BLASTP 2.12.0+
Reference: Stephen F. Altschul, Thomas L. Madden, Alejandro A.
Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J.
Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of
protein database search programs", Nucleic Acids Res. 25:3389-3402.
Reference for composition-based statistics: Alejandro A. Schaffer,
L. Aravind, Thomas L. Madden, Sergei Shavirin, John L. Spouge, Yuri
I. Wolf, Eugene V. Koonin, and Stephen F. Altschul (2001),
"Improving the accuracy of PSI-BLAST protein database searches with
composition-based statistics and other refinements", Nucleic Acids
Res. 29:2994-3005.
Database: 593b982b1e5663d3b5a34f1ff897f3ee.SwissProt.fasta
15 sequences; 5,935 total letters
Query= ACIAD0694
Length=392
Score E
Sequences producing significant alignments: (Bits) Value
P45359 Acetyl-CoA acetyltransferase [Clostridium acetobutylicum (... 375 3e-132
P14611 Acetyl-CoA acetyltransferase [Cupriavidus necator (strain ... 357 9e-125
Q9ZHI1 Acetyl-CoA acetyltransferase [Chromobacterium violaceum (s... 353 2e-123
Q0AVM3 Acetyl-CoA acetyltransferase [Syntrophomonas wolfei subsp.... 347 9e-121
P45369 Acetyl-CoA acetyltransferase [Allochromatium vinosum (stra... 346 1e-120
Q9UQW6 Acetyl-CoA acetyltransferase [Schizosaccharomyces pombe (s... 343 3e-119
Q9I2A8 Acetyl-CoA acetyltransferase [Pseudomonas aeruginosa (stra... 341 1e-118
P44873 Acetyl-CoA acetyltransferase [Haemophilus influenzae (stra... 340 3e-118
P45363 Acetyl-CoA acetyltransferase [Thiocystis violacea] 338 2e-117
P76461 Acetyl-CoA acetyltransferase [Escherichia coli (strain K12)] 338 2e-117
Q4WCL5 Acetyl-CoA acetyltransferase erg10B, cytosolic [Aspergillu... 333 2e-115
B0YA65 Acetyl-CoA acetyltransferase erg10B, cytosolic [Aspergillu... 333 2e-115
Q04677 Acetyl-CoA acetyltransferase IB [Candida tropicalis] 332 8e-115
Q12598 Acetyl-CoA acetyltransferase IA [Candida tropicalis] 332 8e-115
Q9BWD1 Acetyl-CoA acetyltransferase, cytosolic [Homo sapiens] 325 3e-112
>P45359 Acetyl-CoA acetyltransferase [Clostridium acetobutylicum
(strain ATCC 824 / DSM 792 / JCM 1419 / LMG 5710 / VKM B-1787)]
Length=392
Score = 375 bits (964), Expect = 3e-132
Identities = 187/390 (48%), Positives = 264/390 (68%), Gaps = 1/390 (0%)
Query 1 MTEIVIVNGARTAMGGFQGALAPLTATDLGAVTIKEAIYRSGLQPTDIEEVIMGCVLPAG 60
M E+VI + RTA+G + +L + A DLGA IKEA+ ++G++P D+ EVI+G VL AG
Sbjct 1 MKEVVIASAVRTAIGSYGKSLKDVPAVDLGATAIKEAVKKAGIKPEDVNEVILGNVLQAG 60
Query 61 LKQGPARQAMRKAGLPDTTGAVTINKLCGSGMKAVMQAVDMIKAGSAEIVIAGGMESMSN 120
L Q PARQA KAGLP A+TINK+CGSG++ V A +IKAG A+++IAGGME+MS
Sbjct 61 LGQNPARQASFKAGLPVEIPAMTINKVCGSGLRTVSLAAQIIKAGDADVIIAGGMENMSR 120
Query 121 APYVLPKARSGYRMGHGEIKDHMFLDGLEDAETGRLMGSFAQDMANTRGYTREQMDDFAI 180
APY+ AR GYRMG+ + D M DGL DA MG A+++A +RE+ D+FA+
Sbjct 121 APYLANNARWGYRMGNAKFVDEMITDGLWDAFNDYHMGITAENIAERWNISREEQDEFAL 180
Query 181 RSLKRAQNAITEGYFKAEIVPVTVSSRKGDVIIEQDEQP-LNAKIDKIPSLKPAFAKDGT 239
S K+A+ AI G FK EIVPV + RKG+ +++ DE P + I+ + LKPAF KDGT
Sbjct 181 ASQKKAEEAIKSGQFKDEIVPVVIKGRKGETVVDTDEHPRFGSTIEGLAKLKPAFKKDGT 240
Query 240 ITAANSSSISDGASALVLTSIENADQRGLKPLAKVIATASNSQHPSEFTIAPVGAIGKVL 299
+TA N+S ++D A+ LV+ S E A + G+KPLAK+++ S P+ P A +
Sbjct 241 VTAGNASGLNDCAAVLVIMSAEKAKELGVKPLAKIVSYGSAGVDPAIMGYGPFYATKAAI 300
Query 300 KKSGWNAQEVDLWEINEAFAMVTMCAIDDFELDAEKVNIHGGACALGHPVGSTGSRIILS 359
+K+GW E+DL E NEAFA ++ D + D KVN++GGA ALGHP+G++G+RI+++
Sbjct 301 EKAGWTVDELDLIESNEAFAAQSLAVAKDLKFDMNKVNVNGGAIALGHPIGASGARILVT 360
