BLASTP 2.12.0+
Reference: Stephen F. Altschul, Thomas L. Madden, Alejandro A.
Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J.
Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of
protein database search programs", Nucleic Acids Res. 25:3389-3402.
Reference for composition-based statistics: Alejandro A. Schaffer,
L. Aravind, Thomas L. Madden, Sergei Shavirin, John L. Spouge, Yuri
I. Wolf, Eugene V. Koonin, and Stephen F. Altschul (2001),
"Improving the accuracy of PSI-BLAST protein database searches with
composition-based statistics and other refinements", Nucleic Acids
Res. 29:2994-3005.
Database: 8aee90b20d0f360036bdd9b7993ce82e.SwissProt.fasta
20 sequences; 18,942 total letters
Query= ACIAD0022
Length=946
Score E
Sequences producing significant alignments: (Bits) Value
Q6FG02 Isoleucine--tRNA ligase [Acinetobacter baylyi (strain ATCC... 1930 0.0
Q4FUS5 Isoleucine--tRNA ligase [Psychrobacter arcticus (strain DS... 1182 0.0
Q0VSE1 Isoleucine--tRNA ligase [Alcanivorax borkumensis (strain A... 1122 0.0
Q3J8W1 Isoleucine--tRNA ligase [Nitrosococcus oceani (strain ATCC... 1108 0.0
Q605M7 Isoleucine--tRNA ligase [Methylococcus capsulatus (strain ... 1104 0.0
A4Y4A4 Isoleucine--tRNA ligase [Shewanella putrefaciens (strain C... 1102 0.0
A8FSI2 Isoleucine--tRNA ligase [Shewanella sediminis (strain HAW-... 1102 0.0
A1RMM6 Isoleucine--tRNA ligase [Shewanella sp. (strain W3-18-1)] 1101 0.0
A3D1G5 Isoleucine--tRNA ligase [Shewanella baltica (strain OS155 ... 1100 0.0
A8H1H3 Isoleucine--tRNA ligase [Shewanella pealeana (strain ATCC ... 1100 0.0
P00956 Isoleucine--tRNA ligase [Escherichia coli (strain K12)] 1070 0.0
P18330 Isoleucine--tRNA ligase 1 [Pseudomonas fluorescens] 989 0.0
P46213 Isoleucine--tRNA ligase [Thermotoga maritima (strain ATCC ... 741 0.0
Q9XDB4 Isoleucine--tRNA ligase [Fervidobacterium pennivorans (str... 730 0.0
P41972 Isoleucine--tRNA ligase [Staphylococcus aureus] 723 0.0
Q846V6 Isoleucine--tRNA ligase [Staphylococcus epidermidis] 686 0.0
P41257 Isoleucine--tRNA ligase [Campylobacter jejuni subsp. jejun... 620 0.0
Q9NSE4 Isoleucine--tRNA ligase, mitochondrial [Homo sapiens] 542 1e-180
P46214 Isoleucine--tRNA ligase [Pyrococcus furiosus (strain ATCC ... 432 5e-138
P26499 Isoleucine--tRNA ligase [Methanothermobacter marburgensis ... 429 5e-137
>Q6FG02 Isoleucine--tRNA ligase [Acinetobacter baylyi (strain
ATCC 33305 / BD413 / ADP1)]
Length=945
Score = 1930 bits (4999), Expect = 0.0
Identities = 945/945 (100%), Positives = 945/945 (100%), Gaps = 0/945 (0%)
Query 1 MSDKQTPENAVDYKATLNLPGTEFAMKANLAVREVKWLEEWYADNIYQKIRASRIGKKKY 60
MSDKQTPENAVDYKATLNLPGTEFAMKANLAVREVKWLEEWYADNIYQKIRASRIGKKKY
Sbjct 1 MSDKQTPENAVDYKATLNLPGTEFAMKANLAVREVKWLEEWYADNIYQKIRASRIGKKKY 60
Query 61 VLHDGPPYANGQIHLGHAVNKVLKDIIVKSRVMDGFDAPYVPGWDCHGLPIELKVEEKVG 120
VLHDGPPYANGQIHLGHAVNKVLKDIIVKSRVMDGFDAPYVPGWDCHGLPIELKVEEKVG
Sbjct 61 VLHDGPPYANGQIHLGHAVNKVLKDIIVKSRVMDGFDAPYVPGWDCHGLPIELKVEEKVG 120
Query 121 KVGVKVDASTFRKACREYALSQVDLQRKDFIRMGVFGDWQDPYLTMNFKQEADIVRSLGE 180
KVGVKVDASTFRKACREYALSQVDLQRKDFIRMGVFGDWQDPYLTMNFKQEADIVRSLGE
Sbjct 121 KVGVKVDASTFRKACREYALSQVDLQRKDFIRMGVFGDWQDPYLTMNFKQEADIVRSLGE 180
Query 181 IQKAGHIEPGLKPVNWCIDCGSALAEAEVEYEDKKSDAIDVGFGVVDLNDLSARLNVEVQ 240
IQKAGHIEPGLKPVNWCIDCGSALAEAEVEYEDKKSDAIDVGFGVVDLNDLSARLNVEVQ
Sbjct 181 IQKAGHIEPGLKPVNWCIDCGSALAEAEVEYEDKKSDAIDVGFGVVDLNDLSARLNVEVQ 240
Query 241 DPTDIVIWTTTPWTLPANQAVALHAEIDYQLVQVQSDRGTQNFILAKDLVESAIARYKLE 300
DPTDIVIWTTTPWTLPANQAVALHAEIDYQLVQVQSDRGTQNFILAKDLVESAIARYKLE
Sbjct 241 DPTDIVIWTTTPWTLPANQAVALHAEIDYQLVQVQSDRGTQNFILAKDLVESAIARYKLE 300
Query 301 NPVVLADFKGAVLELLQLQHPLLADRQVPVILGEHVIATSGTGAVHTAPGHGTDDYKVGL 360
NPVVLADFKGAVLELLQLQHPLLADRQVPVILGEHVIATSGTGAVHTAPGHGTDDYKVGL
Sbjct 301 NPVVLADFKGAVLELLQLQHPLLADRQVPVILGEHVIATSGTGAVHTAPGHGTDDYKVGL 360
Query 361 IYNLKVDNPVGGNGVYLPTAPIFSGEHIYKANPQIIEALGATGRLWAHQPIVHSYPHCWR 420
IYNLKVDNPVGGNGVYLPTAPIFSGEHIYKANPQIIEALGATGRLWAHQPIVHSYPHCWR
Sbjct 361 IYNLKVDNPVGGNGVYLPTAPIFSGEHIYKANPQIIEALGATGRLWAHQPIVHSYPHCWR 420
Query 421 HKTPIIFRATPQWFISMDAKGLRECALNAIENDISFVPDWGKNRIESMIEGRPDWCISRQ 480
HKTPIIFRATPQWFISMDAKGLRECALNAIENDISFVPDWGKNRIESMIEGRPDWCISRQ
Sbjct 421 HKTPIIFRATPQWFISMDAKGLRECALNAIENDISFVPDWGKNRIESMIEGRPDWCISRQ 480
Query 481 RTWGVPIPFFVHKDTNELHPRTPELIEEVAQLIEHEGIDAWFNREAKDFIGADAEHYNAV 540
RTWGVPIPFFVHKDTNELHPRTPELIEEVAQLIEHEGIDAWFNREAKDFIGADAEHYNAV
Sbjct 481 RTWGVPIPFFVHKDTNELHPRTPELIEEVAQLIEHEGIDAWFNREAKDFIGADAEHYNAV 540
Query 541 RDTLDVWFDSGTTHYAVLRQREELTDPADLYLEGSDQHRGWFQSSLLTSIAINERAPYKG 600
RDTLDVWFDSGTTHYAVLRQREELTDPADLYLEGSDQHRGWFQSSLLTSIAINERAPYKG
Sbjct 541 RDTLDVWFDSGTTHYAVLRQREELTDPADLYLEGSDQHRGWFQSSLLTSIAINERAPYKG 600
Query 601 LLTHGFVVDEKGRKMSKSLGNIITPQDIIKDMGADGLRFWIASSDYRYEMTAGKEIFSRA 660
LLTHGFVVDEKGRKMSKSLGNIITPQDIIKDMGADGLRFWIASSDYRYEMTAGKEIFSRA
Sbjct 601 LLTHGFVVDEKGRKMSKSLGNIITPQDIIKDMGADGLRFWIASSDYRYEMTAGKEIFSRA 660
Query 661 SDGYRRIRNTLRFLLANLNGFTPSTDALPVDQLIALDQYILQRAAEVQKTVQQAYEDMNF 720
SDGYRRIRNTLRFLLANLNGFTPSTDALPVDQLIALDQYILQRAAEVQKTVQQAYEDMNF
Sbjct 661 SDGYRRIRNTLRFLLANLNGFTPSTDALPVDQLIALDQYILQRAAEVQKTVQQAYEDMNF 720
Query 721 HIVCSALTNFCINDLGGFYLDIIKDRQYTTKADSAARHSAQTALYHLVQAFVRWMSPILS 780
HIVCSALTNFCINDLGGFYLDIIKDRQYTTKADSAARHSAQTALYHLVQAFVRWMSPILS
Sbjct 721 HIVCSALTNFCINDLGGFYLDIIKDRQYTTKADSAARHSAQTALYHLVQAFVRWMSPILS 780
Query 781 FTAQEAWPLIPEQTEQYVFTTEWYDIPVASTANLISEADWQTLISVKSAVNKQIEAARNA 840
FTAQEAWPLIPEQTEQYVFTTEWYDIPVASTANLISEADWQTLISVKSAVNKQIEAARNA
Sbjct 781 FTAQEAWPLIPEQTEQYVFTTEWYDIPVASTANLISEADWQTLISVKSAVNKQIEAARNA 840
Query 841 KLVGSNLSAKVEIWAKDELQSVLNQLGDELRFVLITSQVNVYPYAEQGESTEMDGLRVQI 900
KLVGSNLSAKVEIWAKDELQSVLNQLGDELRFVLITSQVNVYPYAEQGESTEMDGLRVQI
Sbjct 841 KLVGSNLSAKVEIWAKDELQSVLNQLGDELRFVLITSQVNVYPYAEQGESTEMDGLRVQI 900
Query 901 SAAEGEKCVRCWHVLPDVNTHADHPGLCGRCIINVTGSGEVRKYA 945
SAAEGEKCVRCWHVLPDVNTHADHPGLCGRCIINVTGSGEVRKYA
Sbjct 901 SAAEGEKCVRCWHVLPDVNTHADHPGLCGRCIINVTGSGEVRKYA 945
>Q4FUS5 Isoleucine--tRNA ligase [Psychrobacter arcticus (strain
DSM 17307 / VKM B-2377 / 273-4)]
Length=941
Score = 1182 bits (3057), Expect = 0.0
Identities = 583/946 (62%), Positives = 699/946 (74%), Gaps = 21/946 (2%)
Query 12 DYKATLNLPGTEFAMKANLAVREVKWLEEWYADNIYQKIRASRIGKKKYVLHDGPPYANG 71
DYK TLNL T FAM+ANLA RE WL W AD++Y KIR +R G KY+LHDGPPYANG
Sbjct 5 DYKDTLNLADTPFAMRANLAKREPDWLAAWEADDVYGKIRQARAGATKYILHDGPPYANG 64
Query 72 QIHLGHAVNKVLKDIIVKSRVMDGFDAPYVPGWDCHGLPIELKVEEKVGKVGVKVDASTF 131
QIHLGHAVNKVLKDIIVKS+ + GFDAPYVPGWDCHGLPIE KVE K GKVG KV A+ F
Sbjct 65 QIHLGHAVNKVLKDIIVKSKTLSGFDAPYVPGWDCHGLPIEQKVEAKHGKVGQKVSATEF 124
Query 132 RKACREYALSQVDLQRKDFIRMGVFGDWQDPYLTMNFKQEADIVRSLGEIQKAGHIEPGL 191
R CREYA +Q++LQ+ DF R+GVFGDW +PYLTMNF QEA+IVR+L +I GH+ G+
Sbjct 125 RGLCREYARTQIELQKADFKRLGVFGDWDNPYLTMNFHQEANIVRALAKIYDNGHVTRGM 184
Query 192 KPVNWCIDCGSALAEAEVEYEDKKSDAIDVGFGVVDLNDLSARLNVEVQDPTDIVIWTTT 251
KPVNWC+DC SALAEAEVEY+DK SDAI V F +VD ++A E+ VIWTTT
Sbjct 185 KPVNWCLDCSSALAEAEVEYQDKVSDAIYVSFDIVDSGKVAAL--AEIDGNIAAVIWTTT 242
Query 252 PWTLPANQAVALHAEIDYQLVQVQSDRGTQNFILAKDLVESAIARYKLENPVVLADFKGA 311
PWTLPANQA+ALH+E +Y +V ++ N +LA DLVESA++ +KLEN VLA G
Sbjct 243 PWTLPANQAIALHSEHNYSVVATENG----NLLLATDLVESALSEFKLENKGVLATVLGR 298
Query 312 VLELLQLQHPLLADRQVPVILGEHVIATSGTGAVHTAPGHGTDDYKVGLIYNLKVDNPVG 371
LE L QHPL+ RQVP+ILG+HV SGTG VHTAPGHG DDY VGL YNL V+NPV
Sbjct 299 ELEGLHAQHPLIEARQVPLILGDHVTTDSGTGLVHTAPGHGLDDYIVGLKYNLPVENPVS 358
Query 372 GNGVYLPTAPIFSGEHIYKANPQIIEALGATGRLWAHQPIVHSYPHCWRHKTPIIFRATP 431
G GVYL +A +F+GEHIYKANPQII AL G L H I HSYPHCWRHK+PIIFRATP
Sbjct 359 GTGVYLESAAVFAGEHIYKANPQIIAALHENGHLIRHTKIEHSYPHCWRHKSPIIFRATP 418
Query 432 QWFISMDAKGLRECALNAIENDISFVPDWGKNRIESMIEGRPDWCISRQRTWGVPIPFFV 491
QWFISM+ KGLRE AL I + + P WG+NRIESM+ GRPDWCISRQRTWGVPI FF
Sbjct 419 QWFISMETKGLRERALADIPT-VQWTPAWGQNRIESMMTGRPDWCISRQRTWGVPITFFT 477
Query 492 HKDTNELHPRTPELIEEVAQLIEHEGIDAWFNREAKDFIGADAEHYNAVRDTLDVWFDSG 551
HK+T ELHP T EL+E AQ I G++AWF+ +DF+GA+A Y+ DTLDVWFDSG
Sbjct 478 HKETGELHPNTLELMETAAQRIHEGGVEAWFDASCEDFLGAEAADYDKATDTLDVWFDSG 537
Query 552 TTHYAVLRQREELTDPADLYLEGSDQHRGWFQSSLLTSIAINERAPYKGLLTHGFVVDEK 611
TTH+AVL QR+ELT+PAD+YLEGSDQHRGWFQ+SLLTS A+ ER P+K +LTHGFVVDE
Sbjct 538 TTHFAVLDQRDELTNPADMYLEGSDQHRGWFQTSLLTSEAMYERPPFKQVLTHGFVVDEN 597
Query 612 GRKMSKSLGNIITPQDIIKDMGADGLRFWIASSDYRYEMTAGKEIFSRASDGYRRIRNTL 671
GRKMSKSLGNIITPQ+ I GAD LR WIASSDYRYEM+AGK +F + D YRRIRNTL
Sbjct 598 GRKMSKSLGNIITPQEEINKTGADMLRLWIASSDYRYEMSAGKTVFKGSIDMYRRIRNTL 657
Query 672 RFLLANLNGFTPSTDALPVDQLIALDQYILQRAAEVQKTVQQAYEDMNFHIVCSALTNFC 731
RFLLAN + F P+T+++ +++L++LD++I++RA VQ + AY+ M+FH V +T FC
Sbjct 658 RFLLANTDDFDPATNSVDINELVSLDKFIIERAQTVQAQIISAYDAMDFHQVTQHITAFC 717
Query 732 INDLGGFYLDIIKDRQYTTKADSAARHSAQTALYHLVQAFVRWMSPILSFTAQEAWPLIP 791
DLG FYLDIIKDRQYTT+ D R SAQTA+YH+VQA +RW++PILSFTAQEAW ++
