BLASTP 2.12.0+
Reference: Stephen F. Altschul, Thomas L. Madden, Alejandro A.
Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J.
Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of
protein database search programs", Nucleic Acids Res. 25:3389-3402.
Reference for composition-based statistics: Alejandro A. Schaffer,
L. Aravind, Thomas L. Madden, Sergei Shavirin, John L. Spouge, Yuri
I. Wolf, Eugene V. Koonin, and Stephen F. Altschul (2001),
"Improving the accuracy of PSI-BLAST protein database searches with
composition-based statistics and other refinements", Nucleic Acids
Res. 29:2994-3005.
Database: a102b2436838460a35fb70a1b315d9d8.SwissProt.fasta
13 sequences; 5,294 total letters
Query= ACIAD0112
Length=405
Score E
Sequences producing significant alignments: (Bits) Value
P04693 Aromatic-amino-acid aminotransferase [Escherichia coli (st... 508 0.0
P74861 Aromatic-amino-acid aminotransferase [Salmonella typhimuri... 506 0.0
O85746 Tyrosine aminotransferase [Klebsiella pneumoniae] 497 7e-180
P72173 Aspartate aminotransferase [Pseudomonas aeruginosa (strain... 398 1e-140
P44425 Aspartate aminotransferase [Haemophilus influenzae (strain... 360 4e-126
Q56114 Aspartate aminotransferase [Salmonella typhi] 323 3e-111
P58661 Aspartate aminotransferase [Salmonella typhimurium (strain... 322 5e-111
P00506 Aspartate aminotransferase, mitochondrial [Sus scrofa] 317 1e-108
P12344 Aspartate aminotransferase, mitochondrial [Bos taurus] 317 1e-108
P00509 Aspartate aminotransferase [Escherichia coli (strain K12)] 315 3e-108
P08907 Aspartate aminotransferase, mitochondrial [Equus caballus] 313 2e-107
P05202 Aspartate aminotransferase, mitochondrial [Mus musculus] 313 5e-107
P00505 Aspartate aminotransferase, mitochondrial [Homo sapiens] 313 5e-107
>P04693 Aromatic-amino-acid aminotransferase [Escherichia coli
(strain K12)]
Length=397
Score = 508 bits (1307), Expect = 0.0
Identities = 255/397 (64%), Positives = 300/397 (76%), Gaps = 0/397 (0%)
Query 1 MFQHIPPYAGDPILSLMEQFNADSREAKVNLSIGLYYNEDSIVPQLDSVIEAQKRIEPRQ 60
MFQ + YAGDPIL+LME+F D R KVNLSIGLYYNED I+PQL +V EA+ R+ +
Sbjct 1 MFQKVDAYAGDPILTLMERFKEDPRSDKVNLSIGLYYNEDGIIPQLQAVAEAEARLNAQP 60
Query 61 NKVKPYLPMEGFKPYRDAIQTLLFGHNSPAVKAGRAVTIQTLGGSGALKVGADFLKNYFP 120
+ YLPMEG YR AI LLFG + P +K R TIQTLGGSGALKVGADFLK YFP
Sbjct 61 HGASLYLPMEGLNCYRHAIAPLLFGADHPVLKQQRVATIQTLGGSGALKVGADFLKRYFP 120
Query 121 DSEVWVSQPTWDNHIAIFNGAGFKTHFYPYFDAETRGLDFEGMLATLKQLPKHSIVLLHP 180
+S VWVS PTW+NH+AIF GAGF+ YP++D T G+ F +LATLK LP SIVLLHP
Sbjct 121 ESGVWVSDPTWENHVAIFAGAGFEVSTYPWYDEATNGVRFNDLLATLKTLPARSIVLLHP 180
Query 181 CCHNPTGVDLVPAQWDQVIDVLKAGHLIPFLDIAYQGFGDGMEQDAYAIRALDQSGLNFI 240
CCHNPTG DL QWD VI++LKA LIPFLDIAYQGFG GME+DAYAIRA+ +GL +
Sbjct 181 CCHNPTGADLTNDQWDAVIEILKARELIPFLDIAYQGFGAGMEEDAYAIRAIASAGLPAL 240
