Comparative Genomics

ACIAD0300 / SwissProt Alignments

BLASTP 2.12.0+


Reference: Stephen F. Altschul, Thomas L. Madden, Alejandro A.
Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J.
Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of
protein database search programs", Nucleic Acids Res. 25:3389-3402.


Reference for composition-based statistics: Alejandro A. Schaffer,
L. Aravind, Thomas L. Madden, Sergei Shavirin, John L. Spouge, Yuri
I. Wolf, Eugene V. Koonin, and Stephen F. Altschul (2001),
"Improving the accuracy of PSI-BLAST protein database searches with
composition-based statistics and other refinements", Nucleic Acids
Res. 29:2994-3005.



Database: 1129b51cd6f38b376077f9b2010c6bc7.SwissProt.fasta
           18 sequences; 1,845 total letters



Query= ACIAD0300

Length=147
                                                                      Score     E
Sequences producing significant alignments:                          (Bits)  Value

Q9HWC3 Protein translocase subunit SecE [Pseudomonas aeruginosa (...  87.8    5e-27
Q9ZNE7 Protein translocase subunit SecE [Vibrio alginolyticus]        75.5    3e-22
Q9KV36 Protein translocase subunit SecE [Vibrio cholerae serotype...  72.8    4e-21
P0AG97 Protein translocase subunit SecE [Escherichia coli O6:H1 (...  68.6    2e-19
P0AG98 Protein translocase subunit SecE [Escherichia coli O157:H7]    68.6    2e-19
P0AG96 Protein translocase subunit SecE [Escherichia coli (strain...  68.6    2e-19
P0A2D3 Protein translocase subunit SecE [Salmonella typhimurium (...  66.2    1e-18
P0A2D4 Protein translocase subunit SecE [Salmonella typhi]            66.2    1e-18
Q8KA64 Protein translocase subunit SecE [Buchnera aphidicola subs...  53.1    1e-13
P43805 Protein translocase subunit SecE [Haemophilus influenzae (...  45.8    5e-11
P38382 Protein translocase subunit SecE [Synechocystis sp. (strai...  43.1    3e-10
P38383 Protein translocase subunit SecE [Thermus thermophilus (st...  42.4    4e-10
O51356 Protein translocase subunit SecE [Borreliella burgdorferi ...  40.0    3e-09
P38381 Protein translocase subunit SecE [Bacillus licheniformis]      39.3    6e-09
P36691 Protein translocase subunit SecE [Streptomyces virginiae]      36.6    1e-07
D0VWU4 Protein translocase subunit SecE [Aquifex aeolicus (strain...  35.8    1e-07
P0A4G8 Protein translocase subunit SecE [Streptomyces coelicolor ...  35.8    2e-07
P36690 Protein translocase subunit SecE [Streptomyces griseus]        35.0    4e-07


>Q9HWC3 Protein translocase subunit SecE [Pseudomonas aeruginosa 
(strain ATCC 15692 / DSM 22644 / CIP 104116 / JCM 14847 / 
LMG 12228 / 1C / PRS 101 / PAO1)]
Length=122

 Score = 87.8 bits (216),  Expect = 5e-27
 Identities = 46/126 (37%), Positives = 74/126 (59%), Gaps = 5/126 (4%)

Query  21   SAEVVTSGSPLDVVLWVIALALLIGAAMVNQYLPAYWPPANNIWVRVGVILACIVVALGL  80
            +A+     S  D++ W++   L++ A + NQY  A       I  RV  IL   V+A  L
Sbjct  2    NAKAEAKESRFDLLKWLLVAVLVVVAVVGNQYFSA-----QPILYRVLGILVLAVIAAFL  56

Query  81   LYATHQGKGFIRLLKDARIELRRVTWPTKQETVTTSWQVLLVVVITSIVLWCFDYGLGWL  140
               T +G+ F  L K+AR+E+R+V WP++QET  T+  V+ VV++ +++LW  D  LGWL
Sbjct  57   ALQTAKGQAFFSLAKEARVEIRKVVWPSRQETTQTTLIVVAVVLVMALLLWGLDSLLGWL  116

Query  141  IKLIIG  146
            + +I+G
Sbjct  117  VSMIVG  122


>Q9ZNE7 Protein translocase subunit SecE [Vibrio alginolyticus]
Length=126

 Score = 75.5 bits (184),  Expect = 3e-22
 Identities = 44/125 (35%), Positives = 71/125 (57%), Gaps = 8/125 (6%)