Sbjct 718 SQDLGSFYLDIIKDRQYTTQTDGQPRRSAQTAIYHIVQALIRWITPILSFTAQEAWEVL- 776
Query 792 EQTEQYVFTTEWYDIPVASTANLISEADWQTLISVKSAVNKQIEAARNAKLVGSNLSAKV 851
+ YVFT EWY P + IS DWQ ++ K VNK IE AR K++ +NLSA V
Sbjct 777 HGADSYVFTEEWYTFP-EFELSAISNDDWQRIMLAKDMVNKHIETARGEKIINANLSADV 835
Query 852 EIWAKDELQSVLNQLGDELRFVLITSQVNVYPYA------------EQGESTEMDGLRVQ 899
++A + L +LG+ELRFVLITS + P + ST + L V+
Sbjct 836 NLYADGAMHESLAKLGEELRFVLITSNATLKPLSTVPAHSASTDEQTDSNSTGVVDLVVE 895
Query 900 ISAAEGEKCVRCWHVLPDVNTHADHPGLCGRCIINVTGSGEVRKYA 945
+ AA G KCVRCWH+ D+ T + HP LC RC NV+G GEVR YA
Sbjct 896 VHAATGTKCVRCWHIRDDIGTDSTHPELCARCATNVSGDGEVRHYA 941
>Q0VSE1 Isoleucine--tRNA ligase [Alcanivorax borkumensis (strain
ATCC 700651 / DSM 11573 / NCIMB 13689 / SK2)]
Length=937
Score = 1122 bits (2903), Expect = 0.0
Identities = 552/938 (59%), Positives = 681/938 (73%), Gaps = 7/938 (1%)
Query 12 DYKATLNLPGTEFAMKANLAVREVKWLEEWYADNIYQKIRASRIGKKKYVLHDGPPYANG 71
DYKATLNLP T F MKA L+ RE L+EW +YQKIR + G+ K++LHDGPPYANG
Sbjct 3 DYKATLNLPQTGFPMKAGLSQREPARLKEWQQKQLYQKIREAFAGRPKFILHDGPPYANG 62
Query 72 QIHLGHAVNKVLKDIIVKSRVMDGFDAPYVPGWDCHGLPIELKVEEKVGKVGVKVDASTF 131
IH+GHAVNK+LKD+IVKSR + GFDAPYVPGWDCHGLPIEL VE+KVGK G KVDA TF
Sbjct 63 DIHIGHAVNKILKDMIVKSRTLAGFDAPYVPGWDCHGLPIELMVEKKVGKAGHKVDAGTF 122
Query 132 RKACREYALSQVDLQRKDFIRMGVFGDWQDPYLTMNFKQEADIVRSLGEIQKAGHIEPGL 191
RK CREYA QV Q+ DF+R+GV GDW +PYLTM+F EA+I+RSLG+I GH++ G
Sbjct 123 RKKCREYASKQVAGQKSDFMRLGVLGDWDNPYLTMDFTFEANIIRSLGKIVDNGHLQQGF 182
Query 192 KPVNWCIDCGSALAEAEVEYEDKKSDAIDVGFGVVDLNDLSARLNVEVQDPTDIVIWTTT 251
KPV+WC+DCGSALAEAEVEYEDK S AIDV F VVD+ D AR +E P +VIWTTT
Sbjct 183 KPVHWCLDCGSALAEAEVEYEDKISPAIDVAFPVVDVADFVARSGIEASAPA-LVIWTTT 241
Query 252 PWTLPANQAVALHAEIDYQLVQVQSDRGTQNFILAKDLVESAIARYKLENPVVLADFKGA 311
PWTLPAN+AVA+H E+DY L+ + + ++A+ L + + R+ LEN A G+
Sbjct 242 PWTLPANRAVAVHPELDYVLLSGELSGVARELLVAEALADDLVTRWGLENVTRSAAVAGS 301
Query 312 VLELLQLQHPLLADRQVPVILGEHVIATSGTGAVHTAPGHGTDDYKVGLIYNLKVDNPVG 371
LE+L LQHP L + QVPV+ GEHV +GTG VHTAPGHG DD+ VG Y+L +PV
Sbjct 302 KLEMLALQHPFL-EAQVPVVFGEHVTTDAGTGLVHTAPGHGVDDFMVGKQYDLDPISPVL 360
Query 372 GNGVYLPTAPIFSGEHIYKANPQIIEALGATGRLWAHQPIVHSYPHCWRHKTPIIFRATP 431
NG++ P+ G H+ KAN +IEAL +G L I HSYPHCWRHKTP+IFRAT
Sbjct 361 DNGLFREDLPVVGGLHVSKANEPVIEALKDSGNLVKLAKIEHSYPHCWRHKTPLIFRATA 420
Query 432 QWFISMDAKGLRECALNAIENDISFVPDWGKNRIESMIEGRPDWCISRQRTWGVPIPFFV 491
QWF+SMD GL A I+ + ++P+WGK RIE M+ RPDWCISRQRTWGVPI FV
Sbjct 421 QWFVSMDQAGLLPRARQEIDK-VQWLPEWGKARIEGMLTDRPDWCISRQRTWGVPIALFV 479
Query 492 HKDTNELHPRTPELIEEVAQLIEHEGIDAWFNREAKDFIGADAEHYNAVRDTLDVWFDSG 551
+K+T+ELHP+TP LIE+VAQ +E G+DAWF+ + + +G +A+ Y+ V DTLDVWFDSG
Sbjct 480 NKETSELHPQTPALIEQVAQRVEKAGVDAWFDLDPAELLGDEADQYSKVTDTLDVWFDSG 539
Query 552 TTHYAVLRQREELTDPADLYLEGSDQHRGWFQSSLLTSIAINERAPYKGLLTHGFVVDEK 611
THY VL QRE+L PADLYLEGSDQHRGWFQSSLLTS+AI + APY +LTHGF VDE
Sbjct 540 VTHYCVLDQREQLRAPADLYLEGSDQHRGWFQSSLLTSLAIRDAAPYSTVLTHGFTVDEH 599
Query 612 GRKMSKSLGNIITPQDIIKDMGADGLRFWIASSDYRYEMTAGKEIFSRASDGYRRIRNTL 671
GRKMSKS+GN+I PQ++ D+GAD LR W+ ++DYR EM+ K+I + D YRRIRNT
Sbjct 600 GRKMSKSVGNVIAPQEVWNDLGADILRLWVCATDYRGEMSVSKDILKQMGDSYRRIRNTS 659
Query 672 RFLLANLNGFTPSTDALPVDQLIALDQYILQRAAEVQKTVQQAYEDMNFHIVCSALTNFC 731
RFLL+NL+GF P+TDAL +Q++ALD+YI+ RA +VQ +Q Y+ +FH V L NFC
Sbjct 660 RFLLSNLSGFEPATDALQPEQMLALDRYIVDRALQVQAEIQDLYDGYHFHQVYQKLHNFC 719
Query 732 INDLGGFYLDIIKDRQYTTKADSAARHSAQTALYHLVQAFVRWMSPILSFTAQEAWPLIP 791
DLGGFYLDIIKDRQYTT+ADS AR S QTALYH+ QA VRWM+P+LSFTA+E + +P
Sbjct 720 ALDLGGFYLDIIKDRQYTTQADSVARRSCQTALYHIAQALVRWMAPVLSFTAEEIYENLP 779
Query 792 EQTEQYVFTTEWYDIPVASTANL-ISEADWQTLISVKSAVNKQIEAARNAKLVGSNLSAK 850
+ VF EWYD A N + A W + K AVNK IE AR AKL+ +LSA+
Sbjct 780 GERLDSVFLAEWYDGLFALADNADMGRAFWDKVQDAKQAVNKAIEGARAAKLIKGSLSAE 839
Query 851 VEIWAKDELQSVLNQLGDELRFVLITSQVNVYPYAE---QGESTEMDGLRVQISAAEGEK 907
V ++ E ++L +LGDELRFV ITS + P AE + E T + GL+VQ+ A++ K
Sbjct 840 VVLFVDAEQNALLQRLGDELRFVTITSAAVLKPLAEAPAELEDTSVAGLKVQVLASDHAK 899
Query 908 CVRCWHVLPDVNTHADHPGLCGRCIINVTGSGEVRKYA 945
C RCWH PDV +HA+HP LCGRCI NV G GEVR YA
Sbjct 900 CARCWHHQPDVGSHAEHPELCGRCITNVEGDGEVRHYA 937
>Q3J8W1 Isoleucine--tRNA ligase [Nitrosococcus oceani (strain
ATCC 19707 / BCRC 17464 / JCM 30415 / NCIMB 11848 / C-107)]
Length=940
Score = 1108 bits (2866), Expect = 0.0
Identities = 532/939 (57%), Positives = 673/939 (72%), Gaps = 8/939 (1%)
Query 13 YKATLNLPGTEFAMKANLAVREVKWLEEWYADNIYQKIRASRIGKKKYVLHDGPPYANGQ 72
YK TLNLP T F MKANLA RE + L+ W A ++Y K+R + G+ +++LHDGPPYANG
Sbjct 4 YKETLNLPKTAFPMKANLAQREPQALKRWQAMDLYGKLRNAARGRPRFILHDGPPYANGA 63
Query 73 IHLGHAVNKVLKDIIVKSRVMDGFDAPYVPGWDCHGLPIELKVEEKVGKVGVKVDASTFR 132
IH+GHAVNK+LKDIIVKS+ + GFDAPYVPGWDCHGLPIEL VE+KVGK G K+D ++FR
Sbjct 64 IHIGHAVNKILKDIIVKSKSLSGFDAPYVPGWDCHGLPIELNVEKKVGKPGRKIDVASFR 123
Query 133 KACREYALSQVDLQRKDFIRMGVFGDWQDPYLTMNFKQEADIVRSLGEIQKAGHIEPGLK 192
+ACR+YA QV+ QR+DF R+GV GDW PYLTM+++ EAD++R+LG+I + GH+ G+K
Sbjct 124 RACRDYARKQVNAQREDFERLGVLGDWCHPYLTMDYQFEADVIRTLGKIIEKGHLHKGVK 183
Query 193 PVNWCIDCGSALAEAEVEYEDKKSDAIDVGFGVVDLNDLSARLNVEVQD--PTDIVIWTT 250
PV+WC+DCGSALAEAEVEY++K S AIDV F VV+ +L AR E+ P +VIWTT
Sbjct 184 PVHWCVDCGSALAEAEVEYQEKTSPAIDVRFPVVEEVELLARCKAEIPGAGPMSVVIWTT 243
Query 251 TPWTLPANQAVALHAEIDYQLVQVQSDRGTQNFILAKDLVESAIARYKLENPVVLADFKG 310
TPWTLPANQAVALH + Y LV+ + +G + +LA+ L +ARY E+ V+LA +G
Sbjct 244 TPWTLPANQAVALHPALKYVLVECSAGQGRERLLLAEGLYREVLARYSAESAVILATCQG 303
Query 311 AVLELLQLQHPLLADRQVPVILGEHVIATSGTGAVHTAPGHGTDDYKVGLIYNLKVDNPV 370
LE L+LQHP +R VP+ILGEHV +GTGAVHTAPGHG DDY VG Y L +DNPV
Sbjct 304 DELEGLKLQHPFY-ERTVPIILGEHVNLEAGTGAVHTAPGHGQDDYVVGNRYQLSIDNPV 362
Query 371 GGNGVYLPTAPIFSGEHIYKANPQIIEALGATGRLWAHQPIVHSYPHCWRHKTPIIFRAT 430
GGNG +LP P+F+GE ++KAN II+ L G L Q + HSYPHCWRHKTPIIFRAT
Sbjct 363 GGNGCFLPETPLFAGEPVFKANDHIIQVLKERGNLLREQSLQHSYPHCWRHKTPIIFRAT 422
Query 431 PQWFISMDAKGLRECALNAIENDISFVPDWGKNRIESMIEGRPDWCISRQRTWGVPIPFF 490
PQWFI+M+ +GLR AL I+ ++P WG+ RIE M+E RPDWCISRQR WG PIP F
Sbjct 423 PQWFINMEREGLRTAALAEIKKT-RWLPGWGQQRIEGMVENRPDWCISRQRAWGTPIPLF 481
Query 491 VHKDTNELHPRTPELIEEVAQLIEHEGIDAWFNREAKDFIGADAEHYNAVRDTLDVWFDS 550
VH T ELHP TP L+EEVA+ +E +GI+AWF E K+ +G A Y V DTLDVWFDS
Sbjct 482 VHCQTGELHPDTPRLMEEVARRVEEKGIEAWFELEPKELLGNQAPAYEKVGDTLDVWFDS 541
Query 551 GTTHYAVLRQREELTDPADLYLEGSDQHRGWFQSSLLTSIAINERAPYKGLLTHGFVVDE 610
G TH VL REEL PADLYLEGSDQHRGWFQSSLLTS+AI APY+ +LTHGF VD
Sbjct 542 GVTHTCVLETREELGVPADLYLEGSDQHRGWFQSSLLTSVAIRGTAPYRMVLTHGFTVDA 601
Query 611 KGRKMSKSLGNIITPQDIIKDMGADGLRFWIASSDYRYEMTAGKEIFSRASDGYRRIRNT 670
KG+KMSKS GN++ PQ ++ +GAD LR W+A++DYR EM EI R +D YRR+RNT
Sbjct 602 KGKKMSKSQGNVVAPQQVMGSLGADILRLWVAATDYRGEMNVSDEILKRIADSYRRMRNT 661
Query 671 LRFLLANLNGFTPSTDALPVDQLIALDQYILQRAAEVQKTVQQAYEDMNFHIVCSALTNF 730
R+LLANLNGF P+ +P ++ALD++ L RA+ +Q + QAYED NFH++ + NF
Sbjct 662 ARYLLANLNGFDPTIHGVPAKDMLALDRWALDRASLLQGEIVQAYEDYNFHLIYQRVHNF 721
Query 731 CINDLGGFYLDIIKDRQYTTKADSAARHSAQTALYHLVQAFVRWMSPILSFTAQEAWPLI 790
C D+G YLDIIKDRQYTT+ADS AR SAQTA+YH+ +A VRW++P+LSFTA E W +
Sbjct 722 CAVDMGAIYLDIIKDRQYTTQADSRARRSAQTAMYHIAEALVRWLAPVLSFTADEIWQYL 781
Query 791 PEQTEQYVFTTEWY-DIPVASTANLISEADWQTLISVKSAVNKQIEAARNAKLVGSNLSA 849
P + + VF T WY D+P A W +++ + A+ K +E R +GS+L A
Sbjct 782 PGERGESVFLTTWYEDLPSLGEEAPWGRAFWDVILAAREAIAKVLEGVRVEGRIGSSLDA 841
Query 850 KVEIWAKDELQSVLNQLGDELRFVLITSQVNVYPYAE---QGESTEMDGLRVQISAAEGE 906
+V+++ ++ L L +LGDELRFVLITS VYP + + TEM GL + +
Sbjct 842 EVDLYVEESLYQALRKLGDELRFVLITSYARVYPAQKRPVEALETEMPGLWTVVIPSHYP 901
Query 907 KCVRCWHVLPDVNTHADHPGLCGRCIINVTGSGEVRKYA 945
KCVRCWH +V +H DHP LC RC+ N G GE R +A
Sbjct 902 KCVRCWHHREEVGSHEDHPELCSRCVENTEGGGEQRAFA 940
>Q605M7 Isoleucine--tRNA ligase [Methylococcus capsulatus (strain
ATCC 33009 / NCIMB 11132 / Bath)]
Length=939
Score = 1104 bits (2855), Expect = 0.0
Identities = 534/942 (57%), Positives = 681/942 (72%), Gaps = 12/942 (1%)
Query 11 VDYKATLNLPGTEFAMKANLAVREVKWLEEWYADNIYQKIRASRIGKKKYVLHDGPPYAN 70
+DYK+TLNLP T F MKANLA RE + +E W ++Y+K+R+ R G+ K++LHDGPPYAN
Sbjct 1 MDYKSTLNLPQTPFPMKANLAQREPEQIERWRTLDLYRKVRSRRAGRDKFILHDGPPYAN 60
Query 71 GQIHLGHAVNKVLKDIIVKSRVMDGFDAPYVPGWDCHGLPIELKVEEKVGKVGVKVDAST 130
G+IH+GHAVNK+LKD IVKSR + GFDAPYVPGWDCHGLPIEL VE+K+GK G KV +
Sbjct 61 GEIHIGHAVNKILKDFIVKSRTLSGFDAPYVPGWDCHGLPIELMVEKKIGKAGHKVSPAE 120
Query 131 FRKACREYALSQVDLQRKDFIRMGVFGDWQDPYLTMNFKQEADIVRSLGEIQKAGHIEPG 190
FRKACREYA +QVDLQR++FIR+GV GDW++PYLTM+F+ EADIVR+LG I GH+ G
Sbjct 121 FRKACREYAAAQVDLQRREFIRLGVLGDWENPYLTMDFRFEADIVRALGRIAARGHLAKG 180
Query 191 LKPVNWCIDCGSALAEAEVEYEDKKSDAIDVGFGVVDLNDLSARLNVEV----QDPTDIV 246
KPV+WC+DCGSALAEAEVEYE+K S AIDV F VVD L AR + + P +V
Sbjct 181 AKPVHWCLDCGSALAEAEVEYENKHSPAIDVRFAVVDEFGLMARFHTADGALGEGPLSVV 240
Query 247 IWTTTPWTLPANQAVALHAEIDYQLVQVQSDRGTQNFILAKDLVESAIARYKLENPVVLA 306
IWTTTPWTLPANQAVAL+ E+DY +VQ + + +LA L++ + R E V+
