BLASTP 2.12.0+
Reference: Stephen F. Altschul, Thomas L. Madden, Alejandro A.
Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J.
Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of
protein database search programs", Nucleic Acids Res. 25:3389-3402.
Reference for composition-based statistics: Alejandro A. Schaffer,
L. Aravind, Thomas L. Madden, Sergei Shavirin, John L. Spouge, Yuri
I. Wolf, Eugene V. Koonin, and Stephen F. Altschul (2001),
"Improving the accuracy of PSI-BLAST protein database searches with
composition-based statistics and other refinements", Nucleic Acids
Res. 29:2994-3005.
Database: f70693fe60bc4504feb9b878cf849eb8.SwissProt.fasta
11 sequences; 5,712 total letters
Query= ACIAD3230
Length=414
Score E
Sequences producing significant alignments: (Bits) Value
Q22682 Putative sodium-dependent excitatory amino acid transporte... 245 9e-80
O59010 Glutamate transporter homolog [Pyrococcus horikoshii (stra... 234 4e-76
P31597 Excitatory amino acid transporter 3 [Oryctolagus cuniculus] 220 6e-70
P43005 Excitatory amino acid transporter 3 [Homo sapiens] 218 7e-69
P51906 Excitatory amino acid transporter 3 [Mus musculus] 217 9e-69
Q95135 Excitatory amino acid transporter 3 [Bos taurus] 216 2e-68
P51907 Excitatory amino acid transporter 3 [Rattus norvegicus] 216 3e-68
P56564 Excitatory amino acid transporter 1 [Mus musculus] 214 2e-67
P24942 Excitatory amino acid transporter 1 [Rattus norvegicus] 213 4e-67
P43003 Excitatory amino acid transporter 1 [Homo sapiens] 213 8e-67
P46411 Excitatory amino acid transporter 1 [Bos taurus] 212 2e-66
>Q22682 Putative sodium-dependent excitatory amino acid transporter
glt-4 [Caenorhabditis elegans]
Length=499
Score = 245 bits (626), Expect = 9e-80
Identities = 164/443 (37%), Positives = 243/443 (55%), Gaps = 51/443 (12%)
Query 8 LIAAILGIGFGFILNLYPQTAFFSTSLYTLGIISSIFIGLLKMLLVPLIFTSIVVGVSNL 67
++ ++GIG GF L P A+ L L +F+ +LKML++P+I +SI+ +++L
Sbjct 15 VLGVVVGIGLGFSLR-DPSKAWSKRHLSYLRFPGDLFVQMLKMLILPMIMSSIITSLASL 73
Query 68 QASGQFGRVWKITALCCFVTTTFALILGIGCAHLFGVGKGMDIAIFSEAMSQH------- 120
SG GR+ ++ + +TT FA+ LGI + GK I E + H
Sbjct 74 D-SGTAGRLGMVSMIYYTLTTFFAVFLGIVLVSVIKPGKWTTTNI--EDLVGHVKTTPCV 130
Query 121 -QAPDT---LSPSAFFTNFIQNTLIN---------------------------------P 143
A DT L S F N I+ T + P
Sbjct 131 ATAVDTIIDLMKSCFPENLIEATFRSQKICLKFFNGTTEIPPEIAMTMSPEQRAQFTEVP 190
Query 144 FKAFSEG-NVLAVVVFALLIGAALIKGGERFQSVRILSLQLFDIMMMLVGWVMKLAPLGI 202
K S+G N+L +VVF++ +G + GE + ++ L M L+GWV+ +P+GI
Sbjct 191 EKIVSDGMNILGLVVFSVALGIVIGVIGEDGKPMKNFFKSLEACSMKLIGWVIIYSPVGI 250
