BLASTP 2.12.0+
Reference: Stephen F. Altschul, Thomas L. Madden, Alejandro A.
Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J.
Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of
protein database search programs", Nucleic Acids Res. 25:3389-3402.
Reference for composition-based statistics: Alejandro A. Schaffer,
L. Aravind, Thomas L. Madden, Sergei Shavirin, John L. Spouge, Yuri
I. Wolf, Eugene V. Koonin, and Stephen F. Altschul (2001),
"Improving the accuracy of PSI-BLAST protein database searches with
composition-based statistics and other refinements", Nucleic Acids
Res. 29:2994-3005.
Database: 82f2c4205203f9b6fe090619b6431083.SwissProt.fasta
10 sequences; 32,152 total letters
Query= ACIAD0940
Length=3712
Score E
Sequences producing significant alignments: (Bits) Value
Q7CGD9 Toxin CdiA [Yersinia pestis] 511 1e-147
I1WVY3 tRNA nuclease CdiA-2 [Burkholderia pseudomallei (strain 10... 434 3e-124
D5CBA0 16S rRNA endonuclease CdiA [Enterobacter cloacae subsp. cl... 387 5e-110
A0A1S4NYE3 tRNA nuclease CdiA [Escherichia coli (strain STEC_O31)] 379 1e-107
P0DSI1 tRNA nuclease CdiA [Escherichia coli (strain NC101)] 368 4e-104
Q0T963 tRNA nuclease CdiA [Escherichia coli O6:K15:H31 (strain 53... 367 9e-104
C4SGN7 tRNA nuclease CdiA [Yersinia mollaretii (strain ATCC 43969... 362 2e-102
Q3YL96 Toxin CdiA [Escherichia coli] 362 2e-102
B3BM48 tRNA nuclease CdiA [Escherichia coli O157:H7 (strain EC869)] 361 5e-102
E0SDG8 Deoxyribonuclease CdiA [Dickeya dadantii (strain 3937)] 268 7e-74
>Q7CGD9 Toxin CdiA [Yersinia pestis]
Length=3295
Score = 511 bits (1315), Expect = 1e-147
Identities = 536/1952 (27%), Positives = 842/1952 (43%), Gaps = 317/1952 (16%)
Query 1 MNKNRYRIIFSQARGMFIAVAEIVKSKTKQAGQSQADGHDNKACSASDSDSMGFDSSHLK 60
MNKN YRI+F+QARGM + VA+I S + S GH + +
Sbjct 1 MNKNLYRIVFNQARGMLMVVADIAASGRAASSPSSGVGHTQRR--------------RVS 46
Query 61 KLKQLNFAVISVLGASIFTLPLNTIADSQIIADKGAPTSQQPTILNSSNGVTQVNIQTPS 120
L L+F ++ LG ++ A + I+AD AP +QQPTI++S+NG QVNIQTPS
Sbjct 47 ALSPLSFRLLIALGC------ISLSAQAAIVADGSAPGNQQPTIISSANGTPQVNIQTPS 100
Query 121 AGGVSRNTYSQFDVGQEGAILNNARNNTQTQLGGWIQGNPWLAKGEAKVILNEVNSSNPS 180
+GGVSRN Y QFDV G ILNN R QTQ+ G + GNPWLA+GEA VILNEVNS +PS
Sbjct 101 SGGVSRNAYRQFDVDNRGVILNNGRGVNQTQIAGLVDGNPWLARGEASVILNEVNSRDPS 160
Query 181 QLKGYIEVAGKQAQVVIANPSGLVCDGCGVINADRFTLTTGQAVMNQGYLESFRVREGQI 240
QL GYIEVAG++AQVVIANP+G+ C+GCG INA+R TLTTGQA +N G L + V G+I
Sbjct 161 QLNGYIEVAGRKAQVVIANPAGITCEGCGFINANRATLTTGQAQLNNGQLTGYDVERGEI 220
Query 241 TIQGKGLNGSLTPFTDVYARALQVNAGLYAKELNVVLGQNDINVNDPTTSNVSPIQSNTS 300
IQGKGL+ TD+ AR+++VNAG++A ELN+ G+N + D N++ +
Sbjct 221 VIQGKGLDSRGQDHTDLIARSVKVNAGIWANELNITTGRNQV---DAAHQNIN--TNAAD 275
Query 301 ANNKPQFALDVGQLGGMYAGKIFLVGTEQGVGVRNAGSMNSTQSTLTLNANGDLTNTGNL 360
++P A+DV LGGMYAGKI L+GTE GVGV NAG + ++ + + A+G L N G +
Sbjct 276 GRHRPAVAVDVANLGGMYAGKIRLIGTETGVGVHNAGEIGASAGDIVITADGMLVNRGQI 335
Query 361 IANQGQLQLNAENIKNTGNISSATSQVSLHSQNLDNSGLISSADELNIQQQGHVGNRGTL 420
+ Q QL +N + ++NSG++ + G + N GT+
Sbjct 336 SSAQ-QLAVNTPS-------------------GIENSGVLYGKGNTQLTTAGKLSNSGTV 375
Query 421 NAARIVVDAGSLANSGSIEQTGAQALDLKAGSMSNIGGKIGIAKTSSTGGNGSESGGGSQ 480
AA + + NS GA +K+ + + G + I G G +Q
Sbjct 376 AAAGDTLIRAAEVNSSRNSVLGA---GIKSDNSAITRGTLDIKARGQLTAQGKNISGTAQ 432
Query 481 PVEPNNAAQDGGSLEVVNTDSTPTTPKTYETGYIHVRDQLNNDQGAIVAQGGIDLESNNG 540
N G + + D T TT +G + G +L +N
Sbjct 433 TFNANRIDLSGSQTQ--SGDLTFTT------------------EGGDIDLTGANLFANRR 472
Query 541 LDNQGGQLNLGRVKIQGERFNNDQGQLTVKQAEIQTNSLSNQSGQLISNQKLNIQTQTAN 600
L L D+ L +Q + +L+N G + TQT
Sbjct 473 LSVSTPSL-----------LRTDKANLFAEQIALDAQALANVGG---------VITQT-- 510
Query 601 NQKGKIQSVDQLDLNVANGLNNIEGQIASGQQLNIQADQV--NNQSGLIYSEQQGIELKA 658
+ +LN+ ++N +G + + +QA+ + N+QS L Q +L
Sbjct 511 -------GLTDFNLNLPGDIDNRDGTLLTRGNFLLQAEHLTSNSQSLLGAGIQSDGKLAP 563
Query 659 NHAINNTSG---IIQAKT----QLNLASTQLDNTSGHIQAENIQQQHT--TVNNTQGSIV 709
+N T+ I Q KT L L+ ++LD T QA+ ++ T + T +++
Sbjct 564 RGDLNVTTRHALIAQGKTLTAGTLALSGSRLDLTDSLTQAKYMRLTATEGDIALTGATVM 623
Query 710 AGQSLISTVDQ-FDNHQGLIDAKNIQLTHQVLNN-SGSIY----ADQNIKITGQHILNTG 763
A +L + Q + + + A I LT L+N G + D + + G G
Sbjct 624 AANTLFADTRQILRSDKAYLTADQINLTAYSLSNVEGRVVQKGSGDFRLDLPGYLDNRGG 683
Query 764 SIAAGQNIQLNTAKLQHEQAALIAAGLDRQGKLTSTGDLDITAEQTTL-HGQSFAGQQLK 822
+ N+ L +L +L+ AG+ G S GDL Q + GQ+ A +
Sbjct 684 VLLTKGNLALQAERLTSNSQSLLGAGIQADGSKASKGDLQANTTQALIAQGQNVAAGTMT 743
Query 823 VASKQQIDATNGQLQAKNIDLASDAGDISTRAATVIAE-QLSLKS----HDLIDNQQGTL 877
+ S ++D T Q A NI + + GD++TR AT+I LS+ + ++N+ G L
Sbjct 744 L-SGSRVDLTGSQTHASNITITARDGDVTTREATLITPGTLSMTAVANPEQTLNNRGGKL 802
Query 878 SAQQLNLTANRLDNTQGHILHTGQDQLDLNFSQSLNNQLGEIRSNAAEL--NIKTALLNN 935
A + L +L+N+ G I L L +Q G + +L N + AL+N
Sbjct 803 HADNIQLNLAKLENSNGEI--AAATDLWLRLQSDFIHQAGARLTAGRDLLFNSRGALINQ 860
Query 936 TE---GQVVHAGTQQLNIQTAQLNGHLGH--ILSNGTLQLKAGTLDVSGGV--TSADQIT 988
+ G+ + + +A N + + +L+ L L +L G + T Q T
Sbjct 861 YKLEAGRDMQLTALSIRNTSADRNTNADNSSLLAGRGLSLSTDSLFNRGAIYTTGVGQFT 920
Query 989 IQANVLN------------NAQGQLIQRG---TSNPLNLTIQQQLNNQAGLIQSATATDI 1033
+ N N A G L RG T + L+ Q +NN L + +
Sbjct 921 VNGNTENIGEIYTEQQLTFTATGNLANRGVMQTRGEMQLSAQGDVNNSGMLYSAGDQMRL 980
Query 1034 K-AGSLNNQRGTLSSAQGQNLDVDVAGKLDNSQSGQIY-AGNQAHLQVGSIDNSHQGQIN 1091
AG+L N+ G L A G+ + + G LDN G +Y AGN G+ N+ G +
Sbjct 981 SIAGNLTNE-GKLHVANGE-MRLLTEGNLDN--RGSLYGAGNSDITTQGNAVNT--GSVY 1034
Query 1092 AQQNLQLTSQQQINNQSGQIVANGDVQIQSQGL---NNSHGQMGSLQGGLSLNTGSDTLI 1148
Q LQ ++ + N S I A GD+Q+++ L N S G G ++G+ +
Sbjct 1035 TQGALQWLTKGSVRN-SASIAALGDLQLRANDLLSDNQSLMAAGLKADGSRSDSGNLAVS 1093
Query 1149 NQSGLIQAKKDIGIQAQRIDNQQGQIT-TQGQAELIS---------------QAEIDNLE 1192
+ LI ++I + + Q +T +Q QA IS +A L
Sbjct 1094 TEQALIAQGQNIAAGSLALAGSQIDLTGSQTQANAISLTAKSGDITLTSAVIKAATQLLV 1153
Query 1193 GAIAADLDVNIRSQGLNNNKGQISSAQGNLTLNAGNGTLTNQAATIVSGKTLTLSANQLD 1252
+AA I + + Q SS Q + + +A T++A+ I T + A
Sbjct 1154 TQLAATRSSFIPPSSIPPSSTQSSSTQASASPSA--WLRTDKASLIADQLTFDVQA---- 1207
Query 1253 NSNHGQINSQNNA---DISIVKDINNTSGVIAAKQQLILSSQGLNNTTGQI---GTVQGN 1306
SN G + +Q A ++++ ++N G I +K + + +QGL++ +G + G
Sbjct 1208 LSNLGGVIAQTGATDFNLNLPGYLDNRGGTILSKGNVAIQAQGLDSDSGSLLGAGVQSDG 1267
Query 1307 LHIDAGSQLLNNQQGRIQSGQDL-----NLNATGIDNTQGQISSK--------------- 1346
+AG + +Q I GQ L L +G+D T Q ++
Sbjct 1268 KLTNAGDLAVTVRQDLIAHGQSLAAGAMTLTGSGVDLTGSQTQARGITITANKGDVSTQR 1327
Query 1347 -NQLQLDS--------REQLLNNRQGTLSAENLTIDSGELNNDQGLIQAQQSIQIDTHQH 1397
N L L S Q LNN+ G+L A N+ ++ G+L+N G I A Q + +
Sbjct 1328 ANILSLGSLAINAGANAGQTLNNQGGSLQANNIALNLGQLDNRTGKIAASQDLVLGLQ-- 1385
Query 1398 NLSNTNSGAQGGILSQGNIQLNNIQTLDNQQGYLASAQQLDLQANQVFNQNGTLLAAKQL 1457
S+ N A + + + L N G L + ++L ++N + N NG + A Q
Sbjct 1386 --SDFNILADSTLQAGRDFSFTTHGALTN-DGQLLAGRKLSTRSNSLLN-NGNIRAV-QA 1440
Query 1458 NLQGTGQNQLLNNQSGQMLSMGGMNLNIDQINNKGKANTADADSHIMAAGELNITTQQLD 1517
+L+ +G L N+ G++L+ GG++ + ANT + +G L T L+
Sbjct 1441 DLRASG---ALTNR-GEILTRGGLSTD---------ANT------LFNSGTLIGATATLN 1481
Query 1518 NQNTLNTDPANTSIQGIDAN-TLNVTSKVLNNQSGVIRSSADQNLN-------VQQALNN 1569
+ + N I D N TL + + V+ N V R+ + +
Sbjct 1482 ARERITNSGPNALIGATDKNGTLALLAPVIENSDTVTRTDTAPTTTLLGMGKVILAGGQD 1541
Query 1570 QSGQISSEKQLTLVGDQLEINNLNGQILAGTALDLIAQSLSGDGKLLS-----------L 1618
SG SS Q + NL+G I +G L + A++L+ ++L+
Sbjct 1542 NSGNYSSAAQ---------VLNLSGLIESGNDLLVYAKTLTNRRQILTATTDFIVGDTET 1592
Query 1619 GNAKLSLQND------YIHSSGAQLQANQDLSLSTKGNIINNGTINAGNQLALNAANITN 1672
G A + +N Y + + + + N + L A
Sbjct 1593 GAAYWTAENPDIPGGRYTQPPAGGPMNSDYIGTNYTSTVAYNRIDQISPEAQLLAGGNLT 1652
Query 1673 QQAGKIESHDTRLTAQNTLNNTGLIN-----GDFTRLQAET------------------- 1708
Q G +E++ ++++AQ ++ TG+ G RL +T
Sbjct 1653 LQVGTLENNWSKVSAQGVIDLTGVTLQQDDWGSQQRLVEQTTSSGEYRYRTYKGKLWGIA 1712
Query 1709 --------LNNQGTGRIYGTTLAIQANTLNNQPDSTGTAP--VIASRGDLHLGVQTLNNL 1758
LNNQ I TL +NN + G AP ++A R G N+
Sbjct 1713 WGPEMKLRLNNQYASSITAKTLTGSGTVINNTVINNGAAPGAIVAPRDRDSTG----KNI 1768
Query 1759 SNPTDYTSQALIFSAGNLYLGAALDANDYATG 1790
+ ++ AL LY D DYA G
Sbjct 1769 A--VEFNGIALTLPRSGLY-QLKTDKGDYAPG 1797
Score = 426 bits (1095), Expect = 9e-122
Identities = 623/2710 (23%), Positives = 1093/2710 (40%), Gaps = 383/2710 (14%)
Query 546 GQLNLGRVKIQGERFN---NDQGQLTVKQAEI--QTNSLSNQSGQLISNQKLNIQTQTAN 600
G + G++++ G ++ G++ +I + + GQ+ S Q+L + T +
Sbjct 290 GGMYAGKIRLIGTETGVGVHNAGEIGASAGDIVITADGMLVNRGQISSAQQLAVNTPSGI 349
Query 601 NQKGKIQSVDQLDLNVANGLNNIEGQIASGQQLNIQADQVNNQSGLIYSEQQGIELKA-N 659
G + L A L+N G +A+ I+A +VN+ + G +K+ N
Sbjct 350 ENSGVLYGKGNTQLTTAGKLSN-SGTVAAAGDTLIRAAEVNSSRNSVL----GAGIKSDN 404
Query 660 HAINNTSGIIQAKTQLNLASTQLDNTSGHIQAENI-------QQQHTTVNNTQGSI-VAG 711
AI + I+A+ QL + T+ A I Q T G I + G
Sbjct 405 SAITRGTLDIKARGQLTAQGKNISGTAQTFNANRIDLSGSQTQSGDLTFTTEGGDIDLTG 464
Query 712 QSL-------ISTVDQFDNHQGLIDAKNIQLTHQVLNNSGSIYA-----DQNIKITGQHI 759
+L +ST + + A+ I L Q L N G + D N+ + G
Sbjct 465 ANLFANRRLSVSTPSLLRTDKANLFAEQIALDAQALANVGGVITQTGLTDFNLNLPGDID 524
Query 760 LNTGSIAAGQNIQLNTAKLQHEQAALIAAGLDRQGKLTSTGDLDITAEQTTL-HGQSFAG 818
G++ N L L +L+ AG+ GKL GDL++T + G++
Sbjct 525 NRDGTLLTRGNFLLQAEHLTSNSQSLLGAGIQSDGKLAPRGDLNVTTRHALIAQGKTLTA 584
Query 819 QQLKVASKQQIDATNGQLQAKNIDLASDAGDISTRAATVIAEQ-LSLKSHDLIDNQQGTL 877
L + S ++D T+ QAK + L + GDI+ ATV+A L + ++ + + L
Sbjct 585 GTLAL-SGSRLDLTDSLTQAKYMRLTATEGDIALTGATVMAANTLFADTRQILRSDKAYL 643
Query 878 SAQQLNLTANRLDNTQGHILHTGQDQLDLNFSQSLNNQLGEIRSNAAELNIKTALLNNTE 937
+A Q+NLTA L N +G ++ G L+ L+N+ G + L ++ L +
Sbjct 644 TADQINLTAYSLSNVEGRVVQKGSGDFRLDLPGYLDNR-GGVLLTKGNLALQAERLTSNS 702
Query 938 GQVVHAGTQ---------QLNIQTAQLNGHLGHILSNGTLQLKAGTLDVSGGVTSADQIT 988
++ AG Q L T Q G ++ GT+ L +D++G T A IT
Sbjct 703 QSLLGAGIQADGSKASKGDLQANTTQALIAQGQNVAAGTMTLSGSRVDLTGSQTHASNIT 762
Query 989 IQANV--LNNAQGQLIQRGTSNPLNLTIQQQLNNQAGLIQSATATDIKAGSLNNQRGTLS 1046
I A + + LI GT S TA +LNN+ G L
Sbjct 763 ITARDGDVTTREATLITPGTL-------------------SMTAVANPEQTLNNRGGKLH 803
Query 1047 SAQGQNLDVDVAGKLDNSQSGQIYAGNQAHLQVGSIDNSHQG--QINAQQNLQLTSQQQI 1104
+ N+ +++A KL+NS +G+I A L++ S D HQ ++ A ++L S+ +
Sbjct 804 A---DNIQLNLA-KLENS-NGEIAAATDLWLRLQS-DFIHQAGARLTAGRDLLFNSRGAL 857
Query 1105 NNQSGQIVANGDVQIQSQGLNNS------HGQMGSLQGGLSLNTGSDTLINQSGLIQAKK 1158
NQ ++ A D+Q+ + + N+ + SL G L+ +D+L N+ +
Sbjct 858 INQY-KLEAGRDMQLTALSIRNTSADRNTNADNSSLLAGRGLSLSTDSLFNRGAIYTT-- 914
Query 1159 DIGIQAQRIDNQQ---GQITTQGQAELISQAEIDNLEGAIAADLDVNIRSQGLNNNKGQI 1215
G+ ++ G+I T+ Q + + N G + ++ + +QG NN G +
Sbjct 915 --GVGQFTVNGNTENIGEIYTEQQLTFTATGNLAN-RGVMQTRGEMQLSAQGDVNNSGML 971
Query 1216 SSAQGNLTLNAGNGTLTNQAAT-IVSGKTLTLSANQLDNSNHGQINSQNNADISIVKDIN 1274
SA + L+ G LTN+ + +G+ L+ LDN G + N+DI+ +
Sbjct 972 YSAGDQMRLSIA-GNLTNEGKLHVANGEMRLLTEGNLDN--RGSLYGAGNSDITTQGNAV 1028
Query 1275 NTSGVIAAKQQLILSSQGLNNTTGQIGTVQGNLHIDAGSQLLNNQQ----------GRIQ 1324
NT V L+ + N+ G+L + A L +NQ R
Sbjct 1029 NTGSVYTQGALQWLTKGSVRNSASIAAL--GDLQLRANDLLSDNQSLMAAGLKADGSRSD 1086
Query 1325 SGQDLNLNATGIDNTQGQISSKNQLQLDSREQLLNNRQGTLSAENLTIDSGELNNDQGLI 1384
SG +L ++ QGQ + L L + L Q +A +LT SG++ +I
Sbjct 1087 SG-NLAVSTEQALIAQGQNIAAGSLALAGSQIDLTGSQTQANAISLTAKSGDITLTSAVI 1145
Query 1385 QAQQSIQID-----------------THQHNLSNTNSGAQGGILSQGNIQLN------NI 1421
+A + + + + S S + L L ++
Sbjct 1146 KAATQLLVTQLAATRSSFIPPSSIPPSSTQSSSTQASASPSAWLRTDKASLIADQLTFDV 1205
Query 1422 QTLDNQQGYLASAQQLDLQAN---QVFNQNGTLLAAKQLNLQGTGQNQLLNNQSGQMLSM 1478
Q L N G +A D N + N+ GT+L+ + +Q G L++ SG +L
Sbjct 1206 QALSNLGGVIAQTGATDFNLNLPGYLDNRGGTILSKGNVAIQAQG----LDSDSGSLLGA 1261
Query 1479 GGMNLNIDQINNKGKANTAD-----------ADSHIMAAGELNITTQQLDNQNTLNTDPA 1527
G + + GK A A +AAG + +T +D + T
Sbjct 1262 G--------VQSDGKLTNAGDLAVTVRQDLIAHGQSLAAGAMTLTGSGVDLTGS-QTQAR 1312
Query 1528 NTSIQGIDANTLNVTSKVLNNQSGVIRSSADQNLNVQQALNNQSGQISSEKQLTLVGDQL 1587
+I + + +L+ S I + A N Q LNNQ G + + +G
Sbjct 1313 GITITANKGDVSTQRANILSLGSLAINAGA----NAGQTLNNQGGSLQANNIALNLG--- 1365
Query 1588 EINNLNGQILAGTALDLIAQSLSGDGKLLSLGNAKLSLQNDYIHSSGAQLQANQDLSLST 1647
+++N G+I A DL+ L LQ+D+ + + LQA +D S +T
Sbjct 1366 QLDNRTGKIAASQ--DLV-----------------LGLQSDFNILADSTLQAGRDFSFTT 1406
Query 1648 KGNIINNGTINAGNQLALNAANITNQQAGKIESHDTRLTAQNTLNNTG--LINGDFTRLQ 1705
G + N+G + AG +L+ + ++ N G I + L A L N G L G +
Sbjct 1407 HGALTNDGQLLAGRKLSTRSNSLLNN--GNIRAVQADLRASGALTNRGEILTRGGLST-D 1463
Query 1706 AETLNNQGTGRIYGTTLAIQA---------NTLNNQPDSTGTAPVIASRGDLHLGVQTLN 1756
A TL N GT + G T + A N L D GT ++A V +
Sbjct 1464 ANTLFNSGT--LIGATATLNARERITNSGPNALIGATDKNGTLALLAP-------VIENS 1514
Query 1757 NLSNPTDYTSQALIFSAGNLYLGAALDANDYATGQADVIHNESATIESLGDMNLSAKQIN 1816
+ TD + G + L D + + A V+ N S IES D+ + AK +
Sbjct 1515 DTVTRTDTAPTTTLLGMGKVILAGGQDNSGNYSSAAQVL-NLSGLIESGNDLLVYAKTLT 1573
Query 1817 NINKYFK--TEQVEVSRKDGLEKYCDAWCTFDGNYYDGNPYEDWMRY------YYSEITY 1868
N + T+ + + G + G Y P M Y S + Y
Sbjct 1574 NRRQILTATTDFIVGDTETGAAYWTAENPDIPGGRYTQPPAGGPMNSDYIGTNYTSTVAY 1633
Query 1869 ETRTTESAPGQIKAGGHLDLNGAQVVNDKSQILAGGELKNEGGTI---DSGTQIAGIRKI 1925
S Q+ AGG+L L + N+ S++ A G + G T+ D G+Q + +
Sbjct 1634 NRIDQISPEAQLLAGGNLTLQVGTLENNWSKVSAQGVIDLTGVTLQQDDWGSQQRLVEQT 1693
Query 1926 VNTGTQVKYWKYEGQ-----WD-------NPFENSSETTFDLSISQALGNQNLNQNQLST 1973
++G + +Y Y+G+ W N SS T L+ S + N + N +
Sbjct 1694 TSSG-EYRYRTYKGKLWGIAWGPEMKLRLNNQYASSITAKTLTGSGTVINNTVINNGAAP 1752
Query 1974 VAVSNNQSAEHIQNSQTTQQEINGLQTSNNNTQLNQTKDVDLDQLNLKDSQSQNAPQASA 2033
A+ + + + E NG+ + + L Q LK + AP A
Sbjct 1753 GAIVAPRDRD--STGKNIAVEFNGIALTLPRSGLYQ----------LKTDKGDYAPGPEA 1800
Query 2034 VETVQQQSATSAPSST-PQGTSEEIRSIDFSNIKVPNSALYKVNADSKAGYLIETDPAFA 2092
++ S S+ +T P+G ++ + + P+ A+ GYL+ET PAFA
Sbjct 1801 ALSLANISPPSSLDATGPRGVPPPSDDLNRTGLVTPDRAV-------SGGYLVETHPAFA 1853
Query 2093 DYKKWLSSDYMLDALGLDPALQQKRLGDGFYEQRLVQDQIANLTGYRFLEGFANDDEQYK 2152
W SD L L DP++ KRLGD YEQRL++DQ+ LTG + ++ Q++
Sbjct 1854 SLNNWKGSDLYLQQLSSDPSVIHKRLGDNAYEQRLLRDQVLALTGRTVASDYRSEQAQFE 1913
Query 2153 ALMNNGITFAKLYGLRPGIALTAAQTAQLTSDIVWLVEQSVTLPDGTITKALVPQVYVK- 2211
L G+ ++K + L PG L+A Q A LT +IV + + V LVP VY+
Sbjct 1914 QLFAAGVQYSKAFNLAPGTRLSAEQMATLTGNIVLMENRDV-----AGQTVLVPVVYLAG 1968
Query 2212 VRVGDLKGDGTLLSGNSVNLKLDGDLINGATIAGREALQITADNVQNLNGRI----QGNQ 2267
V+ GDL+ +G L++ +++L N I+ LQI+ LN R GN
Sbjct 1969 VKPGDLRANGALIAAENISLTEVQGFANAGAISASNNLQISMAKDITLNNRCGLLQAGNH 2028
Query 2268 VAIET-QKDLNNIGGQIIAKDAMALKVGGNLNIESTTRTSESKVGNFSSSITNVDRVAGL 2326
+ + T D++ ++ A + + L G ++ + + + S G + T + +A L
Sbjct 2029 LQLSTLNSDIDLTSARLNATN-LQLDSGRDVILRTASDQYSSGNGAVQRTQTILGPLASL 2087
Query 2327 YVGNGS--TKQLDPNQATLMLNVAGNSSLKGVQINNSNSATVLNTTGNVDLGTVSVGKQE 2384
+ N + T Q D Q +N+ K +Q+ NT G+ L TV Q
Sbjct 2088 NISNNAVITAQRDFIQQGAGINIG-----KDLQV---------NTGGDWLLSTVQRSDQI 2133
Query 2385 TLKIDDKNGYQLKQQQDVGSQIKSAGSLLINGQNITSKAVDLNSQQGDIQLSAQKDIVLD 2444
+ + + + +GS++K G+L N N+T+ +N+ G I + AQ +I L
Sbjct 2134 SAQYGGGSATS-GSLRHLGSEVKVGGALSANVDNLTAVGARVNA--GTIDVRAQ-NITLS 2189
Query 2445 NGLNQSTVSSQSQSKGSFGGKKSSTYDASSSTSIANQLNAGQNIIINSAQG-NISATHLQ 2503
+ +V+ S SK + +S+ + T + +QLNA +I + + +SA+ +Q
Sbjct 2190 AATDSLSVTGGSSSK-----RHTSSVNLYDETLLGSQLNATGDINLQTVNDITLSASAVQ 2244
Query 2504 AEAGNNIQIHAQQGNVTLLSAID--DKRESSTSSKKGVATYNNRQSGYIDQEVAQTTLKA 2561
+ + A G+VTL S + D++ + T +KKG+ + +S +E TL
Sbjct 2245 TDGALKL---AAGGDVTLTSQTEQHDEQRNHTGTKKGLLSSTTTRS----EEGRSQTLAV 2297
Query 2562 GDTVDINAAKNIELQANDVQAGNSIYVGNTLMQRQADGSLKAADGSLMPENVTLSTLATK 2621
G + +A +I++ + ++ S V + ++ +A EN+T+ST
Sbjct 2298 GSML---SAGSIDVSSQNIAVAGSSVVADKDIRLRAQ------------ENLTVSTAQQS 2342
Query 2622 D--EQWDEQQKGYRGIVKDIVKATAVGLAGIEALAPGLKAPKITVSESTGKRTEQISQTG 2679
+ Q EQ+K G++ +G T + T +T+ +S G
Sbjct 2343 ESGSQLFEQKKS--GLMSTGGIGVFIG----------------TSRQKTTDQTQTVSHVG 2384
Query 2680 SSLKA--DNVYVGSSGQTTLTSTDITA-KNTILLGQKVTLNAAE---EQKITVESTSKET 2733
S++ + NV + + Q TL +D+ A K+ L G V ++AAE Q+ T ES +
Sbjct 2385 STVGSLTGNVRLEAGNQLTLHGSDVVAGKDLALTGADVAISAAENSRSQQYTAESKQRGL 2444
Query 2734 VQGLGAKLNKDSIRLGGFVLEDASQSSKTT--ETTHKLGSINTENLKIQGVEGVDILGQN 2791
L + G + A ++K E T +L + + GV+ V GQ
Sbjct 2445 TVALSGPV--------GSAVNTAVTTAKAAREENTGRLAGLQGVKAALSGVQAVQ-AGQL 2495
Query 2792 ITATGDTLIDHGRGDLNVGGYENKTTVEDKTHVETISTEVGVRNAYLDAALALGAVKDAA 2851
+ A G + + +++G ++ + + + + V + L A L
Sbjct 2496 VQAQGGGITEMVGVSVSLGSQKSSSQQQQE--------QTQVSGSALTAGNNL------- 2540
Query 2852 EAVKQAKDQYSQAQRDYASGKITKEALDDSKANVAMATANLANAQIAVGSAAATAAASSA 2911
++K + A +G T+ LD ++ + AN + S + S
Sbjct 2541 -SIKASGSDILIAGSQLKAGGDTR--LDAARDVQLLGAANRQKTDGSNSSRGGSVGVSVG 2597
Query 2912 TYGFTIGANGERIETTNTTNTTQGKWQGSTLELNNLTLKSENQDVNVQGSRLTATGTTSF 2971
G ++ AN + + + T W +T++ + +D + G++++A T
Sbjct 2598 GSGLSVFANANKGQGNERGDGT--FWTETTVDSGGMFSLRSGRDTALTGAQVSAE-TVKA 2654
Query 2972 DGTKDLNVTAGTEHSQQETSSKTNSQSVSYTYGGGGSASIGKQTSTSESKSLTYVNSEVT 3031
D ++L + + + + S +S GGG+A + S V ++
Sbjct 2655 DVGRNLTLQSQQDRDNYDAKQSRASGGISVPVAGGGAAVNLSMSRDRLSSQYDSVQAQTG 2714
Query 3032 LNKTEGRLNSLNIKGGE-----------VSIQDRGNLQVNNIHVESLQDTASSSNSSRGG 3080
+ G ++I+ GE + D+ L + +++ A + +GG
Sbjct 2715 IFAGSG---GVDIRVGEHTQLDGAVIASTAAADKNTLDTGTLGFSDIKNKAVFTVEHQGG 2771
Query 3081 SIGGGYGSGS 3090
S+ G GS
Sbjct 2772 SLSTGGPVGS 2781
Score = 62.0 bits (149), Expect = 2e-11
Identities = 232/1167 (20%), Positives = 414/1167 (35%), Gaps = 248/1167 (21%)
Query 2238 INGATIAGREALQITADNVQNLNGRIQGN--QVAIETQKDLNNIGGQIIAKDAMALKVGG 2295
IN GR + D V NL G G + ET ++N G + + + G
Sbjct 269 INTNAADGRHRPAVAVD-VANLGGMYAGKIRLIGTETGVGVHNAGEIGASAGDIVITADG 327
Query 2296 NLNIESTTRTSESKVGNFSSSITNVDRVAGLYVGNGSTKQLDPNQATLMLNVA--GNSSL 2353
L +++ N S I N +G+ G G+T+ + + VA G++ +
Sbjct 328 MLVNRGQISSAQQLAVNTPSGIEN----SGVLYGKGNTQLTTAGKLSNSGTVAAAGDTLI 383
Query 2354 KGVQINNSNS----ATVLNTTGNVDLGTVSVGKQETLKIDDKNGYQLKQQQDVGSQIKSA 2409
+ ++N+S + A + + + GT+ + + L KN +Q +A
Sbjct 384 RAAEVNSSRNSVLGAGIKSDNSAITRGTLDIKARGQLTAQGKN-------ISGTAQTFNA 436
Query 2410 GSLLINGQNITSKAVDLNSQQGDIQLSAQKDIVLDNGLNQST---------------VSS 2454
+ ++G S + ++ GDI L+ ++ + L+ ST ++
Sbjct 437 NRIDLSGSQTQSGDLTFTTEGGDIDLTGA-NLFANRRLSVSTPSLLRTDKANLFAEQIAL 495
Query 2455 QSQSKGSFGGKKSSTYDASSSTSIANQLNAGQNIIINSAQGNISATHL----QAEAGNNI 2510
+Q+ + GG + T + ++ ++ ++ + A HL Q+ G I
Sbjct 496 DAQALANVGGVITQTGLTDFNLNLPGDIDNRDGTLLTRGNFLLQAEHLTSNSQSLLGAGI 555
Query 2511 QIHAQQG-----NVTLLSAIDDKRESSTSSKKGVATYNNRQSGYIDQ-EVAQTTLKAGDT 2564
Q + NVT A+ + ++ T+ ++ + + Q + + T GD
Sbjct 556 QSDGKLAPRGDLNVTTRHALIAQGKTLTAGTLALSGSRLDLTDSLTQAKYMRLTATEGD- 614
Query 2565 VDINAAKNIELQANDVQAGNSIYVGNTLMQRQADGSLKAADGSLMPENVTLSTLATKDEQ 2624
I L V A N+++ + R L A + + L+ + + +
Sbjct 615 --------IALTGATVMAANTLFADTRQILRSDKAYLTA-------DQINLTAYSLSNVE 659
Query 2625 WDEQQKGYRGIVKDI-----------------------VKATAVGLAGIEALAPGLKAPK 2661
QKG D+ + + + L G A G KA K
Sbjct 660 GRVVQKGSGDFRLDLPGYLDNRGGVLLTKGNLALQAERLTSNSQSLLGAGIQADGSKASK 719
Query 2662 ITVSESTGKRTEQISQTGSSLKADNVYVGSS------GQTTLTSTDITAKNTILLGQKVT 2715
+ +T T+ + G ++ A + + S QT ++ ITA++ + ++ T
Sbjct 720 GDLQANT---TQALIAQGQNVAAGTMTLSGSRVDLTGSQTHASNITITARDGDVTTREAT 776
Query 2716 LNAAEEQKITVESTSKETVQGLGAKLNKDSIRLGGFVLEDAS-QSSKTTETTHKLGSINT 2774
L +T + ++T+ G KL+ D+I+L LE+++ + + T+ +L S
Sbjct 777 LITPGTLSMTAVANPEQTLNNRGGKLHADNIQLNLAKLENSNGEIAAATDLWLRLQSDFI 836
Query 2775 ENLKIQGVEGVDILG-------------------------QNITATGDTLIDH-----GR 2804
+ G D+L +N +A +T D+ GR
Sbjct 837 HQAGARLTAGRDLLFNSRGALINQYKLEAGRDMQLTALSIRNTSADRNTNADNSSLLAGR 896
Query 2805 G-DLNVGGYENK----TTVEDKTHVETISTEVGVRNAYLDAALALGAVKDAAE-AVKQAK 2858
G L+ N+ TT + V + +G Y + L A + A V Q +
Sbjct 897 GLSLSTDSLFNRGAIYTTGVGQFTVNGNTENIG--EIYTEQQLTFTATGNLANRGVMQTR 954
Query 2859 DQYS-QAQRDYASGKITKEALDDSKANVAMATANLANAQIAVGSAAATAAASSATYGFTI 2917
+ AQ D + + A D + ++A N +A G + G
Sbjct 955 GEMQLSAQGDVNNSGMLYSAGDQMRLSIAGNLTNEGKLHVANGEMRLLTEGNLDNRGSLY 1014
Query 2918 GANGERIETT-NTTNT----TQGKWQGST---------------LELNNLTLKSENQDVN 2957
GA I T N NT TQG Q T L+L L S+NQ +
Sbjct 1015 GAGNSDITTQGNAVNTGSVYTQGALQWLTKGSVRNSASIAALGDLQLRANDLLSDNQSLM 1074
Query 2958 VQGSRLTATGTTSFDGTKDLNVTAGTEHSQQETSSKTNSQSVSYTYGGGGSASIGKQTST 3017
G L A G+ S G N+ TE + Q+++ G A G Q
Sbjct 1075 AAG--LKADGSRSDSG----NLAVSTEQALI-----AQGQNIA----AGSLALAGSQI-- 1117
Query 3018 SESKSLTYVNSEVTLNKTEGRLNSLNIKGGEVSIQDRGNLQVNNIHVESLQDTASSSNSS 3077
++T ++T+ SL K G++++ + V L T SS
Sbjct 1118 -----------DLTGSQTQANAISLTAKSGDITLTSAVIKAATQLLVTQLAATRSSFIPP 1166
Query 3078 RGGSIGGGYGSGSKNITASYNQSKGSSDSAWVNTTSKLLIGNAQNDANLDAMGVKNITNI 3137
S + T S + +S SAW+ T LI A+ V+ ++N+
Sbjct 1167 ---------SSIPPSSTQSSSTQASASPSAWLRTDKASLI------ADQLTFDVQALSNL 1211
Query 3138 GGVIA-------------------------------------------NANKNADGSLTD 3154
GGVIA A +DG LT+
Sbjct 1212 GGVIAQTGATDFNLNLPGYLDNRGGTILSKGNVAIQAQGLDSDSGSLLGAGVQSDGKLTN 1271
Query 3155 HKNLNYTGNLELKDLQDHNNNNSSGFNVSTNIGIPQGGSKAASTAPKGSTTIGLNSSGQE 3214
+L T +DL H + ++G T G+ GS+ T +G TI N
Sbjct 1272 AGDLAVTVR---QDLIAHGQSLAAGAMTLTGSGVDLTGSQ---TQARG-ITITANKGDVS 1324
Query 3215 TEQLTKATLGQGSVTNATADTNRDINN 3241
T++ +LG ++ NA A+ + +NN
Sbjct 1325 TQRANILSLGSLAI-NAGANAGQTLNN 1350
Score = 59.7 bits (143), Expect = 1e-10
Identities = 170/866 (20%), Positives = 310/866 (36%), Gaps = 135/866 (16%)
Query 2482 LNAGQNIIINSAQGNISATHLQAEAGNNIQIHAQQGNVTLLSAIDDKRESSTSSKKGVAT 2541
L A +NI + QG +A + A NN+QI + ++TL +++ G+
Sbjct 1980 LIAAENISLTEVQGFANAGAISAS--NNLQISMAK-DITL------------NNRCGLLQ 2024
Query 2542 YNNR-QSGYIDQEVAQTTLKAGDT-VDINAAKNIELQANDVQAGNSIYVGNTLMQRQADG 2599
N Q ++ ++ T+ + T + +++ +++ L+ A + GN +QR
Sbjct 2025 AGNHLQLSTLNSDIDLTSARLNATNLQLDSGRDVILRT----ASDQYSSGNGAVQRT--- 2077
Query 2600 SLKAADGSLMPENVTLSTLATKDEQWDEQQKGYRGIVKDIVKATAVGLAGIEALAPGLKA 2659
+ G L N++ + + T + +Q G +I K V G L+ ++
Sbjct 2078 --QTILGPLASLNISNNAVITAQRDFIQQGAGI-----NIGKDLQVNTGGDWLLSTVQRS 2130
Query 2660 PKITVSESTGKRTE-QISQTGSSLKADNVYVGSSGQTTLTSTDITAKNTILLGQKVTLNA 2718
+I+ G T + GS +K + T + A + Q +TL+A
Sbjct 2131 DQISAQYGGGSATSGSLRHLGSEVKVGGALSANVDNLTAVGARVNAGTIDVRAQNITLSA 2190
Query 2719 AEEQ-KITVESTSKETVQG--------LGAKLNKDSIRLGGFVLEDASQSSKTTETTHKL 2769
A + +T S+SK LG++LN + + D + S+ +T L
Sbjct 2191 ATDSLSVTGGSSSKRHTSSVNLYDETLLGSQLNATG-DINLQTVNDITLSASAVQTDGAL 2249
Query 2770 -----GSINTENLKIQGVEGVDILG--QNITATGDTLIDHGRGD-LNVGGYENKTTVEDK 2821
G + + Q E + G + + ++ T + GR L VG + +++
Sbjct 2250 KLAAGGDVTLTSQTEQHDEQRNHTGTKKGLLSSTTTRSEEGRSQTLAVGSMLSAGSID-- 2307
Query 2822 THVETISTEVGVRNAYLDAALALGAVKDAAEAVKQAKDQYSQAQRDYASGKITKEALD-- 2879
V + + V + D + L A ++ + Q + SQ SG ++ +
Sbjct 2308 --VSSQNIAVAGSSVVADKDIRLRAQENLTVSTAQQSESGSQLFEQKKSGLMSTGGIGVF 2365
Query 2880 --DSKANVAMATANLANAQIAVGSAAA----------TAAASSATYGFTIGANGERIETT 2927
S+ T +++ VGS T S G + G + +
Sbjct 2366 IGTSRQKTTDQTQTVSHVGSTVGSLTGNVRLEAGNQLTLHGSDVVAGKDLALTGADVAIS 2425
