BLASTP 2.12.0+
Reference: Stephen F. Altschul, Thomas L. Madden, Alejandro A.
Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J.
Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of
protein database search programs", Nucleic Acids Res. 25:3389-3402.
Reference for composition-based statistics: Alejandro A. Schaffer,
L. Aravind, Thomas L. Madden, Sergei Shavirin, John L. Spouge, Yuri
I. Wolf, Eugene V. Koonin, and Stephen F. Altschul (2001),
"Improving the accuracy of PSI-BLAST protein database searches with
composition-based statistics and other refinements", Nucleic Acids
Res. 29:2994-3005.
Database: a56564d4a0fec6986d1a47485f123d18.SwissProt.fasta
10 sequences; 5,168 total letters
Query= ACIAD0089
Length=432
Score E
Sequences producing significant alignments: (Bits) Value
P57415 Probable lipid II flippase MurJ [Buchnera aphidicola subsp... 91.7 3e-23
O67658 Probable lipid II flippase MurJ [Aquifex aeolicus (strain ... 90.1 9e-23
O51750 Probable lipid II flippase MurJ [Borreliella burgdorferi (... 90.1 9e-23
Q89AI1 Probable lipid II flippase MurJ [Buchnera aphidicola subsp... 84.3 7e-21
B4E9G3 Lipid II flippase MurJ [Burkholderia cenocepacia (strain A... 84.0 1e-20
O05467 Probable lipid II flippase MurJ [Rhizobium tropici] 77.0 2e-18
Q8VNZ2 Probable lipid II flippase MurJ [Bdellovibrio bacteriovoru... 74.3 1e-17
Q9ZCW4 Probable lipid II flippase MurJ [Rickettsia prowazekii (st... 72.4 5e-17
P56882 Probable lipid II flippase MurJ [Rhizobium meliloti (strai... 72.4 5e-17
O34238 Probable lipid II flippase MurJ [Vibrio cholerae serotype ... 70.1 3e-16
>P57415 Probable lipid II flippase MurJ [Buchnera aphidicola subsp.
Acyrthosiphon pisum (strain APS)]
Length=511
Score = 91.7 bits (226), Expect = 3e-23
Identities = 111/458 (24%), Positives = 210/458 (46%), Gaps = 56/458 (12%)
Query 1 MYKKLLSSSVLVLLIGIAVSALGFIKEMLVAYHFGTSAAIDVFYLALSVPLYLVSLYG-- 58
+ K L+S S++ L+ I LGF++++L+A FG S D F+++ +P L ++
Sbjct 3 LLKPLISVSLMTLISRI----LGFVRDILIASIFGASMFTDAFFISFKIPNLLRRIFSDG 58
Query 59 --SSINATIMPAYLQAKVQEKHRQFFSELMGLNLLFLLALSFICLVYS----ICLQPFFL 112
S ++ Y K ++ + F S ++G FLL L+ + +S + P FL
Sbjct 59 TFSQAFIPVLMEYKSDKNEKNIKNFLSSILGFMSFFLLLLTILGGFFSQSIILIRAPGFL 118
Query 113 HGSAVQNQQVLWIGLL--LCPMIVLQGLTSYFDSILNAEKRNLINNLFSLGIPLGTIILL 170
+ + +L LL + P I+L L+S SILN+ N FS IP + I L
Sbjct 119 N---PPEKLILSTNLLRIMFPYILLISLSSLCSSILNSW------NYFS--IPAFSPIFL 167
Query 171 GFNQIPAALLLTLGWYFGFLLRFLGQYVILKRQIGFCWQAPKRIFFKKYQKLIQDFFW-- 228
+ I ++ + +F + L VI+ + +Q P +K ++ +F W
Sbjct 168 NISIIFFSVFFSS--FFCPSIIVLAWSVIIGGLVQLLYQLP--FLYKINMLVLPNFHWNN 223
Query 229 -------IVFSSAILG-----LLPVISNYLAGYLGAGQVASLNYATKLISTGLMLVGIII 276