Query 203 LALLA-KLIATEDL-KILGSLAEFALVVTGTTIFHGAVVLPLLLWIFGKMNPITFFKGTR 260
L+A +++ +D + L L + + V + H VV+PLL + + NPI F G
Sbjct 251 TFLIAAQIVGMKDPGQELHRLMGYVITVILGLLIHAFVVIPLLCVVLARRNPIKFVGGMA 310
Query 261 LALITAFATSSSSATMPLSMKCAQENLKVRPQTAGFVIPLGTQLNMDGTALYEAAAALFI 320
AL+TA ATSSSSAT+PLS+KC +EN KV P+ FV+PLG +NMDGTALYEA AA++I
Sbjct 311 QALLTALATSSSSATLPLSIKCCEENNKVDPRVTRFVLPLGATINMDGTALYEAVAAIYI 370
Query 321 ANLVGLDLSLTQQLIVCLTAMIASLGAPGIPSAGMVTMIMVLQSVGLPAEAIAILLPIDR 380
+ G DLSL + ++V LTA +AS+GA GIP AG+VTMIMVL ++GLP ++ P+D
Sbjct 371 SQCYGNDLSLGEVVLVSLTATLASIGAAGIPQAGIVTMIMVLIAIGLPTNLFILIFPVDF 430
Query 381 ILDTVRTVVNVQGDMMISVVVDR 403
+LD +RT VNV GD + + V++R
Sbjct 431 MLDRLRTTVNVHGDSIATAVIER 453
Score = 18.9 bits (37), Expect = 4.1
Identities = 18/85 (21%), Positives = 35/85 (41%), Gaps = 6/85 (7%)
Query 281 KCAQENLKVRPQTAGFVIPLGTQLNMDGTALYEAAAALFIANLVG------LDLSLTQQL 334
K ++ENL + G V+ +G ++ + + L G L + + +
Sbjct 3 KLSKENLLLLFTVLGVVVGIGLGFSLRDPSKAWSKRHLSYLRFPGDLFVQMLKMLILPMI 62
Query 335 IVCLTAMIASLGAPGIPSAGMVTMI 359
+ + +ASL + GMV+MI
Sbjct 63 MSSIITSLASLDSGTAGRLGMVSMI 87
>O59010 Glutamate transporter homolog [Pyrococcus horikoshii (strain
ATCC 700860 / DSM 12428 / JCM 9974 / NBRC 100139 / OT-3)]
Length=425
Score = 234 bits (596), Expect = 4e-76
Identities = 152/411 (37%), Positives = 233/411 (57%), Gaps = 28/411 (7%)
Query 6 QILIAAILGIGFGFILNLYPQTAFFSTSLYTLGIISSIFIGLLKMLLVPLIFTSIVVGVS 65
+ILI ILG G IL Y T + G +F+ LLKML++P++F S+VVG +
Sbjct 15 KILIGLILGAIVGLILGHYGYADAVKTYVKPFG---DLFVRLLKMLVMPIVFASLVVGAA 71
Query 66 NLQASGQFGRVWKITALCCFVTTTFALILGIGCAHLFGVGKGMDIAIFSEAMSQHQAPDT 125
++ + + GRV + +T+ FA+ LGI A LF G G+ +A+ + QAP
Sbjct 72 SISPA-RLGRVGVKIVVYYLLTSAFAVTLGIIMARLFNPGAGIHLAVGGQQFQPKQAPPL 130
Query 126 LSPSAFFTNFIQNTLINPFKAFSEGNVLAVVVFALLIGAAL--IKGGERFQSVRILSLQL 183
+ + NPF A + G VL + FA+++G A+ + E + VR + L
Sbjct 131 VKI------LLDIVPTNPFGALANGQVLPTIFFAIILGIAITYLMNSEN-EKVRKSAETL 183
Query 184 FDI-------MMMLVGWVMKLAPLGILALLAKLIATEDLKILGSLAEFALVVTGTTIFHG 236
D M +V VM+ AP+G+ AL+A ++A + +K++G LA+ V
Sbjct 184 LDAINGLAEAMYKIVNGVMQYAPIGVFALIAYVMAEQGVKVVGELAKVTAAVYVGLTLQI 243
Query 237 AVVLPLLLWIFGKMNPITFFKGTRLALITAFATSSSSATMPLSMKCAQENLKVRPQTAGF 296
+V +LL I+G ++PI+F K + A++TAF T SSS T+P++M+ A+E + + F
Sbjct 244 LLVYFVLLKIYG-IDPISFIKKAKDAMLTAFVTRSSSGTLPVTMRVAKE-MGISEGIYSF 301
Query 297 VIPLGTQLNMDGTALYEAAAALFIANLVGLDLSLTQQLIVCLTAMIASLGAPGIPSAGMV 356
+PLG +NMDGTALY+ FIAN +G L++ QQL + LTA++AS+G G+P AG +
Sbjct 302 TLPLGATINMDGTALYQGVCTFFIANALGSHLTVGQQLTIVLTAVLASIGTAGVPGAGAI 361
Query 357 TMIMVLQSVGLP------AEAIAILLPIDRILDTVRTVVNVQGDMMISVVV 401
