BLASTP 2.12.0+
Reference: Stephen F. Altschul, Thomas L. Madden, Alejandro A.
Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J.
Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of
protein database search programs", Nucleic Acids Res. 25:3389-3402.
Reference for composition-based statistics: Alejandro A. Schaffer,
L. Aravind, Thomas L. Madden, Sergei Shavirin, John L. Spouge, Yuri
I. Wolf, Eugene V. Koonin, and Stephen F. Altschul (2001),
"Improving the accuracy of PSI-BLAST protein database searches with
composition-based statistics and other refinements", Nucleic Acids
Res. 29:2994-3005.
Database: d6e2e64d3ceb3ce2f46b472c7b3e9104.SwissProt.fasta
23 sequences; 9,642 total letters
Query= ACIAD3292
Length=410
Score E
Sequences producing significant alignments: (Bits) Value
D0CCT2 Chloramphenicol resistance protein CraA [Acinetobacter bau... 638 0.0
E0T2N0 Multidrug transporter MdfA [Edwardsiella tarda (strain FL6... 315 7e-108
D0ZHC6 Multidrug transporter MdfA [Edwardsiella tarda (strain EIB... 315 7e-108
A9R4E0 Multidrug transporter MdfA [Yersinia pestis bv. Antiqua (s... 314 2e-107
D5B5U5 Multidrug transporter MdfA [Yersinia pestis (strain Z176003)] 314 2e-107
D0JKF6 Multidrug transporter MdfA [Yersinia pestis (strain D106004)] 314 2e-107
D0JUX5 Multidrug transporter MdfA [Yersinia pestis (strain D182038)] 314 2e-107
P0AEY9 Multidrug transporter MdfA [Escherichia coli O6:H1 (strain... 311 3e-106
P0AEZ0 Multidrug transporter MdfA [Escherichia coli O157:H7] 311 3e-106
P0AEY8 Multidrug transporter MdfA [Escherichia coli (strain K12)] 311 3e-106
C5BC70 Multidrug transporter MdfA [Edwardsiella ictaluri (strain ... 310 1e-105
Q323U7 Multidrug transporter MdfA [Shigella boydii serotype 4 (st... 308 3e-105
Q7CP73 Multidrug resistance protein MdtM [Salmonella typhimurium ... 277 5e-93
Q8XFG0 Multidrug resistance protein MdtM [Salmonella typhi] 277 5e-93
P39386 Multidrug resistance protein MdtM [Escherichia coli (strai... 267 4e-89
Q8XB84 Multidrug resistance protein MdtM [Escherichia coli O157:H7] 267 5e-89
P37597 Inner membrane transport protein YdhC [Escherichia coli (s... 118 1e-32
P28246 Bicyclomycin resistance protein [Escherichia coli (strain ... 101 8e-27
P31462 Multidrug resistance protein MdtL [Escherichia coli (strai... 96.7 4e-25
P32482 Chloramphenicol resistance protein [Pseudomonas aeruginosa] 89.7 1e-22
P96712 Multidrug resistance protein 3 [Bacillus subtilis (strain ... 85.1 6e-21
P31474 Probable transport protein HsrA [Escherichia coli (strain ... 80.5 2e-19
S0DS64 Trichosetin biosynthesis cluster MFS transporter [Gibberel... 79.0 6e-19
>D0CCT2 Chloramphenicol resistance protein CraA [Acinetobacter
baumannii (strain ATCC 19606 / DSM 30007 / JCM 6841 / CCUG
19606 / CIP 70.34 / NBRC 109757 / NCIMB 12457 / NCTC 12156 /
81)]
Length=413
Score = 638 bits (1646), Expect = 0.0
Identities = 323/407 (79%), Positives = 356/407 (87%), Gaps = 0/407 (0%)
Query 1 MQNVRTTTLNRTTLMFPLALVLFEFAVYIGNDLIQPAMLAITQDFAVSATWAPSSMSFYL 60
M+N++TT LNRTTLMFPLALVLFEFAVYIGNDLIQPAMLAIT+DF VSATWAPSSMSFYL
Sbjct 5 MKNIQTTALNRTTLMFPLALVLFEFAVYIGNDLIQPAMLAITEDFGVSATWAPSSMSFYL 64
Query 61 LGGACVAWLLGPLSDRLGRKRVLLFGVLFFALCCLLILLTHNMAQFLALRFLQGIGLSVI 120
LGGA VAWLLGPLSDRLGRK+VLL GVLFFALCC LILLT + FL LRFLQGIGLSVI
Sbjct 65 LGGASVAWLLGPLSDRLGRKKVLLSGVLFFALCCFLILLTRQIEHFLTLRFLQGIGLSVI 124
Query 121 TAVGYAAIQETFEERDAIKVMALMANISLLAPLLGPVLGAFLIDYVSWHWGFVAIATLAG 180
+AVGYAAIQE F ERDAIKVMALMANISLLAPLLGPVLGAFLIDYVSWHWGFVAIA LA
Sbjct 125 SAVGYAAIQENFAERDAIKVMALMANISLLAPLLGPVLGAFLIDYVSWHWGFVAIALLAL 184
Query 181 LSWFGLKAKMPSQQHSVTRQPFVYLFDDFKKIYLDKRFLGLSLGLPLVGMPLMLWIALSP 240
LSW GLK +MPS + SVT+QPF YLFDDFKK++ +++FLGL+L LPLVGMPLMLWIALSP
Sbjct 185 LSWVGLKKQMPSHKVSVTKQPFSYLFDDFKKVFSNRQFLGLTLALPLVGMPLMLWIALSP 244
Query 241 VMLVDELKFSSVQYGLAQFPIFMGLILGNIVLIKIIDRFPLGKTILMGLPIMLVGTLVLL 300
++LVDELK +SVQYGLAQFP+F+GLI+GNIVLIKIIDR LGKT+L+GLPIML GTL+L+
Sbjct 245 IILVDELKLTSVQYGLAQFPVFLGLIVGNIVLIKIIDRLALGKTVLIGLPIMLTGTLILI 304
Query 301 VGAIWQDYLAVCLLVGMTLISFGEGISFSVIYRFALMSSPVAKGTVAAAVSMLLMFSFFI 360
+G +WQ YL CLL+GMTLI FGEGISFSV+YRFALMSS V+KGTVAAAVSMLLM SFF
Sbjct 305 LGVVWQAYLIPCLLIGMTLICFGEGISFSVLYRFALMSSEVSKGTVAAAVSMLLMTSFFA 364
Query 361 MIELVRELYVHFHVLAFSLSCVVLITLWFLLPRLMLKQEMAIRHTHD 407
MIELVR LY FH+ AF LS I LWF PRL LK+EM R D
Sbjct 365 MIELVRYLYTQFHLWAFVLSAFAFIALWFTQPRLALKREMQERVAQD 411
>E0T2N0 Multidrug transporter MdfA [Edwardsiella tarda (strain
FL6-60)]
Length=410
Score = 315 bits (808), Expect = 7e-108
Identities = 175/405 (43%), Positives = 254/405 (63%), Gaps = 9/405 (2%)
Query 1 MQNVRTTT--LNRTTLMFPLALVLFEFAVYIGNDLIQPAMLAITQDFAVSATWAPSSMSF 58
MQN ++T L R L+FPL LVL+EFA YIGND+IQP ML++ Q F V +W P+SM+
