BLASTP 2.12.0+
Reference: Stephen F. Altschul, Thomas L. Madden, Alejandro A.
Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J.
Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of
protein database search programs", Nucleic Acids Res. 25:3389-3402.
Reference for composition-based statistics: Alejandro A. Schaffer,
L. Aravind, Thomas L. Madden, Sergei Shavirin, John L. Spouge, Yuri
I. Wolf, Eugene V. Koonin, and Stephen F. Altschul (2001),
"Improving the accuracy of PSI-BLAST protein database searches with
composition-based statistics and other refinements", Nucleic Acids
Res. 29:2994-3005.
Database: 588db0f3a8ffe78070ad17fd393114c0.SwissProt.fasta
21 sequences; 9,390 total letters
Query= ACIAD0562
Length=431
Score E
Sequences producing significant alignments: (Bits) Value
Q6FEM2 Histidine--tRNA ligase [Acinetobacter baylyi (strain ATCC ... 849 0.0
B0V5G6 Histidine--tRNA ligase [Acinetobacter baumannii (strain AYE)] 762 0.0
B7H068 Histidine--tRNA ligase [Acinetobacter baumannii (strain AB... 762 0.0
B7I5G8 Histidine--tRNA ligase [Acinetobacter baumannii (strain AB... 761 0.0
B0VKR7 Histidine--tRNA ligase [Acinetobacter baumannii (strain SDF)] 757 0.0
B2I3E6 Histidine--tRNA ligase [Acinetobacter baumannii (strain AC... 753 0.0
A3M212 Histidine--tRNA ligase [Acinetobacter baumannii (strain AT... 753 0.0
Q1QD17 Histidine--tRNA ligase [Psychrobacter cryohalolentis (stra... 498 4e-179
A5WGQ0 Histidine--tRNA ligase [Psychrobacter sp. (strain PRwf-1)] 487 2e-174
Q4FTW6 Histidine--tRNA ligase [Psychrobacter arcticus (strain DSM... 487 2e-174
A8GHW4 Histidine--tRNA ligase [Serratia proteamaculans (strain 568)] 464 9e-166
P60906 Histidine--tRNA ligase [Escherichia coli (strain K12)] 457 7e-163
O52765 Histidine--tRNA ligase [Salmonella typhimurium (strain LT2... 455 4e-162
P60911 Histidine--tRNA ligase [Staphylococcus aureus] 304 6e-103
P30053 Histidine--tRNA ligase [Streptococcus dysgalactiae subsp. ... 293 2e-98
P56194 Histidine--tRNA ligase [Thermus thermophilus (strain ATCC ... 268 7e-89
O82413 Histidine--tRNA ligase, chloroplastic/mitochondrial [Arabi... 124 3e-34
Q61035 Histidine--tRNA ligase, cytoplasmic [Mus musculus] 93.2 2e-23
P12081 Histidine--tRNA ligase, cytoplasmic [Homo sapiens] 93.2 2e-23
P70076 Histidine--tRNA ligase, cytoplasmic [Takifugu rubripes] 90.5 1e-22
P49590 Histidine--tRNA ligase, mitochondrial [Homo sapiens] 87.0 2e-21
>Q6FEM2 Histidine--tRNA ligase [Acinetobacter baylyi (strain ATCC
33305 / BD413 / ADP1)]
Length=430
Score = 849 bits (2194), Expect = 0.0
Identities = 430/430 (100%), Positives = 430/430 (100%), Gaps = 0/430 (0%)
Query 1 MSSIVAIKGFNDVLPTQTAAWRRLEQHLASLMDAYGYQQIRLPIVEQTGLFKRAIGDATD 60
MSSIVAIKGFNDVLPTQTAAWRRLEQHLASLMDAYGYQQIRLPIVEQTGLFKRAIGDATD
Sbjct 1 MSSIVAIKGFNDVLPTQTAAWRRLEQHLASLMDAYGYQQIRLPIVEQTGLFKRAIGDATD 60
Query 61 IVEKEMYTFFDKGTPPESLTLRPEGTAGCVRAMLEHNLLRGATPRVWYVGPMFRYEKPQK 120
IVEKEMYTFFDKGTPPESLTLRPEGTAGCVRAMLEHNLLRGATPRVWYVGPMFRYEKPQK
Sbjct 61 IVEKEMYTFFDKGTPPESLTLRPEGTAGCVRAMLEHNLLRGATPRVWYVGPMFRYEKPQK 120
Query 121 GRYRQFHQFGVETFGVATPDIDAELILMTARLWKRMGVSEKVQLELNTLGEIDERAAYRT 180
GRYRQFHQFGVETFGVATPDIDAELILMTARLWKRMGVSEKVQLELNTLGEIDERAAYRT
Sbjct 121 GRYRQFHQFGVETFGVATPDIDAELILMTARLWKRMGVSEKVQLELNTLGEIDERAAYRT 180
Query 181 ALVEFLTQHKEALDEDSQRRLGTNPLRILDSKVESTQKILENAPKLHDFLQEDSLAHFNQ 240
ALVEFLTQHKEALDEDSQRRLGTNPLRILDSKVESTQKILENAPKLHDFLQEDSLAHFNQ
Sbjct 181 ALVEFLTQHKEALDEDSQRRLGTNPLRILDSKVESTQKILENAPKLHDFLQEDSLAHFNQ 240
Query 241 LQEYLTHAGVSFVINQKLVRGLDYYNKTVFEWTTTALGSQGTVCAGGRYDGLVGQLKGKA 300
LQEYLTHAGVSFVINQKLVRGLDYYNKTVFEWTTTALGSQGTVCAGGRYDGLVGQLKGKA
Sbjct 241 LQEYLTHAGVSFVINQKLVRGLDYYNKTVFEWTTTALGSQGTVCAGGRYDGLVGQLKGKA 300
Query 301 DQSVPAVGFAMGMERLLLLLEQVEQAEVVRDCDVFLVAESAFQGHALVLAEQIRDQFEGL 360
DQSVPAVGFAMGMERLLLLLEQVEQAEVVRDCDVFLVAESAFQGHALVLAEQIRDQFEGL
Sbjct 301 DQSVPAVGFAMGMERLLLLLEQVEQAEVVRDCDVFLVAESAFQGHALVLAEQIRDQFEGL 360
Query 361 ASTIRVKTGSQGSMKSQMKKADQSGAHYAVILGEREWTTQELTVKELATSEQSQVAISEL 420
ASTIRVKTGSQGSMKSQMKKADQSGAHYAVILGEREWTTQELTVKELATSEQSQVAISEL
Sbjct 361 ASTIRVKTGSQGSMKSQMKKADQSGAHYAVILGEREWTTQELTVKELATSEQSQVAISEL 420
Query 421 VPFLVKKFEK 430
VPFLVKKFEK
Sbjct 421 VPFLVKKFEK 430
>B0V5G6 Histidine--tRNA ligase [Acinetobacter baumannii (strain
AYE)]
Length=430
Score = 762 bits (1968), Expect = 0.0
Identities = 377/430 (88%), Positives = 402/430 (93%), Gaps = 0/430 (0%)
Query 1 MSSIVAIKGFNDVLPTQTAAWRRLEQHLASLMDAYGYQQIRLPIVEQTGLFKRAIGDATD 60
MSSIVAIKGFNDVLPTQTAAWRRLEQHLASLMDAYGYQQIRLPIVEQTGLFKRAIGDATD
Sbjct 1 MSSIVAIKGFNDVLPTQTAAWRRLEQHLASLMDAYGYQQIRLPIVEQTGLFKRAIGDATD 60
Query 61 IVEKEMYTFFDKGTPPESLTLRPEGTAGCVRAMLEHNLLRGATPRVWYVGPMFRYEKPQK 120
IVEKEMYTFFDKG PPESLTLRPEGTAGCVRA++EHNLLRGATPRVWY+GPMFRYEKPQK
Sbjct 61 IVEKEMYTFFDKGNPPESLTLRPEGTAGCVRALVEHNLLRGATPRVWYMGPMFRYEKPQK 120