Query  20   NSAEVVTSGSPLDVVLWVIALALLIGAAMVNQYLPAYWPPANNIWVRVGVILACIVVALG  79
            N+AE   S +  D   W+ A  +L  AA+V  YL        ++ VR   ++  I  ALG
Sbjct  4    NNAETPDSSNAADTFKWLAAF-VLAAAAVVGNYLYGEM----SVVVRAAGVVVLIAAALG  58

Query  80   LLYATHQGKGFIRLLKDARIELRRVTWPTKQETVTTSWQVLLVVVITSIVLWCFDYGLGW  139
            +   T +GK  I   K++R+E+R+V WPT+QET+ T+  VL V ++ ++VLW  D   G 
Sbjct  59   VAATTTKGKAAISFAKESRMEVRKVVWPTRQETMQTTLIVLAVSIVMALVLWGID---GI  115

Query  140  LIKLI  144
            +++L+
Sbjct  116  MVRLV  120


>Q9KV36 Protein translocase subunit SecE [Vibrio cholerae serotype 
O1 (strain ATCC 39315 / El Tor Inaba N16961)]
Length=126

 Score = 72.8 bits (177),  Expect = 4e-21
 Identities = 42/125 (34%), Positives = 70/125 (56%), Gaps = 8/125 (6%)

Query  20   NSAEVVTSGSPLDVVLWVIALALLIGAAMVNQYLPAYWPPANNIWVRVGVILACIVVALG  79
            N+AE   S +  D + WV    LL+ AA+V  YL        ++  R   ++  I  ALG
Sbjct  4    NNAEAPDSSNAADTLKWVATFVLLV-AAVVGNYLYGEL----SVVARAAGVIVLIAAALG  58

Query  80   LLYATHQGKGFIRLLKDARIELRRVTWPTKQETVTTSWQVLLVVVITSIVLWCFDYGLGW  139
            +   T +GK  I   +++R+E+R+V WPT+QET+ T+  VL V ++ ++ LW  D   G 
Sbjct  59   VAATTTKGKEAIVFARESRMEVRKVVWPTRQETMQTTLIVLAVSIVMALALWGID---GI  115

Query  140  LIKLI  144
            +++L+
Sbjct  116  MVRLV  120


>P0AG97 Protein translocase subunit SecE [Escherichia coli O6:H1 
(strain CFT073 / ATCC 700928 / UPEC)]
Length=127

 Score = 68.6 bits (166),  Expect = 2e-19
 Identities = 41/126 (33%), Positives = 65/126 (52%), Gaps = 5/126 (4%)

Query  21   SAEVVTSGSPLDVVLWVIALALLIGAAMVNQYLPAYWPPANNIWVRVGVILACIVVALGL  80
            + E   SG  L+ + WV+ +ALL+ A + N        P     +R   ++  I  A G+
Sbjct  4    NTEAQGSGRGLEAMKWVVVVALLLVAIVGNYLYRDIMLP-----LRALAVVILIAAAGGV  58

Query  81   LYATHQGKGFIRLLKDARIELRRVTWPTKQETVTTSWQVLLVVVITSIVLWCFDYGLGWL  140
               T +GK  +   ++AR E+R+V WPT+QET+ T+  V  V  + S++LW  D  L  L
Sbjct  59   ALLTTKGKATVAFAREARTEVRKVIWPTRQETLHTTLIVAAVTAVMSLILWGLDGILVRL  118

Query  141  IKLIIG  146
            +  I G
Sbjct  119  VSFITG  124


>P0AG98 Protein translocase subunit SecE [Escherichia coli O157:H7]
Length=127

 Score = 68.6 bits (166),  Expect = 2e-19
 Identities = 41/126 (33%), Positives = 65/126 (52%), Gaps = 5/126 (4%)

Query  21   SAEVVTSGSPLDVVLWVIALALLIGAAMVNQYLPAYWPPANNIWVRVGVILACIVVALGL  80
            + E   SG  L+ + WV+ +ALL+ A + N        P     +R   ++  I  A G+
Sbjct  4    NTEAQGSGRGLEAMKWVVVVALLLVAIVGNYLYRDIMLP-----LRALAVVILIAAAGGV  58

Query  81   LYATHQGKGFIRLLKDARIELRRVTWPTKQETVTTSWQVLLVVVITSIVLWCFDYGLGWL  140
               T +GK  +   ++AR E+R+V WPT+QET+ T+  V  V  + S++LW  D  L  L
Sbjct  59   ALLTTKGKATVAFAREARTEVRKVIWPTRQETLHTTLIVAAVTAVMSLILWGLDGILVRL  118

