BLASTP 2.12.0+
Reference: Stephen F. Altschul, Thomas L. Madden, Alejandro A.
Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J.
Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of
protein database search programs", Nucleic Acids Res. 25:3389-3402.
Reference for composition-based statistics: Alejandro A. Schaffer,
L. Aravind, Thomas L. Madden, Sergei Shavirin, John L. Spouge, Yuri
I. Wolf, Eugene V. Koonin, and Stephen F. Altschul (2001),
"Improving the accuracy of PSI-BLAST protein database searches with
composition-based statistics and other refinements", Nucleic Acids
Res. 29:2994-3005.
Database: 898457986823ca98d6cf5d1db8e1f382.SwissProt.fasta
28 sequences; 14,912 total letters
Query= ACIAD0574
Length=528
Score E
Sequences producing significant alignments: (Bits) Value
Q8RBH4 Histidine ammonia-lyase [Caldanaerobacter subterraneus sub... 279 1e-90
C5D4K1 Histidine ammonia-lyase [Geobacillus sp. (strain WCH70)] 272 5e-88
A6QD47 Histidine ammonia-lyase [Staphylococcus aureus (strain New... 271 6e-88
Q5HJY8 Histidine ammonia-lyase [Staphylococcus aureus (strain COL)] 271 6e-88
Q2G2P7 Histidine ammonia-lyase [Staphylococcus aureus (strain NCT... 271 6e-88
Q2FKP8 Histidine ammonia-lyase [Staphylococcus aureus (strain USA... 271 6e-88
A8YYT1 Histidine ammonia-lyase [Staphylococcus aureus (strain USA... 271 6e-88
Q2YUR3 Histidine ammonia-lyase [Staphylococcus aureus (strain bov... 271 6e-88
Q5L310 Histidine ammonia-lyase [Geobacillus kaustophilus (strain ... 270 4e-87
Q4A173 Histidine ammonia-lyase [Staphylococcus saprophyticus subs... 269 4e-87
A5INP9 Histidine ammonia-lyase [Staphylococcus aureus (strain JH9)] 269 5e-87
A6TXF8 Histidine ammonia-lyase [Staphylococcus aureus (strain JH1)] 269 5e-87
Q8NYY3 Histidine ammonia-lyase [Staphylococcus aureus (strain MW2)] 269 5e-87
Q6GD82 Histidine ammonia-lyase [Staphylococcus aureus (strain MSS... 269 5e-87
P64416 Histidine ammonia-lyase [Staphylococcus aureus (strain N315)] 269 5e-87
Q6GKT7 Histidine ammonia-lyase [Staphylococcus aureus (strain MRS... 267 3e-86
A8MF64 Histidine ammonia-lyase [Alkaliphilus oremlandii (strain O... 267 3e-86
A7ZAE4 Histidine ammonia-lyase [Bacillus velezensis (strain DSM 2... 263 1e-84
P42357 Histidine ammonia-lyase [Homo sapiens] 266 2e-84
P10944 Histidine ammonia-lyase [Bacillus subtilis (strain 168)] 260 1e-83
Q20502 Histidine ammonia-lyase [Caenorhabditis elegans] 264 3e-83
Q8GMG0 MIO-dependent tyrosine 2,3-aminomutase [Streptomyces globi... 259 6e-83
P35492 Histidine ammonia-lyase [Mus musculus] 262 9e-83
P21213 Histidine ammonia-lyase [Rattus norvegicus] 262 9e-83
Q0VZ68 Tyrosine 2,3-aminomutase [Chondromyces crocatus] 250 2e-79
Q93TX3 Histidine ammonia-lyase [Stigmatella aurantiaca] 244 2e-77
Q3M5Z3 Phenylalanine ammonia-lyase [Trichormus variabilis (strain... 239 5e-75
Q3IWB0 Tyrosine ammonia-lyase [Cereibacter sphaeroides (strain AT... 238 9e-75
>Q8RBH4 Histidine ammonia-lyase [Caldanaerobacter subterraneus
subsp. tengcongensis (strain DSM 15242 / JCM 11007 / NBRC 100824
/ MB4)]
Length=508
Score = 279 bits (713), Expect = 1e-90
Identities = 172/487 (35%), Positives = 276/487 (57%), Gaps = 9/487 (2%)
Query 20 LSIEDVVRVAQAKCRVALPEQQDWRDLIQKGADFLDTLLQEEGVIYGVTTGYGDSCLVEV 79
L+IEDVV+VA+ K V L E ++ I + +D ++E V+YG+TTG+G V +
Sbjct 11 LTIEDVVKVARDKWEVVLSEVA--KERIVHSREIVDRYVKEGKVVYGITTGFGKFSDVVI 68
Query 80 PTHQVHELPLQLSRFHGCGLGQNLDLVTARAVVITRLCSLARGYSGVSLALLERLVWLLN 139
L L H C +G L RA+++ R +LA+G+SGV L +E L+ ++N
Sbjct 69 SKEDTEALQKNLIMSHSCAVGDPLPEEVVRAIMLLRANALAKGFSGVRLETVETLIEMIN 128
Query 140 ENVIPVIPSEGSVGASGDLTPLSYIAGVLVGEREVYYQGKIIPVQQVYQQKAIQPLTLRP 199
+NV+PVIP +GS+GASGDL PL+++ V++G E +Y G+ + ++ ++ I +TL
Sbjct 129 KNVVPVIPEKGSLGASGDLAPLAHMVLVMIGRGEAFYAGERVSGEEAMRRAGIPTITLSS 188
Query 200 KEGLALMNGTAVMTAIACLNYKRAEQIAQTATLVTAINVLALEGNPTHFDEVLFAQKPHT 259
KEGLAL+NGT VM+A+ CLN A++I A V +I + AL G FD+ + +PH
Sbjct 189 KEGLALINGTQVMSALGCLNVYDAKRIIAVADAVASITLEALRGIIDAFDDRVQMVRPHK 248
Query 260 GQQKIAAQLRDWL-NSEVQTAHQSPRLQDRYSLRCAPHVIGVFEDSKVWLRQFIENELNS 318
GQ A +R + SE+ T R+QD Y+LRC P V G D+ ++ + + E+NS
Sbjct 249 GQIVSAKNVRKMVEGSELITRQGEIRVQDAYTLRCIPQVHGAVRDAISYIERVLGVEINS 308
Query 319 SNDNPLIDPVNLRVLHGGHFYGGHIAQAMDSLKIMIANIADLMDRQLAQLVDHKMNHGLP 378
+ DNPLI P + V+ GG+F+G +A AMD L I ++ IA++ +R++ +LV++++N LP
Sbjct 309 ATDNPLIFPDDGEVISGGNFHGEPVALAMDFLSIALSEIANISERRIERLVNYQLN-DLP 367
Query 379 RNLTGATAERLPLNHGFKAVQIGVSAWTAEALKQTLSASIFSRSTECHNQDKVSMGTIAA 438
LT E+ LN G Q ++ +E + AS+ S + + +D VSMGTIAA
Sbjct 368 PFLT----EKGGLNSGMMIAQYTAASLVSENKVLSHPASVDSIPSSANQEDHVSMGTIAA 423
Query 439 RDATRIIVLTEQVMAALCCASIQAIHLKQLAQQLSPTLRAFSAWTLHSLALVIEDRPLQT 498
R A ++ V+A + QA+ ++ ++ T R + + ++EDR L
Sbjct 424 RKAREVLKNVTTVLAIELLTASQALEFRKGFKRGKGTDRIYRL-VREKVNPLVEDRELYI 482
Query 499 ELQQIVD 505
++ D
Sbjct 483 DINACFD 489
>C5D4K1 Histidine ammonia-lyase [Geobacillus sp. (strain WCH70)]
Length=508
Score = 272 bits (695), Expect = 5e-88
Identities = 163/463 (35%), Positives = 267/463 (58%), Gaps = 8/463 (2%)
Query 20 LSIEDVVRVAQAKCRVALPEQQDWRDLIQKGADFLDTLLQEEGVIYGVTTGYGDSCLVEV 79
L++E+V RV V ++ + +++ ++ ++ + V+YG+ TG+G V +
Sbjct 9 LTLEEVKRVLYRDELVIASKES--MEAVERSRKAVEEIVANKNVVYGINTGFGKFSDVLI 66
Query 80 PTHQVHELPLQLSRFHGCGLGQNLDLVTARAVVITRLCSLARGYSGVSLALLERLVWLLN 139
V EL L H CG+G+ +RA+++ R +L +GYSGV ++ERL+ LLN
Sbjct 67 AAGDVEELQWNLIHSHACGVGEPFPEEVSRAMLLLRANALLKGYSGVRPIVIERLLDLLN 126
Query 140 ENVIPVIPSEGSVGASGDLTPLSYIAGVLVGEREVYYQGKIIPVQQVYQQKAIQPLTLRP 199
+ PVIP +GS+GASGDL PLS++A L+GE EV+Y+GK +P + + I P+TL+
Sbjct 127 AKIHPVIPQQGSLGASGDLAPLSHLALALLGEGEVFYRGKRVPAIEALSAEGIAPITLKA 186
Query 200 KEGLALMNGTAVMTAIACLNYKRAEQIAQTATLVTAINVLALEGNPTHFDEVLFAQKPHT 259
KEGLAL+NGT MTA+ + Y AEQ+A + + A+ + L G FDE + + +
Sbjct 187 KEGLALINGTQAMTAMGVVVYLEAEQLAYESEAIAAMTIEGLRGIIDAFDEHVHLVRGYR 246
Query 260 GQQKIAAQLRDWL-NSEVQTAHQSPRLQDRYSLRCAPHVIGVFEDSKVWLRQFIENELNS 318
Q ++AA++RD+L S++ T R+QD YSLRC P V G ++++ +E E+N+
Sbjct 247 QQVEVAARIRDYLAGSKLTTRQGELRVQDAYSLRCIPQVHGASWQVLDYVKEKLEIEINA 306
Query 319 SNDNPLIDPVNLRVLHGGHFYGGHIAQAMDSLKIMIANIADLMDRQLAQLVDHKMNHGLP 378
+ DNPLI +V+ GG+F+G IA AMD +KI IA +A++ +R++ +LV+ ++N LP
Sbjct 307 ATDNPLIFEGGAKVISGGNFHGQPIAFAMDFMKIAIAELANISERRIERLVNPQLN-DLP 365
Query 379 RNLTGATAERLPLNHGFKAVQIGVSAWTAEALKQTLSASIFSRSTECHNQDKVSMGTIAA 438
L+ A L G +Q ++ +E AS+ S + + +D VSMGTIA+
Sbjct 366 PFLSPAPG----LQSGAMIMQYTAASLVSENKTFAHPASVDSIPSSANQEDHVSMGTIAS 421
Query 439 RDATRIIVLTEQVMAALCCASIQAIHLKQLAQQLSPTLRAFSA 481
R A I+ T +V+A ++QA+ + + T + + A
Sbjct 422 RHAYAILQNTRRVLAIELICAMQAVEYRGVENMAPKTRKLYEA 464
>A6QD47 Histidine ammonia-lyase [Staphylococcus aureus (strain
Newman)]
Length=504
Score = 271 bits (694), Expect = 6e-88
Identities = 165/469 (35%), Positives = 269/469 (57%), Gaps = 10/469 (2%)
