Comparative Genomics

ACIAD0373 / SwissProt Alignments

BLASTP 2.12.0+


Reference: Stephen F. Altschul, Thomas L. Madden, Alejandro A.
Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J.
Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of
protein database search programs", Nucleic Acids Res. 25:3389-3402.


Reference for composition-based statistics: Alejandro A. Schaffer,
L. Aravind, Thomas L. Madden, Sergei Shavirin, John L. Spouge, Yuri
I. Wolf, Eugene V. Koonin, and Stephen F. Altschul (2001),
"Improving the accuracy of PSI-BLAST protein database searches with
composition-based statistics and other refinements", Nucleic Acids
Res. 29:2994-3005.



Database: 7baad313eb65e5b1c1d92f8a3657bc9f.SwissProt.fasta
           13 sequences; 2,068 total letters



Query= ACIAD0373

Length=176
                                                                      Score     E
Sequences producing significant alignments:                          (Bits)  Value

Q9RGZ1 Na(+)/H(+) antiporter subunit E [Alkalihalophilus pseudofi...  73.6    1e-20
Q52982 Probable K(+)/H(+) antiporter subunit E [Rhizobium melilot...  72.8    2e-20
Q7WY60 Na(+)/H(+) antiporter subunit E [Bacillus subtilis (strain...  70.9    1e-19
Q8CPV2 Na(+)/H(+) antiporter subunit E1 [Staphylococcus epidermid...  70.5    2e-19
Q5HQL4 Na(+)/H(+) antiporter subunit E1 [Staphylococcus epidermid...  70.5    2e-19
Q49W87 Na(+)/H(+) antiporter subunit E1 [Staphylococcus saprophyt...  67.4    2e-18
Q4L4W3 Na(+)/H(+) antiporter subunit E1 [Staphylococcus haemolyti...  66.2    6e-18
Q2YWT8 Na(+)/H(+) antiporter subunit E1 [Staphylococcus aureus (s...  64.7    2e-17
Q2G2H8 Na(+)/H(+) antiporter subunit E1 [Staphylococcus aureus (s...  64.3    3e-17
Q2FIC7 Na(+)/H(+) antiporter subunit E1 [Staphylococcus aureus (s...  64.3    3e-17
A6U055 Na(+)/H(+) antiporter subunit E1 [Staphylococcus aureus (s...  64.3    3e-17
A7X0F8 Na(+)/H(+) antiporter subunit E1 [Staphylococcus aureus (s...  64.3    3e-17
P60690 Na(+)/H(+) antiporter subunit E1 [Staphylococcus aureus]       64.3    3e-17


>Q9RGZ1 Na(+)/H(+) antiporter subunit E [Alkalihalophilus pseudofirmus 
(strain ATCC BAA-2126 / JCM 17055 / OF4)]
Length=158

 Score = 73.6 bits (179),  Expect = 1e-20
 Identities = 41/151 (27%), Positives = 85/151 (56%), Gaps = 3/151 (2%)

Query  16   VSVIIALSWLMLAHSLEFANLLLAILLGVFIPRLVRPFITRTPHIH--WNPAIKLIFIVL  73
            ++++IA+ W+   +S    + L+  ++G+FI  ++R F+    ++   W   IKLI +  
Sbjct  7    LNLVIAVIWVNFQNSYTAVDFLIGYVVGIFILFVLRRFLRFDFYMRRIW-AIIKLISLFF  65

Query  74   WDIVVSNIRVAKLVLGPTEHLHPKWYRVPLETQHEQVNSILAMIITTTPGTVSAGIDQER  133
             +++++NI V K+VL P  ++ P    VP + + +   S+LA +I+ TPGT+S     + 
Sbjct  66   KELILANIDVIKIVLSPKMNIQPGIVAVPTKLKTDWELSLLASLISLTPGTLSMDFSDDN  125

Query  134  GDILVHSLSTENTELDIQEIKNRYEAPLIAI  164
              I +H++   N E  I++I + +E  ++ +
Sbjct  126  KYIYIHAIDVPNKEKMIRDIHDTFERAILEV  156


>Q52982 Probable K(+)/H(+) antiporter subunit E [Rhizobium meliloti 
(strain 1021)]
Length=161

 Score = 72.8 bits (177),  Expect = 2e-20
 Identities = 45/159 (28%), Positives = 81/159 (51%), Gaps = 3/159 (2%)

