BLASTP 2.12.0+
Reference: Stephen F. Altschul, Thomas L. Madden, Alejandro A.
Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J.
Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of
protein database search programs", Nucleic Acids Res. 25:3389-3402.
Reference for composition-based statistics: Alejandro A. Schaffer,
L. Aravind, Thomas L. Madden, Sergei Shavirin, John L. Spouge, Yuri
I. Wolf, Eugene V. Koonin, and Stephen F. Altschul (2001),
"Improving the accuracy of PSI-BLAST protein database searches with
composition-based statistics and other refinements", Nucleic Acids
Res. 29:2994-3005.
Database: dcb1981d30e22000da9d974ea6baf30a.SwissProt.fasta
11 sequences; 5,413 total letters
Query= ACIAD0623
Length=597
Score E
Sequences producing significant alignments: (Bits) Value
Q5LLW7 3-methylmercaptopropionyl-CoA dehydrogenase [Ruegeria pome... 403 2e-137
Q0AVM4 Butyryl-CoA dehydrogenase Swol_1933 [Syntrophomonas wolfei... 305 4e-99
Q3L887 Broad-specificity linear acyl-CoA dehydrogenase FadE5 [Myc... 292 4e-94
O53666 Broad-specificity linear acyl-CoA dehydrogenase FadE5 [Myc... 289 6e-93
Q0AVA8 Butyryl-CoA dehydrogenase Swol_2052 [Syntrophomonas wolfei... 285 2e-91
P45857 Acyl-CoA dehydrogenase [Bacillus subtilis (strain 168)] 145 1e-41
G3KIM8 Acryloyl-CoA reductase (NADH) [Anaerotignum propionicum] 129 8e-36
P52042 Acyl-CoA dehydrogenase, short-chain specific [Clostridium ... 128 1e-35
Q06319 Acyl-CoA dehydrogenase, short-chain specific [Megasphaera ... 124 2e-34
Q54IM8 Isobutyryl-CoA dehydrogenase, mitochondrial [Dictyostelium... 125 3e-34
P70584 Short/branched chain specific acyl-CoA dehydrogenase, mito... 125 3e-34
>Q5LLW7 3-methylmercaptopropionyl-CoA dehydrogenase [Ruegeria
pomeroyi (strain ATCC 700808 / DSM 15171 / DSS-3)]
Length=588
Score = 403 bits (1036), Expect = 2e-137
Identities = 233/588 (40%), Positives = 327/588 (56%), Gaps = 13/588 (2%)
Query 7 YNAPLADMRFILNDVFNAEQFWQANENLAHIDAATAEAILEEMAKFAQNVTSPLNRTGDE 66
Y AP+ D+ F + + Q +A + + I+ A A LEE +F + +PL+ GD
Sbjct 3 YQAPVRDIMFAIEHLSQWPQV-EALQTYSEIELDDARAALEEFGRFCGEMIAPLSTIGDT 61
Query 67 EGAHYDQGQVTTPAGFKDAFQQYAQGGWIGLGADEEWGGQGMPKMLTVLADEMLFATNPS 126
EGA + G+V P G+K A+ Q+ GW L E GG G+PK++ A E++ + + S
Sbjct 62 EGARLENGRVVLPEGYKTAYDQFVDMGWQSLSHPAEHGGMGLPKVVGAAATEIVNSADMS 121
Query 127 FMLYPLLSVGAGMALNSYASQEQKETYLPKIYSGEWSGTMCLTEPHAGTDLGIIKTKAEP 186
F L PLL+ GA AL+ S QK YL K+ +G WSGTM LTEP AG+DL ++ A P
Sbjct 122 FGLCPLLTNGAIDALSITGSDAQKAFYLDKLITGRWSGTMNLTEPQAGSDLSRVRCTAVP 181
Query 187 NVDGSYHITGTKIFITGGDHDLSQNIIHLVLAKTPDAPAGSRGISLFIVPKFLVNEDGSL 246
DG+Y I+GTKIFIT G+HDLS+NI+HLVLA+TPDAP G RG+SLF+VPK L E G
Sbjct 182 QDDGTYAISGTKIFITFGEHDLSENIVHLVLARTPDAPEGVRGLSLFVVPKLLAGEGGET 241
Query 247 GERNAVGPGSIEHKMGIKASATCVMNFDGAKGFLVGKENEGLAAMFVMMNYERLSMGIQG 306
+RN +G S+EHK+G++AS T VM +D A G+LVG+EN GL MF+MM R ++G+QG