Query 12 TLTVGLEPLSIEDVVRVAQAKCRVALPEQQDWRDLIQKGADFLDTLLQEEGVIYGVTTGY 71
TL + E L+IED+ Q + ++ + + D + ++K ++ +++ E +YG+TTG+
Sbjct 2 TLYLDGETLTIEDIKSFLQQQSKIEIID--DALERVKKSRAVVERIIENEETVYGITTGF 59
Query 72 GDSCLVEVPTHQVHELPLQLSRFHGCGLGQNLDLVTARAVVITRLCSLARGYSGVSLALL 131
G V + Q +EL + L R H CGLG+ A ++I RL +L +G+SG +L L+
Sbjct 60 GLFSDVRIDPTQYNELQVNLIRSHACGLGEPFSKEVALVMMILRLNTLLKGHSGATLELV 119
Query 132 ERLVWLLNENVIPVIPSEGSVGASGDLTPLSYIAGVLVGEREVYYQGKIIPVQQVYQQKA 191
+L + +NE +IP+IP +GS+GASGDL PLS++A L+GE +V Y+G+ V ++
Sbjct 120 RQLQFFINERIIPIIPQQGSLGASGDLAPLSHLALALIGEGKVLYRGEEKDSDDVLRELN 179
Query 192 IQPLTLRPKEGLALMNGTAVMTAIACLNYKRAEQIAQTATLVTAINVLALEGNPTHFDEV 251
QPL L+ KEGLAL+NGT MTA ++Y AE + + + A+ +L G +
Sbjct 180 RQPLNLQAKEGLALINGTQAMTAQGVISYIEAEDLGYQSEWIAALTHQSLNGIIDAYRHD 239
Query 252 LFAQKPHTGQQKIAAQLRDWLNSEVQTAHQSP-RLQDRYSLRCAPHVIGVFEDSKVWLRQ 310
+ A + Q +AA++RDWL T QS R+QD Y+LRC P + G +++Q
Sbjct 240 VHAVRNFQEQINVAARMRDWLEGSTLTTRQSEIRVQDAYTLRCIPQIHGASFQVFNYVKQ 299
Query 311 FIENELNSSNDNPLI--DPVNLRVLHGGHFYGGHIAQAMDSLKIMIANIADLMDRQLAQL 368
+E E+N++NDNPLI + V+ GG+F+G IA A+D LK+ ++ +A++ +R+L +L
Sbjct 300 QLEFEMNAANDNPLIFEEANETFVISGGNFHGQPIAFALDHLKLGVSELANVSERRLERL 359
Query 369 VDHKMNHGLPRNLTGATAERLPLNHGFKAVQIGVSAWTAEALKQTLSASIFSRSTECHNQ 428
V+ ++N LP L+ L G +Q ++ +E AS+ S ++ + +
Sbjct 360 VNPQLNGDLPAFLSPEPG----LQSGAMIMQYAAASLVSENKTLAHPASVDSITSSANQE 415
Query 429 DKVSMGTIAARDATRIIVLTEQVMAALCCASIQAIHLKQLAQQLSPTLR 477
D VSMGT AAR +II +V+A C ++QA LK + + LSP R
Sbjct 416 DHVSMGTTAARHGYQIIENARRVLAIECVIALQAAELKGV-EGLSPKTR 463
>Q5HJY8 Histidine ammonia-lyase [Staphylococcus aureus (strain
COL)]
Length=504
Score = 271 bits (694), Expect = 6e-88
Identities = 165/469 (35%), Positives = 269/469 (57%), Gaps = 10/469 (2%)
Query 12 TLTVGLEPLSIEDVVRVAQAKCRVALPEQQDWRDLIQKGADFLDTLLQEEGVIYGVTTGY 71
TL + E L+IED+ Q + ++ + + D + ++K ++ +++ E +YG+TTG+
Sbjct 2 TLYLDGETLTIEDIKSFLQQQSKIEIID--DALERVKKSRAVVERIIENEETVYGITTGF 59
Query 72 GDSCLVEVPTHQVHELPLQLSRFHGCGLGQNLDLVTARAVVITRLCSLARGYSGVSLALL 131
G V + Q +EL + L R H CGLG+ A ++I RL +L +G+SG +L L+
Sbjct 60 GLFSDVRIDPTQYNELQVNLIRSHACGLGEPFSKEVALVMMILRLNTLLKGHSGATLELV 119
Query 132 ERLVWLLNENVIPVIPSEGSVGASGDLTPLSYIAGVLVGEREVYYQGKIIPVQQVYQQKA 191
+L + +NE +IP+IP +GS+GASGDL PLS++A L+GE +V Y+G+ V ++
Sbjct 120 RQLQFFINERIIPIIPQQGSLGASGDLAPLSHLALALIGEGKVLYRGEEKDSDDVLRELN 179
Query 192 IQPLTLRPKEGLALMNGTAVMTAIACLNYKRAEQIAQTATLVTAINVLALEGNPTHFDEV 251
QPL L+ KEGLAL+NGT MTA ++Y AE + + + A+ +L G +
Sbjct 180 RQPLNLQAKEGLALINGTQAMTAQGVISYIEAEDLGYQSEWIAALTHQSLNGIIDAYRHD 239
Query 252 LFAQKPHTGQQKIAAQLRDWLNSEVQTAHQSP-RLQDRYSLRCAPHVIGVFEDSKVWLRQ 310
+ A + Q +AA++RDWL T QS R+QD Y+LRC P + G +++Q
Sbjct 240 VHAVRNFQEQINVAARMRDWLEGSTLTTRQSEIRVQDAYTLRCIPQIHGASFQVFNYVKQ 299
Query 311 FIENELNSSNDNPLI--DPVNLRVLHGGHFYGGHIAQAMDSLKIMIANIADLMDRQLAQL 368
+E E+N++NDNPLI + V+ GG+F+G IA A+D LK+ ++ +A++ +R+L +L
Sbjct 300 QLEFEMNAANDNPLIFEEANETFVISGGNFHGQPIAFALDHLKLGVSELANVSERRLERL 359
Query 369 VDHKMNHGLPRNLTGATAERLPLNHGFKAVQIGVSAWTAEALKQTLSASIFSRSTECHNQ 428
V+ ++N LP L+ L G +Q ++ +E AS+ S ++ + +
Sbjct 360 VNPQLNGDLPAFLSPEPG----LQSGAMIMQYAAASLVSENKTLAHPASVDSITSSANQE 415
Query 429 DKVSMGTIAARDATRIIVLTEQVMAALCCASIQAIHLKQLAQQLSPTLR 477
D VSMGT AAR +II +V+A C ++QA LK + + LSP R
Sbjct 416 DHVSMGTTAARHGYQIIENARRVLAIECVIALQAAELKGV-EGLSPKTR 463
>Q2G2P7 Histidine ammonia-lyase [Staphylococcus aureus (strain
NCTC 8325 / PS 47)]
Length=504
Score = 271 bits (694), Expect = 6e-88
Identities = 165/469 (35%), Positives = 269/469 (57%), Gaps = 10/469 (2%)
Query 12 TLTVGLEPLSIEDVVRVAQAKCRVALPEQQDWRDLIQKGADFLDTLLQEEGVIYGVTTGY 71
TL + E L+IED+ Q + ++ + + D + ++K ++ +++ E +YG+TTG+
Sbjct 2 TLYLDGETLTIEDIKSFLQQQSKIEIID--DALERVKKSRAVVERIIENEETVYGITTGF 59
Query 72 GDSCLVEVPTHQVHELPLQLSRFHGCGLGQNLDLVTARAVVITRLCSLARGYSGVSLALL 131
G V + Q +EL + L R H CGLG+ A ++I RL +L +G+SG +L L+
Sbjct 60 GLFSDVRIDPTQYNELQVNLIRSHACGLGEPFSKEVALVMMILRLNTLLKGHSGATLELV 119
Query 132 ERLVWLLNENVIPVIPSEGSVGASGDLTPLSYIAGVLVGEREVYYQGKIIPVQQVYQQKA 191
+L + +NE +IP+IP +GS+GASGDL PLS++A L+GE +V Y+G+ V ++
Sbjct 120 RQLQFFINERIIPIIPQQGSLGASGDLAPLSHLALALIGEGKVLYRGEEKDSDDVLRELN 179
Query 192 IQPLTLRPKEGLALMNGTAVMTAIACLNYKRAEQIAQTATLVTAINVLALEGNPTHFDEV 251
QPL L+ KEGLAL+NGT MTA ++Y AE + + + A+ +L G +
Sbjct 180 RQPLNLQAKEGLALINGTQAMTAQGVISYIEAEDLGYQSEWIAALTHQSLNGIIDAYRHD 239
Query 252 LFAQKPHTGQQKIAAQLRDWLNSEVQTAHQSP-RLQDRYSLRCAPHVIGVFEDSKVWLRQ 310
+ A + Q +AA++RDWL T QS R+QD Y+LRC P + G +++Q
Sbjct 240 VHAVRNFQEQINVAARMRDWLEGSTLTTRQSEIRVQDAYTLRCIPQIHGASFQVFNYVKQ 299
Query 311 FIENELNSSNDNPLI--DPVNLRVLHGGHFYGGHIAQAMDSLKIMIANIADLMDRQLAQL 368
+E E+N++NDNPLI + V+ GG+F+G IA A+D LK+ ++ +A++ +R+L +L
Sbjct 300 QLEFEMNAANDNPLIFEEANETFVISGGNFHGQPIAFALDHLKLGVSELANVSERRLERL 359
Query 369 VDHKMNHGLPRNLTGATAERLPLNHGFKAVQIGVSAWTAEALKQTLSASIFSRSTECHNQ 428
V+ ++N LP L+ L G +Q ++ +E AS+ S ++ + +
Sbjct 360 VNPQLNGDLPAFLSPEPG----LQSGAMIMQYAAASLVSENKTLAHPASVDSITSSANQE 415
Query 429 DKVSMGTIAARDATRIIVLTEQVMAALCCASIQAIHLKQLAQQLSPTLR 477
D VSMGT AAR +II +V+A C ++QA LK + + LSP R
Sbjct 416 DHVSMGTTAARHGYQIIENARRVLAIECVIALQAAELKGV-EGLSPKTR 463
>Q2FKP8 Histidine ammonia-lyase [Staphylococcus aureus (strain
USA300)]
Length=504
Score = 271 bits (694), Expect = 6e-88
Identities = 165/469 (35%), Positives = 269/469 (57%), Gaps = 10/469 (2%)
Query 12 TLTVGLEPLSIEDVVRVAQAKCRVALPEQQDWRDLIQKGADFLDTLLQEEGVIYGVTTGY 71
TL + E L+IED+ Q + ++ + + D + ++K ++ +++ E +YG+TTG+
Sbjct 2 TLYLDGETLTIEDIKSFLQQQSKIEIID--DALERVKKSRAVVERIIENEETVYGITTGF 59
Query 72 GDSCLVEVPTHQVHELPLQLSRFHGCGLGQNLDLVTARAVVITRLCSLARGYSGVSLALL 131
G V + Q +EL + L R H CGLG+ A ++I RL +L +G+SG +L L+
Sbjct 60 GLFSDVRIDPTQYNELQVNLIRSHACGLGEPFSKEVALVMMILRLNTLLKGHSGATLELV 119
Query 132 ERLVWLLNENVIPVIPSEGSVGASGDLTPLSYIAGVLVGEREVYYQGKIIPVQQVYQQKA 191
+L + +NE +IP+IP +GS+GASGDL PLS++A L+GE +V Y+G+ V ++
Sbjct 120 RQLQFFINERIIPIIPQQGSLGASGDLAPLSHLALALIGEGKVLYRGEEKDSDDVLRELN 179
Query 192 IQPLTLRPKEGLALMNGTAVMTAIACLNYKRAEQIAQTATLVTAINVLALEGNPTHFDEV 251
QPL L+ KEGLAL+NGT MTA ++Y AE + + + A+ +L G +
Sbjct 180 RQPLNLQAKEGLALINGTQAMTAQGVISYIEAEDLGYQSEWIAALTHQSLNGIIDAYRHD 239
Query 252 LFAQKPHTGQQKIAAQLRDWLNSEVQTAHQSP-RLQDRYSLRCAPHVIGVFEDSKVWLRQ 310
+ A + Q +AA++RDWL T QS R+QD Y+LRC P + G +++Q
Sbjct 240 VHAVRNFQEQINVAARMRDWLEGSTLTTRQSEIRVQDAYTLRCIPQIHGASFQVFNYVKQ 299
Query 311 FIENELNSSNDNPLI--DPVNLRVLHGGHFYGGHIAQAMDSLKIMIANIADLMDRQLAQL 368
+E E+N++NDNPLI + V+ GG+F+G IA A+D LK+ ++ +A++ +R+L +L
Sbjct 300 QLEFEMNAANDNPLIFEEANETFVISGGNFHGQPIAFALDHLKLGVSELANVSERRLERL 359
Query 369 VDHKMNHGLPRNLTGATAERLPLNHGFKAVQIGVSAWTAEALKQTLSASIFSRSTECHNQ 428
V+ ++N LP L+ L G +Q ++ +E AS+ S ++ + +
Sbjct 360 VNPQLNGDLPAFLSPEPG----LQSGAMIMQYAAASLVSENKTLAHPASVDSITSSANQE 415
Query 429 DKVSMGTIAARDATRIIVLTEQVMAALCCASIQAIHLKQLAQQLSPTLR 477
D VSMGT AAR +II +V+A C ++QA LK + + LSP R