Query  10   WFPHPFVSVIIALSWLMLAHSLEFANLLLAILLGVFIPRLVRPFITRTPHIH-WNPAIKL  68
            WFP+P +S+ + L WL+L+ S+   +++L +++   +  +          +H W+     
Sbjct  4    WFPYPLLSIALLLMWLLLSQSVTPGSIVLGLVVSTVLAWVTLNLQPARSRLHRWSRIAGF  63

Query  69   IFIVLWDIVVSNIRVAKLVL-GPTEHLHPKWYRVPLETQHEQVNSILAMIITTTPGTVSA  127
            I  V+ D++ SNI V  ++L      ++  +  V L+   E   ++LA ++T TPGT   
Sbjct  64   ILRVVGDVIRSNIAVTLIILRAGRRPVNAGFMTVSLDLDDENALALLACVVTATPGTAWL  123

Query  128  GIDQERGDILVHSLSTENTELDIQEIKNRYEAPLIAIFD  166
              D+ +  +L H L  EN +L  + I  RY A L  IF+
Sbjct  124  EYDRRQKILLFHVLDIENEDLWRKTI-TRYAADLKEIFE  161


>Q7WY60 Na(+)/H(+) antiporter subunit E [Bacillus subtilis (strain 
168)]
Length=158

 Score = 70.9 bits (172),  Expect = 1e-19
 Identities = 41/145 (28%), Positives = 77/145 (53%), Gaps = 3/145 (2%)

Query  16   VSVIIALSWLMLAHSLEFANLLLAILLGVFIPRLVRPFITRTPHIHWN--PAIKLIFIVL  73
            ++V +A  W+ L++S   A  +   +LG+      R F TR  ++ W     IKL FI +
Sbjct  7    LNVFLAFCWMFLSNSPSAAGFITGYILGMLSLFFFRRFFTRQFYL-WKLISIIKLCFIFI  65

Query  74   WDIVVSNIRVAKLVLGPTEHLHPKWYRVPLETQHEQVNSILAMIITTTPGTVSAGIDQER  133
             ++ ++N+ V K VL P  ++ P  +    E   +   ++L+++IT TPGT+   I  +R
Sbjct  66   KELYLANVSVMKSVLSPKLNIRPGIFAFKTELTKDWEITMLSLLITLTPGTLVMDISDDR  125

Query  134  GDILVHSLSTENTELDIQEIKNRYE  158
              + +H++  E+ E  I +I+  +E
Sbjct  126  TILYIHAMDIEDAEKAIFDIRESFE  150


>Q8CPV2 Na(+)/H(+) antiporter subunit E1 [Staphylococcus epidermidis 
(strain ATCC 12228 / FDA PCI 1200)]
Length=159

 Score = 70.5 bits (171),  Expect = 2e-19
 Identities = 40/144 (28%), Positives = 76/144 (53%), Gaps = 1/144 (1%)

Query  16   VSVIIALSWLMLAHSLEFANLLLAILLGVFIPRLVRPFITRTPH-IHWNPAIKLIFIVLW  74
            +++++++ WL++ +S    N +L  +LG+F+  L+   +    + +     I LI   L 
Sbjct  7    INLLVSVIWLLVTNSYTLNNFVLGFILGLFLVYLLHRVLPGQFYLVRIYRIIMLIITFLT  66

Query  75   DIVVSNIRVAKLVLGPTEHLHPKWYRVPLETQHEQVNSILAMIITTTPGTVSAGIDQERG  134
            +++ +N  V K++L P     P ++    E + +    +L+ +IT TPGTV  GI  +R 
Sbjct  67   ELIKANFGVLKIILKPRIENKPGFFVYETELERDWQLVLLSNLITLTPGTVVLGISDDRK  126

Query  135  DILVHSLSTENTELDIQEIKNRYE  158
             I +HS+     E +IQ IK+  E
Sbjct  127  KIYIHSIDFSTKEEEIQNIKSSLE  150


>Q5HQL4 Na(+)/H(+) antiporter subunit E1 [Staphylococcus epidermidis 
(strain ATCC 35984 / RP62A)]
Length=159

 Score = 70.5 bits (171),  Expect = 2e-19
 Identities = 40/144 (28%), Positives = 76/144 (53%), Gaps = 1/144 (1%)