AILG + +I+ + L +G ++ + YA +LI + ++G+ +
Sbjct 224 IGLLRILKKMGPAILGASANQISLIINTIFSSLLNSGSISWIYYADRLIEFPVGILGVSL 283
Query 277 NSVLFPHIAEQIVKDQAQGIR-EGMRLAAASLLIFGFIMIP----LYYYVEPIVALVFER 331
++VLF +A K+ GI+ E +L L I + +P L++ +P++ ++F+
Sbjct 284 STVLFTSLA----KNYKNGIKLEYKKLLDWGLRISLIVSLPGSVILFFLAKPVIIVLFQY 339
Query 332 GRFTADSTHQVAYILKYLLLYIPFYVPCILLSRLVVSLGISRIFVWGNLISLVLFFMAGW 391
G+FT A +LK + ++ +LS + +I + +L +L+L +
Sbjct 340 GKFTDFDVLMTARVLKLYSCGLISFIFVKILSSAFYACEEIKIPMKASLFTLLLNQLMNP 399
Query 392 YLMVYLQLGIQSLGWALMLVYLVSALYLLMNIMLYRKR 429
+L+ Y Q G AL L +LL++ LY+++
Sbjct 400 FLIFY----FQHAGIALSLSITSWVNFLLLSRKLYQRK 433
>O67658 Probable lipid II flippase MurJ [Aquifex aeolicus (strain
VF5)]
Length=499
Score = 90.1 bits (222), Expect = 9e-23
Identities = 94/436 (22%), Positives = 197/436 (45%), Gaps = 38/436 (9%)
Query 11 LVLLIGIAVSAL-GFIKEMLVAYHFGTSAAIDVFYLALSVPLYLVSLYG-SSINATIMPA 68
L+ +GI +S + G++++ VAY+FG SA D F++A +P ++G NA +P
Sbjct 9 LLFSLGILLSRIFGYVRDATVAYYFGASAVSDAFFIAFRIPNAFRRIFGEGGFNAVFIPF 68
Query 69 YLQAKVQEKHRQFFSELMGLNLLFLLALSFICLVYSICLQPFFLHGSAVQNQ-----QVL 123
Y +A Q + +F + GL + F L++ I L++ + G + + L
Sbjct 69 YGEAVKQNREEEFLRKTFGLLITFSLSVVIIGLLFPEEIISVISPGIKEKETFSYAVEFL 128
Query 124 WIGLLLCPMIVLQGLTSYFDSILNAEKR----NLINNLFSLGIPLGTIIL---LGFNQIP 176
+L P++ +Y +IL + + ++ LF+LG L +IL LG +
Sbjct 129 KFTILYLPLV---SFYAYSMAILLVQGKFFVPSVSQTLFNLGFILSLVILFHTLGHYSLA 185
Query 177 AALLLTLGWYFGFLLRFL-GQYVILKRQIGFCWQAPKRIFFKKYQKLIQDFFWIVFSSAI 235
A+L+ G L + + +++ K ++ + PK ++ + ++ F + + +
Sbjct 186 LAVLI------GGLFQIIPNTFLLFKEKL---LKIPKFSLDREIKTFLKKFLFTLGGFSA 236
Query 236 LGLLPVISNYLAGYLGAGQVASLNYATKLISTGLMLVGIIINSVLFPHIAEQIVKDQAQG 295
L + +LA +L G ++ + YA ++ + L I +++ L ++ + KD+ +
Sbjct 237 NQLSLFVDTFLASFLKVGSISYVYYAARIYLLPISLFSISLSNTLLALVSTK--KDKEKD 294
Query 296 IREGMRLAAASLLIFGFIMIPLYYYVEPIVALVFERGRFTADSTHQVAYILKYLLLYIPF 355
++L + F L++ IV+++++RG F+ + + +L +PF
Sbjct 295 TDTALKLTLMLSIPSSF---GLFFLSREIVSVLYKRGNFSEEDLFYTSGLLSLYAFSVPF 351
Query 356 YVPCILLSRLVVSLGISRIFVWGNLISLVLFFMAGWYLMVYLQLGIQSLGWALMLVYLVS 415
Y +L + S I +S+ L + G + L G+ ++ L L+S
Sbjct 352 YSLQHILKTVYYSKKNVEIPTKSAFLSVFLEALFGSVFIFLLNFGV----YSFPLAALIS 407
Query 416 ALYLLMNIMLYRKRTQ 431
+ +L + LY+K Q
Sbjct 408 SSSVL--VYLYQKLPQ 421
Score = 18.9 bits (37), Expect = 3.9
Identities = 19/84 (23%), Positives = 40/84 (48%), Gaps = 12/84 (14%)
Query 302 LAAASLLIFGF------IMIPLYYYVEPIVALVFERGR-FTADSTHQ-----VAYILKYL 349
++++S+L++ + + IP ++ ++A F G + +S Q V++I Y
Sbjct 406 ISSSSVLVYLYQKLPQKVSIPFGNLIKYLIASSFMGGLVYLTESLTQNPFILVSFIPIYA 465
Query 350 LLYIPFYVPCILLSRLVVSLGISR 373
L Y F + +++S GI R
Sbjct 466 LFYYVFLIILREELAILISYGIFR 489