Sbjct 242 SQRNTLGCVSLEHKLGVRASPTAVMEYDNATGYLVGEENSGLRYMFIMMTSARYAVGVQG 301
Query 307 LGASEFAYQNAAQYATDRLQGRSASGVQSPNKPADSILVHGDVRRMLLNVRANNEASRAF 366
+ +E AYQ+A YA DR+Q R G P I+ H DVRRMLL +RA E RA
Sbjct 302 VAIAERAYQHALSYARDRIQSRPVDGSAQDAVP---IIQHPDVRRMLLRMRALTEGGRAL 358
Query 367 AVYVGQQLDITKFSTDPEAVKKANNRVALLTPIAKAYLTDTAFQATLDAQMCFGGHGYIR 426
A+ G LD+ + + EA +A + L P+ K + T+ A + GG G+I
Sbjct 359 AIATGGWLDLAEHGPE-EARAEAQSMAEFLVPLVKGFCTERAVEVASLGVQIHGGMGFIE 417
Query 427 EWGMEQCVRDLRIAQIYEGTNGVQSQDLIGRKTIKCGGAF---IAEYISEIRDFTNTLGA 483
E G+ Q RD RI IYEGT +Q+ DL+GRK ++ GG AE I+ + GA
Sbjct 418 ETGVAQFYRDARILPIYEGTTAIQANDLLGRKVLRDGGRTARRFAEMIAATEGELSKGGA 477
Query 484 DLNFIKDATLDAATEVEAITQFIIEQAAESAEFPNAAAVDYLHAVGLLSFAYMFAKISAA 543
I +A A ++ A + A +V +L G L+ + + A
Sbjct 478 AAQRIAQRLAEARAAFAAGLDHLLATAGQDPNRAYAGSVPFLMLTGNLATGWQLGLSALA 537
Query 544 -----AKEKSGEFYQNKLALAQYFVGRILPELESRIKKIEAGSDLVMS 586
AK EF Q K+A A F ++L E + +I D +++
Sbjct 538 AEAELAKGGDAEFLQAKIATADIFAQQVLVECSAEHSRITDTGDSLLT 585
>Q0AVM4 Butyryl-CoA dehydrogenase Swol_1933 [Syntrophomonas wolfei
subsp. wolfei (strain DSM 2245B / Goettingen)]
Length=610
Score = 305 bits (781), Expect = 4e-99
Identities = 202/611 (33%), Positives = 308/611 (50%), Gaps = 32/611 (5%)
Query 7 YNAPLADMRFILNDVFNAEQFWQANENLAHIDAATAEAILEEMAKFAQNVTSPLNRTGDE 66
Y + D++F + + + + + + +A L+ K ++V P N+ D+
Sbjct 6 YLYQMRDIKFAVKEWLDMNKLLSCDAYKDYYGIDDIDAFLDVNFKVCRDVLCPANKEADD 65
Query 67 EGAHY---DQGQVTTPAGFKDAFQQYAQGGWIGLGADEEWGGQGMPKMLTVLADEMLFAT 123
G + D V TP FK+A+ + G +D G+ MP + EM
Sbjct 66 PGCKFVGGDTQAVITPEVFKNAYNTVCEAGLGPQFSDRSAEGR-MPLVWEAPILEMQSGA 124
Query 124 NPSFMLYPLLSVGAGMALNSYASQEQKETYLPKIYSGEWSGTMCLTEPHAGTDLGIIKTK 183
+PS +++ L+ GA + AS+E KE +LPK+YSGEW GTM LTEP AG+++G + TK
Sbjct 125 SPSIVMFWCLTAGACTVIQHNASEELKERFLPKMYSGEWGGTMGLTEPGAGSEVGAVATK 184
Query 184 AEP-NVDGSYHITGTKIFITGGDHDLSQNIIHLVLAKTPDAPAGSRGISLFIVPKFLVNE 242
P + G Y I G K FIT GDHDL+ NIIHLVLAKTPDA G+ GI+ IVPKF VNE
Sbjct 185 CFPTDTPGLYKIKGQKCFITSGDHDLASNIIHLVLAKTPDAKPGTSGINCLIVPKFWVNE 244
Query 243 DGSLGERNAVGPGSIEHKMGIKASATCVMNF---DGAKGFLVGK-----ENEGLAAMFVM 294
DG+ G N V IEHKMGI S+T ++F D G+++G +G+A MF M
Sbjct 245 DGTQGAWNDVTSTGIEHKMGIHGSSTLSLSFGENDNCYGWMIGDGPVDGRGKGMAQMFQM 304
Query 295 MNYERLSMGIQGLGASEFAYQNAAQYATDRLQGRSASGVQSPNKPADSILVHGDVRRMLL 354
MN ERL+ G G AY A Y R+Q + P P+ I+ H DVRRMLL
Sbjct 305 MNEERLNTGTFAQGCIGSAYYAALDYCKMRVQSPKFT---DPKGPSVRIIEHEDVRRMLL 361
Query 355 NVRANNEASRAFAVYVGQQLDITKFSTDPEAVKKANNRVALLTPIAKAYLTDTAFQATLD 414
++ EA RA D++ + DP + ++ + P+ KAY++D A+ +T
Sbjct 362 FQKSIMEACRALLYTTYFYQDLSHDAADPAEREYYDDMTMIQIPLCKAYVSDMAWISTEQ 421
Query 415 AQMCFGGHGYIREWGMEQCVRDLRIAQIYEGTNGVQSQDLIGRKTIKCGGAFIAEYISEI 474
A C GG+G+I E+ + RD +I ++EGTN +Q+QD RKT G + +++++I
Sbjct 422 AIQCLGGYGFIEEYAPAELARDCKIYSLWEGTNFIQAQDFNNRKTTMKKGEPMKKWVAQI 481