Query 241 VSNSFSKIFSLYGERVGGLTFVCDDAEAAQCTFGQLKATVRRIYSSPPTTGAWLVDQVLN 300
VSNSFSKIFSLYGERVGGL+ +C+DAEAA GQLKATVRR YSSPP GA +V VLN
Sbjct 241 VSNSFSKIFSLYGERVGGLSVMCEDAEAAGRVLGQLKATVRRNYSSPPNFGAQVVAAVLN 300
Query 301 DAELSQQWQNEVKEMRERILKMRIILRDELTKALPDRDFNYLVDQKGMFSYTGLTADQVD 360
D L W EV+EMR RIL MR L L+ +P+R+F+YL++Q+GMFSYTGL+A QVD
Sbjct 301 DEALKASWLAEVEEMRTRILAMRQELVKVLSTEMPERNFDYLLNQRGMFSYTGLSAAQVD 360
Query 361 TLREDYAIYLVRSGRICVAGLNMNNVYIVAKAMAEVL 397
LRE++ +YL+ SGR+CVAGLN NV VAKA A V+
Sbjct 361 RLREEFGVYLIASGRMCVAGLNTANVQRVAKAFAAVM 397
>P74861 Aromatic-amino-acid aminotransferase [Salmonella typhimurium
(strain LT2 / SGSC1412 / ATCC 700720)]
Length=397
Score = 506 bits (1304), Expect = 0.0
Identities = 251/397 (63%), Positives = 297/397 (75%), Gaps = 0/397 (0%)
Query 1 MFQHIPPYAGDPILSLMEQFNADSREAKVNLSIGLYYNEDSIVPQLDSVIEAQKRIEPRQ 60
MFQ + YAGDPILSLME+F DSR KVNLSIGLYYNED I+PQL +V EA+ R+ +
Sbjct 1 MFQKVDAYAGDPILSLMERFKDDSRHDKVNLSIGLYYNEDGIIPQLKTVAEAEARLNAQP 60
Query 61 NKVKPYLPMEGFKPYRDAIQTLLFGHNSPAVKAGRAVTIQTLGGSGALKVGADFLKNYFP 120
+ YLPMEG YR I LLFG + P ++ R TIQTLGGSGALKVGADFLK YFP
Sbjct 61 HGASLYLPMEGLNTYRHTIAPLLFGADHPVLQQQRVATIQTLGGSGALKVGADFLKRYFP 120
Query 121 DSEVWVSQPTWDNHIAIFNGAGFKTHFYPYFDAETRGLDFEGMLATLKQLPKHSIVLLHP 180
D+ VWVS PTW+NHIAIF GAGF+ YP++D T G+ F +LATL LP SIVLLHP
Sbjct 121 DAGVWVSDPTWENHIAIFAGAGFEVSTYPWYDDATNGIRFNDLLATLNTLPARSIVLLHP 180
Query 181 CCHNPTGVDLVPAQWDQVIDVLKAGHLIPFLDIAYQGFGDGMEQDAYAIRALDQSGLNFI 240
CCHNPTG DL P+QWD VI+++KA LIPFLDIAYQGFG GM+ DAY IRA+ +GL +
Sbjct 181 CCHNPTGADLTPSQWDAVIEIVKARDLIPFLDIAYQGFGAGMDDDAYVIRAIASAGLPAL 240
Query 241 VSNSFSKIFSLYGERVGGLTFVCDDAEAAQCTFGQLKATVRRIYSSPPTTGAWLVDQVLN 300
VSNSFSKIFSLYGERVGGL+ VC+DAE A GQLKATVRRIYSSPP GA +V VL
Sbjct 241 VSNSFSKIFSLYGERVGGLSVVCEDAEIAARVLGQLKATVRRIYSSPPCFGAQVVATVLG 300
Query 301 DAELSQQWQNEVKEMRERILKMRIILRDELTKALPDRDFNYLVDQKGMFSYTGLTADQVD 360
D L W EV MR RI+ MR L EL +PDR+F+YL+ Q+GMFSYTGL+ +QVD
Sbjct 301 DEALKAGWLAEVDAMRNRIISMRQTLVKELKAEMPDRNFDYLLQQRGMFSYTGLSEEQVD 360
Query 361 TLREDYAIYLVRSGRICVAGLNMNNVYIVAKAMAEVL 397
LR+++ +YL+ SGR+CVAGLN +NV+ VAKA A V+
Sbjct 361 RLRDEFGVYLIASGRMCVAGLNASNVHRVAKAFAAVM 397
>O85746 Tyrosine aminotransferase [Klebsiella pneumoniae]
Length=397
Score = 497 bits (1280), Expect = 7e-180
Identities = 248/397 (62%), Positives = 292/397 (74%), Gaps = 0/397 (0%)
Query 1 MFQHIPPYAGDPILSLMEQFNADSREAKVNLSIGLYYNEDSIVPQLDSVIEAQKRIEPRQ 60
MFQ + YAGDPILSLME+F D R KVNLSIGLYYN+D I+PQL +V EA+ R+
Sbjct 1 MFQKVDAYAGDPILSLMERFKEDPRSDKVNLSIGLYYNDDGIIPQLQAVAEAEARLNAEP 60
Query 61 NKVKPYLPMEGFKPYRDAIQTLLFGHNSPAVKAGRAVTIQTLGGSGALKVGADFLKNYFP 120
+ YLPMEGF YR AI LLFG A+K R +IQT+GGSGALKVGADFLK YFP
Sbjct 61 HGASLYLPMEGFSGYRQAIAPLLFGAEHTALKQNRIASIQTVGGSGALKVGADFLKRYFP 120
Query 121 DSEVWVSQPTWDNHIAIFNGAGFKTHFYPYFDAETRGLDFEGMLATLKQLPKHSIVLLHP 180