Sbjct 1 MQNRLSSTRRLGRRALLFPLCLVLYEFATYIGNDMIQPGMLSVVQTFGVDESWVPTSMTA 60
Query 59 YLLGGACVAWLLGPLSDRLGRKRVLLFGVLFFALCCLLILLTHNMAQFLALRFLQGIGLS 118
YL GG + WLLGP+SDR+GR+ V+L G L+FA+ CL ILLT+++ QF +RFLQGI L
Sbjct 61 YLAGGMFLQWLLGPISDRIGRRPVMLTGTLYFAVTCLAILLTNSIEQFTLMRFLQGISLC 120
Query 119 VITAVGYAAIQETFEERDAIKVMALMANISLLAPLLGPVLGAFLIDYVSWHWGFVAIATL 178
I AVGYAAIQE+FEE IK+ ALMAN++L+APLLGP+ GA + W F+ A L
Sbjct 121 FIGAVGYAAIQESFEESVCIKITALMANVALIAPLLGPLAGAAWVHLFPWEGMFILFAAL 180
Query 179 AGLSWFGLKAKMPSQQHSVTRQ----PFVYLFDDFKKIYLDKRFLGLSLGLPLVGMPLML 234
+ L++ GL MP + TR+ L D+ + +KRFLG +L +PL+
Sbjct 181 SLLAFLGLYKAMP---ETATRRGETLSLSALGHDYALVLKNKRFLGGALACGFASLPLLA 237
Query 235 WIALSPVMLVDELKFSSVQYGLAQFPIFMGLILGNIVLIKIIDRFPLGKTILMGLPIMLV 294
WIA SPV+++ SS YG+ Q PIF LILGN L ++ R P+ + I +G M+
Sbjct 238 WIAQSPVIIISGEGLSSYDYGMLQVPIFGMLILGNFTLARLSGRRPVRRLIQLGAWPMVG 297
Query 295 GTLVLLVGAIWQDYLAVCLLVGMTLISFGEGISFSVIYRFALMSSPVAKGTVAAAVSMLL 354
G + V ++ + + + G++L +FG G++ + +YR L SS ++KGTV+AA+ M+
Sbjct 298 GLAIAAVSTLYSAHAYLWMTAGLSLYAFGIGLANAGLYRLTLFSSTMSKGTVSAAMGMIS 357
Query 355 MFSFFIMIELVRELYVHFHVLAFSLSCVVLITLWFLLPRLMLKQE 399
MF + + IE+ + ++ AF+L ++ LW L LML+ +
Sbjct 358 MFIYTLGIEVGKHAWLLGGNGAFNLFNLISGLLWLALVALMLRDK 402
>D0ZHC6 Multidrug transporter MdfA [Edwardsiella tarda (strain
EIB202)]
Length=410
Score = 315 bits (808), Expect = 7e-108
Identities = 175/405 (43%), Positives = 254/405 (63%), Gaps = 9/405 (2%)
Query 1 MQNVRTTT--LNRTTLMFPLALVLFEFAVYIGNDLIQPAMLAITQDFAVSATWAPSSMSF 58
MQN ++T L R L+FPL LVL+EFA YIGND+IQP ML++ Q F V +W P+SM+
Sbjct 1 MQNRLSSTRRLGRRALLFPLCLVLYEFATYIGNDMIQPGMLSVVQTFGVDESWVPTSMTA 60
Query 59 YLLGGACVAWLLGPLSDRLGRKRVLLFGVLFFALCCLLILLTHNMAQFLALRFLQGIGLS 118
YL GG + WLLGP+SDR+GR+ V+L G L+FA+ CL ILLT+++ QF +RFLQGI L
Sbjct 61 YLAGGMFLQWLLGPISDRIGRRPVMLTGTLYFAVTCLAILLTNSIEQFTLMRFLQGISLC 120
Query 119 VITAVGYAAIQETFEERDAIKVMALMANISLLAPLLGPVLGAFLIDYVSWHWGFVAIATL 178
I AVGYAAIQE+FEE IK+ ALMAN++L+APLLGP+ GA + W F+ A L
Sbjct 121 FIGAVGYAAIQESFEESVCIKITALMANVALIAPLLGPLAGAAWVHLFPWEGMFILFAAL 180
Query 179 AGLSWFGLKAKMPSQQHSVTRQ----PFVYLFDDFKKIYLDKRFLGLSLGLPLVGMPLML 234
+ L++ GL MP + TR+ L D+ + +KRFLG +L +PL+
Sbjct 181 SLLAFLGLYKAMP---ETATRRGETLSLSALGHDYALVLKNKRFLGGALACGFASLPLLA 237
Query 235 WIALSPVMLVDELKFSSVQYGLAQFPIFMGLILGNIVLIKIIDRFPLGKTILMGLPIMLV 294
WIA SPV+++ SS YG+ Q PIF LILGN L ++ R P+ + I +G M+
Sbjct 238 WIAQSPVIIISGEGLSSYDYGMLQVPIFGMLILGNFTLARLSGRRPVRRLIQLGAWPMVG 297
Query 295 GTLVLLVGAIWQDYLAVCLLVGMTLISFGEGISFSVIYRFALMSSPVAKGTVAAAVSMLL 354
G + V ++ + + + G++L +FG G++ + +YR L SS ++KGTV+AA+ M+
Sbjct 298 GLAIAAVSTLYSAHAYLWMTAGLSLYAFGIGLANAGLYRLTLFSSTMSKGTVSAAMGMIS 357
Query 355 MFSFFIMIELVRELYVHFHVLAFSLSCVVLITLWFLLPRLMLKQE 399
MF + + IE+ + ++ AF+L ++ LW L LML+ +
Sbjct 358 MFIYTLGIEVGKHAWLLGGNGAFNLFNLISGLLWLALVALMLRDK 402
>A9R4E0 Multidrug transporter MdfA [Yersinia pestis bv. Antiqua
(strain Angola)]
Length=409
Score = 314 bits (805), Expect = 2e-107
Identities = 167/394 (42%), Positives = 246/394 (62%), Gaps = 1/394 (0%)
Query 7 TTLNRTTLMFPLALVLFEFAVYIGNDLIQPAMLAITQDFAVSATWAPSSMSFYLLGGACV 66
T L R L+FPL LVLFEFA YI ND+IQP MLA+ +F S W P+SM+ YL GG +
Sbjct 9 TRLGRRALLFPLCLVLFEFAAYIANDMIQPGMLAVVAEFNASVEWVPTSMTAYLAGGMFL 68
Query 67 AWLLGPLSDRLGRKRVLLFGVLFFALCCLLILLTHNMAQFLALRFLQGIGLSVITAVGYA 126
WLLGPLSDR GR+ V+L GV FF + CL ILL +++ QF+A+RFLQGIGL I AVGYA
Sbjct 69 QWLLGPLSDRRGRRPVMLAGVAFFVVTCLAILLVNSIEQFIAMRFLQGIGLCFIGAVGYA 128
Query 127 AIQETFEERDAIKVMALMANISLLAPLLGPVLGAFLIDYVSWHWGFVAIATLAGLSWFGL 186
IQE+FEE IK+ ALMAN++L+APLLGP+ GA LI W FV A L +S+ GL
Sbjct 129 TIQESFEEAVCIKITALMANVALIAPLLGPLAGAALIHVAPWQTMFVLFAVLGAISFAGL 188
Query 187 KAKMP-SQQHSVTRQPFVYLFDDFKKIYLDKRFLGLSLGLPLVGMPLMLWIALSPVMLVD 245
MP + + ++ D+K++ ++RFL SL L +PL+ WIA SPV+L+
Sbjct 189 WRAMPETASLKGEKLSVANMWRDYKQVLANRRFLCGSLALGFASLPLLAWIAQSPVILIS 248
Query 246 ELKFSSVQYGLAQFPIFMGLILGNIVLIKIIDRFPLGKTILMGLPIMLVGTLVLLVGAIW 305
+ S+ +YG+ Q PIF LI+GN+ L ++ + + + I G M+VG ++ ++
Sbjct 249 GEQLSTFEYGILQVPIFGALIIGNLTLARLSGKTSIPQLIRYGAGPMIVGLMIAAGSTLY 308
Query 306 QDYLAVCLLVGMTLISFGEGISFSVIYRFALMSSPVAKGTVAAAVSMLLMFSFFIMIELV 365
+ + + G++L +FG G++ + + R L +S ++KGTV+AA+ M+ M F + IEL
Sbjct 309 SSHAYLWMTAGLSLYAFGIGLANAGLVRLTLFASDISKGTVSAAMGMISMMIFTLGIELA 368
Query 366 RELYVHFHVLAFSLSCVVLITLWFLLPRLMLKQE 399
+ Y+ F+L ++ LW L + ++++
Sbjct 369 KVAYLWGDSRGFNLFNLMSGLLWLGLVMVFIRRQ 402
>D5B5U5 Multidrug transporter MdfA [Yersinia pestis (strain Z176003)]
Length=409
Score = 314 bits (805), Expect = 2e-107
Identities = 167/394 (42%), Positives = 246/394 (62%), Gaps = 1/394 (0%)
Query 7 TTLNRTTLMFPLALVLFEFAVYIGNDLIQPAMLAITQDFAVSATWAPSSMSFYLLGGACV 66
T L R L+FPL LVLFEFA YI ND+IQP MLA+ +F S W P+SM+ YL GG +
Sbjct 9 TRLGRRALLFPLCLVLFEFAAYIANDMIQPGMLAVVAEFNASVEWVPTSMTAYLAGGMFL 68