Sbjct 416 DHVSMGTTAARHGYQIIENARRVLAIECVIALQAAELKGV-EGLSPKTR 463
>A8YYT1 Histidine ammonia-lyase [Staphylococcus aureus (strain
USA300 / TCH1516)]
Length=504
Score = 271 bits (694), Expect = 6e-88
Identities = 165/469 (35%), Positives = 269/469 (57%), Gaps = 10/469 (2%)
Query 12 TLTVGLEPLSIEDVVRVAQAKCRVALPEQQDWRDLIQKGADFLDTLLQEEGVIYGVTTGY 71
TL + E L+IED+ Q + ++ + + D + ++K ++ +++ E +YG+TTG+
Sbjct 2 TLYLDGETLTIEDIKSFLQQQSKIEIID--DALERVKKSRAVVERIIENEETVYGITTGF 59
Query 72 GDSCLVEVPTHQVHELPLQLSRFHGCGLGQNLDLVTARAVVITRLCSLARGYSGVSLALL 131
G V + Q +EL + L R H CGLG+ A ++I RL +L +G+SG +L L+
Sbjct 60 GLFSDVRIDPTQYNELQVNLIRSHACGLGEPFSKEVALVMMILRLNTLLKGHSGATLELV 119
Query 132 ERLVWLLNENVIPVIPSEGSVGASGDLTPLSYIAGVLVGEREVYYQGKIIPVQQVYQQKA 191
+L + +NE +IP+IP +GS+GASGDL PLS++A L+GE +V Y+G+ V ++
Sbjct 120 RQLQFFINERIIPIIPQQGSLGASGDLAPLSHLALALIGEGKVLYRGEEKDSDDVLRELN 179
Query 192 IQPLTLRPKEGLALMNGTAVMTAIACLNYKRAEQIAQTATLVTAINVLALEGNPTHFDEV 251
QPL L+ KEGLAL+NGT MTA ++Y AE + + + A+ +L G +
Sbjct 180 RQPLNLQAKEGLALINGTQAMTAQGVISYIEAEDLGYQSEWIAALTHQSLNGIIDAYRHD 239
Query 252 LFAQKPHTGQQKIAAQLRDWLNSEVQTAHQSP-RLQDRYSLRCAPHVIGVFEDSKVWLRQ 310
+ A + Q +AA++RDWL T QS R+QD Y+LRC P + G +++Q
Sbjct 240 VHAVRNFQEQINVAARMRDWLEGSTLTTRQSEIRVQDAYTLRCIPQIHGASFQVFNYVKQ 299
Query 311 FIENELNSSNDNPLI--DPVNLRVLHGGHFYGGHIAQAMDSLKIMIANIADLMDRQLAQL 368
+E E+N++NDNPLI + V+ GG+F+G IA A+D LK+ ++ +A++ +R+L +L
Sbjct 300 QLEFEMNAANDNPLIFEEANETFVISGGNFHGQPIAFALDHLKLGVSELANVSERRLERL 359
Query 369 VDHKMNHGLPRNLTGATAERLPLNHGFKAVQIGVSAWTAEALKQTLSASIFSRSTECHNQ 428
V+ ++N LP L+ L G +Q ++ +E AS+ S ++ + +
Sbjct 360 VNPQLNGDLPAFLSPEPG----LQSGAMIMQYAAASLVSENKTLAHPASVDSITSSANQE 415
Query 429 DKVSMGTIAARDATRIIVLTEQVMAALCCASIQAIHLKQLAQQLSPTLR 477
D VSMGT AAR +II +V+A C ++QA LK + + LSP R
Sbjct 416 DHVSMGTTAARHGYQIIENARRVLAIECVIALQAAELKGV-EGLSPKTR 463
>Q2YUR3 Histidine ammonia-lyase [Staphylococcus aureus (strain
bovine RF122 / ET3-1)]
Length=504
Score = 271 bits (694), Expect = 6e-88
Identities = 167/469 (36%), Positives = 272/469 (58%), Gaps = 10/469 (2%)
Query 12 TLTVGLEPLSIEDVVRVAQAKCRVALPEQQDWRDLIQKGADFLDTLLQEEGVIYGVTTGY 71
TL + E L+IED+ Q + +V + + D + ++K ++ +++ E +YG+TTG+
Sbjct 2 TLYLDGETLTIEDIKSFLQQQSKVEIID--DALERVKKSRAVVERIIENEETVYGITTGF 59
Query 72 GDSCLVEVPTHQVHELPLQLSRFHGCGLGQNLDLVTARAVVITRLCSLARGYSGVSLALL 131
G V + Q +EL + L R H CGLG+ A ++I RL +L +G+SG +L L+
Sbjct 60 GLFSDVRIDPTQYNELQVNLIRSHACGLGEPFSKEVALVMMILRLNTLLKGHSGATLELV 119
Query 132 ERLVWLLNENVIPVIPSEGSVGASGDLTPLSYIAGVLVGEREVYYQGKIIPVQQVYQQKA 191
+L + +NE +IP+IP +GS+GASGDL PLS++A L+GE +V ++G+ V ++
Sbjct 120 RQLQFFINERIIPIIPQQGSLGASGDLAPLSHLALALIGEGKVLHRGEEKDSDDVLRELN 179
Query 192 IQPLTLRPKEGLALMNGTAVMTAIACLNYKRAEQIAQTATLVTAINVLALEGNPTHFDEV 251
QPL L+ KEGLAL+NGT MTA ++Y AE + + + A+ +L G +
Sbjct 180 RQPLNLQAKEGLALINGTQAMTAQGVISYIEAEDLGYQSEWIAALTHQSLNGIIDAYRHD 239
Query 252 LFAQKPHTGQQKIAAQLRDWLNSEVQTAHQSP-RLQDRYSLRCAPHVIGVFEDSKVWLRQ 310
+ A + Q +AA++RDWL T Q+ R+QD Y+LRC P + G +++Q
Sbjct 240 VHAVRNFQEQINVAARMRDWLEGSTLTTRQAEIRVQDAYTLRCIPQIHGASFQVFNYVKQ 299
Query 311 FIENELNSSNDNPLI-DPVN-LRVLHGGHFYGGHIAQAMDSLKIMIANIADLMDRQLAQL 368
+E E+N++NDNPLI + VN V+ GG+F+G IA A+D LK+ ++ +A++ +R+L +L
Sbjct 300 QLEFEMNAANDNPLIFEEVNETFVISGGNFHGQPIAFALDHLKLGVSELANVSERRLERL 359
Query 369 VDHKMNHGLPRNLTGATAERLPLNHGFKAVQIGVSAWTAEALKQTLSASIFSRSTECHNQ 428
V+ ++N LP L+ L G +Q ++ +E AS+ S ++ + +
Sbjct 360 VNPQLNGDLPAFLSPEPG----LQSGAMIMQYAAASLVSENKTLAHPASVDSITSSANQE 415
Query 429 DKVSMGTIAARDATRIIVLTEQVMAALCCASIQAIHLKQLAQQLSPTLR 477
D VSMGT AAR +II T +V+A C ++QA LK + + LSP R
Sbjct 416 DHVSMGTTAARHGYQIIENTRRVLAIECVIALQATELKGV-EGLSPKTR 463
>Q5L310 Histidine ammonia-lyase [Geobacillus kaustophilus (strain
HTA426)]
Length=504
Score = 270 bits (689), Expect = 4e-87
Identities = 163/485 (34%), Positives = 272/485 (56%), Gaps = 9/485 (2%)
Query 20 LSIEDVVRVAQAKCRVALPEQQDWRDLIQKGADFLDTLLQEEGVIYGVTTGYGDSCLVEV 79
L+I++V RV + RVA E+ ++K ++ + IYGV TG+G V +
Sbjct 9 LTIDEVRRVVYERERVAADEES--MRAVEKSRAAVEQAISNGRTIYGVNTGFGKLADVRI 66
Query 80 PTHQVHELPLQLSRFHGCGLGQNLDLVTARAVVITRLCSLARGYSGVSLALLERLVWLLN 139
+ +L + L R H C +G+ RA+++ R +L +GYSGV A++E+L+ LN
Sbjct 67 EGSDLEQLQINLLRSHACAVGEPFAEDVVRAMLLLRANALLKGYSGVRPAVIEQLLAFLN 126
Query 140 ENVIPVIPSEGSVGASGDLTPLSYIAGVLVGEREVYYQGKIIPVQQVYQQKAIQPLTLRP 199
+ P++P +GS+GASGDL PL+++A GE E YQG+ +P Q Q I PL+L+
Sbjct 127 TGIHPIVPQQGSLGASGDLAPLAHLALAFAGEGEAMYQGRRMPAAQALSQAGISPLSLQE 186
Query 200 KEGLALMNGTAVMTAIACLNYKRAEQIAQTATLVTAINVLALEGNPTHFDEVLFAQKPHT 259
KEGLAL+NGT VMTA+ L Y AEQ+A + + A+ + AL G FD + A +
Sbjct 187 KEGLALINGTQVMTAVGALAYLEAEQLAYDSEWIAALTIEALYGIVDAFDARIHAARGFQ 246
Query 260 GQQKIAAQLRDWL-NSEVQTAHQSPRLQDRYSLRCAPHVIGVFEDSKVWLRQFIENELNS 318
Q ++A +LR +L S++ T R+QD YS+RC P V G + ++++ +E E+N+
Sbjct 247 EQVEVAERLRRYLAGSQLTTRQGERRVQDAYSIRCLPQVHGASLRALRYVKETLEIEMNA 306
Query 319 SNDNPLIDPVNLRVLHGGHFYGGHIAQAMDSLKIMIANIADLMDRQLAQLVDHKMNHGLP 378
+ DNPLI + L GG+F+G +A AMD LKI +A +A++ +R++ +LV+ +++ GLP
Sbjct 307 ATDNPLIF-ADGTALSGGNFHGQPVAIAMDLLKIAVAELANISERRIERLVNPQLSEGLP 365
Query 379 RNLTGATAERLPLNHGFKAVQIGVSAWTAEALKQTLSASIFSRSTECHNQDKVSMGTIAA 438
L+ L G +Q ++ +E AS+ S + + +D VSMGT AA
Sbjct 366 PFLSPQPG----LQSGAMIMQYVAASLVSENKTLAHPASVDSIPSSANQEDHVSMGTTAA 421
Query 439 RDATRIIVLTEQVMAALCCASIQAIHLKQLAQQLSPTLRAFSAWTLHSLALVIEDRPLQT 498
R A I+ +V+A ++QA+ + + ++++P+ R F ++ + DR
Sbjct 422 RHAYMIVQNARKVLAIELICALQAVEARGI-ERMAPSTRQFYHKARRIVSSITADRVFSD 480
Query 499 ELQQI 503
+++ +
Sbjct 481 DIEAV 485
>Q4A173 Histidine ammonia-lyase [Staphylococcus saprophyticus
subsp. saprophyticus (strain ATCC 15305 / DSM 20229 / NCIMB
8711 / NCTC 7292 / S-41)]
Length=499
Score = 269 bits (688), Expect = 4e-87
Identities = 162/495 (33%), Positives = 279/495 (56%), Gaps = 10/495 (2%)
Query 12 TLTVGLEPLSIEDVVRVAQAKCRVALPEQQDWRDLIQKGADFLDTLLQEEGVIYGVTTGY 71
TL + E L+I D+ + V + Q+ + ++K ++ +++ + IYG+TTG+
Sbjct 2 TLQLNGEMLTINDIKTFLNKEDTVEVT--QEALERVKKSRQTVEHIIENKETIYGITTGF 59
Query 72 GDSCLVEVPTHQVHELPLQLSRFHGCGLGQNLDLVTARAVVITRLCSLARGYSGVSLALL 131
G V + + ++L + L R H CG+G+ A +++ RL +L +G+SG ++AL+
Sbjct 60 GLFSDVRIDKDEYNQLQVNLIRSHACGVGKPFSEEVALVMMVLRLNTLLKGHSGTTVALV 119
Query 132 ERLVWLLNENVIPVIPSEGSVGASGDLTPLSYIAGVLVGEREVYYQGKIIPVQQVYQQKA 191
E+LV+ +N ++PVIP +GS+GASGDL PLS++A L+GE V+++G+ + + V Q
Sbjct 120 EQLVYYINNRIVPVIPQQGSLGASGDLAPLSHLALALIGEGNVFFKGEEVDSRYVLNQLN 179
Query 192 IQPLTLRPKEGLALMNGTAVMTAIACLNYKRAEQIAQTATLVTAINVLALEGNPTHFDEV 251
P+ L+ KEGLAL+NGT MTA +NY AE + A + A+ AL G ++E
Sbjct 180 RNPIQLQAKEGLALINGTQAMTAQGVINYIEAEALGYQAEWIAALTHQALNGITDAYNEK 239
Query 252 LFAQKPHTGQQKIAAQLRDWLN-SEVQTAHQSPRLQDRYSLRCAPHVIGVFEDSKVWLRQ 310
+ + Q +AA++ DWL+ SE+ T R+QD Y+LRC P + G ++++
Sbjct 240 VHKARNFQEQIDVAARMLDWLDGSELTTTQGDIRVQDAYTLRCIPQIHGASFQVFNYVKE 299
