BLASTP 2.12.0+
Reference: Stephen F. Altschul, Thomas L. Madden, Alejandro A.
Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J.
Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of
protein database search programs", Nucleic Acids Res. 25:3389-3402.
Reference for composition-based statistics: Alejandro A. Schaffer,
L. Aravind, Thomas L. Madden, Sergei Shavirin, John L. Spouge, Yuri
I. Wolf, Eugene V. Koonin, and Stephen F. Altschul (2001),
"Improving the accuracy of PSI-BLAST protein database searches with
composition-based statistics and other refinements", Nucleic Acids
Res. 29:2994-3005.
Database: 17d580adec08f25d1c897b04bda9368f.SwissProt.fasta
21 sequences; 4,804 total letters
Query= ACIAD0859
Length=214
Score E
Sequences producing significant alignments: (Bits) Value
Q9JV95 ATP-dependent dethiobiotin synthetase BioD [Neisseria meni... 240 3e-84
Q9K085 ATP-dependent dethiobiotin synthetase BioD [Neisseria meni... 236 6e-83
A9M388 ATP-dependent dethiobiotin synthetase BioD [Neisseria meni... 235 2e-82
A1KSZ5 ATP-dependent dethiobiotin synthetase BioD [Neisseria meni... 234 5e-82
B4RJZ8 ATP-dependent dethiobiotin synthetase BioD [Neisseria gono... 234 7e-82
Q5F9T1 ATP-dependent dethiobiotin synthetase BioD [Neisseria gono... 234 7e-82
Q9CJT7 ATP-dependent dethiobiotin synthetase BioD 2 [Pasteurella ... 202 1e-69
Q7VL12 ATP-dependent dethiobiotin synthetase BioD 2 [Haemophilus ... 191 3e-65
P45248 ATP-dependent dethiobiotin synthetase BioD 2 [Haemophilus ... 181 3e-61
Q8KGC0 ATP-dependent dethiobiotin synthetase BioD [Chlorobaculum ... 181 6e-61
B5YHS9 ATP-dependent dethiobiotin synthetase BioD [Thermodesulfov... 112 4e-34
P22818 ATP-dependent dethiobiotin synthetase BioD [Lysinibacillus... 108 2e-32
P36572 ATP-dependent dethiobiotin synthetase BioD [Serratia marce... 95.9 9e-28
P13000 ATP-dependent dethiobiotin synthetase BioD 1 [Escherichia ... 94.0 5e-27
P46397 ATP-dependent dethiobiotin synthetase BioD [Corynebacteriu... 86.3 4e-24
O06899 ATP-dependent dethiobiotin synthetase BioD [Pseudescherich... 85.9 7e-24
P53558 ATP-dependent dethiobiotin synthetase BioD [Bacillus subti... 84.0 3e-23
O24872 ATP-dependent dethiobiotin synthetase BioD [Helicobacter p... 75.9 3e-20
P53630 Dethiobiotin synthetase [Saccharomyces cerevisiae (strain ... 58.9 5e-14
P9WPQ5 Dethiobiotin synthetase BioD [Mycobacterium tuberculosis (... 56.6 3e-13
Q52312 Protein IncC [Escherichia coli] 36.6 3e-06
>Q9JV95 ATP-dependent dethiobiotin synthetase BioD [Neisseria
meningitidis serogroup A / serotype 4A (strain DSM 15465 / Z2491)]
Length=215
Score = 240 bits (612), Expect = 3e-84