Query 67 AWLLGPLSDRLGRKRVLLFGVLFFALCCLLILLTHNMAQFLALRFLQGIGLSVITAVGYA 126
WLLGPLSDR GR+ V+L GV FF + CL ILL +++ QF+A+RFLQGIGL I AVGYA
Sbjct 69 QWLLGPLSDRRGRRPVMLAGVAFFVVTCLAILLVNSIEQFIAMRFLQGIGLCFIGAVGYA 128
Query 127 AIQETFEERDAIKVMALMANISLLAPLLGPVLGAFLIDYVSWHWGFVAIATLAGLSWFGL 186
IQE+FEE IK+ ALMAN++L+APLLGP+ GA LI W FV A L +S+ GL
Sbjct 129 TIQESFEEAVCIKITALMANVALIAPLLGPLAGAALIHVAPWQTMFVLFAVLGAISFAGL 188
Query 187 KAKMP-SQQHSVTRQPFVYLFDDFKKIYLDKRFLGLSLGLPLVGMPLMLWIALSPVMLVD 245
MP + + ++ D+K++ ++RFL SL L +PL+ WIA SPV+L+
Sbjct 189 WRAMPETASLKGEKLSVANMWRDYKQVLANRRFLCGSLALGFASLPLLAWIAQSPVILIS 248
Query 246 ELKFSSVQYGLAQFPIFMGLILGNIVLIKIIDRFPLGKTILMGLPIMLVGTLVLLVGAIW 305
+ S+ +YG+ Q PIF LI+GN+ L ++ + + + I G M+VG ++ ++
Sbjct 249 GEQLSTFEYGILQVPIFGALIIGNLTLARLSGKTSIPQLIRYGAGPMIVGLMIAAGSTLY 308
Query 306 QDYLAVCLLVGMTLISFGEGISFSVIYRFALMSSPVAKGTVAAAVSMLLMFSFFIMIELV 365
+ + + G++L +FG G++ + + R L +S ++KGTV+AA+ M+ M F + IEL
Sbjct 309 SSHAYLWMTAGLSLYAFGIGLANAGLVRLTLFASDISKGTVSAAMGMISMMIFTLGIELA 368
Query 366 RELYVHFHVLAFSLSCVVLITLWFLLPRLMLKQE 399
+ Y+ F+L ++ LW L + ++++
Sbjct 369 KVAYLWGDSRGFNLFNLMSGLLWLGLVMVFIRRQ 402
>D0JKF6 Multidrug transporter MdfA [Yersinia pestis (strain D106004)]
Length=409
Score = 314 bits (805), Expect = 2e-107
Identities = 167/394 (42%), Positives = 246/394 (62%), Gaps = 1/394 (0%)
Query 7 TTLNRTTLMFPLALVLFEFAVYIGNDLIQPAMLAITQDFAVSATWAPSSMSFYLLGGACV 66
T L R L+FPL LVLFEFA YI ND+IQP MLA+ +F S W P+SM+ YL GG +
Sbjct 9 TRLGRRALLFPLCLVLFEFAAYIANDMIQPGMLAVVAEFNASVEWVPTSMTAYLAGGMFL 68
Query 67 AWLLGPLSDRLGRKRVLLFGVLFFALCCLLILLTHNMAQFLALRFLQGIGLSVITAVGYA 126
WLLGPLSDR GR+ V+L GV FF + CL ILL +++ QF+A+RFLQGIGL I AVGYA
Sbjct 69 QWLLGPLSDRRGRRPVMLAGVAFFVVTCLAILLVNSIEQFIAMRFLQGIGLCFIGAVGYA 128
Query 127 AIQETFEERDAIKVMALMANISLLAPLLGPVLGAFLIDYVSWHWGFVAIATLAGLSWFGL 186
IQE+FEE IK+ ALMAN++L+APLLGP+ GA LI W FV A L +S+ GL
Sbjct 129 TIQESFEEAVCIKITALMANVALIAPLLGPLAGAALIHVAPWQTMFVLFAVLGAISFAGL 188
Query 187 KAKMP-SQQHSVTRQPFVYLFDDFKKIYLDKRFLGLSLGLPLVGMPLMLWIALSPVMLVD 245
MP + + ++ D+K++ ++RFL SL L +PL+ WIA SPV+L+
Sbjct 189 WRAMPETASLKGEKLSVANMWRDYKQVLANRRFLCGSLALGFASLPLLAWIAQSPVILIS 248
Query 246 ELKFSSVQYGLAQFPIFMGLILGNIVLIKIIDRFPLGKTILMGLPIMLVGTLVLLVGAIW 305
+ S+ +YG+ Q PIF LI+GN+ L ++ + + + I G M+VG ++ ++
Sbjct 249 GEQLSTFEYGILQVPIFGALIIGNLTLARLSGKTSIPQLIRYGAGPMIVGLMIAAGSTLY 308
Query 306 QDYLAVCLLVGMTLISFGEGISFSVIYRFALMSSPVAKGTVAAAVSMLLMFSFFIMIELV 365
+ + + G++L +FG G++ + + R L +S ++KGTV+AA+ M+ M F + IEL
Sbjct 309 SSHAYLWMTAGLSLYAFGIGLANAGLVRLTLFASDISKGTVSAAMGMISMMIFTLGIELA 368
Query 366 RELYVHFHVLAFSLSCVVLITLWFLLPRLMLKQE 399
+ Y+ F+L ++ LW L + ++++
Sbjct 369 KVAYLWGDSRGFNLFNLMSGLLWLGLVMVFIRRQ 402
>D0JUX5 Multidrug transporter MdfA [Yersinia pestis (strain D182038)]
Length=409
Score = 314 bits (805), Expect = 2e-107
Identities = 167/394 (42%), Positives = 246/394 (62%), Gaps = 1/394 (0%)
Query 7 TTLNRTTLMFPLALVLFEFAVYIGNDLIQPAMLAITQDFAVSATWAPSSMSFYLLGGACV 66
T L R L+FPL LVLFEFA YI ND+IQP MLA+ +F S W P+SM+ YL GG +
Sbjct 9 TRLGRRALLFPLCLVLFEFAAYIANDMIQPGMLAVVAEFNASVEWVPTSMTAYLAGGMFL 68
Query 67 AWLLGPLSDRLGRKRVLLFGVLFFALCCLLILLTHNMAQFLALRFLQGIGLSVITAVGYA 126
WLLGPLSDR GR+ V+L GV FF + CL ILL +++ QF+A+RFLQGIGL I AVGYA
Sbjct 69 QWLLGPLSDRRGRRPVMLAGVAFFVVTCLAILLVNSIEQFIAMRFLQGIGLCFIGAVGYA 128
Query 127 AIQETFEERDAIKVMALMANISLLAPLLGPVLGAFLIDYVSWHWGFVAIATLAGLSWFGL 186
IQE+FEE IK+ ALMAN++L+APLLGP+ GA LI W FV A L +S+ GL
Sbjct 129 TIQESFEEAVCIKITALMANVALIAPLLGPLAGAALIHVAPWQTMFVLFAVLGAISFAGL 188
Query 187 KAKMP-SQQHSVTRQPFVYLFDDFKKIYLDKRFLGLSLGLPLVGMPLMLWIALSPVMLVD 245
MP + + ++ D+K++ ++RFL SL L +PL+ WIA SPV+L+
Sbjct 189 WRAMPETASLKGEKLSVANMWRDYKQVLANRRFLCGSLALGFASLPLLAWIAQSPVILIS 248
Query 246 ELKFSSVQYGLAQFPIFMGLILGNIVLIKIIDRFPLGKTILMGLPIMLVGTLVLLVGAIW 305
+ S+ +YG+ Q PIF LI+GN+ L ++ + + + I G M+VG ++ ++
Sbjct 249 GEQLSTFEYGILQVPIFGALIIGNLTLARLSGKTSIPQLIRYGAGPMIVGLMIAAGSTLY 308
Query 306 QDYLAVCLLVGMTLISFGEGISFSVIYRFALMSSPVAKGTVAAAVSMLLMFSFFIMIELV 365
+ + + G++L +FG G++ + + R L +S ++KGTV+AA+ M+ M F + IEL
Sbjct 309 SSHAYLWMTAGLSLYAFGIGLANAGLVRLTLFASDISKGTVSAAMGMISMMIFTLGIELA 368
Query 366 RELYVHFHVLAFSLSCVVLITLWFLLPRLMLKQE 399
+ Y+ F+L ++ LW L + ++++
Sbjct 369 KVAYLWGDSRGFNLFNLMSGLLWLGLVMVFIRRQ 402
>P0AEY9 Multidrug transporter MdfA [Escherichia coli O6:H1 (strain
CFT073 / ATCC 700928 / UPEC)]
Length=410
Score = 311 bits (797), Expect = 3e-106
Identities = 167/392 (43%), Positives = 246/392 (63%), Gaps = 1/392 (0%)
Query 9 LNRTTLMFPLALVLFEFAVYIGNDLIQPAMLAITQDFAVSATWAPSSMSFYLLGGACVAW 68
L R L+FPL LVL+EF+ YIGND+IQP MLA+ + + W P+SM+ YL GG + W
Sbjct 11 LGRQALLFPLCLVLYEFSTYIGNDMIQPGMLAVVEQYQAGIDWVPTSMTAYLAGGMFLQW 70
Query 69 LLGPLSDRLGRKRVLLFGVLFFALCCLLILLTHNMAQFLALRFLQGIGLSVITAVGYAAI 128