Query 360 LIHALQRTGGKKGIAALCIGGGEATAVAIE 389
L+HA+Q+ KKG+A LCIGGG+ TA+ +E
Sbjct 361 LVHAMQKRDAKKGLATLCIGGGQGTAILLE 390
>P14611 Acetyl-CoA acetyltransferase [Cupriavidus necator (strain
ATCC 17699 / DSM 428 / KCTC 22496 / NCIMB 10442 / H16 /
Stanier 337)]
Length=393
Score = 357 bits (915), Expect = 9e-125
Identities = 188/391 (48%), Positives = 261/391 (67%), Gaps = 2/391 (1%)
Query 1 MTEIVIVNGARTAMGGFQGALAPLTATDLGAVTIKEAIYRSGLQPTDIEEVIMGCVLPAG 60
MT++VIV+ ARTA+G F G+LA + A +LGAV IK A+ R+G++P + EVIMG VL AG
Sbjct 1 MTDVVIVSAARTAVGKFGGSLAKIPAPELGAVVIKAALERAGVKPEQVSEVIMGQVLTAG 60
Query 61 LKQGPARQAMRKAGLPDTTGAVTINKLCGSGMKAVMQAVDMIKAGSAEIVIAGGMESMSN 120
Q PARQA KAGLP A+TINK+CGSG+KAVM A + I AG AEIV+AGG E+MS
Sbjct 61 SGQNPARQAAIKAGLPAMVPAMTINKVCGSGLKAVMLAANAIMAGDAEIVVAGGQENMSA 120
Query 121 APYVLPKARSGYRMGHGEIKDHMFLDGLEDAETGRLMGSFAQDMANTRGYTREQMDDFAI 180
AP+VLP +R G+RMG ++ D M +DGL D MG A+++A G TRE D+FA+
Sbjct 121 APHVLPGSRDGFRMGDAKLVDTMIVDGLWDVYNQYHMGITAENVAKEYGITREAQDEFAV 180
Query 181 RSLKRAQNAITEGYFKAEIVPVTVSSRKGDVIIEQDEQPL--NAKIDKIPSLKPAFAKDG 238
S +A+ A G F EIVPV + RKGD + + ++ + A +D + LKPAF K G
Sbjct 181 GSQNKAEAAQKAGKFDEEIVPVLIPQRKGDPVAFKTDEFVRQGATLDSMSGLKPAFDKAG 240
Query 239 TITAANSSSISDGASALVLTSIENADQRGLKPLAKVIATASNSQHPSEFTIAPVGAIGKV 298
T+TAAN+S ++DGA+A+V+ S A + GL PLA + + A+ P + PV A +
Sbjct 241 TVTAANASGLNDGAAAVVVMSAAKAKELGLTPLATIKSYANAGVDPKVMGMGPVPASKRA 300
Query 299 LKKSGWNAQEVDLWEINEAFAMVTMCAIDDFELDAEKVNIHGGACALGHPVGSTGSRIIL 358
L ++ W Q++DL EINEAFA + D KVN++GGA A+GHP+G++G RI++
Sbjct 301 LSRAEWTPQDLDLMEINEAFAAQALAVHQQMGWDTSKVNVNGGAIAIGHPIGASGCRILV 360
Query 359 SLIHALQRTGGKKGIAALCIGGGEATAVAIE 389
+L+H ++R KKG+A+LCIGGG A+A+E
Sbjct 361 TLLHEMKRRDAKKGLASLCIGGGMGVALAVE 391
>Q9ZHI1 Acetyl-CoA acetyltransferase [Chromobacterium violaceum
(strain ATCC 12472 / DSM 30191 / JCM 1249 / NBRC 12614 / NCIMB
9131 / NCTC 9757)]
Length=392
Score = 353 bits (906), Expect = 2e-123
Identities = 186/389 (48%), Positives = 257/389 (66%), Gaps = 2/389 (1%)
Query 3 EIVIVNGARTAMGGFQGALAPLTATDLGAVTIKEAIYRSGLQPTDIEEVIMGCVLPAGLK 62
E+ IV RTA+G F G LA + A +LGA IK + ++G++P D+ EVI+G VL AG
Sbjct 2 EVAIVAAQRTAIGSFGGGLAKIPAPELGATVIKALLEKTGVKPEDVSEVILGQVLTAGSG 61
Query 63 QGPARQAMRKAGLPDTTGAVTINKLCGSGMKAVMQAVDMIKAGSAEIVIAGGMESMSNAP 122
Q PARQA+ KAGLP TT A T+N +CGSG++AV A I AG A+IVIAGG ESMS +P
Sbjct 62 QNPARQALIKAGLPVTTPATTLNVVCGSGLRAVHLAAQAILAGDADIVIAGGQESMSLSP 121
Query 123 YVLPKARSGYRMGHGEIKDHMFLDGLEDAETGRLMGSFAQDMANTRGYTREQMDDFAIRS 182
++LP +R G+RMG+ ++ D M DGL DA MG A+++A G RE+ D F+++S
Sbjct 122 HILPGSRDGFRMGNAQLVDTMVNDGLTDAYNAYHMGITAENVAAKYGIGREEQDAFSLQS 181
Query 183 LKRAQNAITEGYFKAEIVPVTVSSRKGDVIIEQDEQPL--NAKIDKIPSLKPAFAKDGTI 240
+RA A G F+ EIVPV V RKGD + ++ + +A D + L+PAF KDGT+
Sbjct 182 QQRAAAAQKAGKFRDEIVPVLVPQRKGDPLAFDADEFIKHDASADGLAKLRPAFKKDGTV 241
Query 241 TAANSSSISDGASALVLTSIENADQRGLKPLAKVIATASNSQHPSEFTIAPVGAIGKVLK 300
TA N+S I+DGA+A++L S + ADQ GLKPLA + A P I PV A K L
Sbjct 242 TAGNASGINDGAAAVLLMSTQKADQLGLKPLAIIKGYALTGCEPEIMGIGPVSATRKALS 301
Query 301 KSGWNAQEVDLWEINEAFAMVTMCAIDDFELDAEKVNIHGGACALGHPVGSTGSRIILSL 360
K+GW +++DL E NEAFA + + ++KVN++GGA ALGHP+G++G R++++L
Sbjct 302 KAGWTVEDLDLVEANEAFAAQALGVAKELGWGSDKVNVNGGAIALGHPIGASGCRVLVTL 361
Query 361 IHALQRTGGKKGIAALCIGGGEATAVAIE 389
+H +QR G KKG+A LCIGGG A+A+E
Sbjct 362 LHEMQRRGAKKGLATLCIGGGMGVALAVE 390
>Q0AVM3 Acetyl-CoA acetyltransferase [Syntrophomonas wolfei subsp.