Query  141  IKLIIG  146
            +  I G
Sbjct  119  VSFITG  124


>P0AG96 Protein translocase subunit SecE [Escherichia coli (strain 
K12)]
Length=127

 Score = 68.6 bits (166),  Expect = 2e-19
 Identities = 41/126 (33%), Positives = 65/126 (52%), Gaps = 5/126 (4%)

Query  21   SAEVVTSGSPLDVVLWVIALALLIGAAMVNQYLPAYWPPANNIWVRVGVILACIVVALGL  80
            + E   SG  L+ + WV+ +ALL+ A + N        P     +R   ++  I  A G+
Sbjct  4    NTEAQGSGRGLEAMKWVVVVALLLVAIVGNYLYRDIMLP-----LRALAVVILIAAAGGV  58

Query  81   LYATHQGKGFIRLLKDARIELRRVTWPTKQETVTTSWQVLLVVVITSIVLWCFDYGLGWL  140
               T +GK  +   ++AR E+R+V WPT+QET+ T+  V  V  + S++LW  D  L  L
Sbjct  59   ALLTTKGKATVAFAREARTEVRKVIWPTRQETLHTTLIVAAVTAVMSLILWGLDGILVRL  118

Query  141  IKLIIG  146
            +  I G
Sbjct  119  VSFITG  124


>P0A2D3 Protein translocase subunit SecE [Salmonella typhimurium 
(strain LT2 / SGSC1412 / ATCC 700720)]
Length=127

 Score = 66.2 bits (160),  Expect = 1e-18
 Identities = 40/126 (32%), Positives = 63/126 (50%), Gaps = 5/126 (4%)

Query  21   SAEVVTSGSPLDVVLWVIALALLIGAAMVNQYLPAYWPPANNIWVRVGVILACIVVALGL  80
            + E   SG  L+ + W++   LLI A + N        P     +R   ++  I  A G+
Sbjct  4    NTEAQGSGRGLEAMKWIVVAILLIVAIVGNYLYRDMMLP-----LRALAVVILIAAAGGV  58

Query  81   LYATHQGKGFIRLLKDARIELRRVTWPTKQETVTTSWQVLLVVVITSIVLWCFDYGLGWL  140
               T +GK  +   ++AR E+R+V WPT+QET+ T+  V  V  + S++LW  D  L  L
Sbjct  59   ALLTTKGKATVAFAREARTEVRKVIWPTRQETLHTTLIVAAVTAVMSLILWGLDGILVRL  118

Query  141  IKLIIG  146
            +  I G
Sbjct  119  VSFITG  124


>P0A2D4 Protein translocase subunit SecE [Salmonella typhi]
Length=127

 Score = 66.2 bits (160),  Expect = 1e-18
 Identities = 40/126 (32%), Positives = 63/126 (50%), Gaps = 5/126 (4%)

Query  21   SAEVVTSGSPLDVVLWVIALALLIGAAMVNQYLPAYWPPANNIWVRVGVILACIVVALGL  80
            + E   SG  L+ + W++   LLI A + N        P     +R   ++  I  A G+
Sbjct  4    NTEAQGSGRGLEAMKWIVVAILLIVAIVGNYLYRDMMLP-----LRALAVVILIAAAGGV  58

Query  81   LYATHQGKGFIRLLKDARIELRRVTWPTKQETVTTSWQVLLVVVITSIVLWCFDYGLGWL  140
               T +GK  +   ++AR E+R+V WPT+QET+ T+  V  V  + S++LW  D  L  L
Sbjct  59   ALLTTKGKATVAFAREARTEVRKVIWPTRQETLHTTLIVAAVTAVMSLILWGLDGILVRL  118

Query  141  IKLIIG  146
            +  I G
Sbjct  119  VSFITG  124


>Q8KA64 Protein translocase subunit SecE [Buchnera aphidicola 
subsp. Schizaphis graminum (strain Sg)]
Length=127

 Score = 53.1 bits (126),  Expect = 1e-13
 Identities = 27/115 (23%), Positives = 58/115 (50%), Gaps = 5/115 (4%)

Query  31   LDVVLWVIALALLIGAAMVNQYLPAYWPPANNIWVRVGVILACIVVALGLLYATHQGKGF  90
            L+ + W    A+ I +  +N +           + R+ +I   +V A+ +   T + K  
Sbjct  14   LEKIKWFFITAIFITSFFINNFFDKI-----GYFTRISIITLLVVFAISIALYTKKVKNV  68