Query 311 FIENELNSSNDNPLI--DPVNLRVLHGGHFYGGHIAQAMDSLKIMIANIADLMDRQLAQL 368
+E E+N++NDNPLI + V+ GG+F+G IA A+D LK+ ++ +A++ +R+L +L
Sbjct 300 KLEFEMNAANDNPLIFDEGDETLVISGGNFHGQPIAFALDFLKLGVSELANVSERRLERL 359
Query 369 VDHKMNHGLPRNLTGATAERLPLNHGFKAVQIGVSAWTAEALKQTLSASIFSRSTECHNQ 428
V+ ++N+GLP L+ L G +Q ++ +E AS+ S + + +
Sbjct 360 VNPQLNNGLPAFLSPQPG----LQSGAMIMQYAAASLVSENKTLAHPASVDSIPSSANQE 415
Query 429 DKVSMGTIAARDATRIIVLTEQVMAALCCASIQAIHLKQLAQQLSPTLRAFSAWTLHSLA 488
D VSMGTIA+R II +V+A ++QA+ K + +LSP H +
Sbjct 416 DHVSMGTIASRHGYHIIENARRVLAIETIIALQAVEYKDI-DKLSPKTYEKYQELRHIVP 474
Query 489 LVIEDRPLQTELQQI 503
+ EDR +++ +
Sbjct 475 SITEDRQFHKDIEAV 489
>A5INP9 Histidine ammonia-lyase [Staphylococcus aureus (strain
JH9)]
Length=504
Score = 269 bits (688), Expect = 5e-87
Identities = 163/469 (35%), Positives = 269/469 (57%), Gaps = 10/469 (2%)
Query 12 TLTVGLEPLSIEDVVRVAQAKCRVALPEQQDWRDLIQKGADFLDTLLQEEGVIYGVTTGY 71
TL + E L+IED+ Q + ++ + + D + ++K ++ +++ E +YG+TTG+
Sbjct 2 TLYLDGETLTIEDIKSFLQQQSKIEIID--DALERVKKSRAVVERIIENEETVYGITTGF 59
Query 72 GDSCLVEVPTHQVHELPLQLSRFHGCGLGQNLDLVTARAVVITRLCSLARGYSGVSLALL 131
G V + Q +EL + L R H CGLG+ A ++I RL +L +G+SG +L L+
Sbjct 60 GLFSDVRIDPTQYNELQVNLIRSHACGLGEPFSKEVALVMMILRLNTLLKGHSGATLELV 119
Query 132 ERLVWLLNENVIPVIPSEGSVGASGDLTPLSYIAGVLVGEREVYYQGKIIPVQQVYQQKA 191
+L + +NE +IP+IP +GS+GASGDL PLS++A L+GE +V Y+G+ V ++
Sbjct 120 RQLQFFINERIIPIIPQQGSLGASGDLAPLSHLALALIGEGKVLYRGEEKDSDDVLRELN 179
Query 192 IQPLTLRPKEGLALMNGTAVMTAIACLNYKRAEQIAQTATLVTAINVLALEGNPTHFDEV 251
QPL L+ KEGLAL+NGT MTA ++Y AE + + + A+ +L G +
Sbjct 180 RQPLNLQAKEGLALINGTQAMTAQGVISYIEAEDLGYQSEWIAALTHQSLNGIIDAYRHD 239
Query 252 LFAQKPHTGQQKIAAQLRDWLNSEVQTAHQSP-RLQDRYSLRCAPHVIGVFEDSKVWLRQ 310
+ + + Q +AA++RDWL T Q+ R+QD Y+LRC P + G +++Q
Sbjct 240 VHSVRNFQEQINVAARMRDWLEGSTLTTRQAEIRVQDAYTLRCIPQIHGASFQVFNYVKQ 299
Query 311 FIENELNSSNDNPLI--DPVNLRVLHGGHFYGGHIAQAMDSLKIMIANIADLMDRQLAQL 368
+E E+N++NDNPLI + V+ GG+F+G IA A+D LK+ ++ +A++ +R+L +L
Sbjct 300 QLEFEMNAANDNPLIFEEANETFVISGGNFHGQPIAFALDHLKLGVSELANVSERRLERL 359
Query 369 VDHKMNHGLPRNLTGATAERLPLNHGFKAVQIGVSAWTAEALKQTLSASIFSRSTECHNQ 428
V+ ++N LP L+ L G +Q ++ +E AS+ S ++ + +
Sbjct 360 VNPQLNGDLPAFLSPEPG----LQSGAMIMQYAAASLVSENKTLAHPASVDSITSSANQE 415
Query 429 DKVSMGTIAARDATRIIVLTEQVMAALCCASIQAIHLKQLAQQLSPTLR 477
D VSMGT AAR +II +V+A C ++QA LK + + LSP R
Sbjct 416 DHVSMGTTAARHGYQIIENARRVLAIECVIALQAAELKGV-EGLSPKTR 463
>A6TXF8 Histidine ammonia-lyase [Staphylococcus aureus (strain
JH1)]
Length=504
Score = 269 bits (688), Expect = 5e-87
Identities = 163/469 (35%), Positives = 269/469 (57%), Gaps = 10/469 (2%)
Query 12 TLTVGLEPLSIEDVVRVAQAKCRVALPEQQDWRDLIQKGADFLDTLLQEEGVIYGVTTGY 71
TL + E L+IED+ Q + ++ + + D + ++K ++ +++ E +YG+TTG+
Sbjct 2 TLYLDGETLTIEDIKSFLQQQSKIEIID--DALERVKKSRAVVERIIENEETVYGITTGF 59
Query 72 GDSCLVEVPTHQVHELPLQLSRFHGCGLGQNLDLVTARAVVITRLCSLARGYSGVSLALL 131
G V + Q +EL + L R H CGLG+ A ++I RL +L +G+SG +L L+
Sbjct 60 GLFSDVRIDPTQYNELQVNLIRSHACGLGEPFSKEVALVMMILRLNTLLKGHSGATLELV 119
Query 132 ERLVWLLNENVIPVIPSEGSVGASGDLTPLSYIAGVLVGEREVYYQGKIIPVQQVYQQKA 191
+L + +NE +IP+IP +GS+GASGDL PLS++A L+GE +V Y+G+ V ++
Sbjct 120 RQLQFFINERIIPIIPQQGSLGASGDLAPLSHLALALIGEGKVLYRGEEKDSDDVLRELN 179
Query 192 IQPLTLRPKEGLALMNGTAVMTAIACLNYKRAEQIAQTATLVTAINVLALEGNPTHFDEV 251
QPL L+ KEGLAL+NGT MTA ++Y AE + + + A+ +L G +
Sbjct 180 RQPLNLQAKEGLALINGTQAMTAQGVISYIEAEDLGYQSEWIAALTHQSLNGIIDAYRHD 239
Query 252 LFAQKPHTGQQKIAAQLRDWLNSEVQTAHQSP-RLQDRYSLRCAPHVIGVFEDSKVWLRQ 310
+ + + Q +AA++RDWL T Q+ R+QD Y+LRC P + G +++Q
Sbjct 240 VHSVRNFQEQINVAARMRDWLEGSTLTTRQAEIRVQDAYTLRCIPQIHGASFQVFNYVKQ 299
Query 311 FIENELNSSNDNPLI--DPVNLRVLHGGHFYGGHIAQAMDSLKIMIANIADLMDRQLAQL 368
+E E+N++NDNPLI + V+ GG+F+G IA A+D LK+ ++ +A++ +R+L +L
Sbjct 300 QLEFEMNAANDNPLIFEEANETFVISGGNFHGQPIAFALDHLKLGVSELANVSERRLERL 359
Query 369 VDHKMNHGLPRNLTGATAERLPLNHGFKAVQIGVSAWTAEALKQTLSASIFSRSTECHNQ 428
V+ ++N LP L+ L G +Q ++ +E AS+ S ++ + +
Sbjct 360 VNPQLNGDLPAFLSPEPG----LQSGAMIMQYAAASLVSENKTLAHPASVDSITSSANQE 415
Query 429 DKVSMGTIAARDATRIIVLTEQVMAALCCASIQAIHLKQLAQQLSPTLR 477
D VSMGT AAR +II +V+A C ++QA LK + + LSP R
Sbjct 416 DHVSMGTTAARHGYQIIENARRVLAIECVIALQAAELKGV-EGLSPKTR 463
>Q8NYY3 Histidine ammonia-lyase [Staphylococcus aureus (strain
MW2)]
Length=504
Score = 269 bits (688), Expect = 5e-87
Identities = 163/469 (35%), Positives = 269/469 (57%), Gaps = 10/469 (2%)
Query 12 TLTVGLEPLSIEDVVRVAQAKCRVALPEQQDWRDLIQKGADFLDTLLQEEGVIYGVTTGY 71
TL + E L+IED+ Q + ++ + + D + ++K ++ +++ E +YG+TTG+
Sbjct 2 TLYLDGETLTIEDIKSFLQQQSKIEIID--DALERVKKSRAVVERIIENEETVYGITTGF 59
Query 72 GDSCLVEVPTHQVHELPLQLSRFHGCGLGQNLDLVTARAVVITRLCSLARGYSGVSLALL 131
G V + Q +EL + L R H CGLG+ A ++I RL +L +G+SG +L L+
Sbjct 60 GLFSDVRIDPTQYNELQVNLIRSHACGLGEPFSKEVALVMMILRLNTLLKGHSGATLELV 119
Query 132 ERLVWLLNENVIPVIPSEGSVGASGDLTPLSYIAGVLVGEREVYYQGKIIPVQQVYQQKA 191
+L + +NE +IP+IP +GS+GASGDL PLS++A L+GE +V Y+G+ V ++
Sbjct 120 RQLQFFINERIIPIIPQQGSLGASGDLAPLSHLALALIGEGKVLYRGEEKDSDDVLRELN 179
Query 192 IQPLTLRPKEGLALMNGTAVMTAIACLNYKRAEQIAQTATLVTAINVLALEGNPTHFDEV 251
QPL L+ KEGLAL+NGT MTA ++Y +E + + + A+ +L G +
Sbjct 180 RQPLNLQAKEGLALINGTQAMTAQGVISYIESEDLGYQSEWIAALTHQSLNGIIDAYRHD 239
Query 252 LFAQKPHTGQQKIAAQLRDWLNSEVQTAHQSP-RLQDRYSLRCAPHVIGVFEDSKVWLRQ 310
+ A + Q +AA++RDWL T Q+ R+QD Y+LRC P + G +++Q
Sbjct 240 VHAVRNFQEQINVAARMRDWLEGSTLTTRQAEIRVQDAYTLRCIPQIHGASFQVFNYVKQ 299
Query 311 FIENELNSSNDNPLI--DPVNLRVLHGGHFYGGHIAQAMDSLKIMIANIADLMDRQLAQL 368
+E E+N++NDNPLI + V+ GG+F+G IA A+D LK+ ++ +A++ +R+L +L
Sbjct 300 QLEFEMNAANDNPLIFEEANETFVISGGNFHGQPIAFALDHLKLGVSELANVSERRLERL 359
Query 369 VDHKMNHGLPRNLTGATAERLPLNHGFKAVQIGVSAWTAEALKQTLSASIFSRSTECHNQ 428
V+ ++N LP L+ L G +Q ++ +E AS+ S ++ + +
Sbjct 360 VNPQLNGDLPAFLSPEPG----LQSGAMIMQYAAASLVSENKTLAHPASVDSITSSANQE 415
Query 429 DKVSMGTIAARDATRIIVLTEQVMAALCCASIQAIHLKQLAQQLSPTLR 477
D VSMGT AAR +II +V+A C ++QA LK + + LSP R
Sbjct 416 DHVSMGTTAARHGYQIIENARRVLAIECVIALQAAELKGV-EGLSPKTR 463
>Q6GD82 Histidine ammonia-lyase [Staphylococcus aureus (strain
MSSA476)]
Length=504
Score = 269 bits (688), Expect = 5e-87
Identities = 163/469 (35%), Positives = 269/469 (57%), Gaps = 10/469 (2%)
Query 12 TLTVGLEPLSIEDVVRVAQAKCRVALPEQQDWRDLIQKGADFLDTLLQEEGVIYGVTTGY 71
TL + E L+IED+ Q + ++ + + D + ++K ++ +++ E +YG+TTG+
Sbjct 2 TLYLDGETLTIEDIKSFLQQQSKIEIID--DALERVKKSRAVVERIIENEETVYGITTGF 59
Query 72 GDSCLVEVPTHQVHELPLQLSRFHGCGLGQNLDLVTARAVVITRLCSLARGYSGVSLALL 131
G V + Q +EL + L R H CGLG+ A ++I RL +L +G+SG +L L+
Sbjct 60 GLFSDVRIDPTQYNELQVNLIRSHACGLGEPFSKEVALVMMILRLNTLLKGHSGATLELV 119
Query 132 ERLVWLLNENVIPVIPSEGSVGASGDLTPLSYIAGVLVGEREVYYQGKIIPVQQVYQQKA 191
+L + +NE +IP+IP +GS+GASGDL PLS++A L+GE +V Y+G+ V ++
Sbjct 120 RQLQFFINERIIPIIPQQGSLGASGDLAPLSHLALALIGEGKVLYRGEEKDSDDVLRELN 179
Query 192 IQPLTLRPKEGLALMNGTAVMTAIACLNYKRAEQIAQTATLVTAINVLALEGNPTHFDEV 251