Query 2928 NTTNTTQGKWQGSTLELNNLTLKSENQDVNVQGSRLTATGTTSFDGTKDLNVTAGTEHSQ 2987
N+ ++ + + LT+ + + +T + T L G + +
Sbjct 2426 AAENSRSQQYTAESKQ-RGLTVALSGPVGSAVNTAVTTAKAAREENTGRLAGLQGVKAAL 2484
Query 2988 QETSSKTNSQSVSYTYGG-----GGSASIGKQTSTSESKSLTYVNSEVTLNKTEGRLNSL 3042
+ Q V GG G S S+G Q S+S+ + S L T G S+
Sbjct 2485 SGVQAVQAGQLVQAQGGGITEMVGVSVSLGSQKSSSQQQQEQTQVSGSAL--TAGNNLSI 2542
Query 3043 NIKGGEVSIQDRGNLQVNNIHVESLQDT----------ASSSNSSRGGSIGGGYGSGSKN 3092
G ++ I + +++ +D SNSSRGGS+G G +
Sbjct 2543 KASGSDILIAGSQLKAGGDTRLDAARDVQLLGAANRQKTDGSNSSRGGSVGVSVGGSGLS 2602
Query 3093 ITASYNQSKGS---SDSAWVNTTSKLLIGNAQNDANLDAMGVKNI-TNIGGVIANANKNA 3148
+ A+ N+ +G+ + W TT +D+ G+ ++ + + A +A
Sbjct 2603 VFANANKGQGNERGDGTFWTETT-------------VDSGGMFSLRSGRDTALTGAQVSA 2649
Query 3149 DGSLTDHKNLNYTGNLELKDLQDHNNNNSSGFNVSTNIGIPQGGSKAASTAPKGSTTIGL 3208
+ D NL L+ QD +N ++ S I +P G AA L
Sbjct 2650 ETVKAD-----VGRNLTLQSQQDRDNYDAKQSRASGGISVPVAGGGAAVNLSMSRDR--L 2702
Query 3209 NSSGQETEQLTKATLGQGSV----------------TNATADTN---------RDINNTQ 3243
+S + T G G V + A AD N DI N
Sbjct 2703 SSQYDSVQAQTGIFAGSGGVDIRVGEHTQLDGAVIASTAAADKNTLDTGTLGFSDIKNKA 2762
Query 3244 EITRDQTTGMLNGSVTVDHRLLSESG 3269
T + G L+ V LLS G
Sbjct 2763 VFTVEHQGGSLSTGGPVGSDLLSNLG 2788
Score = 50.1 bits (118), Expect = 9e-08
Identities = 207/996 (21%), Positives = 369/996 (37%), Gaps = 194/996 (19%)
Query 352 GDLTNTGNLIANQGQLQLNAENIKNTGNISSATS-QVSLHSQ-NLDN-SGLISSADELNI 408
GDL G LIA + + N G IS++ + Q+S+ L+N GL+ + + L +
Sbjct 1972 GDLRANGALIAAENISLTEVQGFANAGAISASNNLQISMAKDITLNNRCGLLQAGNHLQL 2031
Query 409 QQQGHVGNRGTLNAARIVVDAGSLANSGSIEQTGAQALDLKAGSMSNIGGKIGIAKTSST 468
TLN+ + A N+ +++ + + L+ S G + +T +
Sbjct 2032 ---------STLNSDIDLTSA--RLNATNLQLDSGRDVILRTASDQYSSGNGAVQRTQTI 2080
Query 469 GGNGSESGGGSQPV--EPNNAAQDGGSLEVVNTDSTPTTPKTYETGYIHVRDQLNNDQGA 526
G + + V + Q G + + D T + + DQ++ G
Sbjct 2081 LGPLASLNISNNAVITAQRDFIQQGAGIN-IGKDLQVNTGGDWLLSTVQRSDQISAQYGG 2139
Query 527 IVAQGGIDLESNNGLDNQGGQL--NLGRVKIQGERFNNDQGQLTVKQAEIQTNSLSNQSG 584
A G L GG L N+ + G R N G + V+ I ++ ++
Sbjct 2140 GSATSG-SLRHLGSEVKVGGALSANVDNLTAVGARVN--AGTIDVRAQNITLSAATD--- 2193
Query 585 QLISNQKLNIQTQTANNQKGKIQSVDQLDLNVANGLNNIEGQIASGQQLNIQADQVNNQS 644
++ ++ K SV N+ + G QLN D
Sbjct 2194 --------SLSVTGGSSSKRHTSSV------------NLYDETLLGSQLNATGD------ 2227
Query 645 GLIYSEQQGIELKANHAINNTSGIIQAKTQLNLASTQLDNTSGHIQAENIQQQHTTVNNT 704
I L+ + I ++ +Q L LA+ G + + +QH N
Sbjct 2228 ---------INLQTVNDITLSASAVQTDGALKLAA------GGDVTLTSQTEQHDEQRNH 2272
Query 705 QGSIVAGQSLISTVDQFDNHQ-----GLIDAKNIQLTHQVLNNSG-SIYADQNIKITGQH 758
G+ S +T + Q ++ A +I ++ Q + +G S+ AD++I++ Q
Sbjct 2273 TGTKKGLLSSTTTRSEEGRSQTLAVGSMLSAGSIDVSSQNIAVAGSSVVADKDIRLRAQ- 2331
Query 759 ILNTGSIAAGQNIQLNTAKLQHEQAALIAAGLDRQGKLTSTGDLDITAEQTTLHGQSFAG 818
+N+ ++TA+ + L ++ L STG + + F G
Sbjct 2332 ----------ENLTVSTAQQSESGSQLFE---QKKSGLMSTGGIGV-----------FIG 2367
Query 819 QQLKVASKQQIDATNGQLQAKNIDLASDAGDISTRAATVIAEQLSLKSHDLIDNQQGTLS 878
S+Q+ T Q Q + + S G ++ QL+L D++ + L+
Sbjct 2368 -----TSRQK---TTDQTQTVS-HVGSTVGSLTGNVRLEAGNQLTLHGSDVVAGKDLALT 2418
Query 879 AQQLNLTANRLDNTQGHILHTGQDQLDLNFSQSLNNQLGEIRSNAAELNIKTALLNNTEG 938
+ ++A +Q + + Q L + S + + + N A K A NT G
Sbjct 2419 GADVAISAAENSRSQQYTAESKQRGLTVALSGPVGSAV-----NTAVTTAKAAREENT-G 2472
Query 939 QVVHAGTQQL-----NIQTAQLNGHLGHILSNGTLQLKAGTLDVSGGVTSADQITIQANV 993
++ AG Q + +Q Q G L G ++ ++ + +S+ Q Q V
Sbjct 2473 RL--AGLQGVKAALSGVQAVQA-GQLVQAQGGGITEMVGVSVSLGSQKSSSQQQQEQTQV 2529
Query 994 LNNA--QGQLIQRGTSNPLNLTIQQQLNNQAGLIQSATATDIK-AGSLNNQRGTLS-SAQ 1049
+A G + S L QL G + A D++ G+ N Q+ S S++
Sbjct 2530 SGSALTAGNNLSIKASGSDILIAGSQL-KAGGDTRLDAARDVQLLGAANRQKTDGSNSSR 2588
Query 1050 GQNLDVDVAGK----LDNSQSGQ--------------IYAGNQAHLQVGSIDNSHQGQIN 1091
G ++ V V G N+ GQ + +G L+ G Q++
Sbjct 2589 GGSVGVSVGGSGLSVFANANKGQGNERGDGTFWTETTVDSGGMFSLRSGRDTALTGAQVS 2648
Query 1092 AQ-------QNLQLTSQQQINN-QSGQIVANGDVQIQSQGLNNSHGQMGSLQGG--LSLN 1141
A+ +NL L SQQ +N + Q A+G + + G GG ++L+
Sbjct 2649 AETVKADVGRNLTLQSQQDRDNYDAKQSRASGGISVPVAG------------GGAAVNLS 2696
Query 1142 TGSDTLINQSGLIQAKKDIGIQAQRIDNQQGQITTQGQAELISQAEID--NLEGAIAADL 1199
D L +Q +QA+ I + +D + G+ T A + S A D L+
Sbjct 2697 MSRDRLSSQYDSVQAQTGIFAGSGGVDIRVGEHTQLDGAVIASTAAADKNTLDTGTLGFS 2756
Query 1200 DV------NIRSQGLNNNKG------QISSAQGNLTLNAGNGTL---TNQAATIVSGKTL 1244
D+ + QG + + G +S+ G + GNG T QAA VS T+
Sbjct 2757 DIKNKAVFTVEHQGGSLSTGGPVGSDLLSNLGGMVLAGLGNGGYAEGTTQAA--VSEGTI 2814
Query 1245 TLSANQLDNSNHGQINSQNNADISIVKDINNTSGVI 1280
T+ + N Q N D + +D N +G I
Sbjct 2815 TVRDTE---------NQQQNVD-DLSRDTGNANGSI 2840
Score = 42.0 bits (97), Expect = 3e-05
Identities = 68/296 (23%), Positives = 117/296 (40%), Gaps = 36/296 (12%)
Query 2215 GDLKGDGTLLSGNSVNLKLDGDLINGATIAGREALQITADNVQNLNGRIQGNQVAIETQK 2274
G+ +GDGT + +V+ L +G A A Q++A+ V+ GR + +++Q+
Sbjct 2612 GNERGDGTFWTETTVDSGGMFSLRSGRDTALTGA-QVSAETVKADVGR----NLTLQSQQ 2666
Query 2275 DLNNIGG-QIIAKDAMALKVGGNLNIESTTRTSESKVGNFSSSITNVDRVAGLYVGNGST 2333
D +N Q A +++ V G + S S+ SS +V G++ G+G
Sbjct 2667 DRDNYDAKQSRASGGISVPVAGG---GAAVNLSMSR-DRLSSQYDSVQAQTGIFAGSGGV 2722
Query 2334 KQLDPNQATLMLNVAGNSSLKGVQINNSNSATVLNTTGNVDLGTVSVGKQETLKIDDKNG 2393
+ V ++ L G I S +A NT LG + + ++ + G
Sbjct 2723 D----------IRVGEHTQLDGAVIA-STAAADKNTLDTGTLGFSDIKNKAVFTVEHQGG 2771
Query 2394 YQLKQQQDVGSQIKS-AGSLLINGQNITSKAVDLNSQQGDIQLSAQKDIVL--DNGLNQS 2450
L VGS + S G +++ G A +G Q + + + D Q
Sbjct 2772 -SLSTGGPVGSDLLSNLGGMVLAGLGNGGYA------EGTTQAAVSEGTITVRDTENQQQ 2824
Query 2451 TVSSQSQSKGSFGGKKSSTYDASSSTSIANQLN-----AGQNIIINSAQGNISATH 2501
V S+ G+ G +D + ++ GQ + I S QG I ATH
Sbjct 2825 NVDDLSRDTGNANGSIGPIFDKEKEQNRLKEVQLIGEIGGQALDIASTQGKIIATH 2880
Score = 33.9 bits (76), Expect = 0.007
Identities = 172/832 (21%), Positives = 286/832 (34%), Gaps = 154/832 (19%)
Query 2510 IQIHAQQGNVTLLSAIDDKRESSTSSKKGVATYNNRQSGYIDQEVAQTTLKAGDTVDINA 2569
I + AQ V SA +++ + SS G N QT G V NA
Sbjct 62 ISLSAQAAIVADGSAPGNQQPTIISSANGTPQVN-----------IQTPSSGG--VSRNA 108
Query 2570 AKNIELQANDVQAGNSIYVGNTLMQRQADGSLKAADGSLMPENVTLSTLATKDEQWDEQQ 2629
+ ++ V N V T + DG+ A G +V L+ + ++D Q
Sbjct 109 YRQFDVDNRGVILNNGRGVNQTQIAGLVDGNPWLARGEA---SVILNEVNSRDPS---QL 162
Query 2630 KGYRGIVKDIVKATAVGLAGIEALAPG-LKAPKITVSESTGKRTEQISQ-TGSSLKADNV 2687
GY + + AGI G + A + T++ TG+ Q TG ++ +
Sbjct 163 NGYIEVAGRKAQVVIANPAGITCEGCGFINANRATLT--TGQAQLNNGQLTGYDVERGEI 220
Query 2688 YVGSSGQTTLTSTDITAKNTILLGQKVTLNA---AEEQKITVESTSKETVQGLGAKLNKD 2744
+ G + +T L+ + V +NA A E IT T + V +N +
Sbjct 221 VIQGKGLDSRGQD-----HTDLIARSVKVNAGIWANELNIT---TGRNQVDAAHQNINTN 272
Query 2745 SIRLGGFVLEDASQSSKTTETTHKLGSINTENLKIQGVE---GVDILGQNITATGDTLID 2801
+ D LG + +++ G E GV G+ + GD +I
Sbjct 273 AA--------DGRHRPAVAVDVANLGGMYAGKIRLIGTETGVGVHNAGEIGASAGDIVIT 324
Query 2802 HGRGDLNVGGYEN--KTTVEDKTHVETISTEVGVRNAYLDAALAL---GAVKDAAEAVKQ 2856
+N G + + V + +E G N L A L G V A + + +
Sbjct 325 ADGMLVNRGQISSAQQLAVNTPSGIENSGVLYGKGNTQLTTAGKLSNSGTVAAAGDTLIR 384
Query 2857 AKDQYSQAQRDYASG------KITKEALD-DSKANVAMATANLANAQIAVGSAAATAAAS 2909
A + S +G IT+ LD ++ + N++ + + S
Sbjct 385 AAEVNSSRNSVLGAGIKSDNSAITRGTLDIKARGQLTAQGKNISGTAQTFNANRIDLSGS 444
Query 2910 SATYG-FTIGANGERIETTNTTNTTQGKWQGST---LELNNLTLKSENQDVNVQ-----G 2960
G T G I+ T + ST L + L +E ++ Q G
Sbjct 445 QTQSGDLTFTTEGGDIDLTGANLFANRRLSVSTPSLLRTDKANLFAEQIALDAQALANVG 504
Query 2961 SRLTATGTTSF--------DGTKDLNVTAGTEHSQQETSSKTNSQSVSYTYGGGGSASIG 3012
+T TG T F D +T G Q E + +NSQS+ G G S G
Sbjct 505 GVITQTGLTDFNLNLPGDIDNRDGTLLTRGNFLLQAEHLT-SNSQSLL----GAGIQSDG 559
Query 3013 K-------------------QTSTSESKSLTYVNSEVTLNKTEGRLNSLNIKGGEVSIQD 3053
K +T T+ + +L+ ++T + T+ + L G++++
Sbjct 560 KLAPRGDLNVTTRHALIAQGKTLTAGTLALSGSRLDLTDSLTQAKYMRLTATEGDIALTG 619
Query 3054 RGNLQVNNIHVESLQDTASSSNSSRGGSIGGGYGSGSKNITASYNQSKGSSDSAWVNTTS 3113
+ N + ++ Q S I N+TA Y+ S
Sbjct 620 ATVMAANTLFADTRQILRSDKAYLTADQI---------NLTA-YSLSN----------VE 659
Query 3114 KLLIGNAQNDANLDAMGVKNITNIGGVIANANKNADGSLTDHKNLNYTGNLELKDLQDHN 3173
++ D LD G + N GGV+ GNL L+ + +
Sbjct 660 GRVVQKGSGDFRLDLPGY--LDNRGGVLLTK-----------------GNLALQAERLTS 700
Query 3174 NNNSSGFNVSTNIGIPQGGSKAASTAPKGSTTIGLNSSGQETEQLTKATLGQGSVTNATA 3233
N+ S GI GSKA+ + +TT L + GQ + G++T +
Sbjct 701 NSQSL-----LGAGIQADGSKASKGDLQANTTQALIAQGQ--------NVAAGTMT--LS 745
Query 3234 DTNRDINNTQEITRDQTTGMLNGSVTVDHRLLSESGRAEI--VKEQEQLIEN 3283
+ D+ +Q + T +G VT L G + V EQ + N
Sbjct 746 GSRVDLTGSQTHASNITITARDGDVTTREATLITPGTLSMTAVANPEQTLNN 797
>I1WVY3 tRNA nuclease CdiA-2 [Burkholderia pseudomallei (strain
1026b)]
Length=3122
Score = 434 bits (1116), Expect = 3e-124
Identities = 418/1464 (29%), Positives = 658/1464 (45%), Gaps = 217/1464 (15%)
Query 1 MNKNRYRIIFSQARGMFIAVAEIVKSKTKQAGQSQADGHDNKACSASDSDSMGFDSSHLK 60
MNKNRYR++F++ARG + V E ++ + G S S F H+
Sbjct 1 MNKNRYRVVFNRARGALMVVQENGRASHGSGSRDARAGVVPAWLSLSP-----FALRHV- 54
Query 61 KLKQLNFAVISVLGASIFTLPLNTIADSQIIADKGAPTSQQPTILNSSNGVTQVNIQTPS 120
A+ ++ A + + +N +Q++A + P+++ + NG+ QVNI P
Sbjct 55 -------ALAVLVAAGVVPIWVN----AQVVAGG----AHAPSVIQTQNGLQQVNINRPG 99
Query 121 AGGVSRNTYSQFDVGQEGAILNNARNNTQTQLGGWIQGNPWLAKGE-AKVILNEVNSSNP 179
A GVS NTY+QFDV + G ILNN+ N QTQLGG I GNP G+ A++I+N+VNS+NP
Sbjct 100 ASGVSMNTYNQFDVPKPGIILNNSPINVQTQLGGIIGGNPNFQAGDAARLIVNQVNSNNP 159
Query 180 SQLKGYIEVAGKQAQVVIANPSGLVCDGCGVINADRFTLTTGQAVMN-QGYLESFRVREG 238
S ++G +E+ G AQ+VIAN +GLV DG G +N R TLTTG G L F V +G
Sbjct 160 SFIRGKVEIGGAAAQLVIANQAGLVVDGGGFLNTSRATLTTGNPNFGPDGSLTGFNVNQG 219
Query 239 QITIQGKGLNGSLTPFTDVYARALQVNAGLYAKELNVVLGQNDINVNDPTTSNVSPIQSN 298
I++ G GL+ + D+ ARA+Q+NA YAK LNVV G N ++ N T N +PI +N
Sbjct 220 LISVVGAGLDTANVDQVDLLARAVQINAKAYAKTLNVVAGSNQVDYN---TLNATPIAAN 276
Query 299 TSANNKPQFALDVGQLGGMYAGKIFLVGTEQGVGVRNAGSMNSTQSTLTLNANGDLTNTG 358
A P A+DV QLGGMYA ++FLV +E GVGV NAG + + LTL ANG L +G
Sbjct 277 GPA---PTIAIDVSQLGGMYANRVFLVSSENGVGVANAGDIAAQAGDLTLQANGRLVLSG 333
Query 359 NLIANQGQLQLNAE-NIKNTGNISSATSQVSLHSQNLDNSGLISSADELNIQQQGHVGNR 417
+ A G + L+A I+N+G S +L NSG +++ QQ N
Sbjct 334 HTNA-AGNMSLSASGGIQNSGVTYGKQSVTITTGADLTNSGALTA-------QQNLTANV 385
Query 418 GTLNAARIVVDAGSLANSGSIEQTGAQALDLKAGSMSNIGGKIGIAKTSSTGGNGSESGG 477
G+LN+ G+L +++ T + DL S G++ T+S GN + +G
Sbjct 386 GSLNS------TGTLGAGINVDSTVGTSGDLNVTS----SGQLTATGTNSAAGNATFTGS 435
Query 478 GSQPVEPNNAAQDGGSLEVVNTDSTPTTPKTYETGYIHVR--DQLNNDQGAIVAQGGIDL 535
G AA +L D G ++ + + ND+G + + G+ L
Sbjct 436 GVNLSNSATAANGNLALTATAGDVNLAGSTVSAKGAVNAQASGTVVNDRGNLSSGAGMTL 495
Query 536 ESNNGLDNQGGQLN-LGRVKIQ-GERFNNDQGQLTVKQ-AEIQTNSLSNQSGQLISNQKL 592
L NQGG+ N G + +Q +N G L+ + A+++ +++ N +G + S K
Sbjct 496 -GGGSLSNQGGRANSQGPLSVQMAGTVSNQNGMLSSQSTADVRGSAIQNNAGLIQSAGKQ 554
Query 593 NIQTQTANNQKGKIQSV--DQLDLNVANGLNNIEGQIASGQ------------------- 631
I + +N G++ S+ D L + L N G SG
Sbjct 555 TIAGASIDNSAGRLISLNADGLSVTATGALTNAAGANVSGDPGGVIGGKGDVTVQGNTVT 614
Query 632 ---------QLNIQADQVNNQSGLIYSEQQGIELKANHAINNTSGIIQAKTQLNLASTQL 682
L++ V+N +G +++ Q NH ++N G ++ ++ + L L
Sbjct 615 NSGSMSADATLHVIGQSVDNGNGALHAGQTTTVDAGNH-LSNAGGRVEGQSAV-LNGATL 672
Query 683 DNTSGHIQAENIQQQHTTVNNTQGSIV---AGQSLISTVDQFDN-HQGLIDAKNIQL--- 735
DN+ G + A + TT+ N G++ G ++ D DN + GLI ++ L
Sbjct 673 DNSQGTVNAATVSLNGTTLLNHGGTVTQTGTGPMTVAITDTLDNSNNGLIQTRSTDLSLT 732
Query 736 ------------TH-------------QVLNNSGSIYADQNIKITGQHILNTGSIAAGQ- 769
TH V N +G+I ++ + G+ I N+ A+GQ
Sbjct 733 STTLINDNGGTITHVGPGTLTVGNGSGTVSNKAGAIASNGRTVLQGKTIDNSAGSASGQT 792
Query 770 NIQLNTAKLQHEQAALIAAGLDRQGKLTSTGDLDITAEQTTLHGQSFAGQQLKVASKQQI 829
+ +N A ++ G GKLTS ++D+TA ++
Sbjct 793 GLSVNAAD------SITNLG----GKLTSNANVDVTAGGALVN----------------- 825
Query 830 DATNGQLQAKNIDLASDAGDISTRAATVIAEQLSLKSHDLIDN-QQGTLSAQQLNLTANR 888
G+L +K + +S +++ L+ L+DN Q G A QL LTA
Sbjct 826 --DGGELGSKTAATTIHSASLSNLNGKIVSPTLTATVAGLLDNSQNGDFEANQLALTAAN 883
Query 889 LDNTQGHILHTGQDQLDLNFSQSLNNQL-GEIRSNAAELNIKTALLNNTEGQVVHAGTQQ 947
L N GHI L S +L+N G I++N+ +L + A+L+N++G + H GT
Sbjct 884 LKNQGGHISQWQSGPTTLAVSGTLDNSNGGVIQTNSTDLTLAPAVLDNSKGTITHGGTGT 943
Query 948 LNIQTAQLNGHL----GHILSNGTLQLKAGTLDVSGGVTSAD---QITIQANVLNNAQGQ 1000
L + G L G I +NG +KAG+LD GV +A TI A +NN QG
Sbjct 944 LTLTPGNGAGALQNTGGTIGTNGQAIVKAGSLDNGSGVIAAKLGLSATI-AGAMNNTQGL 1002
Query 1001 LIQRGTSNPLNLTIQQQLNNQAGLIQSATATD-----IKAGSLNNQRGTLSSAQGQNLDV 1055
+ ++ L++ L+N G I++ T D I+A S++N G + + V
Sbjct 1003 M---RSNAALSIISNGALSNHQGHIEAGTPGDTSTLSIQAASIDNTDGAVHDFGTGKMTV 1059
Query 1056 DVAGKLDNSQSGQIYAGNQAHLQVGSIDNSHQGQINAQQNLQLTSQQQINNQSGQIVANG 1115
++ NS +G + GQ+ Q ++ + + N Q GQ++
Sbjct 1060 QGGSQIVNSHAGGV---------------DGMGQMTGQGDVTIGAASISNTQGGQLM-GA 1103
Query 1116 DVQIQSQGLNNSHGQMGSLQGGL-SLNTG-SDTLINQSGLIQAKKDIGIQAQRI------ 1167
++ IQ L+NS GQ+G++ +N S + N +G I + +D+ + A +
Sbjct 1104 NLLIQGATLDNSGGQVGNVANATGDVNVAMSGAVTNTNGSITSTRDLSVAASTLLGGGAY 1163
Query 1168 -------DNQQGQITTQGQAEL-ISQAEIDNLEGAIAADLDVNIRS-QGLNNNKGQI--- 1215
N QG TT Q + I + L G A N++S L N G I
Sbjct 1164 SAARDAAINLQGDFTTTPQTQFNIGRDLTFTLPGTFAN--SANLQSVHNLTVNAGNIVNT 1221
Query 1216 -SSAQGNLTLNAGNGTLTNQAATIVSGKTLTLSANQLDNSNHGQINSQNNADIS-----I 1269
+ G+L L+ +G LTN A + + S SN G + +D S +
Sbjct 1222 GAMTAGSL-LSTHSGDLTNYGAMVGGSVAIQASGTV---SNLGPVALIGASDTSGLLEIV 1277
Query 1270 VKDINNTSGVIAAKQQLILSSQGLNNTTGQIGTVQGNLHIDAGSQLLNNQQGRIQSGQDL 1329
DI N + GL G + +A L+NN IQSG +
Sbjct 1278 AHDIENRDDTTLGDSMPTTTIFGLGKVALAGGKDANGNYTNAA--LINNSSAAIQSGASM 1335
Query 1330 NLNATGIDNTQGQI-SSKNQLQLD 1352
L+A + NT+ + +S N Q+D
Sbjct 1336 ELHADKVTNTRRVMQTSGNTSQVD 1359
Score = 384 bits (987), Expect = 4e-109
Identities = 627/2851 (22%), Positives = 1074/2851 (38%), Gaps = 491/2851 (17%)
Query 740 LNNSGSIYADQNIKIT-GQHILNTGSIAAGQNIQLNTAKLQHEQAALIAAGLDRQGKLTS 798
+ NSG Y Q++ IT G + N+G++ A QN+ N L + AG++ + +
Sbjct 349 IQNSGVTYGKQSVTITTGADLTNSGALTAQQNLTANVGSLN--STGTLGAGINVDSTVGT 406
Query 799 TGDLDITAE-QTTLHG-QSFAGQQLKVASKQQIDATNGQLQAK-NIDLASDAGDISTRAA 855
+GDL++T+ Q T G S AG S ++ +N A N+ L + AGD++ +
Sbjct 407 SGDLNVTSSGQLTATGTNSAAGNATFTGSG--VNLSNSATAANGNLALTATAGDVNLAGS 464
Query 856 TVIAE-QLSLKSHDLIDNQQGTLSAQQ-LNLTANRLDNTQGHILHTGQDQLDLNFSQSLN 913
TV A+ ++ ++ + N +G LS+ + L L N G Q L + + +++
Sbjct 465 TVSAKGAVNAQASGTVVNDRGNLSSGAGMTLGGGSLSNQGGRA--NSQGPLSVQMAGTVS 522
Query 914 NQLG--------EIRSNAAELN-----------IKTALLNNTEGQVVHAGTQQLNIQT-- 952
NQ G ++R +A + N I A ++N+ G+++ L++
Sbjct 523 NQNGMLSSQSTADVRGSAIQNNAGLIQSAGKQTIAGASIDNSAGRLISLNADGLSVTATG 582
Query 953 -------AQLNGHLGHILSN-GTLQLKAGTLDVSGGVTSADQITIQANVLNNAQGQLIQR 1004
A ++G G ++ G + ++ T+ SG +++ + + ++N G L
Sbjct 583 ALTNAAGANVSGDPGGVIGGKGDVTVQGNTVTNSGSMSADATLHVIGQSVDNGNGALHAG 642
Query 1005 GTSNPLNLTIQQQLNNQAGLIQSATATDIKAGSLNNQRGTLSSAQGQNLDVDVAGKLDNS 1064
T+ + L+N G ++ +A + +L+N +GT+++A V + G +
Sbjct 643 QTTT---VDAGNHLSNAGGRVEGQSAV-LNGATLDNSQGTVNAAT-----VSLNGTTLLN 693
Query 1065 QSGQIYAGNQAHLQVG---SIDNSHQGQINAQQ-NLQLTSQQQINNQSGQIVANGDVQIQ 1120
G + + V ++DNS+ G I + +L LTS IN+ G I G
Sbjct 694 HGGTVTQTGTGPMTVAITDTLDNSNNGLIQTRSTDLSLTSTTLINDNGGTITHVGP---- 749
Query 1121 SQGLNNSHGQMGSLQGGLSLNTGSDTLINQSGLIQAKKDIGIQAQRIDNQQGQITTQGQA 1180
G L++ GS T+ N++G I + +Q + IDN G + Q
Sbjct 750 ---------------GTLTVGNGSGTVSNKAGAIASNGRTVLQGKTIDNSAGSASGQTGL 794
Query 1181 ELISQAEIDNLEGAIAADLDVNIRSQG-LNNNKGQISSAQGNLTLNAGNGTLTNQAATIV 1239
+ + I NL G + ++ +V++ + G L N+ G++ S T+++ + L+N IV
Sbjct 795 SVNAADSITNLGGKLTSNANVDVTAGGALVNDGGELGSKTAATTIHSAS--LSNLNGKIV 852
Query 1240 SGKTLTLSANQLDNSNHGQINSQNNADISIVKDINNTSGVIAAKQQLILSSQGLNNTTGQ 1299
S A LDNS +G + QL L++ L N G
Sbjct 853 SPTLTATVAGLLDNSQNGDFEAN----------------------QLALTAANLKNQGGH 890
Query 1300 IGTVQGNLHIDAGSQLLNNQQGRI--QSGQDLNLNATGIDNTQGQISSKNQ----LQLDS 1353
I Q A S L+N G + + DL L +DN++G I+ L +
Sbjct 891 ISQWQSGPTTLAVSGTLDNSNGGVIQTNSTDLTLAPAVLDNSKGTITHGGTGTLTLTPGN 950
Query 1354 REQLLNNRQGTLSAENLTI-DSGELNNDQGLIQAQQSIQIDTHQHNLSNTNSGAQGGILS 1412
L N GT+ I +G L+N G+I A+ + ++ + QG + S
Sbjct 951 GAGALQNTGGTIGTNGQAIVKAGSLDNGSGVIAAKLGLSA-----TIAGAMNNTQGLMRS 1005
Query 1413 QGNIQLNNIQTLDNQQGYLASA-----QQLDLQANQVFNQNGTLLAAKQLNLQGTGQNQL 1467
+ + + L N QG++ + L +QA + N +G + + G +Q+
Sbjct 1006 NAALSIISNGALSNHQGHIEAGTPGDTSTLSIQAASIDNTDGAVHDFGTGKMTVQGGSQI 1065
Query 1468 LNNQSGQMLSMGGMNLNIDQINNKGKANTADADSHIMAAGELNITTQQLDNQNTLNTDPA 1527
+N+ +G + MG M T D I AA N QL N L
Sbjct 1066 VNSHAGGVDGMGQM--------------TGQGDVTIGAASISNTQGGQLMGANLL----- 1106
Query 1528 NTSIQGIDANTLNVTSKVLNNQSGVIRSSADQNLNVQQALNNQSGQISSEKQLTLVGDQL 1587
IQG L+N G + + A+ +V A++
Sbjct 1107 ---IQGA----------TLDNSGGQVGNVANATGDVNVAMSGA----------------- 1136
Query 1588 EINNLNGQILAGTALDLIAQSLSGDGKLLSLGNAKLSLQNDYIHSSGAQLQANQDLSLST 1647
+ N NG I + L + A +L G G + +A ++LQ D+ + Q +DL+ +
Sbjct 1137 -VTNTNGSITSTRDLSVAASTLLGGGAYSAARDAAINLQGDFTTTPQTQFNIGRDLTFTL 1195
Query 1648 KGNIINNGTINAGNQLALNAANITNQQAGKIESHDTRLTAQNTLNNTGLINGDFTRLQAE 1707
G N+ + + + L +NA NI N G + + T L N G + G +QA
Sbjct 1196 PGTFANSANLQSVHNLTVNAGNIVN--TGAMTAGSLLSTHSGDLTNYGAMVGGSVAIQAS 1253
Query 1708 -TLNNQGTGRIYGTTLAIQANTLNNQPDSTGTAPVIA----SRGDLHLGVQTLNNLSNPT 1762
T++N G + G + D++G ++A +R D LG
Sbjct 1254 GTVSNLGPVALIGAS------------DTSGLLEIVAHDIENRDDTTLG----------- 1290
Query 1763 DYTSQALIFSAGNLYLGAALDANDYATGQADVIHNESATIESLGDMNLSAKQINNINKYF 1822
D IF G + L DAN T A +I+N SA I+S M L A ++ N +
Sbjct 1291 DSMPTTTIFGLGKVALAGGKDANGNYTNAA-LINNSSAAIQSGASMELHADKVTNTRRVM 1349
Query 1823 KT------------EQVEVSRKDGLEKYCDAWCT----------FDGNYYD--------- 1851
+T +Q+ +S G Y A C+ D NY D
Sbjct 1350 QTSGNTSQVDPALLQQLGIS-MSGCAAYYIAACSGQDVHWINLFHDPNYPDYDPAPIIAA 1408
Query 1852 --------------GNPYEDWMRY--YYSEITYETRTTESAPGQIKAGGHLDLNGAQVV- 1894
G + +Y Y + T T T S QI +GG LD + +
Sbjct 1409 LKLQPGGVFTVPPNGGQWNSGYQYTTYEGKATANTVTKLSPGAQIASGGDLDASTVKTFQ 1468
Query 1895 NDKSQILAGGELKNEGGTIDSGTQIAGIRKIVNTGTQVKYWKYEGQWDNPFENSSET-TF 1953
N S + A G +K G G + T Y+ Y N ++NS T
Sbjct 1469 NYWSSVTAAGNIKQPASLDMDGWGATGQQAPGVTVVYSGYYHY-----NNYDNSEHNWTL 1523
Query 1954 DLSISQALGNQNLNQNQLSTVAVSNNQSAEHIQNSQTTQQEINGLQTSNNNTQLNQTKDV 2013
+G Q + V S +++ I+G S NNT N T
Sbjct 1524 PFGDKPFVGGPG-GYTQAAPADV-RQYSLPDYRSTWGANGTISGNGVSVNNTAANAT--- 1578
Query 2014 DLDQLNLKDSQSQNAPQASAVE---TVQQQSATSAPSSTPQGTSEEIRSID----FSNIK 2066
+ L L Q+ V + Q A + TP I S SN+
Sbjct 1579 -IPSLGLLPGQAVPGLTIGTVSGNASGTQSGAAAIKGGTPTWVDPVIASATAVNVLSNLT 1637
Query 2067 VPNSALYKVNADSKAGYLIETDPAFADYKKWLSSDYMLDALGLDPALQQKRLGDGFYEQR 2126
+P LY+ N+ YLIET+PAF +LSSDY L+ +G++P +KRLGDGFYEQ+
Sbjct 1638 IPQGGLYRPNSAPNPTYLIETNPAFTRMNNFLSSDYYLNQIGVNPLTTEKRLGDGFYEQQ 1697
Query 2127 LVQDQIANLTGYRFLEGFANDDEQYKALMNNGITFAKLYGLRPGIALTAAQTAQLTSDIV 2186
LV++Q+ LTG L + + Y++LM G ++K L G++L+A Q A LT++++
Sbjct 1698 LVRNQVTQLTGKAVLGPYTDLQGMYQSLMLAGAEWSKSLNLPLGMSLSAQQVAALTTNVI 1757
Query 2187 WLVEQSVTLPDGTITKALVPQVYVKVRVGDLKGDGTLLSGNSVNLKLDGDLINGATIAGR 2246
+ ++V + LVP VY+ + +G L++ +++LK N T+
Sbjct 1758 IMQTETV-----GGQQVLVPVVYL-AKADQQNANGPLITAGNIDLKNTQVFTNSGTVKAD 1811
Query 2247 EALQITADNVQNLNGRIQ-----------------------------GNQVAIETQKDLN 2277
L + + N G +Q GN++ ++T
Sbjct 1812 TTLALQGKQIDNAFGALQSGGLTSLDTTGNVDLTSANVKAGSLDLNAGNKLILDTATQTT 1871
Query 2278 ---------------------NIGGQIIAK-------DAMALKVGGNLNIE-------ST 2302
N+ G K +A L VGGNLN
Sbjct 1872 HQVSRDGATSDKTTLGPAANLNVAGDASIKTGGDFQQNAGNLNVGGNLNANIGGNWNLGV 1931
Query 2303 TRTSESKVGNFSSSITNVDRVAGLYVGNGSTKQLDPNQATLMLNVAGNSSLKGVQINNSN 2362
+T E KV ++ +++ D L GST + A + V G+ + +G +++
Sbjct 1932 QQTGEHKVVQRANGVSDTD----LNSATGSTVNVGGKSA---IGVGGDLTAQGARLDFGQ 1984
Query 2363 SATVLNTTGNVDLGTVSVGKQETLKIDDKNGYQL-------KQQQDVGSQIKSAGSL-LI 2414
TV GNV G S G + Q G+ +K +L ++
Sbjct 1985 GGTVA-AKGNVTFGAASTTSTINANSSGDQGNRSYAETRHGSDQALTGTTVKGGDTLNVV 2043
Query 2415 NGQNITSKAVDLNSQQGDIQLSAQKDIVLDNGLNQSTVSSQ---SQSKGSFGGKKSSTYD 2471
+G++I ++ ++GD L A D+ + + +S+ S+S G K +S+ D
Sbjct 2044 SGKDINVIGSTIDLKKGDANLLAAGDVNVGAVTERHVYNSRETHSRSGVVSGTKIASSQD 2103
Query 2472 ASSSTSIANQLNA-----GQNIIINSAQGNISATH-LQAEAGNNIQIHAQQGNVTLLSAI 2525
A+S+ + + ++A G IN + TH + A +++ I Q T S+
Sbjct 2104 ATSTVANGSLISADGVSIGSGKDINVQGSTVVGTHDVALNAAHDVNITTSQD--TSQSST 2161
Query 2526 DDKRESSTSSKKGVATYNNRQSGYIDQEVAQTTLKAGDTV-------DINAAKNIELQAN 2578
+ + S G +++ S Q + + TV +NA + ++ +
Sbjct 2162 TYQEQHSGLMSGGGLSFSVGNSKLAQQNQSSSVTNNASTVGSVDGNLTVNAGNTLHVKGS 2221
Query 2579 DVQAGNSI--YVGNTLMQRQADGSLKAADGSLMPENVTL---------------STLATK 2621
D+ AG + N ++ D + +A +T+ T A +
Sbjct 2222 DLVAGKDVTGTAANIVVDSATDTTRQAQQQQTSKSGLTVGLSGSVGDAINNAISETQAAR 2281
Query 2622 DEQWDEQQKGYRGIVKDIVKATAVGLAGIEAL-----APGLKAPKITVSESTG------- 2669
+ D G + I A V G+ A A G +AP I V S G
Sbjct 2282 ESAKD--SNGRASALHSIAAAGDVAFGGLGAKALLDGAKGPQAPSIGVQVSVGSSHSSMQ 2339
Query 2670 KRTEQISQTGSSLKADN----VYVGS----SGQTTLTSTDITAKNTILL--GQKVTLNAA 2719
+Q Q GSS+ A + G+ G T+ +++ A N L+ Q +N
Sbjct 2340 SSEDQTIQRGSSINAGGNAKLIATGNGTPKDGNITIAGSNVNAANVALIANNQVNLVNTT 2399
Query 2720 EEQKITVESTSKETVQGLGAKLNKDSIRLGGFVLE---DASQSSKTTETTHKLGSINTEN 2776
+ K +S++ + +G + + I + + D + + TH + + T
Sbjct 2400 DTDK--TQSSNSSSGSSVGVSIGTNGIGVSASMQRAHGDGNSDAAIQNNTH-INASQTAT 2456
Query 2777 LKIQGVEGVDILGQNITATGDTLIDHGRGDLNVGGYENKTTVEDKTHVE------TISTE 2830
+ G +++G N+ A + D G G+LNV ++ T H TIS
Sbjct 2457 IVSGG--DTNVIGANVNA-NKVVADVG-GNLNVASVQDTTV--SAAHQSSAGGGFTISQT 2510
Query 2831 VG-----VRNAYLDAALA-----------LGAVKDAAEAVKQAKDQYSQAQRDYASGKIT 2874
G +N + D A G + K Y + D + +T
Sbjct 2511 GGGASFSAQNGHADGNYAGVNEQAGIQAGSGGFDVTVKGNTDLKGAYIASTADASKNSLT 2570
Query 2875 KEALDDSK-ANVAMATANLANAQIAVGSAAATAAASSATYGFTIGANGERIETTNTTNTT 2933
L S N + +AN A +T A ++ + G + + +
Sbjct 2571 TGTLTTSDIENHSHYSANSAGFSAGASVGVSTKAVGPSSVSGSGGVTPMVFQNDSGDQSA 2630
Query 2934 QGKWQGSTLELNNLTLKSENQDV---NVQGSRLTATGTTSFDGTKDLNVTAGTEHSQQET 2990
K S +N + QDV N + L T + + D K L+ A T ++ Q
Sbjct 2631 TTKSAVSAGAINITKPGEQTQDVANLNRDATNLNGTVSKTPDVQKMLSQQADTMNAAQ-A 2689
Query 2991 SSKTNSQSVSYTYGGGGSASIGKQTSTSESKSLTYVNSEVTLNKT--EGRLNSLNIK--- 3045
+ +T SQ + G +I + E L + S + K+ EG + ++
Sbjct 2690 AGQTVSQGIGLYADGKRKDAIDAAKAAYERGDLVAMQSYIDQAKSWDEGGASRAGLQATG 2749
Query 3046 --------GGEV--SIQDRGNLQVNNIHVESLQDTASSSNSSRGGS------------IG 3083
GG V +I +++ + + S G S +G
Sbjct 2750 GALIGGLGGGSVLTAIGGAAGAGTSSLLAGQAEKISKSVGDMTGSSLVGNIAANVAATVG 2809
Query 3084 GGYGSGSKNITASYNQSKGSSDSAWVNTTSKLLIGNAQNDAN----LDAMGVKNITNIGG 3139
G GS + N ++ + T + I Q N A G+ I N
Sbjct 2810 GALVGGSAGAAMASNVELYNAGNDPQKTDDRATIAGLQGLLNQAVAAGAKGLSTIANARN 2869
Query 3140 VIANANKNADGSLTDHKNLNYTGNLELKDLQDHNNNNSSGFNVSTNIGIPQGGSKAASTA 3199
I NA A S D + E K Q S G N + GSK
Sbjct 2870 AIGNAISGALDSAADQFGTLMKRDAEGKMSQSPAELVSQGVANGINTVL---GSKGGEPP 2926
Query 3200 PKGSTTIGLNS-SGQETEQLTKATLGQGSVTNATADTNRDINNTQ--------EITRDQT 3250
G + + ++S +GQ AT +++N D N+TQ + +