+S VWVS PTW+NHIAIF GAGF+ YP+FD T G+ FE +LA L+ LP IVLLHP
Sbjct 121 ESHVWVSDPTWENHIAIFEGAGFEVSTYPWFDKATNGVRFENLLAMLQTLPARDIVLLHP 180
Query 181 CCHNPTGVDLVPAQWDQVIDVLKAGHLIPFLDIAYQGFGDGMEQDAYAIRALDQSGLNFI 240
CCHNPTG DL PAQWD+V++VLKA LIPFLDIAYQGFG G+E+DAYAIRA+ +G+ +
Sbjct 181 CCHNPTGADLTPAQWDRVVEVLKARQLIPFLDIAYQGFGGGLEEDAYAIRAIASAGMPML 240
Query 241 VSNSFSKIFSLYGERVGGLTFVCDDAEAAQCTFGQLKATVRRIYSSPPTTGAWLVDQVLN 300
VSNSFSKIFSLYGERVGGL+ VC+D+E A GQLKATVRR YSSPP+ GA +V VLN
Sbjct 241 VSNSFSKIFSLYGERVGGLSVVCEDSETAGRVLGQLKATVRRNYSSPPSFGAQVVATVLN 300
Query 301 DAELSQQWQNEVKEMRERILKMRIILRDELTKALPDRDFNYLVDQKGMFSYTGLTADQVD 360
DA L WQ EV MR IL MR L D L + P +YL+ Q+GMFSYTG +A QVD
Sbjct 301 DAALKATWQAEVDAMRAHILTMRQALVDALQQVAPGSKVDYLLKQRGMFSYTGFSAAQVD 360
Query 361 TLREDYAIYLVRSGRICVAGLNMNNVYIVAKAMAEVL 397
LR+++ +YL+ SGR+ VAGLN NV VAKA V+
Sbjct 361 RLRDEFGVYLIASGRMRVAGLNSRNVQQVAKAFVAVM 397
>P72173 Aspartate aminotransferase [Pseudomonas aeruginosa (strain
ATCC 15692 / DSM 22644 / CIP 104116 / JCM 14847 / LMG 12228
/ 1C / PRS 101 / PAO1)]
Length=398
Score = 398 bits (1022), Expect = 1e-140
Identities = 202/398 (51%), Positives = 270/398 (68%), Gaps = 3/398 (1%)
Query 1 MFQHIPPYAGDPILSLMEQFNADSREAKVNLSIGLYYNEDSIVPQLDSVIEAQK-RIEPR 59
+F + DPIL L E FNAD+R K+NL +G+YYNE+ +P L +V A+K RIE
Sbjct 3 LFSAVEMAPRDPILGLNEAFNADTRPGKINLGVGVYYNEEGRIPLLRAVQAAEKARIEA- 61
Query 60 QNKVKPYLPMEGFKPYRDAIQTLLFGHNSPAVKAGRAVTIQTLGGSGALKVGADFLKNYF 119
+ + YLP+EG Y +Q LLFG+ S + AGR VT Q +GG+GALK+GADFLK
Sbjct 62 -HAPRGYLPIEGIAAYDQGVQKLLFGNESELLAAGRVVTTQAVGGTGALKLGADFLKRLL 120
Query 120 PDSEVWVSQPTWDNHIAIFNGAGFKTHFYPYFDAETRGLDFEGMLATLKQLPKHSIVLLH 179
PD+ V +S P+W+NH A+F AGF Y Y+DA + G++ G+L L LP SIV+LH
Sbjct 121 PDATVAISDPSWENHRALFEAAGFPVQNYRYYDAASNGVNRAGLLEDLNALPARSIVVLH 180
Query 180 PCCHNPTGVDLVPAQWDQVIDVLKAGHLIPFLDIAYQGFGDGMEQDAYAIRALDQSGLNF 239
CCHNPTGVDL W QV+DVLKA +PFLDIAYQGFG+G+E+DA A+R QSGL+F
Sbjct 181 ACCHNPTGVDLELDDWKQVLDVLKAKGHVPFLDIAYQGFGNGIEEDAAAVRLFAQSGLSF 240
Query 240 IVSNSFSKIFSLYGERVGGLTFVCDDAEAAQCTFGQLKATVRRIYSSPPTTGAWLVDQVL 299
VS+SFSK FSLYGERVG L+ V + + + Q+K +R YS+PPT GA +V VL
Sbjct 241 FVSSSFSKSFSLYGERVGALSIVTESRDESARVLSQVKRVIRTNYSNPPTHGASVVSSVL 300
Query 300 NDAELSQQWQNEVKEMRERILKMRIILRDELTKALPDRDFNYLVDQKGMFSYTGLTADQV 359
N EL W+ E+ EMR+RI MR+ + ++L RDF+++ Q+GMFSY+GLTADQV
Sbjct 301 NSPELRALWEQELGEMRDRIRDMRLAMVEQLAAHGAKRDFSFVGRQRGMFSYSGLTADQV 360
Query 360 DTLREDYAIYLVRSGRICVAGLNMNNVYIVAKAMAEVL 397
+ L+ ++ IY V +GRICVA LN +N+ + KA+ +VL
Sbjct 361 ERLKTEFGIYAVSTGRICVAALNKSNLETITKAIVQVL 398
>P44425 Aspartate aminotransferase [Haemophilus influenzae (strain
ATCC 51907 / DSM 11121 / KW20 / Rd)]
Length=396
Score = 360 bits (925), Expect = 4e-126
Identities = 174/397 (44%), Positives = 259/397 (65%), Gaps = 1/397 (0%)
Query 1 MFQHIPPYAGDPILSLMEQFNADSREAKVNLSIGLYYNEDSIVPQLDSVIEAQKRIEPRQ 60