wolfei (strain DSM 2245B / Goettingen)]
Length=396
Score = 347 bits (889), Expect = 9e-121
Identities = 179/393 (46%), Positives = 255/393 (65%), Gaps = 4/393 (1%)
Query 3 EIVIVNGARTAMGGFQGALAPLTATDLGAVTIKEAIYRSGLQPTDIEEVIMGCVLPAGLK 62
E+V+V RT +G F G L + + LGA+ + EAI R+G++ I+EVI GCVL AGL
Sbjct 4 EVVLVGACRTPVGTFGGTLKDVGSAQLGAIVMGEAIKRAGIKAEQIDEVIFGCVLQAGLG 63
Query 63 QGPARQAMRKAGLPDTTGAVTINKLCGSGMKAVMQAVDMIKAGSAEIVIAGGMESMSNAP 122
Q ARQ M AG+P A TINK+CGSG++AV A +IKAG A+I++AGG E+M AP
Sbjct 64 QNVARQCMINAGIPKEVTAFTINKVCGSGLRAVSLAAQVIKAGDADIIMAGGTENMDKAP 123
Query 123 YVLPKARSGYRMG--HGEIKDHMFLDGLEDAETGRLMGSFAQDMANTRGYTREQMDDFAI 180
++LP AR GYRM G++ D M GL D G MG A+++ + G TRE+ D F
Sbjct 124 FILPNARWGYRMSMPKGDLIDEMVWGGLTDVFNGYHMGITAENINDMYGITREEQDAFGF 183
Query 181 RSLKRAQNAITEGYFKAEIVPVTVSSRKGDVIIEQDEQPLNAKIDKIPSLKPAFAKDGTI 240
RS A AI G FK EIVPV + +KGD++ + DE P + + + L PAF K G++
Sbjct 184 RSQTLAAQAIESGRFKDEIVPVVIKGKKGDIVFDTDEHPRKSTPEAMAKLAPAFKKGGSV 243
Query 241 TAANSSSISDGASALVLTSIENADQRGLKPLAKVIATASNSQHPSEFTIAPVGAIGKVLK 300
TA N+S I+D A+A+++ S E AD+ G+KP+AKV++ AS PS + P+ A K L+
Sbjct 244 TAGNASGINDAAAAVIVMSKEKADELGIKPMAKVVSYASGGVDPSVMGLGPIPASRKALE 303
Query 301 KSGWNAQEVDLWEINEAFAMVTMCAIDD--FELDAEKVNIHGGACALGHPVGSTGSRIIL 358
K+G ++DL E NEAFA ++ D + EKVN++GGA A+GHP+GS+G+RI++
Sbjct 304 KAGLTIDDIDLIEANEAFAAQSIAVARDLGWADKMEKVNVNGGAIAIGHPIGSSGARILV 363
Query 359 SLIHALQRTGGKKGIAALCIGGGEATAVAIELI 391
+L++ +Q+ G KKG+A LCIGGG TA+ +E +
Sbjct 364 TLLYEMQKRGSKKGLATLCIGGGMGTALIVEAL 396
>P45369 Acetyl-CoA acetyltransferase [Allochromatium vinosum (strain
ATCC 17899 / DSM 180 / NBRC 103801 / NCIMB 10441 / D)]
Length=394
Score = 346 bits (888), Expect = 1e-120
Identities = 177/388 (46%), Positives = 260/388 (67%), Gaps = 2/388 (1%)
Query 4 IVIVNGARTAMGGFQGALAPLTATDLGAVTIKEAIYRSGLQPTDIEEVIMGCVLPAGLKQ 63
IVIV+ R+A+G F G+L+ L+AT++G +K + R+GL P I+EVI+G VL AG+ Q
Sbjct 5 IVIVDAGRSAIGTFSGSLSSLSATEIGTAVLKGLLARTGLAPEQIDEVILGQVLTAGVGQ 64
Query 64 GPARQAMRKAGLPDTTGAVTINKLCGSGMKAVMQAVDMIKAGSAEIVIAGGMESMSNAPY 123
PARQ KAGLP + A+TINK+CGSG+KAV A+ I G A+IVIAGG ESMS + +
Sbjct 65 NPARQTTLKAGLPHSVPAMTINKVCGSGLKAVHLAMQAIACGDADIVIAGGQESMSQSSH 124
Query 124 VLPKARSGYRMGHGEIKDHMFLDGLEDAETGRLMGSFAQDMANTRGYTREQMDDFAIRSL 183
VLP++R G RMG +KD M +DGL DA MG+ A+++A G+TREQ D FA S
Sbjct 125 VLPRSRDGQRMGDWSMKDTMIVDGLWDAFNNYHMGTTAENIAQKYGFTREQQDAFAAASQ 184
Query 184 KRAQNAITEGYFKAEIVPVTVSSRKGD-VIIEQDEQPLN-AKIDKIPSLKPAFAKDGTIT 241
++ + A G F+ EI+P+ + RKGD + + DE P + + + L+PAF++DG++T
Sbjct 185 QKTEAAQKAGRFQDEIIPIEIPQRKGDPKVFDADEFPRHGTTAESLGKLRPAFSRDGSVT 244
Query 242 AANSSSISDGASALVLTSIENADQRGLKPLAKVIATASNSQHPSEFTIAPVGAIGKVLKK 301
A N+S I+DGA+ +V+ A + GLKP+A+++A AS P+ P+ A K L+K
Sbjct 245 AGNASGINDGAAMVVVMKESKAKELGLKPMARLVAFASAGVDPAIMGTGPIPASTKCLEK 304
Query 302 SGWNAQEVDLWEINEAFAMVTMCAIDDFELDAEKVNIHGGACALGHPVGSTGSRIILSLI 361
+GW ++DL E NEAFA M D D KVN++GGA A+GHP+G++G+R++++L+
Sbjct 305 AGWTPADLDLIEANEAFAAQAMSVNQDMGWDLSKVNVNGGAIAIGHPIGASGARVLVTLL 364
Query 362 HALQRTGGKKGIAALCIGGGEATAVAIE 389
+ +Q+ KKG+A LCIGGG+ A+A+E
Sbjct 365 YEMQKRDAKKGLATLCIGGGQGVALAVE 392
>Q9UQW6 Acetyl-CoA acetyltransferase [Schizosaccharomyces pombe
(strain 972 / ATCC 24843)]