Sbjct 2927 LAGPSAVAVDSLTGQAANAALGATDRTPPSNAILSNSNSDNNSTQGSQSGTVTKTPNPEA 2986
Query 3251 TGMLNGSVTVDHRLLSESGRAEIVKEQEQLI 3281
TG L+G T L E +++E + +
Sbjct 2987 TGSLSGKPTQIPPLSDEVTTRSLIRENQSAV 3017
Score = 209 bits (533), Expect = 4e-56
Identities = 337/1386 (24%), Positives = 533/1386 (38%), Gaps = 192/1386 (14%)
Query 257 VYARALQVNAGLYAKE-LNVVLGQNDINVNDPTTSNVSPIQSNTSANNKPQFALDVG--- 312
++ A V G +A + G +N+N P S VS N KP L+
Sbjct 67 IWVNAQVVAGGAHAPSVIQTQNGLQQVNINRPGASGVSMNTYNQFDVPKPGIILNNSPIN 126
Query 313 ---QLGGMYAGKI-FLVGTEQGVGVRNAGSMNSTQSTLTLNANGDLTNTGNLIANQGQLQ 368
QLGG+ G F G + V S N + + G +IANQ L
Sbjct 127 VQTQLGGIIGGNPNFQAGDAARLIVNQVNSNNPSFIRGKVEIGGAAAQL--VIANQAGLV 184
Query 369 LNAENIKNTGNISSATSQV------SLHSQNLDNSGLIS----SADELNIQQQGHVGNRG 418
++ NT + T SL N+ N GLIS D N+ Q +
Sbjct 185 VDGGGFLNTSRATLTTGNPNFGPDGSLTGFNV-NQGLISVVGAGLDTANVDQVDLLARAV 243
Query 419 TLNAARIVVDAGSLANSGSIEQTGAQALDLKAGS--------MSNIGGKIG--IAKTSST 468
+NA +A S ++ A + A +S +GG + SS
Sbjct 244 QINAKAYAKTLNVVAGSNQVDYNTLNATPIAANGPAPTIAIDVSQLGGMYANRVFLVSSE 303
Query 469 GGNGSESGGGSQPVEPNNAAQDGGSLEVVNTDSTPTTPKTYETGYIHVRDQLNNDQGAIV 528
G G + G + Q G L + G
Sbjct 304 NGVGVANAGDIAAQAGDLTLQANGRLVL---------------------------SGHTN 336
Query 529 AQGGIDLESNNGLDNQGGQLNLGRVKIQGERFNNDQGQLTVKQAEIQTNSLSNQSGQLIS 588
A G + L ++ G+ N G V I + G LT +Q N +G L +
Sbjct 337 AAGNMSLSASGGIQNSGVTYGKQSVTITTGADLTNSGALTAQQNLTANVGSLNSTGTLGA 396
Query 589 NQKLNIQTQTANNQKGKIQSVDQLDLNVANGLNNIEGQIA---SGQQLNIQADQVN---- 641
+N+ + + + S QL A G N+ G SG L+ A N
Sbjct 397 G--INVDSTVGTSGDLNVTSSGQL---TATGTNSAAGNATFTGSGVNLSNSATAANGNLA 451
Query 642 --------NQSGLIYSEQQGIELKANHAINNTSGIIQAKTQLNLASTQLDNTSGHIQAEN 693
N +G S + + +A+ + N G + + + L L N G ++
Sbjct 452 LTATAGDVNLAGSTVSAKGAVNAQASGTVVNDRGNLSSGAGMTLGGGSLSNQGGRANSQG 511
Query 694 --IQQQHTTVNNTQGSIVAGQSLISTVDQFDNHQGLIDAKNIQLTHQVLNNSGSIYADQN 751
Q TV+N G + S ST D + IQ NN+G I +
Sbjct 512 PLSVQMAGTVSNQNGML----SSQSTAD--------VRGSAIQ------NNAGLIQSAGK 553
Query 752 IKITGQHILNTGSIAAGQNIQLNTAKLQHEQAALI--AAGL----DRQGKLTSTGDLDIT 805
I G I N+ AG+ I LN L + AAG D G + GD+ +
Sbjct 554 QTIAGASIDNS----AGRLISLNADGLSVTATGALTNAAGANVSGDPGGVIGGKGDVTVQ 609
Query 806 AEQTTLHGQSFAGQQLKVASKQQIDATNGQLQAKNIDLASDAGDISTRAATVIAEQLSLK 865
T G A L V Q +D NG L A DAG+ + A + Q ++
Sbjct 610 GNTVTNSGSMSADATLHVIG-QSVDNGNGALHAGQTTTV-DAGNHLSNAGGRVEGQSAVL 667
Query 866 SHDLIDNQQGTLSAQQLNLTANRLDNTQGHILHTGQDQLDLNFSQSLNNQL-GEIRSNAA 924
+ +DN QGT++A ++L L N G + TG + + + +L+N G I++ +
Sbjct 668 NGATLDNSQGTVNAATVSLNGTTLLNHGGTVTQTGTGPMTVAITDTLDNSNNGLIQTRST 727
Query 925 ELNI-KTALLNNTEGQVVHAGTQQLNIQTAQ--LNGHLGHILSNGTLQLKAGTLDVSGGV 981
+L++ T L+N+ G + H G L + ++ G I SNG L+ T+D S G
Sbjct 728 DLSLTSTTLINDNGGTITHVGPGTLTVGNGSGTVSNKAGAIASNGRTVLQGKTIDNSAGS 787
Query 982 TSADQ-ITIQA-NVLNNAQGQLIQRGTSNP-LNLTIQQQLNNQAGLIQSATA-TDIKAGS 1037
S +++ A + + N G+L TSN +++T L N G + S TA T I + S
Sbjct 788 ASGQTGLSVNAADSITNLGGKL----TSNANVDVTAGGALVNDGGELGSKTAATTIHSAS 843
Query 1038 LNNQRGTLSSAQGQNLDVDVAGKLDNSQSGQIYAGNQAHLQVGSIDNS--HQGQINAQQN 1095
L+N G + S L VAG LDNSQ+G A NQ L ++ N H Q +
Sbjct 844 LSNLNGKIVSP---TLTATVAGLLDNSQNGDFEA-NQLALTAANLKNQGGHISQWQSGPT 899
Query 1096 LQLTSQQQINNQSGQIVANG-DVQIQSQGLNNS-----HGQMGSLQGGLSLNTGSDTLIN 1149
S N+ G I N D+ + L+NS HG G+L L+ G+ L N
Sbjct 900 TLAVSGTLDNSNGGVIQTNSTDLTLAPAVLDNSKGTITHGGTGTLT--LTPGNGAGALQN 957
Query 1150 QSGLIQAKKDIGIQAQRIDNQQGQITTQGQAELISQAEIDNLEGAIAADLDVNIRSQG-L 1208
G I ++A +DN G I + ++N +G + ++ ++I S G L
Sbjct 958 TGGTIGTNGQAIVKAGSLDNGSGVIAAKLGLSATIAGAMNNTQGLMRSNAALSIISNGAL 1017
Query 1209 NNNKGQISSAQGNLTLNAGNGTLTNQAATIVS----------GKTLTLSANQLDNSNHGQ 1258
+N++G I + T TL+ QAA+I + GK +Q+ NS+ G
Sbjct 1018 SNHQGHIEAGTPGDT-----STLSIQAASIDNTDGAVHDFGTGKMTVQGGSQIVNSHAGG 1072
Query 1259 INSQNN----ADISI-VKDINNTSGVIAAKQQLILSSQGLNNTTGQIGTVQ---GNLHID 1310
++ D++I I+NT G L++ L+N+ GQ+G V G++++
Sbjct 1073 VDGMGQMTGQGDVTIGAASISNTQGGQLMGANLLIQGATLDNSGGQVGNVANATGDVNV- 1131
Query 1311 AGSQLLNNQQGRIQSGQDLNLNATGI-------------DNTQGQISSKNQLQLDSREQL 1357
A S + N G I S +DL++ A+ + N QG ++ Q Q + L
Sbjct 1132 AMSGAVTNTNGSITSTRDLSVAASTLLGGGAYSAARDAAINLQGDFTTTPQTQFNIGRDL 1191
Query 1358 LNNRQGTL-------SAENLTIDSGELNNDQGLIQAQQSIQIDTHQHNLSNTNSGAQGGI 1410
GT S NLT+++G + N + + TH +L+N + G +
Sbjct 1192 TFTLPGTFANSANLQSVHNLTVNAGNIVNTGAMTAGSL---LSTHSGDLTNYGAMVGGSV 1248
Query 1411 LSQGNIQLNNIQTLDNQQGYLASAQQLDLQANQVFNQNGTLLAAKQ--LNLQGTGQNQLL 1468
Q + ++N+ + G ++ L++ A+ + N++ T L + G G+ L
Sbjct 1249 AIQASGTVSNLGPVA-LIGASDTSGLLEIVAHDIENRDDTTLGDSMPTTTIFGLGKVALA 1307
Query 1469 NNQSGQMLSMGGMNLNIDQINNKGKANTADADSHIMAAGELNITTQQLDNQNTLNTDPAN 1528
+ G N INN A + A + A N + NT DPA
Sbjct 1308 GGKDAN-----GNYTNAALINNSSAAIQSGASMELHADKVTNTRRVMQTSGNTSQVDPAL 1362
Query 1529 TSIQGI 1534
GI
Sbjct 1363 LQQLGI 1368
Score = 100 bits (250), Expect = 4e-23
Identities = 209/995 (21%), Positives = 366/995 (37%), Gaps = 158/995 (16%)
Query 689 IQAENIQQQHTTVNNTQGSIVAGQSLISTV------DQFDNHQGLIDAKNIQLTH-QVLN 741
+ A+ + T V Q V GQ ++ V DQ + + LI A NI L + QV
Sbjct 1744 LSAQQVAALTTNVIIMQTETVGGQQVLVPVVYLAKADQQNANGPLITAGNIDLKNTQVFT 1803
Query 742 NSGSIYADQNIKITGQHILNT-GSIAAGQNIQLNTAKLQHEQAALIAAGLDRQGKLTSTG 800
NSG++ AD + + G+ I N G++ +G L+T TG
Sbjct 1804 NSGTVKADTTLALQGKQIDNAFGALQSGGLTSLDT-----------------------TG 1840
Query 801 DLDITAEQTTLHGQSFAGQQLKVASKQQID-ATNGQLQAKNIDLASDAGDISTRAATVIA 859
++D+T+ L +K +D AT Q SD + A +A
Sbjct 1841 NVDLTSANVKA-----GSLDLNAGNKLILDTATQTTHQVSRDGATSDKTTLGPAANLNVA 1895
Query 860 EQLSLKSHDLIDNQQGTLSAQQLNLTANRLDNTQGHILHTGQDQL----------DLNFS 909
S+K+ G L+ NL AN N + TG+ ++ DLN +
Sbjct 1896 GDASIKTGGDFQQNAGNLNVGG-NLNANIGGNWNLGVQQTGEHKVVQRANGVSDTDLNSA 1954
Query 910 QSLNNQLG---------EIRSNAAELNIKTALLNNTEGQVVHAGTQQLNIQTAQLNGHLG 960
+G ++ + A L+ +G V + A +G G
Sbjct 1955 TGSTVNVGGKSAIGVGGDLTAQGARLDFGQGGTVAAKGNVTFGAASTTSTINANSSGDQG 2014
Query 961 HI----LSNGTLQLKAGTLDVSGG----VTSADQITIQANVLNNAQGQ--LIQRGTSNPL 1010
+ +G+ Q GT V GG V S I + + ++ +G L+ G N
Sbjct 2015 NRSYAETRHGSDQALTGTT-VKGGDTLNVVSGKDINVIGSTIDLKKGDANLLAAGDVNVG 2073
Query 1011 NLTIQQQLNNQAGLIQSATATDIKAGSLNNQRGTLSSAQGQNLDVDVAGKLDNSQSGQIY 1070
+T + N++ +S + K S + T+++ G L ++ I
Sbjct 2074 AVTERHVYNSRETHSRSGVVSGTKIASSQDATSTVAN-----------GSLISADGVSIG 2122
Query 1071 AGNQAHLQVGSIDNSHQGQINAQQNLQLTSQQQINNQS-------GQIVANGDV------ 1117
+G ++Q ++ +H +NA ++ +T+ Q + S +++ G +
Sbjct 2123 SGKDINVQGSTVVGTHDVALNAAHDVNITTSQDTSQSSTTYQEQHSGLMSGGGLSFSVGN 2182
Query 1118 -----QIQSQGLNNSHGQMGSLQGGLSLNTGSDTLINQSGLIQAKKDIGIQAQRIDNQQG 1172
Q QS + N+ +GS+ G L++N G+ + S L+ K G A + +
Sbjct 2183 SKLAQQNQSSSVTNNASTVGSVDGNLTVNAGNTLHVKGSDLVAGKDVTGTAANIVVDSAT 2242
Query 1173 QITTQGQAELISQAEID-NLEGAIAADLDVNIRSQGLNNNKGQISSAQGNLTLNAGNGTL 1231
T Q Q + S++ + L G++ +NN + +A+ + + G +
Sbjct 2243 DTTRQAQQQQTSKSGLTVGLSGSV---------GDAINNAISETQAARESAKDSNGRASA 2293
Query 1232 TNQAATIVSGKTLTLSANQLDNSNHGQINSQNNADISIVKDINNTSGVIAAKQQLILSSQ 1291
+ A L A L + G +S+ ++ S + +++ Q I
Sbjct 2294 LHSIAAAGDVAFGGLGAKALLDGAKGPQAPSIGVQVSVG---SSHSSMQSSEDQTIQRGS 2350
Query 1292 GLNN-------TTGQIGTVQGNLHIDAGSQLLNNQQGRIQSGQDLNLNATGIDNTQGQIS 1344
+N TG GN+ I AGS + I + Q +N T D TQ S
Sbjct 2351 SINAGGNAKLIATGNGTPKDGNITI-AGSNVNAANVALIANNQVNLVNTTDTDKTQSSNS 2409
Query 1345 SKNQLQLDSREQLLNNRQGTLSAENLTIDSGELNNDQGLIQAQQSIQIDTHQHNLSNTNS 1404
S + G N S + G + +IQ +TH N S T +
Sbjct 2410 SS------------GSSVGVSIGTNGIGVSASMQRAHGDGNSDAAIQNNTH-INASQTAT 2456
Query 1405 GAQGGILS--QGNIQLN--------NIQTLDNQQGYLASAQQLDLQANQVFNQNGTLLAA 1454
GG + N+ N N+ Q +++A Q +Q G +
Sbjct 2457 IVSGGDTNVIGANVNANKVVADVGGNLNVASVQDTTVSAAHQSSAGGGFTISQTGGGASF 2516
Query 1455 KQLNLQGTGQNQLLNNQSGQMLSMGGMNLNI-DQINNKGK--ANTADADSHIMAAGELNI 1511
N G +N Q+G GG ++ + + KG A+TADA + + G L
Sbjct 2517 SAQNGHADGNYAGVNEQAGIQAGSGGFDVTVKGNTDLKGAYIASTADASKNSLTTGTL-- 2574
Query 1512 TTQQLDNQNTLNTDPANTSI-QGIDANTLNVTSKVLNNQSGVI-----RSSADQNLNVQQ 1565
TT ++N + + + A S + +T V ++ GV S DQ+ +
Sbjct 2575 TTSDIENHSHYSANSAGFSAGASVGVSTKAVGPSSVSGSGGVTPMVFQNDSGDQSATTKS 2634
Query 1566 ALNNQSGQISSEKQLTLVGDQLEIN----NLNGQI 1596
A++ +G I+ K D +N NLNG +
Sbjct 2635 AVS--AGAINITKPGEQTQDVANLNRDATNLNGTV 2667
Score = 83.6 bits (205), Expect = 7e-18
Identities = 241/1168 (21%), Positives = 429/1168 (37%), Gaps = 145/1168 (12%)
Query 2166 GLRPGIALTAAQTAQLTSDIVWLV--EQSVTLPDGTITKALVPQVYVKVRVGDLKGDGTL 2223
G P IA+ +Q + ++ V+LV E V + + A + ++ G L G
Sbjct 277 GPAPTIAIDVSQLGGMYANRVFLVSSENGVGVANAGDIAAQAGDLTLQAN-GRLVLSGHT 335
Query 2224 LSGNSVNLKLDGDLINGATIAGREALQITADNVQNLNGRIQGNQVAIETQKDLNNIGGQI 2283
+ +++L G + N G++++ IT +G + Q LN+ G
Sbjct 336 NAAGNMSLSASGGIQNSGVTYGKQSVTITTGADLTNSGALTAQQNLTANVGSLNSTG--- 392
Query 2284 IAKDAMALKVGGNLNIESTTRTSESKVGNFSSSITNVDRVAGLYVGNGSTKQLDPNQATL 2343
+G +N++ST TS S +T AT
Sbjct 393 --------TLGAGINVDSTVGTSGDLNVTSSGQLT----------------------ATG 422
Query 2344 MLNVAGNSSLKGVQINNSNSATVLN-------TTGNVDLGTVSVGKQETLKIDDKNGYQL 2396
+ AGN++ G +N SNSAT N T G+V+L +V + + +G +
Sbjct 423 TNSAAGNATFTGSGVNLSNSATAANGNLALTATAGDVNLAGSTVSAKGAVNA-QASGTVV 481
Query 2397 KQQQDVGSQIKSAGSLLINGQNITSKAVDLNSQQGDIQLSAQKDIVLDNGL--NQSTVSS 2454
+ + S + + G +++++ NS QG + + + NG+ +QST
Sbjct 482 NDR----GNLSSGAGMTLGGGSLSNQGGRANS-QGPLSVQMAGTVSNQNGMLSSQSTADV 536
Query 2455 Q-SQSKGSFGGKKSSTYDASSSTSIANQLNAGQNIIINSAQGNISAT-HLQAEAGNNIQ- 2511
+ S + + G +S+ + SI N +AG+ I +N+ +++AT L AG N+
Sbjct 537 RGSAIQNNAGLIQSAGKQTIAGASIDN--SAGRLISLNADGLSVTATGALTNAAGANVSG 594
Query 2512 ----IHAQQGNVTLLSAIDDKRESSTSSKKGVATYNNRQSGYIDQEV--AQTTLKAGDTV 2565
+ +G+VT + +++ S AT + I Q V L AG T
Sbjct 595 DPGGVIGGKGDVT----VQGNTVTNSGSMSADATLH-----VIGQSVDNGNGALHAGQTT 645
Query 2566 DINAAKNIELQANDVQAGNSIYVGNTLMQRQADGSLKAADGSLMPENVTLSTLATKDEQW 2625
++A ++ V+ +++ G TL Q G++ AA SL +TL
Sbjct 646 TVDAGNHLSNAGGRVEGQSAVLNGATLDNSQ--GTVNAATVSL-----NGTTLLNHGGTV 698
Query 2626 DEQQKGYRGI-VKDIVKATAVGLAGIEALAPGLKAPKITVSESTGKRTEQISQTGSSLKA 2684
+ G + + D + + GL I+ + L T+ G T + +
Sbjct 699 TQTGTGPMTVAITDTLDNSNNGL--IQTRSTDLSLTSTTLINDNG-------GTITHVGP 749
Query 2685 DNVYVGSSGQTTLTSTDITAKN--TILLGQKVTLNAAEEQKIT-VESTSKETVQGLGAKL 2741
+ VG+ T A N T+L G+ + +A T + + +++ LG KL
Sbjct 750 GTLTVGNGSGTVSNKAGAIASNGRTVLQGKTIDNSAGSASGQTGLSVNAADSITNLGGKL 809
Query 2742 NKDS---IRLGGFVLEDASQ-SSKTTETTHKLGSINTENLKIQGVEGVDILGQNITATGD 2797
++ + GG ++ D + SKT TT S++ N K I+ +TAT
Sbjct 810 TSNANVDVTAGGALVNDGGELGSKTAATTIHSASLSNLNGK--------IVSPTLTATVA 861
Query 2798 TLIDHGRGDLNVGGYENKTTVEDKTHVETISTEVGVRNAYLDAALALGAVKDAAEAVKQA 2857
L+D+ + G +E +++ + + G + ++ V Q
Sbjct 862 GLLDNSQN----GDFEANQLALTAANLKNQGGHISQWQSGPTTLAVSGTLDNSNGGVIQT 917
Query 2858 KD---QYSQAQRDYASGKIT---KEALDDSKANVAMATANLANAQIAVGSAAATAAASSA 2911
+ A D + G IT L + N A A N G A A +
Sbjct 918 NSTDLTLAPAVLDNSKGTITHGGTGTLTLTPGNGAGALQNTGGTIGTNGQAIVKAGSLDN 977
Query 2912 TYGFTIGANGERIETTNTTNTTQGKWQGSTL--ELNNLTLKS-----------ENQDVNV 2958
G G N TQG + + ++N L + + +++
Sbjct 978 GSGVIAAKLGLSATIAGAMNNTQGLMRSNAALSIISNGALSNHQGHIEAGTPGDTSTLSI 1037
Query 2959 QGSRLTATGTTSFD-GTKDLNVTAGTEHSQQETSSKTNSQSVSYTYGGG----GSASIGK 3013
Q + + T D GT + V G SQ S + G G G+ASI
Sbjct 1038 QAASIDNTDGAVHDFGTGKMTVQGG---SQIVNSHAGGVDGMGQMTGQGDVTIGAASI-S 1093
Query 3014 QTSTSESKSLTYVNSEVTLNKTEGRLNSLNIKGGEVSIQDRGNLQVNNIHVESLQDTASS 3073
T + + TL+ + G++ ++ G+V++ G + N + S +D + +
Sbjct 1094 NTQGGQLMGANLLIQGATLDNSGGQVGNVANATGDVNVAMSGAVTNTNGSITSTRDLSVA 1153
Query 3074 SNSSRGGSIGGGYGSGSKNITASYNQSKGSSDSAWVNTTSKLLIGNAQNDANLDAMGVKN 3133
+++ GG + N+ + + + + + T L G N ANL + V N
Sbjct 1154 ASTLLGGGAYSAARDAAINLQGDFTTTPQTQFNIGRDLTF-TLPGTFANSANLQS--VHN 1210
Query 3134 ITNIGGVIANANKNADGSL--TDHKNLNYTGNLELKDLQDHNNNNSSGFNVSTNIGIPQG 3191
+T G I N GSL T +L G + + + S IG
Sbjct 1211 LTVNAGNIVNTGAMTAGSLLSTHSGDLTNYGAMVGGSVAIQASGTVSNLGPVALIGASDT 1270
Query 3192 GS----KAASTAPKGSTTIGLNSSGQETEQLTKATLGQGSVTNATADTNRDINNTQEITR 3247
A + TT+G + L K L G N INN+ +
Sbjct 1271 SGLLEIVAHDIENRDDTTLGDSMPTTTIFGLGKVALAGGKDANGNYTNAALINNSSAAIQ 1330
Query 3248 DQTTGMLNG-SVTVDHRLLSESGRAEIV 3274
+ L+ VT R++ SG V
Sbjct 1331 SGASMELHADKVTNTRRVMQTSGNTSQV 1358
Score = 75.5 bits (184), Expect = 2e-15
Identities = 186/838 (22%), Positives = 306/838 (37%), Gaps = 107/838 (13%)
Query 2657 LKAPKITVSESTGKRTEQISQTGSSLKADNVY--VGSSGQTTLTST---DITAKNT---- 2707
LK ++ + T K ++ G + DN + + S G T+L +T D+T+ N
Sbjct 1796 LKNTQVFTNSGTVKADTTLALQGKQI--DNAFGALQSGGLTSLDTTGNVDLTSANVKAGS 1853
Query 2708 --ILLGQKVTLNAAEEQKITVE---STSKETVQGLGAKLN---KDSIRLGGFVLEDASQS 2759
+ G K+ L+ A + V +TS +T G A LN SI+ GG ++A
Sbjct 1854 LDLNAGNKLILDTATQTTHQVSRDGATSDKTTLGPAANLNVAGDASIKTGGDFQQNAGNL 1913
Query 2760 SKTTETTHKLGSI-------NTENLKIQGVEGVDILGQNITATGDTLIDHGRGDLNVGGY 2812
+ +G E+ +Q GV N +ATG T+ G+ + VGG
Sbjct 1914 NVGGNLNANIGGNWNLGVQQTGEHKVVQRANGVSDTDLN-SATGSTVNVGGKSAIGVGG- 1971
Query 2813 ENKTTVEDKTHVETISTEVGVRNAYLDAALALGAVKDAAEAVKQAKDQYSQAQR--DYA- 2869
+ T + T N AA + +A + Q Y++ + D A
Sbjct 1972 -DLTAQGARLDFGQGGTVAAKGNVTFGAASTTSTI-NANSSGDQGNRSYAETRHGSDQAL 2029
Query 2870 -----SGKITKEALDDSKANVAMATANLANAQ---IAVGSAAATAAA------SSATYGF 2915
G T + NV +T +L +A G A S T+
Sbjct 2030 TGTTVKGGDTLNVVSGKDINVIGSTIDLKKGDANLLAAGDVNVGAVTERHVYNSRETHSR 2089
Query 2916 TIGANGERIETTNTTNTTQGKWQGSTLELNNLTLKSENQDVNVQGSRLTATGTTSFDGTK 2975
+ +G +I ++ +T GS + + +++ S +D+NVQGS + T + +
Sbjct 2090 SGVVSGTKIASSQDATSTVAN--GSLISADGVSIGS-GKDINVQGSTVVGTHDVALNAAH 2146
Query 2976 DLNVTAGTEHSQQETSSKTNSQSVSYTYGGGGSASIGKQTSTSESKSLTYVNSEVTLNKT 3035
D+N+T + SQ T+ + Q GGG S S+G +++S + N+ T+
Sbjct 2147 DVNITTSQDTSQSSTTYQ--EQHSGLMSGGGLSFSVGNSKLAQQNQSSSVTNNASTVGSV 2204
Query 3036 EGRL-----NSLNIKGGEVSIQDRGNLQVNNIHVESLQDTASSSNSSRGGSIGGGYGSGS 3090
+G L N+L++KG ++ NI V+S DT + + G
Sbjct 2205 DGNLTVNAGNTLHVKGSDLVAGKDVTGTAANIVVDSATDTTRQAQQQQTSKSG------- 2257
Query 3091 KNITASYNQSKGSSDSAWVNTTSKLLIGNAQNDANLDAMGVKNITNIGGVIANANKNADG 3150
+T + S G + + ++ T + D+N A + +I G V A G
Sbjct 2258 --LTVGLSGSVGDAINNAISETQAAR--ESAKDSNGRASALHSIAAAGDV-------AFG 2306
Query 3151 SLTDHKNLNYTGNLELKDLQDHNNNNSSGFNVSTNIGIPQGGSKAASTAPKGSTTIGLNS 3210
L G L D S G VS S T +GS+ +N+
Sbjct 2307 GL---------GAKALLDGAKGPQAPSIGVQVSVGSSHSSMQSSEDQTIQRGSS---INA 2354
Query 3211 SGQETEQLT-KATLGQGSVTNATADTNRDINNTQEITRDQTTGMLNGSVTVDHRLLSESG 3269
G T T G++T A ++ N N I +Q L + D S S
Sbjct 2355 GGNAKLIATGNGTPKDGNITIAGSNVNAA--NVALIANNQVN--LVNTTDTDKTQSSNSS 2410
Query 3270 RAEIVKEQEQLIENFRQSAENLAKALPDGVYKDKALQTLNDVQAKLYNLPSEYKEVGVVG 3329
V + N + ++ +A DG D A+Q + A + V+G
Sbjct 2411 SGSSVGVS--IGTNGIGVSASMQRAHGDG-NSDAAIQNNTHINASQTATIVSGGDTNVIG 2467
Query 3330 NSVASELLKRGMESQDVEALFSKLDFFYAAKEFSEIQNQLTDLEKSGVNLETIFKQPK-- 3387
+V + + + A S D +A S T + G F
Sbjct 2468 ANVNANKVVADVGGNLNVA--SVQDTTVSAAHQSSAGGGFTISQTGG---GASFSAQNGH 2522
Query 3388 -----AGVNEQETIYAQGTDFETKVRSQTTLGMTILSNIADLGNSIKDISESTGVDIE 3440
AGVNEQ I A F+ V+ T L +++ AD + T DIE
Sbjct 2523 ADGNYAGVNEQAGIQAGSGGFDVTVKGNTDLKGAYIASTADASKNSLTTGTLTTSDIE 2580
Score = 73.2 bits (178), Expect = 9e-15
Identities = 241/1199 (20%), Positives = 443/1199 (37%), Gaps = 247/1199 (21%)
Query 220 TGQAVMNQGYLESFRVREGQITIQGKGLNGSLTPFTDVYARALQVNAGLYAKELNVVLGQ 279
T + + G+ E VR + GK + G T +Y ++L + ++K LN+ LG
Sbjct 1684 TTEKRLGDGFYEQQLVRNQVTQLTGKAVLGPYTDLQGMY-QSLMLAGAEWSKSLNLPLGM 1742
Query 280 N-DINVNDPTTSNVSPIQSNTSANNKPQFALDVGQLGGMYAGKIFLVGTEQGVGVRNAGS 338
+ T+NV +Q+ T + + ++L +Q
Sbjct 1743 SLSAQQVAALTTNVIIMQTETVGGQQ------------VLVPVVYLAKADQQ-------- 1782
Query 339 MNSTQSTLTLNANGDLTNTGNLIANQGQLQLNAENIKNTGNISSATSQVSLHSQNLDNSG 398
NANG L GN+ Q+ N+ +K A + ++L + +DN+
Sbjct 1783 ----------NANGPLITAGNIDLKNTQVFTNSGTVK-------ADTTLALQGKQIDNA- 1824
Query 399 LISSADELNIQQQGHVGNRGTLNAARIVVDAGSLANSGSIEQTGAQALDLKAGSMS-NIG 457
G L + + SL +G+++ T A ++KAGS+ N G
Sbjct 1825 ------------------FGALQSGGLT----SLDTTGNVDLTSA---NVKAGSLDLNAG 1859
Query 458 GKIGIAKTSSTGGNGSESGGGSQPVEPNNAAQDGGSLEVVNTDSTPTTPKTYETGYIHVR 517
K+ + + T + ++DG + +D T P
Sbjct 1860 NKLILDTATQT---------------THQVSRDGAT-----SDKTTLGPAA--------- 1890
Query 518 DQLNNDQGAIVAQGGIDLESNNGLDNQGGQLNLGRVKIQGERFNNDQGQLTVKQAEIQTN 577
LN A + GG D + N G N GG LN G +N Q + + N
Sbjct 1891 -NLNVAGDASIKTGG-DFQQNAGNLNVGGNLNAN----IGGNWNLGVQQTGEHKVVQRAN 1944
Query 578 SLSNQSGQLISNQKLNIQTQTANNQKGKIQSVD-QLDLNVANGLNNIEGQI---ASGQQL 633
+S+ + +N+ ++A G + + +LD G +G + A+
Sbjct 1945 GVSDTDLNSATGSTVNVGGKSAIGVGGDLTAQGARLDFG-QGGTVAAKGNVTFGAASTTS 2003
Query 634 NIQADQVNNQSGLIYSEQQ--------GIELKANHAINNTSG----IIQAKTQLNLASTQ 681
I A+ +Q Y+E + G +K +N SG +I + L
Sbjct 2004 TINANSSGDQGNRSYAETRHGSDQALTGTTVKGGDTLNVVSGKDINVIGSTIDLKKGDAN 2063
Query 682 LDNTSGHIQAENIQQQH---TTVNNTQGSIVAGQSLISTVDQFDN--HQGLIDAKNIQL- 735
L +G + + ++H + +++ +V+G + S+ D + LI A + +
Sbjct 2064 L-LAAGDVNVGAVTERHVYNSRETHSRSGVVSGTKIASSQDATSTVANGSLISADGVSIG 2122
Query 736 THQVLNNSGS-IYADQNIKITGQHILNTGSIAAGQNIQLNTAKLQHEQAALIAAGLDRQG 794
+ + +N GS + ++ + H +N I Q+ ++ Q + + L++ G
Sbjct 2123 SGKDINVQGSTVVGTHDVALNAAHDVN---ITTSQDTSQSSTTYQEQHSGLMSGG----- 2174
Query 795 KLTSTGDLDITAEQTTLHGQSFAGQQLKVASKQQIDATNGQLQAKNIDLASDAGDISTRA 854
G SF+ K+A + Q + AS G +
Sbjct 2175 ------------------GLSFSVGNSKLAQQNQSSSVTNN--------ASTVGSVDGNL 2208
Query 855 ATVIAEQLSLKSHDLIDNQQGTLSAQQLNLTANRLDNTQGHILHTGQDQLDLNFSQS--- 911
L +K DL+ + T +A + + + Q T + L + S S
Sbjct 2209 TVNAGNTLHVKGSDLVAGKDVTGTAANIVVDSATDTTRQAQQQQTSKSGLTVGLSGSVGD 2268
Query 912 -LNNQLGE---IRSNAAELNIKTALLNN--TEGQVVHAGTQQLNIQTAQLNGHLGHILSN 965
+NN + E R +A + N + + L++ G V G A L+G G +
Sbjct 2269 AINNAISETQAARESAKDSNGRASALHSIAAAGDVAFGGLG----AKALLDGAKGPQAPS 2324
Query 966 GTLQLKAGTLDVSGGVTSADQITIQANVLNNAQG--QLIQRGTSNPL--NLTIQQQ---- 1017
+Q+ G+ S + S++ TIQ NA G +LI G P N+TI
Sbjct 2325 IGVQVSVGSSHSS--MQSSEDQTIQRGSSINAGGNAKLIATGNGTPKDGNITIAGSNVNA 2382
Query 1018 ------LNNQAGLIQSATATDIKAGSLNNQRGTLSSAQGQNLDVDVAGKLDNSQSGQIYA 1071
NNQ L+ + T TD K S N+ G S+ G ++ + G + Q
Sbjct 2383 ANVALIANNQVNLV-NTTDTD-KTQSSNSSSG---SSVGVSIGTNGIGVSASMQRAHGDG 2437
Query 1072 GNQAHLQVGSIDNSHQGQINAQQNLQLTSQQQINNQSGQIVANGDVQIQSQGLNNSHGQM 1131
+ A +Q +N+H INA +Q+ IV+ GD + + N++ +
Sbjct 2438 NSDAAIQ----NNTH---INA-------------SQTATIVSGGDTNVIGANV-NANKVV 2476
Query 1132 GSLQGGLSLNTGSDTLINQSGLIQAKKDIGIQAQRIDNQQGQITTQGQAELISQAEIDNL 1191
+ G L++ + DT + S Q+ G + G A+ + A ++
Sbjct 2477 ADVGGNLNVASVQDTTV--SAAHQSSAGGGFTISQTGGGASFSAQNGHAD-GNYAGVNEQ 2533
Query 1192 EGAIAADLDVNIRSQGLNNNKGQISSAQGNLTLNAGNGTLTNQAATIVSGKTLTLSANQL 1251
G A ++ +G + KG ++ T +A +LT T TL+ + +
Sbjct 2534 AGIQAGSGGFDVTVKGNTDLKGAYIAS----TADASKNSLT----------TGTLTTSDI 2579
Query 1252 DNSNHGQINSQN---NADISIVKDINNTSGVIAAKQQLILSSQGLNNTTGQIGTVQGNLH 1308
+N +H NS A + + S V + + Q N++ Q T +
Sbjct 2580 ENHSHYSANSAGFSAGASVGVSTKAVGPSSVSGSGGVTPMVFQ--NDSGDQSATTKS--A 2635
Query 1309 IDAGSQLLNNQQGRIQSGQDLNLNATGIDNTQGQISSKNQLQLDSREQLLNNRQGTLSA 1367
+ AG+ + + Q +LN +AT N G +S +Q ++L+ + T++A
Sbjct 2636 VSAGAINITKPGEQTQDVANLNRDAT---NLNGTVSKTPDVQ-----KMLSQQADTMNA 2686
Score = 44.7 bits (104), Expect = 4e-06
Identities = 93/472 (20%), Positives = 168/472 (36%), Gaps = 50/472 (11%)
Query 2830 EVGVRNAYLDAALALGAVKDAAEAVKQAKDQYSQAQRDYA-SGKITKEALDDSKANVA-- 2886
E+G A L A G V D + ++ + ++ G +T ++ +V
Sbjct 167 EIGGAAAQLVIANQAGLVVDGGGFLNTSRATLTTGNPNFGPDGSLTGFNVNQGLISVVGA 226
Query 2887 -MATANLANAQIAVGSAAATAAASSATYGFTIGANGERIETTNTTN-TTQGKWQGSTLEL 2944
+ TAN+ + + A A + T G+N T N T G +++
Sbjct 227 GLDTANVDQVDLLARAVQINAKAYAKTLNVVAGSNQVDYNTLNATPIAANGPAPTIAIDV 286
Query 2945 NNL---------TLKSEN--------------QDVNVQGS-RLTATGTTSFDGTKDLNVT 2980
+ L + SEN D+ +Q + RL +G T+ G L+ +
Sbjct 287 SQLGGMYANRVFLVSSENGVGVANAGDIAAQAGDLTLQANGRLVLSGHTNAAGNMSLSAS 346
Query 2981 AGTEHS--QQETSSKTNSQSVSYTYGGGGSASIGKQTSTSESKSLTYVNSEVTLNKTEGR 3038
G ++S S T + T G +A + S + + + ++ T G
Sbjct 347 GGIQNSGVTYGKQSVTITTGADLTNSGALTAQQNLTANVGSLNSTGTLGAGINVDSTVGT 406
Query 3039 LNSLNIKGGEVSIQDRGNLQVNNIHVESLQDTASSSNSSRGGSIGGGYGSGSKNITASYN 3098
LN+ N N S+S ++ G++ +G N+ S
Sbjct 407 SGDLNVTSSGQLTATGTNSAAGNATFTGSGVNLSNSATAANGNLALTATAGDVNLAGSTV 466
Query 3099 QSKGSSDSAWVNTTSKLLIGNAQNDANLDAMGVKNITNIGGVIANANKNADGSLTDHKNL 3158
+KG+ +A + T GN + A + +G +++N GG N+ G L ++
Sbjct 467 SAKGAV-NAQASGTVVNDRGNLSSGAGM-TLGGGSLSNQGG-----RANSQGPL----SV 515
Query 3159 NYTGNLELKD--LQDHNNNNSSGFNVSTNIGIPQGGSK----AASTAPKGSTTIGLNSSG 3212
G + ++ L + + G + N G+ Q K AS I LN+ G
Sbjct 516 QMAGTVSNQNGMLSSQSTADVRGSAIQNNAGLIQSAGKQTIAGASIDNSAGRLISLNADG 575
Query 3213 QETEQLTKATLGQGSVTNATADTNRDINNTQEITRDQTTGMLNGSVTVDHRL 3264
T G+ N + D I ++T T +GS++ D L
Sbjct 576 LSVTATGALTNAAGA--NVSGDPGGVIGGKGDVTVQGNTVTNSGSMSADATL 625
Score = 42.7 bits (99), Expect = 1e-05
Identities = 134/618 (22%), Positives = 199/618 (32%), Gaps = 124/618 (20%)
Query 109 NGVTQVNIQTPSAGGVSRNTYSQ------------FDVGQEGAILNN----ARNNTQTQL 152
N VNI T S TY + F VG N NN T
Sbjct 2143 NAAHDVNITTSQDTSQSSTTYQEQHSGLMSGGGLSFSVGNSKLAQQNQSSSVTNNASTV- 2201
Query 153 GGWIQGNPWLAKGEAKVILNEVNSSNPSQLKGYIEVAGKQAQVVIANPSGLVCDGCGVIN 212
G + GN VN+ N +KG VAGK AN I
Sbjct 2202 -GSVDGNL------------TVNAGNTLHVKGSDLVAGKDVTGTAAN-----------IV 2237
Query 213 ADRFTLTTGQAVMNQ--------------GYLESFRVREGQITIQ-GKGLNGSLTPFTDV 257
D T TT QA Q G + + E Q + K NG + +
Sbjct 2238 VDSATDTTRQAQQQQTSKSGLTVGLSGSVGDAINNAISETQAARESAKDSNGRASALHSI 2297
Query 258 YARALQVNAGLYAKE-LNVVLGQN--DINVNDPTTSNVSPIQSNTSANNKPQFALDVGQL 314
A GL AK L+ G I V S+ S +QS+ + +++ G
Sbjct 2298 AAAGDVAFGGLGAKALLDGAKGPQAPSIGVQVSVGSSHSSMQSSEDQTIQRGSSINAG-- 2355
Query 315 GGMYAGKIFLVGTEQGV----GVRNAGS-MNSTQSTLTLNANGDLTNTGNLIANQGQLQL 369
G L+ T G + AGS +N+ L N +L NT + Q
Sbjct 2356 -----GNAKLIATGNGTPKDGNITIAGSNVNAANVALIANNQVNLVNTTDTDKTQSSNSS 2410
Query 370 NAENIK---NTGNISSATSQVSLHSQNLDNSGLISSADELNIQQQGHVGNRG-------T 419
+ ++ T I + S H ++ I + +N Q + + G
Sbjct 2411 SGSSVGVSIGTNGIGVSASMQRAHGDG-NSDAAIQNNTHINASQTATIVSGGDTNVIGAN 2469
Query 420 LNAARIVVDAGSLANSGSIEQTGAQALDLKAGSMSNIGGKIGIAKT----SSTGGNGSES 475
+NA ++V D G N S++ T + A S+ GG I++T S + NG
Sbjct 2470 VNANKVVADVGGNLNVASVQDT-----TVSAAHQSSAGGGFTISQTGGGASFSAQNGHAD 2524
Query 476 GGGSQPVEPNNAAQDGGSLEVV---NTD-------STPTTPKTYETGYIHVRDQLNNDQG 525
G + E G +V NTD ST K T + N
Sbjct 2525 GNYAGVNEQAGIQAGSGGFDVTVKGNTDLKGAYIASTADASKNSLTTGTLTTSDIENHSH 2584
Query 526 AIVAQGGIDLESNNGLDNQGGQLNLGRVKIQGERFNNDQGQLTVKQAEIQTNSLSNQSGQ 585
G ++ G+ + +G + G + N SG
Sbjct 2585 YSANSAGFSAGASVGVSTKA----VGPSSVSG-------------SGGVTPMVFQNDSGD 2627
Query 586 LISNQKLNIQTQTANNQKGKIQSVDQLDLNVANGLNNIEGQIAS----GQQLNIQADQVN 641
+ K + N K Q+ D +LN N+ G ++ + L+ QAD +N
Sbjct 2628 QSATTKSAVSAGAINITKPGEQTQDVANLN--RDATNLNGTVSKTPDVQKMLSQQADTMN 2685
Query 642 NQSGLIYSEQQGIELKAN 659
+ QGI L A+
Sbjct 2686 AAQAAGQTVSQGIGLYAD 2703
>D5CBA0 16S rRNA endonuclease CdiA [Enterobacter cloacae subsp.