+ MVL+SVGLP A A A++L ID ILD RT+VNV GD+ + +V
Sbjct 362 MLAMVLESVGLPLTDPNVAAAYAMILGIDAILDMGRTMVNVTGDLTGTAIV 412
>P31597 Excitatory amino acid transporter 3 [Oryctolagus cuniculus]
Length=524
Score = 220 bits (561), Expect = 6e-70
Identities = 147/443 (33%), Positives = 232/443 (52%), Gaps = 50/443 (11%)
Query 8 LIAAILGIGFGFILNLYPQTAFFSTSLYTLGIISSIFIGLLKMLLVPLIFTSIVVGVSNL 67
++A +LGI G ++ Y + + + I + +LK++++PLI +S++ GV+ L
Sbjct 25 VVAVVLGIVIGVLVREYSNLS--TLDKFYFAFPGEILMRMLKLVILPLIVSSMITGVAAL 82
Query 68 QASGQFGRVWKITALCCFVTTTFALILGIGCA------------HLFGVGKGMDIAIFSE 115
S G++ L F TT A+ILGI + G +++
Sbjct 83 D-SNVSGKIGLRAVLYYFCTTIIAVILGIVLVVSIKPGVTQKVDEIDRTGSTPEVSTVDA 141
Query 116 AMS--QHQAPDTL----------------------------SPSAFFTNFIQNTLINPFK 145
+ ++ P+ L S +A T + ++
Sbjct 142 MLDLIRNMFPENLVQACFQQYKTTREEVTASDDTGKNGTEESVTAVMTTAVSENRTKEYR 201
Query 146 A---FSEG-NVLAVVVFALLIGAALIKGGERFQSVRILSLQLFDIMMMLVGWVMKLAPLG 201
+S+G NVL ++VF L+ G + K GE+ Q + L D M +V +M PLG
Sbjct 202 VVGLYSDGINVLGLIVFCLVFGLVIGKMGEKGQILVDFFNALSDATMKIVQIIMCYMPLG 261
Query 202 ILALLA-KLIATEDLKILGSLAEFALVVTGTTIFHGAVVLPLLLWIFGKMNPITFFKGTR 260
IL L+A K+I ED +I L + + V H V+LPL+ +I + NP F G
Sbjct 262 ILFLIAGKIIEVEDWEIFRKLGLYMVTVLSGLAIHSIVILPLIYFIVVRKNPFRFAMGMT 321
Query 261 LALITAFATSSSSATMPLSMKCAQENLKVRPQTAGFVIPLGTQLNMDGTALYEAAAALFI 320
AL+TA SSSSAT+P++ +CA+E +V + FV+P+G +NMDGTALYEA AA+FI
Sbjct 322 QALLTALMISSSSATLPVTFRCAEEKNRVDKRITRFVLPVGATINMDGTALYEAVAAVFI 381
Query 321 ANLVGLDLSLTQQLIVCLTAMIASLGAPGIPSAGMVTMIMVLQSVGLPAEAIAILLPIDR 380
A L +DLS+ Q + + +TA AS+GA G+P AG+VTM++VL +VGLPAE + +++ +D
Sbjct 382 AQLNDMDLSIGQIITISVTATAASIGAAGVPQAGLVTMVIVLSAVGLPAEDVTLIIAVDW 441
Query 381 ILDTVRTVVNVQGDMMISVVVDR 403
+LD RTVVNV GD + +V++
Sbjct 442 LLDRFRTVVNVLGDAFGTGIVEK 464
>P43005 Excitatory amino acid transporter 3 [Homo sapiens]
Length=524
Score = 218 bits (554), Expect = 7e-69
Identities = 152/442 (34%), Positives = 234/442 (53%), Gaps = 52/442 (12%)
Query 10 AAILGIGFGFILNLYPQTAFFSTSLYTLGIISSIFIGLLKMLLVPLIFTSIVVGVSNLQA 69
A +LGI G ++ + + + + I + +LK++++PLI +S++ GV+ L
Sbjct 27 AVVLGITTGVLVREHSNLS--TLEKFYFAFPGEILMRMLKLIILPLIISSMITGVAALD- 83
Query 70 SGQFGRVWKITALCCFVTTTFALILGI--------GCAHLFG----VGKGMDIAIFSEAM 117
S G++ + F TT A+ILGI G G G +++ +
Sbjct 84 SNVSGKIGLRAVVYYFCTTLIAVILGIVLVVSIKPGVTQKVGEIARTGSTPEVSTVDAML 143
Query 118 S--QHQAPDTLSPSAF----------------------------FTNFIQNTLINPFKA- 146
++ P+ L + F T I +K
Sbjct 144 DLIRNMFPENLVQACFQQYKTKREEVKPPSDPEMNMTEESFTAVMTTAISKNKTKEYKIV 203
Query 147 --FSEG-NVLAVVVFALLIGAALIKGGERFQSVRILSLQLFDIMMMLVGWVMKLAPLGIL 203