Sbjct 241 IWTTTPWTLPANQAVALNPELDYVVVQRTDIK--ERLVLADALMKDVMLRCGAEGYRVIG 298
Query 307 DFKGAVLELLQLQHPLLADRQVPVILGEHVIATSGTGAVHTAPGHGTDDYKVGLIYNLKV 366
KGA LE +QL+HP DR VPVILG+HV +GTGAVHTAPGHG +DY VG Y L V
Sbjct 299 YCKGAALEGVQLRHPFY-DRIVPVILGDHVTLDAGTGAVHTAPGHGQEDYAVGQRYGLAV 357
Query 367 DNPVGGNGVYLPTAPIFSGEHIYKANPQIIEALGATGRLWAHQPIVHSYPHCWRHKTPII 426
DNPVGG+G +LP +F+GEH+ AN +IE L G L I HSYPHCWRHKTP+I
Sbjct 358 DNPVGGDGRFLPNTELFAGEHVLSANDHVIEVLKERGALLHEARIEHSYPHCWRHKTPVI 417
Query 427 FRATPQWFISMDAKGLRECALNAIENDISFVPDWGKNRIESMIEGRPDWCISRQRTWGVP 486
FRATPQWFI+MD LR AL AI + ++PDWG+ RIE+M+ RPDWCISRQRTWGVP
Sbjct 418 FRATPQWFIAMDKGELRRQALEAI-GQVQWIPDWGQARIEAMVGNRPDWCISRQRTWGVP 476
Query 487 IPFFVHKDTNELHPRTPELIEEVAQLIEHEGIDAWFNREAKDFIGADAEHYNAVRDTLDV 546
IP FVHK+T LHP T LIEE+A+ IE GIDAWF + + +GA+A+ Y + DTLDV
Sbjct 477 IPLFVHKETGALHPDTDRLIEEIAKKIETAGIDAWFELDPAELLGAEADRYGKIGDTLDV 536
Query 547 WFDSGTTHYAVLRQREELTDPADLYLEGSDQHRGWFQSSLLTSIAINERAPYKGLLTHGF 606
WFDSG TH+AVL Q +L PADLYLEGSDQHRGWFQSSL+TS+A++ +APYK +LTHGF
Sbjct 537 WFDSGVTHHAVLAQNPDLAFPADLYLEGSDQHRGWFQSSLMTSVAMSGQAPYKAVLTHGF 596
Query 607 VVDEKGRKMSKSLGNIITPQDIIKDMGADGLRFWIASSDYRYEMTAGKEIFSRASDGYRR 666
VD +G+KMSKS GN++ PQ +++ +GAD LR W+A++DYR EMT EI R SD YRR
Sbjct 597 TVDAEGKKMSKSRGNVVAPQKVMQTLGADVLRLWVAATDYRGEMTVSDEILKRISDVYRR 656
Query 667 IRNTLRFLLANLNGFTPSTDALPVDQLIALDQYILQRAAEVQKTVQQAYEDMNFHIVCSA 726
IRNT R+LLANL+GF P+ + + ++ALD++++ RA +Q+ V +AYE F+ +
Sbjct 657 IRNTARYLLANLDGFDPALHLVKPEDMLALDRWVVDRALAIQQEVIEAYETYQFNTIFQK 716
Query 727 LTNFCINDLGGFYLDIIKDRQYTTKADSAARHSAQTALYHLVQAFVRWMSPILSFTAQEA 786
+FC DLG FYLD++KDRQYT K DS R S QTA+YH+ +A VRW++P+LSFTA+E
Sbjct 717 THHFCSVDLGSFYLDVLKDRQYTCKTDSLPRRSGQTAMYHIAEAMVRWLAPVLSFTAEEI 776
Query 787 WPLIPEQTEQYVFTTEWYDIPVASTAN-LISEADWQTLISVKSAVNKQIEAARNAKLVGS 845
W +P Q E+ VF +EWYD N A W ++ ++ AV+K++E R +G+
Sbjct 777 WQYLPGQREESVFLSEWYDGLFGLDENSRCDRAFWDQMLKIREAVSKELEILRVRGEIGA 836
Query 846 NLSAKVEIWAKDELQSVLNQLGDELRFVLITSQVNVYPYAEQGES---TEMDGLRVQISA 902
+L A+VE++ L L++ GDELRFVL+TS V P AE G TE+ GL ++++A
Sbjct 837 SLDAEVELFCDPPLFRKLSEAGDELRFVLLTSYATVKPAAEAGTDALPTEIPGLELKLAA 896
Query 903 AEGEKCVRCWHVLPDVNTHADHPGLCGRCIINVTGSGEVRKY 944
+ KCVRCWH DV TH DHP LCGRC+ NV G+GE+R +
Sbjct 897 SGKPKCVRCWHHRHDVGTHPDHPELCGRCVDNVAGTGELRTF 938
>A4Y4A4 Isoleucine--tRNA ligase [Shewanella putrefaciens (strain
CN-32 / ATCC BAA-453)]
Length=940
Score = 1102 bits (2851), Expect = 0.0
Identities = 532/940 (57%), Positives = 680/940 (72%), Gaps = 8/940 (1%)
Query 12 DYKATLNLPGTEFAMKANLAVREVKWLEEWYADNIYQKIRASRIGKKKYVLHDGPPYANG 71
DYK TLNLP TEF M+ NLA RE + LE W D +YQ+IR SRIG+ ++LHDGPPYANG
Sbjct 3 DYKFTLNLPETEFPMRGNLANREPEMLERWTKDGLYQQIRDSRIGRTPFILHDGPPYANG 62
Query 72 QIHLGHAVNKVLKDIIVKSRVMDGFDAPYVPGWDCHGLPIELKVEEKVGKVGVKVDASTF 131
IH+GH+VNK+LKDIIVKS+ M GFDAPYVPGWDCHGLPIELKVE+KVGK G K+ A+ F
Sbjct 63 SIHIGHSVNKILKDIIVKSKTMSGFDAPYVPGWDCHGLPIELKVEQKVGKPGQKITAAEF 122
Query 132 RKACREYALSQVDLQRKDFIRMGVFGDWQDPYLTMNFKQEADIVRSLGEIQKAGHIEPGL 191
R+ CR+YA QV+ QR+DFIR+GV GDWQ+PYLTM+F EA+IVRSL ++ ++GH+ G+
Sbjct 123 REECRKYAAEQVNGQREDFIRLGVLGDWQNPYLTMDFSTEANIVRSLSKVIESGHLHKGV 182
Query 192 KPVNWCIDCGSALAEAEVEYEDKKSDAIDVGFGVVDLNDLSARLNV-EVQDPTDIVIWTT 250
KPV+WC DCGSALAEAEVEYEDK S AIDV F D ++A+ V + P +VIWTT
Sbjct 183 KPVHWCTDCGSALAEAEVEYEDKTSPAIDVAFVAADSKAVAAKFGVSDYSHPVSMVIWTT 242
Query 251 TPWTLPANQAVALHAEIDYQLVQVQSDRGTQNFILAKDLVESAIARYKLENPVVLADFKG 310
TPWTLPAN+A++L E+DY LV+ + D TQ ILA+ LVES + RY +E+ VL KG
Sbjct 243 TPWTLPANRALSLSPELDYSLVEFEKDGVTQALILAEVLVESCLTRYNVESHTVLGTTKG 302
Query 311 AVLELLQLQHPLLADRQVPVILGEHVIATSGTGAVHTAPGHGTDDYKVGLIYNLKVDNPV 370
A LEL+ HP L D VP ILG+HV +GTG VHTAPGHG DD+ VG Y L+V NPV
Sbjct 303 AALELVCFNHPFL-DFDVPAILGDHVTTDAGTGIVHTAPGHGQDDFVVGQKYGLEVANPV 361
Query 371 GGNGVYLPTAPIFSGEHIYKANPQIIEALGATGRLWAHQPIVHSYPHCWRHKTPIIFRAT 430
G NGVY P F+G+H++KAN ++ L G L H HSYPHCWRHKTPIIFRAT
Sbjct 362 GDNGVYKPDTKYFAGQHVFKANDNVVALLREKGALLNHVAYRHSYPHCWRHKTPIIFRAT 421
Query 431 PQWFISMDAKGLRECALNAIENDISFVPDWGKNRIESMIEGRPDWCISRQRTWGVPIPFF 490
PQWFISMD GLR AL IE ++PDWG++RIE M+E RPDWCISRQRTWGVPI F
Sbjct 422 PQWFISMDNHGLRTQALKEIE-QTQWIPDWGQSRIEKMVENRPDWCISRQRTWGVPITLF 480
Query 491 VHKDTNELHPRTPELIEEVAQLIEHEGIDAWFNREAKDFIGADAEHYNAVRDTLDVWFDS 550
V+++T ELHP + L+E VA IE +GI AW++ +A + +G +A+ Y V DTLDVW+DS
Sbjct 481 VNRETEELHPDSVSLMERVANRIEQQGIQAWWDLDAAELLGDEADQYRKVTDTLDVWYDS 540
Query 551 GTTHYAVLRQREEL-TDPADLYLEGSDQHRGWFQSSLLTSIAINERAPYKGLLTHGFVVD 609
G+T +V+ R E DLYLEGSDQHRGWF SSL+ S A+N +APYK +LTHGF VD
Sbjct 541 GSTFSSVVAARPEFHGHGVDLYLEGSDQHRGWFMSSLMISTAMNGKAPYKQVLTHGFTVD 600
Query 610 EKGRKMSKSLGNIITPQDIIKDMGADGLRFWIASSDYRYEMTAGKEIFSRASDGYRRIRN 669
KGRKMSKS+GN+I PQ + +GAD LR W+A++DY EMT EI +R++D YRRIRN
Sbjct 601 GKGRKMSKSIGNVIAPQTVTNKLGADILRLWVAATDYSGEMTVSDEILNRSADAYRRIRN 660
Query 670 TLRFLLANLNGFTPSTDALPVDQLIALDQYILQRAAEVQKTVQQAYEDMNFHIVCSALTN 729
T RFLLANLNGF P+ D + V+ ++ALD+++++RAA +Q+ + +AY+ NFHIV L
Sbjct 661 TARFLLANLNGFDPAKDLVAVEDMVALDRWVVRRAAALQQEIIEAYDQYNFHIVTQKLMQ 720
Query 730 FCINDLGGFYLDIIKDRQYTTKADSAARHSAQTALYHLVQAFVRWMSPILSFTAQEAWPL 789
FC +LG FYLDIIKDRQYT K + AR S Q+AL+H+ +A VRW++P+LSFTA E W L
Sbjct 721 FCSVELGSFYLDIIKDRQYTAKQEGHARRSCQSALFHIAEAMVRWIAPVLSFTADEVWQL 780
Query 790 IPEQTEQYVFTTEWYD-IPVASTANLISEADWQTLISVKSAVNKQIEAARNAKLVGSNLS 848
+P + + YVFT EWY + + A +S+ WQ L++V++ VNK IE AR K +G +L
Sbjct 781 LPGERDAYVFTQEWYQGLKSVTLATDLSDDYWQQLLAVRNEVNKVIEQARRDKRIGGSLE 840
Query 849 AKVEIWAKDELQSVLNQLGDELRFVLITSQVNVYPYAE---QGESTEMDGLRVQISAAEG 905
A+V ++A L L +GDELRFVL+TS+ V P A+ + TE+ L++ ++++
Sbjct 841 AEVTLFADATLTEQLTHIGDELRFVLLTSEAKVLPLADATTEAVETELASLKLVVASSTA 900
Query 906 EKCVRCWHVLPDVNTHADHPGLCGRCIINVTGSGEVRKYA 945
EKC RCWH +V T HP LC RC+ N+ G GEVR++A
Sbjct 901 EKCERCWHHREEVGTIEAHPTLCTRCVTNIEGDGEVRQFA 940
>A8FSI2 Isoleucine--tRNA ligase [Shewanella sediminis (strain
HAW-EB3)]
Length=940
Score = 1102 bits (2850), Expect = 0.0
Identities = 539/942 (57%), Positives = 676/942 (72%), Gaps = 12/942 (1%)
Query 12 DYKATLNLPGTEFAMKANLAVREVKWLEEWYADNIYQKIRASRIGKKKYVLHDGPPYANG 71
DYK+TLNLP TEF M+ NLA RE L+ W D +YQ+IR SRIG+K ++LHDGPPYANG
Sbjct 3 DYKSTLNLPETEFPMRGNLANREPVMLKSWTEDGLYQQIRDSRIGRKPFILHDGPPYANG 62
Query 72 QIHLGHAVNKVLKDIIVKSRVMDGFDAPYVPGWDCHGLPIELKVEEKVGKVGVKVDASTF 131
IH+GH+VNK+LKDIIVKS+ + GFDAPY+PGWDCHGLPIELKVE+KVGK G KV A+ F
Sbjct 63 SIHIGHSVNKILKDIIVKSKTLSGFDAPYIPGWDCHGLPIELKVEQKVGKPGHKVTAAQF 122
Query 132 RKACREYALSQVDLQRKDFIRMGVFGDWQDPYLTMNFKQEADIVRSLGEIQKAGHIEPGL 191
R+ CREYA QVD QR+DFIR+GVF DW PYLTM+F EA+IVRSL ++ +GH+ G+
Sbjct 123 REKCREYAAKQVDGQREDFIRLGVFADWNKPYLTMDFDTEANIVRSLAKVIDSGHLHKGV 182
Query 192 KPVNWCIDCGSALAEAEVEYEDKKSDAIDVGFGVVDLNDLSARLNVEVQDPT---DIVIW 248
KPV+WC DCGSALAEAEVEYEDKKS AIDV F D L A+ +VQD T +VIW
Sbjct 183 KPVHWCTDCGSALAEAEVEYEDKKSPAIDVAFAATDKAALLAKF--DVQDCTGSASMVIW 240
Query 249 TTTPWTLPANQAVALHAEIDYQLVQVQSDRGTQNFILAKDLVESAIARYKLENPVVLADF 308
TTTPWTLPAN+A+++ E+DY LV+ D T ILA LVES + RY +E+ L
Sbjct 241 TTTPWTLPANRALSVSPELDYVLVEFVKDGATSTVILADALVESCMERYGVESHKALGKA 300
Query 309 KGAVLELLQLQHPLLADRQVPVILGEHVIATSGTGAVHTAPGHGTDDYKVGLIYNLKVDN 368
KG LELL+ HP D VPVILG+HV SGTG VHTAPGHG DD+ VG Y L+V N
Sbjct 301 KGQELELLRFNHPFY-DFDVPVILGDHVTVDSGTGVVHTAPGHGQDDFVVGQKYGLEVAN 359
Query 369 PVGGNGVYLPTAPIFSGEHIYKANPQIIEALGATGRLWAHQPIVHSYPHCWRHKTPIIFR 428
PVG NGVY IF+G+H++KAN ++ L G L H+ I+HSYPHCWRHKTPIIFR
Sbjct 360 PVGDNGVYKADTEIFAGQHVFKANDNVVALLEEKGALIKHEKIMHSYPHCWRHKTPIIFR 419
Query 429 ATPQWFISMDAKGLRECALNAIENDISFVPDWGKNRIESMIEGRPDWCISRQRTWGVPIP 488
ATPQWFISMD KGLR+ AL IE ++PDWG++RIE M+E RPDWCISRQRTWGVPI
Sbjct 420 ATPQWFISMDQKGLRKQALGEIE-QTQWIPDWGQSRIEKMVENRPDWCISRQRTWGVPIT 478
Query 489 FFVHKDTNELHPRTPELIEEVAQLIEHEGIDAWFNREAKDFIGADAEHYNAVRDTLDVWF 548
FVH++T ELHP + L+E VA IE EGI AW++ +A++ +G +AE Y V DTLDVW+
Sbjct 479 LFVHRETEELHPDSISLMERVANRIEREGIQAWWDLDAQELLGDEAEQYRKVTDTLDVWY 538
Query 549 DSGTTHYAVLRQREELT-DPADLYLEGSDQHRGWFQSSLLTSIAINERAPYKGLLTHGFV 607
DSG++ +V+ R E DLYLEGSDQHRGWF SSL+ S A+N +APYK +LTHGF
Sbjct 539 DSGSSFSSVVASRPEYQGHEIDLYLEGSDQHRGWFMSSLMISTAMNGKAPYKQVLTHGFT 598
Query 608 VDEKGRKMSKSLGNIITPQDIIKDMGADGLRFWIASSDYRYEMTAGKEIFSRASDGYRRI 667
VD GRKMSKS+GN+I PQ + +GAD LR W+A++DY EMT EI R++D YRRI
Sbjct 599 VDGNGRKMSKSIGNVIAPQTVTNKLGADILRLWVAATDYSGEMTVSDEILKRSADAYRRI 658
Query 668 RNTLRFLLANLNGFTPSTDALPVDQLIALDQYILQRAAEVQKTVQQAYEDMNFHIVCSAL 727
RNT RFLLAN+NGF P D + V++++ALD+++++RAA +Q+ + +AYE NFH+V L
Sbjct 659 RNTARFLLANINGFDPVNDLVAVEEMVALDRWVVRRAAALQEELIEAYEQYNFHVVTQKL 718
Query 728 TNFCINDLGGFYLDIIKDRQYTTKADSAARHSAQTALYHLVQAFVRWMSPILSFTAQEAW 787
FC +LG FYLDIIKDRQYT K DS AR S Q+ALY + +A VRW++PILSFTA E W
Sbjct 719 MQFCSVELGSFYLDIIKDRQYTAKGDSVARRSCQSALYLISEAMVRWIAPILSFTADEIW 778
Query 788 PLIPEQTEQYVFTTEWYD-IPVASTANLISEADWQTLISVKSAVNKQIEAARNAKLVGSN 846
L+P + E+YVFT EWY + + + +S+ W+ L++V+ VNK IE AR K +G +