cloacae (strain ATCC 13047 / DSM 30054 / NBRC 13535 / NCTC
10005 / WDCM 00083 / NCDC 279-56)]
Length=3321
Score = 387 bits (995), Expect = 5e-110
Identities = 737/3201 (23%), Positives = 1242/3201 (39%), Gaps = 616/3201 (19%)
Query 282 INVNDPTTSNVSPIQSNTSANNKPQFALD--VGQLGGMYAGKIFLVGTEQGVGVRNAGSM 339
+N+ P S +S + N K L+ GQL G + G G +
Sbjct 53 VNIATPNQSGISHNKYNDYNVGKEGLILNNATGQLNQTQLGGLIQNNPNLKAGQEAKGII 112
Query 340 NSTQSTLTLNANGDLTNTGN----LIANQGQLQLNAENIKNTGNISSATSQVSLHSQNLD 395
N N G G ++AN + N NT N++ T + L D
Sbjct 113 NEVTGANRSNLQGYTEVAGKAANVIVANPYGITCNGCGFINTPNVTLTTGKPVL-----D 167
Query 396 NSGLISSADELNIQQQGHVGNRGT-LNAARIVVDAGSLANSGSIEQTGAQALDLKAGSMS 454
SG + S D QG V G LN ++ DA S+ + + A DL+ + +
Sbjct 168 ASGKLQSLDVT----QGAVTIEGAGLNGSQS--DAVSIISRATEINVQLHAKDLRVVAGA 221
Query 455 NIGGKIGIAKTSSTGGNGSESGGGSQPVEPNNAAQDGGSLEVVNTDSTPTTPKTYETGYI 514
N + ++ G + G G+ P A D G+L + + ETG
Sbjct 222 N--------RVAADGSVSALKGEGTAP----KVAVDTGALGGMYANRIRLVSS--ETGVG 267
Query 515 HVRDQLNNDQGAIVAQGGIDLESNNGLDNQGGQLNLGRVKIQGERFNNDQGQLTVKQAEI 574
LN QG I + N L + ++ V ++G+ + G +TV
Sbjct 268 VNLGNLNARQGDIALSSAGKVVLKNTLASGSTTVSAADVTLRGD--HKAGGNVTVSGQ-- 323
Query 575 QTNSLSNQSGQLISNQKLNIQTQ-TANNQKGKIQSVDQLDLNVANGLNNIEGQIASGQQL 633
+L+ + ++ L + T+ T G + + L + +++ Q ++G+ L
Sbjct 324 --TALTLDQAHVAADNNLQLTTRGTLTQNGGAFTAANDATLAATTLIQSVDAQASAGRHL 381
Query 634 NIQADQVNNQSGLIYSEQQ----GIELKANHAINNTSGIIQAKTQLNLASTQLDNTSGHI 689
+ A++ +G + + QQ G EL ++ + + A+T L S N SG+I
Sbjct 382 AVNAEKNAALNGSVVAGQQLSVKGGELVQQGNLSASEIALNAQT-LTQESRSTTNASGNI 440
Query 690 QAENIQQQHTTVNNTQ--GSIVAGQSLISTVDQFDNHQGLIDAKNIQLTHQVLNNSGSIY 747
TT ++Q GS AGQSL + NH L + ++ + +N+G++
Sbjct 441 TL-------TTSGHSQLKGSTTAGQSLAVSAGSLANHGALAAVADTRINTGIFSNTGTVQ 493
Query 748 ADQNIKITGQHILNTGSI--AAGQNIQLNTAKLQHEQAALIAAGLDRQGKLTSTGDLDIT 805
+ ++ ++G I ++G++ A+ +I+ + A L E A + G L ++G L I+
Sbjct 494 GN-SLTVSGTDITSSGALKSASTLDIRADNATLSGETGAKGKTTVTASGNLNNSGTL-IS 551
Query 806 AEQTTLHGQSFAGQQLKVASKQQIDATNGQLQAKNIDLASDAGDISTRAATVIAEQLSLK 865
+ TL+ Q N S ++T T A S+
Sbjct 552 DDTLTLNAA----------------------QIVNSGTLSGVRGLTTSGKTFTASATSVT 589
Query 866 SHD---LIDNQQGTLSAQQLNLTANRLDNTQGHILHTGQDQLDLNFSQSLNNQLGEIRSN 922
D ++N TL+ + +A QG L+T +Q+ N +G N
Sbjct 590 QSDGDVALNNTDTTLAGET---SAGGAVTVQGRSLNTTAT------AQTQGNSVGVAVQN 640
Query 923 AAELNIKTALLNNTEGQVVHAGTQQLNIQTAQLNGHLGHILSNGTLQLKAGTLDVSGGVT 982
A EG G L ++ LN H G ++G L+++ G L SG +T
Sbjct 641 A-----------KLEGTQAAKGNMTLKADSS-LN-HTGKSSASG-LKVETGHLSNSGTLT 686
Query 983 SADQITIQANVLNNAQGQLIQRGTSNPLNLTIQQQLNNQAGLIQSATATDIKAGSLNNQR 1042
++ + V+N G LI G + L+L + N +G++ S +A + LNN
Sbjct 687 ASALVIDSPEVIN---GGLIHAGQT--LSLVTRLLDNRSSGVLYSPSALSLSLSELNNA- 740
Query 1043 GTLSSAQGQNLDVDVAGKLDNSQSGQIYAGNQAHLQVGSIDNSHQGQINAQQNLQLTSQQ 1102
G ++S +L L NS G++ +G + ++ NS +G + AQ ++T+Q
Sbjct 741 GIITSDAALSLS---GSNLTNS--GEL-SGTSLAIDYETLKNSAEGMLLAQGANRITAQS 794
Query 1103 QINNQSGQIVAN----GDVQIQSQGLNNSHGQMGSLQGGLSLNTGSDTLINQSGLIQAKK 1158
+ +G +V N +++S GL + G L+L TGS TL +
Sbjct 795 V--SSAGSMVGNTLTLNADRLESAGLLQGDSALSLTAGILNLLTGSRTLTGGA------- 845
Query 1159 DIGIQAQRIDNQQGQITTQGQAELISQAEIDNLEGAIAADLDVNIRSQGLNNNKGQISSA 1218
+G+ + GQ+ QGQ I + N G+ A +++ + G +N G++ S
Sbjct 846 -LGLSGTTLTTA-GQL--QGQDVSIRSHDWTN-RGSSLATGSLDVTTAGTLSNTGELMS- 899
Query 1219 QGNLTLNA----GNGTLTNQAATIVSGKTL----TLSANQLDNSNHGQINSQNNADIS-- 1268
QGN TLNA +G + + ++GKTL TL N++ NS I+
Sbjct 900 QGNGTLNAVTTVNSGNMLSAGDLSLNGKTLRNSGTLQGNRVTAHQDTITNSGTLTGIAAL 959
Query 1269 -----------IVKDINNTSGVIAAKQQLILSSQGLNNTTGQIGTVQGNLHIDAGSQLLN 1317
++ +N+ SG + +L ++ L N G QG + L N
Sbjct 960 MLAARLEMAAPLLTLVNDASGSLLTAGELSVTGGDLRNA----GQWQGKRVLIHAQALTN 1015
Query 1318 NQQGRIQSGQDLNLNATGIDNTQGQISSKNQLQLDSREQLLNNRQGTLSAENLTIDSGEL 1377
+ ++ D +++T +I+S +L L + L G A++LT+ + L
Sbjct 1016 GGAIQAENLLDAQIDSTLTGTAGSKITSNGELALSA---LTLANSGQWIAKHLTLGASTL 1072
Query 1378 NNDQGLIQAQQSIQIDTHQHNLSNTNSGAQGGILSQGNIQLN--NIQTLDNQQGYLASAQ 1435
NN G I ++ + L+ N+ A G +LS G + L+ N QG +
Sbjct 1073 NNS-GEITGVVALSVA-----LTQLNNQAGGKLLSAGALTLDVENATNAGQIQGKATT-- 1124
Query 1436 QLDLQANQVFNQNGTLLAAKQLNLQGTGQNQLLNNQSGQMLSMGGMNLNIDQINNKG--- 1492
+ A Q+ N A LN G L N SG +LS + ++ +NN+G
Sbjct 1125 ---VTAGQLINSGRLQGEALTLNASGA----LNNTASGVLLSENALTVSTATLNNQGTLQ 1177
Query 1493 -------KANT-ADADSHIMAAGELNITTQQLDNQNTLNTDPANTSIQGIDA----NTLN 1540
KA T D +++ G+L +T +L N ++ + + A N L
Sbjct 1178 GGGESSVKATTRVQNDGKMLSGGKLTLTAPELANSSSGLVQAVRLLLDVVKAVNGGNVLA 1237
Query 1541 VTSKVLN----NQSGVIRSSADQNLNVQQALNNQSGQISSEKQLTLVGDQLEINNLNGQI 1596
T L + SG ++ AD N Q N SG + LT+ GD L+ N +G++
Sbjct 1238 TTRAELRGSSLDNSGTLQG-ADLQANYQSVTN--SGTVLGTTSLTINGDALD-NTESGKL 1293
Query 1597 LAGTALDLIAQSLSGDGKLLSLGNAKLSLQNDYIHSSGAQLQANQDLSLSTKGNIINNGT 1656
+G L L ++ SG G ++SLG+ L L N +++ L A++ LS+S++ + N+G
Sbjct 1294 YSGDKLLLDVRNYSGRGDVVSLGDTTLKLVNALVNTG--TLAASKTLSVSSQNAMTNSGV 1351
Query 1657 INAGNQLALNAAN-ITNQQAGKIESHDTRLTAQNTLNNTG---LINGDFTRLQAETLNNQ 1712
+ GN +AL+A TN + + AQ+ L N GD E +
Sbjct 1352 MQ-GNAIALSAGGAFTNNGTLTTGNGSSTFNAQSLLLNASGSLQAGGDVQLTSRENITVN 1410
Query 1713 GTGRIYGTTLAIQANTLNNQPDSTGTAPVIASRGDLHLGVQTLNNLSNPTDYTSQALIFS 1772
G G+ A TL N +I + ++ L ++N+
Sbjct 1411 GFTGTAGSLTMTAAGTLLN-------TALIYAGNNISLFAARIHNIY------------- 1450
Query 1773 AGNLYLGAALDANDYATGQADV-IHNESATIESL-GDMNLSAKQINNINKYFKTEQVEVS 1830
G++ +L A G+A+ + N S TIE+ GD+ ++ + N Q E
Sbjct 1451 -GDILADNSLWMQKNAVGEANAEVVNRSGTIETTRGDITVNTGHLLNEADGLTVSQSERE 1509
Query 1831 RKDGLEKYCDAWCTFDGN-------------YYDGNPY---------------------- 1855
D + + + ++D N DG+
Sbjct 1510 YPDAIPAADEHYFSYDLNGRRSDFVLLLEDWKNDGSKVVYDWYEQCLGSGANGSGQCRDR 1569
Query 1856 -------EDWMRYYYSEITYETRTTESAPGQIKAGGHLDLNGAQVVNDKSQILAGGELKN 1908
ED ++ SE T S+ +I AG + +N + N S ILAG
Sbjct 1570 VDYRLTGEDIRQFLLSESVVSVSATGSS-ARIAAGRDITINAGTLDNRASHILAGRNAVL 1628
Query 1909 EGGTIDSGTQIAGIRKIVNTGTQVKY---WKY----EGQWD--NPFENSSETTFDLS--- 1956
GGT+++ + G R T Q +Y W Y + +W+ + + S FD
Sbjct 1629 AGGTLNNLSAEGGRRV---TYVQAEYRCEWFYRDCSDSKWEPLTQYPDGSWGWFDEDYGW 1685
Query 1957 ---ISQALGNQNLN-----QNQLSTVAVSNNQSAEHIQNSQTTQQEINGLQTSNNNTQLN 2008
+ LG + S ++ N SA + T N + SN
Sbjct 1686 YGWVPYILGERTTEFVADGGVYRSVISAGGNVSANFTSDISNTNVTANSGEFSNT----- 1740
Query 2009 QTKDVDLDQLNL-------KDSQSQNAPQASAVET---VQQQSATSAPSSTPQGTSEEIR 2058
+D LN K S++ Q + + Q + T A G+S +
Sbjct 1741 ----IDAPTLNTLSPEAIGKGLNSESLAQGGSADIRFPEQLGNITDALKDISGGSSLSDQ 1796
Query 2059 SIDFSNIKVP--NSALYKVNADSKAGYLI------------------------------- 2085
+ N +P N+ + + D + YLI
Sbjct 1797 NGSSGNYPLPSGNNGYFVPSTDPDSPYLITVNPKLDELGNMDDSLFNGLYDLLGITPGAT 1856
Query 2086 --ETDPAFADYKKWLSSDYMLDALGLDPALQQKRLGDGFYEQRLVQDQIANLTGYRFLEG 2143
ET+ A+ D ++L S Y LD LGL+P + LGD ++ R V + I N TG R++ G
Sbjct 1857 PRETNSAYTDRNQFLGSSYFLDRLGLNPDRDYRFLGDAAFDTRYVSNAILNQTGSRYING 1916
Query 2144 FANDDEQYKALMNNGITFAKLYGLRPGIALTAAQTAQLTSDIVWLVEQSVTLPDGTITKA 2203
+D +Q + LM++ K GL+ G+ALTA Q A L ++W +S T+ T+
Sbjct 1917 IGSDLDQMRYLMDSAAEQQKTLGLKFGVALTAEQVAALDKSMLWW--ESATINGQTV--- 1971
Query 2204 LVPQVYVKVRVGDLKGDGTLLSGNSVNLKLDGDLIN-GATIAGREALQITADNVQNLNGR 2262
++P+VY+ + + G+++SGN+V L G++IN G+TIA + L I + N
Sbjct 1972 MIPKVYLSPKDVTVHS-GSVISGNNVQLA-GGNVINSGSTIAAQNGLSIDSSN------- 2022
Query 2263 IQGNQVAIETQKDLNNIGGQIIAKDAMALKVGGNLNIESTTRTSESKVGNFSSSITNVDR 2322
L+N+ +A L GG LN+ + + N S+I+
Sbjct 2023 ------------SLSNL-------NAGLLSAGGGLNLSAL-----GDINNIGSTIS---- 2054
Query 2323 VAGLYVGNGSTKQLDPNQATLMLNVAGNSSLKGVQINNSNSATVLNT-TGNVDLGTVSVG 2381
G T L+ +VAG+ INN A N GNV VG
Sbjct 2055 --------GKTVGLE--------SVAGS-------INNITRAQQWNVDAGNVHFSGTDVG 2091
Query 2382 KQETLKIDDKNGYQLKQQQDVGSQIKSAGSLLINGQNITSKAVDLNSQQGDIQLSAQKDI 2441
K T I +G ++ QD+ + G N+ S G + ++A DI
Sbjct 2092 K--TASITATDGLTMRAGQDIN----------VTGANV--------SAGGSLGMAAGNDI 2131
Query 2442 VLDNGLNQSTVSSQSQSKGSFGGKKSSTYDASSSTSIANQLNAGQNIIINSAQG-NISAT 2500
N V+S+ ++ G+ +T + +S T + L+AG ++ + + N A
Sbjct 2132 ---NITANEIVTSEGRA-----GRNRATTETASVTHQGSTLSAGDDLTLQAGNDVNARAA 2183
Query 2501 HLQAEAGNNIQIHAQQGNVTLLSAIDDKRESSTSSKKGVATYNNRQSGYIDQEVAQTTLK 2560
+ AE IQ +V LL+ +R SS + KK + RQ G T +
Sbjct 2184 AIAAEGDVGIQAGR---DVDLLAEASMERSSSQAKKKTAIDESVRQQG--------TEIA 2232
Query 2561 AGDTVDINAAKNIELQANDVQAGNSIYVGNTLMQRQADGSLKAADGSLMPENVTLSTLAT 2620
+G I A +++ QA DV A G + A G +V L+T
Sbjct 2233 SGGNTVILAGRDVTAQAADVTA---------------QGDIGVAAG----RDVNLTTATE 2273
Query 2621 KDEQWDEQQKGYRGIVKDIVKATAVGLAGIEALAPGLKAPKITVSESTGKRTEQISQTGS 2680
D ++ EQ K G + K T+ E + R + GS
Sbjct 2274 SDYRYREQTKTSSGFLS--------------------KKTTHTIEEESATR-----EKGS 2308
Query 2681 SLKADNVYVGSSGQTTLTSTDITAKNTILL--GQKVTLNAAEEQKIT--VESTSKETVQG 2736
L DNV V + + + + + L G V + AA + T K + G
Sbjct 2309 LLSGDNVTVSAGNNLRVLGSAVAGDGDVALSAGNNVDIVAATNTDTAWRFKETKKSGLMG 2368
Query 2737 LGAKLNKDSIRLGGFVLEDASQSSKTTETTHKLGSINTENLKIQG--------------- 2781
G GF + SSK+T + G+ +E+ G
Sbjct 2369 TGGI---------GFTIG----SSKSTHDLREQGTTQSESFSTVGSTGGNVSIAAGKQAH 2415
Query 2782 VEGVDILGQ-NITATGDTLIDHGRGDLNVGGYENKTTVEDKTHVETISTEVGVRNAYLDA 2840
+ G DI+ Q +I+ TGD+++ D K T ++K ++ V + A A
Sbjct 2416 IGGADIIAQKDISLTGDSVVIEPGHD--------KRTRDEKFEQKSSGLTVALSGA---A 2464
Query 2841 ALALGAVKDAAEAVKQAKDQYSQAQRDYASGKITKEALDDSKANVAMATANLANAQIAVG 2900
A+ A++ KQ+ D A + T+ AL +A A+A +
Sbjct 2465 GSAVNNAVTTAQSAKQSSDSRLAALQG------TQAALSGVQAGQAVALDQVKGDSDKRN 2518
Query 2901 SAAATAAASSATYGFTIGANGERIETTNTTNTTQGKWQGSTLEL-NNLTLKSENQDVNVQ 2959
+ SA+ G + +E+ TT GSTL NN+T+K+ D+ V
Sbjct 2519 N---NTIGVSASIGSQSSKSSSHMESETTT--------GSTLSAGNNVTIKATGSDITVA 2567
Query 2960 GSRLTATGTTSFDGTKDLNVTAGTEHSQQETSSKTNSQSVSYTYG-----GGGSASIGKQ 3014
GS++ A + D +D+N+ A + Q+T+ K +S S G GG SI
Sbjct 2568 GSQIKAGKDVTLDAARDVNLIASQD--TQQTTGKNSSSGGSLGVGVGVGSGGAGISISAN 2625
Query 3015 TSTS----------ESKSLTYVNSEVTLNKTEGRLNSLNIKGGEVSIQDRGNLQVNNIHV 3064
++S ++++ + VT+N + GE + D G ++ +
Sbjct 2626 ANSSKGHEKGNGVWQNETTVDAGNRVTINTGRDATIAGAQVSGETVVADIGR----DLTI 2681
Query 3065 ESLQDTA--SSSNSSRGGSIGGGYGSGSKNITASYNQSKGSSDSAWVNTTSKLLIGNAQN 3122
S QD+ +S +S G G +G+G + + + ++ K +SD V S L GN
Sbjct 2682 ASTQDSDHYNSKQNSVSGGAGYTFGAGGFSGSINVSRDKMTSDYDSVQEQSGLFAGNGGF 2741
Query 3123 DANLDAMGVKNITNI-GGVIANANKNADGSLTDHKNLNYTGNLELKDLQDHNNNNSSGFN 3181
D V N T + GVIA+ + T KN TG L D+ +N + F
Sbjct 2742 DVT-----VGNHTQLDSGVIAS-------TATADKNRLDTGTLGFSDI-----HNQADFK 2784
Query 3182 VS-TNIGIPQGGSKAASTAPKGSTTI--GLNSSGQETEQLTKATLGQGSVTNATADTNRD 3238
GI GGS A + + G +SG E T+A + +G T D
Sbjct 2785 TEHQGAGISSGGSIGKQFAGNMANALLAGGGNSG-HAEGTTQAAVSEG--TLIIRDKENQ 2841
Query 3239 INNTQEITRDQTTGMLNGSVT 3259
+ +++RD NGS++
Sbjct 2842 KQDVADLSRDAEHA--NGSIS 2860
Score = 353 bits (906), Expect = 1e-99
Identities = 444/1709 (26%), Positives = 737/1709 (43%), Gaps = 212/1709 (12%)
Query 107 SSNGVTQVNIQTPSAGGVSRNTYSQFDVGQEGAILNNARNN-TQTQLGGWIQGNPWLAKG 165
++NGV VNI TP+ G+S N Y+ ++VG+EG ILNNA QTQLGG IQ NP L G
Sbjct 46 AANGVPVVNIATPNQSGISHNKYNDYNVGKEGLILNNATGQLNQTQLGGLIQNNPNLKAG 105
Query 166 -EAKVILNEVNSSNPSQLKGYIEVAGKQAQVVIANPSGLVCDGCGVINADRFTLTTGQAV 224
EAK I+NEV +N S L+GY EVAGK A V++ANP G+ C+GCG IN TLTTG+ V
Sbjct 106 QEAKGIINEVTGANRSNLQGYTEVAGKAANVIVANPYGITCNGCGFINTPNVTLTTGKPV 165
Query 225 MN-QGYLESFRVREGQITIQGKGLNGSLTPFTDVYARALQVNAGLYAKELNVVLGQNDIN 283
++ G L+S V +G +TI+G GLNGS + + +RA ++N L+AK+L VV G N +
Sbjct 166 LDASGKLQSLDVTQGAVTIEGAGLNGSQSDAVSIISRATEINVQLHAKDLRVVAGANRVA 225
Query 284 VNDPTTSNVSPIQSNTSANNKPQFALDVGQLGGMYAGKIFLVGTEQGVGVRNAGSMNSTQ 343
+ +VS ++ +A P+ A+D G LGGMYA +I LV +E GVGV N G++N+ Q
Sbjct 226 AD----GSVSALKGEGTA---PKVAVDTGALGGMYANRIRLVSSETGVGV-NLGNLNARQ 277
Query 344 STLTLNANGDLTNTGNLIANQGQLQLNAENIKNTGNISSATSQVSLHSQNLDNSGLISSA 403
+ L++ G + L + G ++A ++ G+ A V++ Q A
Sbjct 278 GDIALSSAGKVVLKNTLAS--GSTTVSAADVTLRGD-HKAGGNVTVSGQTALTLDQAHVA 334
Query 404 DELNIQQQGHVGNRGTL---NAARIVVDAGSLANSGSIEQTGAQALDLKAGSMSNIGGKI 460
+ N+Q + RGTL A + +LA + I+ AQA AG + +
Sbjct 335 ADNNLQ----LTTRGTLTQNGGAFTAANDATLAATTLIQSVDAQA---SAGRHLAVNAEK 387
Query 461 GIAKTSSTGGNGSESGGGSQPVEPNN--AAQDGGSLEVVNTDSTPTTPKT-----YETGY 513
A S S G + V+ N A++ + + + +S TT + +G+
Sbjct 388 NAALNGSVVAGQQLSVKGGELVQQGNLSASEIALNAQTLTQESRSTTNASGNITLTTSGH 447
Query 514 IHVRDQLNNDQGAIVAQGGI----------DLESNNGLDNQGGQLNLGRVKIQGERFNND 563
++ Q V+ G + D N G+ + G + + + G +
Sbjct 448 SQLKGSTTAGQSLAVSAGSLANHGALAAVADTRINTGIFSNTGTVQGNSLTVSGTDITSS 507
Query 564 QGQLTVKQAEIQTNSLSNQSGQLISNQKLNIQTQTANNQKGKIQSVDQLDLNVANGLNN- 622
+ +I+ ++ + SG+ + K + N G + S D L LN A +N+
Sbjct 508 GALKSASTLDIRADN-ATLSGETGAKGKTTVTASGNLNNSGTLISDDTLTLNAAQIVNSG 566
Query 623 ----IEGQIASGQQLNIQADQVNNQSGLIYSEQQGIELKANHAINNTSGIIQAKTQLNLA 678
+ G SG+ A V G + L A + +Q ++ A
Sbjct 567 TLSGVRGLTTSGKTFTASATSVTQSDGDVALNNTDTTL-AGETSAGGAVTVQGRSLNTTA 625
Query 679 STQLDNTSGHIQAENIQQQHTTVNNTQGSIVAGQSLISTVDQFDNHQGLIDAKNIQLTHQ 738
+ Q S + +N + + T ++ A SL NH G A +++
Sbjct 626 TAQTQGNSVGVAVQNAKLEGTQAAKGNMTLKADSSL--------NHTGKSSASGLKVETG 677
Query 739 VLNNSGSIYADQNIKITGQHILNTGSIAAGQNIQLNTAKLQHEQA---------ALIAAG 789
L+NSG++ A + I ++N G I AGQ + L T L + + +L +
Sbjct 678 HLSNSGTLTASA-LVIDSPEVINGGLIHAGQTLSLVTRLLDNRSSGVLYSPSALSLSLSE 736
Query 790 LDRQGKLTSTGDLDITAEQTTLHGQSFAGQQLKVASKQQIDATNGQLQAKNID-----LA 844
L+ G +TS L ++ T G+ +G L + + ++ G L A+ +
Sbjct 737 LNNAGIITSDAALSLSGSNLTNSGE-LSGTSLAIDYETLKNSAEGMLLAQGANRITAQSV 795
Query 845 SDAGDISTRAATVIAEQLSLKSHDLIDNQQG-TLSAQQLNLTANRLDNTQGHILHTGQDQ 903
S AG + T+ A++ L+S L+ +L+A LNL T G + G
Sbjct 796 SSAGSMVGNTLTLNADR--LESAGLLQGDSALSLTAGILNLLTGSRTLTGGAL---GLSG 850
Query 904 LDLNFSQSLNNQLGEIRSN----------AAELNIKTALLNNTEGQVVHAGTQQLNIQTA 953
L + L Q IRS+ L++ TA + G+++ G LN T
Sbjct 851 TTLTTAGQLQGQDVSIRSHDWTNRGSSLATGSLDVTTAGTLSNTGELMSQGNGTLNAVTT 910
Query 954 QLNGHLGHILSNGTLQLKAGTLDVSGGVTSADQITIQANVLNNAQGQLIQRGTSNPL-NL 1012
+ G++LS G L L TL SG T+Q N + Q + GT + L
Sbjct 911 V---NSGNMLSAGDLSLNGKTLRNSG--------TLQGNRVTAHQDTITNSGTLTGIAAL 959
Query 1013 TIQQQLNNQA---GLIQSATATDIKAGSLNNQRGTLSSA---QGQNLDVDVAGKLDNSQS 1066
+ +L A L+ A+ + + AG L+ G L +A QG+ + + A L N
Sbjct 960 MLAARLEMAAPLLTLVNDASGSLLTAGELSVTGGDLRNAGQWQGKRVLIH-AQALTN--G 1016
Query 1067 GQIYAGNQAHLQVGS-IDNSHQGQINAQQNLQLTSQQQINNQSGQIVANGDVQIQSQGLN 1125
G I A N Q+ S + + +I + L L++ N SGQ +A + + + LN
Sbjct 1017 GAIQAENLLDAQIDSTLTGTAGSKITSNGELALSALTLAN--SGQWIAK-HLTLGASTLN 1073
Query 1126 NSHGQMGSLQGGLSLNTGSDTLINQSG--LIQAKKDIGIQAQRIDNQQGQITTQGQAELI 1183
NS G + G ++L+ L NQ+G L+ A G ++N QG+A +
Sbjct 1074 NS----GEITGVVALSVALTQLNNQAGGKLLSA----GALTLDVENATNAGQIQGKATTV 1125
Query 1184 SQAEIDNLEGAIAADLDVNIRSQGLNNNKGQISSAQGNLTLNA----------GNGTLTN 1233
+ ++ N G + + S LNN + ++ LT++ G G +
Sbjct 1126 TAGQLIN-SGRLQGEALTLNASGALNNTASGVLLSENALTVSTATLNNQGTLQGGGESSV 1184
Query 1234 QAAT-------IVSGKTLTLSANQLDNSNHGQINSQNNADISIVKDINNTSGVIAAKQQL 1286
+A T ++SG LTL+A +L NS+ G + + + +VK +N G + A +
Sbjct 1185 KATTRVQNDGKMLSGGKLTLTAPELANSSSGLVQAVRLL-LDVVKAVN--GGNVLATTRA 1241
Query 1287 ILSSQGLNNTTGQIGTVQGNLHIDAGSQLLNNQQGRIQSGQDLNLNATGIDNTQ-GQISS 1345
L L+N+ GT+QG + A Q + N G + L +N +DNT+ G++ S
Sbjct 1242 ELRGSSLDNS----GTLQG-ADLQANYQSVTN-SGTVLGTTSLTINGDALDNTESGKLYS 1295
Query 1346 KNQLQLDSREQLLNNRQGTLSAENLTIDSGELNNDQGLIQAQQSIQIDTHQHNLSNTNSG 1405
++L LD R + R +S + T+ + G + A +++ + + + TNSG
Sbjct 1296 GDKLLLDVRN--YSGRGDVVSLGDTTLKLVNALVNTGTLAASKTLSVSSQN---AMTNSG 1350
Query 1406 AQGG---ILSQGNIQLNNIQTLDNQQGYLASAQQLDLQANQVFNQNGTLLAAKQLNLQGT 1462
G LS G NN TL G + FN LL A +LQ
Sbjct 1351 VMQGNAIALSAGGAFTNN-GTLTTGNG------------SSTFNAQSLLLNASG-SLQAG 1396
Query 1463 GQNQLLNNQSGQMLSMGGMNLNIDQINNKGKANTADADSHIMAAGELNITTQQLDNQNTL 1522
G QL + ++ + G ++ NTA I A +++ ++ N +
Sbjct 1397 GDVQLTSRENITVNGFTGTAGSLTMTAAGTLLNTA----LIYAGNNISLFAARIHN---I 1449
Query 1523 NTDPANTSIQGIDANTLNVTSKVLNNQSGVIRSS-ADQNLNVQQALNNQSGQISSEKQ-- 1579
D + + N + + + N+SG I ++ D +N LN G S+ +
Sbjct 1450 YGDILADNSLWMQKNAVGEANAEVVNRSGTIETTRGDITVNTGHLLNEADGLTVSQSERE 1509
Query 1580 ----LTLVGDQLEINNLNGQILAGTALDLIAQSLSGDGKLL------------SLGNAKL 1623
+ + +LNG+ + L+ + DG + + G+ +
Sbjct 1510 YPDAIPAADEHYFSYDLNGR---RSDFVLLLEDWKNDGSKVVYDWYEQCLGSGANGSGQC 1566
Query 1624 SLQNDYIHSSGAQLQ----ANQDLSLSTKGNIINNGTINAGNQLALNAANITNQQAGKIE 1679
+ DY +G ++ + +S+S G ++ I AG + +NA + N +A I
Sbjct 1567 RDRVDY-RLTGEDIRQFLLSESVVSVSATG---SSARIAAGRDITINAGTLDN-RASHIL 1621
Query 1680 SHDTRLTAQNTLNNTGLING-DFTRLQAE 1707
+ + A TLNN G T +QAE
Sbjct 1622 AGRNAVLAGGTLNNLSAEGGRRVTYVQAE 1650
Score = 176 bits (445), Expect = 7e-46
Identities = 326/1455 (22%), Positives = 565/1455 (39%), Gaps = 242/1455 (17%)
Query 82 LNTIADSQIIADKGAPTSQQPTILNSSNGVTQVNIQTPSAGGVSRNTY----SQFDVGQE 137
L +A + +A G+ ++ L +V + T + GG+ N S+ VG
Sbjct 215 LRVVAGANRVAADGSVSA-----LKGEGTAPKVAVDTGALGGMYANRIRLVSSETGVGVN 269
Query 138 GAILNNARNNTQTQLGGWIQGNPWLAKGEAKVILNEVNSSNPSQLKGYIEVAGK------ 191
LN + + G + LA G V +V + G + V+G+
Sbjct 270 LGNLNARQGDIALSSAGKVVLKNTLASGSTTVSAADVTLRGDHKAGGNVTVSGQTALTLD 329
Query 192 QAQVVIANPSGLVCDGCGVINADRFTLTTGQAVMNQGYLESFRVREG---QITIQGK--- 245
QA V N L G N FT + ++S + + + +
Sbjct 330 QAHVAADNNLQLTTRGTLTQNGGAFTAANDATLAATTLIQSVDAQASAGRHLAVNAEKNA 389
Query 246 GLNGSLTPFTDVYARALQVNAGLYAKELNVVLGQNDINVNDPT-----TSNVSP-IQSNT 299
LNGS+ V + L V G ++ N+ + +N T T+N S I T
Sbjct 390 ALNGSV-----VAGQQLSVKGGELVQQGNLSASEIALNAQTLTQESRSTTNASGNITLTT 444
Query 300 SANNKPQFALDVGQLGGMYAGKIFLVGTEQGVGVR--NAGSMNSTQSTL--TLNANG-DL 354
S +++ + + GQ + AG + G V N G ++T + +L +G D+
Sbjct 445 SGHSQLKGSTTAGQSLAVSAGSLANHGALAAVADTRINTGIFSNTGTVQGNSLTVSGTDI 504
Query 355 TNTGNLIANQGQLQLNAENIKNTGNISSATSQVSLHSQNLDNSGLISSADELNIQQQGHV 414
T++G L + L + A+N +G + S NL+NSG + S D L + +
Sbjct 505 TSSGAL-KSASTLDIRADNATLSGETGAKGKTTVTASGNLNNSGTLISDDTLTLNA-AQI 562
Query 415 GNRGTLNAARIVVDAGSL--ANSGSIEQT-GAQAL---DLKAGSMSNIGGKIGIAKTSST 468
N GTL+ R + +G A++ S+ Q+ G AL D ++ GG + + S
Sbjct 563 VNSGTLSGVRGLTTSGKTFTASATSVTQSDGDVALNNTDTTLAGETSAGGAVTVQGRSLN 622
Query 469 GGNGSESGGGSQPVEPNNAAQDG-----GSLEVVNTDSTPTTPKTYETGYIHVRDQLNND 523
+++ G S V NA +G G++ + S T K+ +G L+N
Sbjct 623 TTATAQTQGNSVGVAVQNAKLEGTQAAKGNMTLKADSSLNHTGKSSASGLKVETGHLSNS 682
Query 524 QGAIVAQGGIDLES--NNGLDNQGGQLNLGRVKIQGERFNNDQGQLTVKQAEIQTNSLSN 581
+ ID N GL + G L+L + N G L A + S N
Sbjct 683 GTLTASALVIDSPEVINGGLIHAGQTLSLVTRLLD----NRSSGVLYSPSALSLSLSELN 738
Query 582 QSGQLISNQKLNIQTQTANNQ---KGKIQSVDQLDLN-------VANGLNNIEGQIAS-- 629
+G + S+ L++ N G ++D L +A G N I Q S
Sbjct 739 NAGIITSDAALSLSGSNLTNSGELSGTSLAIDYETLKNSAEGMLLAQGANRITAQSVSSA 798
Query 630 ----GQQLNIQADQVNNQSGLIYSEQQGIELKANHAINNTSGIIQAKT--------QLNL 677
G L + AD++ + +GL L+ + A++ T+GI+ T L L
Sbjct 799 GSMVGNTLTLNADRLES-AGL---------LQGDSALSLTAGILNLLTGSRTLTGGALGL 848
Query 678 ASTQLDNTSGHIQAENIQQQHTTVNNTQGSIVAGQSLISTVDQFDNHQGLIDAKNIQLTH 737
+ T L T+G +Q +++ + N S+ G ++T N L+ N L
Sbjct 849 SGTTL-TTAGQLQGQDVSIRSHDWTNRGSSLATGSLDVTTAGTLSNTGELMSQGNGTLNA 907
Query 738 QVLNNSGSIYADQNIKITGQHILNTGS-----IAAGQNIQLNTAKLQHEQAALIAAGL-- 790
NSG++ + ++ + G+ + N+G+ + A Q+ N+ L A ++AA L
Sbjct 908 VTTVNSGNMLSAGDLSLNGKTLRNSGTLQGNRVTAHQDTITNSGTLTGIAALMLAARLEM 967
Query 791 ---------DRQGKLTSTGDLDITAEQTTLHGQSFAGQQLKVASKQQIDATNGQLQAKNI 841
D G L + G+L +T GQ Q +V Q G +QA+N+
Sbjct 968 AAPLLTLVNDASGSLLTAGELSVTGGDLRNAGQ---WQGKRVLIHAQALTNGGAIQAENL 1024
Query 842 DLASDAGDISTRAATVIAEQLSLKSHDLIDNQQGTLSAQQLNLTANRLDNTQGHILHTGQ 901
A ++ A + I L L G A+ L L A+ L+N+ G I TG
Sbjct 1025 LDAQIDSTLTGTAGSKITSNGELALSALTLANSGQWIAKHLTLGASTLNNS-GEI--TGV 1081
Query 902 DQLDLNFSQSLNNQLG-------------EIRSNAAELNIKTALLNNTEGQVVHAGTQQ- 947
