BLASTP 2.12.0+
Reference: Stephen F. Altschul, Thomas L. Madden, Alejandro A.
Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J.
Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of
protein database search programs", Nucleic Acids Res. 25:3389-3402.
Reference for composition-based statistics: Alejandro A. Schaffer,
L. Aravind, Thomas L. Madden, Sergei Shavirin, John L. Spouge, Yuri
I. Wolf, Eugene V. Koonin, and Stephen F. Altschul (2001),
"Improving the accuracy of PSI-BLAST protein database searches with
composition-based statistics and other refinements", Nucleic Acids
Res. 29:2994-3005.
Database: 0378d9b96e337ad3dc978764ba8e38bd.SwissProt.fasta
11 sequences; 7,240 total letters
Query= ACIAD0015
Length=652
Score E
Sequences producing significant alignments: (Bits) Value
P44569 NAD 5'-nucleotidase [Haemophilus influenzae (strain ATCC 5... 296 3e-95
O83142 Probable 5'-nucleotidase [Treponema pallidum (strain Nicho... 292 1e-93
P29240 5'-nucleotidase [Diplobatis ommata] 196 5e-58
Q61503 5'-nucleotidase [Mus musculus] 187 8e-55
O34313 2',3'-cyclic-nucleotide 2'-phosphodiesterase/3'-nucleotida... 191 3e-54
P21588 5'-nucleotidase [Rattus norvegicus] 159 9e-45
A0A2I4HXH5 Snake venom 5'-nucleotidase [Naja atra] 154 2e-43
Q05927 5'-nucleotidase [Bos taurus] 153 7e-43
P21589 5'-nucleotidase [Homo sapiens] 153 7e-43
F8S0Z7 Snake venom 5'-nucleotidase [Crotalus adamanteus] 150 9e-42
B6EWW8 Snake venom 5'-nucleotidase [Gloydius brevicaudus] 147 7e-41
>P44569 NAD 5'-nucleotidase [Haemophilus influenzae (strain ATCC
51907 / DSM 11121 / KW20 / Rd)]
Length=603
Score = 296 bits (759), Expect = 3e-95
Identities = 192/572 (34%), Positives = 302/572 (53%), Gaps = 39/572 (7%)
Query 61 LKIIHINDHHSHLDEERMEFDLNTGSTSGTYSVSRGGFARVSALFNQLAMGHGAILKLHA 120
L I+HINDHHS+L+ +LN T V GGF+ V+A N+L + L LHA
Sbjct 37 LSILHINDHHSYLEPHETRINLNGQQTK----VDIGGFSAVNAKLNKLRKKYKNPLVLHA 92
Query 121 GDATTGDLYYNLTKGKADADVMNMICFDAFTLGNHEFDNKDQGLKYFIDALDQGDCPTRT 180
GDA TG LY+ L G ADA VMN F FTLGNHEFD ++GL ++ P +
Sbjct 93 GDAITGTLYFTLFGGSADAAVMNAGNFHYFTLGNHEFDAGNEGLLKLLE-------PLKI 145
Query 181 AILSANVEFGPSSPLYQSTRIQKSTVIETQGQKIGLVGLTIAQKTKNASQPNPDTLFKDE 240
+LSANV +S LY + + G+KI ++GL KT N+S P D F DE
Sbjct 146 PVLSANVIPDKNSILYNKWK--PYDIFTVDGEKIAIIGLDTVNKTVNSSSPGKDVKFYDE 203
Query 241 LESAQQQIDLLRQAGINKIILQSHVGYEMDKYLATQLHGVDVIVGGDSHTLLGSQNLEKV 300
+ +AQ + L+Q GINKIIL SH G E + +A +++ +DVIV GDSH L G+ L +
Sbjct 204 IATAQIMANALKQQGINKIILLSHAGSEKNIEIAQKVNDIDVIVTGDSHYLYGNDELRSL 263
Query 301 GMTPEAPYPTTLQNKDGDPVCIVQAWQYSYVVGELDITFDSQGRVKNCQGTPHILIGDDF 360
+ YP +N +GDPV +++ W YS VVG+L + F +G + PH+L+
Sbjct 264 KLPVIYEYPLEFKNPNGDPVFVMEGWAYSAVVGDLGVKFSPEGIASITRKIPHVLM-SSH 322
Query 361 KPKLTSAPA----LTHDQQLNIAKQLHLLAPEITVIEPDSRTSQILSPYRDMKEKFRQTI 416
K ++ +A LT D++ L + I++ + D++T ++S Y+ K++ Q I
Sbjct 323 KLQVKNAEGKWTELTGDERKKALDTLKSM-KSISLDDHDAKTDMLISKYKSEKDRLAQEI 381
Query 417 VATAQEILCLRRVPGTQRDINRSSLGNVCNQDERVNRYGGDIQQLVAEAFLQQGKTYFSA 476
V ++ +PG + + G+ N G + +AE + KT
Sbjct 382 VG----VITGSAMPGGSANRIPNKAGS--------NPEGSIATRFIAETMYNELKT---V 426