Query 121 GRYRQFHQFGVETFGVATPDIDAELILMTARLWKRMGVSEKVQLELNTLGEIDERAAYRT 180
GRYRQFHQFGVETFGVATPDIDAELI++TARLWKRMGV VQLELNTLGE DER YR
Sbjct 121 GRYRQFHQFGVETFGVATPDIDAELIMLTARLWKRMGVDHMVQLELNTLGETDERTEYRN 180
Query 181 ALVEFLTQHKEALDEDSQRRLGTNPLRILDSKVESTQKILENAPKLHDFLQEDSLAHFNQ 240
ALV FL +HK+ALDEDSQRRL TNPLRILDSK+ESTQKILENAPKLHDFL+EDSL+HF Q
Sbjct 181 ALVAFLNEHKDALDEDSQRRLTTNPLRILDSKIESTQKILENAPKLHDFLKEDSLSHFQQ 240
Query 241 LQEYLTHAGVSFVINQKLVRGLDYYNKTVFEWTTTALGSQGTVCAGGRYDGLVGQLKGKA 300
LQ+YLT AG+ FVINQKLVRGLDYYNKTVFEWTTTALGSQGTVCAGGRYDGLVGQLKGKA
Sbjct 241 LQDYLTAAGIKFVINQKLVRGLDYYNKTVFEWTTTALGSQGTVCAGGRYDGLVGQLKGKA 300
Query 301 DQSVPAVGFAMGMERLLLLLEQVEQAEVVRDCDVFLVAESAFQGHALVLAEQIRDQFEGL 360
DQSVPAVGFAMGMERLLLLLEQVEQAE+VRDC+ FLVAE A+Q ALVLAEQ+RDQ E
Sbjct 301 DQSVPAVGFAMGMERLLLLLEQVEQAEIVRDCEAFLVAEPAYQSKALVLAEQLRDQLEAA 360
Query 361 ASTIRVKTGSQGSMKSQMKKADQSGAHYAVILGEREWTTQELTVKELATSEQSQVAISEL 420
S IR+KTGSQGSMKSQMKKADQ+GA YA+ILGEREW Q+L VKELAT+EQSQVA++EL
Sbjct 361 NSNIRIKTGSQGSMKSQMKKADQAGAVYAIILGEREWEAQQLAVKELATAEQSQVALAEL 420
Query 421 VPFLVKKFEK 430
VPFL++KF K
Sbjct 421 VPFLIEKFTK 430
>B7H068 Histidine--tRNA ligase [Acinetobacter baumannii (strain
AB307-0294)]
Length=430
Score = 762 bits (1968), Expect = 0.0
Identities = 377/430 (88%), Positives = 402/430 (93%), Gaps = 0/430 (0%)
Query 1 MSSIVAIKGFNDVLPTQTAAWRRLEQHLASLMDAYGYQQIRLPIVEQTGLFKRAIGDATD 60
MSSIVAIKGFNDVLPTQTAAWRRLEQHLASLMDAYGYQQIRLPIVEQTGLFKRAIGDATD
Sbjct 1 MSSIVAIKGFNDVLPTQTAAWRRLEQHLASLMDAYGYQQIRLPIVEQTGLFKRAIGDATD 60
Query 61 IVEKEMYTFFDKGTPPESLTLRPEGTAGCVRAMLEHNLLRGATPRVWYVGPMFRYEKPQK 120
IVEKEMYTFFDKG PPESLTLRPEGTAGCVRA++EHNLLRGATPRVWY+GPMFRYEKPQK
Sbjct 61 IVEKEMYTFFDKGNPPESLTLRPEGTAGCVRALVEHNLLRGATPRVWYMGPMFRYEKPQK 120
Query 121 GRYRQFHQFGVETFGVATPDIDAELILMTARLWKRMGVSEKVQLELNTLGEIDERAAYRT 180
GRYRQFHQFGVETFGVATPDIDAELI++TARLWKRMGV VQLELNTLGE DER YR
Sbjct 121 GRYRQFHQFGVETFGVATPDIDAELIMLTARLWKRMGVDHMVQLELNTLGETDERTEYRN 180
Query 181 ALVEFLTQHKEALDEDSQRRLGTNPLRILDSKVESTQKILENAPKLHDFLQEDSLAHFNQ 240
ALV FL +HK+ALDEDSQRRL TNPLRILDSK+ESTQKILENAPKLHDFL+EDSL+HF Q
Sbjct 181 ALVAFLNEHKDALDEDSQRRLTTNPLRILDSKIESTQKILENAPKLHDFLKEDSLSHFQQ 240
Query 241 LQEYLTHAGVSFVINQKLVRGLDYYNKTVFEWTTTALGSQGTVCAGGRYDGLVGQLKGKA 300
LQ+YLT AG+ FVINQKLVRGLDYYNKTVFEWTTTALGSQGTVCAGGRYDGLVGQLKGKA
Sbjct 241 LQDYLTAAGIKFVINQKLVRGLDYYNKTVFEWTTTALGSQGTVCAGGRYDGLVGQLKGKA 300
Query 301 DQSVPAVGFAMGMERLLLLLEQVEQAEVVRDCDVFLVAESAFQGHALVLAEQIRDQFEGL 360
DQSVPAVGFAMGMERLLLLLEQVEQAE+VRDC+ FLVAE A+Q ALVLAEQ+RDQ E
Sbjct 301 DQSVPAVGFAMGMERLLLLLEQVEQAEIVRDCEAFLVAEPAYQSKALVLAEQLRDQLEAA 360
Query 361 ASTIRVKTGSQGSMKSQMKKADQSGAHYAVILGEREWTTQELTVKELATSEQSQVAISEL 420
S IR+KTGSQGSMKSQMKKADQ+GA YA+ILGEREW Q+L VKELAT+EQSQVA++EL
Sbjct 361 NSNIRIKTGSQGSMKSQMKKADQAGAVYAIILGEREWEAQQLAVKELATAEQSQVALAEL 420
Query 421 VPFLVKKFEK 430
VPFL++KF K
Sbjct 421 VPFLIEKFTK 430
>B7I5G8 Histidine--tRNA ligase [Acinetobacter baumannii (strain
AB0057)]
Length=430
Score = 761 bits (1964), Expect = 0.0
Identities = 376/430 (87%), Positives = 402/430 (93%), Gaps = 0/430 (0%)
Query 1 MSSIVAIKGFNDVLPTQTAAWRRLEQHLASLMDAYGYQQIRLPIVEQTGLFKRAIGDATD 60
MSSIVAIKGFNDVLPTQTAAWRRLEQHLASLMDAYGYQQIRLPIVEQTGLFKRAIGDATD
Sbjct 1 MSSIVAIKGFNDVLPTQTAAWRRLEQHLASLMDAYGYQQIRLPIVEQTGLFKRAIGDATD 60
Query 61 IVEKEMYTFFDKGTPPESLTLRPEGTAGCVRAMLEHNLLRGATPRVWYVGPMFRYEKPQK 120
IVEKEMYTFFDKG PPESLTLRPEGTAGCVRA++EHNLLRGATPRVWY+GPMFRYEKPQK
Sbjct 61 IVEKEMYTFFDKGNPPESLTLRPEGTAGCVRALVEHNLLRGATPRVWYMGPMFRYEKPQK 120
Query 121 GRYRQFHQFGVETFGVATPDIDAELILMTARLWKRMGVSEKVQLELNTLGEIDERAAYRT 180
GRYRQFHQFGVETFGVATPDIDAELI++TARLWKRMGV VQLELNTLGE DER YR
Sbjct 121 GRYRQFHQFGVETFGVATPDIDAELIMLTARLWKRMGVDHMVQLELNTLGETDERTEYRN 180
Query 181 ALVEFLTQHKEALDEDSQRRLGTNPLRILDSKVESTQKILENAPKLHDFLQEDSLAHFNQ 240
ALV FL +HK+ALDEDSQRRL TNPLRILDSK+ESTQKILENAPKLHDFL+E+SL+HF Q
Sbjct 181 ALVAFLNEHKDALDEDSQRRLTTNPLRILDSKIESTQKILENAPKLHDFLKEESLSHFQQ 240
Query 241 LQEYLTHAGVSFVINQKLVRGLDYYNKTVFEWTTTALGSQGTVCAGGRYDGLVGQLKGKA 300
LQ+YLT AG+ FVINQKLVRGLDYYNKTVFEWTTTALGSQGTVCAGGRYDGLVGQLKGKA
Sbjct 241 LQDYLTAAGIKFVINQKLVRGLDYYNKTVFEWTTTALGSQGTVCAGGRYDGLVGQLKGKA 300
Query 301 DQSVPAVGFAMGMERLLLLLEQVEQAEVVRDCDVFLVAESAFQGHALVLAEQIRDQFEGL 360
DQSVPAVGFAMGMERLLLLLEQVEQAE+VRDC+ FLVAE A+Q ALVLAEQ+RDQ E
Sbjct 301 DQSVPAVGFAMGMERLLLLLEQVEQAEIVRDCEAFLVAEPAYQSKALVLAEQLRDQLEAA 360
Query 361 ASTIRVKTGSQGSMKSQMKKADQSGAHYAVILGEREWTTQELTVKELATSEQSQVAISEL 420
S IR+KTGSQGSMKSQMKKADQ+GA YA+ILGEREW Q+L VKELAT+EQSQVA++EL
Sbjct 361 NSNIRIKTGSQGSMKSQMKKADQAGAVYAIILGEREWEAQQLAVKELATAEQSQVALAEL 420
Query 421 VPFLVKKFEK 430
VPFL++KF K
Sbjct 421 VPFLIEKFTK 430
>B0VKR7 Histidine--tRNA ligase [Acinetobacter baumannii (strain
SDF)]
Length=430
Score = 757 bits (1955), Expect = 0.0
Identities = 375/430 (87%), Positives = 400/430 (93%), Gaps = 0/430 (0%)