Query  91   IRLLKDARIELRRVTWPTKQETVTTSWQVLLVVVITSIVLWCFDYGLGWLIKLII  145
               +  ++ E++++TWP  +ET+ T++ ++ V ++ S++LW  D  +  LI  II
Sbjct  69   FVYINASKNEMKKITWPQYKETLYTTFIIISVTILISLLLWGLDSIIFRLIAFII  123


>P43805 Protein translocase subunit SecE [Haemophilus influenzae 
(strain ATCC 51907 / DSM 11121 / KW20 / Rd)]
Length=106

 Score = 45.8 bits (107),  Expect = 5e-11
 Identities = 25/79 (32%), Positives = 40/79 (51%), Gaps = 0/79 (0%)

Query  56   YWPPANNIWVRVGVILACIVVALGLLYATHQGKGFIRLLKDARIELRRVTWPTKQETVTT  115
            Y+    ++ +RV  +   +V+A  L   T+QG        D+R E R+V WPT+ E   T
Sbjct  13   YFQQIYSLPIRVIGMAIALVIAFILAAITNQGTKARAFFNDSRTEARKVVWPTRAEARQT  72

Query  116  SWQVLLVVVITSIVLWCFD  134
            +  V+ V +I S+  W  D
Sbjct  73   TLIVIGVTMIASLFFWAVD  91


>P38382 Protein translocase subunit SecE [Synechocystis sp. (strain 
PCC 6803 / Kazusa)]
Length=81

 Score = 43.1 bits (100),  Expect = 3e-10
 Identities = 20/53 (38%), Positives = 33/53 (62%), Gaps = 3/53 (6%)

Query  90   FIRLLKDARIELRRVTWPTKQETVTTSWQVLLVVVITSIVLWCFDYGLGWLIK  142
            FI   KD   EL +V WP++Q+ ++ S  V+L+V++ S V++  D   GW+ K
Sbjct  26   FIAATKD---ELAKVVWPSRQQLISESVAVILMVILVSTVIYFVDQIFGWITK  75


 Score = 17.7 bits (34),  Expect = 0.56
 Identities = 8/46 (17%), Positives = 19/46 (41%), Gaps = 0/46 (0%)

Query  46  AAMVNQYLPAYWPPANNIWVRVGVILACIVVALGLLYATHQGKGFI  91
           AA  ++     WP    +      ++  +++   ++Y   Q  G+I
Sbjct  28  AATKDELAKVVWPSRQQLISESVAVILMVILVSTVIYFVDQIFGWI  73


>P38383 Protein translocase subunit SecE [Thermus thermophilus 
(strain ATCC 27634 / DSM 579 / HB8)]
Length=60

 Score = 42.4 bits (98),  Expect = 4e-10
 Identities = 20/54 (37%), Positives = 33/54 (61%), Gaps = 0/54 (0%)

Query  91   IRLLKDARIELRRVTWPTKQETVTTSWQVLLVVVITSIVLWCFDYGLGWLIKLI  144
            IR  ++AR EL RVTWPT+++ V  +  +LL  +   ++L  +D    +LI L+
Sbjct  6    IRYFQEARAELARVTWPTREQVVEGTQAILLFTLAFMVILGLYDTVFRFLIGLL  59


>O51356 Protein translocase subunit SecE [Borreliella burgdorferi 
(strain ATCC 35210 / DSM 4680 / CIP 102532 / B31)]
Length=56

 Score = 40.0 bits (92),  Expect = 3e-09
 Identities = 19/44 (43%), Positives = 26/44 (59%), Gaps = 0/44 (0%)

Query  92   RLLKDARIELRRVTWPTKQETVTTSWQVLLVVVITSIVLWCFDY  135
            R +KD+ +EL++VTWP   E V    QV  +V+  SI L   DY
Sbjct  3    RFIKDSILELKKVTWPKYNEVVGNGKQVFWLVLFVSIFLGIVDY  46


>P38381 Protein translocase subunit SecE [Bacillus licheniformis]
Length=59

 Score = 39.3 bits (90),  Expect = 6e-09
 Identities = 19/57 (33%), Positives = 32/57 (56%), Gaps = 0/57 (0%)

Query  89   GFIRLLKDARIELRRVTWPTKQETVTTSWQVLLVVVITSIVLWCFDYGLGWLIKLII  145
            G I+ LK+   E+++VTWP  +E    +  V+  V+  +I     D G+  LI+LI+
Sbjct  2    GIIKFLKNVGKEMKKVTWPKGKELTRYTITVITTVIFFAIFFALIDSGITQLIRLIV  58