Length=395
Score = 343 bits (879), Expect = 3e-119
Identities = 186/392 (47%), Positives = 250/392 (64%), Gaps = 2/392 (1%)
Query 2 TEIVIVNGARTAMGGFQGALAPLTATDLGAVTIKEAIYRSGLQPTDIEEVIMGCVLPAGL 61
TE+ IV+ RT MG F G+ A L AT LG++ IK A+ R ++P+D++EV MG V+ A L
Sbjct 4 TEVYIVSAVRTPMGSFGGSFASLPATKLGSIAIKGALERVNIKPSDVDEVFMGNVVSANL 63
Query 62 KQGPARQAMRKAGLPDTTGAVTINKLCGSGMKAVMQAVDMIKAGSAEIVIAGGMESMSNA 121
Q PARQ AGLP + T+NK+C SGMKA + I G+AEIV+AGG ESMSNA
Sbjct 64 GQNPARQCALGAGLPRSIVCTTVNKVCASGMKATILGAQTIMTGNAEIVVAGGTESMSNA 123
Query 122 PYVLPKARSGYRMGHGEIKDHMFLDGLEDAETGRLMGSFAQDMANTRGYTREQMDDFAIR 181
PY PK R G + G+ E+ D + DGL DA G MG+ A+ A R D FAI
Sbjct 124 PYYAPKNRFGAKYGNVELVDGLLRDGLSDAYDGLPMGNAAELCAEEHSIDRASQDAFAIS 183
Query 182 SLKRAQNAITEGYFKAEIVPVTVSSRKG--DVIIEQDEQPLNAKIDKIPSLKPAFAKDGT 239
S KRAQNA F+ EIVPV V +G + ++ +DE+P N DK+ S++ F +GT
Sbjct 184 SYKRAQNAQATKAFEQEIVPVEVPVGRGKPNKLVTEDEEPKNLNEDKLKSVRAVFKSNGT 243
Query 240 ITAANSSSISDGASALVLTSIENADQRGLKPLAKVIATASNSQHPSEFTIAPVGAIGKVL 299
+TAAN+S+++DGASALVL S + GLKPLAK+I +Q P FT +P AI K L
Sbjct 244 VTAANASTLNDGASALVLMSAAKVKELGLKPLAKIIGWGEAAQDPERFTTSPSLAIPKAL 303
Query 300 KKSGWNAQEVDLWEINEAFAMVTMCAIDDFELDAEKVNIHGGACALGHPVGSTGSRIILS 359
K +G A +VD +EINEAF++V + LD E+VNI+GG A+GHP+GS+GSRII +
Sbjct 304 KHAGIEASQVDYYEINEAFSVVAVANTKILGLDPERVNINGGGVAMGHPLGSSGSRIICT 363
Query 360 LIHALQRTGGKKGIAALCIGGGEATAVAIELI 391
L + L + K G+AA+C GGG A+++ IE +
Sbjct 364 LAYILAQKDAKIGVAAVCNGGGGASSIVIERV 395
>Q9I2A8 Acetyl-CoA acetyltransferase [Pseudomonas aeruginosa (strain
ATCC 15692 / DSM 22644 / CIP 104116 / JCM 14847 / LMG
12228 / 1C / PRS 101 / PAO1)]
Length=393
Score = 341 bits (875), Expect = 1e-118
Identities = 178/390 (46%), Positives = 256/390 (66%), Gaps = 2/390 (1%)
Query 1 MTEIVIVNGARTAMGGFQGALAPLTATDLGAVTIKEAIYRSGLQPTDIEEVIMGCVLPAG 60
M ++VIV RTA+G FQG+LA + A +LGA I+ + ++GL ++EVI+G VL AG
Sbjct 1 MQDVVIVAATRTAVGSFQGSLAGIPAPELGAAVIRRLLEQTGLDAGQVDEVILGQVLTAG 60
Query 61 LKQGPARQAMRKAGLPDTTGAVTINKLCGSGMKAVMQAVDMIKAGSAEIVIAGGMESMSN 120
Q PARQA KAGLP A+T+NK+CGSG+KA+ I+ G AE+++AGG E+MS
Sbjct 61 SGQNPARQAAIKAGLPVGVPAMTLNKVCGSGLKALHLGAQAIRCGDAEVIVAGGQENMSL 120
Query 121 APYVLPKARSGYRMGHGEIKDHMFLDGLEDAETGRLMGSFAQDMANTRGYTREQMDDFAI 180
APYV+P AR+G RMGH ++ D M DGL DA MG A+++A G TRE+ D FA
Sbjct 121 APYVMPGARTGLRMGHAKLVDSMIEDGLWDAFNDYHMGITAENLAEKYGLTREEQDAFAA 180
Query 181 RSLKRAQNAITEGYFKAEIVPVTVSSRKGDVI-IEQDEQP-LNAKIDKIPSLKPAFAKDG 238
S ++A AI G F+ EI P+ V RKG+ + + DEQP ++ + LKPAF KDG
Sbjct 181 ASQQKAIAAIEGGRFRDEITPIQVPQRKGEPLGFDTDEQPRAGTTVEALAKLKPAFRKDG 240
Query 239 TITAANSSSISDGASALVLTSIENADQRGLKPLAKVIATASNSQHPSEFTIAPVGAIGKV 298
++TA N+SS++DGA+A++L S A GL LA++ + AS P+ I PV A +
Sbjct 241 SVTAGNASSLNDGAAAVLLMSAAKAKALGLPVLARIASYASAGVDPAIMGIGPVSATRRA 300
Query 299 LKKSGWNAQEVDLWEINEAFAMVTMCAIDDFELDAEKVNIHGGACALGHPVGSTGSRIIL 358
L K+GW+ +++DL E NEAFA ++ + DA +VN++GGA ALGHP+G++G R+++
Sbjct 301 LDKAGWSLEQLDLIEANEAFAAQSLAVGRELGWDAARVNVNGGAIALGHPIGASGCRVLV 360
Query 359 SLIHALQRTGGKKGIAALCIGGGEATAVAI 388
+L+H + R KKG+A LCIGGG+ A+ +
Sbjct 361 TLLHEMIRRDAKKGLATLCIGGGQGVALTL 390
>P44873 Acetyl-CoA acetyltransferase [Haemophilus influenzae (strain
ATCC 51907 / DSM 11121 / KW20 / Rd)]
Length=393