Query 475 RDFTNT----LGADLNFIKDATLDAATEVEAITQFIIEQAAESAEFPNAAAVDYLHAVGL 530
DF T AD + D A E+ + + A + + A LHA +
Sbjct 482 ADFLATKKDPAFADEFAMMDDAFSAYNEILSTKE---AWRASNPQLVQLFATRMLHAASM 538
Query 531 LSFAYMFAKISAAAKEKSGE---------FYQNKLALAQYFVGRILPELESRIKKIEAGS 581
+ + + A +K E FY+ K+A A+++V ++P + +K ++
Sbjct 539 MICGKLMLDQALLAAKKLAELGEDHFDAMFYKGKIATARFYVMNVVPGVFGTLKAMKVAD 598
Query 582 DLVMSFTEDYF 592
+ E+ F
Sbjct 599 TSAIDMPEEAF 609
>Q3L887 Broad-specificity linear acyl-CoA dehydrogenase FadE5
[Mycolicibacterium smegmatis (strain ATCC 700084 / mc(2)155)]
Length=611
Score = 292 bits (747), Expect = 4e-94
Identities = 205/619 (33%), Positives = 315/619 (51%), Gaps = 38/619 (6%)
Query 4 MPIYNAPLADMRFILNDVFNAEQFWQANENLAHIDAATAEAILEEMAKFAQNVTSPLNRT 63
M Y + + D F L +VF ++ A++ + +DA TA +L E+A+ A+ +
Sbjct 1 MSHYKSNVRDQVFNLFEVFGVDKVLGADK-FSDLDADTAREMLTEIARLAEGPIAESFVE 59
Query 64 GDEEGAHYDQGQ--VTTPAGFKDAFQQYAQGGWIGLGADEEWGGQGMPKMLTVLADEMLF 121
GD +D VT P GFK + + GGW +G E GG MP+ L E +
Sbjct 60 GDRNPPVFDPETHTVTLPEGFKKSMRALFDGGWDKVGLAEHLGGIPMPRALQWALIEHIL 119
Query 122 ATNPSFMLYPLLSVGAGMALNSY--ASQEQKETYLPKIYSGEWSGTMCLTEPHAGTDLGI 179
NP+ +Y ++G GM+ Y + EQK+ G W TM LTEP AG+D+G
Sbjct 120 GANPAAYMY---AMGPGMSEIFYNNGTDEQKKWATIAAERG-WGATMVLTEPDAGSDVGA 175
Query 180 IKTKAEPNVDGSYHITGTKIFITGGDHD-LSQNIIHLVLAKTPDAPAGSRGISLFIVPKF 238
+TKA DG++HI G K FIT D D L +NI+HLVLA+ A G++G+SLF VPKF
Sbjct 176 GRTKAVQQPDGTWHIEGVKRFITSADSDDLFENIMHLVLARPEGAGPGTKGLSLFFVPKF 235
Query 239 -LVNEDGSLGERNAVGPGSIEHKMGIKASATCVMNFDG----AKGFLVGKENEGLAAMFV 293
+E G +GERN V ++EHKMG+K SATC ++ A G+LVG+ + G+A MF
Sbjct 236 HFDHETGEIGERNGVFVTNVEHKMGLKVSATCELSLGQHGIPAVGWLVGEVHNGIAQMFD 295
Query 294 MMNYERLSMGIQGLGASEFAYQNAAQYATDRLQGRSASGVQSPNKPADSILVHGDVRRML 353
++ R+ +G + + Y NA +YA +R+QG + + P +I H DVRR L
Sbjct 296 VIEQARMMVGTKAIATLSTGYLNALEYAKERVQGADMTQMTDKTAPRVTITHHPDVRRSL 355
Query 354 LNVRANNEASRAFAVYVG--QQLDITK--FSTDPEAVKKANNRVALLTPIAKAYLTDTAF 409
+ +A E RA +Y Q ++ + D + + N+ LL PI K + ++TA+
Sbjct 356 MTQKAYAEGLRAIYLYTATFQDAEVAQAVHGVDGDLAARVND---LLLPIVKGFGSETAY 412
Query 410 QATLDAQMCFGGHGYIREWGMEQCVRDLRIAQIYEGTNGVQSQDLIGRKTIKCGGAFIAE 469
++ GG G+++++ +EQ +RD +I +YEGT +Q+QD RK I+ G +A
Sbjct 413 AKLTESLQTLGGSGFLQDYPIEQYIRDSKIDSLYEGTTAIQAQDFFFRKIIRDKGQALAY 472
Query 470 YISEIRDF------TNTLGADLNFIKDATLDAATEVEAITQFII--EQAAESAEFPNAAA 521
EI F L + + A D ++T +++ ++ A S +
Sbjct 473 VAGEIEQFIKNENGNGRLKTERELLATALADVQGMAASLTGYLMAAQEDAASIYKVGLGS 532
Query 522 VDYLHAVGLLSFAYMFAKISAAAKEK--------SGEFYQNKLALAQYFVGRILPELESR 573
V +L AVG L ++ A+ +A A EK FY+ K+A A +F +LP L S
Sbjct 533 VRFLMAVGDLLSGWLLARQAAVAIEKLDAGATGADKSFYEGKIAAASFFAKNMLPLLTST 592
Query 574 IKKIEAGSDLVMSFTEDYF 592
+ IE + VM E F
Sbjct 593 RQIIENLDNDVMELDEAAF 611
>O53666 Broad-specificity linear acyl-CoA dehydrogenase FadE5
[Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv)]
Length=611
Score = 289 bits (739), Expect = 6e-93
Identities = 199/619 (32%), Positives = 305/619 (49%), Gaps = 38/619 (6%)
Query 4 MPIYNAPLADMRFILNDVFNAEQFWQANENLAHIDAATAEAILEEMAKFAQNVTSPLNRT 63
M Y + + D F L +V ++ E + +D TA +L E+++ A+ +
Sbjct 1 MSHYRSNVRDQVFNLFEVLGVDKALGHGE-FSDVDVDTARDMLAEVSRLAEGPVAESFVE 59
Query 64 GDEEGAHYDQG--QVTTPAGFKDAFQQYAQGGWIGLGADEEWGGQGMPKMLTVLADEMLF 121
GD +D V P FK + + GW +G DE GG MPK + E +
Sbjct 60 GDRNPPVFDPKTHSVMLPESFKKSVNAMLEAGWDKVGIDEALGGMPMPKAVVWALHEHIL 119
Query 122 ATNPSFMLYPLLSVGAGMALNSY--ASQEQKETYLPKIYSGEWSGTMCLTEPHAGTDLGI 179
NP+ +Y + GAG A Y ++EQK+ + G W TM LTEP AG+D+G
Sbjct 120 GANPAVWMY---AGGAGFAQILYHLGTEEQKKWAVLAAERG-WGSTMVLTEPDAGSDVGA 175
Query 180 IKTKAEPNVDGSYHITGTKIFITGGDH-DLSQNIIHLVLAKTPDAPAGSRGISLFIVPKF 238
+TKA DGS+HI G K FIT GD DL +NI HLVLA+ A G++G+SL+ VPKF
Sbjct 176 ARTKAVQQADGSWHIDGVKRFITSGDSGDLFENIFHLVLARPEGAGPGTKGLSLYFVPKF 235
Query 239 LVN-EDGSLGERNAVGPGSIEHKMGIKASATCVMNFDG----AKGFLVGKENEGLAAMFV 293
L + E G GERN V ++EHKMG+K SATC + F AKG+LVG+ + G+A MF
Sbjct 236 LFDVETGEPGERNGVFVTNVEHKMGLKVSATCELAFGQHGVPAKGWLVGEVHNGIAQMFE 295
Query 294 MMNYERLSMGIQGLGASEFAYQNAAQYATDRLQGRSASGVQSPNKPADSILVHGDVRRML 353
++ R+ +G + + Y NA QYA R+QG + + P +I H DVRR L
Sbjct 296 VIEQARMMVGTKAIATLSTGYLNALQYAKSRVQGADLTQMTDKTAPRVTITHHPDVRRSL 355
Query 354 LNVRANNEASRAFAVYVGQQLDI----TKFSTDPEAVKKANNRVALLTPIAKAYLTDTAF 409
+ +A E RA +Y D D + K N+ L+ P+ K ++ A+
Sbjct 356 MTQKAYAEGLRALYLYTATFQDAAVAEVVHGVDAKLAVKVND---LMLPVVKGVGSEQAY 412
Query 410 QATLDAQMCFGGHGYIREWGMEQCVRDLRIAQIYEGTNGVQSQDLIGRKTIKCGGAFIAE 469
++ GG G+++++ +EQ +RD +I +YEGT +Q+QD RK ++ G +A
Sbjct 413 AKLTESLQTLGGSGFLQDYPIEQYIRDAKIDSLYEGTTAIQAQDFFFRKIVRDKGVALAH 472
Query 470 YISEIRDFTNT------LGADLNFIKDATLDAATEVEAITQFII--EQAAESAEFPNAAA 521
+I++F ++ L + + A D A+T +++ +Q S +
Sbjct 473 VSGQIQEFVDSGAGNGRLKTERALLAKALTDVQGMAAALTGYLMAAQQDVTSLYKVGLGS 532
Query 522 VDYLHAVGLLSFAYMF--------AKISAAAKEKSGEFYQNKLALAQYFVGRILPELESR 573
V +L +VG L ++ A + A A FY+ K+A+A +F LP L S
Sbjct 533 VRFLMSVGDLIIGWLLQRQAAVAVAALDAGATGDERSFYEGKVAVASFFAKNFLPLLTST 592
Query 574 IKKIEAGSDLVMSFTEDYF 592
+ IE + +M E F
Sbjct 593 REVIETLDNDIMELDEAAF 611
>Q0AVA8 Butyryl-CoA dehydrogenase Swol_2052 [Syntrophomonas wolfei
subsp. wolfei (strain DSM 2245B / Goettingen)]
Length=610
Score = 285 bits (728), Expect = 2e-91
Identities = 196/601 (33%), Positives = 300/601 (50%), Gaps = 28/601 (5%)
Query 13 DMRFILNDVFNAEQFWQANENLAHIDAATAEAILEEMAKFAQNVTSPLNRTGDEEGAHYD 72
D++F + + + + + + A +AI + K ++V P N+ DE G +
Sbjct 12 DIKFQIKEWLDINKILSLDAYKDYYGADDFDAICDVNFKICRDVICPANKESDEIGMKHV 71
Query 73 QGQ---VTTPAGFKDAFQQYAQGGWIGLGADEEWGGQGMPKMLTVLADEMLFATNPSFML 129
G V +P FK + + G D + G+ MP EM +P+ ++
Sbjct 72 GGNEKAVISPDVFKTVYNTVIEAGMGPQFGDRQVEGR-MPLYWYAPILEMQTGASPAMVM 130