>O51750 Probable lipid II flippase MurJ [Borreliella burgdorferi
(strain ATCC 35210 / DSM 4680 / CIP 102532 / B31)]
Length=506
Score = 90.1 bits (222), Expect = 9e-23
Identities = 99/432 (23%), Positives = 193/432 (45%), Gaps = 24/432 (6%)
Query 4 KLLSSSVLVLLIGIAVSALGFIKEMLVAYHFGTSAAIDVFYLALSVPLYLVSLYG-SSIN 62
K + S++LV++ +GF+K + +Y+FG + D+F ++P L + ++
Sbjct 3 KYVVSTILVMISTFFSRIMGFVKIKIFSYYFGANLDADIFNYVFNIPNNLRKILSEGAMT 62
Query 63 ATIMPAYL--QAKVQEKHRQFFSELMGLNLLFLLALSFICLVYSICLQPFFLHGSAVQNQ 120
+ +P + + K EK FF ++ N ++++ I LV I +P S + +
Sbjct 63 SAFLPEFTHEKNKSHEKAVSFFRTVITFN---IISIGLIVLVMIIFAKPIMYFISYYRGE 119
Query 121 QVLWIGLL---LCPMIVLQGLTSYFDSILNAEKRNLINN----LFSLGIPLGTIILLGFN 173
+++ + L I+L L+S F S+LN+ K I + + S GI L + G
Sbjct 120 NLIFASSVFGYLVLYILLISLSSIFVSVLNSYKIFFIPSFSPIMLSFGIILSIFLFYGRF 179
Query 174 QIPAALLLTLGWYFGFLLRFLGQYVILKRQIGFCWQAPKRIFFKKYQKLIQDFFWIVFSS 233
I +A+ +G FG L+FL + IGF W+ K + + + ++F
Sbjct 180 GIYSAV---IGVIFGGFLQFLIPFANC-LMIGFAWKPTFYFREKVFLNFLTRWLRMIFGF 235
Query 234 AILGLLPVISNYLAGYLGAGQVASLNYATKLISTGLMLVGIIINSVLFPHIAEQIVKDQA 293
+I + IS LA L G V+ L+ A + + I I +V+FP +AE V
Sbjct 236 SISIITQQISFALASTLEIGSVSILSNAVVYYQLPVGIFYISIATVIFPKMAEHAVLGNN 295
Query 294 QGIR----EGMRLAAASLLIFGFIMIPLYYYVEPIVALVFERGRFTADSTHQVAYILKYL 349
+ +G+++ LLIF + ++ + + I+ L G+F+ T + A +LK
Sbjct 296 IKLNALLVDGIKIL---LLIFIPVSFLMFIWSDYILNLFLMGGKFSIYDTQKTASVLKCF 352
Query 350 LLYIPFYVPCILLSRLVVSLGISRIFVWGNLISLVLFFMAGWYLMVYLQLGIQSLGWALM 409
LL + FY + S+ ++ + +++ +L + + Y L +L ++
Sbjct 353 LLGLLFYSMFGFFQKYYFSIRDAKTPFYLSVLFSILDIAISVFGINYYGLNALALAQSIS 412
Query 410 LVYLVSALYLLM 421
+ V Y ++
Sbjct 413 FMICVIVFYFII 424
Score = 18.9 bits (37), Expect = 3.9
Identities = 22/107 (21%), Positives = 40/107 (37%), Gaps = 18/107 (17%)
Query 302 LAAASLLIFGFIMIPLYYYVEPIVALVFERGRFTADSTHQVAYILKYLLLYIPFYVPCIL 361
LA A + F +I Y+ ++ +RG D + +LK ++ P Y
Sbjct 405 LALAQSISFMICVIVFYF-------IILKRG-VKIDLIEILFVLLKSIITLFPLYAIYFF 456
Query 362 LSRLVVSLGIS----RIFVWGNLISLVLFFMAGWYLMVYLQLGIQSL 404
+ +G S + ++S+ + F+ Y LGI L
Sbjct 457 FEKFQWDVGFSFKNLYFLMAAGIVSIFVLFIC------YSVLGINKL 497
>Q89AI1 Probable lipid II flippase MurJ [Buchnera aphidicola subsp.
Baizongia pistaciae (strain Bp)]
Length=513
Score = 84.3 bits (207), Expect = 7e-21
Identities = 85/380 (22%), Positives = 169/380 (44%), Gaps = 31/380 (8%)
Query 5 LLSSSVLVLLIGIAVSALGFIKEMLVAYHFGTSAAIDVFYLALSVPLYLVSLYG----SS 60
+L S + + LI LGF++++L+AY FG S D F+LA +P ++ S
Sbjct 3 ILKSLISLSLITFISRILGFMRDLLIAYSFGASGITDAFFLAFKIPNLFRRIFAEGAFSQ 62
Query 61 INATIMPAYLQAKVQEKHRQFFSELMGLNLLFL-----LALSFICLVYSICLQPFFLHGS 115
+ I+ Y K E R F S ++GL ++ L + F + IC F