LLGPLSDR+GR+ V+L GV++F + CL ILL N+ QF LRFLQGI L I AVGYAAI
Sbjct 71 LLGPLSDRIGRRPVMLAGVVWFIVTCLAILLAQNIEQFTLLRFLQGISLCFIGAVGYAAI 130
Query 129 QETFEERDAIKVMALMANISLLAPLLGPVLGAFLIDYVSWHWGFVAIATLAGLSWFGLKA 188
QE+FEE IK+ ALMAN++L+APLLGP++GA I + W FV A LA +S+FGL+
Sbjct 131 QESFEEAVCIKITALMANVALIAPLLGPLVGAAWIHVLPWEGMFVLFAALAAISFFGLQR 190
Query 189 KMPSQQHSV-TRQPFVYLFDDFKKIYLDKRFLGLSLGLPLVGMPLMLWIALSPVMLVDEL 247
MP + + L D+K + + RF+ +L L V +PL+ WIA SP++++
Sbjct 191 AMPETATRIGEKLSLKELGRDYKLVLKNGRFVAGALALGFVSLPLLAWIAQSPIIIITGE 250
Query 248 KFSSVQYGLAQFPIFMGLILGNIVLIKIIDRFPLGKTILMGLPIMLVGTLVLLVGAIWQD 307
+ SS +YGL Q PIF LI GN++L ++ R + I+MG +++G LV +
Sbjct 251 QLSSYEYGLLQVPIFGALIAGNLLLARLTSRRTVRSLIIMGGWPIMIGLLVAAAATVISS 310
Query 308 YLAVCLLVGMTLISFGEGISFSVIYRFALMSSPVAKGTVAAAVSMLLMFSFFIMIELVRE 367
+ + + G+++ +FG G++ + + R L +S ++KGTV+AA+ ML M F + IE+ +
Sbjct 311 HAYLWMTAGLSIYAFGIGLANAGLVRLTLFASDMSKGTVSAAMGMLQMLIFTVGIEISKH 370
Query 368 LYVHFHVLAFSLSCVVLITLWFLLPRLMLKQE 399
+++ F+L +V LW L + LK +
Sbjct 371 AWLNGGNGLFNLFNLVNGILWLSLMVIFLKDK 402
>P0AEZ0 Multidrug transporter MdfA [Escherichia coli O157:H7]
Length=410
Score = 311 bits (797), Expect = 3e-106
Identities = 167/392 (43%), Positives = 246/392 (63%), Gaps = 1/392 (0%)
Query 9 LNRTTLMFPLALVLFEFAVYIGNDLIQPAMLAITQDFAVSATWAPSSMSFYLLGGACVAW 68
L R L+FPL LVL+EF+ YIGND+IQP MLA+ + + W P+SM+ YL GG + W
Sbjct 11 LGRQALLFPLCLVLYEFSTYIGNDMIQPGMLAVVEQYQAGIDWVPTSMTAYLAGGMFLQW 70
Query 69 LLGPLSDRLGRKRVLLFGVLFFALCCLLILLTHNMAQFLALRFLQGIGLSVITAVGYAAI 128
LLGPLSDR+GR+ V+L GV++F + CL ILL N+ QF LRFLQGI L I AVGYAAI
Sbjct 71 LLGPLSDRIGRRPVMLAGVVWFIVTCLAILLAQNIEQFTLLRFLQGISLCFIGAVGYAAI 130
Query 129 QETFEERDAIKVMALMANISLLAPLLGPVLGAFLIDYVSWHWGFVAIATLAGLSWFGLKA 188
QE+FEE IK+ ALMAN++L+APLLGP++GA I + W FV A LA +S+FGL+
Sbjct 131 QESFEEAVCIKITALMANVALIAPLLGPLVGAAWIHVLPWEGMFVLFAALAAISFFGLQR 190
Query 189 KMPSQQHSV-TRQPFVYLFDDFKKIYLDKRFLGLSLGLPLVGMPLMLWIALSPVMLVDEL 247
MP + + L D+K + + RF+ +L L V +PL+ WIA SP++++
Sbjct 191 AMPETATRIGEKLSLKELGRDYKLVLKNGRFVAGALALGFVSLPLLAWIAQSPIIIITGE 250
Query 248 KFSSVQYGLAQFPIFMGLILGNIVLIKIIDRFPLGKTILMGLPIMLVGTLVLLVGAIWQD 307
+ SS +YGL Q PIF LI GN++L ++ R + I+MG +++G LV +
Sbjct 251 QLSSYEYGLLQVPIFGALIAGNLLLARLTSRRTVRSLIIMGGWPIMIGLLVAAAATVISS 310
Query 308 YLAVCLLVGMTLISFGEGISFSVIYRFALMSSPVAKGTVAAAVSMLLMFSFFIMIELVRE 367
+ + + G+++ +FG G++ + + R L +S ++KGTV+AA+ ML M F + IE+ +
Sbjct 311 HAYLWMTAGLSIYAFGIGLANAGLVRLTLFASDMSKGTVSAAMGMLQMLIFTVGIEISKH 370
Query 368 LYVHFHVLAFSLSCVVLITLWFLLPRLMLKQE 399
+++ F+L +V LW L + LK +
Sbjct 371 AWLNGGNGLFNLFNLVNGILWLSLMVIFLKDK 402
>P0AEY8 Multidrug transporter MdfA [Escherichia coli (strain K12)]
Length=410
Score = 311 bits (797), Expect = 3e-106
Identities = 167/392 (43%), Positives = 246/392 (63%), Gaps = 1/392 (0%)
Query 9 LNRTTLMFPLALVLFEFAVYIGNDLIQPAMLAITQDFAVSATWAPSSMSFYLLGGACVAW 68
L R L+FPL LVL+EF+ YIGND+IQP MLA+ + + W P+SM+ YL GG + W
Sbjct 11 LGRQALLFPLCLVLYEFSTYIGNDMIQPGMLAVVEQYQAGIDWVPTSMTAYLAGGMFLQW 70
Query 69 LLGPLSDRLGRKRVLLFGVLFFALCCLLILLTHNMAQFLALRFLQGIGLSVITAVGYAAI 128
LLGPLSDR+GR+ V+L GV++F + CL ILL N+ QF LRFLQGI L I AVGYAAI
Sbjct 71 LLGPLSDRIGRRPVMLAGVVWFIVTCLAILLAQNIEQFTLLRFLQGISLCFIGAVGYAAI 130
Query 129 QETFEERDAIKVMALMANISLLAPLLGPVLGAFLIDYVSWHWGFVAIATLAGLSWFGLKA 188
QE+FEE IK+ ALMAN++L+APLLGP++GA I + W FV A LA +S+FGL+
Sbjct 131 QESFEEAVCIKITALMANVALIAPLLGPLVGAAWIHVLPWEGMFVLFAALAAISFFGLQR 190
Query 189 KMPSQQHSV-TRQPFVYLFDDFKKIYLDKRFLGLSLGLPLVGMPLMLWIALSPVMLVDEL 247
MP + + L D+K + + RF+ +L L V +PL+ WIA SP++++
Sbjct 191 AMPETATRIGEKLSLKELGRDYKLVLKNGRFVAGALALGFVSLPLLAWIAQSPIIIITGE 250
Query 248 KFSSVQYGLAQFPIFMGLILGNIVLIKIIDRFPLGKTILMGLPIMLVGTLVLLVGAIWQD 307
+ SS +YGL Q PIF LI GN++L ++ R + I+MG +++G LV +
Sbjct 251 QLSSYEYGLLQVPIFGALIAGNLLLARLTSRRTVRSLIIMGGWPIMIGLLVAAAATVISS 310
Query 308 YLAVCLLVGMTLISFGEGISFSVIYRFALMSSPVAKGTVAAAVSMLLMFSFFIMIELVRE 367
+ + + G+++ +FG G++ + + R L +S ++KGTV+AA+ ML M F + IE+ +
Sbjct 311 HAYLWMTAGLSIYAFGIGLANAGLVRLTLFASDMSKGTVSAAMGMLQMLIFTVGIEISKH 370
Query 368 LYVHFHVLAFSLSCVVLITLWFLLPRLMLKQE 399
+++ F+L +V LW L + LK +
Sbjct 371 AWLNGGNGLFNLFNLVNGILWLSLMVIFLKDK 402
>C5BC70 Multidrug transporter MdfA [Edwardsiella ictaluri (strain
93-146)]
Length=410
Score = 310 bits (793), Expect = 1e-105
Identities = 174/409 (43%), Positives = 253/409 (62%), Gaps = 9/409 (2%)
Query 1 MQNVRTTT--LNRTTLMFPLALVLFEFAVYIGNDLIQPAMLAITQDFAVSATWAPSSMSF 58
MQN ++T L R L+FPL LVL+EFA YIGND+IQP ML++ Q F V +W P+SM+
Sbjct 1 MQNHLSSTRRLGRRALLFPLCLVLYEFATYIGNDMIQPGMLSVVQTFGVDESWVPTSMTA 60
Query 59 YLLGGACVAWLLGPLSDRLGRKRVLLFGVLFFALCCLLILLTHNMAQFLALRFLQGIGLS 118
YL GG + WLLGPLSDR+GR+ V+L G L+FA CL ILLT+++ QF +RFLQGI L
Sbjct 61 YLAGGMFLQWLLGPLSDRIGRRPVMLIGTLYFAATCLAILLTNSIEQFTLMRFLQGISLC 120