Query 130 YPLLSVGAGMALNSYASQEQKETYLPKIYSGEWSGTMCLTEPHAGTDLGIIKTKAEP-NV 188
L+ GA L S+E +E +LPK+YSGEW G+MCLTEP AG+++G + TK P +
Sbjct 131 LWCLTQGATTVLQYNLSKELQERFLPKMYSGEWGGSMCLTEPGAGSEVGAVSTKCFPTDT 190
Query 189 DGSYHITGTKIFITGGDHDLSQNIIHLVLAKTPDAPAGSRGISLFIVPKFLVNEDGSLGE 248
G + + G K FIT GD D NIIHLVLAK PDA G+ GIS +VPKF VNEDGS+G
Sbjct 191 PGLWKVKGQKCFITTGDWDGVDNIIHLVLAKDPDAKPGTAGISCLVVPKFWVNEDGSMGA 250
Query 249 RNAVGPGSIEHKMGIKASATCVMNF---DGAKGFLVGK-----ENEGLAAMFVMMNYERL 300
N V IEHK+GI SATC + F D G+++G +G+A MF MMN ER+
Sbjct 251 WNDVTTTGIEHKLGIHGSATCSLAFGENDNCYGWMIGDGPVDGRGQGMAQMFQMMNEERI 310
Query 301 SMGIQGLGASEFAYQNAAQYATDRLQGRSASGVQSPNKPADSILVHGDVRRMLLNVRANN 360
+ GI LGA AY A +Y+ R+Q + ++ P P+ I+ H DVRRMLL ++
Sbjct 311 NTGIFSLGAFGAAYYAALEYSKARVQSKKST---DPKGPSVRIIEHEDVRRMLLLQKSVM 367
Query 361 EASRAFAVYVGQQLDITKFSTDPEAVKKANNRVALLTPIAKAYLTDTAFQATLDAQMCFG 420
EA RA +D++K + E + A + + P+ KAY++D A+ +A G
Sbjct 368 EACRALLYSSYYYIDMSKEAATEEEREYAEDMFMIQNPLCKAYVSDMAWVMCAEAIQVHG 427
Query 421 GHGYIREWGMEQCVRDLRIAQIYEGTNGVQSQDLIGRK-TIKCGGAFIAEYISEIRDFTN 479
G+G++ E+ RD +I ++EGTN +QSQD GRK T+K G F ++++EI DF
Sbjct 428 GYGFMEEYAPASLARDCKIYTLWEGTNFIQSQDFTGRKFTMKKGEPF-KKWLAEIGDFIA 486
Query 480 TLGADLNFIKDATLDAA-TEVEAITQFIIEQAAESAEFPNAAAVDYLHAVGLLSFAYMFA 538
+ A ++ A +I + + A +HA + +
Sbjct 487 NKKTPEFAAEFAMMEKAFAAFNSIIDMNAAWTTTNKQLKQLFATRIMHAAARVICGKLML 546
Query 539 KISAAAKEKSGE---------FYQNKLALAQYFVGRILPELESRIKKIEAGSDLVMSFTE 589
A K E FY+ KLA +++V ++PE+ + ++A + E
Sbjct 547 DQGLLAAGKLAELGDSHFDANFYKGKLASVKFYVMNVVPEIFGTEEAMKAADTSAIDCPE 606
Query 590 D 590
+
Sbjct 607 E 607
>P45857 Acyl-CoA dehydrogenase [Bacillus subtilis (strain 168)]
Length=379
Score = 145 bits (365), Expect = 1e-41
Identities = 118/369 (32%), Positives = 180/369 (49%), Gaps = 59/369 (16%)
Query 93 GWIGLGADEEWGGQGMPKMLTVLADEMLFATNPSFMLYPLLSVGAGMALNS---YASQEQ 149
G +G+ E++GG G + +LA + + S + +LSV + N + ++EQ
Sbjct 47 GLMGIPVPEQYGGAGADVVSYILAIHEI--SRISAAVGVILSVHTSVGTNPILYFGNEEQ 104
Query 150 KETYLPKIYSGEWSGTMCLTEPHAGTDLGIIKTKAEPNVDGSYHITGTKIFIT-GGDHDL 208
K Y+P + SG+ G LTEPH+G+D G ++T A +G Y + G+KIFIT GG D
Sbjct 105 KMKYIPNLASGDHLGAFALTEPHSGSDAGSLRTTAIKK-NGKYLLNGSKIFITNGGAAD- 162
Query 209 SQNIIHLVLAKT-PDAPAGSRGISLFIVPKFLVNEDGSLGERNAVG--PGSIEHKMGIKA 265
I++ A T PD G GIS FIV E+N G G E K+G+
Sbjct 163 ----IYITFALTAPDQ--GRHGISAFIV------------EKNTPGFTVGKKERKLGLYG 204
Query 266 SATCVMNFDGAK---GFLVGKENEGLAAMFVMMNYERLSMGIQGLGASEFAYQNAAQYAT 322
S T + FD A+ L+GKE +G +N R+ + Q LG +E A ++A YA
Sbjct 205 SNTTELIFDNAEVPEANLLGKEGDGFHIAMANLNVGRIGIAAQALGIAEAALEHAVDYAK 264
Query 323 DRLQ-GRSASGVQSPNKPADSILVHGDVRRMLLNVRANNEASRAFAVYVGQQLDITKFST 381
R+Q GR + Q + L ++ EA+R VY L +
Sbjct 265 QRVQFGRPIAANQG-------------ISFKLADMATRAEAARHL-VYHAADLHNRGLNC 310
Query 382 DPEAVKKANNRVALLTPIAKAYLTDTAFQATLDAQMCFGGHGYIREWGMEQCVRDLRIAQ 441