+S+G NVL ++VF L+ G + K GE+ Q + L D M +V +M PLGIL
Sbjct 204 GMYSDGINVLGLIVFCLVFGLVIGKMGEKGQILVDFFNALSDATMKIVQIIMCYMPLGIL 263
Query 204 ALLA-KLIATEDLKILGSLAEF-ALVVTGTTIFHGAVVLPLLLWIFGKMNPITFFKGTRL 261
L+A K+I ED +I L + A V+TG I H V+LPL+ +I + NP F G
Sbjct 264 FLIAGKIIEVEDWEIFRKLGLYMATVLTGLAI-HSIVILPLIYFIVVRKNPFRFAMGMAQ 322
Query 262 ALITAFATSSSSATMPLSMKCAQENLKVRPQTAGFVIPLGTQLNMDGTALYEAAAALFIA 321
AL+TA SSSSAT+P++ +CA+EN +V + FV+P+G +NMDGTALYEA AA+FIA
Sbjct 323 ALLTALMISSSSATLPVTFRCAEENNQVDKRITRFVLPVGATINMDGTALYEAVAAVFIA 382
Query 322 NLVGLDLSLTQQLIVCLTAMIASLGAPGIPSAGMVTMIMVLQSVGLPAEAIAILLPIDRI 381
L LDL + Q + + +TA AS+GA G+P AG+VTM++VL +VGLPAE + +++ +D +
Sbjct 383 QLNDLDLGIGQIITISITATSASIGAAGVPQAGLVTMVIVLSAVGLPAEDVTLIIAVDWL 442
Query 382 LDTVRTVVNVQGDMMISVVVDR 403
LD RT+VNV GD + +V++
Sbjct 443 LDRFRTMVNVLGDAFGTGIVEK 464
>P51906 Excitatory amino acid transporter 3 [Mus musculus]
Length=523
Score = 217 bits (553), Expect = 9e-69
Identities = 145/440 (33%), Positives = 230/440 (52%), Gaps = 49/440 (11%)
Query 10 AAILGIGFGFILNLYPQTAFFSTSLYTLGIISSIFIGLLKMLLVPLIFTSIVVGVSNLQA 69
A +LGI G ++ + + + + + I + +LK++++PLI +S++ GV+ L
Sbjct 27 AVVLGIVLGVVVRGHSELS--NLDKFYFAFPGEILMRMLKLVILPLIVSSMITGVAALD- 83
Query 70 SGQFGRVWKITALCCFVTTTFALILGIGCA------------HLFGVGKGMDIAIFSEAM 117
S G++ + F TT A+ILGI + GK +++ +
Sbjct 84 SNVSGKIGLRAVVYYFSTTVIAVILGIVLVVSIKPGVTQKVNDINRTGKTPEVSTMDAML 143
Query 118 S--QHQAPDTLSPSAFFTNFIQNTLINPFK------------------------------ 145
++ P+ L + F + + P
Sbjct 144 DLIRNMFPENLVQACFQQYKTKREEVKPVGDPGGNATEVSVTTAMTTMSENKTKEYKIVG 203
Query 146 AFSEG-NVLAVVVFALLIGAALIKGGERFQSVRILSLQLFDIMMMLVGWVMKLAPLGILA 204
+S+G NVL +++F L+ G + K GE+ Q + L D M +V +M P+GIL
Sbjct 204 LYSDGINVLGLIIFCLVFGLVIGKMGEKGQILVDFFNALSDATMKIVQIIMCYMPIGILF 263
Query 205 LLA-KLIATEDLKILGSLAEFALVVTGTTIFHGAVVLPLLLWIFGKMNPITFFKGTRLAL 263
L+A K+I ED +I L + V H +VLPLL +I + NP F G AL
Sbjct 264 LIAGKIIEVEDWEIFRKLGLYMATVLSGLAIHSLIVLPLLYFIVVRKNPFRFALGMAQAL 323
Query 264 ITAFATSSSSATMPLSMKCAQENLKVRPQTAGFVIPLGTQLNMDGTALYEAAAALFIANL 323
+TA SSSSAT+P++ +CA+E +V + FV+P+G +NMDGTALYEA AA+FIA L
Sbjct 324 LTALMISSSSATLPVTFRCAEEKNQVDKRITRFVLPVGATINMDGTALYEAVAAVFIAQL 383
Query 324 VGLDLSLTQQLIVCLTAMIASLGAPGIPSAGMVTMIMVLQSVGLPAEAIAILLPIDRILD 383
GLDLS+ Q + + +TA AS+GA G+P AG+VTM++VL +VGLPAE + +++ +D +LD
Sbjct 384 NGLDLSIGQIVTISITATAASIGAAGVPQAGLVTMVIVLSAVGLPAEDVTLIIAVDWLLD 443
Query 384 TVRTVVNVQGDMMISVVVDR 403
RT+VNV GD + +V++
Sbjct 444 RFRTMVNVLGDAFGTGIVEK 463
>Q95135 Excitatory amino acid transporter 3 [Bos taurus]
Length=524
Score = 216 bits (551), Expect = 2e-68