Sbjct 63 VFIPILSEYKNNKNIELTRNFISNILGLMIIILSLFTAFGIYFANDIVKICAPGF----- 117
Query 116 AVQNQQVLWIGL----LLCPMIVLQGLTSYFDSILNAEKRNLINNLFSLGIPLGTIILLG 171
+ + + L++ ++ P I L S SILNA + S+ + L I+ +
Sbjct 118 -INSHEKLYLATKMLKIMFPYIFFVSLGSLTGSILNAWNYFSVPAYSSIFLNLSMIMFIS 176
Query 172 FNQI---PAALLLTLGWYFGFLLRFLGQYVILKRQIGFCWQAPKRIFFKKYQKLIQDFFW 228
F P L L G + + L Q+ LK I I K ++
Sbjct 177 FVTAYFNPKILSLAWAVIVGGVFQILYQFPYLK-NINMLIFPKFNILNLGVLKFLKQIGI 235
Query 229 IVFSSAILGLLPVISNYLAGYLGAGQVASLNYATKLISTGLMLVGIIINSVLFPHIAEQI 288
+ ++ + +I+ + +L +G ++ + Y+ +L+ + G+ ++++L P +++ +
Sbjct 236 VALGMSVNQVSIIIATISSSFLISGSISWIYYSDRLVEFISGIFGVSLSTILLPLLSKSV 295
Query 289 ----VKDQAQGIREGMRLAAASLLIFGFIMIPLYYYVEPIVALVFERGRFTADSTHQVAY 344
+K+ ++ + +RL +L+ I+I L+ E ++ L+F+ G FT +
Sbjct 296 NNINIKEYSRLLNWALRLVC--ILVIPSIII-LFTLSESLITLLFKYGAFTYNDVIMTKN 352
Query 345 ILK-YLLLYIPFYVPCILLS 363
+++ Y + +PF + ILL+
Sbjct 353 VIEFYSIGLLPFVLIKILLA 372
Score = 31.6 bits (70), Expect = 4e-04
Identities = 52/256 (20%), Positives = 106/256 (41%), Gaps = 43/256 (17%)
Query 5 LLSSSVLVLLIGIAVSALGFIKEML------VAYHFGTSAAIDVFYLALSVPLYLVSLYG 58
+L+ VL L I + ALG + ++ F S +I Y + + ++ ++G
Sbjct 221 ILNLGVLKFLKQIGIVALGMSVNQVSIIIATISSSFLISGSISWIYYSDRLVEFISGIFG 280
Query 59 SSINATIMPAYLQAKVQEKHRQFFSELMG--LNLLFLLALSFICLVYSIC---LQPFFLH 113
S++ ++P L V + + +S L+ L L+ +L + I +++++ + F +
Sbjct 281 VSLSTILLPL-LSKSVNNINIKEYSRLLNWALRLVCILVIPSIIILFTLSESLITLLFKY 339
Query 114 GSAVQNQQVLWIGLL------LCPMIVLQGLTSYFDSILNAEKRNLINNLFSLGIPLGTI 167
G+ N ++ ++ L P ++++ L + F SI N + I+ I
Sbjct 340 GAFTYNDVIMTKNVIEFYSIGLLPFVLIKILLAGFYSIRNVKTPMKIS-----------I 388
Query 168 ILLGFNQIPAALLLTLGWYFGFLLRFLGQYVILKRQIGFCWQAPKRIFFKKYQKLIQDFF 227
+L Q+ + Y F L + L I F F Y+KL Q F
Sbjct 389 FILVLTQLMNIFFIKYFQYTSFALA-----ISLASWINF---------FLLYRKLCQSEF 434
Query 228 WIVFSSAILGLLPVIS 243
+I ++ + LL + +
Sbjct 435 FIPSTNWLRFLLKIFA 450
Score = 22.3 bits (46), Expect = 0.32
Identities = 37/166 (22%), Positives = 74/166 (45%), Gaps = 21/166 (13%)
Query 268 GLMLVGIIINSVLFPHIAEQIVKDQAQGI---REGMRLAAASLLIFGFIMIPLYYYVE-- 322
GLM++ + + + + A IVK A G E + LA L I M P ++V
Sbjct 89 GLMIIILSLFTAFGIYFANDIVKICAPGFINSHEKLYLATKMLKI----MFPYIFFVSLG 144
Query 323 PIVALVFERGRFTADSTHQVAYILKYLLLYIPF----YVPCIL-LSRLVVSLGISRI--- 374
+ + + + + ++ ++++I F + P IL L+ V+ G+ +I
Sbjct 145 SLTGSILNAWNYFSVPAYSSIFLNLSMIMFISFVTAYFNPKILSLAWAVIVGGVFQILYQ 204
Query 375 FVWGNLISLVLF----FMAGWYLMVYLQLGIQSLGWALMLVYLVSA 416
F + I++++F + L Q+GI +LG ++ V ++ A
Sbjct 205 FPYLKNINMLIFPKFNILNLGVLKFLKQIGIVALGMSVNQVSIIIA 250
>B4E9G3 Lipid II flippase MurJ [Burkholderia cenocepacia (strain
ATCC BAA-245 / DSM 16553 / LMG 16656 / NCTC 13227 / J2315
/ CF5610)]
Length=516