L + +Q LNNQ G E +NA ++ K + T GQ++++G Q
Sbjct 1082 VALSVALTQ-LNNQAGGKLLSAGALTLDVENATNAGQIQGKATTV--TAGQLINSGRLQG 1138
Query 948 ----LNIQTAQLNGHLGHILSNGTLQLKAGTLDVSGGVTSADQITIQANVLNNAQGQLIQ 1003
LN A N G +LS L + TL+ G + + +++A G+++
Sbjct 1139 EALTLNASGALNNTASGVLLSENALTVSTATLNNQGTLQGGGESSVKATTRVQNDGKMLS 1198
Query 1004 RGTSNPLNLTIQQQLNNQAGLIQSA------------------TATDIKAGSLNNQRGTL 1045
G L LT + N+ +GL+Q+ T +++ SL+N GTL
Sbjct 1199 GGK---LTLTAPELANSSSGLVQAVRLLLDVVKAVNGGNVLATTRAELRGSSLDNS-GTL 1254
Query 1046 SSA--QGQNLDVDVAGK-------------LDNSQSGQIYAGNQAHLQVGSIDNS----- 1085
A Q V +G LDN++SG++Y+G++ L V +
Sbjct 1255 QGADLQANYQSVTNSGTVLGTTSLTINGDALDNTESGKLYSGDKLLLDVRNYSGRGDVVS 1314
Query 1086 -------------HQGQINAQQNLQLTSQQQINNQSGQIVANGDVQIQSQGLNNSHGQMG 1132
+ G + A + L ++SQ + N SG + N + + + G ++G +
Sbjct 1315 LGDTTLKLVNALVNTGTLAASKTLSVSSQNAMTN-SGVMQGNA-IALSAGGAFTNNGTLT 1372
Query 1133 SLQGGLSLNTGSDTLINQSGLIQAKKDIGIQAQRIDNQQGQITTQGQAELISQ------- 1185
+ G + N S L+N SG +QA D+ + ++ G T G + +
Sbjct 1373 TGNGSSTFNAQS-LLLNASGSLQAGGDVQLTSRENITVNGFTGTAGSLTMTAAGTLLNTA 1431
Query 1186 ------------AEIDNLEGAIAADLDVNIRSQGLN-------NNKGQISSAQGNLTLNA 1226
A I N+ G I AD + ++ + N G I + +G++T+N
Sbjct 1432 LIYAGNNISLFAARIHNIYGDILADNSLWMQKNAVGEANAEVVNRSGTIETTRGDITVNT 1491
Query 1227 GNGTLTNQAATIVSGKTLTLSANQLDNSNHG--------QINSQNNADISIVKDINNTSG 1278
G+ L N+A G T++ S + ++ +N + + + +++D N
Sbjct 1492 GH--LLNEA----DGLTVSQSEREYPDAIPAADEHYFSYDLNGRRSDFVLLLEDWKNDGS 1545
Query 1279 VIAAKQQLILSSQGLNNTTGQIGTVQGNLHIDAGSQLLNNQQ----------GRIQSGQD 1328
+ G N + V L + Q L ++ RI +G+D
Sbjct 1546 KVVYDWYEQCLGSGANGSGQCRDRVDYRLTGEDIRQFLLSESVVSVSATGSSARIAAGRD 1605
Query 1329 LNLNATGIDNTQGQI 1343
+ +NA +DN I
Sbjct 1606 ITINAGTLDNRASHI 1620
Score = 70.5 bits (171), Expect = 6e-14
Identities = 226/1054 (21%), Positives = 397/1054 (38%), Gaps = 197/1054 (19%)
Query 353 DLTNTGNLIANQGQLQLNAENIKNTGNISSATSQVSLHSQNLD---NSGLISSADELNIQ 409
D+T + + +QL N+ N+G+ +A + +S+ S N N+GL+S+ LN+
Sbjct 1982 DVTVHSGSVISGNNVQLAGGNVINSGSTIAAQNGLSIDSSNSLSNLNAGLLSAGGGLNLS 2041
Query 410 QQGHVGNRGTLNAARIVVDAGSLANSGSIEQ-TGAQALDLKAGSMSNIGGKIG-IAKTSS 467
G + N G+ + + V G + +GSI T AQ ++ AG++ G +G A ++
Sbjct 2042 ALGDINNIGSTISGKTV---GLESVAGSINNITRAQQWNVDAGNVHFSGTDVGKTASITA 2098
Query 468 TGGNGSESGGGSQPVEPNNAAQDGGSLEVVNTDSTPTTPKTYETGYIHVRDQLNNDQGAI 527
T G +G N +A GGSL + + T T + A
Sbjct 2099 TDGLTMRAGQDINVTGANVSA--GGSLGMAAGNDINITANEIVTSEGRAGRNRATTETAS 2156
Query 528 VAQGGIDLESNNGLDNQGGQLNLGRVKIQGERFNNDQGQLTVKQAEIQTNSLSNQSGQLI 587
V G L + + L Q G N+ + AE + + L+
Sbjct 2157 VTHQGSTLSAGDDLTLQAG--------------NDVNARAAAIAAEGDVGIQAGRDVDLL 2202
Query 588 SNQKLNIQTQTANNQKGKIQSVDQLDLNVANGLNNIEGQIASGQQLNIQADQVNNQSGLI 647
+ + + A + +SV Q +A+G N + I +G+ + QA V Q +
Sbjct 2203 AEASMERSSSQAKKKTAIDESVRQQGTEIASGGNTV---ILAGRDVTAQAADVTAQGDIG 2259
Query 648 YSEQQGIELKANHAINNTSGIIQAKTQLNLASTQLDNTSGHIQAENIQQQHTTVNNTQGS 707
+ + + L T + + Q +S L + H I+++ T +GS
Sbjct 2260 VAAGRDVNL-----TTATESDYRYREQTKTSSGFLSKKTTH----TIEEESAT--REKGS 2308
Query 708 IVAGQSLISTVDQFDNHQGLIDAKNIQLTHQVLNNSGSIYADQNIKITGQHILNTGSIA- 766
+++G ++ ++ A N+++ G + G +A
Sbjct 2309 LLSGDNV------------------------------TVSAGNNLRVLGSAVAGDGDVAL 2338
Query 767 -AGQNIQLNTA---------KLQHEQAALIAAGLD-RQGKLTSTGDLDITAEQTTLHGQS 815
AG N+ + A K + + G+ G ST DL EQ T +S
Sbjct 2339 SAGNNVDIVAATNTDTAWRFKETKKSGLMGTGGIGFTIGSSKSTHDL---REQGTTQSES 2395
Query 816 FA-----GQQLKVASKQQIDATNGQLQA-KNIDLASDA------GDISTR------AATV 857
F+ G + +A+ +Q + A K+I L D+ D TR ++
Sbjct 2396 FSTVGSTGGNVSIAAGKQAHIGGADIIAQKDISLTGDSVVIEPGHDKRTRDEKFEQKSSG 2455
Query 858 IAEQLSLKSHDLIDNQQGTLSA--QQLNLTANRLDNTQGHI--LHTGQ----DQLDLNFS 909
+ LS + ++N T + Q + L TQ + + GQ DQ+ +
Sbjct 2456 LTVALSGAAGSAVNNAVTTAQSAKQSSDSRLAALQGTQAALSGVQAGQAVALDQVKGDSD 2515
Query 910 QSLNNQLGEIRSNAAELNIKTALLNN--TEGQVVHAGTQQLNIQTAQLNGHLGHILSNGT 967
+ NN +G S ++ + ++ + + T G + AG N T + G I G+
Sbjct 2516 KRNNNTIGVSASIGSQSSKSSSHMESETTTGSTLSAG----NNVTIKATG--SDITVAGS 2569
Query 968 LQLKAG---TLDVSGGVT-SADQITIQANVLNNAQGQLIQRGT---SNPLNLTIQQQLNN 1020
Q+KAG TLD + V A Q T Q N++ G + G S ++I N+
Sbjct 2570 -QIKAGKDVTLDAARDVNLIASQDTQQTTGKNSSSGGSLGVGVGVGSGGAGISISANANS 2628
Query 1021 QA------GLIQSATATDI-KAGSLNNQR-GTLSSAQ--GQNLDVDVAGKLD--NSQSGQ 1068
G+ Q+ T D ++N R T++ AQ G+ + D+ L ++Q
Sbjct 2629 SKGHEKGNGVWQNETTVDAGNRVTINTGRDATIAGAQVSGETVVADIGRDLTIASTQDSD 2688
Query 1069 IYAGNQAHLQVGS----IDNSHQGQINAQQNLQLTSQQQINNQSGQIVANGDVQIQSQGL 1124
Y Q + G+ G IN ++ + + QSG N
Sbjct 2689 HYNSKQNSVSGGAGYTFGAGGFSGSINVSRDKMTSDYDSVQEQSGLFAGN---------- 2738
Query 1125 NNSHGQMGSLQGGLSLNTGSDTLINQSGLIQAKKDIGIQAQRIDNQQGQITTQGQAELIS 1184
GG + G+ T ++ SG+I + D + T G +++ +
Sbjct 2739 -----------GGFDVTVGNHTQLD-SGVIAS-------TATADKNRLDTGTLGFSDIHN 2779
Query 1185 QAEIDNLEGAIAADLDVNIRSQGLNNNKGQISSAQGNLTLNAGNGTLTNQAATIVSGKTL 1244
QA+ +I Q N + + G N+G+ T QAA VS TL
Sbjct 2780 QADFKTEHQGAGISSGGSIGKQFAGNMANALLAGGG----NSGHAEGTTQAA--VSEGTL 2833
Query 1245 TLSANQLDNSNHGQINSQNNADISIVKDINNTSGVIA-----AKQQLILSSQGLNNTTG- 1298
+ D N Q+ AD+S +D + +G I+ K+Q L L G
Sbjct 2834 IIR----DKEN----QKQDVADLS--RDAEHANGSISPIFDKEKEQQRLQEVQLIGEIGS 2883
Query 1299 ---QIGTVQGNLH-IDAGSQLLNNQQGRIQSGQD 1328
I QG ++ ++AG + L + +G + G D
Sbjct 2884 QVVDIANTQGEINGLNAGRKELAD-KGITEPGAD 2916
Score = 59.7 bits (143), Expect = 1e-10
Identities = 230/1112 (21%), Positives = 407/1112 (37%), Gaps = 179/1112 (16%)
Query 2440 DIVLDNGLNQSTVSSQSQSKGSFGGKKSSTYDASSSTSIANQLNAGQ-NIIINSAQGNIS 2498
+ V D G+ +S +S+ +F S+T ++S +N ++A N + A G
Sbjct 1699 EFVADGGVYRSVISAGGNVSANFTSDISNTNVTANSGEFSNTIDAPTLNTLSPEAIGKGL 1758
Query 2499 ATHLQAEAGN-NIQIHAQQGNVTLLSAIDD-KRESSTSSKKGVATYNNRQSGYIDQEVAQ 2556
+ A+ G+ +I+ Q GN+T A+ D SS S + G + SG V
Sbjct 1759 NSESLAQGGSADIRFPEQLGNIT--DALKDISGGSSLSDQNGSSGNYPLPSGNNGYFVPS 1816
Query 2557 TTLKAGDTVDINAAKNIELQANDVQAGNSIYVGNTLMQRQADGSLKAADGSLMPENVTLS 2616
T + + +N K EL D N +Y L+ + + + + N L
Sbjct 1817 TDPDSPYLITVNP-KLDELGNMDDSLFNGLY---DLLGITPGATPRETNSAYTDRNQFLG 1872
Query 2617 TLATKDEQWDEQQKGYRGIVKDIVKATAVGLAGIEALAPGLKAPKITVSESTGKRTEQIS 2676
+ D + YR + V A + G +Q+
Sbjct 1873 SSYFLDRLGLNPDRDYRFLGDAAFDTRYVSNAILNQTGS-------RYINGIGSDLDQMR 1925
Query 2677 QTGSSLKADNVYVGSSGQTTLTSTDITAKN-TILLGQKVTLNAAEEQKITVESTSKETVQ 2735
S +G LT+ + A + ++L + T+N V + K+
Sbjct 1926 YLMDSAAEQQKTLGLKFGVALTAEQVAALDKSMLWWESATINGQTVMIPKVYLSPKDVTV 1985
Query 2736 GLGAKLNKDSIRL-GGFVLED----ASQSSKTTETTHKLGSINTENLKIQGVEGVDILGQ 2790
G+ ++ ++++L GG V+ A+Q+ + ++++ L ++N L G G
Sbjct 1986 HSGSVISGNNVQLAGGNVINSGSTIAAQNGLSIDSSNSLSNLNAGLLSAGG-------GL 2038
Query 2791 NITATGDTLIDHGRGDLNVGGYENKTTVEDKTHVETISTEVGVRNAYLDAALALGAVKDA 2850
N++A GD N+G +T+ KT VG+ + G++ +
Sbjct 2039 NLSALGDIN--------NIG-----STISGKT--------VGLESV-------AGSINNI 2070
Query 2851 AEAVKQAKDQYSQAQRDYASGKITKEALDDSKANVAMATANLANAQIAVGSAAATAAAS- 2909
A + D + GK D A N+ A ++ G + AA +
Sbjct 2071 TRAQQWNVDAGNVHFSGTDVGKTASITATDGLTMRAGQDINVTGANVSAGGSLGMAAGND 2130
Query 2910 -SATYGFTIGANGERIETTNTTNTTQGKWQGSTLEL-NNLTLKSENQDVNVQGSRLTATG 2967
+ T + + G TT T QGSTL ++LTL++ N DVN + + + A G
Sbjct 2131 INITANEIVTSEGRAGRNRATTETASVTHQGSTLSAGDDLTLQAGN-DVNARAAAIAAEG 2189
Query 2968 TTSFDGTKDLNVTAGTEHSQQETSSKTNSQSVSYTYGGGGSASIGKQTSTSESKSLTYVN 3027
+D+++ A E S + +SS+ K+T+ ES V
Sbjct 2190 DVGIQAGRDVDLLA--EASMERSSSQAK-----------------KKTAIDES-----VR 2225
Query 3028 SEVTLNKTEGRLNSLNIKGGEVSIQDRGNLQVNNIHVESLQD----TASSSNSSRGGSIG 3083
+ T + G N++ + G +V+ Q +I V + +D TA+ S+
Sbjct 2226 QQGTEIASGG--NTVILAGRDVTAQAADVTAQGDIGVAAGRDVNLTTATESDYRYREQTK 2283
Query 3084 GGYGSGSKNITASYNQSKGSSDSAWVNTTSKLLIGNAQNDANLDAMGVKNITNIGGVIAN 3143
G SK T + + + + LL G+ N+ N+ +G +A
Sbjct 2284 TSSGFLSKKTTHTIEEESATREKG------SLLSGD-----NVTVSAGNNLRVLGSAVAG 2332
Query 3144 ANKNADGSLTDHKNLNYTGNLELKDLQDHNNNNSSGFNVSTNIGIPQGGSKAASTAPKGS 3203
+ D +L+ N++ SG + IG G SK+ +
Sbjct 2333 ---DGDVALSAGNNVDIVAATNTDTAWRFKETKKSGLMGTGGIGFTIGSSKSTHDLREQG 2389
Query 3204 TTIGLNSS--GQETEQLTKATLGQGSVTNATADTNRDINNTQEI----------TRDQTT 3251
TT + S G ++ A Q + A +DI+ T + TRD+
Sbjct 2390 TTQSESFSTVGSTGGNVSIAAGKQAHIGGADIIAQKDISLTGDSVVIEPGHDKRTRDEKF 2449
Query 3252 GMLNGSVTVDHRLLSESGRAEIVKEQEQLIENFRQSAENLAKALPDGVYKDKALQTLNDV 3311
+ +TV L +G A + N +A++ ++ D L L
Sbjct 2450 EQKSSGLTV--ALSGAAGSA---------VNNAVTTAQSAKQS------SDSRLAALQGT 2492
Query 3312 QAKLYNLPSEYKEVGVVGNSVASELLKRGMESQDVEALFSKLDFFYAAKEFSEIQNQLTD 3371
QA L + + V + V + KR + V A ++K S ++++ T
Sbjct 2493 QAALSGVQAGQ---AVALDQVKGDSDKRNNNTIGVSASIGS----QSSKSSSHMESETT- 2544
Query 3372 LEKSGVNLETIFKQPKAGVNEQETIYAQGTDFETKVRSQTTLGMTILSNIADLGNSI--K 3429
+G L AG N TI A G+D T SQ G + + A N I +
Sbjct 2545 ---TGSTLS-------AGNNV--TIKATGSDI-TVAGSQIKAGKDVTLDAARDVNLIASQ 2591
Query 3430 DISESTGVDIEKVQLAVGLLISGPVRLVIESGKSMAVDSVVGEKVAQGVDILANSMTAAA 3489
D ++TG + SG S+ V VG A G+ I AN+ ++
Sbjct 2592 DTQQTTGKNSS-------------------SGGSLGVGVGVGSGGA-GISISANANSSKG 2631
Query 3490 HDTSVNTINNWTNPDKISELENSTGENKDASL 3521
H+ N T D + + +TG +DA++
Sbjct 2632 HEKGNGVWQNETTVDAGNRVTINTG--RDATI 2661
Score = 49.7 bits (117), Expect = 1e-07
Identities = 238/1280 (19%), Positives = 460/1280 (36%), Gaps = 156/1280 (12%)
Query 85 IADSQIIADKGAPTSQQPTILNSSNGVTQVNIQTPSAGGVSR-----------NTYSQFD 133
+A +I +Q ++SSN ++ +N SAGG +T S
Sbjct 1998 LAGGNVINSGSTIAAQNGLSIDSSNSLSNLNAGLLSAGGGLNLSALGDINNIGSTISGKT 2057
Query 134 VGQEGAILNNARNNTQTQLGGWIQGNPWLAKGEAKVILNEVNSSNPSQLKGYIEVAGKQA 193
VG E ++ + N T+ Q GN + + +++ + G AG+
Sbjct 2058 VGLE-SVAGSINNITRAQQWNVDAGNVHFSGTDVG------KTASITATDGLTMRAGQDI 2110
Query 194 QVVIANPS-----GLVCDGCGVINADRFTLTTGQAVMNQGYLESFRVREGQITIQGKGLN 248
V AN S G+ I A+ + G+A N+ E+ V T+ G +
Sbjct 2111 NVTGANVSAGGSLGMAAGNDINITANEIVTSEGRAGRNRATTETASVTHQGSTLSA-GDD 2169
Query 249 GSLTPFTDVYARALQVNAGLYAKELNVVLGQNDINVNDPTTSNVSPIQSNTSANNKPQFA 308
+L DV ARA + A ++ + G+ D+++ + S +S++ A K
Sbjct 2170 LTLQAGNDVNARAAAIAA---EGDVGIQAGR-DVDL----LAEASMERSSSQAKKK---- 2217
Query 309 LDVGQLGGMYAGKIFLVGTEQGVGVRNAGSMNSTQSTLTLNANGDLTNTGNLIANQGQLQ 368
T VR G+ ++ + A D+T + QG +
Sbjct 2218 ------------------TAIDESVRQQGTEIASGGNTVILAGRDVTAQAADVTAQGDIG 2259
Query 369 LNAENIKNTGNISSAT-SQVSLHSQNLDNSGLISSADELNIQQQGHVGNRGT-LNAARIV 426
+ A N+++AT S Q +SG +S I+++ +G+ L+ +
Sbjct 2260 VAA---GRDVNLTTATESDYRYREQTKTSSGFLSKKTTHTIEEESATREKGSLLSGDNVT 2316
Query 427 VDAG--------SLANSGSIEQTGAQALDLKAGSMSNIGGKIGIAKTSSTGGNGSESGGG 478
V AG ++A G + + +D+ A + ++ + K S G +GG
Sbjct 2317 VSAGNNLRVLGSAVAGDGDVALSAGNNVDIVAATNTDTAWRFKETKKSGLMG----TGGI 2372
Query 479 SQPVEPNNAAQDGGSLEVVNTDSTPTTPKTYETGYIHVRDQLNNDQGAIVAQGGIDLESN 538
+ + + D ++S T T I Q + I+AQ I L +
Sbjct 2373 GFTIGSSKSTHDLREQGTTQSESFSTVGSTGGNVSIAAGKQAHIGGADIIAQKDISLTGD 2432
Query 539 NGLDNQGGQLNLGRVKIQGERFNNDQGQLTVKQAEIQTNSLSN-----QSGQLISNQKL- 592
+ + G + + E+F LTV + ++++N QS + S+ +L
Sbjct 2433 SVVIEPGHD-----KRTRDEKFEQKSSGLTVALSGAAGSAVNNAVTTAQSAKQSSDSRLA 2487
Query 593 ---NIQTQTANNQKGKIQSVDQLDLNVANGLNNIEGQIAS-GQQLNIQADQVNNQ--SGL 646
Q + Q G+ ++DQ+ + NN G AS G Q + + + ++ +G
Sbjct 2488 ALQGTQAALSGVQAGQAVALDQVKGDSDKRNNNTIGVSASIGSQSSKSSSHMESETTTGS 2547
Query 647 IYSEQQGIELKANHAINNTSGI-IQAKTQLNLASTQLDNTSGHIQAENIQQQHTTVNNTQ 705
S + +KA + +G I+A + L + + N I +++ QQ +++
Sbjct 2548 TLSAGNNVTIKATGSDITVAGSQIKAGKDVTLDAARDVNL---IASQDTQQTTGKNSSSG 2604
Query 706 GSIVAGQSLISTVDQFDNHQGLIDAKNIQLTHQVLNNSGSIYADQNIKI-TGQHILNTGS 764
GS+ G + S +K + + V N ++ A + I TG+ G+
Sbjct 2605 GSLGVGVGVGSGGAGISISANANSSKGHEKGNGVWQNETTVDAGNRVTINTGRDATIAGA 2664
Query 765 IAAGQNI------QLNTAKLQ------HEQAALIAAGLDRQGKLTSTGDLDITAEQTTLH 812
+G+ + L A Q +Q ++ G +G ++++ ++ T
Sbjct 2665 QVSGETVVADIGRDLTIASTQDSDHYNSKQNSVSGGAGYTFGAGGFSGSINVSRDKMTSD 2724
Query 813 GQSFAGQQLKVASKQQIDATNG---QLQAKNIDLASDAG----DISTRAATVIAEQLSLK 865
S Q A D T G QL + I + A D T + I Q K
Sbjct 2725 YDSVQEQSGLFAGNGGFDVTVGNHTQLDSGVIASTATADKNRLDTGTLGFSDIHNQADFK 2784
Query 866 S--HDLIDNQQGTLSAQQLNLTANRLDNTQGHILHT-GQDQLDLNFSQSLNNQLGEIRSN 922
+ + G++ Q AN L G+ H G Q ++ + + +
Sbjct 2785 TEHQGAGISSGGSIGKQFAGNMANALLAGGGNSGHAEGTTQAAVSEGTLIIRDKENQKQD 2844
Query 923 AAELNIKTALLNNTEGQVVHAGTQQLNIQTAQLNGHLG-HILSNGTLQ-----LKAGTLD 976
A+L+ N + + +Q +Q QL G +G ++ Q L AG +
Sbjct 2845 VADLSRDAEHANGSISPIFDKEKEQQRLQEVQLIGEIGSQVVDIANTQGEINGLNAGRKE 2904
Query 977 VSG------GVTSADQI-TIQANVLNNAQG---QLIQRGTSNPLNLTIQQQLNNQAGLIQ 1026
++ G ++D++ N L + GT + L Q+ + +Q
Sbjct 2905 LADKGITEPGADASDEVKAAYQNALRETDAYKTTTAKYGTGSDL----QRGIQAATAALQ 2960
Query 1027 SATATDIKAGSLNNQRGTLSSAQGQNLDVD---VAGKLDNSQSGQIYAGNQAHLQVGSID 1083
+D+ A L+ G + +D A + ++ G A Q +
Sbjct 2961 GLAGSDLTAALAGASAPELAYRIGHGMGIDNNTAAKTIAHAILGGAVAALQGNSAAAGAA 3020
Query 1084 NSHQGQINAQ----------QNLQLTSQQQINNQSGQIVANGDVQIQSQGLNNSHGQMGS 1133
+ G++ A+ ++L S++Q S + + G + G
Sbjct 3021 GAATGELAAKAIAGMLYPDVKDLSTLSEEQKQTVSALATISAGMAGGLAGDSTGSAVAGG 3080
Query 1134 LQGGLSLNTGSDTLINQSGLIQA--KKDIGIQAQRIDNQQGQITTQGQA--ELISQAEID 1189
G + S L+ + + A + + Q I + G G A ++ + D
Sbjct 3081 QAGKNAAENNSLALVARGCAVAAPCRTKVAEQLLEIGAKAGIAGLAGAAVKDMADKMTSD 3140
Query 1190 NLEGAIAADL----DVNIRSQGLNNNKGQISSAQGNLTLNAGNGTLTNQAATIVSGKTLT 1245
LE + ++ ++ + L ++K S GNL G N ++ +G T
Sbjct 3141 ELEHLVTLEMMGNDEIIAKYVSLLHDKYAPSHTGGNLLPETLPGHTGNNTGSVDTGPNHT 3200
Query 1246 LSANQLDNSNHGQINSQNNA 1265
+ N+ ++S + A
Sbjct 3201 GNTNRQNDSGSNNTGNTEGA 3220
>A0A1S4NYE3 tRNA nuclease CdiA [Escherichia coli (strain STEC_O31)]
Length=3253
Score = 379 bits (974), Expect = 1e-107
Identities = 747/3223 (23%), Positives = 1244/3223 (39%), Gaps = 572/3223 (18%)
Query 662 INNTSGIIQAKTQLNLASTQLDNTSGHIQAENIQQQHTTVNNTQGSIVAGQSLISTVDQF 721
I ++SG + K L +T + T + +N + +V T G +
Sbjct 280 ILSSSGKLVLKNSLAGGNTTVTGTDVSLSGDNKAGGNLSVTGTTGLTL------------ 327
Query 722 DNHQGLIDAKNIQLTH--QVLNNSGSIYADQNIKITGQHILNT-GSIAAGQNIQLNTA-- 776
N L+ KN+ L+ Q++ N G + A QN ++ QH+ T G++ A +N+ L T
Sbjct 328 -NQSRLVTDKNLVLSSSGQIVQNGGELTAGQNAMLSAQHLNQTSGAVNAAENVTLTTTGG 386
Query 777 -KLQHEQAA---------------LIAAGLD---RQGKLTSTG-----DLDITAEQTTLH 812
L+ A + AG D + G ++TG L +TA T
Sbjct 387 ITLKGRSVAGKTLTVSSGSLNNGGTLGAGRDATVKTGTFSNTGAVQGNGLKVTATDLTST 446
Query 813 GQSFAGQQLKVASKQQIDATNGQLQAKNIDLASDAGDISTRAATVIAEQLSLKSHDLIDN 872
G +G L ++++ +G AK+ + +G + R V + L+L + + N
Sbjct 447 GSIKSGSTLDISARNA--TLSGDAGAKDSARVTVSGTLENRGRLVSDDVLTLSATQI--N 502
Query 873 QQGTLS-AQQLNLTANRLDNTQGHILHTGQDQLDLNFSQSLNNQLGEIRSNAAELNIKTA 931
GTLS A++L +A+ L T+ + ++ L LN S ++ L S +++K
Sbjct 503 NSGTLSGAKELVASADTLTTTEKSVTNS-DGNLMLN---SASSTLAGETSAGGTVSVKGN 558
Query 932 LLNNTEGQVVHAGTQQLNIQTAQLNGHLGHILSNGTLQLKAGTLDVSGGVTSADQITIQA 991
L T + +++Q AQL+G + L L A G +SA +++ A
Sbjct 559 SLKTTTTAQTQGNSVSVDVQNAQLDGTQA---ARDILTLNASEKLTHSGKSSAPSLSLSA 615
Query 992 NVLNNAQGQLIQRGTSNPLNLTIQQQLNNQAGLIQSATATDIKAGSLNNQR-GTLSSAQG 1050
L ++ G L+ L Q Q +GL+Q + + L+NQ+ GTL SA
Sbjct 616 PELTSS-GVLVASA------LNTQSQTLTNSGLLQGEASLTVNTQRLDNQQNGTLYSAAD 668
Query 1051 QNLDVDVAGKLDNSQSGQIYAGNQAHLQVGSIDNSHQGQINAQQ-NLQLTSQQQINNQSG 1109
LD+ D SG I N L S+ N G+I A N++ T+
Sbjct 669 LTLDIP-----DIRNSGLITGDNGLTLNTASLSNP--GKITADTLNVRATT--------- 712
Query 1110 QIVANGDVQIQSQGLNNSHGQMGSLQGGLSLNTGSDTLINQS-GLIQAKKDIGIQAQRID 1168
+GD G LQG +L DTL S G D+ ++ + +
Sbjct 713 ---LDGD---------------GLLQGAAALALAGDTLSQGSHGRWLTAGDLSLRGKTL- 753
Query 1169 NQQGQITTQGQAELISQAEIDNLEGAIAADLDVNIRSQGLNNNKGQISSAQGNLTLNAGN 1228
N G TTQGQ L QA+ G++ A ++ + G + G I S QG+ TLNA
Sbjct 754 NTAG--TTQGQ-NLTVQADRWANSGSVLATGNLTASATGQLTSTGDIMS-QGDTTLNAAT 809
Query 1229 GTLTNQAATIVSGKTLTLSANQLDNS-----NHGQINSQNNADISIVKDINN-------- 1275
T+ +++S TL+L N LDNS NH ++ ++ + V ++
Sbjct 810 ---TDNRGSLLSAGTLSLDGNSLDNSGTVQGNHVTLHHRSTDNSGTVTGLSGLTLHSADG 866
Query 1276 --TSGVIAAKQQLILSSQGLNNTTGQIGTVQG-NLHIDAGSQLLNNQQGRIQSGQDLNLN 1332
SG + ++ L+LS+ + N+ G +QG N+ +DA S G +QS DL L
Sbjct 867 LTNSGALLSQNSLVLSAGDVTNS----GRIQGQNITLDASSL---TSSGAVQSALDLALT 919
Query 1333 ATG--IDNTQGQISSKNQLQLDSREQLLNNRQGTLSAENLTIDSGELNNDQGLIQAQQSI 1390
+G I T +I++ +L + +L N QG +SA+ L ++ L+N G I S+
Sbjct 920 LSGDVIAATGSKITALGDARLTGK--VLGN-QGLISAKTLEVNGDSLSNS-GEISGVNSL 975
Query 1391 QIDTHQHNLSNTNSGAQGGILSQGNIQLNNIQTLDNQQGYLASAQQLDLQANQVFNQNGT 1450
+ T NL GG L+ ++N L + ++ + + +V ++G
Sbjct 976 NV-TLSGNLQQHGKMLTGGALNVNARDISNSGQLQGADNRITASSLAN--SGRVQGESGL 1032
Query 1451 LLAAKQLNLQGTGQNQLLNNQSGQMLSMGGMNLNIDQINNKGK-----------ANTADA 1499
L T N L N SG +LS L+ + N G A A
Sbjct 1033 TL---------TLLNALTNQTSGVLLSQNVSALSAPVLTNDGTIQGNGKTTLSAATQAHN 1083
Query 1500 DSHIMAAGELNITTQQLDNQNTLNTDPANTSIQGID-------ANTLNVTSKVLNNQSGV 1552
I++ GEL TT L ++ + AN +T L N+
Sbjct 1084 SGKILSGGELTFTTPDYSGSGWLQATDLLLNVAKLAGNGTVMAANQATLTGNSLTNRG-- 1141
Query 1553 IRSSADQNLNVQQALNNQSGQISSEKQLTLVGDQLEINNLNGQILAGTALDLIAQ--SLS 1610
+ +A N+N Q N SG + + LT+ G+ L NN G++ +G D++A+ SLS
Sbjct 1142 LFQAAQLNVNTQTITN--SGTLLGNQGLTIKGNNL--NNAGGKVFSGG--DMLAEMVSLS 1195
Query 1611 GDGKLLSLGNAKLSLQNDYIHSSGAQLQANQDLSLSTKGNIINNGTINAGNQLALNAANI 1670
G G+L++LGN L L ++ + AN+ LS+S++G+I N T+ GN + LNAA
Sbjct 1196 GAGQLVALGNLTLKLTRGL--TAQGVIAANKQLSVSSQGDITNGATLQ-GNGITLNAAG- 1251
Query 1671 TNQQAGKIESHDTRLTAQNTLNNTGLINGDFTRLQAETLNNQGTGRIYGTTLAIQANTLN 1730
RLT NN L G+ GT + G+ +A+ A
Sbjct 1252 -------------RLT-----NNGQLTAGN------------GTTALSGSGIAMNA---- 1277
Query 1731 NQPDSTGTAPVIASRGDLHLGVQTLNN----LSNPTDYTSQALIFSAGNLYLGAA----- 1781
+ G + SRGD+ L T L+ + AL+++ NL L A+
Sbjct 1278 SGSLQAGGDVSLTSRGDITLDAFTGTTGSLMLTAAGAVINTALLYAGNNLSLFASTIRNH 1337
Query 1782 ---LDANDYATGQADV-------IHNESATIESL-GDMNL-------SAKQINNINKYFK 1823
+ A D Q DV + N S IE+ GD+ + + IN Y
Sbjct 1338 HGDMLAGDSLVMQKDVSGAANAEVINTSGNIETTRGDITIRTGHLLNQREGINETKSYIP 1397
Query 1824 TEQVEVS-------------RKDGLEKYCDAWCTFDGNYYDGNPYEDWMRYYYSEITYET 1870
E V V +DG Y +W G +D +T T
Sbjct 1398 VENVAVPDGANSVSVRVGDLGEDGWGYYVKSWSGTAGGGFDAWAVPTEKGATRKFLTGTT 1457
Query 1871 RTTESAPG---QIKAGGHLDLNGAQVVNDKSQILAGGELKNEGGTIDSGTQIAGIRKIVN 1927
R A G +I AG +L ++ ++ N S +LA G + SG+Q+
Sbjct 1458 RVDVGATGGDARISAGNNLLIDADKLDNTGSHLLASGFVSL------SGSQLNNQSFFGY 1511
Query 1928 TGTQVKYWKYEGQWD----------NPFENSSETTFDLSISQALGNQNLNQNQLSTVAVS 1977
T + ++Y G+ TF LS + ++ Q + +
Sbjct 1512 TQDEYNVYRYYGKLAMIPNDGHLQYGDASADDRVTFTLSGAPEYVTRDTGQALRAVIQAG 1571
Query 1978 NNQSA---EHIQNSQTTQQE---INGLQTSNNNTQLNQTKDVDLDQLNLKDSQSQNAPQA 2031
N +A I N+ TT N L NT + N+ +Q AP
Sbjct 1572 KNVTAVFSSDISNTSTTSNAGRITNTLAAPEINTPAEK---------NISPRMAQLAPDG 1622
Query 2032 SAVETVQQQSATSAPSSTPQGTSEEIRS-IDFSNIKVP--NSALYKVNADSKAGYLI--- 2085
+ + TV T + G+ ++ S I N +P N+ + +AD + YLI
Sbjct 1623 TEMLTVTAPDWTDTITRLTIGSGTDLASGIVEGNYPLPSGNNGYFVPSADPDSPYLITVN 1682
Query 2086 ------------------------------ETDPAFADYKKWLSSDYMLDALGLDPALQQ 2115
ETDPA+ D K++ S Y LD LGL P
Sbjct 1683 PKLDGLGKVDSSLFAGLYDLLRMHPGQAPRETDPAYTDEKQFPGSSYFLDRLGLKPEKDY 1742
Query 2116 KRLGDGFYEQRLVQDQIANLTGYRFLEGFANDDEQYKALMNNGITFAKLYGLRPGIALTA 2175
+ LGD ++ R V + + N G R++ G +D +Q + LM+N K GL+ G+ALTA
Sbjct 1743 RFLGDAAFDTRYVSNYMLNQIGGRYINGVGSDTDQMRYLMDNAARAQKALGLKFGVALTA 1802
Query 2176 AQTAQLTSDIVWLVEQSVTLPDGTITKALVPQVYVKVRVGDLKGDGTLLSGNSVNLKLDG 2235
Q A L I+W ++VT+ T+ +VP+VY+ + L+ +G+++SG +V+L
Sbjct 1803 DQVAALDQSILWY--KAVTIKGQTV---MVPEVYLSPKDVTLQ-NGSIISGQNVHLAGGN 1856
Query 2236 DLINGATIAGREALQI-TADNVQNLNGRI--QGNQVAIETQKDLNNIGGQIIAKDAMALK 2292
+G+T+ + L I +AD++ NL + G + ++ D+NNI I K
Sbjct 1857 VTNSGSTLMAQNNLTIDSADSLGNLESGLINAGGALGLKAMGDINNISATITGKTVRLES 1916
Query 2293 VGGNLNIESTTRTSESKVGNFSSSITNVDRVAGLYVGNGSTKQLDPNQATLMLNVAGNSS 2352
+ GN+N + TR S ++ S+ G + LD + N S