Identities = 150/444 (34%), Positives = 234/444 (53%), Gaps = 52/444 (12%)
Query 8 LIAAILGIGFGFILNLYPQTAFFSTSLYTLGIISSIFIGLLKMLLVPLIFTSIVVGVSNL 67
++A +LGI G ++ Y + + + + I + +LK++++PLI +S++ GV+ L
Sbjct 25 VVAVVLGIVIGVLVREYSKLS--NLEKFYFSFPGEILMRMLKLVILPLIVSSMITGVATL 82
Query 68 QASGQFGRVWKITALCCFVTTTFALILGI---------------------GCAHLFGVGK 106
S G++ + F TT A+ILGI + V
Sbjct 83 D-SNVSGKIGLRAVVYYFCTTLIAVILGIVLVVSIKPGVTQKVNEIDRTGNTPEVSTVDA 141
Query 107 GMDIA--IFSEAMSQ---------------HQAPDTLSPSAFFTNFIQNTLINPFKA--- 146
+D+ +F E + Q + P T S A T I T I+ K
Sbjct 142 MLDLIRNMFPENLVQACFQQYKTTREEVELSEEPGTNSTEATVTA-IMTTAISKNKTKEY 200
Query 147 -----FSEG-NVLAVVVFALLIGAALIKGGERFQSVRILSLQLFDIMMMLVGWVMKLAPL 200
+S+G NVL ++VF L++G + + E+ Q + L D M +V +M P+
Sbjct 201 KVVGMYSDGINVLGLIVFCLVLGIVIGRKWEKGQILVDFFNALSDATMKIVQIIMCYMPI 260
Query 201 GILALLA-KLIATEDLKILGSLAEFALVVTGTTIFHGAVVLPLLLWIFGKMNPITFFKGT 259
GIL L+A K+I ED +I L + V H V+LPL+ +I + NP F G
Sbjct 261 GILFLIAGKIIEVEDWEIFRKLGLYMATVLSGLAIHSIVILPLIYFIIVRKNPFQFAMGM 320
Query 260 RLALITAFATSSSSATMPLSMKCAQENLKVRPQTAGFVIPLGTQLNMDGTALYEAAAALF 319
AL+TA SSSSAT+P++ +CA+E +V + FV+P+G +NMDGTALYEA AA+F
Sbjct 321 AQALLTALMISSSSATLPVTFRCAEEKNRVDKRITRFVLPVGATINMDGTALYEAVAAVF 380
Query 320 IANLVGLDLSLTQQLIVCLTAMIASLGAPGIPSAGMVTMIMVLQSVGLPAEAIAILLPID 379
IA L LDLS+ Q + + +TA AS+GA G+P G+VTM++VL +VGLPAE + +++ +D
Sbjct 381 IAQLNDLDLSVGQIITISVTATAASIGAAGVPQPGLVTMVIVLSAVGLPAEDVTLIIAVD 440
Query 380 RILDTVRTVVNVQGDMMISVVVDR 403
+LD RT+VNV GD + +V++
Sbjct 441 WLLDRFRTMVNVLGDAFGTGIVEK 464
>P51907 Excitatory amino acid transporter 3 [Rattus norvegicus]
Length=523
Score = 216 bits (549), Expect = 3e-68
Identities = 144/440 (33%), Positives = 229/440 (52%), Gaps = 49/440 (11%)
Query 10 AAILGIGFGFILNLYPQTAFFSTSLYTLGIISSIFIGLLKMLLVPLIFTSIVVGVSNLQA 69
A +LGI G ++ + + + + + I + +LK++++PLI +S++ GV+ L
Sbjct 27 AVVLGIVVGVLVRGHSELS--NLDKFYFAFPGEILMRMLKLVILPLIISSMITGVAALD- 83
Query 70 SGQFGRVWKITALCCFVTTTFALILGIGCA------------HLFGVGKGMDIAIFSEAM 117
S G++ + F TT A+ILGI + GK +++ +
Sbjct 84 SNVSGKIGLRAVVYYFSTTVIAVILGIVLVVSIKPGVTQKVNEINRTGKTPEVSTVDAML 143
Query 118 S--QHQAPDTLSPSAFFTNFIQNTLINPFK------------------------------ 145
++ P+ L + F + + P
Sbjct 144 DLIRNMFPENLVQACFQQYKTKREEVKPASDPGGNQTEVSVTTAMTTMSENKTKEYKIVG 203
Query 146 AFSEG-NVLAVVVFALLIGAALIKGGERFQSVRILSLQLFDIMMMLVGWVMKLAPLGILA 204
+S+G NVL +++F L+ G + K GE+ Q + L D M +V +M P+GIL
Sbjct 204 LYSDGINVLGLIIFCLVFGLVIGKMGEKGQILVDFFNALSDATMKIVQIIMCYMPIGILF 263
Query 205 LLA-KLIATEDLKILGSLAEFALVVTGTTIFHGAVVLPLLLWIFGKMNPITFFKGTRLAL 263
L+A K+I ED +I L + V H VVLPL+ +I + NP F G AL