Query  16   VSVIIALSWLMLAHSLEFANLLLAILLGVFIPRLVRPFITRTPH-IHWNPAIKLIFIVLW  74
            +++++++ WL++ +S    N +L  +LG+F+  L+   +    + +     I LI   L 
Sbjct  7    INLLVSVIWLLVTNSYTLNNFVLGFILGLFLVYLLHRVLPGQFYLVRIYRIIMLIITFLT  66

Query  75   DIVVSNIRVAKLVLGPTEHLHPKWYRVPLETQHEQVNSILAMIITTTPGTVSAGIDQERG  134
            +++ +N  V K++L P     P ++    E + +    +L+ +IT TPGTV  GI  +R 
Sbjct  67   ELIKANFGVLKIILKPRIENKPGFFVYETELERDWQLVLLSNLITLTPGTVVLGISDDRK  126

Query  135  DILVHSLSTENTELDIQEIKNRYE  158
             I +HS+     E +IQ IK+  E
Sbjct  127  KIYIHSIDFSTKEEEIQNIKSSLE  150


>Q49W87 Na(+)/H(+) antiporter subunit E1 [Staphylococcus saprophyticus 
subsp. saprophyticus (strain ATCC 15305 / DSM 20229 
/ NCIMB 8711 / NCTC 7292 / S-41)]
Length=160

 Score = 67.4 bits (163),  Expect = 2e-18
 Identities = 39/144 (27%), Positives = 75/144 (52%), Gaps = 1/144 (1%)

Query  16   VSVIIALSWLMLAHSLEFANLLLAILLGVFIPRLVRPFIT-RTPHIHWNPAIKLIFIVLW  74
            V++I+++ WL +  S  F N +L  L  + +  ++R  +  R   I     IKL  + L 
Sbjct  7    VNLILSVFWLFVTGSYNFNNFILGYLFALLLVYIMRGVLPGRFYLITVYKIIKLFLVFLI  66

Query  75   DIVVSNIRVAKLVLGPTEHLHPKWYRVPLETQHEQVNSILAMIITTTPGTVSAGIDQERG  134
            +++ +NI V ++V+ P     P ++    + + +    +L+ +IT TPGT+  GI  +R 
Sbjct  67   ELIKANIDVIRIVVKPNIDNEPAFFTYNTDLKKDWQIVLLSNLITLTPGTIVLGISDDRT  126

Query  135  DILVHSLSTENTELDIQEIKNRYE  158
             I +HS+     E +++ IK+  E
Sbjct  127  KIYIHSIDFSTKEEEVESIKSSLE  150


>Q4L4W3 Na(+)/H(+) antiporter subunit E1 [Staphylococcus haemolyticus 
(strain JCSC1435)]
Length=159

 Score = 66.2 bits (160),  Expect = 6e-18
 Identities = 47/146 (32%), Positives = 75/146 (51%), Gaps = 5/146 (3%)

Query  16   VSVIIALSWLMLAHSLEFANLLLAILLGV-FIPRLVRPFITRTPHIHWNPAIKLIFIVLW  74
            ++ I+A  W+ L+ S    NLLL  +LG+ F+    R    R   I     +KL  +   
Sbjct  7    LNFILAFIWIFLSGSYTLNNLLLGFILGLGFVYLFSRILPGRFYFIKIYKILKLAVVFFV  66

Query  75   DIVVSNIRVAKLVLGPTEHLHPKW--YRVPLETQHEQVNSILAMIITTTPGTVSAGIDQE  132
            +++ +NI V K+VL P     P +  Y   L+T  + V  +L+ +IT TPGTV  GI  +
Sbjct  67   ELLKANIDVLKIVLQPKLKNEPGFFVYHTDLKTDWQIV--LLSNLITLTPGTVVLGISDD  124

Query  133  RGDILVHSLSTENTELDIQEIKNRYE  158
            R  I +HS+     E +++ IK+  E
Sbjct  125  RKKIYIHSIDFSTKEEEVEGIKSSLE  150


>Q2YWT8 Na(+)/H(+) antiporter subunit E1 [Staphylococcus aureus 
(strain bovine RF122 / ET3-1)]
Length=159

 Score = 64.7 bits (156),  Expect = 2e-17
 Identities = 39/144 (27%), Positives = 74/144 (51%), Gaps = 1/144 (1%)