Query 1 MSSIVAIKGFNDVLPTQTAAWRRLEQHLASLMDAYGYQQIRLPIVEQTGLFKRAIGDATD 60
MSSIVAIKGFNDVLPTQTAAWRRLEQHLASLMDAYGYQQIRLPIVEQTGLFKRAIGDATD
Sbjct 1 MSSIVAIKGFNDVLPTQTAAWRRLEQHLASLMDAYGYQQIRLPIVEQTGLFKRAIGDATD 60
Query 61 IVEKEMYTFFDKGTPPESLTLRPEGTAGCVRAMLEHNLLRGATPRVWYVGPMFRYEKPQK 120
IVEKEMYTFFDKG PPESLTLRPEGTAGCVRA++EHNLLRGATPRVWY+GPMFRYEKPQK
Sbjct 61 IVEKEMYTFFDKGNPPESLTLRPEGTAGCVRALVEHNLLRGATPRVWYMGPMFRYEKPQK 120
Query 121 GRYRQFHQFGVETFGVATPDIDAELILMTARLWKRMGVSEKVQLELNTLGEIDERAAYRT 180
GRYRQFHQFGVETFGVATPDIDAELI++TARLWKRMGV VQLELNTLGE DER YR
Sbjct 121 GRYRQFHQFGVETFGVATPDIDAELIMLTARLWKRMGVDHMVQLELNTLGETDERTEYRN 180
Query 181 ALVEFLTQHKEALDEDSQRRLGTNPLRILDSKVESTQKILENAPKLHDFLQEDSLAHFNQ 240
ALV FL +HK+ALDEDSQRRL TNPLRILDSK+ESTQKILENAPKLHDFL+EDSL+HF Q
Sbjct 181 ALVAFLNEHKDALDEDSQRRLTTNPLRILDSKIESTQKILENAPKLHDFLKEDSLSHFQQ 240
Query 241 LQEYLTHAGVSFVINQKLVRGLDYYNKTVFEWTTTALGSQGTVCAGGRYDGLVGQLKGKA 300
LQ+YLT AG+ FVINQKLVRGLDYYNKTVFEWTTTALGSQGTVCAGGRYDGLVGQLKGKA
Sbjct 241 LQDYLTAAGIKFVINQKLVRGLDYYNKTVFEWTTTALGSQGTVCAGGRYDGLVGQLKGKA 300
Query 301 DQSVPAVGFAMGMERLLLLLEQVEQAEVVRDCDVFLVAESAFQGHALVLAEQIRDQFEGL 360
DQSVPAVGFAMGMERLLLLLEQVEQAE+VR C+ FLVAE A+Q ALVLAEQ+RDQ E
Sbjct 301 DQSVPAVGFAMGMERLLLLLEQVEQAEIVRHCEAFLVAEPAYQSKALVLAEQLRDQLEAA 360
Query 361 ASTIRVKTGSQGSMKSQMKKADQSGAHYAVILGEREWTTQELTVKELATSEQSQVAISEL 420
S IR+KTGSQ SMKSQMKKADQ+GA YA+ILGEREW Q+L VKELAT+EQSQVA++EL
Sbjct 361 NSNIRIKTGSQSSMKSQMKKADQAGAVYAIILGEREWEAQQLAVKELATAEQSQVALAEL 420
Query 421 VPFLVKKFEK 430
VPFL++KF K
Sbjct 421 VPFLIEKFTK 430
>B2I3E6 Histidine--tRNA ligase [Acinetobacter baumannii (strain
ACICU)]
Length=430
Score = 753 bits (1945), Expect = 0.0
Identities = 372/430 (87%), Positives = 401/430 (93%), Gaps = 0/430 (0%)
Query 1 MSSIVAIKGFNDVLPTQTAAWRRLEQHLASLMDAYGYQQIRLPIVEQTGLFKRAIGDATD 60
MSSIVAIKGFNDVLPTQTAAWRRLEQHLASLMDAYGYQQIRLPIVEQTGLFKRAIGDATD
Sbjct 1 MSSIVAIKGFNDVLPTQTAAWRRLEQHLASLMDAYGYQQIRLPIVEQTGLFKRAIGDATD 60
Query 61 IVEKEMYTFFDKGTPPESLTLRPEGTAGCVRAMLEHNLLRGATPRVWYVGPMFRYEKPQK 120
IVEKEMYTFFDKG PPESLTLRPEGTAGCVRA++EHNLLRGATPRVWY+GPMFRYEKPQK
Sbjct 61 IVEKEMYTFFDKGNPPESLTLRPEGTAGCVRALVEHNLLRGATPRVWYMGPMFRYEKPQK 120
Query 121 GRYRQFHQFGVETFGVATPDIDAELILMTARLWKRMGVSEKVQLELNTLGEIDERAAYRT 180
GRYRQFHQFGVETFGVATPDI+AE+ILMTARLWKRMGV+ VQLELNTLGE +ER YR
Sbjct 121 GRYRQFHQFGVETFGVATPDIEAEVILMTARLWKRMGVAHMVQLELNTLGEKEERTEYRN 180
Query 181 ALVEFLTQHKEALDEDSQRRLGTNPLRILDSKVESTQKILENAPKLHDFLQEDSLAHFNQ 240
ALV FL +HK+ALDEDSQRRL TNPLRILDSK+ESTQKILENAPKL+DFL+EDSL+HF Q
Sbjct 181 ALVAFLNEHKDALDEDSQRRLTTNPLRILDSKIESTQKILENAPKLYDFLKEDSLSHFQQ 240
Query 241 LQEYLTHAGVSFVINQKLVRGLDYYNKTVFEWTTTALGSQGTVCAGGRYDGLVGQLKGKA 300
LQ+YLT AG+ FVINQKLVRGLDYYNKTVFEWTTTALGSQGTVC GGRYDGLVGQLKGKA
Sbjct 241 LQDYLTAAGIKFVINQKLVRGLDYYNKTVFEWTTTALGSQGTVCGGGRYDGLVGQLKGKA 300
Query 301 DQSVPAVGFAMGMERLLLLLEQVEQAEVVRDCDVFLVAESAFQGHALVLAEQIRDQFEGL 360
DQSVPAVGF MGMERLLLL+EQVEQAE+VRDC+ FLVAE A+Q ALVLAEQ+RDQ E
Sbjct 301 DQSVPAVGFGMGMERLLLLIEQVEQAEIVRDCEAFLVAEPAYQSKALVLAEQLRDQLEAA 360
Query 361 ASTIRVKTGSQGSMKSQMKKADQSGAHYAVILGEREWTTQELTVKELATSEQSQVAISEL 420
S IR+KTGSQGSMKSQMKKADQ+GA YA+ILGEREW Q+L VKELAT+EQSQVA++EL
Sbjct 361 NSNIRIKTGSQGSMKSQMKKADQAGAVYAIILGEREWEAQQLAVKELATAEQSQVALAEL 420
Query 421 VPFLVKKFEK 430
VPFL++KF K
Sbjct 421 VPFLIEKFTK 430
>A3M212 Histidine--tRNA ligase [Acinetobacter baumannii (strain
ATCC 17978 / CIP 53.77 / LMG 1025 / NCDC KC755 / 5377)]
Length=430
Score = 753 bits (1944), Expect = 0.0
Identities = 371/430 (86%), Positives = 401/430 (93%), Gaps = 0/430 (0%)
Query 1 MSSIVAIKGFNDVLPTQTAAWRRLEQHLASLMDAYGYQQIRLPIVEQTGLFKRAIGDATD 60
MSSIVAIKGFNDVLPTQTAAWRRLEQHLASLMDAYGYQQIRLPIVEQTGLFKRAIGDATD
Sbjct 1 MSSIVAIKGFNDVLPTQTAAWRRLEQHLASLMDAYGYQQIRLPIVEQTGLFKRAIGDATD 60
Query 61 IVEKEMYTFFDKGTPPESLTLRPEGTAGCVRAMLEHNLLRGATPRVWYVGPMFRYEKPQK 120
IVEKEMYTFFDKG PPESLTLRPEGTAGCVRA++EHNLLRGATPRVWY+GPMFRYEKPQK
Sbjct 61 IVEKEMYTFFDKGNPPESLTLRPEGTAGCVRALVEHNLLRGATPRVWYMGPMFRYEKPQK 120
Query 121 GRYRQFHQFGVETFGVATPDIDAELILMTARLWKRMGVSEKVQLELNTLGEIDERAAYRT 180
GRYRQFHQFGVETFGVATPDI+AE+ILMTARLWKRMGV+ VQLELNTLGE +ER YR
Sbjct 121 GRYRQFHQFGVETFGVATPDIEAEVILMTARLWKRMGVAHMVQLELNTLGEKEERTEYRN 180
Query 181 ALVEFLTQHKEALDEDSQRRLGTNPLRILDSKVESTQKILENAPKLHDFLQEDSLAHFNQ 240
ALV FL +HK+ALDEDSQRRL TNPLRILDSK+ESTQKILENAPKL+DFL+EDSL+HF Q
Sbjct 181 ALVAFLNEHKDALDEDSQRRLTTNPLRILDSKIESTQKILENAPKLYDFLKEDSLSHFQQ 240
Query 241 LQEYLTHAGVSFVINQKLVRGLDYYNKTVFEWTTTALGSQGTVCAGGRYDGLVGQLKGKA 300
LQ+YLT AG+ FVINQKLVRGLDYYNKTVFEWTTTALGSQGTVC GGRYDGLVGQLKGKA
Sbjct 241 LQDYLTAAGIKFVINQKLVRGLDYYNKTVFEWTTTALGSQGTVCGGGRYDGLVGQLKGKA 300
Query 301 DQSVPAVGFAMGMERLLLLLEQVEQAEVVRDCDVFLVAESAFQGHALVLAEQIRDQFEGL 360
DQSVPAVGF MGMERLLLL+EQVEQAE+VRDC+ FLVAE A+Q ALVLAEQ+RDQ E
Sbjct 301 DQSVPAVGFGMGMERLLLLIEQVEQAEIVRDCEAFLVAEPAYQSKALVLAEQLRDQLEAA 360