Sbjct 779 QLLPGEREKYVFTQEWYQGLESVTLDSDLSDEYWEQLLTVRGEVNKVIEQARREKQIGGS 838
Query 847 LSAKVEIWAKDELQSVLNQLGDELRFVLITSQVNVYPYAE---QGESTEMDGLRVQISAA 903
L A++ ++A D L L LGDELRFVL+TS+ + + TEM L++ + A
Sbjct 839 LEAEITLYADDALSQALATLGDELRFVLLTSKTQIVALSSAPADAIETEMTSLKLGLHKA 898
Query 904 EGEKCVRCWHVLPDVNTHADHPGLCGRCIINVTGSGEVRKYA 945
E EKC RCWH DV HP LC RC+ N+ G GEVR++A
Sbjct 899 ESEKCERCWHHREDVGQVEAHPTLCTRCVTNIEGDGEVRQFA 940
>A1RMM6 Isoleucine--tRNA ligase [Shewanella sp. (strain W3-18-1)]
Length=940
Score = 1101 bits (2847), Expect = 0.0
Identities = 531/940 (56%), Positives = 680/940 (72%), Gaps = 8/940 (1%)
Query 12 DYKATLNLPGTEFAMKANLAVREVKWLEEWYADNIYQKIRASRIGKKKYVLHDGPPYANG 71
DYK TLNLP TEF M+ NLA RE + LE W D +YQ+IR SRIG+ ++LHDGPPYANG
Sbjct 3 DYKFTLNLPETEFPMRGNLANREPEMLERWTKDGLYQQIRDSRIGRTPFILHDGPPYANG 62
Query 72 QIHLGHAVNKVLKDIIVKSRVMDGFDAPYVPGWDCHGLPIELKVEEKVGKVGVKVDASTF 131
IH+GH+VNK+LKDIIVKS+ M GFDAPYVPGWDCHGLPIELKVE+KVGK G K+ A+ F
Sbjct 63 SIHIGHSVNKILKDIIVKSKTMSGFDAPYVPGWDCHGLPIELKVEQKVGKPGQKITAAEF 122
Query 132 RKACREYALSQVDLQRKDFIRMGVFGDWQDPYLTMNFKQEADIVRSLGEIQKAGHIEPGL 191
R+ CR+YA QV+ QR+DFIR+GV GDWQ+PYLTM+F EA+IVRSL ++ ++GH+ G+
Sbjct 123 REECRKYAAEQVNGQREDFIRLGVLGDWQNPYLTMDFSTEANIVRSLSKVIESGHLHKGV 182
Query 192 KPVNWCIDCGSALAEAEVEYEDKKSDAIDVGFGVVDLNDLSARLNV-EVQDPTDIVIWTT 250
KPV+WC DCGSALAEAEVEYEDK S AIDV F D ++A+ V + P +VIWTT
Sbjct 183 KPVHWCTDCGSALAEAEVEYEDKTSPAIDVAFVAADSKAVAAKFGVSDYSHPVSMVIWTT 242
Query 251 TPWTLPANQAVALHAEIDYQLVQVQSDRGTQNFILAKDLVESAIARYKLENPVVLADFKG 310
TPWTLPAN+A++L E+DY LV+ + D TQ ILA+ LVES + RY +E+ VL KG
Sbjct 243 TPWTLPANRALSLSPELDYSLVEFEKDGVTQALILAEVLVESCLTRYNVESHTVLGTTKG 302
Query 311 AVLELLQLQHPLLADRQVPVILGEHVIATSGTGAVHTAPGHGTDDYKVGLIYNLKVDNPV 370
A LEL+ HP L D VP ILG+HV +GTG VHTAPGHG DD+ VG Y L+V NPV
Sbjct 303 AALELVCFNHPFL-DFDVPAILGDHVTTDAGTGIVHTAPGHGQDDFVVGQKYGLEVANPV 361
Query 371 GGNGVYLPTAPIFSGEHIYKANPQIIEALGATGRLWAHQPIVHSYPHCWRHKTPIIFRAT 430
G NGVY P F+G+H++KAN ++ L G L H HSYPHCWRHKTPIIFRAT
Sbjct 362 GDNGVYKPDTKYFAGQHVFKANDNVVALLREKGALLNHVAYRHSYPHCWRHKTPIIFRAT 421
Query 431 PQWFISMDAKGLRECALNAIENDISFVPDWGKNRIESMIEGRPDWCISRQRTWGVPIPFF 490
PQWFISMD GLR AL IE ++PDWG++RIE M+E RPDWCISRQRTWGVPI F
Sbjct 422 PQWFISMDNHGLRTQALKEIE-QTQWIPDWGQSRIEKMVENRPDWCISRQRTWGVPITLF 480
Query 491 VHKDTNELHPRTPELIEEVAQLIEHEGIDAWFNREAKDFIGADAEHYNAVRDTLDVWFDS 550
V+++T ELHP + L+E VA IE +GI AW++ +A + +G +A+ Y V DTLDVW+DS
Sbjct 481 VNRETEELHPDSVSLMERVANRIEQQGIQAWWDLDAAELLGDEADQYRKVTDTLDVWYDS 540
Query 551 GTTHYAVLRQREEL-TDPADLYLEGSDQHRGWFQSSLLTSIAINERAPYKGLLTHGFVVD 609
G+T +V+ R E DLYLEGSDQHRGWF SSL+ S A+N +APYK +LTHGF VD
Sbjct 541 GSTFSSVVAARPEFHGHGVDLYLEGSDQHRGWFMSSLMISTAMNGKAPYKQVLTHGFTVD 600
Query 610 EKGRKMSKSLGNIITPQDIIKDMGADGLRFWIASSDYRYEMTAGKEIFSRASDGYRRIRN 669
KGRKMSKS+GN+I PQ + +GAD LR W+A++DY EMT EI +R++D YRRIRN
Sbjct 601 GKGRKMSKSIGNVIAPQTVTNKLGADILRLWVAATDYSGEMTVSDEILNRSADAYRRIRN 660
Query 670 TLRFLLANLNGFTPSTDALPVDQLIALDQYILQRAAEVQKTVQQAYEDMNFHIVCSALTN 729
T RFLLANLNGF P+ D + V+ ++ALD+++++RAA +Q+ + +AY+ NFHIV L
Sbjct 661 TARFLLANLNGFDPAKDLVAVEDMVALDRWVVRRAAALQQEIIEAYDQYNFHIVTQKLMQ 720
Query 730 FCINDLGGFYLDIIKDRQYTTKADSAARHSAQTALYHLVQAFVRWMSPILSFTAQEAWPL 789
FC +LG FYLDIIKDRQYT K + AR S Q+AL+H+ +A VRW++P+LSFTA E W L
Sbjct 721 FCSVELGSFYLDIIKDRQYTAKQEGHARRSCQSALFHIAEAMVRWIAPVLSFTADEVWQL 780
Query 790 IPEQTEQYVFTTEWYD-IPVASTANLISEADWQTLISVKSAVNKQIEAARNAKLVGSNLS 848
+P + + YVFT EWY + + A +S+ WQ L++V++ VNK IE AR K +G +L
Sbjct 781 LPGERDAYVFTQEWYQGLKSVTLATDLSDDYWQQLLAVRNEVNKVIEQARRDKRIGGSLE 840
Query 849 AKVEIWAKDELQSVLNQLGDELRFVLITSQVNVYPYAE---QGESTEMDGLRVQISAAEG 905
A+V ++A L L +GDELRFVL+TS+ V P A+ + TE+ L++ ++++
Sbjct 841 AEVTLFADATLTEQLTHIGDELRFVLLTSEAKVLPLADATTEAVETELASLKLVVASSTA 900
Query 906 EKCVRCWHVLPDVNTHADHPGLCGRCIINVTGSGEVRKYA 945
EKC RCWH +V + HP LC RC+ N+ G GEVR++A
Sbjct 901 EKCERCWHHREEVGSIEAHPTLCTRCVTNIEGDGEVRQFA 940
>A3D1G5 Isoleucine--tRNA ligase [Shewanella baltica (strain OS155
/ ATCC BAA-1091)]
Length=940
Score = 1100 bits (2845), Expect = 0.0
Identities = 534/940 (57%), Positives = 677/940 (72%), Gaps = 8/940 (1%)
Query 12 DYKATLNLPGTEFAMKANLAVREVKWLEEWYADNIYQKIRASRIGKKKYVLHDGPPYANG 71
DYK TLNLP TEF M+ NLA RE + LE W D +YQ+IR SRIG+ ++LHDGPPYANG
Sbjct 3 DYKFTLNLPETEFPMRGNLANREPEMLERWTKDGLYQQIRDSRIGRTPFILHDGPPYANG 62
Query 72 QIHLGHAVNKVLKDIIVKSRVMDGFDAPYVPGWDCHGLPIELKVEEKVGKVGVKVDASTF 131
IH+GH+VNK+LKDIIVKS+ M GFDAPYVPGWDCHGLPIELKVE+KVGK G K+ A+ F
Sbjct 63 SIHIGHSVNKILKDIIVKSKTMSGFDAPYVPGWDCHGLPIELKVEQKVGKPGQKISAAEF 122
Query 132 RKACREYALSQVDLQRKDFIRMGVFGDWQDPYLTMNFKQEADIVRSLGEIQKAGHIEPGL 191
R+ CR+YA QV+ QR+DFIR+GV GDWQ+PYLTM+F EA+IVRSL ++ ++GH+ G+
Sbjct 123 REECRKYAAEQVNGQREDFIRLGVLGDWQNPYLTMDFSTEANIVRSLSKVIESGHLHKGV 182
Query 192 KPVNWCIDCGSALAEAEVEYEDKKSDAIDVGFGVVDLNDLSARLNV-EVQDPTDIVIWTT 250
KPV+WC DCGSALAEAEVEYEDK S AIDV F D ++A+ V + P +VIWTT
Sbjct 183 KPVHWCTDCGSALAEAEVEYEDKTSPAIDVAFVAADSKAVAAKFGVSDYSHPVSMVIWTT 242
Query 251 TPWTLPANQAVALHAEIDYQLVQVQSDRGTQNFILAKDLVESAIARYKLENPVVLADFKG 310
TPWTLPAN+A++L E+DY LV+ + D TQ ILA+ LVES + RY +E+ VL KG
Sbjct 243 TPWTLPANRALSLSPELDYSLVEFEKDGVTQALILAEVLVESCLTRYNVESHTVLGSAKG 302
Query 311 AVLELLQLQHPLLADRQVPVILGEHVIATSGTGAVHTAPGHGTDDYKVGLIYNLKVDNPV 370
A EL++ HP L D VP ILG+HV +GTG VHTAPGHG DD+ VG Y L+V NPV
Sbjct 303 AAFELVRFNHPFL-DFDVPAILGDHVTTDAGTGIVHTAPGHGQDDFVVGQKYGLEVANPV 361
Query 371 GGNGVYLPTAPIFSGEHIYKANPQIIEALGATGRLWAHQPIVHSYPHCWRHKTPIIFRAT 430
G NGVY P F+G+H++KAN ++ L L H HSYPHCWRHKTPIIFRAT
Sbjct 362 GDNGVYKPDTEYFAGQHVFKANDNVVALLREKSALLNHVAYRHSYPHCWRHKTPIIFRAT 421
Query 431 PQWFISMDAKGLRECALNAIENDISFVPDWGKNRIESMIEGRPDWCISRQRTWGVPIPFF 490
PQWFISMD GLR AL IE ++PDWG++RIE M+E RPDWCISRQRTWGVPI F
Sbjct 422 PQWFISMDNHGLRTQALKEIE-QTQWIPDWGQSRIEKMVENRPDWCISRQRTWGVPITLF 480
Query 491 VHKDTNELHPRTPELIEEVAQLIEHEGIDAWFNREAKDFIGADAEHYNAVRDTLDVWFDS 550
V+++T ELHP + L+E VA IE +GI AW++ +A + +G +AE Y V DTLDVWFDS
Sbjct 481 VNRETEELHPDSVSLMERVASRIEQQGIQAWWDLDAAELLGDEAEQYRKVTDTLDVWFDS 540
Query 551 GTTHYAVLRQREEL-TDPADLYLEGSDQHRGWFQSSLLTSIAINERAPYKGLLTHGFVVD 609
G+T +V+ R E DLYLEGSDQHRGWF SSL+ S A+N +APYK +LTHGF VD
Sbjct 541 GSTFSSVVAARPEFHGHGVDLYLEGSDQHRGWFMSSLMISTAMNGKAPYKQVLTHGFTVD 600
Query 610 EKGRKMSKSLGNIITPQDIIKDMGADGLRFWIASSDYRYEMTAGKEIFSRASDGYRRIRN 669
KGRKMSKS+GN+I PQ + +GAD LR W+A++DY EMT EI +R++D YRRIRN
Sbjct 601 GKGRKMSKSIGNVIAPQTVTNKLGADILRLWVAATDYSGEMTVSDEILNRSADAYRRIRN 660
Query 670 TLRFLLANLNGFTPSTDALPVDQLIALDQYILQRAAEVQKTVQQAYEDMNFHIVCSALTN 729
T RFLLANLNGF P+ D + V+ ++ALD+++++RAA +Q+ + +AYE NFHIV L
Sbjct 661 TARFLLANLNGFEPAKDLVAVEDMVALDRWVVRRAAALQQEIIEAYEQYNFHIVTQKLMQ 720
Query 730 FCINDLGGFYLDIIKDRQYTTKADSAARHSAQTALYHLVQAFVRWMSPILSFTAQEAWPL 789
FC +LG FYLDIIKDRQYT K + AR S Q+ALY + +A VRW++PILSFTA E W L
Sbjct 721 FCSVELGSFYLDIIKDRQYTAKQEGHARRSCQSALYLISEAMVRWIAPILSFTADEVWQL 780
Query 790 IPEQTEQYVFTTEWYD-IPVASTANLISEADWQTLISVKSAVNKQIEAARNAKLVGSNLS 848
+P + + YVFT EWY + + A +S+ WQ L++V++ VNK IE AR K +G +L
Sbjct 781 LPGERDAYVFTQEWYQGLKSVTLATDLSDDYWQQLLTVRNEVNKVIEQARRDKRIGGSLE 840
Query 849 AKVEIWAKDELQSVLNQLGDELRFVLITSQVNVYPYAE---QGESTEMDGLRVQISAAEG 905
A+V ++A L L +GDELRFVL+TS+ V P A+ + TE+ L++ ++++
Sbjct 841 AEVTLFADAALTEQLTHIGDELRFVLLTSEAKVLPLADATSEAVETELASLKLLVASSTA 900
Query 906 EKCVRCWHVLPDVNTHADHPGLCGRCIINVTGSGEVRKYA 945
EKC RCWH +V T HP LC RC+ N+ G GEVR +A
Sbjct 901 EKCERCWHHREEVGTIEAHPTLCTRCVTNIEGDGEVRLFA 940
>A8H1H3 Isoleucine--tRNA ligase [Shewanella pealeana (strain ATCC
700345 / ANG-SQ1)]
Length=940
Score = 1100 bits (2844), Expect = 0.0
Identities = 535/940 (57%), Positives = 677/940 (72%), Gaps = 8/940 (1%)
Query 12 DYKATLNLPGTEFAMKANLAVREVKWLEEWYADNIYQKIRASRIGKKKYVLHDGPPYANG 71
DYK+TLNLP TEF M+ NLA RE + L+ W + +YQ+IR SR K ++LHDGPPYANG
Sbjct 3 DYKSTLNLPETEFPMRGNLANREPEMLKSWTENGLYQQIRESRKDAKPFILHDGPPYANG 62
Query 72 QIHLGHAVNKVLKDIIVKSRVMDGFDAPYVPGWDCHGLPIELKVEEKVGKVGVKVDASTF 131
IH+GH+VNK+LKDII+KS+ M GFDAPY+PGWDCHGLPIELKVE+KVGK G KV A+ F
Sbjct 63 DIHIGHSVNKILKDIIIKSKTMSGFDAPYIPGWDCHGLPIELKVEQKVGKPGHKVTAAEF 122
Query 132 RKACREYALSQVDLQRKDFIRMGVFGDWQDPYLTMNFKQEADIVRSLGEIQKAGHIEPGL 191
R+ CREYA QVD QR DFIR+GVF DWQ+PYLTM++ EA+IVRSL ++ GH+ G+
Sbjct 123 RQKCREYAAKQVDGQRDDFIRLGVFADWQNPYLTMDYSTEANIVRSLSKVIDNGHLHKGV 182
Query 192 KPVNWCIDCGSALAEAEVEYEDKKSDAIDVGFGVVDLNDLSARLNV-EVQDPTDIVIWTT 250
KPV+WC DCGSALAEAEVEYEDK S AIDV F VVD L A+ V E +VIWTT
Sbjct 183 KPVHWCTDCGSALAEAEVEYEDKMSPAIDVAFTVVDKPALLAKFGVNEYPHNISMVIWTT 242
Query 251 TPWTLPANQAVALHAEIDYQLVQVQSDRGTQNFILAKDLVESAIARYKLENPVVLADFKG 310
TPWTLPAN+A+A+ A ++Y LV++ + Q +LA DL ES + R+ E+ VL G
Sbjct 243 TPWTLPANRALAVGANVEYTLVEMVKEGQAQALVLATDLYESCVERFGAESHTVLGTVAG 302
Query 311 AVLELLQLQHPLLADRQVPVILGEHVIATSGTGAVHTAPGHGTDDYKVGLIYNLKVDNPV 370
+ LELL+ HP D VPVILG+HV SGTG VHTAPGHG DD+ VG Y L+V NPV
Sbjct 303 SDLELLRFNHPFY-DFDVPVILGDHVTVDSGTGVVHTAPGHGQDDFVVGQKYGLEVANPV 361