EA +AK + +D A +A LDA +GG+GY++++ +E+ +RD ++ Q
Sbjct 311 GKEA------------SMAKQFASDAAVKAALDAVQIYGGYGYMKDYPVERLLRDAKVTQ 358
Query 442 IYEGTNGVQ 450
IYEGTN +Q
Sbjct 359 IYEGTNEIQ 367
>G3KIM8 Acryloyl-CoA reductase (NADH) [Anaerotignum propionicum]
Length=394
Score = 129 bits (323), Expect = 8e-36
Identities = 108/384 (28%), Positives = 180/384 (47%), Gaps = 53/384 (14%)
Query 86 FQQYAQGGWIGLGADEEWGGQG---MPKMLTVLADEMLFATNPSFMLYPLLSVGAGMALN 142
F++ A+ G G+G +E+GG G + K++ V + S + L+ A A+
Sbjct 55 FKKMAEIGLTGIGIPKEFGGSGGGTLEKVIAVSEFGKKCMASASILSIHLI---APQAIY 111
Query 143 SYASQEQKETYLPKIYSGEWSGTMCLTEPHAGTDLGIIKTKA-EPNVDGSYHITGTKIFI 201
Y ++EQKETYLP++ G G LTEP+AG+D G +KT A + Y + GTK FI
Sbjct 112 KYGTKEQKETYLPRLTKGGELGAFALTEPNAGSDAGAVKTTAILDSQTNEYVLNGTKCFI 171
Query 202 TGGDHDLSQNIIHLVLAKTPDAPAGSRGISLFIVPKFLVNEDGSLGERNAVGPGSIEHKM 261
+GG LV+ + G +G+S IV E G+ G G +E KM
Sbjct 172 SGGG-----RAGVLVIFALTEPKKGLKGMSAIIV------EKGTPG----FSIGKVESKM 216
Query 262 GIKASATCVMNFDGAK---GFLVGKENEGLAAMFVMMNYERLSMGIQGLGASEFAYQNAA 318
GI S T + F+ + L+GKE +G ++ R+ +G Q +G +E A +
Sbjct 217 GIAGSETAELIFEDCRVPAANLLGKEGKGFKIAMEALDGARIGVGAQAIGIAEGAIDLSV 276
Query 319 QYATDRLQ-GRSASGVQSPNKPADSILVHGDVRRMLLNVRANNEASRAFAVYVGQQLDIT 377
+Y +R+Q G+ + +Q ++ + ++ A+RA + D
Sbjct 277 KYVHERIQFGKPIANLQG-------------IQWYIADMATKTAAARALVEFAAYLEDAG 323
Query 378 KFSTDPEAVKKANNRVALLTPIAKAYLTDTAFQATLDAQMCFGGHGYIREWGMEQCVRDL 437
K T A+ K N ++ A T A GG+GY++++ +E+ RD
Sbjct 324 KPFTKESAMCKLN-------------ASENARFVTNLALQIHGGYGYMKDYPLERMYRDA 370
Query 438 RIAQIYEGTNGVQSQDLIGRKTIK 461
+I +IYEGT+ + + +I R+ +K
Sbjct 371 KITEIYEGTSEIH-KVVIAREVMK 393
>P52042 Acyl-CoA dehydrogenase, short-chain specific [Clostridium
acetobutylicum (strain ATCC 824 / DSM 792 / JCM 1419 / LMG
5710 / VKM B-1787)]
Length=379
Score = 128 bits (321), Expect = 1e-35
Identities = 119/422 (28%), Positives = 190/422 (45%), Gaps = 62/422 (15%)
Query 43 EAILEEMAKFAQNVTSPLNRTGDEEGAHYDQGQVTTPAGFKDAFQQYAQGGWIGLGADEE 102
E + + + +FA+N P+ DE T + ++ Q G +G+ +E
Sbjct 10 ELVRQMVREFAENEVKPIAAEIDE-----------TERFPMENVKKMGQYGMMGIPFSKE 58
Query 103 WGGQGMPKMLTVLADEMLFAT--NPSFMLYPLLSVGAGMALNSYASQEQKETYLPKIYSG 160
+GG G + ++A E L +L S+ A + +N + ++EQK+ YL + G
Sbjct 59 YGGAGGDVLSYIIAVEELSKVCGTTGVILSAHTSLCASL-INEHGTEEQKQKYLVPLAKG 117
Query 161 EWSGTMCLTEPHAGTDLGIIKTKAEPNVDGSYHITGTKIFIT-GGDHDLSQNIIHLVLAK 219
E G LTEP+AGTD G +T A D Y I G+KIFIT GG D V+
Sbjct 118 EKIGAYGLTEPNAGTDSGAQQTVAVLEGD-HYVINGSKIFITNGGVADT------FVIFA 170
Query 220 TPDAPAGSRGISLFIVPKFLVNEDGSLGERNAVGPGSIEHKMGIKASATCVMNFDG---A 276
D G++GIS FI+ K G +E K+GI+AS+T + F+
Sbjct 171 MTDRTKGTKGISAFIIEKGF----------KGFSIGKVEQKLGIRASSTTELVFEDMIVP 220
Query 277 KGFLVGKENEGLAAMFVMMNYERLSMGIQGLGASEFAYQNAAQYATDRLQ-GRSASGVQS 335
++GKE +G ++ R+ + Q LG +E A+ A Y +R Q GRS Q
Sbjct 221 VENMIGKEGKGFPIAMKTLDGGRIGIAAQALGIAEGAFNEARAYMKERKQFGRSLDKFQG 280