Query 477 QLSILNGGGVRTDVEQGPISVEKVYQVLPYNSTLVQLNMQGNEIKATLEDAVDAVITLNN 536
L+I N GGVR D+ G ++ Y LP+ +TL M+G+ +K LEDA+ + +
Sbjct 427 DLTIQNAGGVRADILPGNVTFNDAYTFLPFGNTLYTYKMEGSLVKQVLEDAMQFALVDGS 486
Query 537 TGSYPYTAGLRWSV-DFNQPKGQRISNIE-LKDSSGEYSLLMMDQTYRVVTLDFLANGSD 594
TG++PY AG+R+ + +G+R+ ++E L + ++ + ++ Y V T ++A G D
Sbjct 487 TGAFPYGAGIRYEANETPNAEGKRLVSVEVLNKQTQQWEPIDDNKRYLVGTNAYVAGGKD 546
Query 595 YYHTLATIRNERR---IDVGLDYAEAFMKYLE 623
Y T + N+ + +D L AE+F+K+++
Sbjct 547 GYKTFGKLFNDPKYEGVDTYLPDAESFIKFMK 578
>O83142 Probable 5'-nucleotidase [Treponema pallidum (strain Nichols)]
Length=593
Score = 292 bits (748), Expect = 1e-93
Identities = 190/581 (33%), Positives = 307/581 (53%), Gaps = 39/581 (7%)
Query 53 NSASDDSSLKIIHINDHHSHLDEERMEFDLNTGSTSGTYSVSRGGFARVSALFNQLAMGH 112
+S + D L IIHINDHHSHL+ E +E + + GG+A + +L
Sbjct 26 DSRAGDFELTIIHINDHHSHLEPEPLELAV----AGERLRAAVGGYAALVHEIQRLRAES 81
Query 113 GAILKLHAGDATTGDLYYNLTKGKADADVMNMICFDAFTLGNHEFDNKDQGLKYFIDALD 172
L LHAGDA G LY L +G+ADA +MN FD FTLGNHEFDN ++GLK F+ L+
Sbjct 82 KNALVLHAGDALIGTLYSTLFRGRADAVLMNHAGFDFFTLGNHEFDNGNEGLKEFLHYLE 141
Query 173 QGDCPTRTAILSANVEFGPSSPLYQSTRIQKSTVIETQGQKIGLVGLTIAQKTKNASQPN 232
+LSANV +S L+ + S ++E G++IG++GL +KT +S P
Sbjct 142 -------VPVLSANVVPNAASTLHGLWK--PSAIVERAGERIGVIGLDTVKKTVESSSPG 192
Query 233 PDTLFKDELESAQQQIDLLRQAGINKIILQSHVGYEMDKYLATQLHGVDVIVGGDSHTLL 292
D F DE+E+ ++ ++Q G+NKIIL SH G+E + +A + G+DVIV GD+H LL
Sbjct 193 KDINFIDEIEAVRRATVEMQQQGVNKIILLSHAGFEKNCEIAQNISGIDVIVSGDTHYLL 252
Query 293 GSQNLEKVGMTPEAPYPTTLQNKDGDPVCIVQAWQYSYVVGELDITFDSQGRVKNCQGTP 352
G ++L ++G+ YP + + G+PV +V+AW+Y +GEL++ FD G + + G P
Sbjct 253 GDESLGRLGLPVVGEYPRKIMSPAGEPVYVVEAWEYGKCLGELNVVFDRTGVITSAVGMP 312
Query 353 HILIGDDFKPKLTSAPALTHDQQLNIAKQLHLL-----APEITVIEPDSRTSQILSPYRD 407
L+ + L A + L A++ LL PEI + + + +L ++
Sbjct 313 RFLLHTN---TLQKKGADRKNYPLEEAEREALLVALRMTPEIIFAQENDQIISVLEEFKK 369
Query 408 MKEKFRQTIVATAQEILCLRRVPGTQRDINRSSLGNVCNQDERVNRYGGDIQQLVAEAFL 467
KE + A A ++ + G G+V + N G + VAE L
Sbjct 370 EKE----ALGAQAIGVITGASMRG----------GSVHRVPDAQNPQGSVATRFVAETML 415
Query 468 QQGKTYFSAQLS--ILNGGGVRTDVEQGPISVEKVYQVLPYNSTLVQLNMQGNEIKATLE 525
+++ + ++ I N GG R++++ G I+ Y +LP+++TLV +++ G E+K +E
Sbjct 416 SDIQSFGAGKVDCVIQNAGGARSNIQPGEITYNDAYTLLPFSNTLVLVDVSGAELKQIIE 475
Query 526 DAVDAVITLNNTGSYPYTAGLRWSVDFNQPK-GQRISNIELKDSSGEYSLLMMDQTYRVV 584
DA+ + +TG++PY AG+R+ + G+R+ +E++ G + + YR+
Sbjct 476 DALQFALGDGSTGAFPYGAGVRYEARQEPDEHGKRVIKLEVQKKDGAWVPVDERAPYRLG 535
Query 585 TLDFLANGSDYYHTLATIRNERRI-DVGLDYAEAFMKYLEA 624
++A G D Y TL I + R D L AE+ +K+L A
Sbjct 536 VNSYIARGKDGYKTLGEIVSTRGAEDTYLRDAESLIKFLRA 576
>P29240 5'-nucleotidase [Diplobatis ommata]
Length=577
Score = 196 bits (498), Expect = 5e-58
Identities = 157/571 (27%), Positives = 260/571 (46%), Gaps = 77/571 (13%)
Query 61 LKIIHINDHHSHLDEERMEFDLNTGSTSGT-YSVSRGGFARVSALFNQLAMGHGAILKLH 119
L I+H ND H+ ++E T SG ++ S G AR +L +L L
Sbjct 32 LTILHTNDVHARVEE--------TNQDSGKCFTQSFAGVARRWTKIEELRARDKNVLLLD 83
Query 120 AGDATTGDLYYNLTKGKADADVMNMICFDAFTLGNHEFDNKDQGLKYFIDALDQGDCPTR 179
AGD G +++N KG A + + ++A LGNHEFDN +GL LD