Identities = 119/208 (57%), Positives = 156/208 (75%), Gaps = 0/208 (0%)
Query 5 VYFISGIDTGIGKTYATGYLAKQWIDQGIKTITQKLIQTGNIEISEDIEKHRDIMQTGFL 64
VYF+SGIDT IGKT ATG LAKQ + QG ITQK +QTG I++DI HR IM
Sbjct 4 VYFVSGIDTDIGKTIATGVLAKQLLQQGKSVITQKPVQTGCQNIADDIAVHRKIMGIPMQ 63
Query 65 PEDDEKLTMPEIFTYPASPHLATKMDGRALDFNKIEQATHILKQRFDVVLLEGAGGLMVP 124
D + LTMPEIF+YPASPHLA ++DGRALD +KI AT L ++++VL+EGAGGLMVP
Sbjct 64 EADKQGLTMPEIFSYPASPHLAARLDGRALDLDKIRTATQQLAAQYEIVLVEGAGGLMVP 123
Query 125 LTTDMLTIDYIAEHQFPIILVSSGRLGSINHTLLSLEAIKQRGLSLYALAYNLNDESQDT 184
LT ++LTIDYI + +P+IL++SGRLGSINHTLLS A+KQ G+ L++L +N +S+D
Sbjct 124 LTENLLTIDYIRQQGYPVILITSGRLGSINHTLLSFAALKQYGIRLHSLVFNHIHDSRDA 183
Query 185 IISKDTAQYLKQYLKHSFPEAKWIDIPK 212
+++D+ YLK LK SFPEA+W+++ K
Sbjct 184 HVAQDSLNYLKCRLKDSFPEAEWLELAK 211
>Q9K085 ATP-dependent dethiobiotin synthetase BioD [Neisseria
meningitidis serogroup B (strain MC58)]
Length=215
Score = 236 bits (603), Expect = 6e-83
Identities = 120/208 (58%), Positives = 154/208 (74%), Gaps = 0/208 (0%)
Query 5 VYFISGIDTGIGKTYATGYLAKQWIDQGIKTITQKLIQTGNIEISEDIEKHRDIMQTGFL 64
VYF+SGIDT IGKT ATG LAKQ + QG ITQK +QTG I++DI HR IM
Sbjct 4 VYFVSGIDTDIGKTVATGVLAKQLLQQGKSVITQKPVQTGCQNIADDIAVHRKIMGIPMQ 63
Query 65 PEDDEKLTMPEIFTYPASPHLATKMDGRALDFNKIEQATHILKQRFDVVLLEGAGGLMVP 124
D +LTMPEIF+YPASPHLA ++DGRALD +KI AT L +++VVL+EGAGGLMVP
Sbjct 64 EADKRRLTMPEIFSYPASPHLAARLDGRALDLDKIRTATQELAAQYEVVLVEGAGGLMVP 123
Query 125 LTTDMLTIDYIAEHQFPIILVSSGRLGSINHTLLSLEAIKQRGLSLYALAYNLNDESQDT 184
LT ++LTIDYI + +P+ILV+SGRLGSINHTLLS A+KQ G+ L++L +N +S+D
Sbjct 124 LTENLLTIDYIRQQGYPVILVTSGRLGSINHTLLSFAALKQYGIRLHSLVFNHIHDSRDA 183
Query 185 IISKDTAQYLKQYLKHSFPEAKWIDIPK 212
I++D+ YLK LK F EA+W+++ K
Sbjct 184 HIAQDSLSYLKCRLKADFSEAEWMELAK 211
>A9M388 ATP-dependent dethiobiotin synthetase BioD [Neisseria
meningitidis serogroup C (strain 053442)]
Length=215
Score = 235 bits (600), Expect = 2e-82
Identities = 119/208 (57%), Positives = 154/208 (74%), Gaps = 0/208 (0%)
Query 5 VYFISGIDTGIGKTYATGYLAKQWIDQGIKTITQKLIQTGNIEISEDIEKHRDIMQTGFL 64
VYF+SGIDT IGKT ATG LAKQ + QG ITQK +QTG I++DI HR IM
Sbjct 4 VYFVSGIDTDIGKTVATGVLAKQLLQQGKSVITQKPVQTGCQNIADDIAVHRKIMGKPMQ 63
Query 65 PEDDEKLTMPEIFTYPASPHLATKMDGRALDFNKIEQATHILKQRFDVVLLEGAGGLMVP 124
D + LTMPEIF+YPASPHLA ++DGRALD +KI AT L ++++VL+EGAGGLMVP
Sbjct 64 EADKQGLTMPEIFSYPASPHLAARLDGRALDLDKIRTATQQLAAQYEIVLVEGAGGLMVP 123
Query 125 LTTDMLTIDYIAEHQFPIILVSSGRLGSINHTLLSLEAIKQRGLSLYALAYNLNDESQDT 184
LT ++LTIDYI + +P+ILV+SGRLGSINHTLLS A+KQ G+ L++L +N +S+D
Sbjct 124 LTENLLTIDYIRQQGYPVILVTSGRLGSINHTLLSFAALKQYGIRLHSLVFNHIHDSRDA 183
Query 185 IISKDTAQYLKQYLKHSFPEAKWIDIPK 212
I++D+ YLK LK F EA+W+++ K
Sbjct 184 HIAQDSLNYLKCRLKADFSEAEWMELAK 211