MF+HI DPIL L E F +++RE K+NL IG+Y + P + +V EA+KR+ ++
Sbjct 1 MFEHIKAAPADPILGLGEAFKSETRENKINLGIGVYKDAQGTTPIMHAVKEAEKRLFDKE 60
Query 61 NKVKPYLPMEGFKPYRDAIQTLLFGHNSPAVKAGRAVTIQTLGGSGALKVGADFLKNYFP 120
K K YL ++G Y + + LLFG +S +++ RA T+Q+LGG+GAL++ A+F+K
Sbjct 61 -KTKNYLTIDGIADYNEQTKALLFGKDSEVIQSNRARTVQSLGGTGALRIAAEFIKRQTK 119
Query 121 DSEVWVSQPTWDNHIAIFNGAGFKTHFYPYFDAETRGLDFEGMLATLKQLPKHSIVLLHP 180
VW+S PTW NH AIFN G Y Y+DAE + LD+E +L L Q + +VLLH
Sbjct 120 AQNVWISTPTWPNHNAIFNAVGMTIREYRYYDAERKALDWEHLLEDLSQASEGDVVLLHG 179
Query 181 CCHNPTGVDLVPAQWDQVIDVLKAGHLIPFLDIAYQGFGDGMEQDAYAIRALDQSGLNFI 240
CCHNPTG+D P QW ++ + +P D AYQG +G+++DAY +RA + +
Sbjct 180 CCHNPTGIDPTPEQWQELAALSAKNGWLPLFDFAYQGLANGLDEDAYGLRAFAANHKELL 239
Query 241 VSNSFSKIFSLYGERVGGLTFVCDDAEAAQCTFGQLKATVRRIYSSPPTTGAWLVDQVLN 300
V++SFSK F LY ERVG T V ++AE A + Q+K+ +R +YS+P + G V VLN
Sbjct 240 VASSFSKNFGLYNERVGAFTLVAENAEIASTSLTQVKSIIRTLYSNPASHGGATVATVLN 299
Query 301 DAELSQQWQNEVKEMRERILKMRIILRDELTKALPDRDFNYLVDQKGMFSYTGLTADQVD 360
DA+L Q+W+NE+ EMRERI KMR + L + ++DF+++++Q GMFS++GLT +QVD
Sbjct 300 DAQLRQEWENELTEMRERIKKMRHLFVQLLKEYGAEQDFSFIIEQNGMFSFSGLTGEQVD 359
Query 361 TLREDYAIYLVRSGRICVAGLNMNNVYIVAKAMAEVL 397
L+ ++AIY VRSGRI VAG+ +N+ + +++ +VL
Sbjct 360 RLKNEFAIYAVRSGRINVAGITEDNIRYLCESIVKVL 396
>Q56114 Aspartate aminotransferase [Salmonella typhi]
Length=396
Score = 323 bits (827), Expect = 3e-111
Identities = 166/397 (42%), Positives = 237/397 (60%), Gaps = 1/397 (0%)
Query 1 MFQHIPPYAGDPILSLMEQFNADSREAKVNLSIGLYYNEDSIVPQLDSVIEAQKRIEPRQ 60
MF++I DPIL L + F AD R K+NL IG+Y +E P L SV +A++ + +
Sbjct 1 MFENITAAPADPILGLADLFRADDRPGKINLGIGVYKDETGKTPVLTSVKKAEQYLLENE 60
Query 61 NKVKPYLPMEGFKPYRDAIQTLLFGHNSPAVKAGRAVTIQTLGGSGALKVGADFLKNYFP 120
K YL ++G + Q LLFG S + RA T QT GG+GAL++ ADFL P
Sbjct 61 T-TKNYLGIDGIPEFARCTQELLFGKGSALINDKRARTAQTPGGTGALRIAADFLAKNTP 119
Query 121 DSEVWVSQPTWDNHIAIFNGAGFKTHFYPYFDAETRGLDFEGMLATLKQLPKHSIVLLHP 180
VWVS P+W NH ++FN AG + Y Y+DAE LDFE + A+L + +VL H
Sbjct 120 VKRVWVSNPSWPNHKSVFNAAGLEVREYAYYDAENHSLDFEALQASLSEAQAGDVVLFHG 179
Query 181 CCHNPTGVDLVPAQWDQVIDVLKAGHLIPFLDIAYQGFGDGMEQDAYAIRALDQSGLNFI 240
CCHNPTG+D QW + ++ +P D AYQGF G+E+DA +RA I
Sbjct 180 CCHNPTGIDPTLEQWQVLAELSVEKGWLPLFDFAYQGFARGLEEDAEGLRAFAALHKELI 239
Query 241 VSNSFSKIFSLYGERVGGLTFVCDDAEAAQCTFGQLKATVRRIYSSPPTTGAWLVDQVLN 300
V++S+SK F LY ERVG T V DAE F Q+K+ +R YS+PP GA +V +L+
Sbjct 240 VASSYSKNFGLYNERVGACTLVAADAETVDRAFSQMKSAIRANYSNPPAHGASIVATILS 299
Query 301 DAELSQQWQNEVKEMRERILKMRIILRDELTKALPDRDFNYLVDQKGMFSYTGLTADQVD 360
+ L W+ E+ +MR+RI +MR + + L + +RDF++++ Q GMFS++GLT DQV
Sbjct 300 NDALRAIWEQELTDMRQRIQRMRQLFVNTLQEKGANRDFSFIIKQNGMFSFSGLTKDQVL 359
Query 361 TLREDYAIYLVRSGRICVAGLNMNNVYIVAKAMAEVL 397
LRE++ +Y V SGR+ VAG+ +N+ + +A+ VL
Sbjct 360 RLREEFGVYAVASGRVNVAGMTPDNMAPLCEAIVAVL 396