Score = 340 bits (872), Expect = 3e-118
Identities = 183/391 (47%), Positives = 252/391 (64%), Gaps = 2/391 (1%)
Query 1 MTEIVIVNGARTAMGGFQGALAPLTATDLGAVTIKEAIYRSGLQPTDIEEVIMGCVLPAG 60
M +VIV+ RT +G F GAL+ ++A DLGA+ I+EAI R+ ++ + EVIMG VL AG
Sbjct 1 MENVVIVSAVRTPIGSFNGALSSVSAVDLGAIVIQEAIKRANIESALVNEVIMGNVLQAG 60
Query 61 LKQGPARQAMRKAGLPDTTGAVTINKLCGSGMKAVMQAVDMIKAGSAEIVIAGGMESMSN 120
L Q PARQA KAG+ ++TINK+CGSG+K+V I +G A+IV+ GGME+MS
Sbjct 61 LGQNPARQAALKAGIEKEIPSLTINKVCGSGLKSVALGAQSIISGDADIVVVGGMENMSQ 120
Query 121 APYVLP-KARSGYRMGHGEIKDHMFLDGLEDAETGRLMGSFAQDMANTRGYTREQMDDFA 179
APY+L K R G +MG+ ++D M DGL A MG A+++A G +R+ D+ A
Sbjct 121 APYLLDSKVRQGVKMGNLTLRDTMIEDGLTCASNHYHMGITAENIAEQYGISRQAQDELA 180
Query 180 IRSLKRAQNAITEGYFKAEIVPVTVSSRKGDVIIEQDEQP-LNAKIDKIPSLKPAFAKDG 238
+RS A A+ G F EIVPV V +RKGD+I+ +DE P + + + LKPAF K+G
Sbjct 181 LRSQTLASQAVQLGVFDKEIVPVMVKTRKGDIIVSRDEYPKADTTAEGLAKLKPAFKKEG 240
Query 239 TITAANSSSISDGASALVLTSIENADQRGLKPLAKVIATASNSQHPSEFTIAPVGAIGKV 298
T+TA N+S I+DGA+AL+L S A GLK +AK+ + AS PS + PV A K
Sbjct 241 TVTAGNASGINDGAAALILVSESKAHALGLKAIAKIRSYASGGVDPSVMGLGPVPATQKA 300
Query 299 LKKSGWNAQEVDLWEINEAFAMVTMCAIDDFELDAEKVNIHGGACALGHPVGSTGSRIIL 358
LKK+G N ++DL E NEAFA + D LD K NIHGGA ALGHP+G++G+RI++
Sbjct 301 LKKAGINLDDIDLIEANEAFASQFLGVGKDLNLDMNKTNIHGGAIALGHPIGASGARILV 360
Query 359 SLIHALQRTGGKKGIAALCIGGGEATAVAIE 389
+L+H L K G+A LCIGGG+ ++ +E
Sbjct 361 TLLHNLIEKDKKLGLATLCIGGGQGISMIVE 391
>P45363 Acetyl-CoA acetyltransferase [Thiocystis violacea]
Length=394
Score = 338 bits (866), Expect = 2e-117
Identities = 178/388 (46%), Positives = 251/388 (65%), Gaps = 2/388 (1%)
Query 4 IVIVNGARTAMGGFQGALAPLTATDLGAVTIKEAIYRSGLQPTDIEEVIMGCVLPAGLKQ 63
IVIV+ RTA+G F GAL+ L ATD+G +K I R+G+ P + EVI+G VL AG Q
Sbjct 5 IVIVDAGRTAIGTFGGALSALQATDIGTTVLKALIERTGIAPEQVSEVILGQVLTAGCGQ 64
Query 64 GPARQAMRKAGLPDTTGAVTINKLCGSGMKAVMQAVDMIKAGSAEIVIAGGMESMSNAPY 123
PARQ AGLP T A+TINK+CGSG+KAV A+ + G AEIVIAGG ESMS + +
Sbjct 65 NPARQTTLMAGLPHTVPAMTINKVCGSGLKAVHLAMQAVACGDAEIVIAGGQESMSQSSH 124
Query 124 VLPKARSGYRMGHGEIKDHMFLDGLEDAETGRLMGSFAQDMANTRGYTREQMDDFAIRSL 183
VLP++R G RMG +KD M +DGL DA MG A+++A +TRE D FA S
Sbjct 125 VLPRSREGQRMGDWPMKDTMIVDGLWDAFNQCHMGVTAENIAKKYAFTREAQDAFAAASQ 184
Query 184 KRAQNAITEGYFKAEIVPVTVSSRKGD-VIIEQDEQPL-NAKIDKIPSLKPAFAKDGTIT 241
++A+ AI G F EI+PV++ RKGD ++ + DE P + + L+PAF K GT+T
Sbjct 185 QKAEAAIQSGRFADEIIPVSIPQRKGDPLVFDTDEFPRPGTTAETLGRLRPAFDKQGTVT 244
Query 242 AANSSSISDGASALVLTSIENADQRGLKPLAKVIATASNSQHPSEFTIAPVGAIGKVLKK 301
A N+S I+DGA+ +V+ A + GL P+A+++A +S P+ P+ A LKK
Sbjct 245 AGNASGINDGAAMVVVMKESKAKELGLTPMARLVAFSSAGVDPAIMGTGPIPASTDCLKK 304
Query 302 SGWNAQEVDLWEINEAFAMVTMCAIDDFELDAEKVNIHGGACALGHPVGSTGSRIILSLI 361
+GW ++DL E NEAFA M + D KVN++GGA A+GHP+G++G+R++++L+
Sbjct 305 AGWAPADLDLVEANEAFAAQAMSVNQEMGWDLSKVNVNGGAIAIGHPIGASGARVLVTLL 364
Query 362 HALQRTGGKKGIAALCIGGGEATAVAIE 389
+ +Q+ KKG+A LCIGGG+ A+A+E
Sbjct 365 YEMQKRDAKKGLATLCIGGGQGVALAVE 392
>P76461 Acetyl-CoA acetyltransferase [Escherichia coli (strain
K12)]
Length=394
Score = 338 bits (866), Expect = 2e-117
Identities = 185/391 (47%), Positives = 255/391 (65%), Gaps = 2/391 (1%)