Score = 84.0 bits (206), Expect = 1e-20
Identities = 109/480 (23%), Positives = 195/480 (41%), Gaps = 75/480 (16%)
Query 1 MYKKLLSSSVLVLLIGIAVSALGFIKEMLVAYHFGTSAAIDVFYLALSVPLYLVSLYGS- 59
+++ LL+ S LL + G +E L+A FG S D FY+A +P L L
Sbjct 3 LFRALLTVSGFTLLSRVT----GLARETLIARAFGASQYTDAFYVAFRIPNLLRRLSAEG 58
Query 60 SINATIMPAYLQAKVQEKHRQFFSELMGLNLLFLLALSFICLV------YSICLQPFFLH 113
+ + +P + K Q+ H + + ++ + AL+ + +V + + LH
Sbjct 59 AFSQAFVPILAEFKNQQGHDATKALVDAMSTVLAWALAVLSVVGIAGASWVVFAVASGLH 118
Query 114 GSAVQNQQVLWIGLLLCPMIVLQGLTSYFDSILNAEKRNLINNLFSLGIPLGTIILLGFN 173
+ + ++ P IV LT+ +LN K S +P +LL
Sbjct 119 SDGQAFPLAVTMTRIMFPYIVFISLTTLASGVLNTYK--------SFSLPAFAPVLLNVA 170
Query 174 QIPAALLLT---------LGW--YFGFLLRFLGQYVILKR--QIGFCWQAPKRIF-FKKY 219
I AA+ + L W G +L+FL Q LK+ + P R
Sbjct 171 FIAAAVFVAPHLKVPVYALAWAVIVGGVLQFLVQLPGLKKVDMVPLIGLNPLRALRHPGV 230
Query 220 QKLIQDFFWIVFSSAILGLLPVISNYLAGYLGAGQVASLNYATKLISTGLMLVGIIINSV 279
++++ F+ ++ L +I+ +A LG G V+ +NYA +L+ L+G+ + ++
Sbjct 231 KRVLAKMVPATFAVSVAQLSLIINTNIASRLGQGAVSWINYADRLMEFPTALLGVALGTI 290
Query 280 LFPHIAEQIVKDQAQ--------GIREGMRLAAASLLIFGFIMIPLYYYVEPIVALVFER 331
L P +++ V + G+R LAA S L L+++ P+ A +F
Sbjct 291 LLPSLSKAHVDADSHEYSALLDWGLRVTFLLAAPSAL-------ALFFFATPLTATLFNY 343
Query 332 GRFTADSTHQVAY-----------ILKYLLLYIPFYVPCILLSRLVVSLGISRIFVWGNL 380
G+F A + VA I+ +L FY + + + +++G+ + N
Sbjct 344 GKFDAHTVTMVARALATYGIGLVGIILIKILAPGFYAKQDIKTPVKIAIGVLIVTQLSNY 403
Query 381 ISLVLFFMAGWYLMV---------YLQLGIQ-------SLGWALMLVYLVSALYLLMNIM 424
+ + L AG L + L LG++ S GW V LV A +L +M
Sbjct 404 VFVPLIGHAGLTLSIGVGACLNSLLLFLGLRKRGIYQPSPGWLRFFVQLVGAALVLAGLM 463
>O05467 Probable lipid II flippase MurJ [Rhizobium tropici]
Length=533
Score = 77.0 bits (188), Expect = 2e-18
Identities = 79/352 (22%), Positives = 153/352 (43%), Gaps = 21/352 (6%)
Query 23 GFIKEMLVAYHFGTSAAIDVFYLALSVPLYLVSLYGS-SINATIMPAY---LQAKVQEKH 78
GF +E L+A GT DVFY A P L+ + NA +P + ++A +
Sbjct 21 GFARETLMAAALGTGPMADVFYAAFRFPNLFRRLFAEGAFNAAFVPLFAKEIEANGIDGA 80
Query 79 RQFFSELMGLNLLFLLALSFIC-----LVYSICLQPFFLHGSAVQNQQVLWIGLLLCPMI 133
++F E+ G+ LL ++ + L+ + P F A + + + ++ P +
Sbjct 81 KRFSEEVFGVLFSVLLLITIVMELAMPLLVRWVIAPGFAD-DAEKFDLTVRLAAVMFPYL 139
Query 134 VLQGLTSYFDSILNAEKRNLINNLFSLGIPLGTIILLGFNQIPAALLLTLGWYFGFLLRF 193
+ LT+ +LN+ + + + L I L + A LT WY + +
Sbjct 140 MSMSLTAMMSGMLNSLHHFFAAAVAPIFLNLVMISALFYAIYFGADPLTTAWYLSWSVLV 199
Query 194 LGQYVILKRQIGFCWQAPK-RIFFKKYQKLIQDFFWIVFSSAILGLLPVISNYLAGYLGA 252
G + IG + F ++ ++ + +AI G + I+ + + +
Sbjct 200 AGVLQLAVVYIGVRHAGISIGLRFPRFTPNVKRLLLLAIPAAITGGVTQINLVIGQAIAS 259
Query 253 GQ---VASLNYATKLISTGLMLVGIIINSVLFPHIAEQIVKDQAQGIREGMRLAAASLLI 309
G+ +A+L YA ++ L +VG+ + VL P +A + ++ I+E + S+