>A1KSZ5 ATP-dependent dethiobiotin synthetase BioD [Neisseria
meningitidis serogroup C / serotype 2a (strain ATCC 700532 /
DSM 15464 / FAM18)]
Length=215
Score = 234 bits (597), Expect = 5e-82
Identities = 119/208 (57%), Positives = 153/208 (74%), Gaps = 0/208 (0%)
Query 5 VYFISGIDTGIGKTYATGYLAKQWIDQGIKTITQKLIQTGNIEISEDIEKHRDIMQTGFL 64
VYF+SGIDT IGKT ATG LAKQ + QG ITQK +QTG +I+EDI HR IM
Sbjct 4 VYFVSGIDTDIGKTVATGMLAKQLLQQGKSVITQKPVQTGCQDIAEDIAVHRKIMGIPMQ 63
Query 65 PEDDEKLTMPEIFTYPASPHLATKMDGRALDFNKIEQATHILKQRFDVVLLEGAGGLMVP 124
D +LTMPEIF+YPASPHLA ++DGRALD +KI AT L ++++VL+EGAGGLMVP
Sbjct 64 EADKRRLTMPEIFSYPASPHLAARLDGRALDLDKIRTATQELAAQYEIVLVEGAGGLMVP 123
Query 125 LTTDMLTIDYIAEHQFPIILVSSGRLGSINHTLLSLEAIKQRGLSLYALAYNLNDESQDT 184
LT +LTIDYI + +P+ILV+SGRLGSINHTLLS A+KQ G+ L++L +N +S+D
Sbjct 124 LTEKLLTIDYIQQQAYPVILVTSGRLGSINHTLLSFAALKQYGIRLHSLVFNHIHDSRDA 183
Query 185 IISKDTAQYLKQYLKHSFPEAKWIDIPK 212
I++ + YLK LK F EA+W+++ K
Sbjct 184 HIAQYSLSYLKCRLKADFSEAEWMELAK 211
>B4RJZ8 ATP-dependent dethiobiotin synthetase BioD [Neisseria
gonorrhoeae (strain NCCP11945)]
Length=215
Score = 234 bits (596), Expect = 7e-82
Identities = 116/208 (56%), Positives = 155/208 (75%), Gaps = 0/208 (0%)
Query 5 VYFISGIDTGIGKTYATGYLAKQWIDQGIKTITQKLIQTGNIEISEDIEKHRDIMQTGFL 64
VYF+SGIDT IGKT ATG LAKQ + QG ITQK +QTG +I+EDI HR IM
Sbjct 4 VYFVSGIDTDIGKTVATGMLAKQLLQQGKSVITQKPVQTGCQDIAEDIAVHRKIMGIPMQ 63
Query 65 PEDDEKLTMPEIFTYPASPHLATKMDGRALDFNKIEQATHILKQRFDVVLLEGAGGLMVP 124
D+++LTMPEIF++PASPHLA ++DGR LD +KI AT L +++VVL+EGAGGLMVP
Sbjct 64 EADEQRLTMPEIFSHPASPHLAARLDGRGLDLDKIRTATQELAAQYEVVLVEGAGGLMVP 123
Query 125 LTTDMLTIDYIAEHQFPIILVSSGRLGSINHTLLSLEAIKQRGLSLYALAYNLNDESQDT 184
LT +LTID+I + +P+ILV+SGRLGSINHTLLS +KQ G+ L++L +N +S+D
Sbjct 124 LTEKLLTIDHIQQQAYPVILVTSGRLGSINHTLLSFVVLKQYGIRLHSLVFNHIHDSRDA 183
Query 185 IISKDTAQYLKQYLKHSFPEAKWIDIPK 212
+++D+ YL+ LK FPEA+W+++ K
Sbjct 184 HVAQDSLNYLQCRLKADFPEAEWMELAK 211
>Q5F9T1 ATP-dependent dethiobiotin synthetase BioD [Neisseria
gonorrhoeae (strain ATCC 700825 / FA 1090)]
Length=215
Score = 234 bits (596), Expect = 7e-82
Identities = 116/208 (56%), Positives = 155/208 (75%), Gaps = 0/208 (0%)
Query 5 VYFISGIDTGIGKTYATGYLAKQWIDQGIKTITQKLIQTGNIEISEDIEKHRDIMQTGFL 64
VYF+SGIDT IGKT ATG LAKQ + QG ITQK +QTG +I+EDI HR IM
Sbjct 4 VYFVSGIDTDIGKTVATGMLAKQLLQQGKSVITQKPVQTGCQDIAEDIAVHRKIMGIPMQ 63
Query 65 PEDDEKLTMPEIFTYPASPHLATKMDGRALDFNKIEQATHILKQRFDVVLLEGAGGLMVP 124
D+++LTMPEIF++PASPHLA ++DGR LD +KI AT L +++VVL+EGAGGLMVP
Sbjct 64 EADEQRLTMPEIFSHPASPHLAARLDGRGLDLDKIRTATQELAAQYEVVLVEGAGGLMVP 123
Query 125 LTTDMLTIDYIAEHQFPIILVSSGRLGSINHTLLSLEAIKQRGLSLYALAYNLNDESQDT 184
LT +LTID+I + +P+ILV+SGRLGSINHTLLS +KQ G+ L++L +N +S+D