Query  16   VSVIIALSWLMLAHSLEFANLLLAILLGVFIPRLVRPFIT-RTPHIHWNPAIKLIFIVLW  74
            ++ IIA+ WL + +S    N +L  + G+ +  L+   +  R   I     IKLI I L 
Sbjct  7    LNFIIAVFWLFVTNSYTTNNFVLGFIFGLVLVYLLHRVLPGRFYVITLYRIIKLIIIFLI  66

Query  75   DIVVSNIRVAKLVLGPTEHLHPKWYRVPLETQHEQVNSILAMIITTTPGTVSAGIDQERG  134
            +++ +N  V K+++ P+    P ++    + + +    +L+ +IT TPGTV  G+  +R 
Sbjct  67   ELIKANFDVLKIIIKPSIKNEPGFFVYHTDLKKDWQIVLLSNLITLTPGTVVLGVSDDRT  126

Query  135  DILVHSLSTENTELDIQEIKNRYE  158
             I +H++     E +++ IK   E
Sbjct  127  KIYIHAIDFSTKEQEVESIKTSLE  150


>Q2G2H8 Na(+)/H(+) antiporter subunit E1 [Staphylococcus aureus 
(strain NCTC 8325 / PS 47)]
Length=159

 Score = 64.3 bits (155),  Expect = 3e-17
 Identities = 38/144 (26%), Positives = 74/144 (51%), Gaps = 1/144 (1%)

Query  16   VSVIIALSWLMLAHSLEFANLLLAILLGVFIPRLVRPFIT-RTPHIHWNPAIKLIFIVLW  74
            ++ IIA+ WL + +S    N +L  + G+ +  L+   +  R   I     IKL+ I L 
Sbjct  7    LNFIIAVFWLFVTNSYTTNNFVLGFIFGLVLVYLLHRVLPGRFYVITLYRIIKLVIIFLI  66

Query  75   DIVVSNIRVAKLVLGPTEHLHPKWYRVPLETQHEQVNSILAMIITTTPGTVSAGIDQERG  134
            +++ +N  V K+++ P+    P ++    + + +    +L+ +IT TPGTV  G+  +R 
Sbjct  67   ELIKANFDVLKIIIKPSIKNEPGFFVYHTDLKKDWQIVLLSNLITLTPGTVVLGVSDDRT  126

Query  135  DILVHSLSTENTELDIQEIKNRYE  158
             I +H++     E +++ IK   E
Sbjct  127  KIYIHAIDFSTKEQEVESIKTSLE  150


>Q2FIC7 Na(+)/H(+) antiporter subunit E1 [Staphylococcus aureus 
(strain USA300)]
Length=159

 Score = 64.3 bits (155),  Expect = 3e-17
 Identities = 38/144 (26%), Positives = 74/144 (51%), Gaps = 1/144 (1%)

Query  16   VSVIIALSWLMLAHSLEFANLLLAILLGVFIPRLVRPFIT-RTPHIHWNPAIKLIFIVLW  74
            ++ IIA+ WL + +S    N +L  + G+ +  L+   +  R   I     IKL+ I L 
Sbjct  7    LNFIIAVFWLFVTNSYTTNNFVLGFIFGLVLVYLLHRVLPGRFYVITLYRIIKLVIIFLI  66

Query  75   DIVVSNIRVAKLVLGPTEHLHPKWYRVPLETQHEQVNSILAMIITTTPGTVSAGIDQERG  134
            +++ +N  V K+++ P+    P ++    + + +    +L+ +IT TPGTV  G+  +R 
Sbjct  67   ELIKANFDVLKIIIKPSIKNEPGFFVYHTDLKKDWQIVLLSNLITLTPGTVVLGVSDDRT  126

Query  135  DILVHSLSTENTELDIQEIKNRYE  158
             I +H++     E +++ IK   E
Sbjct  127  KIYIHAIDFSTKEQEVESIKTSLE  150


>A6U055 Na(+)/H(+) antiporter subunit E1 [Staphylococcus aureus 
(strain JH1)]
Length=159

 Score = 64.3 bits (155),  Expect = 3e-17
 Identities = 38/144 (26%), Positives = 74/144 (51%), Gaps = 1/144 (1%)