Sbjct 260 GKEGAIAALQYADRIYQLPLGVVGVAVGIVLLPELARSL---KSGHIKEAANIQNRSIEF 316
Query 310 FGFIMIP----LYYYVEPIVALVFERGRFTADSTHQVAYILKYLLLYIPFYV 357
F+ +P L+ + I+ +++ERG F A++T V IL L +P +V
Sbjct 317 VLFLTLPAAVALWLLSDDIIRVLYERGAFNANNTTLVGSILAIFGLGLPAFV 368
Score = 19.2 bits (38), Expect = 2.9
Identities = 15/63 (24%), Positives = 25/63 (40%), Gaps = 14/63 (22%)
Query 1 MYKKLLSSSVLVLLIGIAVSALGF--------------IKEMLVAYHFGTSAAIDVFYLA 46
M+ L+S S+ ++ G+ S F I + A +FG +YL+
Sbjct 135 MFPYLMSMSLTAMMSGMLNSLHHFFAAAVAPIFLNLVMISALFYAIYFGADPLTTAWYLS 194
Query 47 LSV 49
SV
Sbjct 195 WSV 197
>Q8VNZ2 Probable lipid II flippase MurJ [Bdellovibrio bacteriovorus
(strain ATCC 15356 / DSM 50701 / NCIMB 9529 / HD100)]
Length=523
Score = 74.3 bits (181), Expect = 1e-17
Identities = 97/442 (22%), Positives = 193/442 (44%), Gaps = 39/442 (9%)
Query 3 KKLLSSSVLVLLIGIAVSALGFIKEMLVAYHFGTSAAIDVFYLALSVPLYLVSLYGS-SI 61
KK+L S+ L+ + LG +++ + F A D + A +P L+G S+
Sbjct 13 KKVLKSAFLMASGTLTSRILGLFRDIALGALFDR-AVTDAWTAAFRIPNLFRRLFGEGSL 71
Query 62 NATIMPAYLQAKVQE----KHRQFFSELMGLNLLFLLALSFICLVYSICLQPFFLHGS-- 115
+ +P ++Q + ++ + R + L L+FL L+ + +VY L L
Sbjct 72 AVSFIPVFMQTQSEDPTGDRARNLANAFYSLLLVFLGVLTLLGIVYVEPLFRLILSSDYA 131
Query 116 --AVQNQQVLWIGLLLCPMIVLQGLTSYFDSILNAEKRNLINNLFSLGIP-----LGTII 168
A + + L +G ++ + +++ ILNA L S G+P L +
Sbjct 132 LDAAKWELTLRMGRIMFGFVFFVCTYAFYMGILNA--------LGSFGLPALAPALLNVS 183
Query 169 LLGFNQIPAALL------LTLGWYFGFLLRFLGQYVILKRQIGFCWQAPKRIFFKKYQKL 222
+L F +P L G G LL+ L V LK++ + + K ++ + + +
Sbjct 184 MLVFTFMPPQWFAVHGDGLAWGVLIGGLLQALLLAVALKQR-NYLPRLQKTLWTPEVKAV 242
Query 223 IQDFFWIVFSSAILGLLPVISNYLAGYLGAGQVASLNYATKLISTGLMLVGIIINSVLFP 282
++ + +L +++ Y A L G ++ + +A +L+ L L+ + I + L P
Sbjct 243 VRGMLPGLIGMGLLQFSTLVNLYFASSLPEGSISYIYWADRLLELPLSLISVSIGAALLP 302
Query 283 HIAEQIVKDQAQGIREGMRLAAASLLIFGFIMIP----LYYYVEPIVALVFERGRFTADS 338
+++ + + +E A S L+ F+ P LY EPI+ ++F RG+FT
Sbjct 303 TLSDFANRGLKEKFQE---TAEESFLMNLFLAWPAALGLYILAEPIIEVLFLRGKFTVQD 359
Query 339 THQVAYILKYLLLYIPFYVPCILLSRLVVSLGISRIFVWGNLISLVLFFMAGWYLMVYLQ 398
A IL+ + + +L L S+ +++ + L+SL + LM Q
Sbjct 360 VQMTAAILRIYAVSLLLVSCSRVLMPLYYSVKNTKVPMVLALVSLAVHVSLAPVLM--RQ 417
Query 399 LGIQSLGWALMLVYLVSALYLL 420
G++ L + ++ L++A+ L+
Sbjct 418 WGLEGLMISGVVAALINAVLLM 439
>Q9ZCW4 Probable lipid II flippase MurJ [Rickettsia prowazekii
(strain Madrid E)]
Length=507
Score = 72.4 bits (176), Expect = 5e-17
Identities = 90/437 (21%), Positives = 194/437 (44%), Gaps = 39/437 (9%)
Query 5 LLSSSVLVLLIGIAVSALGFIKEMLVAYHFGTSAAIDVFYLALSVPLYLVSLYGS-SINA 63
L S +++ + G ++E +A FG++ D +A +P ++ ++++
Sbjct 3 LFRSGIILAFLTFIARIFGLVREQFIASLFGSTPMGDSMNIAFKLPNLFRRIFAEGALSS 62