Sbjct 124 LTEKLLTIDHIQQQAYPVILVTSGRLGSINHTLLSFVVLKQYGIRLHSLVFNHIHDSRDA 183
Query 185 IISKDTAQYLKQYLKHSFPEAKWIDIPK 212
+++D+ YL+ LK FPEA+W+++ K
Sbjct 184 HVAQDSLNYLQCRLKADFPEAEWMELAK 211
>Q9CJT7 ATP-dependent dethiobiotin synthetase BioD 2 [Pasteurella
multocida (strain Pm70)]
Length=213
Score = 202 bits (515), Expect = 1e-69
Identities = 100/201 (50%), Positives = 142/201 (71%), Gaps = 1/201 (0%)
Query 3 ASVYFISGIDTGIGKTYATGYLAKQWIDQGIKTITQKLIQTGNIEISEDIEKHRDIMQTG 62
A V+FI+GIDT IGKT ATG+ AK+ + QG ITQK+IQTG I+ED+ HR I
Sbjct 2 AKVFFITGIDTDIGKTIATGWYAKKLMQQGASVITQKMIQTGCRGIAEDLLTHRKIQGIE 61
Query 63 FLPEDDEKLTMPEIFTYPASPHLATKMDGRALDFNKIEQATHILKQRFDVVLLEGAGGLM 122
ED + +T P +F YP SPHLA K++ R ++ KIE T +L +++D VLLEGAGGL
Sbjct 62 LTEEDKQGITCPYVFDYPCSPHLAAKLEQRTIERKKIETCTALLCEKYDYVLLEGAGGLC 121
Query 123 VPLTTDMLTIDYIAEHQFPIILVSSGRLGSINHTLLSLEAIKQRGLSLYALAYNLNDESQ 182
VP + T+DY+ +HQ+P+ILV+SG+LGSINHTLLSL+ + + +S++A+ YNL E+
Sbjct 122 VPYNEEETTLDYLCQHQYPVILVTSGKLGSINHTLLSLQVLNSKRVSVHAVIYNLYPET- 180
Query 183 DTIISKDTAQYLKQYLKHSFP 203
D +IS++T +L++YL+ P
Sbjct 181 DQVISQETQHFLRRYLEKYSP 201
>Q7VL12 ATP-dependent dethiobiotin synthetase BioD 2 [Haemophilus
ducreyi (strain 35000HP / ATCC 700724)]
Length=211
Score = 191 bits (486), Expect = 3e-65
Identities = 100/204 (49%), Positives = 133/204 (65%), Gaps = 1/204 (0%)
Query 5 VYFISGIDTGIGKTYATGYLAKQWIDQGIKTITQKLIQTGNIEISEDIEKHRDIMQTGFL 64
+ F+SGIDT IGKT ATG+ AK+ + QG ITQK+IQTG IS DI KHR +
Sbjct 4 IIFVSGIDTDIGKTIATGFYAKRLMQQGFSVITQKMIQTGCQHISADIIKHRQLQGIELT 63
Query 65 PEDDEKLTMPEIFTYPASPHLATKMDGRALDFNKIEQATHILKQRFDVVLLEGAGGLMVP 124
ED +T P +F YP SPHLA +M+ + +KI QA+ +L Q++D VLLEGAGGL VP
Sbjct 64 AEDLNGITCPYLFRYPCSPHLAAEMENNPILPSKIAQASALLAQKYDYVLLEGAGGLAVP 123
Query 125 LTTDMLTIDYIAEHQFPIILVSSGRLGSINHTLLSLEAIKQRGLSLYALAYNLNDESQDT 184
+ T+DYI E Q P+ILV+S +LGSINHTLLSL +Q + + A+ YN +D
Sbjct 124 YNSQQTTLDYIVEQQLPLILVTSAKLGSINHTLLSLIVCQQHKIEMEAVIYN-TYPLEDE 182
Query 185 IISKDTAQYLKQYLKHSFPEAKWI 208
I+K T YL+QY+K FP +++
Sbjct 183 KIAKSTQLYLQQYIKQHFPNTEFL 206
>P45248 ATP-dependent dethiobiotin synthetase BioD 2 [Haemophilus
influenzae (strain ATCC 51907 / DSM 11121 / KW20 / Rd)]
Length=191
Score = 181 bits (458), Expect = 3e-61
Identities = 93/187 (50%), Positives = 126/187 (67%), Gaps = 0/187 (0%)
Query 5 VYFISGIDTGIGKTYATGYLAKQWIDQGIKTITQKLIQTGNIEISEDIEKHRDIMQTGFL 64
V FISGIDT +GKT ATG AK+ ++QG ITQK+IQTG I++D+ HR I
Sbjct 4 VIFISGIDTDVGKTIATGIYAKKLMEQGCSVITQKMIQTGCKNIADDLLVHRKIQGIDLT 63
Query 65 PEDDEKLTMPEIFTYPASPHLATKMDGRALDFNKIEQATHILKQRFDVVLLEGAGGLMVP 124
ED + T P +F YP SPHLA K + R ++ IE++T +L +++D VLLEGAGGLMVP