Query 119 VITAVGYAAIQETFEERDAIKVMALMANISLLAPLLGPVLGAFLIDYVSWHWGFVAIATL 178
I AVGYAAIQE+FEE IK+ ALMAN++L+APLLGP+ GA + W F+ A L
Sbjct 121 FIGAVGYAAIQESFEESVCIKITALMANVALIAPLLGPLAGAAWVHLFPWEGMFILFAAL 180
Query 179 AGLSWFGLKAKMPSQQHSVTRQ----PFVYLFDDFKKIYLDKRFLGLSLGLPLVGMPLML 234
+ L++ GL MP + TR+ L D+ + ++RFL SL +PL+
Sbjct 181 SLLAFLGLYKAMP---ETATRRGEKLSLSALGRDYTLVLKNRRFLCGSLACGFASLPLLA 237
Query 235 WIALSPVMLVDELKFSSVQYGLAQFPIFMGLILGNIVLIKIIDRFPLGKTILMGLPIMLV 294
WIA SPV+++ SS YG+ Q PIF LILGN+ L ++ R P+ + I +G M+
Sbjct 238 WIAQSPVIIISGEGLSSYDYGMLQVPIFGMLILGNLTLARLSGRRPVRRLIQLGAWPMVG 297
Query 295 GTLVLLVGAIWQDYLAVCLLVGMTLISFGEGISFSVIYRFALMSSPVAKGTVAAAVSMLL 354
G + ++ + + + G++L +FG G++ + +YR L SS ++KGTV+AA+ M+
Sbjct 298 GLAIAAASTLYSAHAYLWMTAGLSLYAFGIGLANAGLYRLTLFSSTMSKGTVSAAMGMIS 357
Query 355 MFSFFIMIELVRELYVHFHVLAFSLSCVVLITLWFLLPRLMLKQEMAIR 403
MF + + IE+ + ++ AF+L ++ LW L ML+ ++ R
Sbjct 358 MFIYTLGIEVGKYAWLLGGNGAFNLFNLISGLLWLALIARMLRDQLVGR 406
>Q323U7 Multidrug transporter MdfA [Shigella boydii serotype 4
(strain Sb227)]
Length=410
Score = 308 bits (790), Expect = 3e-105
Identities = 166/392 (42%), Positives = 245/392 (63%), Gaps = 1/392 (0%)
Query 9 LNRTTLMFPLALVLFEFAVYIGNDLIQPAMLAITQDFAVSATWAPSSMSFYLLGGACVAW 68
L R L+FPL LVL+EF+ YIG D+IQP MLA+ + + W P+SM+ YL GG + W
Sbjct 11 LGRQALLFPLCLVLYEFSTYIGADMIQPGMLAVVEQYQAGIDWVPTSMTAYLAGGMFLQW 70
Query 69 LLGPLSDRLGRKRVLLFGVLFFALCCLLILLTHNMAQFLALRFLQGIGLSVITAVGYAAI 128
LLGPLSDR+GR+ V+L GV++F + CL ILL N+ QF LRFLQGI L I AVGYAAI
Sbjct 71 LLGPLSDRIGRRPVMLAGVVWFIITCLAILLAQNIEQFTLLRFLQGISLCFIGAVGYAAI 130
Query 129 QETFEERDAIKVMALMANISLLAPLLGPVLGAFLIDYVSWHWGFVAIATLAGLSWFGLKA 188
QE+FEE IK+ ALMAN++L+APLLGP++GA I + W FV A LA +S+FGL+
Sbjct 131 QESFEEAVCIKITALMANVALIAPLLGPLVGAAWIHVLPWEGMFVLFAALAAISFFGLQR 190
Query 189 KMPSQQHSV-TRQPFVYLFDDFKKIYLDKRFLGLSLGLPLVGMPLMLWIALSPVMLVDEL 247
MP + + L D+K + + RF+ +L L V +PL+ WIA SP++++
Sbjct 191 AMPETATRIGEKLSLKELGRDYKLVLKNGRFVAGALALGFVSLPLLAWIAQSPIIIITGE 250
Query 248 KFSSVQYGLAQFPIFMGLILGNIVLIKIIDRFPLGKTILMGLPIMLVGTLVLLVGAIWQD 307
+ SS +YGL Q PIF LI GN++L ++ R + I+MG +++G LV +
Sbjct 251 QLSSYEYGLLQVPIFGALIAGNLLLARLTSRRTVRSLIIMGGWPIMIGLLVAAAATVISS 310
Query 308 YLAVCLLVGMTLISFGEGISFSVIYRFALMSSPVAKGTVAAAVSMLLMFSFFIMIELVRE 367
+ + + G+++ +FG G++ + + R L +S ++KGTV+AA+ ML M F + IE+ +
Sbjct 311 HAYLWMTAGLSIYAFGIGLANAGLVRLTLFASDMSKGTVSAAMGMLQMLIFTVGIEISKH 370
Query 368 LYVHFHVLAFSLSCVVLITLWFLLPRLMLKQE 399
+++ F+L +V LW L + LK +
Sbjct 371 AWLNGGNGQFNLFNLVNGILWLSLMVIFLKDK 402
>Q7CP73 Multidrug resistance protein MdtM [Salmonella typhimurium
(strain LT2 / SGSC1412 / ATCC 700720)]
Length=413
Score = 277 bits (709), Expect = 5e-93
Identities = 149/389 (38%), Positives = 238/389 (61%), Gaps = 6/389 (2%)
Query 12 TTLMFPLALVLFEFAVYIGNDLIQPAMLAITQDFAVSATWAPSSMSFYLLGGACVAWLLG 71
TTL FP+AL+L++FA Y+ DLIQP ++ + +DF + AP+S+S YL GG + WLLG
Sbjct 13 TTLFFPMALILYDFAAYLTTDLIQPGIINVVRDFNADVSLAPASVSLYLAGGMALQWLLG 72
Query 72 PLSDRLGRKRVLLFGVLFFALCCLLILLTHNMAQFLALRFLQGIGLSVITAVGYAAIQET 131
PLSDR+GR+ VL+ G L F L C LLT +M QFL RF+QG + I VGY +QE
Sbjct 73 PLSDRIGRRPVLIAGALIFTLACAATLLTTSMTQFLVARFVQGTSICFIATVGYVTVQEA 132
Query 132 FEERDAIKVMALMANISLLAPLLGPVLGAFLIDYVSWHWGFVAIATLAGLSWFGLKAKMP 191
F + AIK+MA++ +I L+AP++GP+ GA L+ +V W F IA + L+ GL MP
Sbjct 133 FGQTKAIKLMAIITSIVLVAPVIGPLSGAALMHFVHWKVLFGIIAVMGLLALCGLLLAMP 192
Query 192 -SQQHSVTRQPFVYLFDDFKKIYLDKRFLGLSLGLPLVGMPLMLWIALSPVMLVDELKFS 250
+ Q V + DF+ ++ + FL + L L +P+M W+A+SPV+L+D S
Sbjct 193 ETVQRGAVPFSAVSVLRDFRNVFRNPIFLTGAATLSLSYIPMMSWVAVSPVILIDAGGMS 252
Query 251 SVQYGLAQFPIFMGLILGNIVLIKIIDRFPLGKTILMGLPIMLVGTLVLLVGAIWQDYLA 310
+ Q+ AQ P+F +I+ N+++++++ + I +PI L G LL+G + ++
Sbjct 253 TSQFAWAQVPVFGAVIVANMIVVRLVKDPTRPRFIWRAVPIQLSGLATLLLGNLLLPHVW 312
Query 311 VCLLVGMTLISFGEGISFSVIYRFALMSSPVAKGTVAAAVSMLLMFSFFIMIELVRELYV 370
+ ++G +L +FG G+ F ++RF L S+ + KGTV+A+++M+++ + +E+ R L+
Sbjct 313 LWSVLGTSLYAFGIGMIFPTLFRFTLFSNNLPKGTVSASLNMVILTVMAVSVEVGRWLWF 372
Query 371 H-----FHVLAFSLSCVVLITLWFLLPRL 394
H FH+LA +V+ TL LL R+
Sbjct 373 HGGRLPFHLLAAVAGVIVVFTLATLLQRV 401
>Q8XFG0 Multidrug resistance protein MdtM [Salmonella typhi]
Length=413
Score = 277 bits (709), Expect = 5e-93
Identities = 149/389 (38%), Positives = 238/389 (61%), Gaps = 6/389 (2%)
Query 12 TTLMFPLALVLFEFAVYIGNDLIQPAMLAITQDFAVSATWAPSSMSFYLLGGACVAWLLG 71
TTL FP+AL+L++FA Y+ DLIQP ++ + +DF + AP+S+S YL GG + WLLG
Sbjct 13 TTLFFPMALILYDFAAYLTTDLIQPGIINVVRDFNADVSLAPASVSLYLAGGMALQWLLG 72
Query 72 PLSDRLGRKRVLLFGVLFFALCCLLILLTHNMAQFLALRFLQGIGLSVITAVGYAAIQET 131
PLSDR+GR+ VL+ G L F L C LLT +M QFL RF+QG + I VGY +QE
Sbjct 73 PLSDRIGRRPVLIAGALIFTLACAATLLTTSMTQFLVARFVQGTSICFIATVGYVTVQEA 132
Query 132 FEERDAIKVMALMANISLLAPLLGPVLGAFLIDYVSWHWGFVAIATLAGLSWFGLKAKMP 191