Sbjct 1917 LAGNVN--NLTRYSHWQLDAPEDSLALKHTYTGSIASVSAMDSLD-------IRADKNIS 1967
Query 2353 LKGVQINNSNSATVLNTTGNVDLGTVSVGKQETLKIDDKNGYQLKQQQDVGSQIKSAGSL 2412
+ G +I+ + A ++ GN DL ++ + + + + +Q +SAG
Sbjct 1968 VTGAEISAGDRAALI--AGN-DLSLNAIDRVSSRRHANSESHQ-----------RSAGLT 2013
Query 2413 LINGQN--ITSKAVDLNSQQGDIQLSAQKDIVLDNGLNQSTVSSQSQSKGSFGGKKSSTY 2470
I + + S D++SQ I +A+ +I + G + + ++ +S + S KK +
Sbjct 2014 TITAGDSVMLSAGRDVSSQGAGI--AAEDNITVRAGRDVNLLAEESVTGSSSYSKKKTVI 2071
Query 2471 DASSSTSIANQLNAGQNIIINSAQGNISATHLQAEAGNNIQIHAQQGNVTLLSAIDDKRE 2530
D + A + G I +A +I+A A NI ++A + +V L +A +
Sbjct 2072 DETVRQQGAEIASGGDTTI--TAGRDITAVASSVTATGNISVNAGR-DVALTTATESDYH 2128
Query 2531 SSTSSKKGVATYNNRQSGYIDQEVAQT---TLKAGDTVDINAAKNIELQANDVQAGNSIY 2587
+ KK + + + I + A L +G+ V +NA N+ +Q +DV A
Sbjct 2129 YLETKKKSGGFLSKKTTHTISENSATREAGALLSGNRVTVNAGDNLTVQGSDVVA----- 2183
Query 2588 VGNTLMQRQADGSLKAADGSLMPENVTLSTLATKDEQWDEQQKGYRGIVKDIVKATAVGL 2647
D SL A + +V + + D W K+ K+ GL
Sbjct 2184 --------DRDVSLAAGN------HVDVLAATSTDTSWR---------FKETKKS---GL 2217
Query 2648 AGIEALAPGLKAPKITVSESTGKRTEQISQTGSSLKADNVYVGSSGQTTLTSTDITAKNT 2707
G + + + K T T+ S + A NV + + Q ++ +D+ A
Sbjct 2218 MGTGGIGFTIGSSKTTHDRREAGTTQSQSASTIGSTAGNVSITAGKQAHISGSDVIANRD 2277
Query 2708 I-LLGQKVTLNAAEEQKITVESTSKETVQGLGAKLNKDSIRLGGFVLEDASQSSKTTETT 2766
I + G V ++ +++ TV+ ++ GL L S +G + + + +T E++
Sbjct 2278 ISITGDSVVVDPGHDRR-TVDEKFEQKKSGLTVAL---SGTVGSAINNAVTSAQETKESS 2333
Query 2767 -HKLGSINTENLKIQGVEGVDILGQNITATGDTLIDHGRGDLNVGGYENKTTVEDKTHVE 2825
+L ++ + GV+ TATGD N G T + K+ +
Sbjct 2334 DSRLKALQATKTALSGVQAGQAAAM-ATATGDP---------NATGVSLSLTTQ-KSKSQ 2382
Query 2826 TISTEVGVRNAYLDAALALGAVKDAAEAVKQAKDQYSQAQRDYASGKITKEALDDSKANV 2885
S V + L+A L V D + A G + +A +D
Sbjct 2383 QHSESDTVSGSTLNAGNNLSVVATGKNRGDNRGDIVIAGSQLKAGGNTSLDAAND----- 2437
Query 2886 AMATANLANAQIAVGSAAATAAASSATYGFTIGA-NGERIETTNTTNTTQGKWQGSTLEL 2944
+ + AN Q G ++S G +IGA G I + N +G +G+ E
Sbjct 2438 -ILLSGAANTQKTTG----RNSSSGGGVGVSIGAGKGAGISVFASVNAAKGSEKGNGTEW 2492
Query 2945 NNLTLKSENQDVNVQGSRLTATGTTSFDGTKDLNVTAGTEH-----SQQETSSKTNSQSV 2999
T S + V + R T +G + + A H SQQ+TS + Q+
Sbjct 2493 TETTTDS-GKTVTINSGRDTVLNGAQVNGNR---IIADVGHDLLISSQQDTSKYDSKQT- 2547
Query 3000 SYTYGGGGSASIGKQT-------STSESKSLTYVNSEVT--------LNKTEGRLNSL-- 3042
+ GGS + G T S + KS +E T + T GR L
Sbjct 2548 --SVAAGGSFTFGSMTGSGYIAASRDKMKSRFDSVAEQTGMFAGDGGFDITVGRHTQLDG 2605
Query 3043 ----NIKGGEVSIQDRGNLQVNNIHVESLQDTASSSNS-SRGGSIG-------------- 3083
+ + + D G L +++H E+ + S S S GGS G
Sbjct 2606 AVIASTATPDKNHLDTGTLGFSDLHNEADYKVSHSGISLSGGGSFGDKFQGNMPGGMISA 2665
Query 3084 GGYGSGSKNITAS----------------YNQSKGSSDSAWVNTTSKLLIGNAQNDANLD 3127
GG+ ++ T + N + S D A N + + + L
Sbjct 2666 GGHSGHAEGTTQAAVAEGTITIRDRDNQKQNPADLSRDPAHANDSISPIFDKEKEQRRLQ 2725
Query 3128 AMGVKNITNIGGVIAN------------ANKNADG-----SLTDHKNLNYTGNL----EL 3166
+G+ I++IG +A+ A K A G + T+ + Y L E
Sbjct 2726 TVGL--ISDIGSQVADIARTQGELNALKAAKEATGETLPANATEKQRQEYLAKLRDTPEY 2783
Query 3167 KDLQDHNNNNSS---GFNVSTNI--GIPQG---GSKAASTAPKGSTTIGLNSSGQETEQL 3218
K Q+ S G +T G+ G G+ A ++AP+ + + +
Sbjct 2784 KKEQEKYGTGSEIQLGIQAATAALQGLAGGNLAGALAGASAPELAHLLKSTEKDPAVNAI 2843
Query 3219 TKATLGQGSVTNATADTNRDINNTQEITRDQTTGMLNGSVTVDHRLLSESGRAEIVKEQE 3278
A LG G+V NN TG L + + L ++++ +EQ+
Sbjct 2844 AHAILG-GAVAAMQG------NNVAAGAAGAATGEL-AARAIAGMLYPGVKQSDLSEEQK 2895
Query 3279 QLIENFRQSAENLAKALPDGVYKDKAL--QTLNDVQAKLYNLPSEYKEVGVVGNSVASEL 3336
Q I + LA L A+ Q+ + Y SE E+ +A +
Sbjct 2896 QTISTLATVSAGLAGGLTGNSSASAAVGAQSGKNAVDNNYLSVSEKTEL-----EIAKQT 2950
Query 3337 LKRGMESQDVEALFSKLDFFYAAKEFSEIQNQLTDLEKSGVNLETIFKQPKAGVNEQETI 3396
LK + E K D S+ ++ +G + + V +
Sbjct 2951 LKNSKNPAEREKAQQKYDALLEKDIASD--KEVIAACGNGNAGSSACASARLKVIASKEG 3008
Query 3397 YAQGTDFETKVRSQTTLGMTILSNIADLGNSIKDISESTGVDIEKVQLAVGLLISGPVRL 3456
Y G + +K Q AD I ++ + T VD++ Q ++S +
Sbjct 3009 YEDG-PYNSKYSQQ----------YADAYGQIVNLLDITSVDVQNQQQVKDAMVSYFM-- 3055
Query 3457 VIESGKSMAVDSVVGE---KVAQGVDILANSMTAAAHDTSVNTINNWTNPDKISELENST 3513
++ VD + + QG++I A SMT N I DK ++ +
Sbjct 3056 -----ATLGVDQKTAQGYVETTQGLEIAAASMTPLFGQAVANKITALV--DKANKYPSGI 3108
Query 3514 GENKDASLKFANEVQKDKQGAEYLINAASGIIVGGIAKGTVKNNNSDIDISKSGFEIGNI 3573
G + A Q D + I+ A V K V N I + +G +
Sbjct 3109 GFKINQPEHLA---QLDGYSQKKGISGAHNADV--FNKAVVDNGVKIISETPTG-----V 3158
Query 3574 NPITGHKILGTHKDESNNTVGNYIVEGTKPSTK---DKVIKTD 3613
IT + KD + NT GNY G KP K D I TD
Sbjct 3159 RGITQVQYEIPTKDAAGNTTGNYKGNGAKPFEKTIYDPKIFTD 3201
Score = 360 bits (924), Expect = 9e-102
Identities = 446/1707 (26%), Positives = 734/1707 (43%), Gaps = 231/1707 (14%)
Query 107 SSNGVTQVNIQTPSAGGVSRNTYSQFDVGQEGAILNNARNNTQ-TQLGGWIQGNPWL-AK 164
++NGV VNI TP+ G+S N ++ ++VG+EG ILNNA TQLGG IQ NP L A
Sbjct 45 AANGVPVVNIATPNGAGISHNRFTDYNVGKEGLILNNATGKLNPTQLGGLIQNNPNLKAG 104
Query 165 GEAKVILNEVNSSNPSQLKGYIEVAGKQAQVVIANPSGLVCDGCGVINADRFTLTTGQAV 224
GEAK I+NEV N S L+GY EVAGK A V++ANP G+ CDGCG IN R TLTTG+ V
Sbjct 105 GEAKGIINEVTGGNRSLLQGYTEVAGKAANVMVANPYGITCDGCGFINTPRATLTTGRPV 164
Query 225 MN-QGYLESFRVREGQITIQGKGLNGSLTPFTDVYARALQVNAGLYAKELNVVLGQNDIN 283
MN G L++ V EG ITI G GL+G+ + + ARA +VNA L+AK+L V G N +
Sbjct 165 MNADGSLQALEVTEGSITINGAGLDGTRSDAVSIIARATEVNAALHAKDLTVTAGANRVT 224
Query 284 VNDPTTSNVSPIQSNTSANNKPQFALDVGQLGGMYAGKIFLVGTEQGVGVRNAGSMNSTQ 343
+ VS ++ + P+ A+D G LGGMYA +I L TE GVGV N G++ + +
Sbjct 225 AD----GRVSALKGE---GDVPKVAVDTGALGGMYARRIHLTSTESGVGV-NLGNLYARE 276
Query 344 STLTLNANGDLT-----NTGNLIANQGQLQLNAENIKNTGNIS-SATSQVSLHSQNL--D 395
+ L+++G L GN + L+ +N K GN+S + T+ ++L+ L D
Sbjct 277 GDIILSSSGKLVLKNSLAGGNTTVTGTDVSLSGDN-KAGGNLSVTGTTGLTLNQSRLVTD 335
Query 396 NSGLISSADELNIQQQGHV--GNRGTLNAARIVVDAGSLANSGSIEQTGAQALDLKAGSM 453
+ ++SS+ ++ +Q G + G L+A + +G++ + ++ T + LK S
Sbjct 336 KNLVLSSSGQI-VQNGGELTAGQNAMLSAQHLNQTSGAVNAAENVTLTTTGGITLKGRS- 393
Query 454 SNIGGKIGIAKTSSTGGNGSESGGGSQPVE----PNNAAQDGGSLEVVNTDSTPTTPKTY 509
+ GK + S G+ G V+ N A G L+V TD T T
Sbjct 394 --VAGKTLTVSSGSLNNGGTLGAGRDATVKTGTFSNTGAVQGNGLKVTATDLTST----- 446
Query 510 ETGYIHVRDQLNNDQGAIVAQGGIDLESNNG-LDNQGGQLNLGRVKIQGERFNNDQGQLT 568
G+I + +D+ + N L G + RV + G N +G+L
Sbjct 447 ---------------GSIKSGSTLDISARNATLSGDAGAKDSARVTVSGTLEN--RGRLV 489
Query 569 VKQAEIQTNSLSNQSGQLISNQKLNIQTQT-ANNQKGKIQSVDQLDLNVANGLNNIEGQI 627
+ + N SG L ++L T +K S L LN A+ + + G+
Sbjct 490 SDDVLTLSATQINNSGTLSGAKELVASADTLTTTEKSVTNSDGNLMLNSAS--STLAGET 547
Query 628 ASGQQLNIQADQVNNQSGLIYSEQQGIELKANHAINNTSGIIQAKTQLNLASTQLDNTSG 687
++G ++++ + + + ++ QG + + G A+ L L +++ SG
Sbjct 548 SAGGTVSVKGNSLKTTT---TAQTQGNSVSVDVQNAQLDGTQAARDILTLNASEKLTHSG 604
Query 688 HIQAENIQQQHTTVNNTQGSIVAGQSLISTVDQFDNHQGLIDAK-NIQLTHQVLNN--SG 744
A ++ + ++ G +VA S ++T Q + GL+ + ++ + Q L+N +G
Sbjct 605 KSSAPSLSLSAPELTSS-GVLVA--SALNTQSQTLTNSGLLQGEASLTVNTQRLDNQQNG 661
Query 745 SIYADQNIKITGQHILNTGSIAAGQNIQLNTAKLQHEQAALIAAGLDRQGKLTSTGDLDI 804
++Y+ ++ + I N+G I + LNTA L + GK+T+ +
Sbjct 662 TLYSAADLTLDIPDIRNSGLITGDNGLTLNTASLSN------------PGKITAD---TL 706
Query 805 TAEQTTLHGQSFAGQQLKVASKQQIDATNGQLQ-AKNIDLASDAGDISTRAATVIAEQLS 863
TTL G +G LQ A + LA D + + A LS
Sbjct 707 NVRATTLDG-------------------DGLLQGAAALALAGDTLSQGSHGRWLTAGDLS 747
Query 864 LKSHDLIDNQQGTLSAQQLNLTANRLDNTQGHILHTGQDQLDLNFSQSLNNQL---GEIR 920
L+ L N GT Q L + A+R N+ G +L TG N + S QL G+I
Sbjct 748 LRGKTL--NTAGTTQGQNLTVQADRWANS-GSVLATG------NLTASATGQLTSTGDIM 798
Query 921 SNAAELNIKTALLNNTEGQVVHAGTQQLNIQTAQLNGHL--GHILSNGTLQLKAGTLDVS 978
S + + A +N G ++ AGT L+ + +G + H+ + +GT+
Sbjct 799 SQ-GDTTLNAATTDN-RGSLLSAGTLSLDGNSLDNSGTVQGNHVTLHHRSTDNSGTVTGL 856
Query 979 GGVT--SADQIT-----IQANVLNNAQGQLIQRGTSNPLNLTIQQQLNNQAGLIQSATAT 1031
G+T SAD +T + N L + G + G N+T+ +G +QSA
Sbjct 857 SGLTLHSADGLTNSGALLSQNSLVLSAGDVTNSGRIQGQNITLDASSLTSSGAVQSALDL 916
Query 1032 DIK-AGSLNNQRGTLSSAQGQNLDVDVAGKLDNSQSGQIYAGNQAHLQVGSIDNSHQGQI 1090
+ +G + G+ +A G D + GK+ +Q G I A L+V S+ G+I
Sbjct 917 ALTLSGDVIAATGSKITALG---DARLTGKVLGNQ-GLISAKT---LEVNGDSLSNSGEI 969
Query 1091 NAQQNLQLTSQQQINNQSGQIVANGDVQIQSQGLNNSHGQMGSLQGGLSLNTGSDTLINQ 1150
+ +L +T + Q G+++ G + + ++ ++NS G LQG + T S +
Sbjct 970 SGVNSLNVTLSGNL-QQHGKMLTGGALNVNARDISNS----GQLQGADNRITASS--LAN 1022
Query 1151 SGLIQAKKDIGIQ-AQRIDNQQGQITTQGQAELISQAEIDNLEGAIAADLDVNIRSQGLN 1209
SG +Q + + + + NQ + +S + N +G I + + +
Sbjct 1023 SGRVQGESGLTLTLLNALTNQTSGVLLSQNVSALSAPVLTN-DGTIQGNGKTTLSAATQA 1081
Query 1210 NNKGQISSAQGNLTLN----AGNG------TLTNQA-----ATIVSGKTLTLSANQLDNS 1254
+N G+I S G LT +G+G L N A T+++ TL+ N L N
Sbjct 1082 HNSGKILSG-GELTFTTPDYSGSGWLQATDLLLNVAKLAGNGTVMAANQATLTGNSLTNR 1140
Query 1255 NHGQINSQNNADISIVKDINNTSGVIAAKQQLILSSQGLNNTTGQI-------------- 1300
Q A +++ SG + Q L + LNN G++
Sbjct 1141 GLFQA-----AQLNVNTQTITNSGTLLGNQGLTIKGNNLNNAGGKVFSGGDMLAEMVSLS 1195
Query 1301 GTVQ----GNLHIDAGSQLLNNQQGRIQSGQDLNLNATGIDNTQGQISSKNQLQLDSREQ 1356
G Q GNL + L QG I + + L++++ G D T G N + L++ +
Sbjct 1196 GAGQLVALGNLTLKLTRGL--TAQGVIAANKQLSVSSQG-DITNGATLQGNGITLNAAGR 1252
Query 1357 LLNNRQGTLSAENLTI---DSGELNNDQGLIQAQQSIQIDTHQHNLSNTNSGAQGGI-LS 1412
L NN G L+A N T SG N G +QA + + + + +G G + L+
Sbjct 1253 LTNN--GQLTAGNGTTALSGSGIAMNASGSLQAGGDVSLTSRGDITLDAFTGTTGSLMLT 1310
Query 1413 QGNIQLNNIQTLDNQQGYLASAQQLDLQANQVFNQNGTLLAAKQLNLQGTGQNQLLNNQS 1472
+N L + L L A+ + N +G +LA L +Q + S
Sbjct 1311 AAGAVINT--------ALLYAGNNLSLFASTIRNHHGDMLAGDSLVMQ--------KDVS 1354
Query 1473 GQMLSMGGMNLNIDQINNKGKANTADAD-----SHIMAAGE-LNITTQQLDNQNTLNTDP 1526
G N + IN G T D H++ E +N T + +N D
Sbjct 1355 GA--------ANAEVINTSGNIETTRGDITIRTGHLLNQREGINETKSYIPVENVAVPDG 1406
Query 1527 ANTSIQGIDANTLNVTSKVLNNQSGVIRSSADQ-NLNVQQALNNQSGQISSEKQLTLVGD 1585
AN+ + + + + SG D + ++ + ++ + G
Sbjct 1407 ANSVSVRVGDLGEDGWGYYVKSWSGTAGGGFDAWAVPTEKGATRKFLTGTTRVDVGATGG 1466
Query 1586 QLEINNLNGQILAGTALDLIAQSLSGDGKLLSLGNAKLSLQNDYIHSSGAQLQANQDLSL 1645
I+ N ++ LD L G +SL ++L+ Q+ + ++ Q + N
Sbjct 1467 DARISAGNNLLIDADKLDNTGSHLLASG-FVSLSGSQLNNQSFFGYT---QDEYNVYRYY 1522
Query 1646 STKGNIINNGTINAGNQLALNAANITNQQAGKIESHDT----RLTAQNTLNNTGLINGDF 1701
I N+G + G+ A + T A + + DT R Q N T + + D
Sbjct 1523 GKLAMIPNDGHLQYGDASADDRVTFTLSGAPEYVTRDTGQALRAVIQAGKNVTAVFSSDI 1582
Query 1702 TRLQAETLNNQGTGRIYGTTLAIQANT 1728
+ T GRI T A + NT
Sbjct 1583 ----SNTSTTSNAGRITNTLAAPEINT 1605
Score = 70.9 bits (172), Expect = 5e-14
Identities = 251/1287 (20%), Positives = 474/1287 (37%), Gaps = 246/1287 (19%)
Query 569 VKQAEIQTNSLSNQSGQLISNQKLNIQTQTANNQKGKIQSVDQLDLNVANGLNNIEGQIA 628
V + + ++ Q+G +IS Q +++ N + + + L ++ A+ L N+E
Sbjct 1827 VPEVYLSPKDVTLQNGSIISGQNVHLAGGNVTNSGSTLMAQNNLTIDSADSLGNLE---- 1882
Query 629 SGQQLNIQADQVNNQSGLIYSEQQGIELKANHAINNTSGIIQAKT-QLNLASTQLDNTS- 686
SGLI + + LKA INN S I KT +L + ++N +
Sbjct 1883 ---------------SGLI-NAGGALGLKAMGDINNISATITGKTVRLESLAGNVNNLTR 1926
Query 687 -GHIQAENIQQQHTTVNNTQGSIVAGQSLISTVDQFDNHQGLIDAKNIQLTHQVLNNSGS 745
H Q + + + GSI + +S +D D
Sbjct 1927 YSHWQLDAPEDSLALKHTYTGSIAS----VSAMDSLD----------------------- 1959
Query 746 IYADQNIKITGQHIL--NTGSIAAGQNIQLNTAKLQHEQAALIAAGLDRQGKLTSTGDLD 803
I AD+NI +TG I + ++ AG ++ LN + + R LT+
Sbjct 1960 IRADKNISVTGAEISAGDRAALIAGNDLSLNAIDRVSSRRHANSESHQRSAGLTT----- 2014
Query 804 ITAEQTTL--HGQSFAGQQLKVASKQQIDATNGQLQAKNIDLASDAGDISTRAATVIAEQ 861
ITA + + G+ + Q +A++ I G+ + + ++ TVI E
Sbjct 2015 ITAGDSVMLSAGRDVSSQGAGIAAEDNITVRAGRDVNLLAEESVTGSSSYSKKKTVIDET 2074
Query 862 LSLKSHDLIDNQQGTLSA-QQLNLTANRLDNTQGHILHTGQDQLDLNFSQSLNNQLGEIR 920
+ + ++ T++A + + A+ + T ++ G+D ++S + L +
Sbjct 2075 VRQQGAEIASGGDTTITAGRDITAVASSVTATGNISVNAGRDVALTTATESDYHYLETKK 2134
Query 921 SNAAELNIKTALLNNTEGQVVHAGTQQLNIQTAQLNGHLGHILSNGTLQLKAGTLDVSGG 980
+ L+ KT H +S + +AG L
Sbjct 2135 KSGGFLSKKTT-----------------------------HTISENSATREAGAL----- 2160
Query 981 VTSADQITIQANVLNNAQGQLIQRGTSNPLNLTIQQQLNNQAGLIQSATATDIKAGSLNN 1040
S +++T+ NA L +G+ + + N ++ +AT+TD
Sbjct 2161 -LSGNRVTV------NAGDNLTVQGSDVVADRDVSLAAGNHVDVL-AATSTDTSWRFKET 2212
Query 1041 QRGTLSSAQGQNLDVDVAGKLDNSQSGQIYAGNQAHLQVGSIDNSHQGQINAQQNLQLTS 1100
++ L G + + K + + +Q+ +GS N+ +T+
Sbjct 2213 KKSGLMGTGGIGFTIG-SSKTTHDRREAGTTQSQSASTIGS----------TAGNVSITA 2261
Query 1101 QQQINNQSGQIVANGDVQIQSQGLNNSHG------------QMGSLQGGLSLNTGS--DT 1146
+Q + ++AN D+ I + G + L LS GS +
Sbjct 2262 GKQAHISGSDVIANRDISITGDSVVVDPGHDRRTVDEKFEQKKSGLTVALSGTVGSAINN 2321
Query 1147 LINQSGLIQAKKDIGIQAQRIDNQQGQITTQGQAELISQAEIDNLEGAIAADLDVNIRSQ 1206
+ + + D ++A + GQA ++ A D A + +++ +Q
Sbjct 2322 AVTSAQETKESSDSRLKALQATKTALSGVQAGQAAAMATATGD----PNATGVSLSLTTQ 2377
Query 1207 GLNNNKGQISSAQGNLTLNAGNGTLTNQAATIVSGKTLTLSANQLDNSNHGQINSQNNAD 1266
+ + S TLNAG N + + +GK N G N D
Sbjct 2378 KSKSQQHSESDTVSGSTLNAG-----NNLSVVATGK------------NRG----DNRGD 2416
Query 1267 ISI----VKDINNTSGVIAAKQQLILSSQGLNNTTGQIGTVQGNLHIDAGSQLLNNQQGR 1322
I I +K NTS + AA L+ + TTG+ + G + + G+ +
Sbjct 2417 IVIAGSQLKAGGNTS-LDAANDILLSGAANTQKTTGRNSSSGGGVGVSIGA----GKGAG 2471
Query 1323 IQSGQDLNL-----NATGIDNTQGQISSKNQLQLDS-REQLLNNRQGTLSAENLTIDSGE 1376
I +N G + T+ S + ++S R+ +LN Q ++ + D G
Sbjct 2472 ISVFASVNAAKGSEKGNGTEWTETTTDSGKTVTINSGRDTVLNGAQ--VNGNRIIADVG- 2528
Query 1377 LNNDQGLIQAQQSIQIDTHQHNLSNTNSGAQGGILSQGNI------QLNNIQTLDNQQGY 1430
+D + Q + + D+ Q +++ S G + G I + ++ Q G
Sbjct 2529 --HDLLISSQQDTSKYDSKQTSVAAGGSFTFGSMTGSGYIAASRDKMKSRFDSVAEQTGM 2586
Query 1431 LASAQQLDLQANQVFNQNGTLLAA------KQLNLQGTGQNQLLN------NQSGQMLSM 1478
A D+ + +G ++A+ L+ G + L N + SG LS
Sbjct 2587 FAGDGGFDITVGRHTQLDGAVIASTATPDKNHLDTGTLGFSDLHNEADYKVSHSGISLSG 2646
Query 1479 GGM-------NLNIDQINNKGKANTADADSHIMAAGELNITTQQLDNQN----TLNTDP- 1526
GG N+ I+ G + A+ + A E IT + DNQ L+ DP
Sbjct 2647 GGSFGDKFQGNMPGGMISAGGHSGHAEGTTQ-AAVAEGTITIRDRDNQKQNPADLSRDPA 2705
Query 1527 -ANTSIQGI--------DANTLNVTSKVLNNQSGVIRSSADQNLNVQQALNNQSGQI--- 1574
AN SI I T+ + S + + + + R+ + LN +A +G+
Sbjct 2706 HANDSISPIFDKEKEQRRLQTVGLISDIGSQVADIARTQGE--LNALKAAKEATGETLPA 2763
Query 1575 -SSEKQ----LTLVGDQLEINNLNGQILAGTALDLIAQSLSGDGKLLSLGNAKLSLQNDY 1629
++EKQ L + D E + G+ + L Q+ + + L+ GN +L
Sbjct 2764 NATEKQRQEYLAKLRDTPEYKKEQEKYGTGSEIQLGIQAATAALQGLAGGNLAGALAGAS 2823
Query 1630 IHSSGAQLQANQ-DLSLSTKGNIINNGTINA--GNQLALNAAN-ITNQQAGKIESHDTRL 1685
L++ + D +++ + I G + A GN +A AA T + A +
Sbjct 2824 APELAHLLKSTEKDPAVNAIAHAILGGAVAAMQGNNVAAGAAGAATGELAAR-------- 2875
Query 1686 TAQNTLNNTGLINGDFTRLQAETLNNQGT------GRIYG---TTLAIQANTLNNQPDST 1736
A + G+ D + Q +T++ T G + G + A+ A + N D+
Sbjct 2876 -AIAGMLYPGVKQSDLSEEQKQTISTLATVSAGLAGGLTGNSSASAAVGAQSGKNAVDNN 2934
Query 1737 GTAPVIASRGDLHLGVQTLNNLSNPTD 1763
+ ++ + +L + QTL N NP +
Sbjct 2935 YLS--VSEKTELEIAKQTLKNSKNPAE 2959
Score = 69.7 bits (169), Expect = 1e-13
Identities = 253/1140 (22%), Positives = 412/1140 (36%), Gaps = 213/1140 (19%)
Query 2231 LKLDGDL----INGATIAGREALQITADNVQNLNGRIQGNQVAIETQKDLNNIGGQIIAK 2286
LK +GD+ ++ + G A +I + ++ G GN A E L++ G+++ K
Sbjct 232 LKGEGDVPKVAVDTGALGGMYARRIHLTSTESGVGVNLGNLYAREGDIILSS-SGKLVLK 290
Query 2287 DAMA----------------LKVGGNLNIESTTRTSESKVGNFSSSITNVDRV---AGLY 2327
+++A K GGNL++ TT + N S +T+ + V +G
Sbjct 291 NSLAGGNTTVTGTDVSLSGDNKAGGNLSVTGTTGLTL----NQSRLVTDKNLVLSSSGQI 346
Query 2328 VGNGSTKQLDPNQATLMLNVAGNSSLKGVQINNSNSA------TVLNTTGNVDL-GTVSV 2380
V NG L N+ L +N ++ A L TTG + L G
Sbjct 347 VQNGGE-----------LTAGQNAMLSAQHLNQTSGAVNAAENVTLTTTGGITLKGRSVA 395
Query 2381 GKQETLKIDD-KNGYQLKQQQDV---GSQIKSAGSLLINGQNITSKAVDLNSQQGDIQLS 2436
GK T+ NG L +D + G++ NG +T A DL S G I+
Sbjct 396 GKTLTVSSGSLNNGGTLGAGRDATVKTGTFSNTGAVQGNGLKVT--ATDLTS-TGSIKSG 452
Query 2437 AQKDIVLDNGLNQSTVSSQSQSKGSFGGKKSSTYDASSSTSIANQLNAGQNIIINSAQGN 2496
+ DI N +T+S G G K S+ S + +L + + +++ Q N
Sbjct 453 STLDISARN----ATLS------GDAGAKDSARVTVSGTLENRGRLVSDDVLTLSATQIN 502
Query 2497 ISATHLQAEAGNNIQIHAQQGNVTLLSAIDDKRESSTSSKKGVATYNNRQSGYIDQEVAQ 2556
S T A+ ++ A +T E S ++ G N+ S +
Sbjct 503 NSGTLSGAK-----ELVASADTLT-------TTEKSVTNSDGNLMLNSASSTLAGE---- 546
Query 2557 TTLKAGDTVDINAAKNIELQANDVQAGNSIYVGNTLMQRQADGSLKAADGSLMPENVTLS 2616
AG TV + +++ GNS+ V + Q DG+ A D +
Sbjct 547 --TSAGGTVSVK-GNSLKTTTTAQTQGNSVSV--DVQNAQLDGTQAARD---------IL 592
Query 2617 TLATKDEQWDEQQKGYRGIVKDIVKATAVGLAGIEALAPGLKAPKITVSESTGKRTEQIS 2676
TL ++ + + + T+ G+ +A L T++ S G + S
Sbjct 593 TLNASEKLTHSGKSSAPSLSLSAPELTSSGV----LVASALNTQSQTLTNS-GLLQGEAS 647
Query 2677 QTGSSLKADNVYVG---SSGQTTLTSTDITAKNTILLGQKVTLNAA---EEQKITVESTS 2730
T ++ + DN G S+ TL DI I +TLN A KIT ++ +
Sbjct 648 LTVNTQRLDNQQNGTLYSAADLTLDIPDIRNSGLITGDNGLTLNTASLSNPGKITADTLN 707
Query 2731 --KETVQGLGAKLNKDSIRLGGFVLEDASQSSKTT--------ETTHKLGSINTENLKIQ 2780
T+ G G ++ L G L S T +T + G+ +NL +Q
Sbjct 708 VRATTLDGDGLLQGAAALALAGDTLSQGSHGRWLTAGDLSLRGKTLNTAGTTQGQNLTVQ 767
Query 2781 -------------GVEGVDILGQNITATGDTLIDHGRGDLNVGGYENK-------TTVED 2820
G GQ +T+TGD ++ G LN +N+ T D
Sbjct 768 ADRWANSGSVLATGNLTASATGQ-LTSTGD-IMSQGDTTLNAATTDNRGSLLSAGTLSLD 825
Query 2821 KTHVETISTEVG---------VRNAYLDAALALGAVKDAAEAVKQAKDQYSQAQRDYASG 2871
++ T G N+ L+ G +A+ + + SQ ++G
Sbjct 826 GNSLDNSGTVQGNHVTLHHRSTDNSGTVTGLS-GLTLHSADGLTNSGALLSQNSLVLSAG 884
Query 2872 KITKEALDDSKANVAMATANLANAQIAVGSAAATAAASSATYGFTIGANGERIETTNTTN 2931
+T + N+ + ++L ++ AV SA A S G I A G +I
Sbjct 885 DVTNSGRIQGQ-NITLDASSLTSSG-AVQSALDLALTLS---GDVIAATGSKITALGDAR 939
Query 2932 TT------QGKWQGSTLELNNLTLKSENQDVNVQGSRLTATGTTSFDGTKDLNVTAGTEH 2985
T QG TLE+N +L + + V +T +G G +T G +
Sbjct 940 LTGKVLGNQGLISAKTLEVNGDSLSNSGEISGVNSLNVTLSGNLQQHGKM---LTGGALN 996
Query 2986 -SQQETSSKTNSQSVSYTYGGGGSASIGKQTSTSESKSLTYVNSEVTLNKTEGRLNSLNI 3044
+ ++ S+ Q A+ G+ S +LT +N+ N+T G L S N+
Sbjct 997 VNARDISNSGQLQGADNRITASSLANSGRVQGES-GLTLTLLNA--LTNQTSGVLLSQNV 1053
Query 3045 KGGEVSI-QDRGNLQVNNIHVESLQDTASSSNSSRGGSIGGGYGSGSKNITASYNQSKGS 3103
+ + G +Q N S A +S G + GG + + T Y
Sbjct 1054 SALSAPVLTNDGTIQGNGKTTLSAATQAHNS----GKILSGGELTFT---TPDY------ 1100
Query 3104 SDSAWVNTTSKL-----LIGN----AQNDANLDAMGVKNITNIGGVIANANKNA---DGS 3151
S S W+ T L L GN A N A L + N N N G+
Sbjct 1101 SGSGWLQATDLLLNVAKLAGNGTVMAANQATLTGNSLTNRGLFQAAQLNVNTQTITNSGT 1160
Query 3152 LTDHKNLNYTGNLELKDLQDHNNNNSSG--FNVSTNIGIPQGGSKAASTAPKGSTTI--- 3206
L ++ L GN N NN+ G F+ + S A G+ T+
Sbjct 1161 LLGNQGLTIKGN---------NLNNAGGKVFSGGDMLAEMVSLSGAGQLVALGNLTLKLT 1211
Query 3207 -GLNSSGQETEQLTKATLGQGSVTNA--------TADTNRDINNTQEITRDQTTGMLNGS 3257
GL + G + QG +TN T + + N ++T T L+GS
Sbjct 1212 RGLTAQGVIAANKQLSVSSQGDITNGATLQGNGITLNAAGRLTNNGQLTAGNGTTALSGS 1271
Score = 52.0 bits (123), Expect = 2e-08
Identities = 205/1048 (20%), Positives = 373/1048 (36%), Gaps = 108/1048 (10%)
Query 333 VRNAGSMNSTQSTLTLNANGDLTNTGNLIANQGQLQLNAENIKNTGNISSATSQVSLHSQ 392
VR G+ ++ T+ A D+T + + G + +NA ++ ++ S
Sbjct 2075 VRQQGAEIASGGDTTITAGRDITAVASSVTATGNISVNAG--RDVALTTATESDYHYLET 2132
Query 393 NLDNSGLISSADELNIQQQGHV--------GNRGTLNAA-RIVVDAGSLANSGSIEQTGA 443
+ G +S I + GNR T+NA + V + +
Sbjct 2133 KKKSGGFLSKKTTHTISENSATREAGALLSGNRVTVNAGDNLTVQGSDVVADRDVSLAAG 2192
Query 444 QALDLKAGSMSNIGGKIGIAKTSSTGGNGSESGGGSQPVEPNNAAQDGGSLEVVNTDSTP 503
+D+ A + ++ + K S G +GG + + D + S
Sbjct 2193 NHVDVLAATSTDTSWRFKETKKSGLMG----TGGIGFTIGSSKTTHDRREAGTTQSQSAS 2248
Query 504 TTPKTYETGYIHVRDQLNNDQGAIVAQGGIDLESNNGLDNQGGQLNLGRVKIQGERFNND 563
T T I Q + ++A I + ++ + + G + E+F
Sbjct 2249 TIGSTAGNVSITAGKQAHISGSDVIANRDISITGDSVVVDPGHDR-----RTVDEKFEQK 2303
Query 564 QGQLTVKQAEIQTNSLSN-----QSGQLISNQKLNIQTQTANNQKGKIQSVDQLDLNVAN 618
+ LTV + ++++N Q + S+ +L T G +Q+ + A
Sbjct 2304 KSGLTVALSGTVGSAINNAVTSAQETKESSDSRLKALQATKTALSG-VQAGQAAAMATAT 2362
Query 619 GLNNIEGQIASGQQLNIQADQVNNQSGLIYSEQQGIELKANHAI----------NNTSGI 668
G N A+G L++ + +Q G L A + + +N I