Sbjct 84 AGDQYQGTIWFNYYKGAEAAHFIEAVGYNAMALGNHEFDNGAEGL------LDPFLLNVS 137
Query 180 TAILSANVEFGPSSPLYQSTRIQKSTVIETQGQKIGLVGLTIAQKTKNASQPNPDTLFKD 239
+LSAN+E G + STV++ G+KIG+VG T +++T S P P +FKD
Sbjct 138 FPVLSANLEQGEDQVPSLIGYYKPSTVLDVNGEKIGVVGYT-SKETPTLSSPGPHLIFKD 196
Query 240 ELESAQQQIDLLRQAGINKIILQSHVGYEMDKYLATQLHGVDVIVGGDSHTLLGSQNLEK 299
E+++ Q ++D+L GI+KII H G+E DK +A ++ GVDV+VGG S+T L +
Sbjct 197 EIQAVQHEVDILVSQGIDKIIALGHSGFETDKLIAQKVRGVDVVVGGHSNTFLYTGKAPS 256
Query 300 VGMTPEAPYPTTLQNKDGDPVCIVQAWQYSYVVGELDITFDSQGRVKNCQGTPHILIGDD 359
P PYP + + D + +VQA+ Y +G L +TFD +G V +G P +L
Sbjct 257 -NDVPVGPYPFLVNSDDQRTIPVVQAYAYGKYLGYLKLTFD-KGEVIKREGNPILL---- 310
Query 360 FKPKLTSAPALTHDQQLNIAKQLHLLAPEITVIEPDSRTSQILSPYRDMKEKFRQTIVAT 419
+ P L + ++ +++ F + ++
Sbjct 311 -NSSIIQDPVLLAE----------------------------VNKWKESLANFGKEVIGR 341
Query 420 AQEILCLRRVPGTQRDINRSSLGNVCNQDERVNRYGGDIQQLVAEAFLQQGKTYFSAQLS 479
L R+ N +L +C+ IQQ + K + +
Sbjct 342 TVVYLNGTTEECRNRECNMGNL--ICD---------AMIQQNIRN---PDEKFWNHVSIC 387
Query 480 ILNGGGVRTDVEQ---GPISVEKVYQVLPYNSTLVQLNMQGNEIKATLEDAVDAVITLNN 536
I GGG+R + + G I V+ + VLP+ ST+ L + G+ ++A + +V N
Sbjct 388 IFQGGGIRAPINEQNNGTIQVDSLLAVLPFGSTIDLLEVYGSTLRAAFDHSVRRY--GQN 445
Query 537 TGSYPYTAGLRWSVDFNQPKGQRISNIELKDSS---GEYSLLMMDQTYRVVTLDFLANGS 593
TG + +G++ + +P G R+ I++ + Y L+ ++ Y++VT ++A G
Sbjct 446 TGEFLQVSGIQVQFNLKRPPGSRVVKIDVLCADCRVPHYQPLLDNKIYKIVTNSYIAEGG 505
Query 594 DYYHTLATIRNER-RIDVGLDYAEAFMKYLE 623
D + ++NER R D G Y++
Sbjct 506 DGF---TMLKNERLRYDTGSTDISVVSSYIK 533
>Q61503 5'-nucleotidase [Mus musculus]
Length=576
Score = 187 bits (475), Expect = 8e-55
Identities = 157/555 (28%), Positives = 251/555 (45%), Gaps = 68/555 (12%)
Query 51 PENSASDDSSLKIIHINDHHSHLDEERMEFDLNTGSTSGTYSVSRGGFARVSALFNQLAM 110
P+ A+ L I+H ND HS L++ D +T + + V GG AR+ Q+
Sbjct 21 PQWPAASAWELTILHTNDVHSRLEQTS---DDSTKCLNASLCV--GGVARLFTKVQQIRK 75
Query 111 GHGAILKLHAGDATTGDLYYNLTKGKADADVMNMICFDAFTLGNHEFDNKDQGLKYFIDA 170
+L L AGD G +++ + KG A MN++ +DA LGNHEFDN +GL ID
Sbjct 76 EEPNVLFLDAGDQYQGTIWFTVYKGLEVAHFMNILGYDAMALGNHEFDNGVEGL---IDP 132
Query 171 LDQGDCPTRTAILSANVEFGPSSPLYQSTRIQKSTVIETQGQKIGLVGLTIAQKTKNASQ 230
L + + ILSAN++ S S V+ G+ +G+VG T +++T S
Sbjct 133 LLRN---VKFPILSANIKARGPLAHQISGLFLPSKVLSVGGEVVGIVGYT-SKETPFLSN 188
Query 231 PNPDTLFKDELESAQQQIDLLRQAGINKIILQSHVGYEMDKYLATQLHGVDVIVGGDSHT 290
P + +F+DE+ + Q ++D L+ +NKII H G+EMDK +A ++ GVD++VGG S+T
Sbjct 189 PGTNLVFEDEISALQPEVDKLKTLNVNKIIALGHSGFEMDKLIAQKVRGVDIVVGGHSNT 248
Query 291 LLGSQNLEKVGMTPEAPYPTTLQNKDGDPVCIVQAWQYSYVVGELDITFDSQGRVKNCQG 350
L + N + P YP + DG V +VQA+ + +G L + FD +G V G
Sbjct 249 FLYTGNPPSKEV-PAGKYPFIVTADDGRQVPVVQAYAFGKYLGYLKVEFDDKGNVITSYG 307
Query 351 TPHILIGDDFKPKLTSAPALTHDQQLNIAKQLHLLAPEITVIEPDSRTSQILSPYRDMKE 410
P + L+ PE I+ D +I +E
Sbjct 308 NPIL---------------------------LNSSIPEDATIKADINQWRIKLDNYSTQE 340
Query 411 KFRQTIVATAQEILCLRRVPGTQRDINRSSLGNVCNQDERVNRYGGDIQQLVAEAFLQQG 470
R + C R+ N +L +C+ N D E F
Sbjct 341 LGRTIVYLDGSTQTC------RFRECNMGNL--ICDAMINNNLRHPD------EMF---- 382
Query 471 KTYFSAQLSILNGGGVRTDVEQ---GPISVEKVYQVLPYNSTLVQLNMQGNEIKATLEDA 527