Sbjct 264 LIAGKIIEVEDWEIFRKLGLYMATVLSGLAIHSLVVLPLIYFIVVRKNPFRFALGMAQAL 323
Query 264 ITAFATSSSSATMPLSMKCAQENLKVRPQTAGFVIPLGTQLNMDGTALYEAAAALFIANL 323
+TA SSSSAT+P++ +CA+E V + FV+P+G +NMDGTALYEA AA+FIA L
Sbjct 324 LTALMISSSSATLPVTFRCAEEKNHVDKRITRFVLPVGATINMDGTALYEAVAAVFIAQL 383
Query 324 VGLDLSLTQQLIVCLTAMIASLGAPGIPSAGMVTMIMVLQSVGLPAEAIAILLPIDRILD 383
G+DLS+ Q + + +TA AS+GA G+P AG+VTM++VL +VGLPAE + +++ +D +LD
Sbjct 384 NGMDLSIGQIITISITATAASIGAAGVPQAGLVTMVIVLSAVGLPAEDVTLIIAVDWLLD 443
Query 384 TVRTVVNVQGDMMISVVVDR 403
RT+VNV GD + +V++
Sbjct 444 RFRTMVNVLGDAFGTGIVEK 463
>P56564 Excitatory amino acid transporter 1 [Mus musculus]
Length=543
Score = 214 bits (545), Expect = 2e-67
Identities = 150/451 (33%), Positives = 238/451 (53%), Gaps = 64/451 (14%)
Query 5 TQILIAAILGIGFGFILNLYPQTAFFSTSLYTLGIISSIFIGLLKMLLVPLIFTSIVVGV 64
T +++ ILG Y + +FS + + +L+ML++PLI +S+V G+
Sbjct 56 TAVIVGTILGFALRPYKMSYREVKYFSFP-------GELLMRMLQMLVLPLIISSLVTGM 108
Query 65 SNL--QASGQFGRVWKITALCCFVTTTF-ALILGIGCAHLFGVGKGMDIAIFSEA----- 116
+ L +ASG+ G + A+ ++TTT A+++GI + GKG ++ E
Sbjct 109 AALDSKASGKMG----MRAVVYYMTTTIIAVVIGIIIVIIIHPGKGTKENMYREGKIVQV 164
Query 117 --------MSQHQAPDTLSPSAFF---TNFIQNTLINPFKA-----------FSEG---- 150
+ ++ P L + F T++ + + P ++ SE
Sbjct 165 TAADAFLDLIRNMFPPNLVEACFKQFKTSYEKRSFKVPIQSNETLLGAVINNVSEAMETL 224
Query 151 -----------------NVLAVVVFALLIGAALIKGGERFQSVRILSLQLFDIMMMLVGW 193
N L +VVF++ G + E+ Q++R L + +M LV
Sbjct 225 TRIREEMVPVPGSVNGVNALGLVVFSMCFGFVIGNMKEQGQALREFFDSLNEAIMRLVAV 284
Query 194 VMKLAPLGILALLA-KLIATEDLKILGS-LAEFALVVTGTTIFHGAVVLPLLLWIFGKMN 251
+M APLGIL L+A K++ ED+ ++G LA + + V + H +VLPLL ++ + N
Sbjct 285 IMWYAPLGILFLIAGKIVEMEDMGVIGGQLAMYTVTVIVGLLIHAVIVLPLLYFLVTRKN 344
Query 252 PITFFKGTRLALITAFATSSSSATMPLSMKCAQENLKVRPQTAGFVIPLGTQLNMDGTAL 311
P F G ALITA TSSSSAT+P++ KC +EN V + FV+P+G +NMDGTAL
Sbjct 345 PWVFIGGLLQALITALGTSSSSATLPITFKCLEENNGVDKRITRFVLPVGATINMDGTAL 404
Query 312 YEAAAALFIANLVGLDLSLTQQLIVCLTAMIASLGAPGIPSAGMVTMIMVLQSVGLPAEA 371
YEA AA+FIA + DL+ Q + + +TA AS+GA GIP AG+VTM++VL SVGLP +
Sbjct 405 YEALAAIFIAQVNNFDLNFGQIITISITATAASIGAAGIPQAGLVTMVIVLTSVGLPTDD 464
Query 372 IAILLPIDRILDTVRTVVNVQGDMMISVVVD 402
I +++ +D LD +RT NV GD + + +V+
Sbjct 465 ITLIIAVDWFLDRLRTTTNVLGDSLGAGIVE 495
>P24942 Excitatory amino acid transporter 1 [Rattus norvegicus]
Length=543
Score = 213 bits (543), Expect = 4e-67
Identities = 150/449 (33%), Positives = 237/449 (53%), Gaps = 64/449 (14%)
Query 7 ILIAAILGIGFGFILNLYPQTAFFSTSLYTLGIISSIFIGLLKMLLVPLIFTSIVVGVSN 66
+++ ILG Y + +FS + + +L+ML++PLI +S+V G++