QPL L+ KEGLAL+NGT MTA ++Y +E + + + A+ +L G +
Sbjct 180 RQPLNLQAKEGLALINGTQAMTAQGVISYIESEDLGYQSEWIAALTHQSLNGIIDAYRHD 239
Query 252 LFAQKPHTGQQKIAAQLRDWLNSEVQTAHQSP-RLQDRYSLRCAPHVIGVFEDSKVWLRQ 310
+ A + Q +AA++RDWL T Q+ R+QD Y+LRC P + G +++Q
Sbjct 240 VHAVRNFQEQINVAARMRDWLEGSTLTTRQAEIRVQDAYTLRCIPQIHGASFQVFNYVKQ 299
Query 311 FIENELNSSNDNPLI--DPVNLRVLHGGHFYGGHIAQAMDSLKIMIANIADLMDRQLAQL 368
+E E+N++NDNPLI + V+ GG+F+G IA A+D LK+ ++ +A++ +R+L +L
Sbjct 300 QLEFEMNAANDNPLIFEEANETFVISGGNFHGQPIAFALDHLKLGVSELANVSERRLERL 359
Query 369 VDHKMNHGLPRNLTGATAERLPLNHGFKAVQIGVSAWTAEALKQTLSASIFSRSTECHNQ 428
V+ ++N LP L+ L G +Q ++ +E AS+ S ++ + +
Sbjct 360 VNPQLNGDLPAFLSPEPG----LQSGAMIMQYAAASLVSENKTLAHPASVDSITSSANQE 415
Query 429 DKVSMGTIAARDATRIIVLTEQVMAALCCASIQAIHLKQLAQQLSPTLR 477
D VSMGT AAR +II +V+A C ++QA LK + + LSP R
Sbjct 416 DHVSMGTTAARHGYQIIENARRVLAIECVIALQAAELKGV-EGLSPKTR 463
>P64416 Histidine ammonia-lyase [Staphylococcus aureus (strain
N315)]
Length=504
Score = 269 bits (688), Expect = 5e-87
Identities = 163/469 (35%), Positives = 269/469 (57%), Gaps = 10/469 (2%)
Query 12 TLTVGLEPLSIEDVVRVAQAKCRVALPEQQDWRDLIQKGADFLDTLLQEEGVIYGVTTGY 71
TL + E L+IED+ Q + ++ + + D + ++K ++ +++ E +YG+TTG+
Sbjct 2 TLYLDGETLTIEDIKSFLQQQSKIEIID--DALERVKKSRAVVERIIENEETVYGITTGF 59
Query 72 GDSCLVEVPTHQVHELPLQLSRFHGCGLGQNLDLVTARAVVITRLCSLARGYSGVSLALL 131
G V + Q +EL + L R H CGLG+ A ++I RL +L +G+SG +L L+
Sbjct 60 GLFSDVRIDPTQYNELQVNLIRSHACGLGEPFSKEVALVMMILRLNTLLKGHSGATLELV 119
Query 132 ERLVWLLNENVIPVIPSEGSVGASGDLTPLSYIAGVLVGEREVYYQGKIIPVQQVYQQKA 191
+L + +NE +IP+IP +GS+GASGDL PLS++A L+GE +V Y+G+ V ++
Sbjct 120 RQLQFFINERIIPIIPQQGSLGASGDLAPLSHLALALIGEGKVLYRGEEKDSDDVLRELN 179
Query 192 IQPLTLRPKEGLALMNGTAVMTAIACLNYKRAEQIAQTATLVTAINVLALEGNPTHFDEV 251
QPL L+ KEGLAL+NGT MTA ++Y AE + + + A+ +L G +
Sbjct 180 RQPLNLQAKEGLALINGTQAMTAQGVISYIEAEDLGYQSEWIAALTHQSLNGIIDAYRHD 239
Query 252 LFAQKPHTGQQKIAAQLRDWLNSEVQTAHQSP-RLQDRYSLRCAPHVIGVFEDSKVWLRQ 310
+ + + Q +AA++RDWL T Q+ R+QD Y+LRC P + G +++Q
Sbjct 240 VHSVRNFQEQINVAARMRDWLEGSTLTTRQAEIRVQDAYTLRCIPQIHGASFQVFNYVKQ 299
Query 311 FIENELNSSNDNPLI--DPVNLRVLHGGHFYGGHIAQAMDSLKIMIANIADLMDRQLAQL 368
+E E+N++NDNPLI + V+ GG+F+G IA A+D LK+ ++ +A++ +R+L +L
Sbjct 300 QLEFEMNAANDNPLIFEEANETFVISGGNFHGQPIAFALDHLKLGVSELANVSERRLERL 359
Query 369 VDHKMNHGLPRNLTGATAERLPLNHGFKAVQIGVSAWTAEALKQTLSASIFSRSTECHNQ 428
V+ ++N LP L+ L G +Q ++ +E AS+ S ++ + +
Sbjct 360 VNPQLNGDLPAFLSPEPG----LQSGAMIMQYAAASLVSENKTLAHPASVDSITSSANQE 415
Query 429 DKVSMGTIAARDATRIIVLTEQVMAALCCASIQAIHLKQLAQQLSPTLR 477
D VSMGT AAR +II +V+A C ++QA LK + + LSP R
Sbjct 416 DHVSMGTTAARHGYQIIENARRVLAIECVIALQAAELKGV-EGLSPKTR 463
>Q6GKT7 Histidine ammonia-lyase [Staphylococcus aureus (strain
MRSA252)]
Length=504
Score = 267 bits (683), Expect = 3e-86
Identities = 164/469 (35%), Positives = 269/469 (57%), Gaps = 10/469 (2%)
Query 12 TLTVGLEPLSIEDVVRVAQAKCRVALPEQQDWRDLIQKGADFLDTLLQEEGVIYGVTTGY 71
TL + E L+IE + Q + ++ + + D + ++K ++ +++ E +YG+TTG+
Sbjct 2 TLYLDGETLTIEYIKSFLQQQSKIEIID--DALERVKKSRAVVERIIENEETVYGITTGF 59
Query 72 GDSCLVEVPTHQVHELPLQLSRFHGCGLGQNLDLVTARAVVITRLCSLARGYSGVSLALL 131
G V + Q +EL + L R H CGLG+ A ++I RL +L +G+SG +L L+
Sbjct 60 GLFSDVRIDPTQYNELQMNLIRSHACGLGEPFSKEVALVMMILRLNTLLKGHSGATLELV 119
Query 132 ERLVWLLNENVIPVIPSEGSVGASGDLTPLSYIAGVLVGEREVYYQGKIIPVQQVYQQKA 191
+L + +NE +IP+IP +GS+GASGDL PLS++A L+GE +V Y+G+ V ++
Sbjct 120 RQLQFFINERIIPIIPQQGSLGASGDLAPLSHLALALIGEGKVLYRGEEKDSDDVLRELN 179
Query 192 IQPLTLRPKEGLALMNGTAVMTAIACLNYKRAEQIAQTATLVTAINVLALEGNPTHFDEV 251
QPL L+ KEGLAL+NGT MTA ++Y AE + + + A+ +L G +
Sbjct 180 RQPLNLQAKEGLALINGTQAMTAQGVISYIEAEDLGYQSEWIAALTHQSLNGIIDAYRHD 239
Query 252 LFAQKPHTGQQKIAAQLRDWLNSEVQTAHQSP-RLQDRYSLRCAPHVIGVFEDSKVWLRQ 310
+ A + Q +AA++RDWL T Q+ R+QD Y+LRC P + G +++Q
Sbjct 240 VHAVRNFQEQINVAARMRDWLEGSTLTTRQAEIRVQDAYTLRCIPQIHGASFQVFNYVKQ 299
Query 311 FIENELNSSNDNPLI-DPVNLR-VLHGGHFYGGHIAQAMDSLKIMIANIADLMDRQLAQL 368
+E E+N++NDNPLI + N V+ GG+F+G IA A+D LK+ ++ +A++ +R+L +L
Sbjct 300 QLEFEMNAANDNPLIFEEANATFVISGGNFHGQPIAFALDHLKLGVSELANVSERRLERL 359
Query 369 VDHKMNHGLPRNLTGATAERLPLNHGFKAVQIGVSAWTAEALKQTLSASIFSRSTECHNQ 428
V+ ++N LP L+ L G +Q ++ +E AS+ S ++ + +
Sbjct 360 VNPQLNGDLPAFLSPEPG----LQSGAMIMQYAAASLVSENKTLAHPASVDSITSSANQE 415
Query 429 DKVSMGTIAARDATRIIVLTEQVMAALCCASIQAIHLKQLAQQLSPTLR 477
D VSMGT AAR +II +V+A C ++QA LK + + LSP R
Sbjct 416 DHVSMGTTAARHGYQIIENARRVLAIECVIALQAAELKGV-EGLSPKTR 463
>A8MF64 Histidine ammonia-lyase [Alkaliphilus oremlandii (strain
OhILAs)]
Length=507
Score = 267 bits (683), Expect = 3e-86
Identities = 162/447 (36%), Positives = 251/447 (56%), Gaps = 8/447 (2%)
Query 18 EPLSIEDVVRVAQAKCRVALPEQQDWRDLIQKGADFLDTLLQEEGVIYGVTTGYGDSCLV 77
E L+++D++ V + + L E D ++ ++ +D ++EE V+YG+TTG+G V
Sbjct 9 EQLTLQDIIHVTRNFYEIELSE--DAKNRVRNNRKVVDRYVEEEKVVYGITTGFGKFSDV 66
Query 78 EVPTHQVHELPLQLSRFHGCGLGQNLDLVTARAVVITRLCSLARGYSGVSLALLERLVWL 137
+ + L L H CG+G L+ R +++ R +L++GYSG+ L L L+ +
Sbjct 67 VISKSETEALQRNLIISHACGVGNPLEEDVVRGIMLLRANALSKGYSGIRLETLSTLIEM 126
Query 138 LNENVIPVIPSEGSVGASGDLTPLSYIAGVLVGEREVYYQGKIIPVQQVYQQKAIQPLTL 197
LN+ V PVIP +GS+GASGDL PLS++ VL+GE E YQGK + ++ + I+P+ L
Sbjct 127 LNKGVHPVIPEKGSLGASGDLAPLSHMVLVLIGEGEAIYQGKRMSGREAMEAAGIRPVVL 186
Query 198 RPKEGLALMNGTAVMTAIACLNYKRAEQIAQTATLVTAINVLALEGNPTHFDEVLFAQKP 257
KEGLAL+NGT VMTAI L A +++ + + A+ + A G T FD+ + +P
Sbjct 187 TSKEGLALINGTQVMTAIGALTVYDAINLSKISDIAAALTIEAQRGIVTAFDKRVHEVRP 246
Query 258 HTGQQKIAAQLRDWLNSEVQTAHQSP-RLQDRYSLRCAPHVIGVFEDSKVWLRQFIENEL 316
H GQ A L L T Q ++QD Y+LRC P + G +D+ ++ I E+
Sbjct 247 HAGQISCAENLNRLLEGSTYTTKQGEIKVQDAYTLRCIPQIHGASKDAIQYVENKINIEI 306
Query 317 NSSNDNPLIDPVNLRVLHGGHFYGGHIAQAMDSLKIMIANIADLMDRQLAQLVDHKMNHG 376
NS+ DNPLI + V+ GG+F+G +A + D L I +A IA++ +R++ +LV+ +++ G
Sbjct 307 NSATDNPLIFSEDNDVISGGNFHGQPMALSFDFLGIALAEIANVSERRIERLVNPQLS-G 365
Query 377 LPRNLTGATAERLPLNHGFKAVQIGVSAWTAEALKQTLSASIFSRSTECHNQDKVSMGTI 436
LP LT E+ LN GF Q +A +E AS+ S + + +D VSMGTI
Sbjct 366 LPAFLT----EKGGLNSGFMITQYSAAALVSENKVLAHPASVDSIPSSANQEDHVSMGTI 421
Query 437 AARDATRIIVLTEQVMAALCCASIQAI 463
AAR A I V+A A+ Q I
Sbjct 422 AARKAREIYKNAVNVVAIELMAAAQGI 448
>A7ZAE4 Histidine ammonia-lyase [Bacillus velezensis (strain DSM
23117 / BGSC 10A6 / LMG 26770 / FZB42)]
Length=512
Score = 263 bits (673), Expect = 1e-84
Identities = 154/466 (33%), Positives = 263/466 (56%), Gaps = 19/466 (4%)
Query 47 IQKGADFLDTLLQEEGVIYGVTTGYGDSCLVEVPTHQVHELPLQLSRFHGCGLGQNLDLV 106
++K ++ ++QEE IYG+TTG+G V + +L L L H CG+G
Sbjct 34 VKKSRAAVERIVQEEKTIYGITTGFGKFSDVLIQKEDAADLQLNLILSHACGVGDPFPES 93
Query 107 TARAVVITRLCSLARGYSGVSLALLERLVWLLNENVIPVIPSEGSVGASGDLTPLSYIAG 166
+RA+++ R +L +G+SGV L+++L+ LN + PVIP +GS+GASGDL PLS++A
Sbjct 94 VSRAMLLLRANALLKGFSGVRTELIDQLLAYLNHRIHPVIPQQGSLGASGDLAPLSHLAL 153