F + AIK+MA++ +I L+AP++GP+ GA L+ +V W F IA + L+ GL MP
Sbjct 133 FGQTKAIKLMAIITSIVLVAPVIGPLSGAALMHFVHWKVLFGIIAVMGLLALCGLLLAMP 192
Query 192 -SQQHSVTRQPFVYLFDDFKKIYLDKRFLGLSLGLPLVGMPLMLWIALSPVMLVDELKFS 250
+ Q V + DF+ ++ + FL + L L +P+M W+A+SPV+L+D S
Sbjct 193 ETVQRGAVPFSAVSVLRDFRNVFRNPIFLTGAATLSLSYIPMMSWVAVSPVILIDAGGMS 252
Query 251 SVQYGLAQFPIFMGLILGNIVLIKIIDRFPLGKTILMGLPIMLVGTLVLLVGAIWQDYLA 310
+ Q+ AQ P+F +I+ N+++++++ + I +PI L G LL+G + ++
Sbjct 253 TSQFAWAQVPVFGAVIVANMIVVRLVKDPTRPRFIWRAVPIQLSGLATLLLGNLLLPHVW 312
Query 311 VCLLVGMTLISFGEGISFSVIYRFALMSSPVAKGTVAAAVSMLLMFSFFIMIELVRELYV 370
+ ++G +L +FG G+ F ++RF L S+ + KGTV+A+++M+++ + +E+ R L+
Sbjct 313 LWSVLGTSLYAFGIGMIFPTLFRFTLFSNNLPKGTVSASLNMVILTVMAVSVEVGRWLWF 372
Query 371 H-----FHVLAFSLSCVVLITLWFLLPRL 394
H FH+LA +V+ TL LL R+
Sbjct 373 HGGRLPFHLLAAVAGVIVVFTLATLLQRV 401
>P39386 Multidrug resistance protein MdtM [Escherichia coli (strain
K12)]
Length=410
Score = 267 bits (683), Expect = 4e-89
Identities = 142/403 (35%), Positives = 239/403 (59%), Gaps = 12/403 (3%)
Query 5 RTTTLNRTTLMFPLALVLFEFAVYIGNDLIQPAMLAITQDFAVSATWAPSSMSFYLLGGA 64
R T + TL FP+AL+L++FA Y+ DLIQP ++ + +DF + AP+++S YL GG
Sbjct 3 RFFTRHAATLFFPMALILYDFAAYLSTDLIQPGIINVVRDFNADVSLAPAAVSLYLAGGM 62
Query 65 CVAWLLGPLSDRLGRKRVLLFGVLFFALCCLLILLTHNMAQFLALRFLQGIGLSVITAVG 124
+ WLLGPLSDR+GR+ VL+ G L F L C + T +M QFL R +QG + I VG
Sbjct 63 ALQWLLGPLSDRIGRRPVLITGALIFTLACAATMFTTSMTQFLIARAIQGTSICFIATVG 122
Query 125 YAAIQETFEERDAIKVMALMANISLLAPLLGPVLGAFLIDYVSWHWGFVAIATLAGLSWF 184
Y +QE F + IK+MA++ +I L+AP++GP+ GA L+ ++ W F IA + +S+
Sbjct 123 YVTVQEAFGQTKGIKLMAIITSIVLIAPIIGPLSGAALMHFMHWKVLFAIIAVMGFISFV 182
Query 185 GLKAKMPSQQHSVTRQPFVY----LFDDFKKIYLDKRFLGLSLGLPLVGMPLMLWIALSP 240
GL MP +V R + + DF+ ++ ++ FL + + L +P+M W+A+SP
Sbjct 183 GLLLAMP---ETVKRGAVPFSAKSVLRDFRNVFCNRLFLFGAATISLSYIPMMSWVAVSP 239
Query 241 VMLVDELKFSSVQYGLAQFPIFMGLILGNIVLIKIIDRFPLGKTILMGLPIMLVGTLVLL 300
V+L+D ++ Q+ Q P+F +I+ N ++ + + + I +PI LVG +L+
Sbjct 240 VILIDAGSLTTSQFAWTQVPVFGAVIVANAIVARFVKDPTEPRFIWRAVPIQLVGLSLLI 299
Query 301 VGAIWQDYLAVCLLVGMTLISFGEGISFSVIYRFALMSSPVAKGTVAAAVSMLLMFSFFI 360
VG + ++ + ++G +L +FG G+ F ++RF L S+ + KGTV+A+++M+++ +
Sbjct 300 VGNLLSPHVWLWSVLGTSLYAFGIGLIFPTLFRFTLFSNKLPKGTVSASLNMVILMVMSV 359
Query 361 MIELVRELYVH-----FHVLAFSLSCVVLITLWFLLPRLMLKQ 398
+E+ R L+ + FH+LA +V+ TL LL R+ Q
Sbjct 360 SVEIGRWLWFNGGRLPFHLLAVVAGVIVVFTLAGLLNRVRQHQ 402
>Q8XB84 Multidrug resistance protein MdtM [Escherichia coli O157:H7]
Length=410
Score = 267 bits (682), Expect = 5e-89
Identities = 141/395 (36%), Positives = 236/395 (60%), Gaps = 12/395 (3%)
Query 13 TLMFPLALVLFEFAVYIGNDLIQPAMLAITQDFAVSATWAPSSMSFYLLGGACVAWLLGP 72
TL FP+AL+L++FA Y+ DLIQP ++ + +DF + AP+++S YL GG + WLLGP
Sbjct 11 TLFFPMALILYDFAAYLSTDLIQPGIINVVRDFNADVSLAPAAVSLYLAGGMALQWLLGP 70
Query 73 LSDRLGRKRVLLFGVLFFALCCLLILLTHNMAQFLALRFLQGIGLSVITAVGYAAIQETF 132
LSDR+GRK VL+ G L F L C + T +M QFL R +QG + I VGY +QE F
Sbjct 71 LSDRIGRKPVLITGALIFTLACAATMFTTSMTQFLIARAIQGTSICFIATVGYVTVQEAF 130
Query 133 EERDAIKVMALMANISLLAPLLGPVLGAFLIDYVSWHWGFVAIATLAGLSWFGLKAKMPS 192
+ IK+MA++ +I L+AP++GP+ GA L+ +V W F IA + +S+ GL MP
Sbjct 131 GQTKGIKLMAIITSIVLIAPIIGPLSGAALMHFVHWKVLFAIIAVMGFISFVGLLLAMP- 189
Query 193 QQHSVTRQPFVY----LFDDFKKIYLDKRFLGLSLGLPLVGMPLMLWIALSPVMLVDELK 248
+V R + + DF+ ++ ++ FL + + L +P+M W+A+SPV+L+D
Sbjct 190 --ETVKRGAVPFSAKSVLRDFRNVFCNRLFLFGAATISLSYIPMMSWVAVSPVILIDAGG 247
Query 249 FSSVQYGLAQFPIFMGLILGNIVLIKIIDRFPLGKTILMGLPIMLVGTLVLLVGAIWQDY 308
++ Q+ Q P+F +I+ N ++ + + + I +PI LVG +L++G + +
Sbjct 248 LTTSQFAWTQVPVFGAVIVANAIVARFVKDPTEPRFIWRAVPIQLVGLALLIIGNLLSPH 307
Query 309 LAVCLLVGMTLISFGEGISFSVIYRFALMSSPVAKGTVAAAVSMLLMFSFFIMIELVREL 368
+ + ++G +L +FG G+ F ++RF L S+ + KGTV+A+++M+++ + +E+ R L
Sbjct 308 VWLWSVLGTSLYAFGIGLIFPTLFRFTLFSNNLPKGTVSASLNMVILMVMSVSVEIGRWL 367
Query 369 YVH-----FHVLAFSLSCVVLITLWFLLPRLMLKQ 398
+ + FH+LA +V+ TL LL R+ Q
Sbjct 368 WFNGGRLPFHLLAVVAGVIVVFTLAGLLNRVRQHQ 402
>P37597 Inner membrane transport protein YdhC [Escherichia coli
(strain K12)]
Length=403
Score = 118 bits (295), Expect = 1e-32
Identities = 99/375 (26%), Positives = 168/375 (45%), Gaps = 19/375 (5%)
Query 28 YIGNDLIQPAMLAITQDFAVSATWAPSSMSFYLLGGACVAWLLGPLSDRLGRKRVLLFGV 87
++ D+ PA AI D A+ +S+S +L G A L GPLSDR GRK VLL G+
Sbjct 19 FLATDMYLPAFAAIQADLQTPASAVSASLSLFLAGFAAAQLLWGPLSDRYGRKPVLLIGL 78
Query 88 LFFALCCLLILLTHNMAQFLALRFLQGIGLSVITAVGYAAIQETFEERDAIKVMALMANI 147
FAL L +L N A L LRF+Q +G+ + A + + + + ++ A + +
Sbjct 79 TIFALGSLGMLWVENAATLLVLRFVQAVGVCAAAVIWQALVTDYYPSQKVNRIFAAIMPL 138
Query 148 SLLAPLLGPVLGAFLIDYVSWHWGFV---AIATLAGLSWFGLKAKMPSQQHSVTRQPFVY 204
L+P L P+LG++L+ + SW F AI + L F LK ++ +S F
Sbjct 139 VGLSPALAPLLGSWLLVHFSWQAIFATLFAITVVLILPIFWLKPTTKARNNSQDGLTFTD 198