>P36691 Protein translocase subunit SecE [Streptomyces virginiae]
Length=93

 Score = 36.6 bits (83),  Expect = 1e-07
 Identities = 17/47 (36%), Positives = 27/47 (57%), Gaps = 0/47 (0%)

Query  100  ELRRVTWPTKQETVTTSWQVLLVVVITSIVLWCFDYGLGWLIKLIIG  146
            ELR+V WPT+ +  T +  V++ VVI   ++   D+G    IK + G
Sbjct  47   ELRKVVWPTRNQLTTYTTVVIVFVVIMIGLVTVIDFGFEKAIKFVFG  93


 Score = 22.7 bits (47),  Expect = 0.011
 Identities = 7/25 (28%), Positives = 14/25 (56%), Gaps = 0/25 (0%)

Query  57  WPPANNIWVRVGVILACIVVALGLL  81
           WP  N +     V++  +V+ +GL+
Sbjct  53  WPTRNQLTTYTTVVIVFVVIMIGLV  77


>D0VWU4 Protein translocase subunit SecE [Aquifex aeolicus (strain 
VF5)]
Length=65

 Score = 35.8 bits (81),  Expect = 1e-07
 Identities = 16/52 (31%), Positives = 27/52 (52%), Gaps = 0/52 (0%)

Query  94   LKDARIELRRVTWPTKQETVTTSWQVLLVVVITSIVLWCFDYGLGWLIKLII  145
            LK  R EL+RV WP+++  V  +  V++  +   + LW  D     +I  I+
Sbjct  8    LKGVRDELKRVVWPSRELVVKATISVIIFSLAIGVYLWILDLTFTKIISFIL  59


>P0A4G8 Protein translocase subunit SecE [Streptomyces coelicolor 
(strain ATCC BAA-471 / A3(2) / M145)]
Length=94

 Score = 35.8 bits (81),  Expect = 2e-07
 Identities = 16/47 (34%), Positives = 26/47 (55%), Gaps = 0/47 (0%)

Query  100  ELRRVTWPTKQETVTTSWQVLLVVVITSIVLWCFDYGLGWLIKLIIG  146
            ELR+V WP++ +  T +  V++ VVI   ++   DYG     K + G
Sbjct  48   ELRKVVWPSRNQLTTYTTVVIIFVVIMIGLVTLIDYGFSHAAKYVFG  94


 Score = 22.3 bits (46),  Expect = 0.015
 Identities = 7/25 (28%), Positives = 14/25 (56%), Gaps = 0/25 (0%)

Query  57  WPPANNIWVRVGVILACIVVALGLL  81
           WP  N +     V++  +V+ +GL+
Sbjct  54  WPSRNQLTTYTTVVIIFVVIMIGLV  78


>P36690 Protein translocase subunit SecE [Streptomyces griseus]
Length=95

 Score = 35.0 bits (79),  Expect = 4e-07
 Identities = 15/47 (32%), Positives = 27/47 (57%), Gaps = 0/47 (0%)

Query  100  ELRRVTWPTKQETVTTSWQVLLVVVITSIVLWCFDYGLGWLIKLIIG  146
            ELR+V WPT+ +  T +  V++ VV+   ++   D G   ++K + G
Sbjct  49   ELRKVVWPTRSQLTTYTSVVIVFVVVMIGLVTVLDIGFARVVKYVFG  95


 Score = 24.3 bits (51),  Expect = 0.003
 Identities = 12/39 (31%), Positives = 21/39 (54%), Gaps = 2/39 (5%)

Query  57  WPPANNIWVRVGVILACIVVALGLLYATHQGKGFIRLLK  95
           WP  + +     V++  +VV +GL+  T    GF R++K
Sbjct  55  WPTRSQLTTYTSVVIVFVVVMIGLV--TVLDIGFARVVK  91



Lambda      K        H        a         alpha
   0.328    0.141    0.459    0.792     4.96 

Gapped
Lambda      K        H        a         alpha    sigma
   0.267   0.0410    0.140     1.90     42.6     43.6 

Effective search space used: 149292


  Database: 1129b51cd6f38b376077f9b2010c6bc7.SwissProt.fasta
    Posted date:  May 20, 2024  1:23 PM
  Number of letters in database: 1,845
  Number of sequences in database:  18



Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Neighboring words threshold: 11
Window for multiple hits: 40