Query 167 VLVGEREVYYQGKIIPVQQVYQQKAIQPLTLRPKEGLALMNGTAVMTAIACLNYKRAEQI 226
L+G+ EV+Y+G +P +Q +QP L KEGLAL+NGT MTA+ + Y AE++
Sbjct 154 ALIGQGEVFYEGARMPTAHALEQTNLQPAVLTSKEGLALINGTQAMTAMGLIAYLEAEKL 213
Query 227 AQTATLVTAINVLALEGNPTHFDEVLFAQKPHTGQQKIAAQLRDWL-NSEVQTAHQSPRL 285
A + + ++ + L+G FDE + A + + Q +A ++R +L +S++ T R+
Sbjct 214 AYQSERIASLTIEGLQGIIDAFDEDIHAARGYQEQMDVAERIRYYLSDSKLTTVQGELRV 273
Query 286 QDRYSLRCAPHVIGVFEDSKVWLRQFIENELNSSNDNPLIDPVNLRVLHGGHFYGGHIAQ 345
QD YS+RC P V G + ++++ +E E+N++ DNPLI +++ GG+F+G IA
Sbjct 274 QDAYSIRCIPQVHGASWQTLAYVKEKLEIEMNAATDNPLIFEDGAKIISGGNFHGQPIAF 333
Query 346 AMDSLKIMIANIADLMDRQLAQLVDHKMNHGLPRNLTGATAERLPLNHGFKAVQIGVSAW 405
AMD LK+ A +A++ +R++ +LV+ ++N +L + + L G +Q ++
Sbjct 334 AMDFLKVAAAELANISERRIERLVNPQLN-----DLPPFLSPQPGLQSGAMIMQYAAASL 388
Query 406 TAEALKQTLSASIFSRSTECHNQDKVSMGTIAARDATRIIVLTEQVMAALCCASIQAI-- 463
+E AS+ S + + +D VSMGTIA+R A +II T +V+A ++QA+
Sbjct 389 VSENKTLAHPASVDSIPSSANQEDHVSMGTIASRHAYQIIANTRRVLAVEAICALQAVEY 448
Query 464 ----HLKQLAQQLSPTLRAFSAWTLHSLALVIEDRPLQTELQQIVD 505
H +QL +R + + + EDR +++ + D
Sbjct 449 RGEEHCASYTKQLYHEMR-------NIVPSIQEDRVFSYDIEHLSD 487
>P42357 Histidine ammonia-lyase [Homo sapiens]
Length=657
Score = 266 bits (681), Expect = 2e-84
Identities = 158/467 (34%), Positives = 268/467 (57%), Gaps = 14/467 (3%)
Query 20 LSIEDVVRVAQAKCRVALPEQQDWRDLIQKGADFLDTLLQEEGVIYGVTTGYGDSCLVEV 79
L+ ED+V + + + ++ L + R +QK + +D++++E+ V+YG+TTG+G +
Sbjct 121 LTTEDLVNLGKGRYKIKLTPTAEKR--VQKSREVIDSIIKEKTVVYGITTGFGKFARTVI 178
Query 80 PTHQVHELPLQLSRFHGCGLGQNLDLVTARAVVITRLCSLARGYSGVSLALLERLVWLLN 139
P +++ EL + L R H G+G+ L R ++ R+ LA+GYSG+SL L++++ + N
Sbjct 179 PINKLQELQVNLVRSHSSGVGKPLSPERCRMLLALRINVLAKGYSGISLETLKQVIEMFN 238
Query 140 ENVIPVIPSEGSVGASGDLTPLSYIAGVLVGEREVYY-QGKIIPVQQVYQQKAIQPLTLR 198
+ +P +P +G+VGASGDL PLS++A LVGE +++ + + V + ++P+ L+
Sbjct 239 ASCLPYVPEKGTVGASGDLAPLSHLALGLVGEGKMWSPKSGWADAKYVLEAHGLKPVILK 298
Query 199 PKEGLALMNGTAVMTAIACLNYKRAEQIAQTATLVTAINVLALEGNPTHFDEVLFAQKPH 258
PKEGLAL+NGT ++T++ C +RA IA+ A +V A+ + L+G FD + A +PH
Sbjct 299 PKEGLALINGTQMITSLGCEAVERASAIARQADIVAALTLEVLKGTTKAFDTDIHALRPH 358
Query 259 TGQQKIAAQLRDWLN-----SEVQTAHQ-SPRLQDRYSLRCAPHVIGVFEDSKVWLRQFI 312
GQ ++A + R L+ SE+ +H+ R+QD Y+LRC P V GV D+ +++ I
Sbjct 359 RGQIEVAFRFRSLLDSDHHPSEIAESHRFCDRVQDAYTLRCCPQVHGVVNDTIAFVKNII 418
Query 313 ENELNSSNDNPLIDPVNLRVLHGGHFYGGHIAQAMDSLKIMIANIADLMDRQLAQLVDHK 372
ELNS+ DNP++ + GG+F+G + A+A+D L I I +A + +R++ +L +
Sbjct 419 TTELNSATDNPMVFANRGETVSGGNFHGEYPAKALDYLAIGIHELAAISERRIERLCNPS 478
Query 373 MNHGLPRNLTGATAERLPLNHGFKAVQIGVSAWTAEALKQTLSASIFSRSTECHNQDKVS 432
++ LP L LN GF +A +E +S+ S ST +D VS
Sbjct 479 LSE-LPAFLVAEGG----LNSGFMIAHCTAAALVSENKALCHPSSVDSLSTSAATEDHVS 533
Query 433 MGTIAARDATRIIVLTEQVMAALCCASIQAIHLKQLAQQLSPTLRAF 479
MG AAR A R+I EQV+A A+ Q I + + +P + +
Sbjct 534 MGGWAARKALRVIEHVEQVLAIELLAACQGIEFLRPLKTTTPLEKVY 580
>P10944 Histidine ammonia-lyase [Bacillus subtilis (strain 168)]
Length=508
Score = 260 bits (665), Expect = 1e-83
Identities = 167/511 (33%), Positives = 282/511 (55%), Gaps = 22/511 (4%)
Query 13 LTVGLEPLSIEDVVRVAQAKCRVALPEQQDWRDLIQKGADFLDTLLQEEGVIYGVTTGYG 72
+T+ L+ DV RV A E+ R ++K ++ ++++E IYG+ TG+G
Sbjct 2 VTLDGSSLTTADVARVLFDFEEAAASEESMER--VKKSRAAVERIVRDEKTIYGINTGFG 59
Query 73 DSCLVEVPTHQVHELPLQLSRFHGCGLGQNLDLVTARAVVITRLCSLARGYSGVSLALLE 132
V + L L L H CG+G +RA+++ R +L +G+SGV L+E
Sbjct 60 KFSDVLIQKEDSAALQLNLILSHACGVGDPFPECVSRAMLLLRANALLKGFSGVRAELIE 119
Query 133 RLVWLLNENVIPVIPSEGSVGASGDLTPLSYIAGVLVGEREVYYQGKIIPVQQVYQQKAI 192
+L+ LN+ V PVIP +GS+GASGDL PLS++A L+G+ EV+++G+ +P ++ I
Sbjct 120 QLLAFLNKRVHPVIPQQGSLGASGDLAPLSHLALALIGQGEVFFEGERMPAMTGLKKAGI 179
Query 193 QPLTLRPKEGLALMNGTAVMTAIACLNYKRAEQIAQTATLVTAINVLALEGNPTHFDEVL 252
QP+TL KEGLAL+NGT MTA+ + Y AE++A + ++ + L+G FDE +
Sbjct 180 QPVTLTSKEGLALINGTQAMTAMGVVAYIEAEKLAYQTERIASLTIEGLQGIIDAFDEDI 239
Query 253 FAQKPHTGQQKIAAQLRDWL-NSEVQTAHQSPRLQDRYSLRCAPHVIGVFEDSKVWLRQF 311
+ + Q +A ++R +L +S + T+ R+QD YSLRC P V G + ++++
Sbjct 240 HLARGYQEQIDVAERIRFYLSDSGLTTSQGELRVQDAYSLRCIPQVHGATWQTLGYVKEK 299
Query 312 IENELNSSNDNPLIDPVNLRVLHGGHFYGGHIAQAMDSLKIMIANIADLMDRQLAQLVDH 371
+E E+N++ DNPLI +V+ GG+F+G IA AMD LKI I+ +A++ +R++ +LV+
Sbjct 300 LEIEMNAATDNPLIFNDGDKVISGGNFHGQPIAFAMDFLKIAISELANIAERRIERLVNP 359
Query 372 KMNHGLPRNLTGATAERLPLNHGFKAVQIGVSAWTAEALKQTLSASIFSRSTECHNQDKV 431
++N +L + L G +Q ++ +E AS+ S + + +D V
Sbjct 360 QLN-----DLPPFLSPHPGLQSGAMIMQYAAASLVSENKTLAHPASVDSIPSSANQEDHV 414
Query 432 SMGTIAARDATRIIVLTEQVMAALCCASIQAIHLKQLAQQLSPTLRAFSAWTLHSLALVI 491
SMGTIAAR A ++I T +V+A ++QA+ + + S T + F
Sbjct 415 SMGTIAARHAYQVIANTRRVIAIEAICALQAVEYRGIEHAASYTKQLFQ----------- 463
Query 492 EDRPLQTELQQIVDRFAHFELSN-ADWMQQQ 521
E R + +QQ DR +++ DW++++
Sbjct 464 EMRKVVPSIQQ--DRVFSYDIERLTDWLKKE 492
>Q20502 Histidine ammonia-lyase [Caenorhabditis elegans]
Length=677
Score = 264 bits (674), Expect = 3e-83
Identities = 163/491 (33%), Positives = 279/491 (57%), Gaps = 17/491 (3%)
Query 23 EDVVRVAQAKCRVALPEQQDWRDLIQKGADFLDTLLQEEGVIYGVTTGYGDSCLVEVPTH 82
ED+VR + +C + L + + D I+K FL+ + E +YGVTTG+G V +P
Sbjct 140 EDLVRCEKGECAIQLSMESE--DRIRKARTFLEKIASEHRAVYGVTTGFGTFSNVTIPPE 197
Query 83 QVHELPLQLSRFHGCGLGQNLDLVTARAVVITRLCSLARGYSGVSLALLERLVWLLNENV 142
++ +L L L R H G G+ L AR ++ R+ LA+G+SG+S+ +++++ N
Sbjct 198 KLKKLQLNLIRSHATGYGEPLAPNRARMLLALRINILAKGHSGISVENIKKMIAAFNAFC 257
Query 143 IPVIPSEGSVGASGDLTPLSYIAGVLVGEREVYYQGK-IIPVQQVYQQKAIQPLTLRPKE 201
+ +P +G+VG SGDL PL+++A L+GE +++ P V ++ ++PL L PKE
Sbjct 258 VSYVPQQGTVGCSGDLCPLAHLALGLLGEGKMWSPTTGWQPADVVLKKNNLEPLELGPKE 317
Query 202 GLALMNGTAVMTAIACLNYKRAEQIAQTATLVTAINVLALEGNPTHFDEVLFAQKPHTGQ 261
GLAL+NGT ++TA+ +RA IA+ A ++ A+++ L+G +D + +PH GQ
Sbjct 318 GLALINGTQMVTALGAYTLERAHNIARQADVIAALSLDVLKGTTRAYDPDIHRIRPHRGQ 377
Query 262 QKIAAQLRDWLNSE-----VQTAHQS-PRLQDRYSLRCAPHVIGVFEDSKVWLRQFIENE 315
A +LR L+SE + +H++ ++QD Y+LRC P V GV D+ ++R+ I E
Sbjct 378 NLSALRLRALLHSEANPSQIAESHRNCTKVQDAYTLRCVPQVHGVVHDTIEFVREIITTE 437
Query 316 LNSSNDNPLIDPVNLRVLHGGHFYGGHIAQAMDSLKIMIANIADLMDRQLAQLVDHKMNH 375
+NS+ DNPL+ ++ GG+F+G + A+A+D L I +A +A + +R+L +LV+ +++
Sbjct 438 MNSATDNPLVFADREEIISGGNFHGEYPAKALDFLAIAVAELAQMSERRLERLVNKELS- 496
Query 376 GLPRNLTGATAERLPLNHGFKAVQIGVSAWTAEALKQTLSASIFSRSTECHNQDKVSMGT 435
GLP LT LN GF VQ+ ++ +E +S+ S T C+ +D VSMG
Sbjct 497 GLPTFLTPDGG----LNSGFMTVQLCAASLVSENKVLCHPSSVDSIPTSCNQEDHVSMGG 552
Query 436 IAARDATRIIVLTEQVMAALCCASIQAIHLKQLAQQLSPTLRAFSAWTLHSLALVI-EDR 494
AAR A ++ E V+A A+ Q I + +P + + + S+A + EDR
Sbjct 553 FAARKALTVVEHVEAVLAMELLAACQGIEFLKPLISTAPLHKIYQ--LVRSVAPPLNEDR 610
Query 495 PLQTELQQIVD 505
++ E+ +++
Sbjct 611 YMKPEIDAVLE 621
>Q8GMG0 MIO-dependent tyrosine 2,3-aminomutase [Streptomyces globisporus]
Length=539
Score = 259 bits (663), Expect = 6e-83