Query 205 LFDDFKKIYLDKRFLGLSLGLPLVGMPLMLWIALSPVMLVDELKFSSVQYGLAQFPIFMG 264
L K + G L W+ SP +L E+ +S GL+ P +
Sbjct 199 LL-------RSKTYRGNVLIYAACSASFFAWLTGSPFIL-SEMGYSPAVIGLSYVPQTIA 250
Query 265 LILGNIVLIKIIDRFPLGKTILMGLPIMLVGTLVLLVGAIWQDYLA-VCLLVGMTLISFG 323
++G + ++ GK +L L ++ +++ A + +++ V +L+ +++
Sbjct 251 FLIGGYGCRAALQKWQ-GKQLLPWLLVLFAVSVIATWAAGFISHVSLVEILIPFCVMAIA 309
Query 324 EGISFSVIYRFALMSSPVAKGTVAAAVSMLLMFSFFIMIELVRELYVHFH-----VLAFS 378
G + ++ AL P A G AAA+ L + LV + +
Sbjct 310 NGAIYPIVVAQALRPFPHATGR-AAALQNTLQLGLCFLASLVVSWLISISTPLLTTTSVM 368
Query 379 LSCVVLITLWFLLPR 393
LS VVL+ L +++ R
Sbjct 369 LSTVVLVALGYMMQR 383
>P28246 Bicyclomycin resistance protein [Escherichia coli (strain
K12)]
Length=396
Score = 101 bits (252), Expect = 8e-27
Identities = 77/325 (24%), Positives = 152/325 (47%), Gaps = 29/325 (9%)
Query 7 TTLNRTTLMFPLALVLFEFAVYIGNDLIQPAMLAITQDFAVSATWAPSSMSFYLLGGACV 66
TT ++ L L + + D+ PA+ I+ F V A ++S Y+LG A
Sbjct 2 TTRQHSSFAIVFILGLLAMLMPLSIDMYLPALPVISAQFGVPAGSTQMTLSTYILGFALG 61
Query 67 AWLLGPLSDRLGRKRVLLFGVLFFALCCLLILLTHNMAQFLALRFLQGIGLSVITAVGYA 126
+ GP++D GRK V+L G L FA + L + + Q + +RF G+ + + V A
Sbjct 62 QLIYGPMADSFGRKPVVLGGTLVFAAAAVACALANTIDQLIVMRFFHGLAAAAASVVINA 121
Query 127 AIQETFEERDAIKVMALMANISLLAPLLGPVLGAFLIDYVSWHWGFVAIATLAGLS---- 182
+++ + + + ++M+ + ++ +APL+ P++G +++ ++SWH+ F +A A L+
Sbjct 122 LMRDIYPKEEFSRMMSFVMLVTTIAPLMAPIVGGWVLVWLSWHYIFWILALAAILASAMI 181
Query 183 WFGLKAKMPSQQHSVTRQPFVY--LFDDFKKIYLDKRFLG--LSLGLPLVGMPLMLWIAL 238
+F +K +P ++ RQPF +F ++ KR L L+ G GM +++
Sbjct 182 FFLIKETLPPER----RQPFHIRTTIGNFAALFRHKRVLSYMLASGFSFAGM--FSFLSA 235
Query 239 SPVMLVDELKFSSVQYGLAQFPIFMGLILGNIVLIKIIDRFPLGKTILMGLPIMLVGTLV 298
P + ++ + +G + L NIV + ++ TI + +G L
Sbjct 236 GPFVYIEINHVAPENFG-----YYFAL---NIVFLFVM-------TIFNSRFVRRIGALN 280
Query 299 LLVGAIWQDYLAVCLLVGMTLISFG 323
+ +W ++ +V L+ G
Sbjct 281 MFRSGLWIQFIMAAWMVISALLGLG 305
>P31462 Multidrug resistance protein MdtL [Escherichia coli (strain
K12)]
Length=391
Score = 96.7 bits (239), Expect = 4e-25
Identities = 103/404 (25%), Positives = 171/404 (42%), Gaps = 32/404 (8%)
Query 14 LMFPLALVLFEFAVYIGNDLIQPAMLAITQDFAVSATWAPSSMSFYLLGGACVAWLLGPL 73
L+ ALVL A G D+ + I D S + S YL G A G +
Sbjct 5 LICSFALVLLYPA---GIDMYLVGLPRIAADLNASEAQLHIAFSVYLAGMAAAMLFAGKV 61
Query 74 SDRLGRKRVLLFGVLFFALCCLLILLTHNMAQFLALRFLQGIGLSVITAVGYAAIQETFE 133
+DR GRK V + G F + + L FLA RFLQG+G V +A +++T +
Sbjct 62 ADRSGRKPVAIPGAALFIIASVFCSLAETSTLFLAGRFLQGLGAGCCYVVAFAILRDTLD 121
Query 134 ERDAIKVMALMANISLLAPLLGPVLGAFLIDYVSWHWGFVAIATLA----GLSWFGLKAK 189
+R KV++L+ I+ + P+L PVLG ++ W F A+A + LS F LK
Sbjct 122 DRRRAKVLSLLNGITCIIPVLAPVLGHLIMLKFPWQSLFWAMAMMGIAVLMLSLFILKET 181
Query 190 MPSQQHSVTRQPFVYLFDDFKKIYLDKRFLGLSLGLPLVGMPLMLWIALSPVMLVDELKF 249
P+ + + + + L++ FL + L ++ ++ SPV+L++ + F
Sbjct 182 RPAAPAASDKP------RENSESLLNRFFLSRVVITTLSVSVILTFVNTSPVLLMEIMGF 235
Query 250 SSVQYGLAQFPIFMGLILGNIVLIKIIDRFPLGKTILMGLPIMLVGTLVLLVGAIWQDYL 309
+Y M L G + + F LG I +M+ ++ L I L
Sbjct 236 ERGEYA-----TIMALTAGVSMTVSFSTPFALG--IFKPRTLMITSQVLFLAAGI---TL 285
Query 310 AV-----CLLVGMTLISFGEGISFSVIYRFALMSSPVAKGTVAA--AVSMLLMFSFFIMI 362
AV L G+TLI G + F V AL + G ++ ++ + S +I +
Sbjct 286 AVSPSHAVSLFGITLICAGFSVGFGVAMSQALGPFSLRAGVASSTLGIAQVCGSSLWIWL 345
Query 363 ELVRELYVHFHVLAFSLSC--VVLITLWFLLPRLMLKQEMAIRH 404
V + ++ ++C V L+ + F+ P + I H
Sbjct 346 AAVVGIGAWNMLIGILIACSIVSLLLIMFVAPGRPVAAHEEIHH 389
>P32482 Chloramphenicol resistance protein [Pseudomonas aeruginosa]
Length=419
Score = 89.7 bits (221), Expect = 1e-22
Identities = 76/340 (22%), Positives = 147/340 (43%), Gaps = 20/340 (6%)
Query 18 LALVLFEFAVYIGNDLIQPAMLAITQDFAVSATWAPSSMSFYLLGGACVAWLLGPLSDRL 77
L L F+ +G D+ PA+ + +A+ +++ YL+ L GPLSDRL
Sbjct 17 LLLSPFDLLASLGMDMYLPAVPFMPNALGTTASTIQLTLTTYLVMIGAGQLLFGPLSDRL 76
Query 78 GRKRVLLFGVLFFALCCLLILLTHNMAQFLALRFLQGIGLSVITAVGYAAIQETFEERDA 137
GR+ VLL G L + + + + LT + FL LR LQ G S +A +++ + R+
Sbjct 77 GRRPVLLGGGLAYVVASMGLALTSSAEVFLGLRILQACGASACLVSTFATVRDIYAGREE 136
Query 138 IKVM-ALMANISLLAPLLGPVLGAFLIDYVSWH-------WGFVAIATLAGLSWFGLKA- 188
V+ ++ ++ + P +GP+LGA + ++ W G +A + A W +
Sbjct 137 SNVIYGILGSMLAMVPAVGPLLGALVDMWLGWRAIFAFLGLGMIAASAAAWRFWPETRVQ 196
Query 189 KMPSQQHSVTRQPFVYLFDDFKKIYLDKRFLGLSLGLPLVGMPLMLWIALSPVMLVDELK 248
++ Q S P L +L +G ++ +++P +++
Sbjct 197 RVAGLQWSQLLLPVKCL-----NFWLYTLCYAAGMG------SFFVFFSIAPGLMMGRQG 245
Query 249 FSSVQYGLAQFPIFMGLILGNIVLIKIIDRFPLGKTILMGLPIMLVGTLVLLVGAIWQDY 308
S + + L + + ++ + ++I ++ + MG+ ++ G ++L + IW
Sbjct 246 VSQLGFSLLFATVAIAMVFTARFMGRVIPKWGSPSVLRMGMGCLIAGAVLLAITEIWALQ 305
Query 309 LAVCLLVGMTLISFGEGISFSVIYRFALMSSPVAKGTVAA 348
+ + M L+ G + SV AL GTV A
Sbjct 306 SVLGFIAPMWLVGIGVATAVSVAPNGALRGFDHVAGTVTA 345