Query  16   VSVIIALSWLMLAHSLEFANLLLAILLGVFIPRLVRPFIT-RTPHIHWNPAIKLIFIVLW  74
            ++ IIA+ WL + +S    N +L  + G+ +  L+   +  R   I     IKL+ I L 
Sbjct  7    LNFIIAVFWLFVTNSYTTNNFVLGFIFGLVLVYLLHRVLPGRFYVITLYRIIKLVIIFLI  66

Query  75   DIVVSNIRVAKLVLGPTEHLHPKWYRVPLETQHEQVNSILAMIITTTPGTVSAGIDQERG  134
            +++ +N  V K+++ P+    P ++    + + +    +L+ +IT TPGTV  G+  +R 
Sbjct  67   ELIKANFDVLKIIIKPSIKNEPGFFVYHTDLKKDWQIVLLSNLITLTPGTVVLGVSDDRT  126

Query  135  DILVHSLSTENTELDIQEIKNRYE  158
             I +H++     E +++ IK   E
Sbjct  127  KIYIHAIDFSTKEQEVESIKTSLE  150


>A7X0F8 Na(+)/H(+) antiporter subunit E1 [Staphylococcus aureus 
(strain Mu3 / ATCC 700698)]
Length=159

 Score = 64.3 bits (155),  Expect = 3e-17
 Identities = 38/144 (26%), Positives = 74/144 (51%), Gaps = 1/144 (1%)

Query  16   VSVIIALSWLMLAHSLEFANLLLAILLGVFIPRLVRPFIT-RTPHIHWNPAIKLIFIVLW  74
            ++ IIA+ WL + +S    N +L  + G+ +  L+   +  R   I     IKL+ I L 
Sbjct  7    LNFIIAVFWLFVTNSYTTNNFVLGFIFGLVLVYLLHRVLPGRFYVITLYRIIKLVIIFLI  66

Query  75   DIVVSNIRVAKLVLGPTEHLHPKWYRVPLETQHEQVNSILAMIITTTPGTVSAGIDQERG  134
            +++ +N  V K+++ P+    P ++    + + +    +L+ +IT TPGTV  G+  +R 
Sbjct  67   ELIKANFDVLKIIIKPSIKNEPGFFVYHTDLKKDWQIVLLSNLITLTPGTVVLGVSDDRT  126

Query  135  DILVHSLSTENTELDIQEIKNRYE  158
             I +H++     E +++ IK   E
Sbjct  127  KIYIHAIDFSTKEQEVESIKTSLE  150


>P60690 Na(+)/H(+) antiporter subunit E1 [Staphylococcus aureus]
Length=159

 Score = 64.3 bits (155),  Expect = 3e-17
 Identities = 38/144 (26%), Positives = 74/144 (51%), Gaps = 1/144 (1%)

Query  16   VSVIIALSWLMLAHSLEFANLLLAILLGVFIPRLVRPFIT-RTPHIHWNPAIKLIFIVLW  74
            ++ IIA+ WL + +S    N +L  + G+ +  L+   +  R   I     IKL+ I L 
Sbjct  7    LNFIIAVFWLFVTNSYTTNNFVLGFIFGLVLVYLLHRVLPGRFYVITLYRIIKLVIIFLI  66

Query  75   DIVVSNIRVAKLVLGPTEHLHPKWYRVPLETQHEQVNSILAMIITTTPGTVSAGIDQERG  134
            +++ +N  V K+++ P+    P ++    + + +    +L+ +IT TPGTV  G+  +R 
Sbjct  67   ELIKANFDVLKIIIKPSIKNEPGFFVYHTDLKKDWQIVLLSNLITLTPGTVVLGVSDDRT  126

Query  135  DILVHSLSTENTELDIQEIKNRYE  158
             I +H++     E +++ IK   E
Sbjct  127  KIYIHAIDFSTKEQEVESIKTSLE  150



Lambda      K        H        a         alpha
   0.328    0.142    0.448    0.792     4.96 

Gapped
Lambda      K        H        a         alpha    sigma
   0.267   0.0410    0.140     1.90     42.6     43.6 

Effective search space used: 227433


  Database: 7baad313eb65e5b1c1d92f8a3657bc9f.SwissProt.fasta
    Posted date:  May 9, 2024  8:14 PM
  Number of letters in database: 2,068
  Number of sequences in database:  13



Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Neighboring words threshold: 11
Window for multiple hits: 40