Query 361 ASTIRVKTGSQGSMKSQMKKADQSGAHYAVILGEREWTTQELTVKELATSEQSQVAISEL 420
S IR+KTGSQGSMKSQMKKADQ+GA YA+ILGEREW Q+L +KELAT+EQSQVA++EL
Sbjct 361 NSNIRIKTGSQGSMKSQMKKADQAGAVYAIILGEREWEAQQLAIKELATAEQSQVALAEL 420
Query 421 VPFLVKKFEK 430
VPFL++KF K
Sbjct 421 VPFLIEKFTK 430
>Q1QD17 Histidine--tRNA ligase [Psychrobacter cryohalolentis (strain
ATCC BAA-1226 / DSM 17306 / VKM B-2378 / K5)]
Length=434
Score = 498 bits (1283), Expect = 4e-179
Identities = 259/423 (61%), Positives = 312/423 (74%), Gaps = 14/423 (3%)
Query 4 IVAIKGFNDVLPTQTAAWRRLEQHLASLMDAYGYQQIRLPIVEQTGLFKRAIGDATDIVE 63
I AIKGFND+LP Q+A W LE LA+++ YGY+ IRLPIVEQT LF RAIG ATDIVE
Sbjct 2 IKAIKGFNDILPAQSAKWLYLESILANVLGRYGYEHIRLPIVEQTDLFARAIGGATDIVE 61
Query 64 KEMYTFFDKGTPPESLTLRPEGTAGCVRAMLEHNLLRGATPRVWYVGPMFRYEKPQKGRY 123
KEMY+F DK PP LTLRPEGTAG VRA+ EHNLLRG TP++WY+GPMFRYE+PQKGRY
Sbjct 62 KEMYSFTDKSDPPTPLTLRPEGTAGAVRAVNEHNLLRGDTPKLWYIGPMFRYERPQKGRY 121
Query 124 RQFHQFGVETFGVATPDIDAELILMTARLWKRMGVSEKVQLELNTLGEIDERAAYRTALV 183
RQFHQ GVE+FG A PD DAELI MT +W+ +G+ ++++LELN+LGEIDER AYR ALV
Sbjct 122 RQFHQIGVESFGSALPDADAELIAMTHLMWQELGLKDEMRLELNSLGEIDERHAYREALV 181
Query 184 EFLTQHKEALDEDSQRRLGTNPLRILDSKVESTQKILENAPKLHDFLQEDSLAHFNQLQE 243
+LT +E LDEDS+RRL TNPLRILDSK STQ +L +APKL DFL E+S+AHF Q+Q
Sbjct 182 TYLTDKQEQLDEDSKRRLTTNPLRILDSKEASTQALLVDAPKLADFLGEESVAHFEQVQA 241
Query 244 YLTHAGVSFVINQKLVRGLDYYNKTVFEWTTTALGSQGTVCAGGRYDGLVGQLK------ 297
YLT G++F IN LVRGLDYYNKTVFEW T LGSQ TVCAGGRYDGLVGQLK
Sbjct 242 YLTELGINFEINPHLVRGLDYYNKTVFEWVTDKLGSQATVCAGGRYDGLVGQLKSADNRD 301
Query 298 GKAD----QSVPAVGFAMGMERLLLLLEQVEQAEVVRDCDVFLVAESAFQGHALVLAEQI 353
GK D +S PAVGFAMG+ERLLLL+E V + CDVF+VA + A+ +
Sbjct 302 GKGDNKPVKSEPAVGFAMGLERLLLLMEVVAPIADMPACDVFVVAHPEVYSAGISYAQNL 361
Query 354 RDQFEGLASTIRVKTGSQGSMKSQMKKADQSGAHYAVILGEREWTTQELTVKELATSEQS 413
R +RVK S S+K+QMKKAD+SGA VI+ ++E + +++K++ T EQ
Sbjct 362 RYS----RPDLRVKMASATSLKAQMKKADKSGAALTVIIAQQELDDKTISIKDMQTGEQK 417
Query 414 QVA 416
A
Sbjct 418 TAA 420
>A5WGQ0 Histidine--tRNA ligase [Psychrobacter sp. (strain PRwf-1)]
Length=436
Score = 487 bits (1253), Expect = 2e-174
Identities = 250/423 (59%), Positives = 307/423 (73%), Gaps = 18/423 (4%)
Query 4 IVAIKGFNDVLPTQTAA------WRRLEQHLASLMDAYGYQQIRLPIVEQTGLFKRAIGD 57
I +IKGFND+L +TA WR+LE L +D +GY++IRLPIVE+T LF RAIGD
Sbjct 2 IKSIKGFNDILQVETATSRPSSEWRQLEAMLKQALDQFGYEEIRLPIVEETQLFARAIGD 61
Query 58 ATDIVEKEMYTFFDKGTPPESLTLRPEGTAGCVRAMLEHNLLRGATPRVWYVGPMFRYEK 117
ATDIVEKEM++F DK PP +TLRPEGTAG VRA++EHNLLRG +P++WY+GPMFRYE+
Sbjct 62 ATDIVEKEMFSFTDKSDPPTPITLRPEGTAGAVRAVIEHNLLRGDSPKLWYMGPMFRYEQ 121
Query 118 PQKGRYRQFHQFGVETFGVATPDIDAELILMTARLWKRMGVSEKVQLELNTLGEIDERAA 177
PQKGRYRQFHQ GVE FG D++AELI MT +W+R+G+ ++ LE+N+LGE+DER A
Sbjct 122 PQKGRYRQFHQLGVEAFGSEHVDVEAELIAMTYLMWQRLGIDHELSLEINSLGELDERKA 181
Query 178 YRTALVEFLTQHKEALDEDSQRRLGTNPLRILDSKVESTQKILENAPKLHDFLQEDSLAH 237
YR+ALVEFL KE LDEDSQRRL TNPLRILDSK +TQ +L AP+L DFL EDS AH
Sbjct 182 YRSALVEFLQTKKEQLDEDSQRRLTTNPLRILDSKDPNTQALLMEAPRLADFLGEDSQAH 241
Query 238 FNQLQEYLTHAGVSFVINQKLVRGLDYYNKTVFEWTTTALGSQGTVCAGGRYDGLVGQL- 296
F QL+ YLT G+ +V+N LVRGLDYYNKTVFEW T LGSQ TVCAGGRYDGL+GQL
Sbjct 242 FEQLKTYLTALGIEYVVNPNLVRGLDYYNKTVFEWVTDKLGSQATVCAGGRYDGLIGQLK 301
Query 297 -------KGKADQSVPAVGFAMGMERLLLLLEQVEQAEVVRDCDVFLVAESAFQGHALVL 349
K KA +S PAVGFAMG+ERLLLL++ V + CDVF+V L+
Sbjct 302 SIGKSEDKAKAVKSEPAVGFAMGLERLLLLVQAVNPIQAQPACDVFVVVHPDLYQQGLLY 361
Query 350 AEQIRDQFEGLASTIRVKTGSQGSMKSQMKKADQSGAHYAVILGEREWTTQELTVKELAT 409
A+ +R S +RVK S S+K+QMKKAD+SGA VIL + E + ++VK + T
Sbjct 362 AQSLRQ----ARSDLRVKMASASSLKAQMKKADKSGAQLTVILAQDEVESGTISVKTMHT 417
Query 410 SEQ 412
EQ
Sbjct 418 GEQ 420
>Q4FTW6 Histidine--tRNA ligase [Psychrobacter arcticus (strain
DSM 17307 / VKM B-2377 / 273-4)]
Length=442
Score = 487 bits (1253), Expect = 2e-174
Identities = 255/431 (59%), Positives = 309/431 (72%), Gaps = 22/431 (5%)
Query 4 IVAIKGFNDVLPTQTAAWRRLEQHLASLMDAYGYQQIRLPIVEQTGLFKRAIGDATDIVE 63
I AIKGFND+LP Q+A W LE LA ++ YGY+ IRLPIVEQT LF RAIG ATDIVE
Sbjct 2 IKAIKGFNDILPAQSAKWLYLESILADVLGRYGYEHIRLPIVEQTDLFARAIGGATDIVE 61
Query 64 KEMYTFFDKGTPPESLTLRPEGTAGCVRAMLEHNLLRGATPRVWYVGPMFRYEKPQKGRY 123
KEMY+F DK PP LTLRPEGTAG VRA+ EHNLLRG TP++WY+GPMFRYE+PQKGRY
Sbjct 62 KEMYSFTDKSDPPTPLTLRPEGTAGAVRAVNEHNLLRGDTPKLWYIGPMFRYERPQKGRY 121
Query 124 RQFHQFGVETFGVATPDIDAELILMTARLWKRMGVSEKVQLELNTLGEIDERAAYRTALV 183
RQFHQ GVE+FG A PD DAELI MT +W+ +G+ ++++L+LN+LGE DER AYR ALV
Sbjct 122 RQFHQLGVESFGSALPDADAELIAMTHLMWQELGLKDEMRLQLNSLGERDERHAYREALV 181
Query 184 EFLTQHKEALDEDSQRRLGTNPLRILDSKVESTQKILENAPKLHDFLQEDSLAHFNQLQE 243
+LT +E LDEDS+RRL TNPLRILDSK STQ +L +APKL +FL E+S+AHF Q+Q
Sbjct 182 TYLTDKQEQLDEDSKRRLTTNPLRILDSKEASTQALLIDAPKLANFLGEESVAHFEQVQT 241
Query 244 YLTHAGVSFVINQKLVRGLDYYNKTVFEWTTTALGSQGTVCAGGRYDGLVGQLK------ 297