Query 1 MTEIVIVNGARTAMGGFQGALAPLTATDLGAVTIKEAIYRSGLQPTDIEEVIMGCVLPAG 60
M VIV+ RTA+G F G+LA +A DLGA IK AI R+ + ++EVIMG VL AG
Sbjct 1 MKNCVIVSAVRTAIGSFNGSLASTSAIDLGATVIKAAIERAKIDSQHVDEVIMGNVLQAG 60
Query 61 LKQGPARQAMRKAGLPDTTGAVTINKLCGSGMKAVMQAVDMIKAGSAEIVIAGGMESMSN 120
L Q PARQA+ K+GL +T T+NK+CGSG+K+V A I+AG A+ ++AGGME+MS
Sbjct 61 LGQNPARQALLKSGLAETVCGFTVNKVCGSGLKSVALAAQAIQAGQAQSIVAGGMENMSL 120
Query 121 APYVLP-KARSGYRMGHGEIKDHMFLDGLEDAETGRLMGSFAQDMANTRGYTREQMDDFA 179
APY+L KARSGYR+G G++ D + DGL A G MG A+++A G TRE D+ A
Sbjct 121 APYLLDAKARSGYRLGDGQVYDVILRDGLMCATHGYHMGITAENVAKEYGITREMQDELA 180
Query 180 IRSLKRAQNAITEGYFKAEIVPVTVSSRKGDVIIEQDEQP-LNAKIDKIPSLKPAFAKDG 238
+ S ++A AI G F AEIVPV V +RK + QDE P N+ + + +L+PAF K G
Sbjct 181 LHSQRKAAAAIESGAFTAEIVPVNVVTRKKTFVFSQDEFPKANSTAEALGALRPAFDKAG 240
Query 239 TITAANSSSISDGASALVLTSIENADQRGLKPLAKVIATASNSQHPSEFTIAPVGAIGKV 298
T+TA N+S I+DGA+ALV+ A GL PLA++ + AS P+ + PV A K
Sbjct 241 TVTAGNASGINDGAAALVIMEESAALAAGLTPLARIKSYASGGVPPALMGMGPVPATQKA 300
Query 299 LKKSGWNAQEVDLWEINEAFAMVTMCAIDDFELDAEKVNIHGGACALGHPVGSTGSRIIL 358
L+ +G ++DL E NEAFA + + D+EKVN++GGA ALGHP+G++G+RI++
Sbjct 301 LQLAGLQLADIDLIEANEAFAAQFLAVGKNLGFDSEKVNVNGGAIALGHPIGASGARILV 360
Query 359 SLIHALQRTGGKKGIAALCIGGGEATAVAIE 389
+L+HA+Q G+A LCIGGG+ A+ IE
Sbjct 361 TLLHAMQARDKTLGLATLCIGGGQGIAMVIE 391
>Q4WCL5 Acetyl-CoA acetyltransferase erg10B, cytosolic [Aspergillus
fumigatus (strain ATCC MYA-4609 / CBS 101355 / FGSC A1100
/ Af293)]
Length=398
Score = 333 bits (854), Expect = 2e-115
Identities = 174/392 (44%), Positives = 255/392 (65%), Gaps = 4/392 (1%)
Query 4 IVIVNGARTAMGGFQGALAPLTATDLGAVTIKEAIYR-SGLQPTDIEEVIMGCVLPAGLK 62
+ IV+ ART +G F G+L+ LTA LGA IK A+ + GL+P+D++EV G V+ A +
Sbjct 7 VYIVSSARTPVGSFLGSLSSLTAPQLGAHAIKAALAKVDGLKPSDVQEVFFGNVISANVG 66
Query 63 QGPARQAMRKAGLPDTTGAVTINKLCGSGMKAVMQAVDMIKAGSAEIVIAGGMESMSNAP 122
Q PARQ AGL ++T T+NK+C SG+KA++ I G+A++V+AGG ESMSNAP
Sbjct 67 QNPARQCALGAGLEESTICTTVNKVCASGLKAIILGAQTIMTGNADVVVAGGTESMSNAP 126
Query 123 YVLPKARSGYRMGHGEIKDHMFLDGLEDAETGRLMGSFAQDMANTRGYTREQMDDFAIRS 182
+ LP R+G + GH + D + DGL DA LMG A++ A G++REQ D++AIR+
Sbjct 127 HYLPNLRTGAKYGHQSLVDGIMKDGLTDAGKQELMGLQAEECAQDHGFSREQQDEYAIRT 186
Query 183 LKRAQNAITEGYFKAEIVPVTVSSRKG--DVIIEQDEQPLNAKIDKIPSLKPAFAK-DGT 239
++AQ A G F EI P+ + +G DV + QDE+P N +K+ ++KPAF GT
Sbjct 187 YEKAQAAQKAGLFDEEIAPIQLPGFRGKPDVTVTQDEEPKNLNPEKLRAIKPAFIPGSGT 246
Query 240 ITAANSSSISDGASALVLTSIENADQRGLKPLAKVIATASNSQHPSEFTIAPVGAIGKVL 299
+TA NSS ++DGA+A+VL S + LKP+AK++ +Q PS+FT AP AI K L
Sbjct 247 VTAPNSSPLNDGAAAVVLVSEAKLKELNLKPVAKILGWGDAAQQPSKFTTAPALAIPKAL 306
Query 300 KKSGWNAQEVDLWEINEAFAMVTMCAIDDFELDAEKVNIHGGACALGHPVGSTGSRIILS 359
K +G +D +EINEAF++V + + + EKVN+HGGA A+GHP+G++G+RI+ +
Sbjct 307 KHAGVGQDAIDAFEINEAFSVVALANMKLLGIPEEKVNLHGGAVAIGHPIGASGARILTT 366
Query 360 LIHALQRTGGKKGIAALCIGGGEATAVAIELI 391
L+ L+ GK G A +C GGG A+A+ +EL+
Sbjct 367 LLGVLKAKKGKLGCAGICNGGGGASALVVELL 398
>B0YA65 Acetyl-CoA acetyltransferase erg10B, cytosolic [Aspergillus
fumigatus (strain CBS 144.89 / FGSC A1163 / CEA10)]
Length=398
Score = 333 bits (854), Expect = 2e-115
Identities = 174/392 (44%), Positives = 255/392 (65%), Gaps = 4/392 (1%)
Query 4 IVIVNGARTAMGGFQGALAPLTATDLGAVTIKEAIYR-SGLQPTDIEEVIMGCVLPAGLK 62