Query 371 GGNGVYLPTAPIFSGEHIYKANPQIIEALGATGRLWAHQPIVHSYPHCWRHKTPIIFRAT 430
G NGVY P IF+G H++KAN ++E L G L H I HSYPHCWRHKTPIIFRAT
Sbjct 362 GDNGVYKPDTEIFAGLHVFKANKNVVELLEEKGALLNHVQIKHSYPHCWRHKTPIIFRAT 421
Query 431 PQWFISMDAKGLRECALNAIENDISFVPDWGKNRIESMIEGRPDWCISRQRTWGVPIPFF 490
PQWFISMD KGLR+ AL IE ++PDWG++RIE M+E RPDWCISRQRTWGVPI F
Sbjct 422 PQWFISMDQKGLRQQALGEIE-QTQWIPDWGQSRIEKMVENRPDWCISRQRTWGVPITLF 480
Query 491 VHKDTNELHPRTPELIEEVAQLIEHEGIDAWFNREAKDFIGADAEHYNAVRDTLDVWFDS 550
VH++T ELHP + L+E VA IE EGI AW++ +A + +G +A+ Y V DTLDVW+DS
Sbjct 481 VHRETEELHPDSVSLMERVAARIEQEGIQAWWDLDASELLGDEADQYRKVTDTLDVWYDS 540
Query 551 GTTHYAVLRQREELT-DPADLYLEGSDQHRGWFQSSLLTSIAINERAPYKGLLTHGFVVD 609
G+T +V+ R E P DLYLEGSDQHRGWF SSL+ S A+N +APYK +LTHGF VD
Sbjct 541 GSTFSSVVAARPEFNGHPIDLYLEGSDQHRGWFMSSLMISTAMNGKAPYKQVLTHGFTVD 600
Query 610 EKGRKMSKSLGNIITPQDIIKDMGADGLRFWIASSDYRYEMTAGKEIFSRASDGYRRIRN 669
+GRKMSKS+GN+I PQ + +GAD LR W+A++DY EMT +I +R++D YRRIRN
Sbjct 601 GQGRKMSKSVGNVIAPQHVTNKLGADILRLWVAATDYSGEMTVSDQILNRSADAYRRIRN 660
Query 670 TLRFLLANLNGFTPSTDALPVDQLIALDQYILQRAAEVQKTVQQAYEDMNFHIVCSALTN 729
T RFLLAN+NGF P TD + V+ ++ALD+++++RAA +Q+ + +AY+ NFH+V L
Sbjct 661 TARFLLANINGFNPETDMVAVEDMVALDRWVVRRAAALQQELLEAYDQYNFHLVTQKLMQ 720
Query 730 FCINDLGGFYLDIIKDRQYTTKADSAARHSAQTALYHLVQAFVRWMSPILSFTAQEAWPL 789
FC +LG FYLDIIKDRQYT K DS AR S Q+ALY + +A VRW++PILSFTA E W L
Sbjct 721 FCSVELGSFYLDIIKDRQYTAKEDSNARRSCQSALYLISEAMVRWIAPILSFTADEIWKL 780
Query 790 IPEQTEQYVFTTEWYD-IPVASTANLISEADWQTLISVKSAVNKQIEAARNAKLVGSNLS 848
+P + +YVFT WY + + + +S+ W L++V++ VNK IE AR K VG +L
Sbjct 781 LPGERGEYVFTETWYQGLQSVALESDLSDEYWDQLLAVRAEVNKVIENARREKQVGGSLE 840
Query 849 AKVEIWAKDELQSVLNQLGDELRFVLITSQVNVYPYAE---QGESTEMDGLRVQISAAEG 905
A+V ++A + LQ+VL LGDELRFVL+TS+ V A+ TE+ L++ + +E
Sbjct 841 AEVTLYADEALQAVLENLGDELRFVLLTSKTEVVALAQAPSDAIETELASLKLSLKKSEA 900
Query 906 EKCVRCWHVLPDVNTHADHPGLCGRCIINVTGSGEVRKYA 945
EKC RCWH DV A+HP LC RC+ N+ G GE R++A
Sbjct 901 EKCERCWHHREDVGAVAEHPTLCTRCVTNIEGEGETRQFA 940
>P00956 Isoleucine--tRNA ligase [Escherichia coli (strain K12)]
Length=938
Score = 1070 bits (2767), Expect = 0.0
Identities = 530/942 (56%), Positives = 671/942 (71%), Gaps = 14/942 (1%)
Query 12 DYKATLNLPGTEFAMKANLAVREVKWLEEWYADNIYQKIRASRIGKKKYVLHDGPPYANG 71
DYK+TLNLP T F M+ +LA RE L W D++Y IRA++ GKK ++LHDGPPYANG
Sbjct 3 DYKSTLNLPETGFPMRGDLAKREPGMLARWTDDDLYGIIRAAKKGKKTFILHDGPPYANG 62
Query 72 QIHLGHAVNKVLKDIIVKSRVMDGFDAPYVPGWDCHGLPIELKVEEKVGKVGVKVDASTF 131
IH+GH+VNK+LKDIIVKS+ + G+D+PYVPGWDCHGLPIELKVE++ GK G K A+ F
Sbjct 63 SIHIGHSVNKILKDIIVKSKGLSGYDSPYVPGWDCHGLPIELKVEQEYGKPGEKFTAAEF 122
Query 132 RKACREYALSQVDLQRKDFIRMGVFGDWQDPYLTMNFKQEADIVRSLGEIQKAGHIEPGL 191
R CREYA +QVD QRKDFIR+GV GDW PYLTM+FK EA+I+R+LG+I GH+ G
Sbjct 123 RAKCREYAATQVDGQRKDFIRLGVLGDWSHPYLTMDFKTEANIIRALGKIIGNGHLHKGA 182
Query 192 KPVNWCIDCGSALAEAEVEYEDKKSDAIDVGFGVVDLNDLSARLNV-EVQDPTDIVIWTT 250
KPV+WC+DC SALAEAEVEY DK S +IDV F VD + L A+ V V P +VIWTT
Sbjct 183 KPVHWCVDCRSALAEAEVEYYDKTSPSIDVAFQAVDQDALKAKFAVSNVNGPISLVIWTT 242
Query 251 TPWTLPANQAVALHAEIDYQLVQVQSDRGTQNFILAKDLVESAIARYKLENPVVLADFKG 310
TPWTLPAN+A+++ + DY LVQ+ Q ILAKDLVES + R + + +L KG
Sbjct 243 TPWTLPANRAISIAPDFDYALVQIDG----QAVILAKDLVESVMQRIGVTDYTILGTVKG 298
Query 311 AVLELLQLQHPLLADRQVPVILGEHVIATSGTGAVHTAPGHGTDDYKVGLIYNLKVDNPV 370
A LELL+ HP + VP ILG+HV +GTGAVHTAPGHG DDY +G Y L+ NPV
Sbjct 299 AELELLRFTHPFMG-FDVPAILGDHVTLDAGTGAVHTAPGHGPDDYVIGQKYGLETANPV 357
Query 371 GGNGVYLP-TAPIFSGEHIYKANPQIIEALGATGRLWAHQPIVHSYPHCWRHKTPIIFRA 429
G +G YLP T P G +++KAN ++ L G L + + HSYP CWRHKTPIIFRA
Sbjct 358 GPDGTYLPGTYPTLDGVNVFKANDIVVALLQEKGALLHVEKMQHSYPCCWRHKTPIIFRA 417
Query 430 TPQWFISMDAKGLRECALNAIENDISFVPDWGKNRIESMIEGRPDWCISRQRTWGVPIPF 489
TPQWF+SMD KGLR +L I+ + ++PDWG+ RIESM+ RPDWCISRQRTWGVP+
Sbjct 418 TPQWFVSMDQKGLRAQSLKEIKG-VQWIPDWGQARIESMVANRPDWCISRQRTWGVPMSL 476
Query 490 FVHKDTNELHPRTPELIEEVAQLIEHEGIDAWFNREAKDFIGADAEHYNAVRDTLDVWFD 549
FVHKDT ELHPRT EL+EEVA+ +E +GI AW++ +AK+ +G +A+ Y V DTLDVWFD
Sbjct 477 FVHKDTEELHPRTLELMEEVAKRVEVDGIQAWWDLDAKEILGDEADQYVKVPDTLDVWFD 536
Query 550 SGTTHYAVLRQREELT-DPADLYLEGSDQHRGWFQSSLLTSIAINERAPYKGLLTHGFVV 608
SG+TH +V+ R E AD+YLEGSDQHRGWF SSL+ S A+ +APY+ +LTHGF V
Sbjct 537 SGSTHSSVVDVRPEFAGHAADMYLEGSDQHRGWFMSSLMISTAMKGKAPYRQVLTHGFTV 596
Query 609 DEKGRKMSKSLGNIITPQDIIKDMGADGLRFWIASSDYRYEMTAGKEIFSRASDGYRRIR 668
D +GRKMSKS+GN ++PQD++ +GAD LR W+AS+DY EM EI RA+D YRRIR
Sbjct 597 DGQGRKMSKSIGNTVSPQDVMNKLGADILRLWVASTDYTGEMAVSDEILKRAADSYRRIR 656
Query 669 NTLRFLLANLNGFTPSTDALPVDQLIALDQYILQRAAEVQKTVQQAYEDMNFHIVCSALT 728
NT RFLLANLNGF P+ D + ++++ LD++ + A Q+ + +AYE +FH V L
Sbjct 657 NTARFLLANLNGFDPAKDMVKPEEMVVLDRWAVGCAKAAQEDILKAYEAYDFHEVVQRLM 716
Query 729 NFCINDLGGFYLDIIKDRQYTTKADSAARHSAQTALYHLVQAFVRWMSPILSFTAQEAWP 788
FC ++G FYLDIIKDRQYT KADS AR S QTALYH+ +A VRWM+PILSFTA E W
Sbjct 717 RFCSVEMGSFYLDIIKDRQYTAKADSVARRSCQTALYHIAEALVRWMAPILSFTADEVWG 776
Query 789 LIPEQTEQYVFTTEWYD-IPVASTANLISEADWQTLISVKSAVNKQIEAARNAKLVGSNL 847
+P + E+YVFT EWY+ + + + +++A W L+ V+ VNK IE AR K VG +L
Sbjct 777 YLPGEREKYVFTGEWYEGLFGLADSEAMNDAFWDELLKVRGEVNKVIEQARADKKVGGSL 836
Query 848 SAKVEIWAKDELQSVLNQLGDELRFVLITSQVNVYPY----AEQGESTEMDGLRVQISAA 903
A V ++A+ EL + L LGDELRFVL+TS V Y A+ +S + GL+V +S A
Sbjct 837 EAAVTLYAEPELSAKLTALGDELRFVLLTSGATVADYNDAPADAQQSEVLKGLKVALSKA 896
Query 904 EGEKCVRCWHVLPDVNTHADHPGLCGRCIINVTGSGEVRKYA 945
EGEKC RCWH DV A+H +CGRC+ NV G GE RK+A
Sbjct 897 EGEKCPRCWHYTQDVGKVAEHAEICGRCVSNVAGDGEKRKFA 938
>P18330 Isoleucine--tRNA ligase 1 [Pseudomonas fluorescens]
Length=943
Score = 989 bits (2556), Expect = 0.0
Identities = 498/951 (52%), Positives = 651/951 (68%), Gaps = 27/951 (3%)
Query 12 DYKATLNLPGTEFAMKANLAVREVKWLEEWYADNIYQKIRASRIGKKKYVLHDGPPYANG 71
DYKATLNLP T F MKA L RE + L+ W + +Y K+R + K+VLHDGPPYANG
Sbjct 3 DYKATLNLPDTAFPMKAGLPQREPQILQRWNSIGLYGKLREIGKDRPKFVLHDGPPYANG 62
Query 72 QIHLGHAVNKVLKDIIVKSRVMDGFDAPYVPGWDCHGLPIELKVEEKVGKVGVKVDASTF 131
IH+GHA+NK+LKD+I++S+ + GFDAPYVPGWDCHGLPIE KVE GK + A
Sbjct 63 TIHIGHALNKILKDMILRSKTLSGFDAPYVPGWDCHGLPIEHKVEVTYGK---NLGADKT 119
Query 132 RKACREYALSQVDLQRKDFIRMGVFGDWQDPYLTMNFKQEADIVRSLGEIQKAGHIEPGL 191
R+ CR YA Q++ Q+ +FIR+GV G+W +PY TMNFK EA +R+L EI K G + GL
Sbjct 120 RELCRAYATEQIEGQKSEFIRLGVLGEWDNPYKTMNFKNEAGEIRALAEIVKGGFVFKGL 179
Query 192 KPVNWCIDCGSALAEAEVEYEDKKSDAIDVGFGVVDLNDLSARLNV-EVQDPTDIVIWTT 250
KPVNWC DCGSALAEAEVEYEDKKS IDV F + D L+ + + P IVIWTT
Sbjct 180 KPVNWCFDCGSALAEAEVEYEDKKSSTIDVAFPIADDAKLAEAFGLASLAKPAAIVIWTT 239
Query 251 TPWTLPANQAVALHAEIDYQLVQVQSDRGTQNFILAKDLVESAIARYKLENPVVLADFKG 310
TPWT+PANQA+ +H E Y LV V G + +LA+++VES +ARY+L+ V+ A G
Sbjct 240 TPWTIPANQALNVHPEFTYALVDV----GDRLLVLAEEMVESCLARYELQGSVI-ATATG 294
Query 311 AVLELLQLQHPLLADRQVPVILGEHVIATSGTGAVHTAPGHGTDDYKVGLIYNLKVD--- 367
+ LEL+ +HP DR PV L ++V SGTG VH +P +G DD+ + Y + D
Sbjct 295 SALELINFRHPFY-DRLSPVYLADYVELGSGTGIVHCSPAYGVDDFVICKKYGMVNDDII 353
Query 368 NPVGGNGVYLPTAPIFSGEHIYKANPQIIEALGATGRLWAHQPIVHSYPHCWRHKTPIIF 427
NPV NGVY+P+ F G+ I+KA+ IIE L G L I HSY HCWRHKTP+I+
Sbjct 354 NPVQSNGVYVPSLEFFGGQFIFKADQPIIEKLREVGALMQTAAIQHSYMHCWRHKTPLIY 413
Query 428 RATPQWFISMDAKG-----LRECALNAIENDISFVPDWGKNRIESMIEGRPDWCISRQRT 482
RAT QWFI MD + LR +L AIE D FVP WG+ R+ SMI RPDWCISRQR
Sbjct 414 RATAQWFIGMDKEPTSGDTLRVRSLKAIE-DTKFVPSWGQARLHSMIANRPDWCISRQRN 472
Query 483 WGVPIPFFVHKDTNELHPRTPELIEEVAQLIEHEGIDAWFNREAKDFIGADAEHYNAVRD 542
WGVPIPFF++K++ ELHPRT EL+E VAQ +E +GI+AWF +A + +G +A Y+ + D
Sbjct 473 WGVPIPFFLNKESGELHPRTVELMEVVAQRVEQQGIEAWFKLDAAELLGDEAPLYDKISD 532
Query 543 TLDVWFDSGTTHYAVLRQREEL---TDP-ADLYLEGSDQHRGWFQSSLLTSIAINERAPY 598
TLDVWFDSGTTH+ VLR + T P ADLYLEGSDQHRGWF SSLLT AI+ APY
Sbjct 533 TLDVWFDSGTTHWHVLRGSHPMGHETGPRADLYLEGSDQHRGWFHSSLLTGCAIDNHAPY 592
Query 599 KGLLTHGFVVDEKGRKMSKSLGNIITPQDIIKDMGADGLRFWIASSDYRYEMTAGKEIFS 658
+ LLTHGF VDE GRKMSKSL N+I P+ I +GAD +R W+AS+DY E+ +I +
Sbjct 593 RELLTHGFTVDETGRKMSKSLKNVIEPKKINDTLGADIMRLWVASTDYSGEIAVSDQILA 652
Query 659 RASDGYRRIRNTLRFLLANLNGFTPSTDALPVDQLIALDQYILQRAAEVQKTVQQAYEDM 718
R++D YRRIRNT RF+L+NL GF P++D LP + ++ALD++ + R +Q+ +Q+ Y +
Sbjct 653 RSADAYRRIRNTARFMLSNLTGFNPASDLLPAEDMLALDRWAVDRTLLLQRELQEHYGEY 712
Query 719 NFHIVCSALTNFCINDLGGFYLDIIKDRQYTTKADSAARHSAQTALYHLVQAFVRWMSPI 778
F V S + NFC+ +LGGFYLDIIKDRQYTT A+S AR SAQTALYH+ +A VRW++PI
Sbjct 713 RFWNVYSKIHNFCVQELGGFYLDIIKDRQYTTGANSKARRSAQTALYHISEALVRWIAPI 772
Query 779 LSFTAQEAWPLIPEQTEQYVFTTEWYDIPVASTANL-ISEADWQTLISVKSAVNKQIEAA 837
L+FTA E W +P + + V WY+ A+ + W+ +++VK AVNK++E
Sbjct 773 LAFTADELWEYLPGERNESVMLNTWYEGLTELPADFELGREYWEGVMAVKVAVNKELEVQ 832
Query 838 RNAKLVGSNLSAKVEIWAKDELQSVLNQLGDELRFVLITSQVNVYPYAE---QGESTEMD 894
R AK VG NL A+V ++A+D L + L +L +ELRFVLITS ++ P+ + +TE+
Sbjct 833 RAAKAVGGNLQAEVTLFAEDGLTADLAKLSNELRFVLITSTASLAPFTQAPADAVATEVP 892
Query 895 GLRVQISAAEGEKCVRCWHVLPDVNTHADHPGLCGRCIINVTGSGEVRKYA 945