Query 64 TIMPAYLQAK-VQEKHRQFFS----ELMGLNLLFLLALSFICLVYSI-CLQPFFLHGSAV 117
+P Y + + +K FS L+ L L+ ++AL I + I C+ P F +
Sbjct 63 VFIPIYNEKMLISKKAANNFSGKVFTLLSLTLIVIIALMQIFMPQLILCIAPGF-YAKKE 121
Query 118 QNQQVLWIGLLLCPMIVLQGLTSYFDSILNAEKRNLINNLFSLGIPLGTII--LLGFNQI 175
+ + +++ + P ++ LT+ ILN+ K+ + + + II L+ N I
Sbjct 122 KFELTVFLCRITIPYLIFVSLTALLGGILNSVKKFAAFAFSPIILSVCVIIFTLIFGNYI 181
Query 176 PAALLLTLGWYFGFLLRFLGQYVILKRQ-----IGFCWQAPKRIFFKKYQKLIQDFFWIV 230
+ + +++ +L+ + ++ +K+ I F P +KL+ +
Sbjct 182 ESTISISVSLIIAGILQVVFMFICVKKADLHFPIIFHTNDPD------VKKLLINMGPAT 235
Query 231 FSSAILGLLPVISNYLAGYLGAGQVASLNYATKLISTGLMLVGIIINSVLFPHIAE---- 286
SS + L IS ++ ++ G ++ L YA ++ L ++G +++L P +++
Sbjct 236 ISSGVQQLNLFISQSISSFI-EGAISILAYADRIYQFPLSIIGTSFSTILLPEMSKVYKS 294
Query 287 ----QIVKDQAQGIREGMRLAAASLLIFGFIMIPLYYYVEPIVALVFERGRFTADSTHQV 342
K Q IR G+ L+ + FG I++ PI +++ERG FT T
Sbjct 295 NDIVSAQKIQNNAIRIGLLLSLPAT--FGIIILS-----HPITNIIYERGVFTPQDTTNT 347
Query 343 AYILKYLLLYIPFYVPCILLSRLVVSLGISRIFVWGNLISLVLFFMAGWYLMVYLQ-LGI 401
A + L +P ++ +L+ + + G ++ + L S+++ LM L+ +GI
Sbjct 348 AEAISAFALGLPAFILAKILTPIFYANGDTKTPLKITLFSIIINTNMNLLLMDSLKHIGI 407
Query 402 QSLGWALMLVYLVSALY 418
++G ++ Y + LY
Sbjct 408 -AVGTSIAAWYNLGLLY 423
>P56882 Probable lipid II flippase MurJ [Rhizobium meliloti (strain
1021)]
Length=535
Score = 72.4 bits (176), Expect = 5e-17
Identities = 89/361 (25%), Positives = 153/361 (42%), Gaps = 39/361 (11%)
Query 23 GFIKEMLVAYHFGTSAAIDVFYLALSVPLYLVSLYGS-SINATIMPAY---LQAKVQEKH 78
GFI+E +A GT D F A +P L+ + N+ +P + ++A +
Sbjct 21 GFIRETFMAAALGTGPVADAFNTAFRLPNTFRRLFAEGAFNSAFVPLFAKEIEAHGMDGA 80
Query 79 RQFFSELMGLNLLFLLALSFIC-----LVYSICLQPFFLHGSAVQNQQVLWIGLLLCPMI 133
R+F E+ G+ LL L+ + + P F A V + ++ P +
Sbjct 81 RRFSEEVFGVLFTVLLLLTIAMELSMPFIVGQLIAPGFADDPAKFTSTVTFATIMF-PYL 139
Query 134 VLQGLTSYFDSILNAEKRNLINNLFSLGIPLGTIILLGF----NQIPAALLLTLGWYFGF 189
L + +LN+ R + + + I +L + Q A+ L W G
Sbjct 140 ACMSLAAMMAGMLNSLHRYFAAAIAPVFLNFILIAVLAYAWYSGQDAVAVGYDLSW--GV 197
Query 190 LLRFLGQYVILKRQIGFCWQAPK----RIFFKKYQKL--IQDFFWIVFSSAILGLLPVIS 243
L L Q I+ W A + RI F++ + ++ + +AI G + I+
Sbjct 198 LAAGLVQLAIV-------WVAVRNAGIRIGFRRPRLTPNVKRLLVLALPAAITGGITQIN 250
Query 244 NYLAGYLGA---GQVASLNYATKLISTGLMLVGIIINSVLFPHIAEQIVKDQAQGIREGM 300
+ + + G V+SL YA ++ L +VGI + +VL P +A + + + E
Sbjct 251 LLINTNIASAKEGAVSSLVYADRIYQLPLGVVGIAVATVLLPELARAL---RGGNLNEAA 307
Query 301 RLAAASLLIFGFIMIP----LYYYVEPIVALVFERGRFTADSTHQVAYILKYLLLYIPFY 356
L S+ F+ +P L EPIV L+FERG+F+ +ST V +IL L +P +
Sbjct 308 NLQNRSVEFTLFLTLPAAAALLVMSEPIVRLLFERGQFSPESTVVVGHILAIYGLGLPAF 367
Query 357 V 357
V
Sbjct 368 V 368