Sbjct 64 EEDLQGKTCPYVFEYPCSPHLAAKRESRKIEAKIIEKSTALLAEKYDYVLLEGAGGLMVP 123
Query 125 LTTDMLTIDYIAEHQFPIILVSSGRLGSINHTLLSLEAIKQRGLSLYALAYNLNDESQDT 184
+ T+DYI + +P+ILV+SG+LGSINHTLLSLEA + RG+S+ ++ YN E
Sbjct 124 YCEEATTLDYIQLNNYPLILVTSGKLGSINHTLLSLEACRTRGISVLSVMYNGYPEYDLL 183
Query 185 IISKDTA 191
++ K A
Sbjct 184 LVKKPNA 190
>Q8KGC0 ATP-dependent dethiobiotin synthetase BioD [Chlorobaculum
tepidum (strain ATCC 49652 / DSM 12025 / NBRC 103806 / TLS)]
Length=239
Score = 181 bits (460), Expect = 6e-61
Identities = 96/210 (46%), Positives = 135/210 (64%), Gaps = 0/210 (0%)
Query 1 MTASVYFISGIDTGIGKTYATGYLAKQWIDQGIKTITQKLIQTGNIEISEDIEKHRDIMQ 60
M V ISGIDTGIGKT TG LA+ + + G +TITQK+ QTG +SEDI +HR +M
Sbjct 9 MKGQVLAISGIDTGIGKTVVTGLLARCFAETGWRTITQKIAQTGCEGVSEDIAEHRKLMG 68
Query 61 TGFLPEDDEKLTMPEIFTYPASPHLATKMDGRALDFNKIEQATHILKQRFDVVLLEGAGG 120
D + T P +F +PASPHLA ++GR +DF I ++T L++ +D+VLLEG GG
Sbjct 69 IDLQEADLDGTTCPYLFRFPASPHLAATVEGREIDFMTIRRSTFRLQKLYDLVLLEGVGG 128
Query 121 LMVPLTTDMLTIDYIAEHQFPIILVSSGRLGSINHTLLSLEAIKQRGLSLYALAYNLNDE 180
L+VPLT ++L DY+ + + ++LVS+ RLGSINHTLLSLEA +RG+ + A+ YN E
Sbjct 129 LLVPLTPELLFADYVRDAGYGLVLVSASRLGSINHTLLSLEACARRGIPVRAIVYNRYFE 188
Query 181 SQDTIISKDTAQYLKQYLKHSFPEAKWIDI 210
+ + I + ++ F EA ID+
Sbjct 189 ADERIAANTREVIAAALKRYGFGEAPVIDL 218
>B5YHS9 ATP-dependent dethiobiotin synthetase BioD [Thermodesulfovibrio
yellowstonii (strain ATCC 51303 / DSM 11347 / YP87)]
Length=240
Score = 112 bits (281), Expect = 4e-34
Identities = 69/203 (34%), Positives = 111/203 (55%), Gaps = 16/203 (8%)
Query 6 YFISGIDTGIGKTYATGYLAKQWIDQGIKTITQKLIQTG-----NIEISEDIEKHRDIMQ 60
YFI+G DTG+GKT T + + +I +G+K K+I+TG I + D RD+ +
Sbjct 5 YFITGTDTGVGKTIVTSAILRSFIKKGLKVGAMKVIETGCLNKDGILLPSDGMLLRDMAE 64
Query 61 TGFLPEDDEKLTMPEIFTYPASPHLATKMDGRALDFNKIEQATHILKQRFDVVLLEGAGG 120
D L P P SP +A++++ +D +I +A L++++D +L+EG GG
Sbjct 65 MN----DSLDLITPIKLENPLSPLVASRIEEIEVDIERIFRAFETLQKKYDYLLVEGVGG 120
Query 121 LMVPLTTD-------MLTIDYIAEHQFPIILVSSGRLGSINHTLLSLEAIKQRGLSLYAL 173
LMVPL + D I + P+ILV+ LG+INHTLL+LEA+K + +S+
Sbjct 121 LMVPLNKEEKKKSMFYFVRDLIKDMGLPVILVTRPTLGTINHTLLTLEALKNKKISVKGY 180
Query 174 AYNLNDESQDTIISKDTAQYLKQ 196
N ++ +++ I K Q LK+
Sbjct 181 IINFSEPAKNDIAEKTNPQVLKE 203
>P22818 ATP-dependent dethiobiotin synthetase BioD [Lysinibacillus
sphaericus]
Length=234
Score = 108 bits (269), Expect = 2e-32
Identities = 69/212 (33%), Positives = 116/212 (55%), Gaps = 13/212 (6%)
Query 6 YFISGIDTGIGKTYATGYLAKQWIDQGIKTITQKLIQTGNIEISEDIEKHRDIMQTGFLP 65
+++ G DT +GKT+ T L + QG++ K +QTG + E M +
Sbjct 4 FWVVGTDTDVGKTFVTTLLMRNLQKQGVRVTPYKPVQTGEVYDGEQAYYFDTAMYEKYSL 63
Query 66 E--DDEKLTMPEIFTYPASPHLATKMDGRALDFNKIEQATHILKQRFDVVLLEGAGGLMV 123