+ + I+NGGG+R+ +++ G I+ E + VLP+ T + ++G+ +K E +
Sbjct 383 --WNHVSMCIVNGGGIRSPIDEKNNGTITWENLAAVLPFGGTFDLVQLKGSTLKKAFEHS 440
Query 528 VDAVITLNNTGSYPYTAGLRWSVDFNQPKGQRISNIEL---KDSSGEYSLLMMDQTYRVV 584
V +TG + G+ D N+ R+ +E+ K Y L MD+ Y+V
Sbjct 441 VHRY--GQSTGEFLQVGGIHVVYDINRKPWNRVVQLEVLCTKCRVPIYEPLEMDKVYKVT 498
Query 585 TLDFLANGSDYYHTL 599
+LANG D + +
Sbjct 499 LPSYLANGGDGFQMI 513
>O34313 2',3'-cyclic-nucleotide 2'-phosphodiesterase/3'-nucleotidase
/ 5'-nucleotidase [Bacillus subtilis (strain 168)]
Length=1462
Score = 191 bits (484), Expect = 3e-54
Identities = 153/601 (25%), Positives = 252/601 (42%), Gaps = 122/601 (20%)
Query 50 PPENSASDDSSLKIIHINDHHSHLDEERMEFDLNTGSTSGTYSVSRGGFARVSALFNQLA 109
PP++ D L ++H ND H+HLD+ AR N++
Sbjct 661 PPKDGLWD---LTVMHTNDTHAHLDDA----------------------ARRMTKINEVR 695
Query 110 MGHGAILKLHAGDATTGDLYYNLTKGKADADVMNMICFDAFTLGNHEFDNKDQGLKYFID 169
+ L AGD +GDLY+ G AD +MNM+ +DA T GNHEFD L F+
Sbjct 696 SETNHNILLDAGDVFSGDLYFTKWNGLADLKMMNMMGYDAMTFGNHEFDKGPTVLSDFLS 755
Query 170 ALDQGDCPTRT--------AILSANVEFGPSSPLYQSTR--------------IQKSTVI 207
P I+SANV+ L + I ++
Sbjct 756 GNSATVDPANRYHFEAPEFPIVSANVDVSNEPKLKSFVKKPQTFTAGEKKEAGIHPYILL 815
Query 208 ETQGQKIGLVGLTIAQKTKNASQPNPDTLFKDELESAQQQIDLLR-QAGINKIILQSHVG 266
+ G+K+ + GLT + T S P +F D E+AQ + ++ + +NKII +H+G
Sbjct 816 DVDGEKVAVFGLT-TEDTATTSSPGKSIVFNDAFETAQNTVKAIQEEEKVNKIIALTHIG 874
Query 267 YEMDKYLATQLHGVDVIVGGDSHTLLGSQNLEKVGMTPEAPYPTTLQNKDGDPVCIVQAW 326
+ D LA ++ G+D+I+GG +HTL+ + + +P + QA
Sbjct 875 HNRDLELAKKVKGIDLIIGGHTHTLVDKMEVV----------------NNEEPTIVAQAK 918
Query 327 QYSYVVGELDITFDSQGRVKNCQGTPHILIGDDFKPKLTSAPALTHDQQLNIAKQLHLLA 386
+Y +G +D+ FD +G V+ K L+ P H ++ AKQ
Sbjct 919 EYGQFLGRVDVAFDEKGVVQT------------DKSNLSVLPIDEHTEENPEAKQ----- 961
Query 387 PEITVIEPDSRTSQILSPYRDMK-EKFRQTIVATAQEILCLRRVPGTQRDINRSSLGNVC 445
Q + D+K EK T VA +
Sbjct 962 ----------ELDQFKNELEDVKNEKVGYTDVA-------------------------LD 986
Query 446 NQDERVNRYGGDIQQLVAEAFLQQGKTYFSAQLSILNGGGVRTDVEQGPISVEKVYQVLP 505
Q E V ++ +A+ L + K A+++I NGGG+R +++G I++ +V V+P
Sbjct 987 GQREHVRTKETNLGNFIADGMLAKAKEAAGARIAITNGGGIRAGIDKGDITLGEVLNVMP 1046
Query 506 YNSTLVQLNMQGNEIKATLEDAVDAVITLNNTGSYPYTAGLRWSVDFNQPKGQRISNIEL 565
+ +TL ++ G +IK LE + V N G++P AG+ ++ N G R+ +++
Sbjct 1047 FGNTLYVADLTGKQIKEALEQGLSNV--ENGGGAFPQVAGIEYTFTLNNKPGHRVLEVKI 1104
Query 566 KDSSGEYSLLMMDQTYRVVTLDFLANGSDYYHTLATIRNERRIDVGLDYAEAFMKYLEAD 625
+ +G+ + D TYRV T +F+ G D Y + D+G E F + L+
Sbjct 1105 ESPNGDKVAINTDDTYRVATNNFVGAGGDGYSVFTEASHGE--DLGYVDYEIFTEQLKKL 1162
Query 626 G 626
G
Sbjct 1163 G 1163
Score = 81.6 bits (200), Expect = 4e-19
Identities = 137/599 (23%), Positives = 233/599 (39%), Gaps = 115/599 (19%)
Query 46 TTVIPPENSASDDSSLKIIHINDHHSHLDEERMEFDLNTGSTSGTYSVSRGGFARVSALF 105
T I E SA+ L I+ D H+++ M++D + + + G AR + L
Sbjct 30 TPPIHAEESAAPQVHLSILATTDIHANM----MDYDYYSDKETADF-----GLARTAQLI 80
Query 106 NQLAMGHGAILKLHAGDATTG------------DLYYNLTKGKADADVMNMICFDAFTLG 153
+ + L + GD G D + TK VMN + +DA TLG
Sbjct 81 QKHREQNPNTLLVDNGDLIQGNPLGEYAVKYQKDDIISGTKTHPIISVMNALKYDAGTLG 140