Sbjct 58 VIVGTILGFALRPYKMSYREVKYFSFP-------GELLMRMLQMLVLPLIISSLVTGMAA 110
Query 67 L--QASGQFGRVWKITALCCFVTTTF-ALILGIGCAHLFGVGKGMDIAIFSEA------- 116
L +ASG+ G + A+ ++TTT A+++GI + GKG ++ E
Sbjct 111 LDSKASGKMG----MRAVVYYMTTTIIAVVIGIIIVIIIHPGKGTKENMYREGKIVQVTA 166
Query 117 ------MSQHQAPDTLSPSAFF---TNFIQNTLINPFKA-----------FSEG------ 150
+ ++ P L + F T++ + + P +A SE
Sbjct 167 ADAFLDLIRNMFPPNLVEACFKQFKTSYEKRSFKVPIQANETLLGAVINNVSEAMETLTR 226
Query 151 ---------------NVLAVVVFALLIGAALIKGGERFQSVRILSLQLFDIMMMLVGWVM 195
N L +VVF++ G + E+ Q++R L + +M LV +M
Sbjct 227 IREEMVPVPGSVNGVNALGLVVFSMCFGFVIGNMKEQGQALREFFDSLNEAIMRLVAVIM 286
Query 196 KLAPLGILALLA-KLIATEDLKILGS-LAEFALVVTGTTIFHGAVVLPLLLWIFGKMNPI 253
APLGIL L+A K++ ED+ ++G LA + + V + H +VLPLL ++ + NP
Sbjct 287 WYAPLGILFLIAGKILEMEDMGVIGGQLAMYTVTVIVGLLIHAVIVLPLLYFLVTRKNPW 346
Query 254 TFFKGTRLALITAFATSSSSATMPLSMKCAQENLKVRPQTAGFVIPLGTQLNMDGTALYE 313
F G ALITA TSSSSAT+P++ KC +EN V + FV+P+G +NMDGTALYE
Sbjct 347 VFIGGLLQALITALGTSSSSATLPITFKCLEENNGVDKRITRFVLPVGATINMDGTALYE 406
Query 314 AAAALFIANLVGLDLSLTQQLIVCLTAMIASLGAPGIPSAGMVTMIMVLQSVGLPAEAIA 373
A AA+FIA + DL+ Q + + +TA AS+GA GIP AG+VTM++VL SVGLP + I
Sbjct 407 ALAAIFIAQVNNFDLNFGQIITISITATAASIGAAGIPQAGLVTMVIVLTSVGLPTDDIT 466
Query 374 ILLPIDRILDTVRTVVNVQGDMMISVVVD 402
+++ +D LD +RT NV GD + + +V+
Sbjct 467 LIIAVDWFLDRLRTTTNVLGDSLGAGIVE 495
>P43003 Excitatory amino acid transporter 1 [Homo sapiens]
Length=542
Score = 213 bits (541), Expect = 8e-67
Identities = 150/451 (33%), Positives = 237/451 (53%), Gaps = 64/451 (14%)
Query 5 TQILIAAILGIGFGFILNLYPQTAFFSTSLYTLGIISSIFIGLLKMLLVPLIFTSIVVGV 64
T +++ ILG Y + +FS + + +L+ML++PLI +S+V G+
Sbjct 56 TAVIVGTILGFTLRPYRMSYREVKYFSFP-------GELLMRMLQMLVLPLIISSLVTGM 108
Query 65 SNL--QASGQFGRVWKITALCCFVTTTF-ALILGIGCAHLFGVGKGMDIAIFSEA----- 116
+ L +ASG+ G + A+ ++TTT A+++GI + GKG + E
Sbjct 109 AALDSKASGKMG----MRAVVYYMTTTIIAVVIGIIIVIIIHPGKGTKENMHREGKIVRV 164
Query 117 --------MSQHQAPDTLSPSAFF---TNFIQNTLINPFKA-----------FSEG---- 150
+ ++ P L + F TN+ + + P +A SE
Sbjct 165 TAADAFLDLIRNMFPPNLVEACFKQFKTNYEKRSFKVPIQANETLVGAVINNVSEAMETL 224
Query 151 -----------------NVLAVVVFALLIGAALIKGGERFQSVRILSLQLFDIMMMLVGW 193
N L +VVF++ G + E+ Q++R L + +M LV
Sbjct 225 TRITEELVPVPGSVNGVNALGLVVFSMCFGFVIGNMKEQGQALREFFDSLNEAIMRLVAV 284
Query 194 VMKLAPLGILALLA-KLIATEDLKILGS-LAEFALVVTGTTIFHGAVVLPLLLWIFGKMN 251
+M AP+GIL L+A K++ ED+ ++G LA + + V + H +VLPLL ++ + N
Sbjct 285 IMWYAPVGILFLIAGKIVEMEDMGVIGGQLAMYTVTVIVGLLIHAVIVLPLLYFLVTRKN 344
Query 252 PITFFKGTRLALITAFATSSSSATMPLSMKCAQENLKVRPQTAGFVIPLGTQLNMDGTAL 311
P F G ALITA TSSSSAT+P++ KC +EN V + FV+P+G +NMDGTAL