+ D E L F ASPH A +++G+ +D ++ + +L+Q +DVV+ EGAGGL V
Sbjct 64 QLLDRENLNGYS-FKEAASPHFAAQLEGQQIDTQQLLKQMQLLQQTWDVVICEGAGGLFV 122
Query 124 PLTT--DMLTIDYIAEHQFPIILVSSGRLGSINHTLLSLEAIKQRGLSLYALAYNLNDES 181
PL + +D I E + P+++V+ LG+INHTLL+LEA+ R + + L +N + S
Sbjct 123 PLDACGETTLLDVIVESKLPVVVVTRTALGTINHTLLTLEALTTRKIEVLGLVFNGDMGS 182
Query 182 QDTIISKDTAQYLKQYLKHSFPEAKWIDIPKI 213
+ + +D Q + QY ++ P ++ IPK+
Sbjct 183 R---MEQDNIQTILQY--YTLP---YMTIPKL 206
>P36572 ATP-dependent dethiobiotin synthetase BioD [Serratia marcescens]
Length=227
Score = 95.9 bits (237), Expect = 9e-28
Identities = 54/168 (32%), Positives = 92/168 (55%), Gaps = 5/168 (3%)
Query 6 YFISGIDTGIGKTYATGYLAKQWIDQGIKTITQKLIQTGNIEISEDIEKHRDIM---QTG 62
+F++G DT +GK+ A+ L + G + K + +G+ +E + + +G
Sbjct 5 WFVTGTDTEVGKSVASSALLQAANRAGYPSAGYKPVASGSEMTAEGLRNGDALALQANSG 64
Query 63 FLPEDDEKLTMPEIFTYPASPHLATKMDGRALDFNKIEQATHILKQRFDVVLLEGAGGLM 122
+ DE P +F P SPH+ + +GR +D ++ L+QR D VL+EGAGG
Sbjct 65 VALDYDE--VNPYVFAEPTSPHIVSADEGRPIDAARLSDGLRRLEQRADWVLVEGAGGWF 122
Query 123 VPLTTDMLTIDYIAEHQFPIILVSSGRLGSINHTLLSLEAIKQRGLSL 170
PL+ + D++ + Q P+ILV +LG INH +L+ +A++Q GL+L
Sbjct 123 TPLSAEYTFADWVRQEQLPVILVVGIKLGCINHAVLTAQAVQQAGLTL 170
>P13000 ATP-dependent dethiobiotin synthetase BioD 1 [Escherichia
coli (strain K12)]
Length=225
Score = 94.0 bits (232), Expect = 5e-27
Identities = 53/166 (32%), Positives = 87/166 (52%), Gaps = 1/166 (1%)
Query 6 YFISGIDTGIGKTYATGYLAKQWIDQGIKTITQKLIQTGNIEISEDIEKHRDI-MQTGFL 64
YF++G DT +GKT A+ L + G +T K + +G+ + E + + +Q
Sbjct 5 YFVTGTDTEVGKTVASCALLQAAKAAGYRTAGYKPVASGSEKTPEGLRNSDALALQRNSS 64
Query 65 PEDDEKLTMPEIFTYPASPHLATKMDGRALDFNKIEQATHILKQRFDVVLLEGAGGLMVP 124
+ D P F P SPH+ + +GR ++ + L+Q+ D VL+EGAGG P
Sbjct 65 LQLDYATVNPYTFAEPTSPHIISAQEGRPIESLVMSAGLRALEQQADWVLVEGAGGWFTP 124
Query 125 LTTDMLTIDYIAEHQFPIILVSSGRLGSINHTLLSLEAIKQRGLSL 170
L+ D++ + Q P+ILV +LG INH +L+ + I+ GL+L
Sbjct 125 LSDTFTFADWVTQEQLPVILVVGVKLGCINHAMLTAQVIQHAGLTL 170
>P46397 ATP-dependent dethiobiotin synthetase BioD [Corynebacterium
glutamicum (strain ATCC 13032 / DSM 20300 / BCRC 11384
/ JCM 1318 / LMG 3730 / NCIMB 10025)]
Length=224
Score = 86.3 bits (212), Expect = 4e-24
Identities = 55/165 (33%), Positives = 88/165 (53%), Gaps = 9/165 (5%)
Query 7 FISGIDTGIGKTYATGYLAKQWIDQGIKTITQKLIQTGNIEISEDIEKHRDIMQTGFLPE 66
F+SG TG+GKT++T L + DQG + KL+QTG + DI + TG E
Sbjct 5 FVSGTGTGVGKTFSTAVLVRYLADQGHDVLPVKLVQTGELPGEGDIFNIERL--TGIAGE 62
Query 67 DDEKLTMPEIFTYPASPHLATKMDG-RALDFNKIEQATHILKQRFDVVLLEGAGGLMVPL 125
+ + F P +P+LA + +G + F++I ++++EGAGGL+V L
Sbjct 63 EFAR------FKDPLAPNLAARREGVEPIQFDQIISWLRGFDDPDRIIVVEGAGGLLVRL 116
Query 126 TTDMLTIDYIAEHQFPIILVSSGRLGSINHTLLSLEAIKQRGLSL 170