Query 154 NHEFDNKDQGLKYFIDALDQGDCPTRTAILSANVEFGPSSPLYQSTRIQKSTVIETQGQ- 212
NHEF + GL + + D P I++ANV+ Y I + T+I+ G
Sbjct 141 NHEF---NYGLDFLDGTIKGADFP----IVNANVKTTSGENRYTPYVINEKTLIDENGNE 193
Query 213 ---KIGLVGLTIAQ-KTKNASQPNPDTLFKDELESAQQQIDLLRQAGINKIILQSHVGYE 268
K+G +G Q T + +D +ESA + I ++ G + II +H G E
Sbjct 194 QKVKVGYIGFVPPQIMTWDKKNLEGQVQVQDIVESANETIPKMKAEGADVIIALAHTGIE 253
Query 269 MDKY----------LATQLHGVDVIVGGDSHTLLGSQNLEKVGMTPEAPYPTTLQNKDGD 318
LAT+ G+D I+ G H L S V A + +G
Sbjct 254 KQAQSSGAENAVFDLATKTKGIDAIISGHQHGLFPSAEYAGV-----AQFNVEKGTINGI 308
Query 319 PVCIVQAWQYSYVVGELDITF---DSQGRVKNCQGTPHILIGDDFKPKLTSAPALTHDQQ 375
PV + +W +G +D+ D +V + +G+ + G+ +TS ++
Sbjct 309 PVVMPSSW--GKYLGVIDLKLEKADGSWKVADSKGSIESIAGN-----VTS----RNETV 357
Query 376 LNIAKQLHLLAPEITVIEPDSRT-SQILSPYRDMKEKFRQTIVATAQEILCLRRVPGTQR 434
N +Q H E V +P +T + I S + +K+ IV AQ+ + + T+
Sbjct 358 TNTIQQTHQNTLEY-VRKPVGKTEADINSFFAQVKDDPSIQIVTDAQKWYAEKEMKDTEY 416
Query 435 DINRSSLGNVCNQDERVNRYGGDIQQLVAEAFLQQGKTYFSAQLSILNGGGVRTDVEQGP 494
++ L A A + G NG T++ G
Sbjct 417 K---------------------NLPILSAGAPFKAGGR---------NGANYYTNIPAGD 446
Query 495 ISVEKVYQVLPYNSTLVQLNMQGNEIKATLEDAV------------DAVITLNNTGSYPY 542
++++ V + Y++T+ + + G+E+K LE + D + N SY +
Sbjct 447 LAIKNVGDLYLYDNTVQIVKLTGSEVKDWLEMSAGQFNQIDPAKGGDQALLNENFRSYNF 506
Query 543 TA--GLRWSVDFNQP-KGQRISNIELKDSSGEYSL------LMMDQTYRVVTLDFLANG 592
G+ + VD +P K + DSS +L + Q + VVT ++ A+G
Sbjct 507 DVIDGVTYQVDVTKPAKYNENGKVINADSSRIINLSYEGKPISPSQEFLVVTNNYRASG 565
>P21588 5'-nucleotidase [Rattus norvegicus]
Length=576
Score = 159 bits (401), Expect = 9e-45
Identities = 104/296 (35%), Positives = 161/296 (54%), Gaps = 15/296 (5%)
Query 61 LKIIHINDHHSHLDEERMEFDLNTGSTSGTYSVSRGGFARVSALFNQLAMGHGAILKLHA 120
L I+H ND HS L++ D +T + + V GG AR+ Q+ +L L A
Sbjct 31 LTIMHTNDVHSRLEQTS---DDSTKCLNASLCV--GGVARLFTKVQQIRKEEPNVLLLDA 85
Query 121 GDATTGDLYYNLTKGKADADVMNMICFDAFTLGNHEFDNKDQGLKYFIDALDQGDCPTRT 180
GD G +++ + KG A MN++ +DA LGNHEFDN +GL ID L + +
Sbjct 86 GDQYQGTIWFTVYKGLEVAHFMNLLGYDAMALGNHEFDNGVEGL---IDPLLRN---VKF 139
Query 181 AILSANVEF-GPSSPLYQSTRIQKSTVIETQGQKIGLVGLTIAQKTKNASQPNPDTLFKD 239
ILSAN++ GP +P + V+ G+ +G+VG T +++T S P + +F+D
Sbjct 140 PILSANIKARGPLAPQISGLYLPYK-VLSVGGEVVGIVGYT-SKETPFLSNPGTNLVFED 197
Query 240 ELESAQQQIDLLRQAGINKIILQSHVGYEMDKYLATQLHGVDVIVGGDSHTLLGSQNLEK 299
E+ + Q ++D L+ +NKII H G+EMDK +A ++ GVDV+VGG ++T L + N
Sbjct 198 EVTALQPEVDKLKTLNVNKIIALGHSGFEMDKLIAQKVRGVDVVVGGHTNTFLYTGNPPS 257
Query 300 VGMTPEAPYPTTLQNKDGDPVCIVQAWQYSYVVGELDITFDSQGRVKNCQGTPHIL 355
+ P YP + + DG V +VQA+ + +G L + FD +G V G P +L
Sbjct 258 KEV-PAGKYPFIVTSDDGRKVPVVQAYAFGKYLGYLKVEFDDKGNVVTSYGNPILL 312
Score = 53.9 bits (128), Expect = 1e-10
Identities = 34/128 (27%), Positives = 64/128 (50%), Gaps = 8/128 (6%)
Query 478 LSILNGGGVRTDVEQ---GPISVEKVYQVLPYNSTLVQLNMQGNEIKATLEDAVDAVITL 534
+ I+NGGG+R+ +++ G I+ E + VLP+ T + ++G+ +K E +V
Sbjct 388 MCIVNGGGIRSPIDERNNGTITWENLAAVLPFGGTFDLVQLKGSTLKKAFEHSVHRYG-- 445
Query 535 NNTGSYPYTAGLRWSVDFNQPKGQRISNIEL---KDSSGEYSLLMMDQTYRVVTLDFLAN 591
+TG + G+ D ++ R+ +++ K Y L MD+ Y+VV +L N