GL++++ + KC RCWH DV + +HP +CGRC+ N++G GEVR YA
Sbjct 893 GLKLKVVKSAFPKCARCWHCREDVGVNPEHPEICGRCVDNISGEGEVRHYA 943
>P46213 Isoleucine--tRNA ligase [Thermotoga maritima (strain ATCC
43589 / DSM 3109 / JCM 10099 / NBRC 100826 / MSB8)]
Length=919
Score = 741 bits (1914), Expect = 0.0
Identities = 390/941 (41%), Positives = 568/941 (60%), Gaps = 39/941 (4%)
Query 11 VDYKATLNLPGTEFAMKANLAVREVKWLEEWYADNIYQKIRASRIGKKKYVLHDGPPYAN 70
++YK TLNLP T F MKANL +E +LEEW ++Y + R GK +VLHDGPPYAN
Sbjct 1 MEYKNTLNLPKTSFPMKANLVNKEKVFLEEWEKMDLYNYVLEQRKGKPLFVLHDGPPYAN 60
Query 71 GQIHLGHAVNKVLKDIIVKSRVMDGFDAPYVPGWDCHGLPIELKVEEKVGKVGVKVDAST 130
G IH+G A+NK+LKDI+VK + M G+ APYVPGWD HGLPIE +V +++G+ ++ +
Sbjct 61 GHIHIGTALNKILKDIVVKYKTMRGYRAPYVPGWDTHGLPIEHRVSQELGEKIKEMSPAE 120
Query 131 FRKACREYALSQVDLQRKDFIRMGVFGDWQDPYLTMNFKQEADIVRSLGEIQKAGHIEPG 190
RK C E+AL VD+QR++F R+GV GDW++PY+T+ E I+ + + G++
Sbjct 121 IRKKCEEFALRFVDIQREEFKRLGVRGDWENPYITLKPDYEVKILDVFKTLVEQGNVYRS 180
Query 191 LKPVNWCIDCGSALAEAEVEYEDKKSDAIDVGFGVVDLNDLSARLNVEVQDPTD-IVIWT 249
LKP+ WC C +ALAEAE+EY D KS +I V F +DP IVIWT
Sbjct 181 LKPIYWCPRCRTALAEAEIEYHDHKSPSIYVKFR-------------SKEDPNFFIVIWT 227
Query 250 TTPWTLPANQAVALHAEIDYQLVQVQSDRGTQNFILAKDLVESAIARYKLENPVVLADFK 309
TTPWTLPAN +ALH + +Y +V+V G + +++A DL+++ ++ V+ K
Sbjct 228 TTPWTLPANVGIALHPDYEYSVVKV----GEEKWVIATDLLDAFSKETGIDCSNVVEKIK 283
Query 310 GAVLELLQLQHPLLADRQVPVILGEHVIATSGTGAVHTAPGHGTDDYKVGLI-YNLKVDN 368
G LE + HP+ DR VIL ++V +GTG VH APGHG +DY G + Y L + +
Sbjct 284 GKDLEGKEFVHPIFDDRTSRVILADYVSLETGTGCVHIAPGHGEEDYIYGHVQYGLPIVS 343
Query 369 PVGGNGVYLPTAPIFSGEHIYKANPQIIEALGATGRLWAHQPIVHSYPHCWRHKTPIIFR 428
PV G + A + G I AN IIE L G L I HSYPHCWR K P+IFR
Sbjct 344 PVDEEGRFTEEAGKYKGMFIEDANEVIIEDLKRKGILVHASSITHSYPHCWRCKGPVIFR 403
Query 429 ATPQWFISMDAKGLRECALNAIENDISFVPDWGKNRIESMIEGRPDWCISRQRTWGVPIP 488
AT QWFIS+D LR+ L I+ + ++P+WG+NRI SM+E RPDWCISRQR WG PIP
Sbjct 404 ATEQWFISVDHNNLRQKVLEEIDK-VKWIPEWGRNRIRSMVEERPDWCISRQRVWGTPIP 462
Query 489 FFVHKDTNELHPRTPELIEEVAQLIEHEGIDAWFNREAKDFIGAD-------AEHYNAVR 541
K+ E+ P++IE +++E EG +AWF +E ++ I D + +
Sbjct 463 AVKCKECGEV-VLDPKVIEHFMKIVEKEGTNAWFEKEVEELIPEDFVCPKCGKRSFEKML 521
Query 542 DTLDVWFDSGTTHYAVLRQREELTDPADLYLEGSDQHRGWFQSSLLTSIAINERAPYKGL 601
DTLDVW DSG + + +RE+ P D+YLEGSDQHRGWF SS+ ++A APYK +
Sbjct 522 DTLDVWIDSGASFEYITTKREDHPFPLDMYLEGSDQHRGWFHSSIFLAVAKRGSAPYKEV 581
Query 602 LTHGFVVDEKGRKMSKSLGNIITPQDIIKDMGADGLRFWIASSDYRYEMTAGKEIFSRAS 661
LTHGF+ DE+GRKMSKSLGN++ P ++++ GA+ LR W+ASSDY ++ I + +
Sbjct 582 LTHGFIKDEQGRKMSKSLGNVVDPMEVVEKYGAEILRLWLASSDYFNDIKISMRIVEQQT 641
Query 662 DGYRRIRNTLRFLLANLNGFTPSTDALPVDQLIALDQYILQRAAEVQKTVQQAYEDMNFH 721
+ YR+IRNT RFLL NL F P D +P ++L+ +D++ L R E+ K + Y+ F
Sbjct 642 EVYRKIRNTFRFLLGNLEDFDPELDRVPHEKLLTIDRWALGRLQEIIKRATEYYDSYEFS 701
Query 722 IVCSALTNFCINDLGGFYLDIIKDRQYTTKADSAARHSAQTALYHLVQAFVRWMSPILSF 781
V + + +C +L YLD++KDR Y DS R SAQT ++ ++ + ++ ++PI++F
Sbjct 702 KVYNLVVKYCTTELSSLYLDVVKDRLYVEAKDSIYRRSAQTVMHEILISLMKILAPIMTF 761
Query 782 TAQEAWPLIPEQTEQY--VFTTEWYDIPVASTANLISEADWQTLISVKSAVNKQIEAARN 839
T +E + + E+ +Y V W + + E D++ L+S++ V K +E R
Sbjct 762 TMEEVYSHLHEKDRKYKTVQAEYWPEYREEFIDRKLME-DFEKLLSIREDVLKALEEKRQ 820
Query 840 AKLVGSNLSAKVEIWAK-DELQSVLNQLGDELRFVLITSQVNVYPYAEQGESTEMDG--L 896
++G +L A+V + K D ++++L + D L + I S+V++ S E+ G +
Sbjct 821 QDVIGHSLDAEVVLVPKNDTIKALLEKYRDILEELFIVSKVSL-----SDASGELKGELV 875
Query 897 RVQISAAEGEKCVRCWHVLPDVNTHADHPGLCGRCIINVTG 937
V + AEGEKC RCW +++ D PG+C RC+ + G
Sbjct 876 EVTVKHAEGEKCQRCWKYTTEISASEDFPGVCPRCLAVLKG 916
>Q9XDB4 Isoleucine--tRNA ligase [Fervidobacterium pennivorans
(strain DSM 9078 / Ven5)]
Length=912
Score = 730 bits (1885), Expect = 0.0
Identities = 400/929 (43%), Positives = 558/929 (60%), Gaps = 34/929 (4%)
Query 11 VDYKATLNLPGTEFAMKANLAVREVKWLEEWYADNIYQKIRASRIGKKKYVLHDGPPYAN 70
+DYKATLNLP T F MKANL +E + L+ W IY+K +R Y+LHDGPPYAN
Sbjct 1 MDYKATLNLPQTNFQMKANLVNKEPEMLKFWEEKEIYKKTLETRANAPTYLLHDGPPYAN 60
Query 71 GQIHLGHAVNKVLKDIIVKSRVMDGFDAPYVPGWDCHGLPIELKVEEKVGKVGVKVDAST 130
G IHLG A+NK+LKD + + + M G+ P+VPGWD HGLPIE +V +G+ K +
Sbjct 61 GDIHLGTAMNKILKDFVTRYKTMRGYRVPFVPGWDTHGLPIEHRVTTSLGEEAKKKSPAE 120
Query 131 FRKACREYALSQVDLQRKDFIRMGVFGDWQDPYLTMNFKQEADIVRSLGEIQKAGHIEPG 190
RK C+E+AL VD+QR++F R+GV GDW+ PY+T++ E I+ + + G++ G
Sbjct 121 IRKLCKEFALKYVDIQREEFKRLGVKGDWEHPYITLDPDYEYHILDVFKTLVENGNVYRG 180
Query 191 LKPVNWCIDCGSALAEAEVEYEDKKSDAIDVGFGVVDLNDLSARLNVEVQDPTDIVIWTT 250
KPV WC C +ALAEAE+EY D +S +I V F +VD D T IVIWTT
Sbjct 181 NKPVYWCPTCRTALAEAEIEYHDHESPSIYVKFQMVDKPD------------TYIVIWTT 228
Query 251 TPWTLPANQAVALHAEIDYQLVQVQSDRGTQNFILAKDLVESAIARYKLENPVVLADFKG 310
TPWT+PAN A+ALH DY V+++ D + +I+A+ L++ A ++ VV F G
Sbjct 229 TPWTIPANVAIALHP--DYTYVKIKVDE--EYWIVAEGLLQKFAADVGIDFEVV-EKFVG 283
Query 311 AVLELLQLQHPLLADRQVPVILGEHVIATSGTGAVHTAPGHGTDDYKVGLIYNLKVDNPV 370
LE +HPL DR V+L ++V GTG VHTAPGHG +DY+ GL YNL V +PV
Sbjct 284 KELEGKLTKHPLY-DRTSVVVLADYVTLEDGTGCVHTAPGHGEEDYQTGLKYNLPVLSPV 342
Query 371 GGNGVYLPTAPIFSGEHIYKANPQIIEALGATGRLWAHQPIVHSYPHCWRHKTPIIFRAT 430
G + A + G I+ AN I+E L G L I HSYPHCWR K P++FRAT
Sbjct 343 DDEGRFTKEAGKYEGLKIWDANKVIVEDLKNNGSLIKAGKISHSYPHCWRCKGPVMFRAT 402
Query 431 PQWFISMDAKGLRECALNAIENDISFVPDWGKNRIESMIEGRPDWCISRQRTWGVPIPFF 490
PQWFIS+D LR L I+ + + P WG+ RI +M++ RPDW ISRQR WGVPIP
Sbjct 403 PQWFISVDKNNLRGKVLEEIKK-VKWYPAWGETRITAMVQERPDWTISRQRVWGVPIPAV 461
Query 491 VHKDTNELHPRTPELIEEVAQLIEHEGIDAWFNREAKDFIGAD-------AEHYNAVRDT 543
KD E+ P++IE A +++ +G DAWF + + I AD ++++ DT
Sbjct 462 KCKDCGEV-TLEPKVIEHFANIVKEKGTDAWFELDVNELIPADFKCPACGSKNFEKTHDT 520
Query 544 LDVWFDSGTTHYAVLRQREELTDPADLYLEGSDQHRGWFQSSLLTSIAINERAPYKGLLT 603
LDVW DSG + AV+R + E P DLYLEG DQHRGWFQSS+ S A AP+K ++T
Sbjct 521 LDVWIDSGCSWEAVIRSKGE-RFPVDLYLEGDDQHRGWFQSSIFLSTAKAGTAPFKAVVT 579
Query 604 HGFVVDEKGRKMSKSLGNIITPQDIIKDMGADGLRFWIASSDYRYEMTAGKEIFSRASDG 663
HGF+ DE+GRKMSKSLGN+I P +I+ GAD LR W+AS+D+ + GK I + +
Sbjct 580 HGFIKDEQGRKMSKSLGNVIDPMEIVNKYGADILRLWVASTDFFDNIRVGKNIIEQQVEV 639
Query 664 YRRIRNTLRFLLANLNGFTPSTDALPVDQLIALDQYILQRAAEVQKTVQQAYEDMNFHIV 723
YR++RNTLR+LL+NL FT D LP ++L+ LD++ L R + + + Q YE + V
Sbjct 640 YRKLRNTLRYLLSNLYDFT-EADLLPYEKLLPLDKWALGRLQKFIEQITQYYEGFEYSKV 698
Query 724 CSALTNFCINDLGGFYLDIIKDRQYTTKADSAARHSAQTALYHLVQAFVRWMSPILSFTA 783
+A +C +L YLDI+KDR Y DS R SAQTAL+++++A ++ ++PI+ FTA
Sbjct 699 YNATVKYCTTELSAVYLDILKDRLYVEAKDSIYRRSAQTALHYILEALIKILAPIIPFTA 758
Query 784 QEAWPLIPEQTEQYVFTTEWYDIPVASTANLISEADWQTLISVKSAVNKQIEAARNAKLV 843
+EA+ + + V W ++ + E ++ L+ ++ V K +E AR + ++
Sbjct 759 EEAYQESHLKRYESVHLEYWPEVRKEFIDEALLE-EFDHLLLIRDDVLKALENARASDII 817
Query 844 GSNLSAKVEIWAK-DELQSVLNQLGDELRFVLITSQVNVYPYAEQGESTEMDGLRVQISA 902
G +L A V I AK +EL+++L + L I S+V + +E V +
Sbjct 818 GHSLDAHVIIEAKNEELKNLLRKYESLLEEFFIVSKVTL---SENISGLNGQFANVLVQR 874
Query 903 AEGEKCVRCWHVLPDVNTHADHPGLCGRC 931
AEG+KC RCW PD +HP C RC
Sbjct 875 AEGQKCQRCWKYHPDTGKDLEHPETCPRC 903
>P41972 Isoleucine--tRNA ligase [Staphylococcus aureus]
Length=917
Score = 723 bits (1865), Expect = 0.0
Identities = 397/936 (42%), Positives = 549/936 (59%), Gaps = 42/936 (4%)
Query 11 VDYKATLNLPGTEFAMKANLAVREVKWLEEWYADNIYQKIRASRIGKKKYVLHDGPPYAN 70
+DYK TL +P T+F M+ L +E + E+W A++ Y K G + ++LHDGPPYAN
Sbjct 1 MDYKETLLMPKTDFPMRGGLPNKEPQIQEKWDAEDQYHKALEKNKGNETFILHDGPPYAN 60
Query 71 GQIHLGHAVNKVLKDIIVKSRVMDGFDAPYVPGWDCHGLPIELKVEEKVGKVGVKVDAST 130
G +H+GHA+NK+LKD IV+ + M GF APYVPGWD HGLPIE + +K G K+ +
Sbjct 61 GNLHMGHALNKILKDFIVRYKTMQGFYAPYVPGWDTHGLPIEQALTKK-GVDRKKMSTAE 119
Query 131 FRKACREYALSQVDLQRKDFIRMGVFGDWQDPYLTMNFKQEADIVRSLGEIQKAGHIEPG 190
FR+ C+E+AL Q++LQ+KDF R+GV GD+ DPY+T+ + EA +R GE+ G I G
Sbjct 120 FREKCKEFALEQIELQKKDFRRLGVRGDFNDPYITLKPEYEAAQIRIFGEMADKGLIYKG 179
Query 191 LKPVNWCIDCGSALAEAEVEYEDKKSDAIDVGFGVVDLNDLSARLNVEVQDPTDIVIWTT 250
KPV W S+LAEAE+EY DK+S +I V F V D + V +IWTT
Sbjct 180 KKPVYWSPSSESSLAEAEIEYHDKRSASIYVAFNVKDDKGV-------VDADAKFIIWTT 232
Query 251 TPWTLPANQAVALHAEIDYQLVQVQSDRGTQNFILAK---DLVESAI----ARYKLENPV 303
TPWT+P+N A+ +H E+ Y V ++ +I+A+ D V A+ A KLE
Sbjct 233 TPWTIPSNVAITVHPELKYGQYNVNGEK----YIIAEALSDAVAEALDWDKASIKLEK-- 286
Query 304 VLADFKGAVLELLQLQHPLLADRQVPVILGEHVIATSGTGAVHTAPGHGTDDYKVGLIYN 363
++ G LE + QHP L DR+ VI G+HV +GTG VHTAPGHG DDY VG Y
Sbjct 287 ---EYTGKELEYVVAQHPFL-DRESLVINGDHVTTDAGTGCVHTAPGHGEDDYIVGQKYE 342
Query 364 LKVDNPVGGNGVYLPTAPIFSGEHIYKANPQIIEALGATGRLWAHQPIVHSYPHCWRHKT 423
L V +P+ GV+ F G KAN + + L G L I HSYPH WR K
Sbjct 343 LPVISPIDDKGVFTEEGGQFEGMFYDKANKAVTDLLTEKGALLKLDFITHSYPHDWRTKK 402
Query 424 PIIFRATPQWFISMDAKGLRECALNAIENDISFVPDWGKNRIESMIEGRPDWCISRQRTW 483
P+IFRATPQWF S+ +R+ L+AIEN +F +WGK RI +M+ R +W ISRQR W
Sbjct 403 PVIFRATPQWFASISK--VRQDILDAIENT-NFKVNWGKTRIYNMVRDRGEWVISRQRVW 459
Query 484 GVPIPFFVHKDTNELHPRTPELIEEVAQLIEHEGIDAWFNREAKDFIGADAEH------- 536
GVP+P F ++ + T E + VA L G + WF REAKD + H