>P96712 Multidrug resistance protein 3 [Bacillus subtilis (strain
168)]
Length=512
Score = 85.1 bits (209), Expect = 6e-21
Identities = 54/181 (30%), Positives = 82/181 (45%), Gaps = 5/181 (3%)
Query 6 TTTLNRTTLMFPLALVLFEFAVYIGNDLIQPAMLAITQDFAV--SATWAPSSMSFYLLGG 63
TT +T L L+L + N ++ AM I D W +S ++ G
Sbjct 4 TTAKQASTKFVVLGLLLGILMSAMDNTIVATAMGNIVADLGSFDKFAWVTASYMVAVMAG 63
Query 64 ACVAWLLGPLSDRLGRKRVLLFGVLFFALCCLLILLTHNMAQFLALRFLQGIGLSVITAV 123
+ G LSD GRKR LFG++FF + L + M Q + R +QGIG + +
Sbjct 64 MPI---YGKLSDMYGRKRFFLFGLIFFLIGSALCGIAQTMNQLIIFRAIQGIGGGALLPI 120
Query 124 GYAAIQETFEERDAIKVMALMANISLLAPLLGPVLGAFLIDYVSWHWGFVAIATLAGLSW 183
+ I + F K+ + + L+ +LGP+LGA + D +SWHW F + LS
Sbjct 121 AFTIIFDLFPPEKRGKMSGMFGAVFGLSSVLGPLLGAIITDSISWHWVFYINVPIGALSL 180
Query 184 F 184
F
Sbjct 181 F 181
Score = 20.4 bits (41), Expect = 2.3
Identities = 15/54 (28%), Positives = 29/54 (54%), Gaps = 6/54 (11%)
Query 140 VMALMANISLLAPLLGPV---LGAFLIDYVSWHWGFVAIATLAGLSWFGLKAKM 190
+M+ M N +++A +G + LG+F D +W +A +AG+ +G + M
Sbjct 23 LMSAMDN-TIVATAMGNIVADLGSF--DKFAWVTASYMVAVMAGMPIYGKLSDM 73
>P31474 Probable transport protein HsrA [Escherichia coli (strain
K12)]
Length=475
Score = 80.5 bits (197), Expect = 2e-19
Identities = 80/335 (24%), Positives = 144/335 (43%), Gaps = 31/335 (9%)
Query 33 LIQPAMLAITQDFAVSATWAPSSMSFYLLGGACVAWLLGPLSDRLGRKRVLLFGVLFFAL 92
++ A+ AI S S++ Y L A + + G L+DR G +R+ V F L
Sbjct 29 ILNTALPAIAHSLNRSPLAMQSAIISYTLTVAMLIPVSGWLADRFGTRRIFTLAVSLFTL 88
Query 93 CCLLILLTHNMAQFLALRFLQGIGLSVITAVGYAAIQETFEERDAIKVMALMANISLLAP 152
L L++++ Q + R +QGIG +++ V A+ + + + V+ +A L+ P
Sbjct 89 GSLACALSNSLPQLVVFRVIQGIGGAMMMPVARLALLRAYPRNELLPVLNFVAMPGLVGP 148
Query 153 LLGPVLGAFLIDYVSWHWGFVAIATLAGLSWFGLKAKMPSQQHSVTRQPFVYLFDDFKKI 212
+LGPVLG L+ + +WHW F+ + G+ + +++H FD +
Sbjct 149 ILGPVLGGVLVTWATWHWIFLINIPI------GIAGLLYARKHMPNFTTARRRFDITGFL 202
Query 213 YLDKRFLGLSLGLPLVGMPLML-WIALSPV------MLVDELKFSSVQYGLAQFPIFMGL 265
+ S G+ L G ++ WIAL+ + +L+ L L +F
Sbjct 203 LFGLSLVLFSSGIELFGEKIVASWIALTVIVTSIGLLLLYILHARRTPNPLISLDLFKTR 262
Query 266 ILGNIVLIKIIDRFPLGKTILMGLPIMLVGTLVLLVGAIWQDYLAVCLLVGMTLISFGEG 325
++ I R G +P ++ L+L VG +Q ++A C++ L G
Sbjct 263 TFSIGIVGNIATRLGTG-----CVPFLM--PLMLQVGFGYQAFIAGCMMAPTAL---GSI 312
Query 326 ISFSVI--------YRFALMSSPVAKGTVAAAVSM 352
I+ S++ YR L+ V G + A S+
Sbjct 313 IAKSMVTQVLRRLGYRHTLVGITVIIGLMIAQFSL 347
Score = 21.9 bits (45), Expect = 0.74
Identities = 10/29 (34%), Positives = 18/29 (62%), Gaps = 0/29 (0%)
Query 14 LMFPLALVLFEFAVYIGNDLIQPAMLAIT 42
L+F L+LVLF + + + I + +A+T
Sbjct 202 LLFGLSLVLFSSGIELFGEKIVASWIALT 230
Score = 18.9 bits (37), Expect = 6.8
Identities = 10/38 (26%), Positives = 15/38 (39%), Gaps = 13/38 (34%)
Query 177 TLAGLSWFG-------------LKAKMPSQQHSVTRQP 201
++AGL W L +P+ HS+ R P
Sbjct 8 SMAGLPWIAAMAFFMQALDATILNTALPAIAHSLNRSP 45
>S0DS64 Trichosetin biosynthesis cluster MFS transporter [Gibberella
fujikuroi (strain CBS 195.34 / IMI 58289 / NRRL A-6831)]
Length=481
Score = 79.0 bits (193), Expect = 6e-19
Identities = 47/161 (29%), Positives = 78/161 (48%), Gaps = 1/161 (1%)
Query 22 LFEFAVYIGNDLIQPAMLAITQDFAV-SATWAPSSMSFYLLGGACVAWLLGPLSDRLGRK 80
L A + + P ++ +F + SAT ++S Y+LG A LL PLS+ GR
Sbjct 79 LSTLAANLAATMFAPGAAELSDEFNITSATVTAMTVSLYVLGFALGPLLLAPLSELYGRL 138
Query 81 RVLLFGVLFFALCCLLILLTHNMAQFLALRFLQGIGLSVITAVGYAAIQETFEERDAIKV 140
+ F + + + + N+A FL R + G S ++G + + F + K
Sbjct 139 IIYHFCNMVYMAFTIGCAFSTNVAMFLVFRIIAGCAASGPMSIGGGTVADLFVQEQRGKA 198
Query 141 MALMANISLLAPLLGPVLGAFLIDYVSWHWGFVAIATLAGL 181
MAL A LL P++GP++G F+ + V W W F + L+G+
Sbjct 199 MALFAVGPLLGPVIGPIIGGFVSENVGWRWTFRILLILSGI 239
Score = 19.2 bits (38), Expect = 5.1
Identities = 23/88 (26%), Positives = 40/88 (45%), Gaps = 10/88 (11%)
Query 156 PVLGAFLIDYVSWHWGFVAI-ATLAGLSWFGLKAKMPSQ-QHSVTRQPFVYLFDDFKKIY 213
P++G F++ + S FV I + + FG +A + + + R PF D +
Sbjct 383 PIIGTFIVGFGSL---FVVIPGQIYLVDAFGAEAAASAMAANLLVRSPFGAFLDLTAEPL 439
Query 214 LDKRFLGLSLGLPLVGMPLMLWIALSPV 241
K LGL G ++G + +A +PV
Sbjct 440 YSK--LGLGWGNSVLG---FITLAFTPV 462
Score = 18.9 bits (37), Expect = 6.8
Identities = 8/27 (30%), Positives = 11/27 (41%), Gaps = 0/27 (0%)
Query 51 WAPSSMSFYLLGGACVAWLLGPLSDRL 77
W S + F L V W+ +RL
Sbjct 447 WGNSVLGFITLAFTPVPWIFYTYGERL 473
Lambda K H a alpha
0.334 0.146 0.450 0.792 4.96
Gapped
Lambda K H a alpha sigma
0.267 0.0410 0.140 1.90 42.6 43.6
Effective search space used: 3007011
Database: d6e2e64d3ceb3ce2f46b472c7b3e9104.SwissProt.fasta
Posted date: May 9, 2024 5:39 AM
Number of letters in database: 9,642
Number of sequences in database: 23
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Neighboring words threshold: 11
Window for multiple hits: 40
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Data ...