Sbjct 446 QSTGEFLQVGGIHVVYDISRKPWDRVVQLKVLCTKCRVPIYEPLEMDKVYKVVLPSYLVN 505
Query 592 GSDYYHTL 599
G D + +
Sbjct 506 GGDGFQMI 513
>A0A2I4HXH5 Snake venom 5'-nucleotidase [Naja atra]
Length=529
Score = 154 bits (389), Expect = 2e-43
Identities = 104/299 (35%), Positives = 152/299 (51%), Gaps = 22/299 (7%)
Query 61 LKIIHINDHHSHLDEERMEFDLNTGSTSGTYSVSRGGFARVSALFNQLAMGHGAILKLHA 120
L I+H ND H+ L++ + TG GG AR + Q+ H +L L A
Sbjct 5 LTILHTNDVHARLEQTSRDSGKCTGEDC------YGGVARRATKIRQIRASHRNVLLLDA 58
Query 121 GDATTGDLYYNLTKGKADADVMNMICFDAFTLGNHEFDNKDQGLKYFIDALDQGDCPTRT 180
GD G +++N KG+ MN + +DA LGNHEFDN GL +D L + +
Sbjct 59 GDQYQGTIWFNYYKGREVVHFMNSLRYDAMALGNHEFDN---GLNGLLDPLLKN---VKF 112
Query 181 AILSANVEFGPSSPLYQ--STRIQKSTVIETQGQKIGLVGLTIAQKTKNASQPNPDTLFK 238
ILSAN+ P P+ S I +I +K+G++G T ++T S P P F+
Sbjct 113 PILSANIR--PKGPIASNISGYILPYKIINVGSEKVGIIGYT-TKETPVLSNPGPYLEFR 169
Query 239 DELESAQQQIDLLRQAGINKIILQSHVGYEMDKYLATQLHGVDVIVGGDSHTLL--GSQN 296
DE+E Q+ D L G+NKII H G+ D +A ++ GVDV+VGG ++T L GS
Sbjct 170 DEVEELQKHADKLTTLGVNKIIALGHSGFMEDCRIAQKVKGVDVVVGGHTNTFLYTGSPP 229
Query 297 LEKVGMTPEAPYPTTLQNKDGDPVCIVQAWQYSYVVGELDITFDSQGRVKNCQGTPHIL 355
+V YP + DG V +VQA+ + +G L++TFD +G+V G P +L
Sbjct 230 SNEVA---AGNYPFMQLSDDGRQVPVVQAYAFGKYLGYLNVTFDDKGKVIKASGNPILL 285
Score = 58.9 bits (141), Expect = 3e-12
Identities = 37/129 (29%), Positives = 70/129 (54%), Gaps = 9/129 (7%)
Query 478 LSILNGGGVRTDVEQ----GPISVEKVYQVLPYNSTLVQLNMQGNEIKATLEDAVDAVIT 533
+ I+NGGG+R+ +++ G I++E++ VLP+ T L ++G+ ++ E +V
Sbjct 361 MCIVNGGGIRSPIDEQANNGIITLEELTAVLPFGGTFDLLQIKGSTLRQAFEHSVHR--H 418
Query 534 LNNTGSYPYTAGLRWSVDFNQPKGQRISNIELKDSSGE---YSLLMMDQTYRVVTLDFLA 590
TG +G++ D +Q G+R+ ++ + + Y L M++TY+V+ FLA
Sbjct 419 GQGTGELLQVSGIKVVYDLSQKPGKRVVSLNVLCTECRVPTYVPLEMEKTYKVLLPSFLA 478
Query 591 NGSDYYHTL 599
G D Y+ L
Sbjct 479 AGGDGYYML 487
>Q05927 5'-nucleotidase [Bos taurus]
Length=574
Score = 153 bits (387), Expect = 7e-43
Identities = 105/302 (35%), Positives = 161/302 (53%), Gaps = 27/302 (9%)
Query 61 LKIIHINDHHSHLDEERMEFDLNTGSTSGTYSVSR--GGFARVSALFNQLAMGHGAILKL 118
L I+H ND HS L++ + +S + SR GG AR++ +Q+ +L L
Sbjct 29 LTILHTNDVHSRLEQ-------TSEDSSKCVNASRCVGGVARLATKVHQIRRAEPHVLLL 81
Query 119 HAGDATTGDLYYNLTKGKADADVMNMICFDAFTLGNHEFDNKDQGLKYFIDALDQGDCPT 178
AGD G +++ + KG A MN + +DA LGNHEFDN +GL ID L +
Sbjct 82 DAGDQYQGTIWFTVYKGTEVAHFMNALGYDAMALGNHEFDNGVEGL---IDPLLK---EV 135
Query 179 RTAILSANVEF-GPS----SPLYQSTRIQKSTVIETQGQKIGLVGLTIAQKTKNASQPNP 233
ILSAN++ GP S LY +I + + +G+VG T +++T S P
Sbjct 136 NFPILSANIKAKGPLASKISGLYSPYKI-----LTVGDEVVGIVGYT-SKETPFLSNPGT 189
Query 234 DTLFKDELESAQQQIDLLRQAGINKIILQSHVGYEMDKYLATQLHGVDVIVGGDSHTLLG 293
+ +F+DE+ + Q ++D L+ +NKII H G+E+DK +A ++ GVDV+VGG S+T L
Sbjct 190 NLVFEDEITALQPEVDKLKTLNVNKIIALGHSGFEVDKLIAQKVKGVDVVVGGHSNTFLY 249
Query 294 SQNLEKVGMTPEAPYPTTLQNKDGDPVCIVQAWQYSYVVGELDITFDSQGRVKNCQGTPH 353
+ N + P YP + + DG V +VQA+ + +G L + FD +G V G P
Sbjct 250 TGNPPSKEV-PAGQYPFIVTSDDGRKVPVVQAYAFGKYLGYLKVEFDEKGNVVTSHGNPI 308
Query 354 IL 355
+L
Sbjct 309 LL 310
Score = 57.4 bits (137), Expect = 1e-11
Identities = 35/128 (27%), Positives = 64/128 (50%), Gaps = 8/128 (6%)