YLT G+ F IN LVRGLDYYNKTVFEW T LGSQ TVCAGGRYDGLVGQLK
Sbjct 242 YLTELGIDFEINPHLVRGLDYYNKTVFEWVTDKLGSQATVCAGGRYDGLVGQLKSIDTRD 301
Query 298 GKAD------------QSVPAVGFAMGMERLLLLLEQVEQAEVVRDCDVFLVAESAFQGH 345
KAD +S PAVGFAMG+ERLLLL++ V + CDVF+VA
Sbjct 302 AKADAKADAKADSKPVKSEPAVGFAMGLERLLLLIDAVAPIADIPACDVFVVAHPEVYSA 361
Query 346 ALVLAEQIRDQFEGLASTIRVKTGSQGSMKSQMKKADQSGAHYAVILGEREWTTQELTVK 405
+ A+ +R +RVK S S+K+QMKKAD+SGA VI+ ++E + +++K
Sbjct 362 GIGYAQNLRYS----RPDLRVKMASATSLKAQMKKADKSGAALTVIIAQQEIDDKTISIK 417
Query 406 ELATSEQSQVA 416
++ T EQ A
Sbjct 418 DMQTGEQKTAA 428
>A8GHW4 Histidine--tRNA ligase [Serratia proteamaculans (strain
568)]
Length=424
Score = 464 bits (1194), Expect = 9e-166
Identities = 240/421 (57%), Positives = 309/421 (73%), Gaps = 12/421 (3%)
Query 3 SIVAIKGFNDVLPTQTAAWRRLEQHLASLMDAYGYQQIRLPIVEQTGLFKRAIGDATDIV 62
+I AI+G ND LP +TA W+R+E L ++ YGY +IRLPIVEQT LFKRAIG+ TD+V
Sbjct 4 NIQAIRGMNDYLPEETALWQRIEGILKQVLSGYGYSEIRLPIVEQTPLFKRAIGEVTDVV 63
Query 63 EKEMYTFFDKGTPPESLTLRPEGTAGCVRAMLEHNLLRGATPRVWYVGPMFRYEKPQKGR 122
EKEMYTF D+ ESLTLRPEGTAGCVRA +EH LL R+WYVGPMFRYE+PQKGR
Sbjct 64 EKEMYTFDDRNG--ESLTLRPEGTAGCVRAGIEHGLLYNQEQRLWYVGPMFRYERPQKGR 121
Query 123 YRQFHQFGVETFGVATPDIDAELILMTARLWKRMGVSEKVQLELNTLGEIDERAAYRTAL 182
YRQFHQ G E FG+ PDIDAELIL++AR WK +G+SE V+LELN++G ++ RA YR AL
Sbjct 122 YRQFHQLGAEVFGLQGPDIDAELILLSARWWKALGISEHVKLELNSIGSLEARANYRDAL 181
Query 183 VEFLTQHKEALDEDSQRRLGTNPLRILDSKVESTQKILENAPKLHDFLQEDSLAHFNQLQ 242
V FL QH+E LDED +RR+ +NPLR+LDSK Q +L +AP+L ++L DS AHF L
Sbjct 182 VAFLEQHQEKLDEDCKRRMYSNPLRVLDSKNPEVQALLNDAPRLSEYLDADSKAHFEGLC 241
Query 243 EYLTHAGVSFVINQKLVRGLDYYNKTVFEWTTTALGSQGTVCAGGRYDGLVGQLKGKADQ 302
E L AG+ + IN++LVRGLDYYN+TVFEW TT+LG+QGTVCAGGRYDGLV QL G+A
Sbjct 242 ELLAQAGIPYTINERLVRGLDYYNRTVFEWVTTSLGAQGTVCAGGRYDGLVEQLGGRA-- 299
Query 303 SVPAVGFAMGMERLLLLLEQVE-QAEVVRDCDVFLVAESA-FQGHALVLAEQIRDQFEGL 360
PAVGFAMG+ERL+LL++ V + + DV++++ A Q A+ LAE++RD
Sbjct 300 -TPAVGFAMGLERLVLLVQAVNPEFKAAATIDVYVISSGAGTQSAAMQLAERVRD----A 354
Query 361 ASTIRVKTG-SQGSMKSQMKKADQSGAHYAVILGEREWTTQELTVKELATSEQSQVAISE 419
A +++ T G+ K Q+ +AD+ GA A+ILGE E Q++ VK+L + EQ +A SE
Sbjct 355 APQLKLMTNYGGGNFKKQITRADKWGARVALILGENEVAAQQVVVKDLRSGEQETLAQSE 414
Query 420 L 420
+
Sbjct 415 V 415
>P60906 Histidine--tRNA ligase [Escherichia coli (strain K12)]
Length=424
Score = 457 bits (1175), Expect = 7e-163
Identities = 239/419 (57%), Positives = 306/419 (73%), Gaps = 16/419 (4%)
Query 3 SIVAIKGFNDVLPTQTAAWRRLEQHLASLMDAYGYQQIRLPIVEQTGLFKRAIGDATDIV 62
+I AI+G ND LP +TA W+R+E L +++ +YGY +IRLPIVEQT LFKRAIG+ TD+V
Sbjct 4 NIQAIRGMNDYLPGETAIWQRIEGTLKNVLGSYGYSEIRLPIVEQTPLFKRAIGEVTDVV 63
Query 63 EKEMYTFFDKGTPPESLTLRPEGTAGCVRAMLEHNLLRGATPRVWYVGPMFRYEKPQKGR 122
EKEMYTF D+ +SLTLRPEGTAGCVRA +EH LL R+WY+GPMFR+E+PQKGR
Sbjct 64 EKEMYTFEDRNG--DSLTLRPEGTAGCVRAGIEHGLLYNQEQRLWYIGPMFRHERPQKGR 121
Query 123 YRQFHQFGVETFGVATPDIDAELILMTARLWKRMGVSEKVQLELNTLGEIDERAAYRTAL 182
YRQFHQ G E FG+ PDIDAELI++TAR W+ +G+SE V LELN++G ++ RA YR AL
Sbjct 122 YRQFHQLGCEVFGLQGPDIDAELIMLTARWWRALGISEHVTLELNSIGSLEARANYRDAL 181
Query 183 VEFLTQHKEALDEDSQRRLGTNPLRILDSKVESTQKILENAPKLHDFLQEDSLAHFNQLQ 242
V FL QHKE LDED +RR+ TNPLR+LDSK Q +L +AP L D+L E+S HF L
Sbjct 182 VAFLEQHKEKLDEDCKRRMYTNPLRVLDSKNPEVQALLNDAPALGDYLDEESREHFAGLC 241
Query 243 EYLTHAGVSFVINQKLVRGLDYYNKTVFEWTTTALGSQGTVCAGGRYDGLVGQLKGKADQ 302
+ L AG+++ +NQ+LVRGLDYYN+TVFEW T +LGSQGTVCAGGRYDGLV QL G+A
Sbjct 242 KLLESAGIAYTVNQRLVRGLDYYNRTVFEWVTNSLGSQGTVCAGGRYDGLVEQLGGRA-- 299
Query 303 SVPAVGFAMGMERLLLLLEQVE---QAEVVRDCDVFLVAESA-FQGHALVLAEQIRDQFE 358
PAVGFAMG+ERL+LL++ V +A+ V D++LVA A Q A+ LAE++RD+
Sbjct 300 -TPAVGFAMGLERLVLLVQAVNPEFKADPV--VDIYLVASGADTQSAAMALAERLRDELP 356
Query 359 GLASTIRVKTG-SQGSMKSQMKKADQSGAHYAVILGEREWTTQELTVKELATSEQSQVA 416
G +++ T G+ K Q +AD+ GA AV+LGE E VK+L + EQ+ VA
Sbjct 357 G----VKLMTNHGGGNFKKQFARADKWGARVAVVLGESEVANGTAVVKDLRSGEQTAVA 411
>O52765 Histidine--tRNA ligase [Salmonella typhimurium (strain
LT2 / SGSC1412 / ATCC 700720)]
Length=424
Score = 455 bits (1170), Expect = 4e-162
Identities = 234/417 (56%), Positives = 304/417 (73%), Gaps = 12/417 (3%)
Query 3 SIVAIKGFNDVLPTQTAAWRRLEQHLASLMDAYGYQQIRLPIVEQTGLFKRAIGDATDIV 62
+I AI+G ND LP +TA W+R+E L +++ +YGY +IRLPIVEQT LFKRAIG+ TD+V
Sbjct 4 NIQAIRGMNDYLPGETAIWQRIEGTLKNVLGSYGYSEIRLPIVEQTPLFKRAIGEVTDVV 63
Query 63 EKEMYTFFDKGTPPESLTLRPEGTAGCVRAMLEHNLLRGATPRVWYVGPMFRYEKPQKGR 122
EKEMYTF D+ +SLTLRPEGTAGCVRA +EH LL R+WY+GPMFR+E+PQKGR
Sbjct 64 EKEMYTFEDRNG--DSLTLRPEGTAGCVRAGIEHGLLYNQEQRLWYIGPMFRHERPQKGR 121
Query 123 YRQFHQFGVETFGVATPDIDAELILMTARLWKRMGVSEKVQLELNTLGEIDERAAYRTAL 182
YRQFHQ G E FG+ PDIDAELI++TAR W+ +G++E V LELN++G ++ RA YR AL
Sbjct 122 YRQFHQLGAEVFGLQGPDIDAELIMLTARWWRALGIAEHVSLELNSIGSLEARANYRDAL 181
Query 183 VEFLTQHKEALDEDSQRRLGTNPLRILDSKVESTQKILENAPKLHDFLQEDSLAHFNQLQ 242