Query 336 PNKPADSILVHGDVRRMLLNVRANNEASRAFAVYVGQQLDITKFSTDPEAVKKANNRVAL 395
+ M+ ++ E++R + VY L K+A +
Sbjct 281 -------------LAWMMADMDVAIESAR-YLVYKAAYL------------KQAGLPYTV 314
Query 396 LTPIAKAYLTDTAFQATLDAQMCFGGHGYIREWGMEQCVRDLRIAQIYEGTNGVQSQDLI 455
AK + + A T A FGG+GY +++ +E+ +RD +I +IYEGT+ VQ +
Sbjct 315 DAARAKLHAANVAMDVTTKAVQLFGGYGYTKDYPVERMMRDAKITEIYEGTSEVQKLVIS 374
Query 456 GR 457
G+
Sbjct 375 GK 376
Score = 18.5 bits (36), Expect = 7.4
Identities = 9/41 (22%), Positives = 18/41 (44%), Gaps = 0/41 (0%)
Query 16 FILNDVFNAEQFWQANENLAHIDAATAEAILEEMAKFAQNV 56
FI+ F + + L ++T E + E+M +N+
Sbjct 184 FIIEKGFKGFSIGKVEQKLGIRASSTTELVFEDMIVPVENM 224
>Q06319 Acyl-CoA dehydrogenase, short-chain specific [Megasphaera
elsdenii]
Length=383
Score = 124 bits (312), Expect = 2e-34
Identities = 114/380 (30%), Positives = 171/380 (45%), Gaps = 57/380 (15%)
Query 83 KDAFQQYAQGGWIGLGADEEWGGQGMPK---MLTVLADEMLFATNPSFMLYPLLSVGAGM 139
K+ + G G +E++GG G + +LA E L + + LS +
Sbjct 39 KELIDELLSLGITGAYFEEKYGGSGDDGGDVLSYILAVEELAKYDAGVAI--TLSATVSL 96
Query 140 ALN---SYASQEQKETYLPKIYSGEWSGTMCLTEPHAGTDLGIIKTKAEPNVDGSYHITG 196
N + ++ QKE +L + G G LTEP+AGTD +T A N DG+Y + G
Sbjct 97 CANPIWQFGTEAQKEKFLVPLVEGTKLGAFGLTEPNAGTDASGQQTIATKNDDGTYTLNG 156
Query 197 TKIFIT-GGDHDLSQNIIHLVLAKTPDAPAGSRGISLFIVPKFLVNEDGSLGERNAVGPG 255
+KIFIT GG D I++V A T D G+ GI+ FI+ EDG+ G G
Sbjct 157 SKIFITNGGAAD-----IYIVFAMT-DKSKGNHGITAFIL------EDGTPG----FTYG 200
Query 256 SIEHKMGIKASATCVMNFDGAK---GFLVGKENEGLAAMFVMMNYERLSMGIQGLGASEF 312
E KMGI S T + F K ++G+E +G + ++ R+ + Q LG +E
Sbjct 201 KKEDKMGIHTSQTMELVFQDVKVPAENMLGEEGKGFKIAMMTLDGGRIGVAAQALGIAEA 260
Query 313 AYQNAAQYATDRLQ-GRSASGVQSPN-KPADSILVHGDVRRMLLNVRANNEASRAFAVYV 370
A +A +Y+ R+Q G+ QS + K AD + R ++ + + F V
Sbjct 261 ALADAVEYSKQRVQFGKPLCKFQSISFKLADMKMQIEAARNLVYKAACKKQEGKPFTVDA 320
Query 371 GQQLDITKFSTDPEAVKKANNRVALLTPIAKAYLTDTAFQATLDAQMCFGGHGYIREWGM 430
IAK +D A + T +A FGG+GY E+ +
Sbjct 321 A---------------------------IAKRVASDVAMRVTTEAVQIFGGYGYSEEYPV 353
Query 431 EQCVRDLRIAQIYEGTNGVQ 450
+ +RD +I QIYEGTN VQ
Sbjct 354 ARHMRDAKITQIYEGTNEVQ 373
>Q54IM8 Isobutyryl-CoA dehydrogenase, mitochondrial [Dictyostelium
discoideum]
Length=416
Score = 125 bits (313), Expect = 3e-34
Identities = 98/370 (26%), Positives = 176/370 (48%), Gaps = 43/370 (12%)
Query 83 KDAFQQYAQGGWIGLGADEEWGGQGMPKMLTVLADEMLFATNPSFMLYPLLSVGAGMALN 142
+D ++ A+ G+ G+ E+ GG G+ ++ + E L + + S + + ++
Sbjct 73 RDVMREAAELGFGGIYVREDVGGSGLSRLDASIIIEALASADVSTTAFISIHNMCAGLID 132
Query 143 SYASQEQKETYLPKIYSGEWSGTMCLTEPHAGTDLGIIKTKAEPNVDGSYHITGTKIFIT 202
Y ++EQ++ +LP + S E + CLTEP +G+D G + TKA + D Y + G+K FI+
Sbjct 133 IYGTEEQRKKFLPSLVSMEKIASYCLTEPGSGSDAGSLSTKATKDGD-HYILNGSKAFIS 191
Query 203 GGDHDLSQNIIHLVLAKTPDAPAGSRGISLFIVPKFLVNEDGSLGERNAVGPGSIEHKMG 262