Query 478 LSILNGGGVRTDVEQ---GPISVEKVYQVLPYNSTLVQLNMQGNEIKATLEDAVDAVITL 534
+ ILNGGG+R+ +++ G I+ E + VLP+ T + ++G+ +K E +V
Sbjct 386 MCILNGGGIRSPIDERNNGTITWENLAAVLPFGGTFDLVQLKGSTLKKAFEHSVHRYGQA 445
Query 535 NNTGSYPYTAGLRWSVDFNQPKGQRISNIELKDSS---GEYSLLMMDQTYRVVTLDFLAN 591
TG + G+ D ++ G R+ +E+ + Y L MD+ Y+V+ FL +
Sbjct 446 --TGEFLQVGGIHVVYDISRNPGDRVVKLEVLCTQCRVPSYEPLRMDKVYKVILPSFLVS 503
Query 592 GSDYYHTL 599
G D + +
Sbjct 504 GGDGFQMI 511
>P21589 5'-nucleotidase [Homo sapiens]
Length=574
Score = 153 bits (387), Expect = 7e-43
Identities = 103/298 (35%), Positives = 159/298 (53%), Gaps = 19/298 (6%)
Query 61 LKIIHINDHHSHLDEERMEFDLNTGSTSGTYSVSR--GGFARVSALFNQLAMGHGAILKL 118
L I+H ND HS L++ + +S + SR GG AR+ Q+ +L L
Sbjct 29 LTILHTNDVHSRLEQ-------TSEDSSKCVNASRCMGGVARLFTKVQQIRRAEPNVLLL 81
Query 119 HAGDATTGDLYYNLTKGKADADVMNMICFDAFTLGNHEFDNKDQGLKYFIDALDQGDCPT 178
AGD G +++ + KG A MN + +DA LGNHEFDN +GL I+ L +
Sbjct 82 DAGDQYQGTIWFTVYKGAEVAHFMNALRYDAMALGNHEFDNGVEGL---IEPLLK---EA 135
Query 179 RTAILSANVEF-GPSSPLYQSTRIQKSTVIETQGQKIGLVGLTIAQKTKNASQPNPDTLF 237
+ ILSAN++ GP + + V+ + +G+VG T +++T S P + +F
Sbjct 136 KFPILSANIKAKGPLASQISGLYLPYK-VLPVGDEVVGIVGYT-SKETPFLSNPGTNLVF 193
Query 238 KDELESAQQQIDLLRQAGINKIILQSHVGYEMDKYLATQLHGVDVIVGGDSHTLLGSQNL 297
+DE+ + Q ++D L+ +NKII H G+EMDK +A ++ GVDV+VGG S+T L + N
Sbjct 194 EDEITALQPEVDKLKTLNVNKIIALGHSGFEMDKLIAQKVRGVDVVVGGHSNTFLYTGNP 253
Query 298 EKVGMTPEAPYPTTLQNKDGDPVCIVQAWQYSYVVGELDITFDSQGRVKNCQGTPHIL 355
+ P YP + + DG V +VQA+ + +G L I FD +G V + G P +L
Sbjct 254 PSKEV-PAGKYPFIVTSDDGRKVPVVQAYAFGKYLGYLKIEFDERGNVISSHGNPILL 310
Score = 63.2 bits (152), Expect = 2e-13
Identities = 37/128 (29%), Positives = 67/128 (52%), Gaps = 8/128 (6%)
Query 478 LSILNGGGVRTDVEQ---GPISVEKVYQVLPYNSTLVQLNMQGNEIKATLEDAVDAVITL 534
+ ILNGGG+R+ +++ G I+ E + VLP+ T + ++G+ +K E +V
Sbjct 386 MCILNGGGIRSPIDERNNGTITWENLAAVLPFGGTFDLVQLKGSTLKKAFEHSVHRYG-- 443
Query 535 NNTGSYPYTAGLRWSVDFNQPKGQRISNIEL---KDSSGEYSLLMMDQTYRVVTLDFLAN 591
+TG + G+ D ++ G R+ +++ K Y L MD+ Y+V+ +FLAN
Sbjct 444 QSTGEFLQVGGIHVVYDLSRKPGDRVVKLDVLCTKCRVPSYDPLKMDEVYKVILPNFLAN 503
Query 592 GSDYYHTL 599
G D + +
Sbjct 504 GGDGFQMI 511
>F8S0Z7 Snake venom 5'-nucleotidase [Crotalus adamanteus]
Length=588
Score = 150 bits (379), Expect = 9e-42
Identities = 103/306 (34%), Positives = 152/306 (50%), Gaps = 18/306 (6%)
Query 55 ASDDSSLKIIHINDHHSHLDEERMEFDLNTGSTSGTYSVSRGGFARVSALFNQLAMGHGA 114
A+ L I+H ND H+ +++ + TG GG AR + +L H
Sbjct 38 AAGSFELTILHTNDVHARVEQTSRDSGKCTGQDC------YGGVARRATKIRELRAKHRH 91
Query 115 ILKLHAGDATTGDLYYNLTKGKADADVMNMICFDAFTLGNHEFDNKDQGLKYFIDALDQG 174
+L L AGD G +++N KG+ MN + +DA LGNHEFDN GL +D L +
Sbjct 92 VLLLDAGDQYQGTVWFNFFKGREVVKFMNSLRYDAMALGNHEFDN---GLAGLLDPLLKH 148
Query 175 DCPTRTAILSANVEFGPSSPLYQSTRIQKSTVIETQGQKIGLVGLTIAQKTKNASQPNPD 234
ILSAN+ S S I +I +K+G++G T ++T S P P
Sbjct 149 ---ANFPILSANIRPKGSIASNISGYILPYKIINVGSEKVGIIGYT-TKETPVLSNPGPY 204
Query 235 TLFKDELESAQQQIDLLRQAGINKIILQSHVGYEMDKYLATQLHGVDVIVGGDSHTLL-- 292
F+DE+E Q + L G+NKII H G+ D+ +A ++ GVDV+VGG ++T L