>O34238 Probable lipid II flippase MurJ [Vibrio cholerae serotype
O1 (strain ATCC 39315 / El Tor Inaba N16961)]
Length=525
Score = 70.1 bits (170), Expect = 3e-16
Identities = 83/369 (22%), Positives = 159/369 (43%), Gaps = 33/369 (9%)
Query 3 KKLLSSSVLVLLIGIAVSALGFIKEMLVAYHFGTSAAIDVFYLALSVPLYLVSLYG---- 58
K+LL S ++V + + LG +++++VA G A+ DVF+ A +P +L L+
Sbjct 8 KRLLKSGIIVSAMTLISRVLGLVRDVVVANLMGAGASADVFFFANRIPNFLRRLFAEGAF 67
Query 59 SSINATIMPAYLQAKVQEKHRQFFSELMGLNLLFLLALSFICLVYSICLQPFF------- 111
S ++ Y + K R + G + + ++ I ++ S + F
Sbjct 68 SQAFVPVLTEYHASGDINKTRDLIARASGTLGVLVTIVTLIGVLGSGAVTALFGAGWFLD 127
Query 112 -LHGSAVQNQQVLWIGLLLCPMIVLQGLT--SYFDSILNAEKRNLINNLFSLGIPLGTII 168
L+G + L LL L +T + +ILN + +++ + + + I+
Sbjct 128 WLNGGPAAGKFELASLLLKITFPYLWFITFVALSGAILNTLGKFAVSSFTPVFLNVMMIL 187
Query 169 ---LLGFNQIPAALLLTLGWYFGFLLRFLGQY-------VILKRQIGFCWQAPKRIFFKK 218
L N + L +G + G L++FL Q V+++ + G W+ P + K
Sbjct 188 CAWYLSPNLEQPEVGLAIGVFLGGLVQFLFQLPFLIKAGVLVRPKWG--WKDPGVV--KI 243
Query 219 YQKLIQDFFWIVFSSAILGLLPVISNYLAGYLGAGQVASLNYATKLISTGLMLVGIIINS 278
+I F + S L + +++A +L G ++ L Y+ +L+ L L GI I +
Sbjct 244 RTLMIPALFGVSVSQINL----LFDSFVASFLQTGSISWLYYSDRLLEFPLGLFGIAIAT 299
Query 279 VLFPHIAEQIVKDQAQGIREGMRLAAASLLIFGF-IMIPLYYYVEPIVALVFERGRFTAD 337
V+ P ++ + V + G M + G M+ L +P++ ++F RG FT
Sbjct 300 VILPALSRKHVDAHSDGFAHTMDWGIRMVTFLGIPAMLGLMVLAKPMLMVLFMRGEFTPS 359
Query 338 STHQVAYIL 346
Q +Y L
Sbjct 360 DVEQASYSL 368
Score = 24.3 bits (51), Expect = 0.082
Identities = 40/198 (20%), Positives = 72/198 (36%), Gaps = 12/198 (6%)
Query 233 SAILGLLPVISNYLAGYLGAGQVASLNYATKLISTGL--MLVGIIINSVLFPHIAEQIVK 290
S +LGL+ + +A +GAG A + + I L + + P + E
Sbjct 24 SRVLGLVRDV--VVANLMGAGASADVFFFANRIPNFLRRLFAEGAFSQAFVPVLTEYHAS 81
Query 291 DQAQGIREGMRLAAASLLIFGFIMIPLYYYVEPIVALVFERGRF--------TADSTHQV 342
R+ + A+ +L + I+ + V +F G F A
Sbjct 82 GDINKTRDLIARASGTLGVLVTIVTLIGVLGSGAVTALFGAGWFLDWLNGGPAAGKFELA 141
Query 343 AYILKYLLLYIPFYVPCILLSRLVVSLGISRIFVWGNLISLVLFFMAGWYLMVYLQLGIQ 402
+ +LK Y+ F L ++ +LG + + + V+ + WYL L+
Sbjct 142 SLLLKITFPYLWFITFVALSGAILNTLGKFAVSSFTPVFLNVMMILCAWYLSPNLEQPEV 201
Query 403 SLGWALMLVYLVSALYLL 420
L + L LV L+ L
Sbjct 202 GLAIGVFLGGLVQFLFQL 219
Lambda K H a alpha
0.334 0.148 0.448 0.792 4.96
Gapped
Lambda K H a alpha sigma
0.267 0.0410 0.140 1.90 42.6 43.6
Effective search space used: 1791674
Database: a56564d4a0fec6986d1a47485f123d18.SwissProt.fasta
Posted date: May 9, 2024 1:51 AM
Number of letters in database: 5,168
Number of sequences in database: 10
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Neighboring words threshold: 11
Window for multiple hits: 40
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Data ...