Sbjct 460 GVPLPVFYAENGEII--MTKETVNHVADLFAEHGSNIWFEREAKDLLPEGFTHPGSPNGT 517
Query 537 YNAVRDTLDVWFDSGTTHYAVLRQREELTDPADLYLEGSDQHRGWFQSSLLTSIAINERA 596
+ D +DVWFDSG++H VL R EL+ PAD+YLEGSDQ+RGWF SS+ TS+A +
Sbjct 518 FTKETDIMDVWFDSGSSHRGVLETRPELSFPADMYLEGSDQYRGWFNSSITTSVATRGVS 577
Query 597 PYKGLLTHGFVVDEKGRKMSKSLGNIITPQDIIKDMGADGLRFWIASSDYRYEMTAGKEI 656
PYK LL+HGFV+D +G+KMSKSLGN+I P ++K GAD R W++S+DY ++ EI
Sbjct 578 PYKFLLSHGFVMDGEGKKMSKSLGNVIVPDQVVKQKGADIARLWVSSTDYLADVRISDEI 637
Query 657 FSRASDGYRRIRNTLRFLLANLNGFTPSTDALPVDQLIALDQYILQRAAEVQKTVQQAYE 716
+ SD YR+IRNTLRF+L N+N F P TD++P +L+ +D+Y+L R E + YE
Sbjct 638 LKQTSDVYRKIRNTLRFMLGNINDFNPDTDSIPESELLEVDRYLLNRLREFTASTINNYE 697
Query 717 DMNFHIVCSALTNFCINDLGGFYLDIIKDRQYTTKADSAARHSAQTALYHLVQAFVRWMS 776
+ ++ + + NF +L FYLD KD Y + DS R S QT LY ++ + ++
Sbjct 698 NFDYLNIYQEVQNFINVELSNFYLDYGKDILYIEQRDSHIRRSMQTVLYQILVDMTKLLA 757
Query 777 PILSFTAQEAWPLIPEQTEQYVFTTEWYDIPVASTANLISEADWQTLISVKSAVNKQIEA 836
PIL TA+E W P E+ V D+P + W+T ++++ VN+ +E
Sbjct 758 PILVHTAEEVWSHTPHVKEESVHLA---DMPKVVEVDQALLDKWRTFMNLRDDVNRALET 814
Query 837 ARNAKLVGSNLSAKVEIWAKDELQ-SVLNQLGDELRFVLITSQVNVYPYAEQGESTEMDG 895
ARN K++G +L AKV I + D+ S D L + I SQV V + ++T +
Sbjct 815 ARNEKVIGKSLEAKVTIASNDKFNASEFLTSFDALHQLFIVSQVKVVDKLDD-QATAYEH 873
Query 896 LRVQISAAEGEKCVRCWHVLPDVNTHADHPGLCGRC 931
+ I A+GEKC RCW+ D+ + LC RC
Sbjct 874 GDIVIEHADGEKCERCWNYSEDLGAVDELTHLCPRC 909
>Q846V6 Isoleucine--tRNA ligase [Staphylococcus epidermidis]
Length=871
Score = 686 bits (1771), Expect = 0.0
Identities = 372/880 (42%), Positives = 525/880 (60%), Gaps = 29/880 (3%)
Query 11 VDYKATLNLPGTEFAMKANLAVREVKWLEEWYADNIYQKIRASRIGKKKYVLHDGPPYAN 70
++YK TL +P T+F M+ L +E + E W D+ Y+K ++LHDGPPYAN
Sbjct 1 MNYKDTLLMPKTDFPMRGGLPNKEPQIQEMWDNDDQYRKALEKNKNNPSFILHDGPPYAN 60
Query 71 GQIHLGHAVNKVLKDIIVKSRVMDGFDAPYVPGWDCHGLPIELKVEEKVGKVGVKVDAST 130
G +H+GHA+NK++KD IV+ + M GF APYVPGWD HGLPIE + +K G K+ +
Sbjct 61 GNLHMGHALNKIIKDFIVRYKTMQGFYAPYVPGWDTHGLPIEQALTKK-GVDRKKMSVAE 119
Query 131 FRKACREYALSQVDLQRKDFIRMGVFGDWQDPYLTMNFKQEADIVRSLGEIQKAGHIEPG 190
FR+ C+E+AL Q+D+Q+KDF R+GV GD+ +PY+T+ + EA +R GE+ G I G
Sbjct 120 FREKCKEFALKQIDIQKKDFKRLGVRGDFNNPYITLTPEYEAAQIRLFGEMADKGLIYKG 179
Query 191 LKPVNWCIDCGSALAEAEVEYEDKKSDAIDVGFGVVDLNDLSARLNVEVQDPTDIVIWTT 250
KPV W S+LAEAE+EY DK+S +I V F D+ D +++ + Q +IWTT
Sbjct 180 KKPVYWSPSSESSLAEAEIEYHDKRSASIYVAF---DVKDSKGKVDSDAQ----FIIWTT 232
Query 251 TPWTLPANQAVALHAEIDYQLVQVQSDRGTQNFILAKDLVESAIARYKLENPVVLADFKG 310
TPWT+P+N A+ +H E+ Y V + L++++ E+ + ++ + +F G
Sbjct 233 TPWTIPSNVAITVHPELKYGQYNVDGHKYIVAQALSEEVAEAL--GWDKDSIQLEKEFTG 290
Query 311 AVLELLQLQHPLLADRQVPVILGEHVIATSGTGAVHTAPGHGTDDYKVGLIYNLKVDNPV 370
LE ++ QHP L DR VI GEHV +GTG VHTAPGHG DDY VG Y+L V +P+
Sbjct 291 KELEFVEAQHPFL-DRVSLVINGEHVTTDAGTGCVHTAPGHGEDDYIVGQKYDLPVISPL 349
Query 371 GGNGVYLPTAPIFSGEHIYKANPQIIEALGATGRLWAHQPIVHSYPHCWRHKTPIIFRAT 430
GV+ F G KAN + + L L I HSYPH WR K P+IFRAT
Sbjct 350 NDKGVFTEEGGPFEGMFYDKANKAVTDLLKEKDALLKLDFITHSYPHDWRTKKPVIFRAT 409
Query 431 PQWFISMDAKGLRECALNAIENDISFVPDWGKNRIESMIEGRPDWCISRQRTWGVPIPFF 490
PQWF S++ +++ L+AIE D +F DWGK RI +MI R +W ISRQR WGVP+P F
Sbjct 410 PQWFASINK--VKQDILDAIE-DTNFKVDWGKTRIYNMIRDRGEWVISRQRVWGVPLPVF 466
Query 491 VHKDTNELHPRTPELIEEVAQLIEHEGIDAWFNREAKDFIGADAEH-------YNAVRDT 543
++ + + T E + VA L E G + WF +EAK+ + H + D
Sbjct 467 YAENGDII--MTKETVNHVADLFEKYGSNIWFEKEAKELLPEGFSHPGSPNGEFTKETDI 524
Query 544 LDVWFDSGTTHYAVLRQREELTDPADLYLEGSDQHRGWFQSSLLTSIAINERAPYKGLLT 603
+DVWFDSG++H VL R EL+ PADLY EGSDQ+RGWF SS+ T++A +APYK LL+
Sbjct 525 MDVWFDSGSSHRGVLETRPELSFPADLYFEGSDQYRGWFNSSITTAVATRGQAPYKFLLS 584
Query 604 HGFVVDEKGRKMSKSLGNIITPQDIIKDMGADGLRFWIASSDYRYEMTAGKEIFSRASDG 663
HGFV+D +G+KMSKSLGN+I P ++K GAD R W++S+DY ++ EI + SD
Sbjct 585 HGFVMDGEGKKMSKSLGNVIVPDQVVKQKGADIARLWVSSTDYLSDVRISDEILKKTSDV 644
Query 664 YRRIRNTLRFLLANLNGFTPSTDALPVDQLIALDQYILQRAAEVQKTVQQAYEDMNFHIV 723
YR+IRNTLRF+L N+N F P TD++ L+ +D+Y+L R E + YE+ ++ +
Sbjct 645 YRKIRNTLRFMLGNINDFNPETDSIAETNLLEVDRYLLNRLREFTASTINNYENFDYLNI 704
Query 724 CSALTNFCINDLGGFYLDIIKDRQYTTKADSAARHSAQTALYHLVQAFVRWMSPILSFTA 783
+ NF +L FYLD KD Y K DS R S QT LY ++ + ++PIL TA
Sbjct 705 YQEVQNFINVELSNFYLDYGKDILYIEKKDSHKRRSMQTVLYQILIDMTKLLAPILVHTA 764
Query 784 QEAWPLIPEQTEQYVFTTEWYDIPVASTANLISEADWQTLISVKSAVNKQIEAARNAKLV 843
+E W P E+ V + D+P + W T ++++ VN+ +E ARN K++
Sbjct 765 EEVWSHTPHVKEESVHLS---DMPKVVDVDEELLEKWNTFMNLRDDVNRALEQARNEKVI 821
Query 844 GSNLSAKVEIWAKDELQSV--LNQLGDELRFVLITSQVNV 881
G +L AKV I + + L Q D L+ + I SQV V
Sbjct 822 GKSLEAKVVIGNNETFNTAEFLQQFND-LQQLFIVSQVEV 860
>P41257 Isoleucine--tRNA ligase [Campylobacter jejuni subsp. jejuni
serotype O:2 (strain ATCC 700819 / NCTC 11168)]
Length=917
Score = 620 bits (1598), Expect = 0.0
Identities = 381/928 (41%), Positives = 519/928 (56%), Gaps = 60/928 (6%)
Query 11 VDYKATLNLPGTEFAMKANLAVREVKWLEEWYADNI-YQKIRASRIG-KKKYVLHDGPPY 68
+DYK TL LP T FAM+ANLA E + ++W+ N Y+K++ +R KK + LHDGPPY
Sbjct 1 MDYKETLLLPSTTFAMRANLAELEPQRFKKWFEQNYAYEKMKENRKNAKKSFTLHDGPPY 60
Query 69 ANGQIHLGHAVNKVLKDIIVKSRVMDGFDAPYVPGWDCHGLPIELKVEEKVGKVGVKVDA 128
ANG IH+GHA+NK+LK+ I+K+ G + PGWDCHGLPIE +VE K+G+ +
Sbjct 61 ANGHIHIGHALNKILKETIIKTHYFKGESVRFTPGWDCHGLPIEQQVEVKLGEKKKSLSK 120
Query 129 STFRKACREYALSQVDLQRKDFIRMGVFGDWQDPYLTMNFKQEADIVRSLGEIQKAGHIE 188
R+ CR++A VD+QR++F +G+ DW PYLTM F+ EA I R+L EI K G +
Sbjct 121 KEIREFCRQHASEFVDIQREEFKDLGIIADWDKPYLTMKFEFEAAIYRTLCEIAKKGLLC 180
Query 189 PGLKPVNWCIDCGSALAEAEVEYEDKKSDAIDVGFGVVDLNDLSARLNVEVQDPTDIVIW 248
KPV W SALAEAEVEY+DK+ +I V F + D+ A + V VIW
Sbjct 181 ERSKPVFWSWAAKSALAEAEVEYQDKEDYSIFVAFDL----DVKACEKLGV-SKASAVIW 235
Query 249 TTTPWTLPANQAVALHAEIDYQLVQVQSDRGTQNFILAKDLVESAIARYKLENPVVLADF 308
TTTPWTL ANQA+AL+ +Y + + + I A L++S + + L + + +
Sbjct 236 TTTPWTLVANQAIALNPNENYVITK-------EGLIFASALLKSMVEK-GLTSGEIQKEL 287
Query 309 KGAVLELLQLQHPLLADRQVPVILGEHVIATSGTGAVHTAPGHGTDDYKVGLIYNLKVDN 368
E L+ +PL + V +I+GEHV+ G+G VHTAPGHG DDY L Y ++V
Sbjct 288 NAKEFEKLEAINPLNGRKSV-LIMGEHVLMDGGSGLVHTAPGHGEDDYYACLKYGIEVLM 346
Query 369 PVGGNGVY---------LPTAPI--FSGEHIYKANPQIIEALGATGRLWAHQPIVHSYPH 417
PV +G Y LP+ + F G HI+KAN +I+E LG +L +HSYP
Sbjct 347 PVDDSGCYDETLRAKGLLPSHLLEEFIGLHIFKANEKILELLGE--KLLHSSKFIHSYPF 404
Query 418 CWRHKTPIIFRATPQWFISMD-----AKGLRECALNAIENDISFVPDWGKNRIESMIEGR 472
CWR P+I+RAT QWFI MD K LRECA + +F P G RI SM+E R
Sbjct 405 CWRTHKPVIYRATKQWFILMDEPKLQGKTLRECAKEQLLK-TTFYPQSGVKRIGSMVENR 463
Query 473 PDWCISRQRTWGVPIPFFVHKDTNELHPRTPELIEEVAQLIEHEGIDAWFNREAKDFIGA 532
PDWCISRQR WG PI FF K+T E+ EL + VA + E G DAW+ E KD I
Sbjct 464 PDWCISRQRDWGTPIAFFRDKNTKEV-IFDDELFDFVAAIFEKHGADAWWEFEIKDLIPT 522
Query 533 D----AEHYNAVRDTLDVWFDSGTTHYAVLRQ--REELTDPADLYLEGSDQHRGWFQSSL 586
+ AE+ V D LDVWFDSG+T AVL + A +YLEGSDQHRGWFQSSL
Sbjct 523 NSKYKAENLEKVYDILDVWFDSGSTFNAVLNSGLYDAGEKRASMYLEGSDQHRGWFQSSL 582
Query 587 LTSIAINERAPYKGLLTHGFVVDEKGRKMSKSLGNIITPQDIIKDMGADGLRFWIASSDY 646
L AINE APY+ +LTHGF DEKG+KMSKS GN+I + + K G + LR WI SDY
Sbjct 583 LVGTAINESAPYESILTHGFTTDEKGQKMSKSKGNVIASEYVAKTYGVEILRLWILLSDY 642
Query 647 RYEMTAGKEIFSRASDGYRRIRNTLRFLLANLNGFTPSTDALPVDQLIALDQYILQRAAE 706
++ I + + YR+IRNT+RFLLAN N L V + +D++IL RA +
Sbjct 643 SSDLKISDNILKQVGEQYRKIRNTIRFLLANTNDLKD----LEVKEFSFIDKWILSRATK 698
Query 707 VQKTVQQAYEDMNFHIVCSALTNFCINDLGGFYLDIIKDRQYTTKADSAARHSAQTALYH 766
V K ++A+ F S L NF DL G YLDI KDR Y ++ R SAQ A+
Sbjct 699 VFKASKEAFFAYEFAKGFSLLLNFLSADLSGIYLDISKDRLYCDSENAQRRKSAQVAMAL 758
Query 767 LVQAFVRWMSPILSFTAQEAWPLIPEQTEQYV--FTTEWYDIPVASTANLISEADWQTLI 824
+ + + ++P LS++ EA E + + +D+ + + D L+
Sbjct 759 MAKELLNLLAPNLSYSVDEAL----EHANVLIKGDAKDVFDLSLTQDFDYDFGIDDTFLM 814
Query 825 SVKSAVNKQIEAARNAKLVGSNLSAKVEIWAKDELQSVLNQLGDELRFVLITSQVNVYPY 884
S + +QI+ + K++ S L + I S +EL + SQ++
Sbjct 815 SAREKFFEQIDILKKDKIIKSTLELNLNI-------SFNKFPNEELADWFMVSQIS-NEN 866
Query 885 AEQGESTEMDGLRVQISAAEGEKCVRCW 912
E E++ + +I+ A KC RCW
Sbjct 867 EEILAEFEVENEKFKITKASLCKCPRCW 894
>Q9NSE4 Isoleucine--tRNA ligase, mitochondrial [Homo sapiens]
Length=1012
Score = 542 bits (1397), Expect = 1e-180
Identities = 342/991 (35%), Positives = 502/991 (51%), Gaps = 83/991 (8%)
Query 2 SDKQTPENAVDYKATLNLPGTEFAMK--------ANLAVREVKWLEEWYADNIYQKIRAS 53
S+ Q N+ Y+ T+ LP T F MK L +++ E Y+ +K+
Sbjct 49 SNHQPNSNSGRYRDTVLLPQTSFPMKLLGRQQPDTELEIQQKCGFSELYSWQRERKV--- 105
Query 54 RIGKKKYVLHDGPPYANGQIHLGHAVNKVLKDIIVKSRVMDGFDAPYVPGWDCHGLPIEL 113
K ++ LHDGPPYANG H+GHA+NK+LKDI + +M+G +VPGWDCHGLPIE+
Sbjct 106 ---KTEFCLHDGPPYANGDPHVGHALNKILKDIANRFHMMNGSKIHFVPGWDCHGLPIEI 162
Query 114 KVEEKVGKVGVKVDASTFRKACREYALSQVDLQRKDFIRMGVFGDWQDPYLTMNFKQEAD 173
KV ++G+ + A RK R +A + ++ Q+ FIR G+ DW + Y T + K EA
Sbjct 163 KVLSELGREAQNLSAMEIRKKARSFAKAAIEKQKSAFIRWGIMADWNNCYYTFDGKYEAK 222
Query 174 IVRSLGEIQKAGHIEPGLKPVNWCIDCGSALAEAEVEYE-DKKSDAIDVGFGVVDLNDLS 232
+R+ ++ G + KPV W +ALAEAE+EY + S +I V F ++ +