Sbjct 205 LEFRDEVEELQNHANKLTTLGVNKIIALGHSGFSEDQRIARKVKGVDVVVGGHTNTFLYT 264
Query 293 GSQNLEKVGMTPEAPYPTTLQNKDGDPVCIVQAWQYSYVVGELDITFDSQGRVKNCQGTP 352
GS +V YP +Q+ DG V +VQA+ + +G L++ FD +G V G P
Sbjct 265 GSPPSTEVA---AGNYPFMVQSDDGRQVPVVQAYAFGKYLGYLNVIFDDKGNVIKSSGNP 321
Query 353 HILIGD 358
+L D
Sbjct 322 ILLNKD 327
Score = 55.5 bits (132), Expect = 4e-11
Identities = 35/129 (27%), Positives = 67/129 (52%), Gaps = 9/129 (7%)
Query 478 LSILNGGGVRTDVEQ----GPISVEKVYQVLPYNSTLVQLNMQGNEIKATLEDAVDAVIT 533
+ I+NGGG+R+ +++ G I++E++ VLP+ T L ++G+ +K E +V
Sbjct 400 MCIVNGGGIRSPIDERTNNGTITLEELTAVLPFGGTFDLLQIKGSALKQAFEHSVHR--H 457
Query 534 LNNTGSYPYTAGLRWSVDFNQPKGQRISNIELKDSSGE---YSLLMMDQTYRVVTLDFLA 590
G +G++ D ++ G R+ ++ + + Y L ++TY+++ FLA
Sbjct 458 GEGMGELLQVSGIKVVYDLSRKPGSRVLSLNVLCTECRVPTYVPLEKEKTYKLLLPSFLA 517
Query 591 NGSDYYHTL 599
G D YH L
Sbjct 518 AGGDGYHML 526
>B6EWW8 Snake venom 5'-nucleotidase [Gloydius brevicaudus]
Length=588
Score = 147 bits (372), Expect = 7e-41
Identities = 100/303 (33%), Positives = 152/303 (50%), Gaps = 18/303 (6%)
Query 55 ASDDSSLKIIHINDHHSHLDEERMEFDLNTGSTSGTYSVSRGGFARVSALFNQLAMGHGA 114
A+ L I+H ND H+ +++ + TG GG AR + +L H
Sbjct 38 AAGSFELTILHTNDVHARVEQTSRDSGKCTGQDC------YGGVARRATKIRELRANHSH 91
Query 115 ILKLHAGDATTGDLYYNLTKGKADADVMNMICFDAFTLGNHEFDNKDQGLKYFIDALDQG 174
+L L AGD G ++++ KG+ MN + +DA LGNHEFDN GL +D L +
Sbjct 92 VLLLDAGDQYQGTIWFSFFKGREVVKFMNSLGYDAMALGNHEFDN---GLAGLLDPLLKH 148
Query 175 DCPTRTAILSANVEFGPSSPLYQSTRIQKSTVIETQGQKIGLVGLTIAQKTKNASQPNPD 234
ILSAN+ S S I +I +K+G++G T ++T S P P
Sbjct 149 ---ANFPILSANIRPKGSIASNISGYILPYKIINVGSEKVGIIGYT-TKETPVLSNPGPY 204
Query 235 TLFKDELESAQQQIDLLRQAGINKIILQSHVGYEMDKYLATQLHGVDVIVGGDSHTLL-- 292
F+DE+E Q+ + L G+NKII H G+ D+ +A ++ GVDV+VGG ++T L
Sbjct 205 LEFRDEVEELQKHANKLTTLGVNKIIALGHSGFFEDQRIARKVKGVDVVVGGHTNTFLYT 264
Query 293 GSQNLEKVGMTPEAPYPTTLQNKDGDPVCIVQAWQYSYVVGELDITFDSQGRVKNCQGTP 352
GS +V YP +++ DG V +VQA+ + +G L++ FD +G V G P
Sbjct 265 GSPPSTEVA---AGNYPFMVKSDDGRQVPVVQAYAFGKYLGYLNVIFDDKGNVIKSSGNP 321
Query 353 HIL 355
+L
Sbjct 322 ILL 324
Score = 54.7 bits (130), Expect = 7e-11
Identities = 35/129 (27%), Positives = 66/129 (51%), Gaps = 9/129 (7%)
Query 478 LSILNGGGVRTDVEQ----GPISVEKVYQVLPYNSTLVQLNMQGNEIKATLEDAVDAVIT 533
+ I+NGGG+R+ +++ G I++E++ VLP+ T L ++G +K E +V
Sbjct 400 MCIVNGGGIRSPIDERANNGTITLEELTAVLPFGGTFDLLQIKGCALKQAFEHSVHR--H 457
Query 534 LNNTGSYPYTAGLRWSVDFNQPKGQRISNIELKDSSGE---YSLLMMDQTYRVVTLDFLA 590
G +G++ D ++ G R+ ++ + + Y L ++TY+++ FLA
Sbjct 458 GQGMGELLQVSGIKVVYDLSRKPGSRVVSLNVLCTECRVPTYVPLEKEKTYKLLLPSFLA 517
Query 591 NGSDYYHTL 599
G D YH L
Sbjct 518 GGGDGYHML 526
Lambda K H a alpha
0.317 0.134 0.385 0.792 4.96
Gapped
Lambda K H a alpha sigma
0.267 0.0410 0.140 1.90 42.6 43.6
Effective search space used: 3961095
Database: 0378d9b96e337ad3dc978764ba8e38bd.SwissProt.fasta
Posted date: May 9, 2024 6:10 PM
Number of letters in database: 7,240
Number of sequences in database: 11
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Neighboring words threshold: 11
Window for multiple hits: 40
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Data ...