+ IV+ ART +G F G+L+ LTA LGA IK A+ + GL+P+D++EV G V+ A +
Sbjct 7 VYIVSSARTPVGSFLGSLSSLTAPQLGAHAIKAALAKVDGLKPSDVQEVFFGNVISANVG 66
Query 63 QGPARQAMRKAGLPDTTGAVTINKLCGSGMKAVMQAVDMIKAGSAEIVIAGGMESMSNAP 122
Q PARQ AGL ++T T+NK+C SG+KA++ I G+A++V+AGG ESMSNAP
Sbjct 67 QNPARQCALGAGLEESTICTTVNKVCASGLKAIILGAQTIMTGNADVVVAGGTESMSNAP 126
Query 123 YVLPKARSGYRMGHGEIKDHMFLDGLEDAETGRLMGSFAQDMANTRGYTREQMDDFAIRS 182
+ LP R+G + GH + D + DGL DA LMG A++ A G++REQ D++AIR+
Sbjct 127 HYLPNLRTGAKYGHQSLVDGIMKDGLTDAGKQELMGLQAEECAQDHGFSREQQDEYAIRT 186
Query 183 LKRAQNAITEGYFKAEIVPVTVSSRKG--DVIIEQDEQPLNAKIDKIPSLKPAFAK-DGT 239
++AQ A G F EI P+ + +G DV + QDE+P N +K+ ++KPAF GT
Sbjct 187 YEKAQAAQKAGLFDEEIAPIQLPGFRGKPDVTVTQDEEPKNLNPEKLRAIKPAFIPGSGT 246
Query 240 ITAANSSSISDGASALVLTSIENADQRGLKPLAKVIATASNSQHPSEFTIAPVGAIGKVL 299
+TA NSS ++DGA+A+VL S + LKP+AK++ +Q PS+FT AP AI K L
Sbjct 247 VTAPNSSPLNDGAAAVVLVSEAKLKELNLKPVAKILGWGDAAQQPSKFTTAPALAIPKAL 306
Query 300 KKSGWNAQEVDLWEINEAFAMVTMCAIDDFELDAEKVNIHGGACALGHPVGSTGSRIILS 359
K +G +D +EINEAF++V + + + EKVN+HGGA A+GHP+G++G+RI+ +
Sbjct 307 KHAGVGQDAIDAFEINEAFSVVALANMKLLGIPEEKVNLHGGAVAIGHPIGASGARILTT 366
Query 360 LIHALQRTGGKKGIAALCIGGGEATAVAIELI 391
L+ L+ GK G A +C GGG A+A+ +EL+
Sbjct 367 LLGVLKAKKGKLGCAGICNGGGGASALVVELL 398
>Q04677 Acetyl-CoA acetyltransferase IB [Candida tropicalis]
Length=403
Score = 332 bits (850), Expect = 8e-115
Identities = 178/392 (45%), Positives = 255/392 (65%), Gaps = 4/392 (1%)
Query 4 IVIVNGARTAMGGFQGALAPLTATDLGAVTIKEAIYR-SGLQPTDIEEVIMGCVLPAGLK 62
+ IV+ ART +G FQG+L+ LT +DLGA +K A+ + ++P D++E++ G VL A +
Sbjct 6 VYIVSTARTPIGSFQGSLSSLTYSDLGAHAVKAALAKVPQIKPQDVDEIVFGGVLQANVG 65
Query 63 QGPARQAMRKAGLPDTTGAVTINKLCGSGMKAVMQAVDMIKAGSAEIVIAGGMESMSNAP 122
Q PARQ KAGLPD+ A TINK+C SGMKAV+ I G+++IV+ GG ESMSN P
Sbjct 66 QAPARQVALKAGLPDSIIASTINKVCASGMKAVIIGAQNIICGTSDIVVVGGAESMSNTP 125
Query 123 YVLPKARSGYRMGHGEIKDHMFLDGLEDAETGRLMGSFAQDMANTRGYTREQMDDFAIRS 182
Y LP ARSG R G + D + DGL D +LMG A+ A G++RE D+FAI S
Sbjct 126 YYLPSARSGARYGDAVMVDGVQKDGLLDVYEEKLMGVAAEKCAKDHGFSREDQDNFAINS 185
Query 183 LKRAQNAITEGYFKAEIVPVTVSSRKG--DVIIEQDEQPLNAKIDKIPSLKPAFAKD-GT 239
K+A A++EG FK+EI PVT+ +G D +IE DE+ D++ S + F K+ GT
Sbjct 186 YKKAGKALSEGKFKSEIAPVTIKGFRGKPDTVIENDEEIGKFNEDRLKSARTVFQKENGT 245
Query 240 ITAANSSSISDGASALVLTSIENADQRGLKPLAKVIATASNSQHPSEFTIAPVGAIGKVL 299
+TA N+S ++DG +ALVL S Q GLKPLAK+ ++ P +FTIAP A+ K +
Sbjct 246 VTAPNASKLNDGGAALVLVSEAKLKQLGLKPLAKISGWGEAARTPFDFTIAPALAVPKAV 305
Query 300 KKSGWNAQEVDLWEINEAFAMVTMCAIDDFELDAEKVNIHGGACALGHPVGSTGSRIILS 359
K +G VD +E+NEAF++V + + ++ EK+N++GGA A+GHP+G +G+RII++
Sbjct 306 KHAGLTVDRVDFFELNEAFSVVGLANAELVKIPLEKLNVYGGAVAMGHPLGCSGARIIVT 365
Query 360 LIHALQRTGGKKGIAALCIGGGEATAVAIELI 391
L+ L + GG+ G A +C GGG A+A+ IE I
Sbjct 366 LLSVLTQEGGRFGAAGVCNGGGGASAIVIEKI 397
>Q12598 Acetyl-CoA acetyltransferase IA [Candida tropicalis]
Length=403
Score = 332 bits (850), Expect = 8e-115
Identities = 178/392 (45%), Positives = 255/392 (65%), Gaps = 4/392 (1%)
Query 4 IVIVNGARTAMGGFQGALAPLTATDLGAVTIKEAIYR-SGLQPTDIEEVIMGCVLPAGLK 62
+ IV+ ART +G FQG+L+ LT +DLGA +K A+ + ++P D++E++ G VL A +
Sbjct 6 VYIVSTARTPIGSFQGSLSSLTYSDLGAHAVKAALAKVPQIKPQDVDEIVFGGVLQANVG 65