>P58661 Aspartate aminotransferase [Salmonella typhimurium (strain
LT2 / SGSC1412 / ATCC 700720)]
Length=396
Score = 322 bits (825), Expect = 5e-111
Identities = 166/397 (42%), Positives = 237/397 (60%), Gaps = 1/397 (0%)
Query 1 MFQHIPPYAGDPILSLMEQFNADSREAKVNLSIGLYYNEDSIVPQLDSVIEAQKRIEPRQ 60
MF++I DPIL L + F AD R K+NL IG+Y +E P L SV +A++ + +
Sbjct 1 MFENITAAPADPILGLADLFRADDRPGKINLGIGVYKDETGKTPVLTSVKKAEQYLLENE 60
Query 61 NKVKPYLPMEGFKPYRDAIQTLLFGHNSPAVKAGRAVTIQTLGGSGALKVGADFLKNYFP 120
K YL ++G + Q LLFG S + RA T QT GG+GAL++ ADFL P
Sbjct 61 T-TKNYLGIDGIPEFARCTQELLFGKGSALINDKRARTAQTPGGTGALRIAADFLAKNTP 119
Query 121 DSEVWVSQPTWDNHIAIFNGAGFKTHFYPYFDAETRGLDFEGMLATLKQLPKHSIVLLHP 180
VWVS P+W NH ++FN AG + Y Y+DAE LDFE + A+L + +VL H
Sbjct 120 VKRVWVSNPSWPNHKSVFNAAGLEVREYAYYDAENHTLDFEALQASLSEAQAGDVVLFHG 179
Query 181 CCHNPTGVDLVPAQWDQVIDVLKAGHLIPFLDIAYQGFGDGMEQDAYAIRALDQSGLNFI 240
CCHNPTG+D QW + ++ +P D AYQGF G+E+DA +RA I
Sbjct 180 CCHNPTGIDPTLEQWQVLAELSVEKGWLPLFDFAYQGFARGLEEDAEGLRAFAALHKELI 239
Query 241 VSNSFSKIFSLYGERVGGLTFVCDDAEAAQCTFGQLKATVRRIYSSPPTTGAWLVDQVLN 300
V++S+SK F LY ERVG T V DAE F Q+K+ +R YS+PP GA +V +L+
Sbjct 240 VASSYSKNFGLYNERVGACTLVAADAETVDRAFSQMKSAIRANYSNPPAHGASIVATILS 299
Query 301 DAELSQQWQNEVKEMRERILKMRIILRDELTKALPDRDFNYLVDQKGMFSYTGLTADQVD 360
+ L W+ E+ +MR+RI +MR + + L + +RDF++++ Q GMFS++GLT DQV
Sbjct 300 NDALRAIWEQELTDMRQRIQRMRQLFVNTLQEKGANRDFSFIIKQNGMFSFSGLTKDQVL 359
Query 361 TLREDYAIYLVRSGRICVAGLNMNNVYIVAKAMAEVL 397
LRE++ +Y V SGR+ VAG+ +N+ + +A+ VL
Sbjct 360 RLREEFGVYAVASGRVNVAGMTPDNMAPLCEAIVAVL 396
>P00506 Aspartate aminotransferase, mitochondrial [Sus scrofa]
Length=430
Score = 317 bits (813), Expect = 1e-108
Identities = 164/396 (41%), Positives = 243/396 (61%), Gaps = 5/396 (1%)
Query 4 HIPPYAGDPILSLMEQFNADSREAKVNLSIGLYYNEDSIVPQLDSVIEAQKRIEPRQNKV 63
H+ DPIL + E F D+ K+NL +G Y +++ L SV +A+ +I + N
Sbjct 35 HVEMGPPDPILGVTEAFKRDTNSKKMNLGVGAYRDDNGKPYVLPSVRKAEAQIAAK-NLD 93
Query 64 KPYLPMEGFKPYRDAIQTLLFGHNSPAVKAGRAVTIQTLGGSGALKVGADFLKNYFPDS- 122
K YLP+ G + A L G N+ +K+GR VT+QT+ G+GAL++GA+FL+ +F S
Sbjct 94 KEYLPIGGLAEFCKASAELALGENNEVLKSGRYVTVQTISGTGALRIGANFLQRFFKFSR 153
Query 123 EVWVSQPTWDNHIAIFNGAGFKTHFYPYFDAETRGLDFEGMLATLKQLPKHSIVLLHPCC 182
+V++ +P+W NH IF AG + H Y Y+D +T G DF G L + ++P S++LLH C
Sbjct 154 DVFLPKPSWGNHTPIFRDAGMQLHSYRYYDPKTCGFDFTGALEDISKIPAQSVILLHACA 213
Query 183 HNPTGVDLVPAQWDQVIDVLKAGHLIPFLDIAYQGF--GDGMEQDAYAIRALDQSGLNFI 240
HNPTGVD P QW ++ ++K +L F D+AYQGF GDG +DA+A+R + G+N
Sbjct 214 HNPTGVDPRPEQWKEMATLVKKNNLFAFFDMAYQGFASGDG-NKDAWAVRHFIEQGINVC 272
Query 241 VSNSFSKIFSLYGERVGGLTFVCDDAEAAQCTFGQLKATVRRIYSSPPTTGAWLVDQVLN 300
+ S++K LYGERVG T VC DAE A+ QLK +R +YS+PP GA + +L
Sbjct 273 LCQSYAKNMGLYGERVGAFTVVCKDAEEAKRVESQLKILIRPMYSNPPVNGARIASTILT 332