Sbjct 223 QLRTFYQMYDKGLVYRSYKPVFWSPSSRTALAEAELEYNPEHVSRSIYVKFPLLKPSPKL 282
Query 233 ARLNVEVQDPTDIVIWTTTPWTLPANQAVALHAEIDYQLVQVQSDRGTQNFILAKDLVES 292
A L ++ P I++WTT PWT+PAN+AV E Y + V+ + ++LA D V S
Sbjct 283 ASL-IDGSSPVSILVWTTQPWTIPANEAVCYMPESKYAV--VKCSKSGDLYVLAADKVAS 339
Query 293 AIARYKLENPVVLADFKGAVLELLQLQHPLLADRQVPVILGEHVIATSGTGAVHTAPGHG 352
+ + + + G LE HPL+ D+ P++ HV GTG VHTAP HG
Sbjct 340 VASTLETTFETI-STLSGVDLENGTCSHPLIPDKASPLLPANHVTMAKGTGLVHTAPAHG 398
Query 353 TDDYKVGLIYNLKVDNPVGGNGVYLPTA-PIFSGEHIYKANPQ-IIEALGATGRLWAHQP 410
+DY V +NL +D V +GV+ A P + + + +I+ L L +
Sbjct 399 MEDYGVASQHNLPMDCLVDEDGVFTDVAGPELQNKAVLEEGTDVVIKMLQTAKNLLKEEK 458
Query 411 IVHSYPHCWRHKTPIIFRATPQWFISM-DAKGLRECALNAIENDISFVPDWGKNRIESMI 469
+VHSYP+ WR K P++ RA+ QWFI++ D K A + + F+P N + M+
Sbjct 459 LVHSYPYDWRTKKPVVIRASKQWFINITDIK----TAAKELLKKVKFIPGSALNGMVEMM 514
Query 470 EGRPDWCISRQRTWGVPIPFFVHKDTNELHPRTPELIEEVAQLIEHEGIDAWFNREAKDF 529
+ RP WCISRQR WGVPIP F HK T + + + E + +L+E G D W+ +
Sbjct 515 DRRPYWCISRQRVWGVPIPVFHHK-TKDEYLINSQTTEHIVKLVEQHGSDIWWTLPPEQL 573
Query 530 I---------GADAEHYNAVRDTLDVWFDSGTTHYAVLRQREELTDPADLYLEGSDQHRG 580
+ G DA Y +D LD+WFDSGT+ VL ++ ADLYLEG DQ G
Sbjct 574 LPKEVLSEVGGPDALEYVPGQDILDIWFDSGTSWSYVLPGPDQ---RADLYLEGKDQLGG 630
Query 581 WFQSSLLTSIAINERAPYKGLLTHGFVVDEKGRKMSKSLGNIITPQDIIK---------D 631
WFQSSLLTS+A +RAPYK ++ HGF + EKG KMSKSLGN+I P ++
Sbjct 631 WFQSSLLTSVAARKRAPYKTVIVHGFTLGEKGEKMSKSLGNVIHPDVVVNGGQDQSKEPP 690
Query 632 MGADGLRFWIASSDYRYEMTAGKEIFSRASDGYRRIRNTLRFLLANLNGFTPSTDALPVD 691
GAD LR+W+A S+ E+ G + + A D ++RNTLRFLL N+ F P TD++PV+
Sbjct 691 YGADVLRWWVADSNVFTEVAIGPSVLNAARDDISKLRNTLRFLLGNVADFNPETDSIPVN 750
Query 692 QLIALDQYILQRAAEVQKTVQQAYEDMNFHIVCSALTNFCINDLGGFYLDIIKDRQYTTK 751
+ +DQY+L ++ + + Y+ +F V L F +L FY IIKDR Y K
Sbjct 751 DMYVIDQYMLHLLQDLANKITELYKQYDFGKVVRLLRTFYTRELSNFYFSIIKDRLYCEK 810
Query 752 ADSAARHSAQTALYHLVQAFVRWMSPILSFTAQEAWPLIPEQTE-QYVFTTEWYDIPVAS 810
+ R S QTAL ++ VR +PIL A+E + IP E + VF T W S
Sbjct 811 ENDPKRRSCQTALVEILDVIVRSFAPILPHLAEEVFQHIPYIKEPKSVFRTGW-----IS 865
Query 811 TANLISEADWQTLISVKSAV---------NKQIEAARNAKLVGSNLSAKVEIWAKDELQS 861
T+++ + + + A+ K + ++ L ++ + E S
Sbjct 866 TSSIWKKPGLEEAVESACAMRDSFLGSIPGKNAAEYKVITVIEPGLLFEIIEMLQSEETS 925
Query 862 VLNQLGD---------------ELRFVLITSQVNVYPYAEQGESTEMDGLRVQISAAEGE 906
+QL + E+ +I + E G+ E +V + E
Sbjct 926 STSQLNELMMASESTLLAQEPREMTADVIELKGKFLINLEGGDIREESSYKVIVMPTTKE 985
Query 907 KCVRCWHVLPDVNTHADHPGLCGRCIINVTG 937
KC RCW T LC RC V+G
Sbjct 986 KCPRCWKY-----TAESSDTLCPRCAEVVSG 1011
>P46214 Isoleucine--tRNA ligase [Pyrococcus furiosus (strain ATCC
43587 / DSM 3638 / JCM 8422 / Vc1)]
Length=1066
Score = 432 bits (1110), Expect = 5e-138
Identities = 276/806 (34%), Positives = 417/806 (52%), Gaps = 73/806 (9%)
Query 34 EVKWLEEWYADNIYQKIRASRIGKKKYVLHDGPPYANGQIHLGHAVNKVLKDIIVKSRVM 93
E K + W NIYQK++ R KY DGPPY +G IHLG A NK++KD+I++ R M
Sbjct 16 EEKIEQFWKESNIYQKVKELRKNGPKYYFLDGPPYVSGAIHLGTAWNKIIKDMIIRFRTM 75
Query 94 DGFDAPYVPGWDCHGLPIELKVEEKVG-----KVGVKVDASTFRKACREYALSQVDLQRK 148
G++ PG+D HGLPIE+KVE+ +G ++ K+ F + C+E+AL+ + + +
Sbjct 76 QGYNVWRQPGYDMHGLPIEVKVEQALGLKTKKEIEEKIGVENFIQKCKEFALNNLRIMTE 135
Query 149 DFIRMGVFGDWQDPYLTMNFKQEADIVRSLGEIQKAGHIEPGLKPVNWCIDCGSALAEAE 208
F +GV+ DW +PY+T+ + +L + G +E + ++WC C +ALAE E
Sbjct 136 QFKMLGVWMDWDNPYMTIKNEYIESAWFTLKRAWEKGLLEKDKRVLHWCPRCETALAEHE 195
Query 209 V--EYEDKKSDAIDVGFGVVDLNDLSARLNVEVQDPTDIVIWTTTPWTLPANQAVALHAE 266
V EY+ +K +I V F VE ++ ++IWTTTPWTLPAN AV+ H +
Sbjct 196 VRGEYKLRKDPSIYVKF------------PVEGKENEYLLIWTTTPWTLPANLAVSAHPD 243
Query 267 IDYQLVQVQSDRGTQNFILAKDLVESAIARYKLENPVVLADFKGAVLELLQLQHPLLAD- 325
DY V+V + + +ILAK LVE + ++ VV +FKG LE L+ H L+ +
Sbjct 244 YDYVKVRVDLNGREEYWILAKALVEKVLGDIGVKGEVV-EEFKGKELEGLRYVHILMDEY 302
Query 326 -RQVP----------VILGEHVIATSGTGAVHTAPGHGTDDYKVGLIYNLKVDNPVGGNG 374
RQ VIL + V GTG VHTAPGHG +D++VG Y L V +PV G
Sbjct 303 PRQKEFREKYEWVHRVILADFVTLEEGTGLVHTAPGHGEEDFEVGQKYGLPVYSPVDDQG 362
Query 375 VYLPTAPIFSGEHIYKANPQIIEALGATGRLWAHQPIVHSYPHCWRHKTPIIFRATPQWF 434
Y+ + G ++ +A+PQIIE L G L I H YPHCWR KTP+IFRAT QWF
Sbjct 363 KYVEGK--WKGVYVKEADPQIIEHLKEKGYLVKAGEIEHKYPHCWRCKTPLIFRATDQWF 420
Query 435 ISMDAKGLRECALNAIENDISFVPDWGKNRIESMIEGRPDWCISRQRTWGVPIPFFVHKD 494
+ + ++E + + +++ P+W K R ++ + DW ISRQR WG+P+P + +D
Sbjct 421 LKVSK--VKEKIIKENDEKVTWYPEWVKIRFDNGVRDSGDWVISRQRYWGIPLPIWQSED 478
Query 495 --------------------TNELHPRTPELIEEVAQLIEHEGIDAWFNREAKD--FIGA 532
N PE EE ++IE + +R D I
Sbjct 479 GEIYVVGSWKELVELAVAIEVNGERIDLPESYEEKLKVIEEKLGPEDLHRPYVDAFIIKV 538
Query 533 DAEHYNAVRDTLDVWFDSGTTHYAVL---RQRE--ELTDPADLYLEGSDQHRGWFQSSLL 587
+ + V+D +DVWFDSG +A L R +E E PAD +EG DQ WF S
Sbjct 539 NGKEMRRVKDVVDVWFDSGIASWASLGYPRNKELFEKLWPADFIVEGEDQVTKWFYSQQA 598
Query 588 TSIAINERAPYKGLLTHGFVVDEKGRKMSKSLGNIITPQDIIKDMGADGLRFWIASSDYR 647
S+ + PY+ + HG+V+DEKG KMSKSLGNII P+++++ G D RF++ +
Sbjct 599 ASVIAFDTVPYRAVAMHGYVLDEKGDKMSKSLGNIIRPEEVVEKAGRDTFRFYMLWATNP 658
Query 648 YEMTAGKEIFSRASDGYRRIRN------TLRFLLANLNGFTPSTDALPVDQLIALDQYIL 701
+E + + + RR+ N L +L+ F P + + D++IL
Sbjct 659 WE---NLKFSWKGVEQVRRMLNILWNVYVLSATYMSLDNFDPRNVKVEELEFREEDKWIL 715
Query 702 QRAAEVQKTVQQAYEDMNFHIVCSALTNFCINDLGGFYLDIIKDRQYTTKADSAARHSAQ 761
R + K V+ E AL NF + DL +Y+ +I+ R + + D + +A
Sbjct 716 SRVNNLIKEVENGIETFYLTKATRALYNFVVEDLSRWYVRLIRKRLW-VEGDDPDKLAAY 774
Query 762 TALYHLVQAFVRWMSPILSFTAQEAW 787
L+ + +R M+P + +E +
Sbjct 775 YTLWKVFDVLLRLMAPFTPYITEEIY 800
>P26499 Isoleucine--tRNA ligase [Methanothermobacter marburgensis
(strain ATCC BAA-927 / DSM 2133 / JCM 14651 / NBRC 100331
/ OCM 82 / Marburg)]
Length=1045
Score = 429 bits (1102), Expect = 5e-137
Identities = 271/786 (34%), Positives = 412/786 (52%), Gaps = 63/786 (8%)
Query 32 VREVKWLEEWYADNIYQKIRASRIGKKKYVLHDGPPYANGQIHLGHAVNKVLKDIIVKSR 91
V E K W +IY++++ R +Y DGPPY +G+IHLG A NK++KD ++ +
Sbjct 14 VIEEKVQSFWEERDIYERVKELREEGPRYSFLDGPPYCSGRIHLGTAWNKIMKDSYLRFK 73
Query 92 VMDGFDAPYVPGWDCHGLPIELKVEEKVG-----KVGVKVDASTFRKACREYALSQVDLQ 146
M GF+ PGWD HGLPIE KVE +G + K+ F + CRE+A+ +
Sbjct 74 SMRGFNVRRQPGWDTHGLPIEHKVEGILGVRSKKDIEDKIGIEEFVRKCREFAMENKAVM 133
Query 147 RKDFIRMGVFGDWQDPYLTMNFKQEADIVRSLGEIQKAGHIEPGLKPVNWCIDCGSALAE 206
F R+GV+ DW DPY+T + +L + + L+ + WC C +ALA
Sbjct 134 TSQFQRLGVWMDWDDPYVTFDPAYMESCWWTLKRAHEKDLLLRDLRVITWCPRCETALAL 193
Query 207 AEVEYEDKKSDAIDVGFGVVDLNDLSARLNVEVQDPTDIVIWTTTPWTLPANQAVALHAE 266
AE++Y +K+ +I V F V T I++WTTTPWTLPAN AVA+H +
Sbjct 194 AEIDYHEKEDPSIYVKF--------------PVSGDTYILVWTTTPWTLPANMAVAVHPD 239
Query 267 IDYQLVQVQSDRGTQNFILAKDLVESAIARYKLENPVVLADFKGAVLELLQLQHPLLADR 326
DY ++ + +I+A+ LVE + E ++ +G+ LE L +HPL D
Sbjct 240 FDYAHTRLDGE----TYIMAEALVEKVLG----EEAEIIKTVRGSELEGLTYRHPL--DE 289
Query 327 QVP--------VILGEHVIATSGTGAVHTAPGHGTDDYKVGLIYNLKVDNPVGGNGVYLP 378
+VP VILG+HV T GTG VHTAPGHG +D+++G Y L V PV GV+
Sbjct 290 EVPCHRDMEHRVILGDHVTLTEGTGCVHTAPGHGPEDFEIGKEYGLPVFCPVDEAGVFTE 349
Query 379 TAPIFSGEHIYKANPQIIEALGATGRLWAHQPIVHSYPHCWRHKTPIIFRATPQWFISMD 438
A + G + A+ II+ L + L + I H Y CWR KTPII+ AT QWF+ +
Sbjct 350 DAGKYRGLFVKDADSDIIDDLRSKNLLLRAETISHRYGFCWRCKTPIIYLATEQWFLKIT 409
Query 439 AKGLRECALNAIENDISFVPDW-GKNRIESMIEGRPDWCISRQRTWGVPIPFFVHKDTNE 497
+++ L+ ++ + ++P W G++R + IE DW ISRQR WG+PIP +V +D +
Sbjct 410 E--IKDKMLSELDR-VQWIPSWAGESRFRNWIENARDWTISRQRYWGIPIPIWVCEDCDS 466
Query 498 LHPRTPELIEEVAQL-IEHEGIDAWFNREAKDFI----GADAEHYNAVRDTLDVWFDSGT 552
+H I E+ +L +E + + +R D I G D LDVW DSG
Sbjct 467 IH--VVGSIGELRELAVEGQLEGDFIHRPHVDRIILECGRCGGRMKRTPDVLDVWIDSGV 524
Query 553 THYAVL---RQREELTD--PADLYLEGSDQHRGWFQSSLLTSIAINERAPYKGLLTHGFV 607
+A L R++E ++ P D EG DQ RGWF S L + + PY+ +L HGF
Sbjct 525 AGWAALHYPREKELFSEWFPYDFITEGHDQTRGWFYSQLGCGVIALDETPYRRVLMHGFT 584
Query 608 VDEKGRKMSKSLGNIITPQDIIKDMGADGLRFWIASSDYRYE-MTAGKEIFSRASDGYRR 666
+DE+GRKMSKSLGN++ P+D+I+ GAD LRF++ ++ +E + + + +
Sbjct 585 LDEEGRKMSKSLGNVVEPEDVIEKYGADVLRFYLLWANKPWEDLKFVWDELKNVNKMFNI 644
Query 667 IRNTLRFLLA--NLNGFTPSTDALPVDQLIALDQYILQRAAEVQKTVQQAYEDMNFHIVC 724
+ N F +L+ F P L D++I+ R V V +A ++++FH
Sbjct 645 LWNVYVFATTYMSLDRFQPGDHELEDLHFRDEDRWIISRVNSVALKVTEALDNLHFHRAT 704
Query 725 SALTNFCINDLGGFYLDIIKDRQYTTKADS---AARHSAQTALYHLVQAFVRWMSPILSF 781
+ +F + DL +Y+ +I+ R + + D AA HS TAL L+ +SPI
Sbjct 705 REIHDFIVEDLSRWYIRLIRSRTWIERDDPDKLAAYHSLYTALKTLIVT----LSPIAPH 760
Query 782 TAQEAW 787
++ +
Sbjct 761 VCEDIY 766
Lambda K H a alpha
0.320 0.136 0.418 0.792 4.96
Gapped
Lambda K H a alpha sigma
0.267 0.0410 0.140 1.90 42.6 43.6
Effective search space used: 15542602
Database: 8aee90b20d0f360036bdd9b7993ce82e.SwissProt.fasta
Posted date: May 9, 2024 8:52 AM
Number of letters in database: 18,942
Number of sequences in database: 20
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Neighboring words threshold: 11
Window for multiple hits: 40
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Data ...