Sbjct 2363 GDPN-----ATGVSLSLTTQKSKSQQHSESDTVSGSTLNAGNNLSVVATGKNRGDNRGDI 2417
Query 669 IQAKTQLNL-ASTQLDNTSGHIQAENIQQQHTTVNNTQG------SIVAGQSL-ISTVDQ 720
+ A +QL +T LD + + + Q TT N+ SI AG+ IS
Sbjct 2418 VIAGSQLKAGGNTSLDAANDILLSGAANTQKTTGRNSSSGGGVGVSIGAGKGAGISVFAS 2477
Query 721 FDNHQGLIDAKNIQLTH-------QVLNNSGSIYADQNIKITGQHILNTGSIAAGQNIQL 773
+ +G + T V NSG ++ G I+ + Q
Sbjct 2478 VNAAKGSEKGNGTEWTETTTDSGKTVTINSGRDTVLNGAQVNGNRIIADVGHDLLISSQQ 2537
Query 774 NTAKLQHEQAALIAAGLDRQGKLTSTGDLDITAEQTTLHGQSFAGQQLKVASKQQIDATN 833
+T+K +Q ++ A G G +T +G + + ++ S A Q A D T
Sbjct 2538 DTSKYDSKQTSVAAGGSFTFGSMTGSGYIAASRDKMKSRFDSVAEQTGMFAGDGGFDITV 2597
Query 834 GQ-LQAKNIDLASDAG------DISTRAATVIAEQLSLK-SHDLIDNQQGTLSAQ--QLN 883
G+ Q +AS A D T + + + K SH I G Q N
Sbjct 2598 GRHTQLDGAVIASTATPDKNHLDTGTLGFSDLHNEADYKVSHSGISLSGGGSFGDKFQGN 2657
Query 884 LTANRLDNTQGHILHT-GQDQLDLNFSQSLNNQLGEIRSNAAELNIKTALLNNTEGQVVH 942
+ + + GH H G Q + + N A+L+ A N++ +
Sbjct 2658 MPGGMI-SAGGHSGHAEGTTQAAVAEGTITIRDRDNQKQNPADLSRDPAHANDSISPIFD 2716
Query 943 AGTQQLNIQTAQLNGHLGHILSNGTLQLKAGTLDVSGGVTSADQITIQANVLNNAQGQLI 1002
+Q +QT L +G +++ + G L+ A T+ AN + + +
Sbjct 2717 KEKEQRRLQTVGLISDIGSQVAD--IARTQGELNALKAAKEATGETLPANATEKQRQEYL 2774
Query 1003 QRGTSNPLNLTIQQQLNNQAGL---IQSATATDIKAGSLNNQRGTLSSAQGQNL------ 1053
+ P Q++ + + IQ+ATA ++ + N G L+ A L
Sbjct 2775 AKLRDTPEYKKEQEKYGTGSEIQLGIQAATAA-LQGLAGGNLAGALAGASAPELAHLLKS 2833
Query 1054 -DVDVA-GKLDNSQSGQIYAGNQAHLQVGSIDNSHQGQINAQQNLQL----TSQQQINNQ 1107
+ D A + ++ G A Q + + G++ A+ + Q ++ +
Sbjct 2834 TEKDPAVNAIAHAILGGAVAAMQGNNVAAGAAGAATGELAARAIAGMLYPGVKQSDLSEE 2893
Query 1108 SGQIVANGDVQIQSQGLNNSHGQMGSLQGGLSLNTGSDTLINQSGLIQAKKDIGIQAQRI 1167
Q ++ + S GL S + +G + + N + K ++ I Q +
Sbjct 2894 QKQTIST--LATVSAGLAGGLTGNSSASAAVGAQSGKNAVDNNYLSVSEKTELEIAKQTL 2951
Query 1168 DNQQGQITTQGQAELISQAEIDNLEGAIAADLDVNIRSQGLNNNKGQISSAQGNLTLNAG 1227
N + + E Q LE IA+D +V I + G N N G + A L + A
Sbjct 2952 KNSK----NPAEREKAQQKYDALLEKDIASDKEV-IAACG-NGNAGSSACASARLKVIAS 3005
Query 1228 NGTLTNQAATIVSGKTLTLSANQLDNSNHGQINSQNNADISIVKDINNTSGVIAAKQQLI 1287
+ G + + Q ++ +GQI N DI+ V D+ N V A
Sbjct 3006 KEGYED-------GPYNSKYSQQYADA-YGQI--VNLLDITSV-DVQNQQQVKDAMVSYF 3054
Query 1288 LSSQGLNNTT--GQIGTVQGNLHIDAGS 1313
+++ G++ T G + T QG L I A S
Sbjct 3055 MATLGVDQKTAQGYVETTQG-LEIAAAS 3081
Score = 40.8 bits (94), Expect = 6e-05
Identities = 136/693 (20%), Positives = 264/693 (38%), Gaps = 89/693 (13%)
Query 330 GVGVRNAGSMNSTQSTLTLNANGDLTN-TGNLIANQGQLQLNA----ENIKNT------- 377
G V N+GS Q+ LT+++ L N LI G L L A NI T
Sbjct 1854 GGNVTNSGSTLMAQNNLTIDSADSLGNLESGLINAGGALGLKAMGDINNISATITGKTVR 1913
Query 378 -----GNISSAT-----------SQVSLHSQNLDNSGLISSADELNIQQQGHVGNRGTLN 421
GN+++ T ++L + +S+ D L+I+ ++ G
Sbjct 1914 LESLAGNVNNLTRYSHWQLDAPEDSLALKHTYTGSIASVSAMDSLDIRADKNISVTGAEI 1973
Query 422 AA--RIVVDAGSLANSGSIEQTGAQALDLKAGSMSNIGGKIGIAKTSS---TGGNGSESG 476
+A R + AG+ + +I++ ++ + S G I S + G S
Sbjct 1974 SAGDRAALIAGNDLSLNAIDRVSSRR-HANSESHQRSAGLTTITAGDSVMLSAGRDVSSQ 2032
Query 477 GGSQPVEPNNAAQDGGSLEVVNTDSTPTTPKTYETGYIHVRDQLNNDQGAIVAQGGIDLE 536
G E N + G + ++ +S T +Y V D+ QGA +A GG D
Sbjct 2033 GAGIAAEDNITVRAGRDVNLLAEESV-TGSSSYSKKKT-VIDETVRQQGAEIASGG-DTT 2089
Query 537 SNNGLDNQGGQLNL---GRVKIQGERFNNDQGQLTVKQAEIQTNSLSNQSGQLISNQKLN 593
G D ++ G + + R D T +++ +SG +S + +
Sbjct 2090 ITAGRDITAVASSVTATGNISVNAGR---DVALTTATESDYHYLETKKKSGGFLSKKTTH 2146
Query 594 -IQTQTANNQKGKIQSVDQLDLNVANGLNNIEG---------QIASGQQLNIQAD----- 638
I +A + G + S +++ +N + L ++G +A+G +++ A
Sbjct 2147 TISENSATREAGALLSGNRVTVNAGDNL-TVQGSDVVADRDVSLAAGNHVDVLAATSTDT 2205
Query 639 ----QVNNQSGLIYSEQQGIELKANHAINNTSGIIQAKTQLNLASTQLDNTSGHIQAENI 694
+ +SGL+ + G + ++ ++ +A T + +++ + +T+G++
Sbjct 2206 SWRFKETKKSGLMGTGGIGFTIGSSKTTHDRR---EAGTTQSQSASTIGSTAGNVSITAG 2262
Query 695 QQQH---TTVNNTQGSIVAGQSLISTVDQFDNHQGLIDAKNIQLTHQVLNNSGSIYADQN 751
+Q H + V + + G S++ VD + + + + + + + SG++ + N
Sbjct 2263 KQAHISGSDVIANRDISITGDSVV--VDPGHDRRTVDEKFEQKKSGLTVALSGTVGSAIN 2320
Query 752 IKITGQHILNTGSIAAGQNIQLNTAKLQHEQAALIAAGLDRQGKLTSTGDLDITAEQTTL 811
+T S + + +Q L QA AA T+TGD + T +L
Sbjct 2321 NAVTSAQETKESSDSRLKALQATKTALSGVQAGQAAA------MATATGDPNATGVSLSL 2374
Query 812 HGQSFAGQQLKVASKQQIDATNGQLQAKNIDLASDAGDISTRAATVIA-EQLSLKSHDLI 870
Q QQ + N + + GD R VIA QL + +
Sbjct 2375 TTQKSKSQQHSESDTVSGSTLNAGNNLSVVATGKNRGD--NRGDIVIAGSQLKAGGNTSL 2432
Query 871 DNQQGTL--SAQQLNLTANRLDNTQGHI---LHTGQDQLDLNFSQSLNNQLGEIRSNAAE 925
D L A T R ++ G + + G+ ++ S+N G + N E
Sbjct 2433 DAANDILLSGAANTQKTTGRNSSSGGGVGVSIGAGKG-AGISVFASVNAAKGSEKGNGTE 2491
Query 926 LNIKTALLNNTEGQVVHAGTQQLNIQTAQLNGH 958
T ++ + +++G + + AQ+NG+
Sbjct 2492 WTETTT--DSGKTVTINSGRDTV-LNGAQVNGN 2521
Score = 35.8 bits (81), Expect = 0.002
Identities = 79/394 (20%), Positives = 142/394 (36%), Gaps = 66/394 (17%)
Query 595 QTQTANNQKGKIQSVDQLDLNVANGLNNIEGQIASGQQLNIQADQVNNQSGLIYSEQQGI 654
Q+ + QK I ++ + +A GL A+ V QSG
Sbjct 2887 QSDLSEEQKQTISTLATVSAGLAGGLTGNSSASAA----------VGAQSG--------- 2927
Query 655 ELKANHAINNTSGIIQAKTQLNLASTQLDNTSGHIQAENIQQQHTTVNNTQGSIVAGQSL 714
+A++N + KT+L +A L N+ + E QQ++ + + I + + +
Sbjct 2928 ----KNAVDNNYLSVSEKTELEIAKQTLKNSKNPAEREKAQQKYDAL--LEKDIASDKEV 2981
Query 715 ISTVDQFDNHQGLIDAKNIQLTHQVLNNSG-------SIYADQNIKITGQ--HILNTGSI 765
I+ + + +++ + + G S Y+ Q GQ ++L+ S+
Sbjct 2982 IAACGNGNAGSSACASARLKV---IASKEGYEDGPYNSKYSQQYADAYGQIVNLLDITSV 3038
Query 766 AAGQNIQLNTAKLQHEQAALIAAGLDRQGKLTSTGDLDI-TAEQTTLHGQSFA------- 817
Q+ A + + A L QG + +T L+I A T L GQ+ A
Sbjct 3039 DVQNQQQVKDAMVSYFMATLGVDQKTAQGYVETTQGLEIAAASMTPLFGQAVANKITALV 3098
Query 818 --------GQQLKVASKQQIDATNGQLQAKNIDLASDAGDISTRAATVIAEQLSLKSHDL 869
G K+ + + +G Q K I A +A D+ +A V+ + + S +
Sbjct 3099 DKANKYPSGIGFKINQPEHLAQLDGYSQKKGISGAHNA-DVFNKA--VVDNGVKIIS-ET 3154
Query 870 IDNQQGTLSAQQLNLTANRLDNTQGHILHTGQDQLDLN------FSQSLNNQLGEIRSNA 923
+G Q T + NT G+ G + F+ QLG+ A
Sbjct 3155 PTGVRGITQVQYEIPTKDAAGNTTGNYKGNGAKPFEKTIYDPKIFTDEKMLQLGQ---EA 3211
Query 924 AELNIKTALLNNTEGQVVHAGTQQLNIQTAQLNG 957
A + A+ N + AG + Q G
Sbjct 3212 AAIGYSNAIKNGLQAYDAKAGGVTFRVYIDQKTG 3245
Score = 34.7 bits (78), Expect = 0.004
Identities = 109/490 (22%), Positives = 166/490 (34%), Gaps = 57/490 (12%)
Query 2900 GSAAATAAASSATYGFTIGANGERIETTNTTNTTQGKWQGSTLELNNLTLKSENQDVN-- 2957
G AA A+ YG T G I T T TT + L L + + +N
Sbjct 130 GKAANVMVANP--YGITCDGCGF-INTPRATLTTGRPVMNADGSLQALEVTEGSITINGA 186
Query 2958 -VQGSR-------LTATGTTSFDGTKDLNVTAGTEHSQQETSSKTNSQSVSYTYGGGGSA 3009
+ G+R AT + KDL VTAG T VS G G
Sbjct 187 GLDGTRSDAVSIIARATEVNAALHAKDLTVTAGANRV-------TADGRVSALKGEGDVP 239
Query 3010 SIGKQTSTSESKSLTYVNSEVTLNKTEGRLNSLNIKGGEVSIQDRGNLQVNNIHVESLQD 3069
+ T ++ T + L +L + G++ + G L + N
Sbjct 240 KVAVDTGALGGMYARRIHLTSTESGVGVNLGNLYAREGDIILSSSGKLVLKNSLAGGNTT 299
Query 3070 TASSSNSSRGGSIGGGYGSGSKNITASYNQSKGSSDSAWVNTTSKLLIGN-----AQNDA 3124
+ S G + GG S + + NQS+ +D V ++S ++ N A +A
Sbjct 300 VTGTDVSLSGDNKAGGNLSVTGTTGLTLNQSRLVTDKNLVLSSSGQIVQNGGELTAGQNA 359
Query 3125 NLDAMGVKNITNIGGVIANANKNADGSLTDHKNLNYTGNLELKDLQDHNNNNSSG----- 3179
L A + + N G +T K + G NN + G
Sbjct 360 MLSAQHLNQTSGAVNAAENVTLTTTGGIT-LKGRSVAGKTLTVSSGSLNNGGTLGAGRDA 418
Query 3180 ---FNVSTNIGIPQG-GSKAASTAPKGSTTIGLNSSGQETE-QLTKATLG--QGSVTNAT 3232
+N G QG G K +T T+ G SG + ATL G+ +A
Sbjct 419 TVKTGTFSNTGAVQGNGLKVTAT---DLTSTGSIKSGSTLDISARNATLSGDAGAKDSAR 475
Query 3233 ADTNRDINNTQEITRDQTTGMLNGSVTVDHRLLSESGRAEIVKEQEQLIENFRQSAENLA 3292
+ + N + D +L S T + + SG E+V SA+ L
Sbjct 476 VTVSGTLENRGRLVSDD---VLTLSATQINNSGTLSGAKELV-----------ASADTLT 521
Query 3293 KALPDGVYKDKALQTLNDVQAKLYNLPSEYKEVGVVGNSVASELLKRGM-ESQDVEALFS 3351
D L LN + L S V V GNS+ + + S V+ +
Sbjct 522 TTEKSVTNSDGNLM-LNSASSTLAGETSAGGTVSVKGNSLKTTTTAQTQGNSVSVDVQNA 580
Query 3352 KLDFFYAAKE 3361
+LD AA++
Sbjct 581 QLDGTQAARD 590
Score = 26.6 bits (57), Expect = 1.1
Identities = 91/439 (21%), Positives = 151/439 (34%), Gaps = 64/439 (15%)
Query 133 DVGQEGAILNNARNNTQTQLGGWIQGNPWLAKGEAKVILNEVNSSNPSQLKGYIEVAGKQ 192
D G + ++ ++ L + G A A E S+ S+LK ++
Sbjct 2288 DPGHDRRTVDEKFEQKKSGLTVALSGTVGSAINNAVTSAQETKESSDSRLKA-LQATKTA 2346
Query 193 AQVVIANPSGLVCDGCGVINADRFTLT-TGQAVMNQGYLESFRVREGQITIQGKGLNGSL 251
V A + + G NA +L+ T Q +Q + ES V G G L+
Sbjct 2347 LSGVQAGQAAAMATATGDPNATGVSLSLTTQKSKSQQHSESDTV-SGSTLNAGNNLSVVA 2405
Query 252 TPFT------DVYARALQVNAGLYAKELNVVLGQNDINV-NDPTTSNVSPIQSNTSANNK 304
T D+ Q+ AG G ++ ND S + Q T N+
Sbjct 2406 TGKNRGDNRGDIVIAGSQLKAG----------GNTSLDAANDILLSGAANTQKTTGRNSS 2455
Query 305 PQFALDVGQLGGMYAG-KIFLV-----GTEQGVGVRNAGSMNSTQSTLTLNA------NG 352
+ V G AG +F G+E+G G + + T+T+N+ NG
Sbjct 2456 SGGGVGVSIGAGKGAGISVFASVNAAKGSEKGNGTEWTETTTDSGKTVTINSGRDTVLNG 2515
Query 353 DLTNTGNLIANQGQ---LQLNAENIKNTGNISSATSQVSLHSQNLDNSGLI-SSADELN- 407
N +IA+ G + + K +S + S ++ SG I +S D++
Sbjct 2516 AQVNGNRIIADVGHDLLISSQQDTSKYDSKQTSVAAGGSFTFGSMTGSGYIAASRDKMKS 2575
Query 408 -----IQQQG----------HVGNRGTLNAARIV---------VDAGSLANSGSIEQTGA 443
+Q G VG L+ A I +D G+L S +
Sbjct 2576 RFDSVAEQTGMFAGDGGFDITVGRHTQLDGAVIASTATPDKNHLDTGTLGFSDLHNEADY 2635
Query 444 QALDLKAGSMSNIGGKIGIAKTSSTGGNGSESGGGSQPVE-PNNAAQDGGSLEVVNTDST 502
+ +G + GG G + G +GG S E AA G++ + + D+
Sbjct 2636 KV--SHSGISLSGGGSFGDKFQGNMPGGMISAGGHSGHAEGTTQAAVAEGTITIRDRDNQ 2693
Query 503 PTTPKTYETGYIHVRDQLN 521
P H D ++
Sbjct 2694 KQNPADLSRDPAHANDSIS 2712
>P0DSI1 tRNA nuclease CdiA [Escherichia coli (strain NC101)]
Length=3289
Score = 368 bits (944), Expect = 4e-104
Identities = 428/1571 (27%), Positives = 653/1571 (42%), Gaps = 282/1571 (18%)
Query 107 SSNGVTQVNIQTPSAGGVSRNTYSQFDVGQEGAILNNARNNTQ-TQLGGWIQGNPWL-AK 164
++NGV VNI TP G+S N ++ ++VG+EG ILNNA TQLGG IQ NP L A
Sbjct 45 AANGVPVVNIATPDGAGISHNRFTDYNVGKEGLILNNATGKLNPTQLGGLIQNNPNLKAG 104
Query 165 GEAKVILNEVNSSNPSQLKGYIEVAGKQAQVVIANPSGLVCDGCGVINADRFTLTTGQAV 224
GEAK I+NEV N S L+GY EVAGK A V++ANP G+ CDGCG IN TLTTG+ V
Sbjct 105 GEAKGIINEVTGGNRSLLQGYTEVAGKAANVMVANPYGITCDGCGFINTPHATLTTGRPV 164
Query 225 MN-QGYLESFRVREGQITIQGKGLNGSLTPFTDVYARALQVNAGLYAKELNVVLGQNDIN 283
MN G L++ V EG ITI G GL+G+ + + ARA +VNA L+AK+L V G N I
Sbjct 165 MNADGSLQALEVTEGSITINGAGLDGTRSDAVSIIARATEVNAALHAKDLTVTAGANRIT 224
Query 284 VNDPTTSNVSPIQSNTSANNKPQFALDVGQLGGMYAGKIFLVGTEQGVGVRNAGSMNSTQ 343
+ VS ++ + P+ A+D G LGGMYA +I L TE GVGV N G++ +
Sbjct 225 AD----GRVSALKGE---GDVPKVAVDTGALGGMYARRIHLTSTESGVGV-NLGNLYARD 276
Query 344 STLTLNANGDLTNTGNL----IANQGQLQLNAENIKNTGNIS------------------ 381
+TL+A+G LT +L + +GQ + K GN+S
Sbjct 277 GDITLDASGRLTVNNSLATGAVTAKGQGVTLTGDHKAGGNLSVSSRSDIVLSNGTLNSDK 336
Query 382 -----------------SATSQVSLHSQNL--DNSGLIS--------SADELNIQQQGHV 414
+A V+L ++N+ D + I+ S+D L Q Q
Sbjct 337 DLSLTAGGRITQQNEKLTAGRDVTLAAKNITQDTASQINAARDIVTVSSDTLTTQGQITA 396
Query 415 GNRGTLNAARIV------------VDAGSLANSGSIEQTGAQALDLKAGSMSNIG----- 457
G T +A + +DAG+L NSG+++ +L L + ++SN G
Sbjct 397 GQNLTASATTLTQDGTLLAKGHAGLDAGTLNNSGAVQ---GASLTLGSTTLSNSGSLLSG 453
Query 458 -------------------GKIGI---AKTSSTGG----------------NGSESGGGS 479
GK+ I K +STG NG SGG
Sbjct 454 GPLTVNTRDFTQSGRTGAKGKVDITASGKLTSTGSLVSDDVLVLKAQDVTQNGVLSGGKG 513
Query 480 QPVEPNNAAQDGGSLEVVNTDSTPTTPKTYET--GYIHVRDQLNNDQGAIVAQGGIDLES 537
V A G V ++D+ T T G D L + G L+S
Sbjct 514 LTVSAQ--ALSSGKKSVTHSDAAMTLNVTTVALDGENSAGDTLRVQADKLSTAAGAQLQS 571
Query 538 NNGLDNQGGQLNLGRVKIQGERFNNDQGQLTVKQAEIQTNSLSNQSGQLISN-----QKL 592
L L + + + + + SLS + +L S+ L
Sbjct 572 GKNLSINARDARLAGTQAAQQTMAVNASEKLTHSGKSSAPSLSLSAPELTSSGVLVGSAL 631
Query 593 NIQTQTANNQKGKIQSVDQLDLNVANGLNNIEGQIASGQQLNIQADQVNNQSGLIYSEQQ 652
N Q+QT N G +Q L +N N G + S L + + N SGLI +
Sbjct 632 NTQSQTLTN-SGLLQGEASLTVNTQRLDNQQNGTLYSAADLTLDIPDIRN-SGLITGDN- 688
Query 653 GIELKANHAINNTSGIIQAKTQLNLASTQLD----------------------------- 683
L N A + G I A T LN+ +T LD
Sbjct 689 --GLTLNTASLSNPGKIIADT-LNVRATTLDGDGLLQGAGALALAGDTLSQGRNGRWLTA 745
Query 684 ----------NTSGHIQAENIQQQHTTVNNTQGSIVAGQSLISTVDQFDNHQGLIDAKNI 733
+T+G Q +N+ Q N+ + G S Q + ++ +
Sbjct 746 GDLSLRGKTLHTAGTTQGQNLTVQADNWANSGSVLATGNLTASATGQLTSTGDIMSQGDT 805
Query 734 QLTHQVLNNSGSIYADQNIKITGQHILNTGSIAAG-----QNIQLNTAKLQHEQAALIAA 788
L +N GS+ + + + G + N G++ QN N+ L A +AA
Sbjct 806 TLNAATTDNRGSLLSAGTLSLDGNSLDNRGTVQGNHVTIRQNSVTNSGTLTGIAALTLAA 865
Query 789 GLD----------RQGKLTSTGDLDITAEQTTLHGQSFAGQQLKVASKQQIDATNGQLQA 838
+D G L ++GDL ITA T G + G+Q+ + + A +G +QA
Sbjct 866 RMDMASPQPALMNNGGSLLTSGDLTITAGSITSSGH-WQGKQVLITADSL--ANSGAIQA 922
Query 839 KNIDLASDAGDISTRAATVIAEQLSLKSHDLIDNQQGTLSAQQLNLTANRLDNTQGHILH 898
+ A G++ + A + + + L + G A+ L L AN L + G I
Sbjct 923 ADSLTARLTGELVSTAGSKVTSNGEMALSALNLSNSGQWIAKNLTLKANSL-TSAGDI-- 979
Query 899 TGQDQLDLNFSQSLNNQLGEIRSNAAELNIKTALLNN-----------TEGQVVHAGTQQ 947
TG D L L +Q+LNN +A L +K + N T GQ+ + G Q
Sbjct 980 TGVDALTLTVNQTLNNHASGKLLSAGVLTLKADSVKNDGQLQGNATTITAGQLTNGGHLQ 1039
Query 948 LNIQTAQLNGHL-----GHILSNGTLQLKAGTLDVSGGVTSADQITIQANVLNNAQGQLI 1002
T +G + G ++S L + TL G + +++ A G+++
Sbjct 1040 GETLTLTASGGVNNRSGGVLMSRNALNVSTATLSNQGTIQGGGGVSLNATDRLQNDGKIL 1099
Query 1003 QRGTSNPLNLTIQQQLNNQAGLIQSAT------------------ATDIKAGSLNNQRGT 1044
+ + L LT Q N +GL+Q+AT + D+K +LNN GT
Sbjct 1100 ---SGSNLTLTAQVLANTGSGLVQAATLLLDVVNTVNGGRVLATGSADVKGTTLNN-TGT 1155
Query 1045 LSSAQGQNLDVDVAGKLDNSQSGQIYAGNQAHLQVGSIDNSHQGQINAQQNLQLTSQQQI 1104
L QG +L V+ S SG + + ++ S+ + G++ + NL L +Q
Sbjct 1156 L---QGADLLVNYH---TFSNSGTLLGTSGLGVKGSSLLQNGTGRLYSAGNLLLDAQD-- 1207
Query 1105 NNQSGQIVANGDVQIQSQGLNNSHGQMGSLQGGLSLNTGSDTLINQSGLIQAKKDIGIQA 1164
+ GQ+VA GDV ++ +H G+L G +L+ S I G++Q +
Sbjct 1208 FSGQGQVVATGDVTLKLIAALTNH---GTLAAGKTLSVTSQNAITNGGVMQGDAMVLGAG 1264
Query 1165 QRIDNQQGQITTQGQAELISQAEIDNLEGAIAADLDVNIRSQGLNNNKGQISSAQGNLTL 1224
+ N +G + +Q N G++ A DV++ S+ G +A G+LT+
Sbjct 1265 EAFTNNGMLTAGKGNSVFSAQRLFLNAPGSLQAGGDVSLNSRSDITISGFTGTA-GSLTM 1323
Query 1225 NAGNGTLTNQAATIVSGKTLTLSANQLDNSNHGQINSQNNADISIVKDINNTSGVIAAKQ 1284
N GTL N +A I +G L L ++L N HG I + N+ + + KD + A
Sbjct 1324 NVA-GTLLN-SALIYAGNNLKLFTDRLHN-QHGDILAGNS--LWVQKDASG-----GANT 1373
Query 1285 QLILSSQGLNNTTGQIGTVQGNLHIDAGSQLLNNQQGRIQSGQDLNLNATGIDNTQ-GQI 1343
++I NT+G I T QG++ + G LLN ++G +AT T I
Sbjct 1374 EII-------NTSGNIETHQGDIVVRTG-HLLNQREG---------FSATTTTRTNPSSI 1416
Query 1344 SSKNQLQLDSREQLLNNRQGTLSAENLTIDSGELNNDQGLIQAQQSIQIDTHQHNLSNTN 1403
+D LL + + G N G +I +DT + +
Sbjct 1417 QGMGNALVDIPLSLLPDGSYGYFTREVENQHGTPCNGHGAC----NITMDTLYYYAPFAD 1472
Query 1404 SGAQGGILSQGNIQLNNIQTLDNQQGYLASAQQLDLQANQVFNQNGTLLAAKQLNLQGTG 1463
S Q + SQ + + DN G +AS + L +A ++ N+ +LA + L G
Sbjct 1473 SATQRFLSSQ---NITTVTGADNPAGRIASGRNLSAEAERLENRASFILANGDIALSG-- 1527
Query 1464 QNQLLNNQSGQ 1474
+ L+NQS Q
Sbjct 1528 --RELSNQSWQ 1536
Score = 221 bits (562), Expect = 2e-59
Identities = 304/1217 (25%), Positives = 506/1217 (42%), Gaps = 208/1217 (17%)
Query 2086 ETDPAFADYKKWLSSDYMLDALGLDPALQQKRLGDGFYEQRLVQDQIANLTGYRFLEGFA 2145
ET P++ D K++L S Y LD LGL P + LGD ++ R V + + + TG R+L G
Sbjct 1746 ETAPSYTDEKQFLGSSYFLDRLGLKPEKDYRFLGDAVFDTRYVSNAVLSRTGSRYLNGLG 1805
Query 2146 NDDEQYKALMNNGITFAKLYGLRPGIALTAAQTAQLTSDIVWLVEQSVTLPDGTITKALV 2205
+D EQ + LM+N K GL G+ALTA Q AQL I+W +S T+ T+ +V
Sbjct 1806 SDTEQMRYLMDNAARQQKGLGLEFGVALTAEQIAQLDGSILWW--ESATINGQTV---MV 1860
Query 2206 PQVYVKVRVGDLKGDGTLLSGNSVNLKLDGDLINGATIAGREALQITADN-VQNLNGRI- 2263
P++Y+ L +G+++SGN+V L +G +I + L + + + NLN +
Sbjct 1861 PKLYLSPEDITLH-NGSVISGNNVQLAGGNITNSGGSINAQNGLSLDSTGYIDNLNAGLI 1919
Query 2264 -QGNQVAIETQKDLNNIGGQIIAKDAMALKVGGNLNIESTTRTSESKVGNFSSSITNVDR 2322
G + + D++NI I K V G NI + TR + G+ S R
Sbjct 1920 SAGGSLDLSAIGDISNISSVISGKTVQLESVSG--NISNITRRQQWNAGSDS-------R 1970
Query 2323 VAGLYVGNGSTKQLDPNQAT--LMLNVAGNSSLKGVQINNSNSATVLNTTG---NVDLGT 2377
G+++ T + + T L L+ N + G + S+ T+ + G N+
Sbjct 1971 YGGVHLSGTDTGPVATIKGTDSLSLDAGKNIDITGATV--SSGGTLGMSAGNDINIAANL 2028
Query 2378 VSVGKQET--LKIDDKNGYQLKQQQDVGSQIKSAGSL-LINGQNITSKAVDLNSQQGDIQ 2434
+S K ++ DD + Q GS I + G+L + G N+ A +++ +
Sbjct 2029 ISGSKSQSGFWHTDDNSASSTTSQ---GSSISAGGNLAMAAGHNLDVTASSVSAGHSAL- 2084
Query 2435 LSAQKDIVLDNGLNQSTVSSQSQSKGSFGGKKSSTYDASSSTSIANQLNAGQNIIINSAQ 2494
LSA D+ ++++ +SK S G+ S S + + + AG N+++ + +
Sbjct 2085 LSAGNDL---------SLNAVRESKNSRNGRSES----HESHAAVSTVTAGDNLLLVAGR 2131
Query 2495 GNISATHLQAEAGNNIQIHAQQGNVTLLSAIDDKRESSTSSKKGVATYNNRQSGYIDQEV 2554
++++ A NN+ I + +V L++ +S TS KK RQ G
Sbjct 2132 -DVASQAAGVAAENNVVIRGGR-DVNLVAESAGAGDSYTSKKKKEINETVRQQG------ 2183
Query 2555 AQTTLKAGDTVDINAAKNIELQANDVQAGNSIYVGNTLMQRQADGSLKAADGSLMPENVT 2614
T + +G +NA ++I A+ V A +I V +V
Sbjct 2184 --TEIASGGDTTVNAGRDITAVASSVTATGNISVN-------------------AGRDVA 2222
Query 2615 LSTLATKDEQWDEQQKGYRGIVKDIVKATAVGLAGIEALAPGLKAPKITVSESTGKRTEQ 2674
L+T D + E +K G + K T+SE + R
Sbjct 2223 LTTATESDYHYLETKKKSGGFLS--------------------KKTTHTISEDSASR--- 2259
Query 2675 ISQTGSSLKADNVYVGSSGQTTLTSTDITAKNTILL--GQKVTLNAAEEQKIT--VESTS 2730
+ GS L + V V + T+ +D+ A + L G V + AA + + T
Sbjct 2260 --EAGSLLSGNRVTVNAGDNLTVEGSDVVADQDVSLAAGNHVDVLAATSTDTSWRFKETK 2317
Query 2731 KETVQGLG--------AKLNKDSIRLGGFVLEDASQSSKTTETTHKLGSINTENLKIQGV 2782
K + G G +K D G SQS+ T +T G+++ K +
Sbjct 2318 KSGLMGTGGIGFTIGSSKTTHDRREAG----TTQSQSASTIGST--AGNVSITAGKQAHI 2371
Query 2783 EGVDIL-GQNITATGDTLIDHGRGDLNVGGYENKTTVEDKTHVETISTEVGVRNAYLDAA 2841
G D++ ++I+ TGD+++ V ++ TV++K + V +
Sbjct 2372 SGSDVIANRDISITGDSVV--------VDPGHDRRTVDEKFEQKKSGLTVALSGT---VG 2420
Query 2842 LALGAVKDAAEAVKQAKDQYSQAQRDYASGKITKEALDDSKANVAMATANLANAQIAVGS 2901
A+ +A+ K++ D +A + TK AL +A A A A A G
Sbjct 2421 SAINNAVTSAQETKESSDSRLKAL------QATKTALSGVQAGQAAAMAT------ATGD 2468
Query 2902 AAATAAASSATYGFTIGANGERIETTNTTNTTQGKWQGSTLEL-NNLTL------KSENQ 2954
AT + S T T + ++ ++T + GSTL NNL++ + +N+
Sbjct 2469 PNATGVSLSLT---TQKSKSQQHSESDTVS-------GSTLNAGNNLSVVATGKNRGDNR 2518
Query 2955 -DVNVQGSRLTATGTTSFDGTKD--LNVTAGTEHSQQETSSKTNSQSVSYTYGGGG---- 3007
D+ + GS+L A G TS D D L+ A T+ + SS VS GG G
Sbjct 2519 GDIVIAGSQLKAGGNTSLDAANDVLLSGAANTQKTTGRNSSSGGGVGVSIGAGGNGAGIS 2578
Query 3008 -----SASIGKQTSTSESKSLTYVNSEVTLNKTEGR---LNSLNIKGGEVSIQDRGNLQV 3059
+A+ G + + T ++S T+ GR LN + G + I D G
Sbjct 2579 VFASVNAAKGSEKGNGTEWTETTIDSGKTVTINSGRDTVLNGAQVNGNRI-IADVG---- 2633
Query 3060 NNIHVESLQDT----ASSSNSSRGGSIGGGYGSGSKNITASYNQSKGSSDSAWVNTTSKL 3115
+++ + S QDT + ++ + GGS G +GS I AS ++ K DS T
Sbjct 2634 HDLLISSQQDTSKYDSKQTSVAAGGSFTFGSMTGSGYIAASRDKMKSRFDSVAEQT---- 2689
Query 3116 LIGNAQNDANLDAMGVKNITNIGGVIANANKNADGSLTDHKNLNYTGNLELKDLQDHNNN 3175
G D D + V N T + G + + AD KN TG L D+ +
Sbjct 2690 --GMFSGDGGFD-ITVGNHTQLDGAVIASTATAD------KNSLDTGTLGFSDI-----H 2735
Query 3176 NSSGFNVS-TNIGIPQGGS---KAASTAPKGSTTIGLNSSGQETEQLTKATLGQGSVTNA 3231
N + + VS + I + GGS K P G + G +S E T+A + G++T
Sbjct 2736 NEADYKVSHSGISLSGGGSFGDKFQGNMPGGMISAGGHSG--HAEGTTQAAVADGTITIR 2793
Query 3232 TADTNRDINNTQEITRD 3248
D + N ++RD
Sbjct 2794 DRDNQK--QNLANLSRD 2808
Score = 183 bits (464), Expect = 4e-48
Identities = 337/1353 (25%), Positives = 560/1353 (41%), Gaps = 251/1353 (19%)
Query 578 SLSNQSGQLISNQKLNIQTQTANNQKGKIQSVDQ---LDLNVANGLNNIEGQIASGQQLN 634
S+S++S ++SN LN + G+I ++ +V NI AS Q+N
Sbjct 318 SVSSRSDIVLSNGTLNSDKDLSLTAGGRITQQNEKLTAGRDVTLAAKNITQDTAS--QIN 375
Query 635 IQADQVNNQSGLIYSEQQ---GIELKANHAINNTSGIIQAKTQLNLASTQLDNTSGHIQA 691
D V S + ++ Q G L A+ G + AK L + L+N SG +Q
Sbjct 376 AARDIVTVSSDTLTTQGQITAGQNLTASATTLTQDGTLLAKGHAGLDAGTLNN-SGAVQG 434
Query 692 ENIQQQHTTVNNTQGSIVAGQSLISTVDQFDNHQGLIDAKN-IQLTHQ-VLNNSGSIYAD 749
++ TT++N+ GS+++G L F G AK + +T L ++GS+ +D