V FL QH+E LDED +RR+ TNPLR+LDSK Q +L +AP L D+L +DS HF L
Sbjct 182 VAFLEQHQETLDEDCKRRMYTNPLRVLDSKNPDVQALLNDAPALGDYLDDDSREHFAGLC 241
Query 243 EYLTHAGVSFVINQKLVRGLDYYNKTVFEWTTTALGSQGTVCAGGRYDGLVGQLKGKADQ 302
+ L AG+++ +NQ+LVRGLDYYN+TVFEW T +LGSQGTVCAGGRYDGLV QL G+A
Sbjct 242 KLLDAAGIAYTVNQRLVRGLDYYNRTVFEWVTNSLGSQGTVCAGGRYDGLVEQLGGRA-- 299
Query 303 SVPAVGFAMGMERLLLLLEQVEQAEVVRD-CDVFLVAESA-FQGHALVLAEQIRDQFEGL 360
PAVGFAMG+ERL+LL++ V + D++LVA A Q A+ LAE++RD+ G
Sbjct 300 -TPAVGFAMGLERLVLLVQAVNPEFIASPVVDIYLVAAGAQTQSAAMTLAERLRDEMPG- 357
Query 361 ASTIRVKTG-SQGSMKSQMKKADQSGAHYAVILGEREWTTQELTVKELATSEQSQVA 416
+++ T G+ K Q +AD+ GA A++LGE E + VK+L + EQ+ VA
Sbjct 358 ---VKLMTNHGGGNFKKQFARADKWGARIALVLGESEVADGTVVVKDLRSGEQTAVA 411
>P60911 Histidine--tRNA ligase [Staphylococcus aureus]
Length=420
Score = 304 bits (778), Expect = 6e-103
Identities = 167/426 (39%), Positives = 253/426 (59%), Gaps = 18/426 (4%)
Query 8 KGFNDVLPTQTAAWRRLEQHLASLMDAYGYQQIRLPIVEQTGLFKRAIGDATDIVEKEMY 67
+G D+LP + WR +E L LM Y Y++IR PI E T LF R +GD+TD+V+KEMY
Sbjct 6 RGTQDILPEDSKKWRYIENQLDELMTFYNYKEIRTPIFESTDLFARGVGDSTDVVQKEMY 65
Query 68 TFFDKGTPPESLTLRPEGTAGCVRAMLEHNLLRGATP--RVWYVGPMFRYEKPQKGRYRQ 125
TF DKG S+TLRPEGTA VR+ +EH + +++Y GPMFRYE+ QKGRYRQ
Sbjct 66 TFKDKGD--RSITLRPEGTAAVVRSYIEHKMQGNPNQPIKLYYNGPMFRYERKQKGRYRQ 123
Query 126 FHQFGVETFGVATPDIDAELILMTARLWKRMGVSEKVQLELNTLGEIDERAAYRTALVEF 185
F+QFGVE G P +DAE++ M +++ G+ ++L +N++G++ R Y ALV+
Sbjct 124 FNQFGVEAIGAENPSVDAEVLAMVMHIYQSFGLKH-LKLVINSVGDMASRKEYNEALVKH 182
Query 186 LTQHKEALDEDSQRRLGTNPLRILDSKVESTQKILENAPKLHDFLQEDSLAHFNQLQEYL 245
D Q RL TNP+RILD KV+ ++ ++ AP++ DFL E+S A++ Q++ YL
Sbjct 183 FEPVIHEFCSDCQSRLHTNPMRILDCKVDRDKEAIKTAPRITDFLNEESKAYYEQVKAYL 242
Query 246 THAGVSFVINQKLVRGLDYYNKTVFEWTTTALGSQG---TVCAGGRYDGLVGQLKGKADQ 302
G+ ++ + LVRGLDYY T FE G T+C GGRY+GL+ L G ++
Sbjct 243 DDLGIPYIEDPNLVRGLDYYTHTAFELMMDNPNYDGAITTLCGGGRYNGLLELLDGPSE- 301
Query 303 SVPAVGFAMGMERLLLLLEQVE-QAEVVRDCDVFLVA-ESAFQGHALVLAEQIRDQFEGL 360
+GFA+ +ERLLL LE+ + ++ + D+F+V +A+ L +R G+
Sbjct 302 --TGIGFALSIERLLLALEEEGIELDIEENLDLFIVTMGDQADRYAVKLLNHLR--HNGI 357
Query 361 ASTIRVKTGSQGSMKSQMKKADQSGAHYAVILGEREWTTQELTVKELATSEQSQVAISEL 420
+ K Q +K QMK+AD+ GA + +++G++E ++ VK + T E + + L
Sbjct 358 KAD---KDYLQRKIKGQMKQADRLGAKFTIVIGDQELENNKIDVKNMTTGESETIELDAL 414
Query 421 VPFLVK 426
V + K
Sbjct 415 VEYFKK 420
>P30053 Histidine--tRNA ligase [Streptococcus dysgalactiae subsp.
equisimilis]
Length=426
Score = 293 bits (749), Expect = 2e-98
Identities = 172/419 (41%), Positives = 241/419 (58%), Gaps = 18/419 (4%)
Query 8 KGFNDVLPTQTAAWRRLEQHLASLMDAYGYQQIRLPIVEQTGLFKRAIGDATDIVEKEMY 67
KG D+L A W+ +E Y Y +IR P+ E + R++GD TDIV KEMY
Sbjct 7 KGTQDILSVAAAKWQYVEGVARETFKQYHYGEIRTPMFEHYEVISRSVGDTTDIVTKEMY 66
Query 68 TFFDKGTPPESLTLRPEGTAGCVRAMLEHNLLRGATPR---VWYVGPMFRYEKPQKGRYR 124
F+DKG +TLRPEGTA VR+ +E+ L + ++Y+G MFRYE+PQ GR R
Sbjct 67 DFYDKGD--RHITLRPEGTAPVVRSYVENKLFAPEVQKPVKLYYIGSMFRYERPQAGRLR 124
Query 125 QFHQFGVETFGVATPDIDAELILMTARLWKRMGVSEKVQLELNTLGEIDERAAYRTALVE 184
+FHQ GVE FG A P D E I M L++R+G+ + V L LN+LG RAAYR AL++
Sbjct 125 EFHQIGVECFGSANPATDVETIAMAYHLFERLGI-KGVTLHLNSLGNAASRAAYRQALID 183
Query 185 FLTQHKEALDEDSQRRLGTNPLRILDSKVESTQKILENAPKLHDFLQEDSLAHFNQLQEY 244
+L+ ++ L +DSQRRL NPLR+LDSK + + + NAP + D+ E+S AHF+ ++
Sbjct 184 YLSPMRDTLSKDSQRRLDENPLRVLDSKEKEDKIAVANAPSILDYQDEESQAHFDAVRSM 243
Query 245 LTHAGVSFVINQKLVRGLDYYNKTVFEWTTTALGSQGTVCAGGRYDGLVGQLKGKADQSV 304
L + +VI+ +VRGLDYYN T+FE+ T S+ T+CAGGRYDGLV G A
Sbjct 244 LEALAIPYVIDTNMVRGLDYYNHTIFEFITEVDQSELTICAGGRYDGLVEYFGGPA---T 300
Query 305 PAVGFAMGMERLLLLLE-QVEQAEVVRDCDVFLVAESAFQG-HALVLAEQIRDQFEGLAS 362
P GF +G+ERLLL+L+ Q + V DV++ A AL L + IR Q
Sbjct 301 PGFGFGLGLERLLLILDKQGVELPVEEGLDVYIAVLGADANVAALALTQAIRRQ------ 354
Query 363 TIRVKTGSQG-SMKSQMKKADQSGAHYAVILGEREWTTQELTVKELATSEQSQVAISEL 420
V+ G +K+Q K AD A + LGE E + +K T ++ V+ ++
Sbjct 355 GFTVERDYLGRKIKAQFKSADTFKAKVVITLGESEIKAGQAVLKHNQTRQEMTVSFDQI 413
>P56194 Histidine--tRNA ligase [Thermus thermophilus (strain ATCC
27634 / DSM 579 / HB8)]
Length=421
Score = 268 bits (684), Expect = 7e-89
Identities = 166/427 (39%), Positives = 247/427 (58%), Gaps = 19/427 (4%)
Query 6 AIKGFNDVLPTQTAAWRRLEQHLASLMDAYGYQQIRLPIVEQTGLFKRAIGDATDIVEKE 65
A++G D+ + +R+ +++A G ++ PI E+T +F++ +G ATDIV KE
Sbjct 5 AVRGTKDLFGKELRMHQRIVATARKVLEAAGALELVTPIFEETQVFEKGVGAATDIVRKE 64
Query 66 MYTFFDKGTPPESLTLRPEGTAGCVRAMLEHNLLRGATP-RVWYVGPMFRYEKPQKGRYR 124
M+TF D+G SLTLRPEGTA VRA LEH + P R+W GPMFR E+PQKGRYR
Sbjct 65 MFTFQDRGG--RSLTLRPEGTAAMVRAYLEHGMKVWPQPVRLWMAGPMFRAERPQKGRYR 122
Query 125 QFHQFGVETFGVATPDIDAELILMTARLWKRMGVSEKVQLELNTLGEIDERAAYRTALVE 184
QFHQ E G P +DAE +++ K +G+ +++++L+++G+ ++RA Y L E
Sbjct 123 QFHQVNYEALGSENPILDAEAVVLLYECLKELGL-RRLKVKLSSVGDPEDRARYNAYLRE 181
Query 185 FLTQHKEALDEDSQRRLGTNPLRILDSKVESTQKILE--NAPKLHDFLQEDSLAHFNQLQ 242