Query 301 DAELSQQWQNEVKEMRERILKMRIILRDELTKALPDRDFNYLVDQKGMFSYTGLTADQVD 360
+L QQW EVK M +RI+ MR L L K ++ ++VDQ GMF +TG+ +QV+
Sbjct 333 SPDLRQQWLQEVKGMADRIISMRTQLVSNLKKEGSSHNWQHIVDQIGMFCFTGIKPEQVE 392
Query 361 TLREDYAIYLVRSGRICVAGLNMNNVYIVAKAMAEV 396
L ++++IY+ + GRI VAG+ NV +A A+ +V
Sbjct 393 RLTKEFSIYMTKDGRISVAGVTSGNVGYLAHAIHQV 428
>P12344 Aspartate aminotransferase, mitochondrial [Bos taurus]
Length=430
Score = 317 bits (812), Expect = 1e-108
Identities = 164/396 (41%), Positives = 242/396 (61%), Gaps = 5/396 (1%)
Query 4 HIPPYAGDPILSLMEQFNADSREAKVNLSIGLYYNEDSIVPQLDSVIEAQKRIEPRQNKV 63
H+ DPIL + E F D+ K+NL +G Y +++ L SV +A+ +I + N
Sbjct 35 HVEMGPPDPILGVTEAFKRDTNSKKMNLGVGAYRDDNGKPYVLPSVRKAEAQIAAK-NLD 93
Query 64 KPYLPMEGFKPYRDAIQTLLFGHNSPAVKAGRAVTIQTLGGSGALKVGADFLKNYFPDS- 122
K YLP+ G + A L G N+ +K+GR VT+QT+ G+GAL++GA FL+ +F S
Sbjct 94 KEYLPIAGLAEFCKASAELALGENNEVLKSGRYVTVQTISGTGALRIGASFLQRFFKFSR 153
Query 123 EVWVSQPTWDNHIAIFNGAGFKTHFYPYFDAETRGLDFEGMLATLKQLPKHSIVLLHPCC 182
+V++ +PTW NH IF AG + Y Y+D +T G DF G + + ++P S++LLH C
Sbjct 154 DVFLPKPTWGNHTPIFRDAGMQLQSYRYYDPKTCGFDFTGAIEDISKIPAQSVILLHACA 213
Query 183 HNPTGVDLVPAQWDQVIDVLKAGHLIPFLDIAYQGF--GDGMEQDAYAIRALDQSGLNFI 240
HNPTGVD P QW ++ V+K +L F D+AYQGF GDG +DA+A+R + G+N
Sbjct 214 HNPTGVDPRPEQWKEMATVVKKNNLFAFFDMAYQGFASGDG-NKDAWAVRHFIEQGINVC 272
Query 241 VSNSFSKIFSLYGERVGGLTFVCDDAEAAQCTFGQLKATVRRIYSSPPTTGAWLVDQVLN 300
+ S++K LYGERVG T VC DAE A+ QLK +R +YS+PP GA + +L
Sbjct 273 LCQSYAKNMGLYGERVGAFTVVCKDAEEAKRVESQLKILIRPMYSNPPINGARIASTILT 332
Query 301 DAELSQQWQNEVKEMRERILKMRIILRDELTKALPDRDFNYLVDQKGMFSYTGLTADQVD 360
+L +QW +EVK M +RI+ MR L L K ++ +++DQ GMF YTGL +QV+
Sbjct 333 SPDLRKQWLHEVKGMADRIISMRTQLVSNLKKEGSSHNWQHIIDQIGMFCYTGLKPEQVE 392
Query 361 TLREDYAIYLVRSGRICVAGLNMNNVYIVAKAMAEV 396
L ++++IY+ + GRI VAG+ NV +A A+ +V
Sbjct 393 RLTKEFSIYMTKDGRISVAGVTSGNVAYLAHAIHQV 428
>P00509 Aspartate aminotransferase [Escherichia coli (strain K12)]
Length=396
Score = 315 bits (807), Expect = 3e-108
Identities = 163/397 (41%), Positives = 235/397 (59%), Gaps = 1/397 (0%)
Query 1 MFQHIPPYAGDPILSLMEQFNADSREAKVNLSIGLYYNEDSIVPQLDSVIEAQKRIEPRQ 60
MF++I DPIL L + F AD R K+NL IG+Y +E P L SV +A++ + +
Sbjct 1 MFENITAAPADPILGLADLFRADERPGKINLGIGVYKDETGKTPVLTSVKKAEQYLLENE 60
Query 61 NKVKPYLPMEGFKPYRDAIQTLLFGHNSPAVKAGRAVTIQTLGGSGALKVGADFLKNYFP 120
K YL ++G + Q LLFG S + RA T QT GG+GAL+V ADFL
Sbjct 61 T-TKNYLGIDGIPEFGRCTQELLFGKGSALINDKRARTAQTPGGTGALRVAADFLAKNTS 119
Query 121 DSEVWVSQPTWDNHIAIFNGAGFKTHFYPYFDAETRGLDFEGMLATLKQLPKHSIVLLHP 180
VWVS P+W NH ++FN AG + Y Y+DAE LDF+ ++ +L + +VL H
Sbjct 120 VKRVWVSNPSWPNHKSVFNSAGLEVREYAYYDAENHTLDFDALINSLNEAQAGDVVLFHG 179
Query 181 CCHNPTGVDLVPAQWDQVIDVLKAGHLIPFLDIAYQGFGDGMEQDAYAIRALDQSGLNFI 240
CCHNPTG+D QW + + +P D AYQGF G+E+DA +RA I
Sbjct 180 CCHNPTGIDPTLEQWQTLAQLSVEKGWLPLFDFAYQGFARGLEEDAEGLRAFAAMHKELI 239