GG + ++LV+ +T A G +GIS +V K + + G E K+G
Sbjct 192 GG----GDSEVYLVMVRT-GAEKGPKGISCLLVEK----------DTPGLSFGKKEEKLG 236
Query 263 IKASATCVMNFDGAK---GFLVGKENEGLAAMFVMMNYERLSMGIQGLGASEFAYQNAAQ 319
T + F+ + G L+GKE +G + +N R+++G LG ++ A
Sbjct 237 WNTQPTRALIFEDCRVPVGNLIGKEGQGFSIAMNALNGGRINIGACSLGGAQSCLVAARD 296
Query 320 YATDRLQGRSASGVQSPNKPADSILVHGDVRRMLLNVRANNEASRAFAVYVGQQLDITKF 379
+ R Q N+P + V+ + ++ ASR LD
Sbjct 297 HVKVRKQF---------NQPLEHFQA---VQFKMADMATKLHASRIMIRNAAAMLD---- 340
Query 380 STDPEAVKKANNRVALLTPIAKAYLTDTAFQATLDAQMCFGGHGYIREWGMEQCVRDLRI 439
+ DP A + +AK + D F+ T D+ FGG+GY++++ +E+ +RDLR+
Sbjct 341 AKDPSA--------HVYIAMAKLFACDECFKVTDDSLQLFGGYGYLKDYPVERYLRDLRV 392
Query 440 AQIYEGTNGV 449
+I EG++ V
Sbjct 393 HRILEGSDAV 402
>P70584 Short/branched chain specific acyl-CoA dehydrogenase,
mitochondrial [Rattus norvegicus]
Length=432
Score = 125 bits (313), Expect = 3e-34
Identities = 119/425 (28%), Positives = 192/425 (45%), Gaps = 65/425 (15%)
Query 35 AHIDAATAEAILEEMA--KFAQNVTSPLNRTGDEEGAHYDQGQVTTPAGFKDAFQQYAQG 92
A + T E I+ + A KFAQ +PL T DE K Q Q
Sbjct 52 APLQTFTDEDIMMQKAVKKFAQEQIAPLVSTMDENSKME-----------KSVIQGLFQQ 100
Query 93 GWIGLGADEEWGGQGMPKMLTVLADEMLFATNPSF-MLYPLLSVGAGMALNSYASQEQKE 151
G +G+ + ++GG + +VL E L + S +L + + + ++EQK
Sbjct 101 GMMGIEVEAKYGGTEASFLCSVLVIEELAKVDASVALLCDIQNTVINKLFRKHGTEEQKA 160
Query 152 TYLPKIYSGEWSGTMCLTEPHAGTDLGIIKTKAEPNVDGSYH-ITGTKIFITGGDHDLSQ 210
TYLPK+ + E G+ CL+E AG+D +KT+A+ + G+Y+ I G+K++I+ +H
Sbjct 161 TYLPKLVT-EKLGSFCLSEAGAGSDSFALKTRADKS--GNYYVINGSKMWISNAEHAE-- 215
Query 211 NIIHLVLAKTPDAPAGSRGISLFIVPKFLVNEDGSLGERNAVGPGSIEHKMGIKASATCV 270
+ LV A D P+G RGI+ F+V + E +G R E+KMGI+AS+TC
Sbjct 216 --LFLVFANV-DPPSGYRGITCFLVDRD--TEGFQIGRR--------ENKMGIRASSTCQ 262
Query 271 MNFDGAK---GFLVGKENEGLAAMFVMMNYERLSMGIQGLGASEFAYQNAAQYATDRLQ- 326
+ F+ K ++GK G +N R+ + Q LG ++ + Y +R+Q
Sbjct 263 LTFENVKVPETSVLGKIGHGYKYAIGSLNEGRIGIAAQMLGLAQGCFDYTIPYIKERMQF 322
Query 327 GRSASGVQSPNKPADSILVHGDVRRMLL-NVRANNEASRAFAVYVGQQLDITKFSTDPEA 385
G+ Q + + R+L N EA R F
Sbjct 323 GKRIFDFQGLQHQVAHVATQLEAARLLTYNAARLVEAGRPF------------------- 363
Query 386 VKKANNRVALLTPIAKAYLTDTAFQATLDAQMCFGGHGYIREWGMEQCVRDLRIAQIYEG 445
+K+A+ +AK Y ++ A T GG GY +++ +E+ RD +I IYEG
Sbjct 364 IKEAS--------MAKYYASEVAGLTTSKCIEWMGGVGYTKDYPVEKFFRDAKIGTIYEG 415
Query 446 TNGVQ 450
T+ +Q
Sbjct 416 TSNIQ 420
Lambda K H a alpha
0.318 0.134 0.388 0.792 4.96
Gapped
Lambda K H a alpha sigma
0.267 0.0410 0.140 1.90 42.6 43.6
Effective search space used: 2638345
Database: dcb1981d30e22000da9d974ea6baf30a.SwissProt.fasta
Posted date: May 19, 2024 8:15 PM
Number of letters in database: 5,413
Number of sequences in database: 11
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Neighboring words threshold: 11
Window for multiple hits: 40
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Data ...