Identities = 184/535 (34%), Positives = 279/535 (52%), Gaps = 34/535 (6%)
Query 7 ITQPQT----LTVGLEPLSIEDVVRVAQAKCRVALPEQQDWRDLIQKGADFLDTLLQEEG 62
+TQ +T ++V E L++E V RVA+ + V +P + + QK + + + ++
Sbjct 3 LTQVETEIVPVSVDGETLTVEAVRRVAEERATVDVPAESIAK--AQKSREIFEGIAEQNI 60
Query 63 VIYGVTTGYGDSCLVEVPTHQVHELPLQLSRFHGCGLGQNLDLVTARAVVITRLCSLARG 122
IYGVTTGYG+ ++V + EL L R H G+G ARA+V RL +LA+G
Sbjct 61 PIYGVTTGYGEMIYMQVDKSKEVELQTNLVRSHSAGVGPLFAEDEARAIVAARLNTLAKG 120
Query 123 YSGVSLALLERLVWLLNENVIPVIPSEGSVGASGDLTPLSYIAGVLVGEREVYYQGKIIP 182
+S V +LERL LNE + P IP GS+GASGDL PLS++A L+GE V G+ +
Sbjct 121 HSAVRPIILERLAQYLNEGITPAIPEIGSLGASGDLAPLSHVASTLIGEGYVLRDGRPVE 180
Query 183 VQQVYQQKAIQPLTLRPKEGLALMNGTAVMTAIACLNYKRAEQIAQTATLVTAINVLALE 242
QV ++ I+PL LR KEGLAL+NGT+ MT + L RA + AQ A +VTA+ + A+
Sbjct 181 TAQVLAERGIEPLELRFKEGLALINGTSGMTGLGSLVVGRALEQAQQAEIVTALLIEAVR 240
Query 243 GNPTHF-DEVLFAQKPHTGQQKIAAQLRDW------------LNSEVQTAHQSPR----- 284
G+ + F E +PH GQ AA +R L E+Q ++ +
Sbjct 241 GSTSPFLAEGHDIARPHEGQIDTAANMRALMRGSGLTVEHADLRRELQKDKEAGKDVQRS 300
Query 285 ---LQDRYSLRCAPHVIGVFEDSKVWLRQFIENELNSSNDNPLIDPVNLRVLHGGHFYGG 341
LQ YSLR P V+G D+ R + ELNS+NDNPL + HG +F+G
Sbjct 301 EIYLQKAYSLRAIPQVVGAVRDTLYHARHKLRIELNSANDNPLFFE-GKEIFHGANFHGQ 359
Query 342 HIAQAMDSLKIMIANIADLMDRQLAQLVDHKMNHGLPRNLTGATAERLPLNHGFKAVQIG 401
IA AMD + I + + L +RQ+ ++++ +++GLP L L+ GF Q
Sbjct 360 PIAFAMDFVTIALTQLGVLAERQINRVLNRHLSYGLPEFLVSGDP---GLHSGFAGAQYP 416
Query 402 VSAWTAEALKQTLS-ASIFSRSTECHNQDKVSMGTIAARDATRIIVLTEQVMAALCCASI 460
+A AE +T+ AS S + NQD VSMG I+AR+A R++ +++A A+
Sbjct 417 ATALVAE--NRTIGPASTQSVPSNGDNQDVVSMGLISARNARRVLSNNNKILAVEYLAAA 474
Query 461 QAIHLKQLAQQLSPTLRAFSAWTLHSLALVIEDRPLQTELQQIVDRFAHFELSNA 515
QA+ + LSP +A + + DR + +++ + D + E A
Sbjct 475 QAVDISGRFDGLSPAAKATYEAVRRLVPTLGVDRYMADDIELVADALSRGEFLRA 529
>P35492 Histidine ammonia-lyase [Mus musculus]
Length=657
Score = 262 bits (670), Expect = 9e-83
Identities = 153/469 (33%), Positives = 267/469 (57%), Gaps = 14/469 (3%)
Query 18 EPLSIEDVVRVAQAKCRVALPEQQDWRDLIQKGADFLDTLLQEEGVIYGVTTGYGDSCLV 77
+ LS ED+V + + + ++ L + + +Q+ + +D++++E V+YG+TTG+G
Sbjct 119 DSLSTEDLVNLGKGRYKIKLTSIAEKK--VQQSREVIDSIIKERTVVYGITTGFGKFART 176
Query 78 EVPTHQVHELPLQLSRFHGCGLGQNLDLVTARAVVITRLCSLARGYSGVSLALLERLVWL 137
+P +++ EL + L R H G+G+ L R ++ R+ LA+GYSG+SL L++++
Sbjct 177 VIPANKLQELQVNLVRSHSSGVGKPLSPERCRMLLALRINVLAKGYSGISLETLKQVIEA 236
Query 138 LNENVIPVIPSEGSVGASGDLTPLSYIAGVLVGEREVYY-QGKIIPVQQVYQQKAIQPLT 196
N + + +P +G+VGASGDL PLS++A L+GE +++ + + V + ++P+
Sbjct 237 FNASCLSYVPEKGTVGASGDLAPLSHLALGLIGEGKMWSPKSGWADAKYVLEAHGLKPIV 296
Query 197 LRPKEGLALMNGTAVMTAIACLNYKRAEQIAQTATLVTAINVLALEGNPTHFDEVLFAQK 256
L+PKEGLAL+NGT ++T++ C +RA IA+ A +V A+ + L+G FD + A +
Sbjct 297 LKPKEGLALINGTQMITSLGCEALERASAIARQADIVAALTLEVLKGTTKAFDTDIHAVR 356
Query 257 PHTGQQKIAAQLRDWLN-----SEVQTAHQ-SPRLQDRYSLRCAPHVIGVFEDSKVWLRQ 310
PH GQ ++A + R L+ SE+ +H+ R+QD Y+LRC P V GV D+ +++
Sbjct 357 PHRGQIEVAFRFRSLLDSDHHPSEIAESHRFCDRVQDAYTLRCCPQVHGVVNDTIAFVKD 416
Query 311 FIENELNSSNDNPLIDPVNLRVLHGGHFYGGHIAQAMDSLKIMIANIADLMDRQLAQLVD 370
I ELNS+ DNP++ + GG+F+G + A+A+D L I + +A + +R++ +L +
Sbjct 417 IITTELNSATDNPMVFASRGETISGGNFHGEYPAKALDYLAIGVHELAAISERRIERLCN 476
Query 371 HKMNHGLPRNLTGATAERLPLNHGFKAVQIGVSAWTAEALKQTLSASIFSRSTECHNQDK 430
++ LP L LN GF +A +E+ +S+ S ST +D
Sbjct 477 PSLSE-LPAFLVAEGG----LNSGFMIAHCTAAALVSESKALCHPSSVDSLSTSAATEDH 531
Query 431 VSMGTIAARDATRIIVLTEQVMAALCCASIQAIHLKQLAQQLSPTLRAF 479
VSMG AAR A R++ EQV+A A+ Q I + + +P + +
Sbjct 532 VSMGGWAARKALRVVEHVEQVLAIELLAACQGIEFLRPLKTTTPLEKVY 580
>P21213 Histidine ammonia-lyase [Rattus norvegicus]
Length=657
Score = 262 bits (670), Expect = 9e-83
Identities = 154/469 (33%), Positives = 267/469 (57%), Gaps = 14/469 (3%)
Query 18 EPLSIEDVVRVAQAKCRVALPEQQDWRDLIQKGADFLDTLLQEEGVIYGVTTGYGDSCLV 77
+ LS ED+V + + ++ L + + +Q+ + +D++++E V+YG+TTG+G
Sbjct 119 DSLSTEDLVNLGKGHYKIKLTSIAEKK--VQQSREVIDSIIKERTVVYGITTGFGKFART 176
Query 78 EVPTHQVHELPLQLSRFHGCGLGQNLDLVTARAVVITRLCSLARGYSGVSLALLERLVWL 137
+P +++ EL + L R H G+G+ L R ++ R+ LA+GYSG+SL L++++ +
Sbjct 177 VIPANKLQELQVNLVRSHSSGVGKPLSPERCRMLLALRINVLAKGYSGISLETLKQVIEV 236
Query 138 LNENVIPVIPSEGSVGASGDLTPLSYIAGVLVGEREVYY-QGKIIPVQQVYQQKAIQPLT 196
N + + +P +G+VGASGDL PLS++A L+GE +++ + + V + ++P+
Sbjct 237 FNASCLSYVPEKGTVGASGDLAPLSHLALGLIGEGKMWSPKSGWADAKYVLEAHGLKPIV 296
Query 197 LRPKEGLALMNGTAVMTAIACLNYKRAEQIAQTATLVTAINVLALEGNPTHFDEVLFAQK 256
L+PKEGLAL+NGT ++T++ C +RA IA+ A +V A+ + L+G FD + A +
Sbjct 297 LKPKEGLALINGTQMITSLGCEAVERASAIARQADIVAALTLEVLKGTTKAFDTDIHAVR 356
Query 257 PHTGQQKIAAQLRDWLN-----SEVQTAHQ-SPRLQDRYSLRCAPHVIGVFEDSKVWLRQ 310
PH GQ ++A + R L+ SE+ +H+ R+QD Y+LRC P V GV D+ +++
Sbjct 357 PHRGQIEVAFRFRSLLDSDHHPSEIAESHRFCDRVQDAYTLRCCPQVHGVVNDTIAFVKD 416
Query 311 FIENELNSSNDNPLIDPVNLRVLHGGHFYGGHIAQAMDSLKIMIANIADLMDRQLAQLVD 370
I ELNS+ DNP++ + GG+F+G + A+A+D L I + +A + +R++ +L +
Sbjct 417 IITTELNSATDNPMVFASRGETISGGNFHGEYPAKALDYLAIGVHELAAISERRIERLCN 476
Query 371 HKMNHGLPRNLTGATAERLPLNHGFKAVQIGVSAWTAEALKQTLSASIFSRSTECHNQDK 430
++ LP L LN GF +A +E+ +S+ S ST +D
Sbjct 477 PSLSE-LPAFLVAEGG----LNSGFMIAHCTAAALVSESKALCHPSSVDSLSTSAATEDH 531
Query 431 VSMGTIAARDATRIIVLTEQVMAALCCASIQAIHLKQLAQQLSPTLRAF 479
VSMG AAR A R+I EQV+A A+ Q I + + +P + +
Sbjct 532 VSMGGWAARKALRVIEHVEQVLAIELLAACQGIEFLRPLKTTTPLEKVY 580
Score = 20.0 bits (40), Expect = 6.2
Identities = 29/126 (23%), Positives = 51/126 (40%), Gaps = 15/126 (12%)
Query 16 GLEPLSIEDVVRVAQAKCRVALPEQQDWRDLIQKGADF-----LDTLLQEEGVIYGVTTG 70
G+ +++ V+ V A C +PE + + D L L EG ++ +G
Sbjct 224 GISLETLKQVIEVFNASCLSYVPE----KGTVGASGDLAPLSHLALGLIGEGKMWSPKSG 279
Query 71 YGDSCLVEVPTHQVHEL-PLQLSRFHGCGLGQNLDLVTARAV-VITRLCSLARGYSGVSL 128
+ D+ V + H L P+ L G L ++T+ + R ++AR V+
Sbjct 280 WADAKYV----LEAHGLKPIVLKPKEGLALINGTQMITSLGCEAVERASAIARQADIVAA 335
Query 129 ALLERL 134
LE L
Sbjct 336 LTLEVL 341
>Q0VZ68 Tyrosine 2,3-aminomutase [Chondromyces crocatus]
Length=531
Score = 250 bits (638), Expect = 2e-79
Identities = 178/508 (35%), Positives = 260/508 (51%), Gaps = 27/508 (5%)
Query 20 LSIEDVVRVAQAKCRVALPEQQDWRDLIQKGADFLDTLLQEEGVIYGVTTGYGDSCLVEV 79
LSI DV V + V L Q R + + + + IYGV TG+G+ V +
Sbjct 8 LSIYDVADVCMKRATVELDPSQLER--VAVAHERTQAWGEAQHPIYGVNTGFGELVPVMI 65
Query 80 PTHQVHELPLQLSRFHGCGLGQNLDLVTARAVVITRLCSLARGYSGVSLALLERLVWLLN 139
P EL L R H G G+ RA+++ RL L +GYSG S+ ++ L +N
Sbjct 66 PRQHKRELQENLIRSHAAGGGEPFADDVVRAIMLARLNCLMKGYSGASVETVKLLAEFIN 125
Query 140 ENVIPVIPSEGSVGASGDLTPLSYIAGVLVGEREVYYQGKIIPVQQVYQQKAIQPLTLRP 199
+ PVIP +GS+GASGDL+PLS+IA L+GE V ++G++ V +++ ++PL L
Sbjct 126 RGIHPVIPQQGSLGASGDLSPLSHIALALIGEGTVSFKGQVRKTGDVLREEGLKPLELGF 185
Query 200 KEGLALMNGTAVMTAIACLNYKRAEQIAQTATLVTAINVLALEGNPTHFDEVLFAQKPHT 259
K GL L+NGT+ MT AC+ RA + + A L TA V L G+ F+E K H+
Sbjct 186 KGGLTLINGTSAMTGAACVALGRAYHLFRLALLATADFVQCLGGSTGPFEERGHLPKNHS 245