Query 241 VSNSFSKIFSLYGERVGGLTFVCDDAEAAQCTFGQLKATVRRIYSSPPTTGAWLVDQVLN 300
V++S+SK F LY ERVG T V D+E F Q+KA +R YS+PP GA +V +L+
Sbjct 240 VASSYSKNFGLYNERVGACTLVAADSETVDRAFSQMKAAIRANYSNPPAHGASVVATILS 299
Query 301 DAELSQQWQNEVKEMRERILKMRIILRDELTKALPDRDFNYLVDQKGMFSYTGLTADQVD 360
+ L W+ E+ +MR+RI +MR + + L + +RDF++++ Q GMFS++GLT +QV
Sbjct 300 NDALRAIWEQELTDMRQRIQRMRQLFVNTLQEKGANRDFSFIIKQNGMFSFSGLTKEQVL 359
Query 361 TLREDYAIYLVRSGRICVAGLNMNNVYIVAKAMAEVL 397
LRE++ +Y V SGR+ VAG+ +N+ + +A+ VL
Sbjct 360 RLREEFGVYAVASGRVNVAGMTPDNMAPLCEAIVAVL 396
>P08907 Aspartate aminotransferase, mitochondrial [Equus caballus]
Length=401
Score = 313 bits (802), Expect = 2e-107
Identities = 162/396 (41%), Positives = 242/396 (61%), Gaps = 5/396 (1%)
Query 4 HIPPYAGDPILSLMEQFNADSREAKVNLSIGLYYNEDSIVPQLDSVIEAQKRIEPRQNKV 63
H+ DPIL + E + D+ K+NL +G Y +++ L SV +A+ +I + N
Sbjct 6 HVEMGPPDPILGVTEAYKRDTNSKKMNLGVGAYRDDNGKPYVLPSVRKAEAQIAAK-NLD 64
Query 64 KPYLPMEGFKPYRDAIQTLLFGHNSPAVKAGRAVTIQTLGGSGALKVGADFLKNYFPDS- 122
K YLP+ G + A L G NS A+K+GR VT+Q++ G+GAL++GA+FL+ +F S
Sbjct 65 KEYLPIGGLAEFCKASAELALGENSEALKSGRYVTVQSISGTGALRIGANFLQRFFKFSR 124
Query 123 EVWVSQPTWDNHIAIFNGAGFKTHFYPYFDAETRGLDFEGMLATLKQLPKHSIVLLHPCC 182
+V++ +P+W NH IF AG + H Y Y+D +T G D G L + ++P+ SI+LLH C
Sbjct 125 DVFLPKPSWGNHTPIFRDAGLQLHAYRYYDPKTCGFDVTGALEDISKIPQQSIILLHACA 184
Query 183 HNPTGVDLVPAQWDQVIDVLKAGHLIPFLDIAYQGF--GDGMEQDAYAIRALDQSGLNFI 240
HNPTGVD P QW ++ ++K +L F D+AYQGF GDG +DA+A+R + G+N
Sbjct 185 HNPTGVDPRPEQWKEIATLVKKNNLFAFFDMAYQGFASGDG-NKDAWAVRYFIEQGINVC 243
Query 241 VSNSFSKIFSLYGERVGGLTFVCDDAEAAQCTFGQLKATVRRIYSSPPTTGAWLVDQVLN 300
+ S++K LYGERVG T VC DA+ A+ QLK +R +YS+PP GA + +L
Sbjct 244 LCQSYAKNMGLYGERVGAFTMVCKDADEAKRVESQLKILIRPLYSNPPLNGARIASTILT 303
Query 301 DAELSQQWQNEVKEMRERILKMRIILRDELTKALPDRDFNYLVDQKGMFSYTGLTADQVD 360
+L +QW EVK M +RI+ MR L L K + ++ DQ GMF +TGL +QV+
Sbjct 304 SPDLRKQWLQEVKGMADRIISMRTQLVSNLKKEGSSHSWQHIADQIGMFCFTGLKPEQVE 363
Query 361 TLREDYAIYLVRSGRICVAGLNMNNVYIVAKAMAEV 396
L ++++IY+ + GRI VAG+ NV +A A+ +V
Sbjct 364 RLTKEFSIYMTKDGRISVAGVTSGNVGYLAHAIHQV 399
>P05202 Aspartate aminotransferase, mitochondrial [Mus musculus]
Length=430
Score = 313 bits (802), Expect = 5e-107
Identities = 163/396 (41%), Positives = 242/396 (61%), Gaps = 5/396 (1%)
Query 4 HIPPYAGDPILSLMEQFNADSREAKVNLSIGLYYNEDSIVPQLDSVIEAQKRIEPRQNKV 63
H+ DPIL + E F D+ K+NL +G Y +++ L SV +A+ +I + N
Sbjct 35 HVEMGPPDPILGVTEAFKRDTNSKKMNLGVGAYRDDNGKPYVLPSVRKAEAQIAAK-NLD 93
Query 64 KPYLPMEGFKPYRDAIQTLLFGHNSPAVKAGRAVTIQTLGGSGALKVGADFLKNYFPDS- 122
K YLP+ G + A L G N+ +K+GR VT+QT+ G+GAL+VGA FL+ +F S
Sbjct 94 KEYLPIGGLAEFCKASAELALGENNEVLKSGRFVTVQTISGTGALRVGASFLQRFFKFSR 153
Query 123 EVWVSQPTWDNHIAIFNGAGFKTHFYPYFDAETRGLDFEGMLATLKQLPKHSIVLLHPCC 182
+V++ +P+W NH IF AG + Y Y+D +T G DF G L + ++P+ S++LLH C
