.90 42.6 43.6
Effective search space used: 10460975
Database: 3bd51ba20115c9046080788ca1e1a0ff.SwissProt.fasta
Posted date: May 19, 2024 8:45 PM
Number of letters in database: 14,341
Number of sequences in database: 18
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Neighboring words threshold: 11
Window for multiple hits: 40
Loading
Data ...