L+ H+EAL EDS+ RL NP+RILDSK E Q +L+ + DFL E++ AH +++
Sbjct 182 VLSPHREALSEDSKERLELNPMRILDSKSERDQALLKELGVRPMLDFLGEEARAHLKEVE 241
Query 243 EYLTHAGVSFVINQKLVRGLDYYNKTVFEWTTTALGSQGTVCAGGRYDGLVGQLKGKADQ 302
+L V + + LVRGLDYY +T FE +G+Q + GGRYDGL L G
Sbjct 242 RHLERLSVPYELEPALVRGLDYYVRTAFEVHHEEIGAQSALGGGGRYDGLSELLGG---P 298
Query 303 SVPAVGFAMGMERLLLLLEQVE---QAEVVRDCDVFLVAESAFQGHALVLAEQIRDQFEG 359
VP VGFA G+ER+ L LE E D + + E A A LAE +R +
Sbjct 299 RVPGVGFAFGVERVALALEAEGFGLPEEKGPDLYLIPLTEEAV-AEAFYLAEALRPRLRA 357
Query 360 LASTIRVKTGSQGSMKSQMKKADQSGAHYAVILGEREWTTQELTVKELATSEQSQVAISE 419
+ + ++G +++A + GA +A LGE E E+T+K LAT EQ +++ E
Sbjct 358 -EYALAPRKPAKG-----LEEALKRGAAFAGFLGEDELRAGEVTLKRLATGEQVRLSREE 411
Query 420 LVPFLVK 426
+ +L++
Sbjct 412 VPGYLLQ 418
>O82413 Histidine--tRNA ligase, chloroplastic/mitochondrial [Arabidopsis
thaliana]
Length=486
Score = 124 bits (311), Expect = 3e-34
Identities = 114/432 (26%), Positives = 198/432 (46%), Gaps = 38/432 (9%)
Query 8 KGFNDVLPTQTAAWRRLEQHLASLMDAYGYQQIRLPIVEQTGLFKRAIGDATDIVEKEMY 67
KG D P L H + YGY+++ P++E LF R G+ + ++Y
Sbjct 73 KGTRDFPPEDMRLRNWLFNHFKEVSRLYGYEEVDYPVLETEALFIRKAGEE---IRDQLY 129
Query 68 TFFDKGTPPESLTLRPEGTAGCVRAMLEHNLLRGATPRVWY-VGPMFRYEKPQKGRYRQF 126
F D+G + LRPE T R +++ + P W+ +G +RYE+ +GR R+
Sbjct 130 CFEDRGN--RRVALRPELTPSLARLVIQKGK-SVSLPLKWFAIGQCWRYERMTRGRRREH 186
Query 127 HQFGVETFGVATPDIDAELILMTARLWKRMGV----------SEKVQLELNTLGEIDERA 176
+Q+ ++ GV +AELI +KR+G+ S KV EL + E
Sbjct 187 YQWNMDIIGVPQVTAEAELISSIVTFFKRIGITASDVGFKVSSRKVLQELLKKYGVPEDL 246
Query 177 AYRTALVEFLTQHKEALDEDSQRRLGTNPLRILDSKVESTQKIL--ENAPKLHDFL--QE 232
R ++ + + ++ ++ ++ LG I + +E ++L ++ L D +
Sbjct 247 FGRVCII--IDKIEKIPIDEIKKELGFT--GISEDAIEQLLQVLSVKSLDDLEDIIGGAG 302
Query 233 DSLAHFNQLQEYLTHAGVS--FVINQKLVRGLDYYNKTVFEWTTTALGSQGTVCAGGRYD 290
+++A QL G S + +VRGL YY VFE G +C GGRYD
Sbjct 303 EAIADLKQLFSLAEKFGYSEWIQFDASVVRGLAYYTGIVFEGFDRK-GKLRAICGGGRYD 361
Query 291 GLVGQLKGKADQSVPAVGFAMGMERLLLLLEQVE-QAEVVRDCDVFLVA-ESAFQGHALV 348
L+ G PA GF G ++ LL++ + E+ ++ + + A + QG A
Sbjct 362 RLLSTYGG---DDFPACGFGFGDAVIVELLKEKDLLPELGQEVENIVCALDKDLQGAAAT 418
Query 349 LAEQIRDQFEGLASTIRVKTGSQGSMKSQMKKADQSGAHYAVILGEREWTTQELTVKELA 408
+A +RD+ + + + K +K K+A + A V++G+ EW ++VK L+
Sbjct 419 VATALRDKGQTVDLVLESK-----PLKWVFKRAARVNARRLVLVGKTEWEDGSVSVKVLS 473
Query 409 TSEQSQVAISEL 420
+ EQ QV +S+L
Sbjct 474 SGEQFQVKLSDL 485
>Q61035 Histidine--tRNA ligase, cytoplasmic [Mus musculus]
Length=509
Score = 93.2 bits (230), Expect = 2e-23
Identities = 112/452 (25%), Positives = 199/452 (44%), Gaps = 54/452 (12%)
Query 8 KGFNDVLPTQTAAWRRLEQHLASLMDAYGYQQIRLPIVEQTGLFKRAIGDATDIVEKEMY 67
KG D P Q A ++ + +G + I P+ E G+ + ++ Y
Sbjct 60 KGTRDYSPRQMAVREKVFDVIIRCFKRHGAEVIDTPVFELKETLTGKYGEDSKLI----Y 115
Query 68 TFFDKGTPPESLTLRPEGTAGCVRAMLEHNLLRGATPRVWYVGPMFRYEKPQ--KGRYRQ 125
D+G E L+LR + T R + + L + +++ ++R + P +GRYR+
Sbjct 116 DLKDQGG--ELLSLRYDLTVPFARYLAMNKL---TNIKRYHIAKVYRRDNPAMTRGRYRE 170
Query 126 FHQFGVETFGVATPDI-DAELILMTARLWKRMGVSEKVQLELNTLGEIDERAA------- 177
F+Q + G P I DAE + + + + + + +++N +D A
Sbjct 171 FYQCDFDIAGQFDPMIPDAECLKIMCEILSSLQIGNFL-VKVNDRRILDGMFAVCGVPDS 229
Query 178 -YRTALVEFLTQHKEALDEDSQRRLGTNPL------RILD-----SKVESTQKILENAPK 225
+RT K + +E +G L RI D V +++L++ PK
Sbjct 230 KFRTICSSVDKLDKVSWEEVKNEMVGEKGLAPEVADRIGDYVQQHGGVSLVEQLLQD-PK 288
Query 226 LHDFLQE-DSLAHFNQLQEYLTHAGVSFVIN--QKLVRGLDYYNKTVFEWTTTALGSQ-- 280
L Q + L L EYL G+ I+ L RGLDYY ++E + +Q
Sbjct 289 LSQNKQAVEGLGDLKLLFEYLILFGIDDKISFDLSLARGLDYYTGVIYEAVLLQMPTQAG 348
Query 281 ------GTVCAGGRYDGLVGQLKGKADQSVPAVGFAMGMERLLLLLEQVEQA--EVVRDC 332
G++ AGGRYDGLVG K + VP VG ++G+ER+ ++EQ +A E VR
Sbjct 349 EEPLGVGSIAAGGRYDGLVGMFDPKG-RKVPCVGLSIGVERIFSIVEQRLEASEEKVRTT 407
Query 333 DVFLVAESA---FQGHALVLAEQIRDQFEGLASTIRVKTGSQGSMKSQMKKADQSGAHYA 389
+ ++ SA L L ++ D G+ + + K + + +Q++ +++G
Sbjct 408 ETQVLVASAQKKLLEERLKLVSELWD--AGIKAELLYKKNPK--LLNQLQYCEEAGIPLV 463
Query 390 VILGEREWTTQELTVKELATSEQSQVAISELV 421
I+GE+E + ++ +A+ E+ V +LV
Sbjct 464 AIIGEQELKDGVIKLRSVASREEVDVRREDLV 495
>P12081 Histidine--tRNA ligase, cytoplasmic [Homo sapiens]
Length=509
Score = 93.2 bits (230), Expect = 2e-23
Identities = 112/452 (25%), Positives = 199/452 (44%), Gaps = 54/452 (12%)
Query 8 KGFNDVLPTQTAAWRRLEQHLASLMDAYGYQQIRLPIVEQTGLFKRAIGDATDIVEKEMY 67
KG D P Q A ++ + +G + I P+ E G+ + ++ Y
Sbjct 60 KGTRDYSPRQMAVREKVFDVIIRCFKRHGAEVIDTPVFELKETLMGKYGEDSKLI----Y 115
Query 68 TFFDKGTPPESLTLRPEGTAGCVRAMLEHNLLRGATPRVWYVGPMFRYEKPQ--KGRYRQ 125
D+G E L+LR + T R + + L + +++ ++R + P +GRYR+
Sbjct 116 DLKDQGG--ELLSLRYDLTVPFARYLAMNKL---TNIKRYHIAKVYRRDNPAMTRGRYRE 170
Query 126 FHQFGVETFGVATPDI-DAELILMTARLWKRMGVSEKVQLELNTLGEIDERAA------- 177
F+Q + G P I DAE + + + + + + + +++N +D A
Sbjct 171 FYQCDFDIAGNFDPMIPDAECLKIMCEILSSLQIGDFL-VKVNDRRILDGMFAICGVSDS 229