Query 260 GQQKIAAQLRDWL-NSEVQTAHQ-------------------SPRLQDRYSLRCAPHVIG 299
GQ +A ++R L S++ + HQ LQD Y+LR P ++G
Sbjct 246 GQVIVAREIRKLLAGSQLTSDHQDLMKEMVARSGVGNDVVDTGVYLQDAYTLRAVPQILG 305
Query 300 VFEDSKVWLRQFIENELNSSNDNPLIDPVNLRVLHGGHFYGGHIAQAMDSLKIMIANIAD 359
D+ + R+ IE ELNS+NDNPLI V + HG +F+G ++A A D L I + I
Sbjct 306 PVLDTLDFARKLIEEELNSTNDNPLIFDVPEQTFHGANFHGQYVAMACDYLNIAVTEIGV 365
Query 360 LMDRQLAQLVDHKMNHGLPRNLTGATAERLPLNHGFKAVQIGVSAWTAEALKQTLSASIF 419
L +RQL +LVD +N LP L A + L GF+ Q ++ +E L +SI
Sbjct 366 LAERQLNRLVDPNINGKLPPFLASAHSGLL---CGFEGGQYLATSIASENLDLAAPSSIK 422
Query 420 SRSTECHNQDKVSMGTIAARDATRIIVLTEQVMAALCCASIQAIHLKQLAQQLSPTLRAF 479
S + NQD VSMGT +AR + R+ +++ L A QA H+ ++ SP +R
Sbjct 423 SLPSNGSNQDVVSMGTTSARKSLRLCENVGTIVSTLIAACNQAGHILG-NERFSPPIREL 481
Query 480 SAWTLHSLALVIEDRPLQTELQQIVDRF 507
S+ L +D P+ EL Q V F
Sbjct 482 HGELSRSVPLYQDDSPI-FELFQTVRAF 508
>Q93TX3 Histidine ammonia-lyase [Stigmatella aurantiaca]
Length=510
Score = 244 bits (624), Expect = 2e-77
Identities = 151/457 (33%), Positives = 247/457 (54%), Gaps = 9/457 (2%)
Query 13 LTVGLEPLSIEDVVRVAQAKCRVALPEQQDWRDLIQKGADFLDTLLQEEGVIYGVTTGYG 72
L + + L +E++++VA+ V L R ++ D +D + + YG+ TG+G
Sbjct 6 LNIDGDTLKLEEILQVARHTVTVELAPAAAAR--VKAARDLVDRVAAGDTPSYGINTGFG 63
Query 73 DSCLVEVPTHQVHELPLQLSRFHGCGLGQNLDLVTARAVVITRLCSLARGYSGVSLALLE 132
V + + EL L H G+G L L AR +++ R LA+GYSG+ L
Sbjct 64 TLAEVRIDKKDLRELQRNLILSHAAGVGSPLPLPEARVLLLLRCNVLAKGYSGIRPETLA 123
Query 133 RLVWLLNENVIPVIPSEGSVGASGDLTPLSYIAGVLVGEREVYYQGKIIPVQQVYQQKAI 192
+ +LN +V+PV+P GSVGASGDL PL+++A V +GE E +Y+G+ +P Q ++ +
Sbjct 124 LALEMLNRDVVPVVPERGSVGASGDLAPLAHLALVFIGEGEAFYKGERLPAAQALERAGL 183
Query 193 QPLTLRPKEGLALMNGTAVMTAIACLNYKRAEQIAQTATLVTAINVLALEGNPTHFDEVL 252
+P+ L KEGLAL+NGT M A+ L RAE +A A L A+ + L G+ F +
Sbjct 184 KPVVLEAKEGLALVNGTQAMCAVGTLLQLRAEMLADLADLAGAMTLEGLLGSHKPFIPEI 243
Query 253 FAQKPHTGQQKIAAQLRDWL--NSEVQTAHQSPRLQDRYSLRCAPHVIGVFEDSKVWLRQ 310
+ H GQ+ AA LR+ L ++ V++ ++QD YSLRC P V G + + R+
Sbjct 244 QDVRAHEGQKACAAHLRELLADSALVESHVNCSKVQDPYSLRCMPQVHGAAREGLSFARR 303
Query 311 FIENELNSSNDNPLIDPVNLRVLHGGHFYGGHIAQAMDSLKIMIANIADLMDRQLAQLVD 370
+E E+NS+ DNPL+ R++ GG+F+G ++ A+D + + ++ + +R++ QLV+
Sbjct 304 ILEVEINSATDNPLVFVETERIVSGGNFHGQPVSLALDVAAMALTQLSAISERRVEQLVN 363
Query 371 HKMNHGLPRNLTGATAERLPLNHGFKAVQIGVSAWTAEALKQTLSASIFSRSTECHNQDK 430
++ GLP L A+ LN GF Q+ +A AE+ + AS+ S + +D
Sbjct 364 PALS-GLPPFL----AKNSGLNSGFMIAQVTSAALVAESRVLSHPASVDSIPSSAGREDH 418
Query 431 VSMGTIAARDATRIIVLTEQVMAALCCASIQAIHLKQ 467
VSMG AA ++ T +A + QA+ +Q
Sbjct 419 VSMGMTAALKGRQVADFTRSCLAIELLVAAQALDYRQ 455
>Q3M5Z3 Phenylalanine ammonia-lyase [Trichormus variabilis (strain
ATCC 29413 / PCC 7937)]
Length=567
Score = 239 bits (611), Expect = 5e-75
Identities = 165/465 (35%), Positives = 230/465 (49%), Gaps = 15/465 (3%)
Query 15 VGLEPLSIEDVVRVAQAKCRVALPEQQDWRDLIQKGADFLDTLLQEEGVIYGVTTGYGDS 74
+G + L+I DV RVA+ V+L D IQ D+++ ++ IYGVT+G+G
Sbjct 28 IGNQKLTINDVARVARNGTLVSLTNNTDILQGIQASCDYINNAVESGEPIYGVTSGFGGM 87
Query 75 CLVEVPTHQVHELPLQLSRFHGCGLGQNLDLVTARAVVITRLCSLARGYSGVSLALLERL 134
V + Q EL L F G G L L RA ++ R S RG SG+ L L++R+
Sbjct 88 ANVAISREQASELQTNLVWFLKTGAGNKLPLADVRAAMLLRANSHMRGASGIRLELIKRM 147
Query 135 VWLLNENVIPVIPSEGSVGASGDLTPLSYIAGVLVG---EREVYYQGKIIPVQQVYQQKA 191
LN V P + GS+GASGDL PLSYI G L+G +V + GK + +Q
Sbjct 148 EIFLNAGVTPYVYEFGSIGASGDLVPLSYITGSLIGLDPSFKVDFNGKEMDAPTALRQLN 207
Query 192 IQPLTLRPKEGLALMNGTAVMTAIACLNYKRAEQIAQTATLVTAINVLALEGNPTHFDEV 251
+ PLTL PKEGLA+MNGT+VMT IA + + A V A+++ AL G F
Sbjct 208 LSPLTLLPKEGLAMMNGTSVMTGIAANCVYDTQILTAIAMGVHALDIQALNGTNQSFHPF 267
Query 252 LFAQKPHTGQQKIAAQLRDWL------NSEVQTAH---QSPRLQDRYSLRCAPHVIGVFE 302
+ KPH GQ A Q+ L E+ H +QDRYSLRC P +G
Sbjct 268 IHNSKPHPGQLWAADQMISLLANSQLVRDELDGKHDYRDHELIQDRYSLRCLPQYLGPIV 327
Query 303 DSKVWLRQFIENELNSSNDNPLIDPVNLRVLHGGHFYGGHIAQAMDSLKIMIANIADLMD 362
D + + IE E+NS DNPLID N HGG+F G ++ MD L+ I +A +D
Sbjct 328 DGISQIAKQIEIEINSVTDNPLIDVDNQASYHGGNFLGQYVGMGMDHLRYYIGLLAKHLD 387
Query 363 RQLAQLVDHKMNHGLPRNLTGATAERLPLNHGFKAVQI-GVSAWTAEALKQTLSASIFSR 421
Q+A L + ++GLP +L G + +N G K +QI G S A F
Sbjct 388 VQIALLASPEFSNGLPPSLLGNRERK--VNMGLKGLQICGNSIMPLLTFYGNSIADRFPT 445
Query 422 STECHNQDKVSMGTIAARDATRIIVLTEQVMAALCCASIQAIHLK 466
E NQ+ S G +A A R + + + +A +QA+ L+
Sbjct 446 HAEQFNQNINSQGYTSATLARRSVDIFQNYVAIALMFGVQAVDLR 490
>Q3IWB0 Tyrosine ammonia-lyase [Cereibacter sphaeroides (strain
ATCC 17023 / DSM 158 / JCM 6121 / CCUG 31486 / LMG 2827 /
NBRC 12203 / NCIMB 8253 / ATH 2.4.1.)]
Length=523
Score = 238 bits (606), Expect = 9e-75
Identities = 169/500 (34%), Positives = 247/500 (49%), Gaps = 25/500 (5%)
Query 20 LSIEDVVRVAQAKCRVALPEQQDWRDLIQKGADFLDTLLQEEGVIYGVTTGYGDSCLVEV 79
+ ++ VA R+ L RD + L +++E +YG+TTG+G +
Sbjct 17 IDLDQAHAVASGGARIVLAPPA--RDRCRASEARLGAVIREARHVYGLTTGFGPLANRLI 74
Query 80 PTHQVHELPLQLSRFHGCGLGQNLDLVTARAVVITRLCSLARGYSGVSLALLERLVWLLN 139
V L L G+G LD TARA+V+ RL S+A+G SG S + RL+ LLN
Sbjct 75 SGENVRTLQANLVHHLASGVGPVLDWTTARAMVLARLVSIAQGASGASEGTIARLIDLLN 134
Query 140 ENVIPVIPSEGSVGASGDLTPLSYIAGVLVGERE-VYYQGKIIPVQQVYQQKAIQPLTLR 198
+ P +PS G+VGASGDLTPL+++ L G + + G + + ++ +QPL L
Sbjct 135 SELAPAVPSRGTVGASGDLTPLAHMVLCLQGRGDFLDRDGTRLDGAEGLRRGRLQPLDLS 194
Query 199 PKEGLALMNGTAVMTAIACLNYKRAEQIAQTATLVTAINVLALEGNPTHFDEVLFAQKPH 258
++ LAL+NGT+ MT IA +N + A +TA+ L G + L +PH
Sbjct 195 HRDALALVNGTSAMTGIALVNAHACRHLGNWAVALTALLAECLRGRTEAWAAALSDLRPH 254
Query 259 TGQQKIAAQLRDWLNSEVQTAHQ---SPRL------------QDRYSLRCAPHVIGVFED 303
GQ+ AA+LR ++ + RL QD YSLRCAP V+G D
Sbjct 255 PGQKDAAARLRARVDGSARVVRHVIAERRLDAGDIGTEPEAGQDAYSLRCAPQVLGAGFD 314
Query 304 SKVWLRQFIENELNSSNDNPLIDP-VNLRVLHGGHFYGGHIAQAMDSLKIMIANIADLMD 362
+ W + + ELN+ DNP+ P ++ LHGG+F G H+A D+L + +A L +
Sbjct 315 TLAWHDRVLTIELNAVTDNPVFPPDGSVPALHGGNFMGQHVALTSDALATAVTVLAGLAE 374
Query 363 RQLAQLVDHKMNHGLPRNLTGATAERLPLNHGFKAVQIGVSAWTAEALKQTLSASIFSRS 422
RQ+A+L D ++N GLP L A LN GF Q+ +A AE ++ T ASI S S
Sbjct 375 RQIARLTDERLNRGLPPFLHRGPA---GLNSGFMGAQVTATALLAE-MRATGPASIHSIS 430
Query 423 TECHNQDKVSMGTIAARDATRIIVLTEQVMA--ALCCASIQAIHLKQLAQQLSPTLRAFS 480
T NQD VS+GTIAAR I +++A ALC A + +SP +
Sbjct 431 TNAANQDVVSLGTIAARLCREKIDRWAEILAILALCLAQAAELRCGSGLDGVSPAGKKLV 490
Query 481 AWTLHSLALVIEDRPLQTEL 500
+ DRPL E+
Sbjct 491 QALREQFPPLETDRPLGQEI 510
Lambda K H a alpha
0.321 0.134 0.396 0.792 4.96
Gapped
Lambda K H a alpha sigma
0.267 0.0410 0.140 1.90 42.6 43.6
Effective search space used: 6245360
Database: 898457986823ca98d6cf5d1db8e1f382.SwissProt.fasta
Posted date: May 9, 2024 11:07 AM
Number of letters in database: 14,912
Number of sequences in database: 28
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Neighboring words threshold: 11
Window for multiple hits: 40
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Data ...