Query 63 QGPARQAMRKAGLPDTTGAVTINKLCGSGMKAVMQAVDMIKAGSAEIVIAGGMESMSNAP 122
Q PARQ KAGLPD+ A TINK+C SGMKAV+ I G+++IV+ GG ESMSN P
Sbjct 66 QAPARQVALKAGLPDSIVASTINKVCASGMKAVIIGAQNIICGTSDIVVVGGAESMSNTP 125
Query 123 YVLPKARSGYRMGHGEIKDHMFLDGLEDAETGRLMGSFAQDMANTRGYTREQMDDFAIRS 182
Y LP ARSG R G + D + DGL D +LMG A+ A G++RE D+FAI S
Sbjct 126 YYLPSARSGARYGDAIMVDGVQKDGLLDVYEEKLMGVAAEKCAKDHGFSREDQDNFAINS 185
Query 183 LKRAQNAITEGYFKAEIVPVTVSSRKG--DVIIEQDEQPLNAKIDKIPSLKPAFAKD-GT 239
K+A A++EG FK+EI PVT+ +G D +IE DE+ +++ S + F K+ GT
Sbjct 186 YKKAGKALSEGKFKSEIAPVTIKGFRGKPDTVIENDEEIGKFNEERLKSARTVFQKENGT 245
Query 240 ITAANSSSISDGASALVLTSIENADQRGLKPLAKVIATASNSQHPSEFTIAPVGAIGKVL 299
+TA N+S ++DG +ALVL S Q GLKPLAK+ ++ P +FTIAP A+ K +
Sbjct 246 VTAPNASKLNDGGAALVLVSEAKLKQLGLKPLAKISGWGEAARTPFDFTIAPALAVPKAV 305
Query 300 KKSGWNAQEVDLWEINEAFAMVTMCAIDDFELDAEKVNIHGGACALGHPVGSTGSRIILS 359
K +G VD +E+NEAF++V + + + EK+N++GGA A+GHP+G +G+RII++
Sbjct 306 KHAGLTVDRVDFFELNEAFSVVGLANAELVNIPLEKLNVYGGAVAMGHPLGCSGARIIVT 365
Query 360 LIHALQRTGGKKGIAALCIGGGEATAVAIELI 391
L+ L + GG+ G+A +C GGG A+AV IE I
Sbjct 366 LLSVLTQEGGRFGVAGVCNGGGGASAVVIEKI 397
>Q9BWD1 Acetyl-CoA acetyltransferase, cytosolic [Homo sapiens]
Length=397
Score = 325 bits (833), Expect = 3e-112
Identities = 176/389 (45%), Positives = 251/389 (65%), Gaps = 4/389 (1%)
Query 4 IVIVNGARTAMGGFQGALAPLTATDLGAVTIKEAIYRSGLQPTDIEEVIMGCVLPAGLKQ 63
+VIV+ ART +G F GALA + DLG+ IKE + R+ + P D+ EVI G VL AG Q
Sbjct 8 VVIVSAARTIIGSFNGALAAVPVQDLGSTVIKEVLKRATVAPEDVSEVIFGHVLAAGCGQ 67
Query 64 GPARQAMRKAGLPDTTGAVTINKLCGSGMKAVMQAVDMIKAGSAEIVIAGGMESMSNAPY 123
P RQA AG+P + A + +CGSG+KAV AV I G + IV+AGGME+MS AP+
Sbjct 68 NPVRQASVGAGIPYSVPAWSCQMICGSGLKAVCLAVQSIGIGDSSIVVAGGMENMSKAPH 127
Query 124 VLPKARSGYRMGHGEIKDHMFLDGLEDAETGRLMGSFAQDMANTRGYTREQMDDFAIRSL 183
L R+G ++G + D + DGL DA MG A+++A +RE D A+ S
Sbjct 128 -LAYLRTGVKIGEMPLTDSILCDGLTDAFHNCHMGITAENVAKKWQVSREDQDKVAVLSQ 186
Query 184 KRAQNAITEGYFKAEIVPVTVSSRKGDVIIEQDEQPLN-AKIDKIPSLKPAFAKDGT--I 240
R +NA G+F EIVPV VS+RKG + ++ DE P + + I+ + LKP F DGT +
Sbjct 187 NRTENAQKAGHFDKEIVPVLVSTRKGLIEVKTDEFPRHGSNIEAMSKLKPYFLTDGTGTV 246
Query 241 TAANSSSISDGASALVLTSIENADQRGLKPLAKVIATASNSQHPSEFTIAPVGAIGKVLK 300
T AN+S I+DGA+A+VL AD+RGL PLA++++ + PS I P+ AI + +
Sbjct 247 TPANASGINDGAAAVVLMKKSEADKRGLTPLARIVSWSQVGVEPSIMGIGPIPAIKQAVT 306
Query 301 KSGWNAQEVDLWEINEAFAMVTMCAIDDFELDAEKVNIHGGACALGHPVGSTGSRIILSL 360
K+GW+ ++VD++EINEAFA V+ + + L+ EKVNI GGA ALGHP+G++G RI+++L
Sbjct 307 KAGWSLEDVDIFEINEAFAAVSAAIVKELGLNPEKVNIEGGAIALGHPLGASGCRILVTL 366
Query 361 IHALQRTGGKKGIAALCIGGGEATAVAIE 389
+H L+R G +G+AALCIGGG A+ ++
Sbjct 367 LHTLERMGRSRGVAALCIGGGMGIAMCVQ 395
Lambda K H a alpha
0.318 0.133 0.378 0.792 4.96
Gapped
Lambda K H a alpha sigma
0.267 0.0410 0.140 1.90 42.6 43.6
Effective search space used: 1783600
Database: 593b982b1e5663d3b5a34f1ff897f3ee.SwissProt.fasta
Posted date: May 9, 2024 7:27 PM
Number of letters in database: 5,935
Number of sequences in database: 15
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Neighboring words threshold: 11
Window for multiple hits: 40
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Data ...