Sbjct 154 DVFLPKPSWGNHTPIFRDAGMQLQGYRYYDPKTCGFDFSGALEDISKIPEQSVLLLHACA 213
Query 183 HNPTGVDLVPAQWDQVIDVLKAGHLIPFLDIAYQGF--GDGMEQDAYAIRALDQSGLNFI 240
HNPTGVD P QW ++ V+K +L F D+AYQGF GDG ++DA+A+R + G+N
Sbjct 214 HNPTGVDPRPEQWKEIASVVKKKNLFAFFDMAYQGFASGDG-DKDAWAVRHFIEQGINVC 272
Query 241 VSNSFSKIFSLYGERVGGLTFVCDDAEAAQCTFGQLKATVRRIYSSPPTTGAWLVDQVLN 300
+ S++K LYGERVG T VC DAE A+ QLK +R +YS+PP GA + +L
Sbjct 273 LCQSYAKNMGLYGERVGAFTVVCKDAEEAKRVESQLKILIRPLYSNPPLNGARIAATILT 332
Query 301 DAELSQQWQNEVKEMRERILKMRIILRDELTKALPDRDFNYLVDQKGMFSYTGLTADQVD 360
+L +QW EVK M +RI+ MR L L K ++ ++ DQ GMF +TGL +QV+
Sbjct 333 SPDLRKQWLQEVKGMADRIISMRTQLVSNLKKEGSSHNWQHITDQIGMFCFTGLKPEQVE 392
Query 361 TLREDYAIYLVRSGRICVAGLNMNNVYIVAKAMAEV 396
L +++++Y+ + GRI VAG+ NV +A A+ +V
Sbjct 393 RLTKEFSVYMTKDGRISVAGVTSGNVGYLAHAIHQV 428
>P00505 Aspartate aminotransferase, mitochondrial [Homo sapiens]
Length=430
Score = 313 bits (802), Expect = 5e-107
Identities = 164/396 (41%), Positives = 244/396 (62%), Gaps = 5/396 (1%)
Query 4 HIPPYAGDPILSLMEQFNADSREAKVNLSIGLYYNEDSIVPQLDSVIEAQKRIEPRQNKV 63
H+ DPIL + E F D+ K+NL +G Y +++ L SV +A+ +I + N
Sbjct 35 HVEMGPPDPILGVTEAFKRDTNSKKMNLGVGAYRDDNGKPYVLPSVRKAEAQIAAK-NLD 93
Query 64 KPYLPMEGFKPYRDAIQTLLFGHNSPAVKAGRAVTIQTLGGSGALKVGADFLKNYFPDS- 122
K YLP+ G + A L G NS +K+GR VT+QT+ G+GAL++GA FL+ +F S
Sbjct 94 KEYLPIGGLAEFCKASAELALGENSEVLKSGRFVTVQTISGTGALRIGASFLQRFFKFSR 153
Query 123 EVWVSQPTWDNHIAIFNGAGFKTHFYPYFDAETRGLDFEGMLATLKQLPKHSIVLLHPCC 182
+V++ +PTW NH IF AG + Y Y+D +T G DF G + + ++P+ S++LLH C
Sbjct 154 DVFLPKPTWGNHTPIFRDAGMQLQGYRYYDPKTCGFDFTGAVEDISKIPEQSVLLLHACA 213
Query 183 HNPTGVDLVPAQWDQVIDVLKAGHLIPFLDIAYQGF--GDGMEQDAYAIRALDQSGLNFI 240
HNPTGVD P QW ++ V+K +L F D+AYQGF GDG ++DA+A+R + G+N
Sbjct 214 HNPTGVDPRPEQWKEIATVVKKRNLFAFFDMAYQGFASGDG-DKDAWAVRHFIEQGINVC 272
Query 241 VSNSFSKIFSLYGERVGGLTFVCDDAEAAQCTFGQLKATVRRIYSSPPTTGAWLVDQVLN 300
+ S++K LYGERVG T VC DA+ A+ QLK +R +YS+PP GA + +LN
Sbjct 273 LCQSYAKNMGLYGERVGAFTMVCKDADEAKRVESQLKILIRPMYSNPPLNGARIAAAILN 332
Query 301 DAELSQQWQNEVKEMRERILKMRIILRDELTKALPDRDFNYLVDQKGMFSYTGLTADQVD 360
+L +QW EVK M +RI+ MR L L K ++ ++ DQ GMF +TGL +QV+
Sbjct 333 TPDLRKQWLQEVKVMADRIIGMRTQLVSNLKKEGSTHNWQHITDQIGMFCFTGLKPEQVE 392
Query 361 TLREDYAIYLVRSGRICVAGLNMNNVYIVAKAMAEV 396
L ++++IY+ + GRI VAG+ +NV +A A+ +V
Sbjct 393 RLIKEFSIYMTKDGRISVAGVTSSNVGYLAHAIHQV 428
Lambda K H a alpha
0.322 0.139 0.420 0.792 4.96
Gapped
Lambda K H a alpha sigma
0.267 0.0410 0.140 1.90 42.6 43.6
Effective search space used: 1657892
Database: a102b2436838460a35fb70a1b315d9d8.SwissProt.fasta
Posted date: May 14, 2024 5:52 AM
Number of letters in database: 5,294
Number of sequences in database: 13
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Neighboring words threshold: 11
Window for multiple hits: 40
Loading
Data ...