Sbjct 345 PWVFIGGLLQALITALGTSSSSATLPITFKCLEENNGVDKRVTRFVLPVGATINMDGTAL 404
Query 312 YEAAAALFIANLVGLDLSLTQQLIVCLTAMIASLGAPGIPSAGMVTMIMVLQSVGLPAEA 371
YEA AA+FIA + +L+ Q + + +TA AS+GA GIP AG+VTM++VL SVGLP +
Sbjct 405 YEALAAIFIAQVNNFELNFGQIITISITATAASIGAAGIPQAGLVTMVIVLTSVGLPTDD 464
Query 372 IAILLPIDRILDTVRTVVNVQGDMMISVVVD 402
I +++ +D LD +RT NV GD + + +V+
Sbjct 465 ITLIIAVDWFLDRLRTTTNVLGDSLGAGIVE 495
>P46411 Excitatory amino acid transporter 1 [Bos taurus]
Length=542
Score = 212 bits (539), Expect = 2e-66
Identities = 150/451 (33%), Positives = 236/451 (52%), Gaps = 64/451 (14%)
Query 5 TQILIAAILGIGFGFILNLYPQTAFFSTSLYTLGIISSIFIGLLKMLLVPLIFTSIVVGV 64
T +++ ILG Y + +FS + + +L+ML++PLI +S+V G+
Sbjct 56 TAVIVGTILGFTLRPYRMSYREVKYFSFP-------GELLMRMLQMLVLPLIISSLVTGM 108
Query 65 SNL--QASGQFGRVWKITALCCFVTTTF-ALILGIGCAHLFGVGKGMDIAIFSEA----- 116
+ L +ASG+ G + A+ ++TTT A+++GI + GKG + E
Sbjct 109 AALDSKASGKMG----MRAVVYYMTTTIIAVVIGIIIVIIIHPGKGTKENMHREGKIVQV 164
Query 117 --------MSQHQAPDTLSPSAFF---TNFIQNTLINPFKA-----------FSEG---- 150
+ ++ P L + F TN+ + + P + SE
Sbjct 165 TAADAFLDLIRNMFPPNLVEACFKQFKTNYEKRSFKVPIQPNETLVGAVINNVSEAMETL 224
Query 151 -----------------NVLAVVVFALLIGAALIKGGERFQSVRILSLQLFDIMMMLVGW 193
N L +VVF++ G + E+ Q++R L + +M LV
Sbjct 225 TRITEELVPVPGSVNGVNALGLVVFSMCFGFVIGNMKEQGQALREFFDSLNEAIMRLVAV 284
Query 194 VMKLAPLGILALLA-KLIATEDLKILGS-LAEFALVVTGTTIFHGAVVLPLLLWIFGKMN 251
+M APLGIL L+A K++ ED+ ++G LA + + V + H +VLPLL ++ + N
Sbjct 285 IMWYAPLGILFLIAGKIVEMEDMGVIGGQLAMYTVTVIVGLLIHAVIVLPLLYFLVTRKN 344
Query 252 PITFFKGTRLALITAFATSSSSATMPLSMKCAQENLKVRPQTAGFVIPLGTQLNMDGTAL 311
P F G ALITA TSSSSAT+P++ KC +EN V + FV+P+G +NMDGTAL
Sbjct 345 PWVFIGGLLQALITALGTSSSSATLPITFKCLEENNGVDKRVTRFVLPVGATINMDGTAL 404
Query 312 YEAAAALFIANLVGLDLSLTQQLIVCLTAMIASLGAPGIPSAGMVTMIMVLQSVGLPAEA 371
YEA AA+FIA + +L+ Q + + +TA AS+GA GIP AG+VTM++VL SVGLP +
Sbjct 405 YEALAAIFIAQVNNFELNFGQIITISITATAASIGAAGIPQAGLVTMVIVLTSVGLPTDD 464
Query 372 IAILLPIDRILDTVRTVVNVQGDMMISVVVD 402
I +++ +D LD +RT NV GD + + +V+
Sbjct 465 ITLIIAVDWFLDRLRTTTNVLGDSLGAGIVE 495
Lambda K H a alpha
0.329 0.141 0.406 0.792 4.96
Gapped
Lambda K H a alpha sigma
0.267 0.0410 0.140 1.90 42.6 43.6
Effective search space used: 1878968
Database: f70693fe60bc4504feb9b878cf849eb8.SwissProt.fasta
Posted date: May 31, 2024 10:41 AM
Number of letters in database: 5,712
Number of sequences in database: 11
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Neighboring words threshold: 11
Window for multiple hits: 40
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Data ...