Query 178 -YRTALVEFLTQHKEALDEDSQRRLGTNPL------RILD-----SKVESTQKILENAPK 225
+RT K + +E +G L RI D V +++L++ PK
Sbjct 230 KFRTICSSVDKLDKVSWEEVKNEMVGEKGLAPEVADRIGDYVQQHGGVSLVEQLLQD-PK 288
Query 226 LHDFLQE-DSLAHFNQLQEYLTHAGVSFVIN--QKLVRGLDYYNKTVFEWTTTALGSQ-- 280
L Q + L L EYLT G+ I+ L RGLDYY ++E +Q
Sbjct 289 LSQNKQALEGLGDLKLLFEYLTLFGIDDKISFDLSLARGLDYYTGVIYEAVLLQTPAQAG 348
Query 281 ------GTVCAGGRYDGLVGQLKGKADQSVPAVGFAMGMERLLLLLEQVEQA--EVVRDC 332
G+V AGGRYDGLVG K + VP VG ++G+ER+ ++EQ +A E +R
Sbjct 349 EEPLGVGSVAAGGRYDGLVGMFDPKG-RKVPCVGLSIGVERIFSIVEQRLEALEEKIRTT 407
Query 333 DVFLVAESA---FQGHALVLAEQIRDQFEGLASTIRVKTGSQGSMKSQMKKADQSGAHYA 389
+ ++ SA L L ++ D G+ + + K + + +Q++ +++G
Sbjct 408 ETQVLVASAQKKLLEERLKLVSELWD--AGIKAELLYKKNPK--LLNQLQYCEEAGIPLV 463
Query 390 VILGEREWTTQELTVKELATSEQSQVAISELV 421
I+GE+E + ++ + + E+ V +LV
Sbjct 464 AIIGEQELKDGVIKLRSVTSREEVDVRREDLV 495
>P70076 Histidine--tRNA ligase, cytoplasmic [Takifugu rubripes]
Length=519
Score = 90.5 bits (223), Expect = 1e-22
Identities = 107/468 (23%), Positives = 209/468 (45%), Gaps = 64/468 (14%)
Query 8 KGFNDVLPTQTAAWRRLEQHLASLMDAYGYQQIRLPIVEQTGLFKRAIGDATDIVEKEMY 67
KG D P Q A ++ + S +G + I P+ E G+ + ++ Y
Sbjct 65 KGTRDYNPKQMAIREKVFNTIVSCFKRHGAETIDTPVFELKETLTGKYGEDSKLI----Y 120
Query 68 TFFDKGTPPESLTLRPEGTAGCVRAMLEHNLLRGATPRVWYVGPMFRYEKPQ--KGRYRQ 125
D+G E L+LR + T R + + + + +++ ++R + P +GRYR+
Sbjct 121 DLKDQGG--ELLSLRYDLTVPFARYLAMNKI---TNIKRYHIAKVYRRDNPAMTRGRYRE 175
Query 126 FHQFGVETFGVATPDI-DAELILMTARLWKRMGVSEKVQLELNTLGEIDERAA------- 177
F+Q + G I DAE + + + + + + ++++N +D A
Sbjct 176 FYQCDFDIAGQYDAMIPDAECLKIVHEILSELDLGD-FRIKVNDRRILDGMFAVCGVPDN 234
Query 178 -YRT--ALVEFLTQ-----------HKEALDEDSQRRLGTNPLRILDSKVESTQKILENA 223
+RT + V+ L + +++ L E++ ++G + ++ +++L++
Sbjct 235 MFRTICSTVDKLDKLPWEAVKNEMVNEKGLSEEAADQIGVYVG--MQGGMDLAERLLQDQ 292
Query 224 PKLHDFLQEDSLAHFNQLQEYLTHAGVS--FVINQKLVRGLDYYNKTVFEWTTTALG--- 278
L L YL V+ V + L RGLDYY ++E T G
Sbjct 293 KMCQSTQACAGLTDIKLLFSYLQLFQVTDKVVFDLSLARGLDYYTGIIYEAILTQAGVAP 352
Query 279 ---------------SQGTVCAGGRYDGLVGQLKGKADQSVPAVGFAMGMERLLLLLEQV 323
+ G+V GGRYDGLVG K + VP VG ++G+ER+ ++EQ
Sbjct 353 VAPETSNEAPTEECVTVGSVAGGGRYDGLVGMFDPKG-RKVPCVGVSIGIERIFSIMEQK 411
Query 324 EQA--EVVRDCDVFLVAESAFQGHALVLAEQIRDQFEGLASTIRVKTGSQGSMK--SQMK 379
+A E +R +V ++ +A + +L E++R E + I+ + + S K SQ++
Sbjct 412 AEASTEKIRTTEVQVMVAAAQKN---LLEERLRLITELWNAGIKAELMYKKSPKLLSQLQ 468
Query 380 KADQSGAHYAVILGEREWTTQELTVKELATSEQSQVAISELVPFLVKK 427
++SG ILGE+E + ++ +AT ++ ++ ++L+ + K+
Sbjct 469 HCEESGIPLVAILGEQELKNGVVKLRNVATRDEVDISRADLIAEIKKR 516
>P49590 Histidine--tRNA ligase, mitochondrial [Homo sapiens]
Length=506
Score = 87.0 bits (214), Expect = 2e-21
Identities = 114/465 (25%), Positives = 203/465 (44%), Gaps = 62/465 (13%)
Query 8 KGFNDVLPTQTAAWRRLEQHLASLMDAYGYQQIRLPIVEQTGLFKRAIGDATDIVEKEMY 67
KG D+ P ++ + S +G + + P E G+ + + MY
Sbjct 61 KGTRDLSPQHMVVREKILDLVISCFKRHGAKGMDTPAFELKETLTEKYGEDSGL----MY 116
Query 68 TFFDKGTPPESLTLRPEGTAGCVRAMLEHNLLRGATPRVWYVGPMFRYEKPQ--KGRYRQ 125
D+G E L+LR + T R + + + + + ++VG ++R E P +GRYR+
Sbjct 117 DLKDQGG--ELLSLRYDLTVPFARYLAMNKVKK---MKRYHVGKVWRRESPTIVQGRYRE 171
Query 126 FHQFGVETFGVATPDI-DAELILMTARLWKRM----------------------GVSE-K 161
F Q + G P I DAE + + + + GV E K
Sbjct 172 FCQCDFDIAGQFDPMIPDAECLKIMCEILSGLQLGDFLIKVNDRRIVDGMFAVCGVPESK 231
Query 162 VQLELNTLGEIDERAAYRTALVEFLTQHKEALDEDSQRRLGTNPLRILDSKVESTQKILE 221
+ +++ ++D + A++ E + K+ L + R+G V +++ +
Sbjct 232 FRAICSSIDKLD-KMAWKDVRHEMVV--KKGLAPEVADRIGDYVQ--CHGGVSLVEQMFQ 286
Query 222 NAPKLHDFLQE-DSLAHFNQLQEYLTHAGVSFVIN--QKLVRGLDYYNKTVFE----WTT 274
+ P+L Q + L L EYLT G++ I+ L RGLDYY ++E T
Sbjct 287 D-PRLSQNKQALEGLGDLKLLFEYLTLFGIADKISFDLSLARGLDYYTGVIYEAVLLQTP 345
Query 275 TALGSQ----GTVCAGGRYDGLVGQLKGKADQSVPAVGFAMGMERLLLLLEQ--VEQAEV 328
T G + G+V AGGRYDGLVG K VP VG ++G+ER+ ++EQ + E
Sbjct 346 TQAGEEPLNVGSVAAGGRYDGLVGMFDPKG-HKVPCVGLSIGVERIFYIVEQRMKTKGEK 404
Query 329 VR--DCDVFLVA-ESAFQGHALVLAEQIRDQFEGLASTIRVKTGSQGSMKSQMKKADQSG 385
VR + VF+ + F L L ++ D G+ + + K + + +Q+ + +G
Sbjct 405 VRTTETQVFVATPQKNFLQERLKLIAELWD--SGIKAEMLYKNNPK--LLTQLHYCESTG 460
Query 386 AHYAVILGEREWTTQELTVKELATSEQSQVAISELVPFLVKKFEK 430
VI+GE+E + ++ +A+ E+ + V + K+ +
Sbjct 461 IPLVVIIGEQELKEGVIKIRSVASREEVAIKRENFVAEIQKRLSE 505
Lambda K H a alpha
0.320 0.135 0.388 0.792 4.96
Gapped
Lambda K H a alpha sigma
0.267 0.0410 0.140 1.90 42.6 43.6
Effective search space used: 3128706
Database: 588db0f3a8ffe78070ad17fd393114c0.SwissProt.fasta
Posted date: May 9, 2024 5:42 AM
Number of letters in database: 9,390
Number of sequences in database: 21
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Neighboring words threshold: 11
Window for multiple hits: 40
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Data ...