D D + P+++V+S LGS+N LS+EA +RGL++
Sbjct 117 GEDFTLADVASALNAPLVIVTSTGLGSLNAAELSVEAANRRGLTV 161
>O06899 ATP-dependent dethiobiotin synthetase BioD [Pseudescherichia
vulneris]
Length=240
Score = 85.9 bits (211), Expect = 7e-24
Identities = 50/166 (30%), Positives = 85/166 (51%), Gaps = 1/166 (1%)
Query 6 YFISGIDTGIGKTYATGYLAKQWIDQGIKTITQKLIQTGNIEISEDIEKHRDI-MQTGFL 64
YF++G DT +GKT A+ L + G +T K + +G+ E + + +Q
Sbjct 5 YFVTGTDTEVGKTVASCALLQAAAQAGWQTAGYKPVASGSEMTPEGLRNSDALALQHNST 64
Query 65 PEDDEKLTMPEIFTYPASPHLATKMDGRALDFNKIEQATHILKQRFDVVLLEGAGGLMVP 124
+ P F P SPH+ + G+ ++ + +L+ + + VL+EGAGG P
Sbjct 65 LALRYEAVNPYTFAEPTSPHIVSAALGQPIEAETLSAGLRMLEAQAEWVLVEGAGGWFTP 124
Query 125 LTTDMLTIDYIAEHQFPIILVSSGRLGSINHTLLSLEAIKQRGLSL 170
L+ + D+ + Q P+ILV +LG INH +L+ +A++Q GL L
Sbjct 125 LSETLTFADWATQEQLPVILVVGVKLGCINHAVLTAQAVQQAGLRL 170
>P53558 ATP-dependent dethiobiotin synthetase BioD [Bacillus subtilis
(strain 168)]
Length=231
Score = 84.0 bits (206), Expect = 3e-23
Identities = 53/180 (29%), Positives = 90/180 (50%), Gaps = 6/180 (3%)
Query 6 YFISGIDTGIGKTYATGYLAKQWIDQGIKTITQKLIQTGNIEISEDIEKH--RDIMQTGF 63
+F++G DT +GKT + LA D K +G D + +D+ QT
Sbjct 4 FFVTGTDTEVGKTVISSGLAALLKDNNRHVGVYKPFLSGISRHHPDSDTSLLKDMSQTSL 63
Query 64 LPEDDEKLTMPEIFTYPASPHLATKMDGRALDFNKIEQATHILKQRFDVVLLEGAGGLMV 123
ED P F P +P++A K++G+ + ++ ++++ + ++EGAGG+ V
Sbjct 64 SHED----ITPFAFKAPLAPYVAGKLEGKTVTMEEVLSHWGRIREKHECFIVEGAGGISV 119
Query 124 PLTTDMLTIDYIAEHQFPIILVSSGRLGSINHTLLSLEAIKQRGLSLYALAYNLNDESQD 183
PL D L I Q P+I+V+ RLG+INHT L+++ + GL + + N +S D
Sbjct 120 PLGEDYLVSHVIKALQLPMIIVARPRLGTINHTFLTVKYAESMGLPIAGIIINGISDSPD 179
Score = 16.5 bits (31), Expect = 7.9
Identities = 7/12 (58%), Positives = 10/12 (83%), Gaps = 1/12 (8%)
Query 65 PEDDEKLTMPEI 76
P++DEK T PE+
Sbjct 178 PDEDEK-TNPEM 188
>O24872 ATP-dependent dethiobiotin synthetase BioD [Helicobacter
pylori (strain ATCC 700392 / 26695)]
Length=218
Score = 75.9 bits (185), Expect = 3e-20
Identities = 57/178 (32%), Positives = 91/178 (51%), Gaps = 11/178 (6%)
Query 7 FISGIDTGIGKTYATGYLAKQWIDQGIKTITQKLIQTG-NIEISEDIEKHRDIMQTGFLP 65
FIS +T GKT LA+ G+KTI K I+TG N I+ + H + L
Sbjct 3 FISATNTNAGKTTCARLLAQYCNACGVKTILLKPIETGVNDAINHSSDAHLFLQDNRLL- 61
Query 66 EDDEKLTMPEIFTYP----ASPHLATKMD--GRALDFNKIEQATHILKQRFDVVLLEGAG 119
D LT+ +I Y ++P +A + + +D + + Q H + +D+V++EGAG
Sbjct 62 --DRSLTLKDISFYRYHKVSAPLIAQQEEDPNAPIDTDNLTQRLHNFTKTYDLVIVEGAG 119
Query 120 GLMVPLTTDMLTIDYIAEHQFPIILVSSGRLGSINHTLLSLEAIKQRGLSLYALAYNL 177
GL VP+T + +D+ + + ++L+S LG IN LL+ +K L Y +A NL
Sbjct 120 GLCVPITLEENMLDFALKLKAKMLLISHDNLGLINDCLLNDFLLKSHQLD-YKIAINL 176
>P53630 Dethiobiotin synthetase [Saccharomyces cerevisiae (strain
ATCC 204508 / S288c)]
Length=237
Score = 58.9 bits (141), Expect = 5e-14
Identities = 55/196 (28%), Positives = 87/196 (44%), Gaps = 34/196 (17%)
Query 5 VYFISGIDTGIGKTYATGYLAKQWIDQGIKTITQKLIQTGNIEISEDIEKHRDIMQTGFL 64
+ F++G DT +GKT+ + L +W K K +QTG D E ++
Sbjct 13 IVFVTGTDTDVGKTFVSTLLVHKW-----KAAYWKPVQTGIESDQGDSETLKNFKIAA-- 65
Query 65 PEDDEKLTMPEIFT------YPASPHLATK----MDGRALDFNKIEQATHILKQRFDVVL 114
P IFT P SP A + +D R LDF E+ + + ++
Sbjct 66 -----STWQPPIFTPTYALQKPLSPLQAMEYEPNVDIRLLDFVVPEEWS-----AENPLV 115
Query 115 LEGAGGLMVPLTTDM-LTIDYIAE------HQFPIILVSSGRLGSINHTLLSLEAIKQRG 167
+EGAGG+ VP+T + +T D I H +++V+ LG++NHTLL+ + G
Sbjct 116 VEGAGGVCVPITRKLEITTDLIKHLIETSGHPVYVVVVARSGLGTLNHTLLTWNHLCDNG 175
Query 168 LSLYALAYNLNDESQD 183
L + LN E +
Sbjct 176 LRSHLFGVILNGEPNE 191
>P9WPQ5 Dethiobiotin synthetase BioD [Mycobacterium tuberculosis
(strain ATCC 25618 / H37Rv)]
Length=226
Score = 56.6 bits (135), Expect = 3e-13
Identities = 48/172 (28%), Positives = 81/172 (47%), Gaps = 9/172 (5%)
Query 4 SVYFISGIDTGIGKTYATGYLAKQWIDQGIKTITQKLIQTGNIEISEDIEKHRDIMQTGF 63
++ ++G TG+GKT LA GI K +QTG + D+ + G
Sbjct 2 TILVVTGTGTGVGKTVVCAALASAARQAGIDVAVCKPVQTGTARGDD------DLAEVGR 55
Query 64 LPEDDEKLTMPEIFTYPASPHLATKMDGRALDF-NKIEQATHILKQRFDVVLLEGAGGLM 122
L + + + P +P A + G AL ++I + L + + L+EGAGGL+
Sbjct 56 LAGVTQLAGLAR-YPQPMAPAAAAEHAGMALPARDQIVRLIADLDRPGRLTLVEGAGGLL 114
Query 123 VPLTTDMLTI-DYIAEHQFPIILVSSGRLGSINHTLLSLEAIKQRGLSLYAL 173
V L +T+ D + ++V + LG++NHT L+LEA+ + +S L
Sbjct 115 VELAEPGVTLRDVAVDVAAAALVVVTADLGTLNHTKLTLEALAAQQVSCAGL 166
>Q52312 Protein IncC [Escherichia coli]
Length=358
Score = 36.6 bits (83), Expect = 3e-06
Identities = 35/135 (26%), Positives = 59/135 (44%), Gaps = 19/135 (14%)
Query 14 GIGKTYATGYLAKQWIDQGIKTITQKLIQTGNIEISEDIEKHRDIMQTGFLPEDDE---- 69
G GKT+AT +LA ++++G++ L GN + + + F + D+
Sbjct 116 GQGKTFATCHLAFDFLERGLRVAVIDLDTQGNASFTLSAYQSGYLASQLFTGDTDDLRYW 175
Query 70 --KLTMPEIFTYPASPHLATKMDGRALDFNKIEQATHILK-------QRFDVVLLEGAGG 120
K + A +LA LD ++ QA L+ + FDV L++ A
Sbjct 176 FGKREGESLALIAADANLAN------LDKMELSQAAAALRASVAALGEFFDVCLIDTAPS 229
Query 121 LMVPLTTDMLTIDYI 135
L V +T +LT DY+
Sbjct 230 LGVAMTAAVLTADYM 244
Lambda K H a alpha
0.321 0.138 0.399 0.792 4.96
Gapped
Lambda K H a alpha sigma
0.267 0.0410 0.140 1.90 42.6 43.6
Effective search space used: 674584
Database: 17d580adec08f25d1c897b04bda9368f.SwissProt.fasta
Posted date: May 9, 2024 3:18 PM
Number of letters in database: 4,804
Number of sequences in database: 21
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Neighboring words threshold: 11
Window for multiple hits: 40
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Data ...