Sbjct 435 ASLTLGSTTLSNS-GSLLSGGPLTVNTRDF-TQSGRTGAKGKVDITASGKLTSTGSLVSD 492
Query 750 QNIKITGQHILNTGSIAAGQNIQLNTAKLQ-------HEQAALI----AAGLDRQGKLTS 798
+ + Q + G ++ G+ + ++ L H AA+ LD + S
Sbjct 493 DVLVLKAQDVTQNGVLSGGKGLTVSAQALSSGKKSVTHSDAAMTLNVTTVALDGEN---S 549
Query 799 TGD-LDITAEQTTLHGQSFAGQQLKVASKQQIDATNGQL---QAKNIDLASDAGDISTRA 854
GD L + A++ + + AG QL+ I+A + +L QA +A +A + T +
Sbjct 550 AGDTLRVQADKLS----TAAGAQLQSGKNLSINARDARLAGTQAAQQTMAVNASEKLTHS 605
Query 855 ATVIAEQLSLKSHDLIDNQQGTLSAQQLNLTANRLDNTQGHILHTGQDQLDLNFSQSLNN 914
A LSL + +L + G L LN + L N+ L G+ L +N +Q L+N
Sbjct 606 GKSSAPSLSLSAPELTSS--GVLVGSALNTQSQTLTNSG---LLQGEASLTVN-TQRLDN 659
Query 915 QLGEIRSNAAELNIKTALLNNTEGQVVHAGTQQLNIQTAQLNGHLGHILSNGTLQLKAGT 974
Q +AA+L + + N+ + G L + TA L+ G I+++ TL ++A T
Sbjct 660 QQNGTLYSAADLTLDIPDIRNSG---LITGDNGLTLNTASLSNP-GKIIAD-TLNVRATT 714
Query 975 LDVSGGVTSADQITIQANVLNNAQ-------GQLIQRG-------TSNPLNLTIQQQLNN 1020
LD G + A + + + L+ + G L RG T+ NLT+Q
Sbjct 715 LDGDGLLQGAGALALAGDTLSQGRNGRWLTAGDLSLRGKTLHTAGTTQGQNLTVQADNWA 774
Query 1021 QAG-------LIQSATATDIKAGSLNNQ------------RGTLSSAQGQNLDVDVAGKL 1061
+G L SAT G + +Q RG+L SA +LD L
Sbjct 775 NSGSVLATGNLTASATGQLTSTGDIMSQGDTTLNAATTDNRGSLLSAGTLSLD---GNSL 831
Query 1062 DNSQSGQIYAGNQAHLQVGSIDNSHQGQINAQQNLQLTS-------QQQINNQSGQIVAN 1114
DN + Q GN ++ S+ NS G + L L + Q + N G ++ +
Sbjct 832 DNRGTVQ---GNHVTIRQNSVTNS--GTLTGIAALTLAARMDMASPQPALMNNGGSLLTS 886
Query 1115 GDVQIQSQGLNNSHGQMGSLQGGLSLNTGSDTLINQSGLIQAKKDIG--IQAQRIDNQQG 1172
GD+ I + + +S G QG L T +D+L N SG IQA + + + +
Sbjct 887 GDLTITAGSITSS----GHWQGKQVLIT-ADSLAN-SGAIQAADSLTARLTGELVSTAGS 940
Query 1173 QITTQGQAELISQAEIDNLEGAIAADLDVNIRSQGLNNNKGQISSAQGNLTLNAGNGTLT 1232
++T+ G+ L S + N IA +L + S + G I+ LTL N TL
Sbjct 941 KVTSNGEMAL-SALNLSNSGQWIAKNLTLKANSL---TSAGDITGVDA-LTLTV-NQTLN 994
Query 1233 NQAA-TIVSGKTLTLSANQLDNSNHGQINSQNNADISIVKDINNTSGVIAAKQQLILSSQ 1291
N A+ ++S LTL A+ + N GQ+ Q NA + N G + + + +S
Sbjct 995 NHASGKLLSAGVLTLKADSVKND--GQL--QGNATTITAGQLTN-GGHLQGETLTLTASG 1049
Query 1292 GLNNTTGQIGTVQGNLHIDAGSQLLNNQQGRIQSGQDLNLNATGIDNTQGQISSKNQLQL 1351
G+NN +G G + ++ + L+NQ G IQ G ++LNAT ++LQ
Sbjct 1050 GVNNRSG--GVLMSRNALNVSTATLSNQ-GTIQGGGGVSLNAT------------DRLQN 1094
Query 1352 DSREQLLNNRQGTLSAENLTIDSGEL-NNDQGLIQAQQSIQIDTHQHNLSNTNSGAQGGI 1410
D + LS NLT+ + L N GL+QA + ++ NT +G G +
Sbjct 1095 DGK---------ILSGSNLTLTAQVLANTGSGLVQAATLLL------DVVNTVNG--GRV 1137
Query 1411 LSQGNIQLNNIQTLDNQQGYLASAQQLDLQAN-QVFNQNGTLLAAKQLNLQGTGQNQLLN 1469
L+ G+ + TL+N + Q DL N F+ +GTLL L ++G+ LL
Sbjct 1138 LATGSADVKGT-TLNNT----GTLQGADLLVNYHTFSNSGTLLGTSGLGVKGSS---LLQ 1189
Query 1470 NQSGQMLSMGGMNLNIDQINNKGKA-NTADADSHIMAAGELNITTQQLDNQNTLNTDPAN 1528
N +G++ S G + L+ + +G+ T D ++AA L N TL
Sbjct 1190 NGTGRLYSAGNLLLDAQDFSGQGQVVATGDVTLKLIAA---------LTNHGTLAA---- 1236
Query 1529 TSIQGIDANTLNVTSKVLNNQSGVIRSSADQNLNVQQALNNQSGQISSEKQLTLVGDQLE 1588
TL+VTS+ GV++ A L +A N +G +++ K ++ Q
Sbjct 1237 -------GKTLSVTSQNAITNGGVMQGDA-MVLGAGEAFTN-NGMLTAGKGNSVFSAQRL 1287
Query 1589 INNLNGQILAGTALDLIAQSLSGDGKLLSLGNAKLSLQNDYIHSSGAQLQANQDLSLSTK 1648
N G + AG GD L S + +S + ++G+ L+++
Sbjct 1288 FLNAPGSLQAG-----------GDVSLNSRSDITIS---GFTGTAGS-------LTMNVA 1326
Query 1649 GNIINNGTINAGNQLALNAANITNQQ--------------------------AGKIESHD 1682
G ++N+ I AGN L L + NQ +G IE+H
Sbjct 1327 GTLLNSALIYAGNNLKLFTDRLHNQHGDILAGNSLWVQKDASGGANTEIINTSGNIETHQ 1386
Query 1683 TRLTAQNTLNNTGLINGDFTRLQAETLNNQGTGRIYGTTLAIQANTLNNQPDST------ 1736
+ + TG + A T I G A+ L+ PD +
Sbjct 1387 GDIVVR-----TGHLLNQREGFSATTTTRTNPSSIQGMGNALVDIPLSLLPDGSYGYFTR 1441
Query 1737 ------GTAPVIASRGDLHLGVQTLNNLSNPTDYTSQALIFSAG-NLYLGAALDANDYAT 1789
GT G ++ + TL + D +Q + S GA A A+
Sbjct 1442 EVENQHGTP--CNGHGACNITMDTLYYYAPFADSATQRFLSSQNITTVTGADNPAGRIAS 1499
Query 1790 G-----QADVIHNESATIESLGDMNLSAKQINN 1817
G +A+ + N ++ I + GD+ LS ++++N
Sbjct 1500 GRNLSAEAERLENRASFILANGDIALSGRELSN 1532
Score = 165 bits (418), Expect = 1e-42
Identities = 375/1590 (24%), Positives = 622/1590 (39%), Gaps = 303/1590 (19%)
Query 543 NQGGQLNLGRVKIQGERFNNDQGQLTVKQAEIQTNSLSNQSGQLISNQKLNIQTQTANNQ 602
N+ N+G+ +G NN G+L Q G LI N N +
Sbjct 65 NRFTDYNVGK---EGLILNNATGKLN-----------PTQLGGLIQN---NPNLKAGGEA 107
Query 603 KGKIQSVDQLDLNVANGLNNIEGQIASGQQLNIQADQVNNQSGLIYSEQQGIELKANHAI 662
KG I V + ++ G + G+ A+ N + G + L +
Sbjct 108 KGIINEVTGGNRSLLQGYTEVAGKAANVMVANPYGITCD---GCGFINTPHATLTTGRPV 164
Query 663 NNTSGIIQA----KTQLNLASTQLDNTSGHIQAENIQQQHTTVNNTQGS----IVAGQSL 714
N G +QA + + + LD T A +I + T VN + + AG +
Sbjct 165 MNADGSLQALEVTEGSITINGAGLDGTRS--DAVSIIARATEVNAALHAKDLTVTAGANR 222
Query 715 ISTVDQFDNHQGLIDAKNIQLTHQVLNNSGSIYADQNIKITGQHILNTGSIAAGQNIQLN 774
I+ + +G D + + L G +YA + I +T S +G + L
Sbjct 223 ITADGRVSALKGEGDVPKVAVDTGAL---GGMYA-RRIHLT--------STESGVGVNLG 270
Query 775 TAKLQHEQAALIAAGLDRQGKLTSTGDLDITAEQTTLHGQSFAGQQLKVASKQQIDATNG 834
+ L A+G +TG + + TL G AG L V+S+ I +NG
Sbjct 271 NLYARDGDITLDASGRLTVNNSLATGAVTAKGQGVTLTGDHKAGGNLSVSSRSDIVLSNG 330
Query 835 QLQAKNIDLASDAGDIST---------RAATVIAEQLSLKSHDLID-------------N 872
L + DL+ AG T R T+ A+ ++ + I+
Sbjct 331 TLNSDK-DLSLTAGGRITQQNEKLTAGRDVTLAAKNITQDTASQINAARDIVTVSSDTLT 389
Query 873 QQGTLSAQQLNLTANRLDNTQ-GHILHTGQDQLDLNFSQSLNNQLGEIRSNAAELNIKTA 931
QG ++A Q NLTA+ TQ G +L G LD +LNN G ++ A L + +
Sbjct 390 TQGQITAGQ-NLTASATTLTQDGTLLAKGHAGLDAG---TLNNS-GAVQG--ASLTLGST 442
Query 932 LLNNTEGQVVHAGTQQLNIQTAQLNGHLGHILSNGTLQLKA-GTLDVSGGVTSADQITIQ 990
L+N+ G ++ G +N + +G G + G + + A G L +G + S D + ++
Sbjct 443 TLSNS-GSLLSGGPLTVNTRDFTQSGRTG---AKGKVDITASGKLTSTGSLVSDDVLVLK 498
Query 991 ANVLNNAQGQLIQRGT-SNPLNLTIQQQLNNQAGLIQSATATDIKAGSLNNQRGTLS--S 1047
A + Q G S LT+ Q + +S T +D A +LN L +
Sbjct 499 AQ-------DVTQNGVLSGGKGLTVSAQALSSGK--KSVTHSDA-AMTLNVTTVALDGEN 548
Query 1048 AQGQNLDVDVAGKLDNSQSGQIYAGNQAHLQVGSIDNSHQGQINAQQNLQLTSQQQINNQ 1107
+ G L V A KL + Q+ +G +L + + D G AQQ + + + +++ +
Sbjct 549 SAGDTLRVQ-ADKLSTAAGAQLQSGK--NLSINARDARLAGTQAAQQTMAVNASEKLTH- 604
Query 1108 SGQIVANGDVQIQSQGLNNSHGQMGSLQGGLSLNTGSDTLINQSGLIQAKKDIGIQAQRI 1167
SG+ A + + + L +S +GS +LNT S TL N SGL+Q + + + QR+
Sbjct 605 SGKSSAPS-LSLSAPELTSSGVLVGS-----ALNTQSQTLTN-SGLLQGEASLTVNTQRL 657
Query 1168 DNQQGQITTQGQAELISQAEIDNLEGAIAADLDVNIRSQGLNNNKGQISSAQGNL--TLN 1225
DNQQ T A+L G I D + + + L+N G+I + N+ T
Sbjct 658 DNQQNG-TLYSAADLTLDIPDIRNSGLITGDNGLTLNTASLSN-PGKIIADTLNVRATTL 715
Query 1226 AGNGTLTNQAATIVSGKTLTLSANQL-----DNSNHGQI----NSQNNADISIVKDINNT 1276
G+G L A ++G TL+ N D S G+ + ++++ D
Sbjct 716 DGDGLLQGAGALALAGDTLSQGRNGRWLTAGDLSLRGKTLHTAGTTQGQNLTVQADNWAN 775
Query 1277 SGVIAAKQQLILSSQGLNNTTGQIGTVQGNLHIDAGSQLLNNQQGRIQSGQDLNLNATGI 1336
SG + A L S+ G +TG I + QG+ ++A + + +G + S L+L+ +
Sbjct 776 SGSVLATGNLTASATGQLTSTGDIMS-QGDTTLNAAT---TDNRGSLLSAGTLSLDGNSL 831
Query 1337 DN-----------------TQGQISSKNQLQLDSREQ-------LLNNRQGTLSAENLTI 1372
DN G ++ L L +R L+NN L++ +LTI
Sbjct 832 DNRGTVQGNHVTIRQNSVTNSGTLTGIAALTLAARMDMASPQPALMNNGGSLLTSGDLTI 891
Query 1373 DSGELNN-----------------DQGLIQAQQSIQIDTHQHNLSNTNSGAQGGILSQGN 1415
+G + + + G IQA S+ +S S + S G
Sbjct 892 TAGSITSSGHWQGKQVLITADSLANSGAIQAADSLTARLTGELVSTAGSK----VTSNGE 947
Query 1416 IQLNNIQTLDNQQGYLASAQQLDLQANQVFNQNGTLLAAKQLNLQGTGQNQLLNNQ-SGQ 1474
+ L+ + ++ Q A+ L L+AN + + G + L L NQ LNN SG+
Sbjct 948 MALSALNLSNSGQWI---AKNLTLKANSLTSA-GDITGVDALTLT---VNQTLNNHASGK 1000
Query 1475 MLSMGGMNLNIDQINNKGKANTADADSHIMAAGELNITTQQLDNQNTLNTDPANTSIQG- 1533
+LS G + L D + N G+ + IT QL N L + + G
Sbjct 1001 LLSAGVLTLKADSVKNDGQ----------LQGNATTITAGQLTNGGHLQGETLTLTASGG 1050
Query 1534 ---------IDANTLNVTSKVLNNQSGVIRSSADQNLNVQQALNNQSGQISSEKQLTLVG 1584
+ N LNV++ L+NQ G I+ +LN L N G+I S LTL
Sbjct 1051 VNNRSGGVLMSRNALNVSTATLSNQ-GTIQGGGGVSLNATDRLQND-GKILSGSNLTLTA 1108
Query 1585 DQLEINNLNGQILAGTALDLIAQSLSGDGKLLSLGNA--KLSLQNDYIHSSGAQLQANQD 1642
Q+ N +G + A T L + +++G G++L+ G+A K + N+ GA L N
Sbjct 1109 -QVLANTGSGLVQAATLLLDVVNTVNG-GRVLATGSADVKGTTLNNTGTLQGADLLVNYH 1166
Query 1643 L-----------SLSTKGN-IINNGT---INAGNQL-----------ALNAANITNQQAG 1676
L KG+ ++ NGT +AGN L + ++T +
Sbjct 1167 TFSNSGTLLGTSGLGVKGSSLLQNGTGRLYSAGNLLLDAQDFSGQGQVVATGDVTLKLIA 1226
Query 1677 KIESHDT-------RLTAQNTLNNTGLINGDFTRLQA-ETLNNQG---TGRIYGTTLAIQ 1725
+ +H T +T+QN + N G++ GD L A E N G G+ G ++
Sbjct 1227 ALTNHGTLAAGKTLSVTSQNAITNGGVMQGDAMVLGAGEAFTNNGMLTAGK--GNSVFSA 1284
Query 1726 ANTLNNQPDS--TGTAPVIASRGDLHLG--VQTLNNLSNPTDYT--SQALIFSAGNLYL- 1778
N P S G + SR D+ + T +L+ T + ALI++ NL L
Sbjct 1285 QRLFLNAPGSLQAGGDVSLNSRSDITISGFTGTAGSLTMNVAGTLLNSALIYAGNNLKLF 1344
Query 1779 -------------GAALDANDYATGQADV-IHNESATIES-LGDMNLSAKQINNINKYFK 1823
G +L A+G A+ I N S IE+ GD+ + + N + F
Sbjct 1345 TDRLHNQHGDILAGNSLWVQKDASGGANTEIINTSGNIETHQGDIVVRTGHLLNQREGFS 1404
Query 1824 TEQVEVSRKDGLEKYCDAWCTF------DGNY---------------------------- 1849
+ ++ +A DG+Y
Sbjct 1405 ATTTTRTNPSSIQGMGNALVDIPLSLLPDGSYGYFTREVENQHGTPCNGHGACNITMDTL 1464
Query 1850 YDGNPYED--WMRYYYSEITYETRTTESAPGQIKAGGHLDLNGAQVVNDKSQILAGGELK 1907
Y P+ D R+ S+ ++ G+I +G +L ++ N S ILA G++
Sbjct 1465 YYYAPFADSATQRFLSSQNITTVTGADNPAGRIASGRNLSAEAERLENRASFILANGDIA 1524
Query 1908 NEGGTIDSGTQIAGIRKIVNTGTQVKYWKY 1937
G + + + TGT+ +Y Y
Sbjct 1525 LSGRELSNQSW--------QTGTENEYLVY 1546
Score = 78.2 bits (191), Expect = 3e-16
Identities = 358/1894 (19%), Positives = 671/1894 (35%), Gaps = 336/1894 (18%)
Query 99 SQQPTILNSSNGVTQVNIQTPSAGGVSRNTYSQF--------DVGQEGAILNNARNNTQT 150
S QP ++N+ + T +AG ++ + + Q + GAI A ++
Sbjct 871 SPQPALMNNGGSLLTSGDLTITAGSITSSGHWQGKQVLITADSLANSGAI--QAADSLTA 928
Query 151 QLGGWI---QGNPWLAKGEAKVILNEVNSSNPSQ------------LKGYIEVAGKQAQV 195
+L G + G+ + GE + L+ +N SN Q L ++ G A
Sbjct 929 RLTGELVSTAGSKVTSNGE--MALSALNLSNSGQWIAKNLTLKANSLTSAGDITGVDALT 986
Query 196 VIANPSGLVCDGCGVINADRFTLTTGQAVMNQGYLE--SFRVREGQITIQGKGLNGSLTP 253
+ N + +++A TL +V N G L+ + + GQ+T G +LT
Sbjct 987 LTVNQTLNNHASGKLLSAGVLTLKA-DSVKNDGQLQGNATTITAGQLTNGGHLQGETLT- 1044
Query 254 FTDVYARALQVNAGLYAKELNVVLGQNDINVNDPTTSNVSPIQ----------------- 296
L + G+ + V++ +N +NV+ T SN IQ
Sbjct 1045 --------LTASGGVNNRSGGVLMSRNALNVSTATLSNQGTIQGGGGVSLNATDRLQNDG 1096
Query 297 ---------------SNTSANNKPQFALDVGQLGGMYAGKIFLVGTE--QGVGVRNAGSM 339
+NT + L + + + G++ G+ +G + N G++
Sbjct 1097 KILSGSNLTLTAQVLANTGSGLVQAATLLLDVVNTVNGGRVLATGSADVKGTTLNNTGTL 1156
Query 340 NSTQSTL---TLNANGDLTNTGNL--------------IANQGQLQLNAENIKNTGNISS 382
+ T + +G L T L + + G L L+A++ G +
Sbjct 1157 QGADLLVNYHTFSNSGTLLGTSGLGVKGSSLLQNGTGRLYSAGNLLLDAQDFSGQGQVV- 1215
Query 383 ATSQVSLHS-QNLDNSGLISSADELNIQQQGHVGNRGTLNAARIVVDAGSLANSGSIEQT 441
AT V+L L N G +++ L++ Q + N G + +V+ AG + +
Sbjct 1216 ATGDVTLKLIAALTNHGTLAAGKTLSVTSQNAITNGGVMQGDAMVLGAGEAFTNNGMLTA 1275
Query 442 G-------AQALDLKAGSMSNIGGKIGIAKTSSTGGNGSESGGGSQPVEPNNAAQDGGSL 494
G AQ L L A GG + + S +G GS + + +
Sbjct 1276 GKGNSVFSAQRLFLNAPGSLQAGGDVSLNSRSDITISGFTGTAGSLTMNVAGTLLNSALI 1335
Query 495 EVVNTDSTPTTPKTYETGYIHVRDQLNNDQGAIVAQGGIDLE------SNNGLDNQGGQL 548
N T D+L+N G I+A + ++ +N + N G +
Sbjct 1336 YAGNNLKLFT-------------DRLHNQHGDILAGNSLWVQKDASGGANTEIINTSGNI 1382
Query 549 NLGRVKI---QGERFNNDQGQLTVKQAEIQTNSLSNQSGQLIS-------NQKLNIQTQT 598
+ I G N +G +S+ L+ + T+
Sbjct 1383 ETHQGDIVVRTGHLLNQREGFSATTTTRTNPSSIQGMGNALVDIPLSLLPDGSYGYFTRE 1442
Query 599 ANNQKGK---------------------IQSVDQLDLNVAN-----GLNNIEGQIASGQQ 632
NQ G S Q L+ N G +N G+IASG+
Sbjct 1443 VENQHGTPCNGHGACNITMDTLYYYAPFADSATQRFLSSQNITTVTGADNPAGRIASGRN 1502
Query 633 LNIQADQVNNQSGLIYSEQQGIELKANHAINNT---------------------SGIIQA 671
L+ +A+++ N++ I + I L N + S +
Sbjct 1503 LSAEAERLENRASFILANGD-IALSGRELSNQSWQTGTENEYLVYRYDPKTFYGSYATGS 1561
Query 672 KTQLNLASTQLDNTSGHIQAENIQQQHTTVNNTQGSIVAGQSLISTVDQFDNHQGLIDAK 731
+L L S + +N + + ++ +T I AG +
Sbjct 1562 LDKLPLLSPEFENNTIRFSLDGREKDYTPGKTYYSVIQAGGDV----------------- 1604
Query 732 NIQLTHQVLNNSGSIYADQNIKITGQHILNTGSIAAGQNIQLNTAKLQHEQAALIAAGLD 791
+ T + N + + +A + +LNT S G + TA Q+E + +
Sbjct 1605 KTRFTSSINNGTTTAHAGSVSPVVSAPVLNTLSQQTGGDSLTQTALQQYEPVVVGSP--- 1661
Query 792 RQGKLTSTGDLDITAEQTTLHGQSFAGQQLKVASKQ------QIDATNGQLQAKNIDLAS 845
Q G L A + L GQ+ + S D + L N L
Sbjct 1662 -QWHDELAGALKNIAGGSPLTGQTGISDDWPLPSGNNGYLVPSTDPDSPYLITVNPKL-D 1719
Query 846 DAGDISTRAATVIAEQLSLK--------SHDLIDNQQ---GTLSAQQLNLTANRLDNTQG 894
G + + + E L K + D +Q + +L L + G
Sbjct 1720 GLGQVDSHLFAGLYELLGAKPGQAPRETAPSYTDEKQFLGSSYFLDRLGLKPEKDYRFLG 1779
Query 895 HILHTGQDQLDLNFSQSLNNQLGEIRSNAAELNIKTALLNNTEGQVVHAGTQQLNIQTAQ 954
+ + + S++ + L + S+ ++ L++N Q G + TA+
Sbjct 1780 DAVFDTRYVSNAVLSRTGSRYLNGLGSDTEQMRY---LMDNAARQQKGLGLEFGVALTAE 1836
Query 955 LNGHL-GHILSNGTLQLKAGTLDVSGGVTSADQIT------IQANVLNNAQGQLIQRGTS 1007
L G IL + + T+ V S + IT I N + A G + G S
Sbjct 1837 QIAQLDGSILWWESATINGQTVMVPKLYLSPEDITLHNGSVISGNNVQLAGGNITNSGGS 1896
Query 1008 ----NPLNLTIQQQLNN-QAGLIQSATATDIKA-GSLNNQRGTLSSAQGQNLDVD-VAGK 1060
N L+L ++N AGLI + + D+ A G ++N +S G+ + ++ V+G
Sbjct 1897 INAQNGLSLDSTGYIDNLNAGLISAGGSLDLSAIGDISNISSVIS---GKTVQLESVSGN 1953
Query 1061 LDN------------SQSGQIYAGNQAHLQVGSIDNSHQGQINAQQNLQLTSQQQINNQS 1108
+ N S+ G ++ V +I + ++A +N+ +T + +
Sbjct 1954 ISNITRRQQWNAGSDSRYGGVHLSGTDTGPVATIKGTDSLSLDAGKNIDITGATVSSGGT 2013
Query 1109 GQIVANGDVQIQSQGLNNSHGQMGSLQGGLSLNTGSDTLINQSGLIQAKKDIGIQAQRID 1168
+ A D+ I + ++ S Q G N+ S T +Q I A ++ + A
Sbjct 2014 LGMSAGNDINIAANLISGSKSQSGFWH--TDDNSASST-TSQGSSISAGGNLAMAAGHNL 2070
Query 1169 NQQGQITTQGQAELISQAEIDNLEGAIAADLDVNIRSQGLNNNKGQISSAQGNLTLNAGN 1228
+ + G + L+S DL +N + N+ G+ S + + +
Sbjct 2071 DVTASSVSAGHSALLSAGN----------DLSLNAVRESKNSRNGRSESHESHAAV---- 2116
Query 1229 GTLTNQAATIVSGKTLTLSANQLDNSNHGQINSQNNADISIVKDINNTS-GVIAAKQQLI 1287
+T+ +G L L A + S + ++NN I +D+N + A
Sbjct 2117 -------STVTAGDNLLLVAGRDVASQAAGVAAENNVVIRGGRDVNLVAESAGAGDSYTS 2169
Query 1288 LSSQGLNNTTGQIGT---VQGNLHIDAG-------SQLLNNQQGRIQSGQDLNL-NATGI 1336
+ +N T Q GT G+ ++AG S + + +G+D+ L AT
Sbjct 2170 KKKKEINETVRQQGTEIASGGDTTVNAGRDITAVASSVTATGNISVNAGRDVALTTATES 2229
Query 1337 D--------NTQGQISSKNQLQLD----SRE--QLLNNRQGTLSA-ENLTIDSGELNNDQ 1381
D + G +S K + SRE LL+ + T++A +NLT++ ++ DQ
Sbjct 2230 DYHYLETKKKSGGFLSKKTTHTISEDSASREAGSLLSGNRVTVNAGDNLTVEGSDVVADQ 2289
Query 1382 GLIQAQQSIQIDTHQHNLSNTNSGA--------QGGILSQGNIQL---NNIQTLDNQQGY 1430
+ S+ H L+ T++ + G++ G I ++ T D ++
Sbjct 2290 DV-----SLAAGNHVDVLAATSTDTSWRFKETKKSGLMGTGGIGFTIGSSKTTHDRREAG 2344
Query 1431 LASAQQLDLQANQVFNQNGTLLAAKQLNLQGT---GQNQLLNNQSGQMLSMGGMNLNIDQ 1487
+Q + N ++ A KQ ++ G+ + ++ G +D+
Sbjct 2345 TTQSQSASTIGSTA--GNVSITAGKQAHISGSDVIANRDISITGDSVVVDPGHDRRTVDE 2402
Query 1488 INNKGKANTADADSHIMAAGELNITTQQLDNQNTLNTDPANTSIQGIDANTLNVTSKVLN 1547
+ K+ A S + + N T + + + +++ ++ + A ++
Sbjct 2403 KFEQKKSGLTVALSGTVGSAINNAVTSAQETK-----ESSDSRLKALQATKTALSGVQAG 2457
Query 1548 NQSGVIRSSADQN-LNVQQALNNQSGQISSEKQL-TLVGDQLEI-NNLNGQILAGTALDL 1604
+ + ++ D N V +L Q + + T+ G L NNL+ D
Sbjct 2458 QAAAMATATGDPNATGVSLSLTTQKSKSQQHSESDTVSGSTLNAGNNLSVVATGKNRGDN 2517
Query 1605 IAQSLSGDGKLLSLGNAKLSLQNDYIHSSGAQLQANQDLSLSTKGNI-INNGTINAGNQL 1663
+ +L + GN L ND + S A Q + S+ G + ++ G GN
Sbjct 2518 RGDIVIAGSQLKAGGNTSLDAANDVLLSGAANTQKTTGRNSSSGGGVGVSIGA--GGNGA 2575
Query 1664 ALNAANITNQQAGKIESHDTRLTAQNTLNN--TGLIN-GDFTRLQAETLNNQGTGRIYGT 1720
++ N G + + T T + T+++ T IN G T L +N G
Sbjct 2576 GISVFASVNAAKGSEKGNGTEWT-ETTIDSGKTVTINSGRDTVLNGAQVNGNRIIADVGH 2634
Query 1721 TLAIQANTLNNQPDSTGTAPVIASRGDLHLGVQT 1754
L I + ++ DS T+ +A+ G G T
Sbjct 2635 DLLISSQQDTSKYDSKQTS--VAAGGSFTFGSMT 2666
Score = 70.9 bits (172), Expect = 5e-14
Identities = 195/965 (20%), Positives = 359/965 (37%), Gaps = 139/965 (14%)
Query 353 DLTNTGNLIANQGQLQLNAENIKNTGNISSATSQVSLHS----QNLDNSGLISSADELNI 408
D+T + + +QL NI N+G +A + +SL S NL N+GLIS+ L++
Sbjct 1869 DITLHNGSVISGNNVQLAGGNITNSGGSINAQNGLSLDSTGYIDNL-NAGLISAGGSLDL 1927
Query 409 QQQGHVGNRGTLNAARIVVDAGSLANSGSIEQTGAQALDLKAGSMSNIGGKIGIAKTSST 468
G + N ++ + + V N +I + AGS S GG
Sbjct 1928 SAIGDISNISSVISGKTVQLESVSGNISNI----TRRQQWNAGSDSRYGG---------V 1974
Query 469 GGNGSESGGGSQPVEPNNAAQDGGSLEVVNTDSTPTTPKTYETGYIHVRDQLN---NDQG 525
+G+++G + ++ + D G N D T T + T + + +N N
Sbjct 1975 HLSGTDTGPVATIKGTDSLSLDAGK----NIDITGATVSSGGTLGMSAGNDINIAANLIS 2030
Query 526 AIVAQGGI---DLESNNGLDNQGGQLNLGRVKIQGERFNNDQGQLTVKQAEIQTNSLSNQ 582
+Q G D S + +QG ++ G N D +V S N
Sbjct 2031 GSKSQSGFWHTDDNSASSTTSQGSSISAGGNLAMAAGHNLDVTASSVSAGHSALLSAGN- 2089
Query 583 SGQLISNQKLNIQTQTANNQKGKIQSVD-QLDLNVANGLNNIEGQIASGQQLNIQADQVN 641
+ LN ++ N++ G+ +S + ++ +N+ + +G+ + QA V
Sbjct 2090 ------DLSLNAVRESKNSRNGRSESHESHAAVSTVTAGDNL--LLVAGRDVASQAAGVA 2141
Query 642 NQSGLIYSEQQGIELKANHAINNTSGIIQAKTQLNLASTQLDNTSGHIQAENIQQQHTTV 701
++ ++ + + L A A S + K ++N E ++QQ T +
Sbjct 2142 AENNVVIRGGRDVNLVAESAGAGDSYTSKKKKEIN---------------ETVRQQGTEI 2186
Query 702 -NNTQGSIVAGQSLISTVDQFDNHQGLIDAKNIQLTHQVLNNSGSIYADQNIKITGQHIL 760
+ ++ AG+ + + A ++ T + N+G A + H L
Sbjct 2187 ASGGDTTVNAGRDITAV------------ASSVTATGNISVNAGRDVALTTATESDYHYL 2234
Query 761 NTGSIAAGQNIQLNTAKLQHEQAALIAAGLDRQGKLTSTGDLDITAEQTTLHGQS----F 816
T + G + T + + A+ A L ++T ++T E + +
Sbjct 2235 ETKKKSGGFLSKKTTHTISEDSASREAGSLLSGNRVTVNAGDNLTVEGSDVVADQDVSLA 2294
Query 817 AGQQLKVASKQQIDATNGQLQAKNIDLASDAGDISTRAATVIAEQLSLKSHDLIDNQQGT 876
AG + V + D + + K L G T + S +HD + GT
Sbjct 2295 AGNHVDVLAATSTDTSWRFKETKKSGLMGTGGIGFTIGS-------SKTTHD--RREAGT 2345
Query 877 LSAQQLNLTANRLDNTQGHILHTGQDQLDLNFSQSLNNQLGEIRSNAAELNIKTALLNNT 936
+Q +A+ + +T G++ T Q ++ S + N+ I ++ ++ +
Sbjct 2346 TQSQ----SASTIGSTAGNVSITAGKQAHISGSDVIANRDISITGDSVVVD-----PGHD 2396
Query 937 EGQVVHAGTQQLNIQTAQLNGHLGHILSNGTLQLKAGTLDVSGGVTSADQITIQA-NVLN 995
V Q+ + T L+G +G ++N + T + S A Q T A + +
Sbjct 2397 RRTVDEKFEQKKSGLTVALSGTVGSAINNAVTSAQE-TKESSDSRLKALQATKTALSGVQ 2455
Query 996 NAQGQLIQRGTSNPLNLTIQQQLNNQAGLIQSATATDIKAGSLNNQRGTLSSAQGQNLDV 1055
Q + T +P + L Q Q + +D +GS N G NL V
Sbjct 2456 AGQAAAMATATGDPNATGVSLSLTTQKSKSQQHSESDTVSGSTLN--------AGNNLSV 2507
Query 1056 DVAGKLDNSQSGQI-YAGNQAHLQVG---SIDNSHQGQINAQQNLQLTSQQQINNQSG-- 1109
GK G I AG+Q L+ G S+D ++ ++ N Q T+ + ++ G
Sbjct 2508 VATGKNRGDNRGDIVIAGSQ--LKAGGNTSLDAANDVLLSGAANTQKTTGRNSSSGGGVG 2565
Query 1110 ------------QIVANGDVQIQSQGLNNSHGQMGSLQGG--LSLNTGSDTLINQSG--- 1152
+ A+ + S+ N + ++ G +++N+G DT++N +
Sbjct 2566 VSIGAGGNGAGISVFASVNAAKGSEKGNGTEWTETTIDSGKTVTINSGRDTVLNGAQVNG 2625
Query 1153 ---LIQAKKDIGIQAQ----RIDNQQGQITTQGQAELISQAEIDNLEGAIAADLD-VNIR 1204
+ D+ I +Q + D++Q + G S G IAA D + R
Sbjct 2626 NRIIADVGHDLLISSQQDTSKYDSKQTSVAAGGSFTFGSMTG----SGYIAASRDKMKSR 2681
Query 1205 SQGLNNNKGQISSAQGNLTLNAGNGTLTNQAATIVSGKTLTLSANQLDNSNHGQINSQNN 1264
+ G S G + GN T + A V T T N LD G + N
Sbjct 2682 FDSVAEQTGMF-SGDGGFDITVGNHTQLDGA---VIASTATADKNSLDTGTLGFSDIHNE 2737
Query 1265 ADISI 1269
AD +
Sbjct 2738 ADYKV 2742
Score = 70.1 bits (170), Expect = 8e-14
Identities = 240/1222 (20%), Positives = 450/1222 (37%), Gaps = 231/1222 (19%)
Query 742 NSGSIYADQNIKITGQHILNT-GSIAAGQNIQL-NTAKLQHEQAALIAAGLDRQGKLTST 799
++GS+ + N+++ G +I N+ GSI A + L +T + + A LI+AG G L +
Sbjct 1873 HNGSVISGNNVQLAGGNITNSGGSINAQNGLSLDSTGYIDNLNAGLISAG----GSLDLS 1928
Query 800 GDLDITAEQTTLHG-----QSFAGQQLKVASKQQIDATNGQLQAKNIDLASDAGDISTRA 854
DI+ + + G +S +G + +QQ +A + +D G ++T
Sbjct 1929 AIGDISNISSVISGKTVQLESVSGNISNITRRQQWNAGSDSRYGGVHLSGTDTGPVATIK 1988
Query 855 ATVIAEQLSLKSHDLIDNQQGTLSA---------QQLNLTANRL--DNTQGHILHTGQDQ 903
T + LSL + ID T+S+ +N+ AN + +Q HT +
Sbjct 1989 GT---DSLSLDAGKNIDITGATVSSGGTLGMSAGNDINIAANLISGSKSQSGFWHTDDNS 2045
Query 904 LDLNFSQSLNNQLGEIRSNAAELNI----------KTALLNNTEGQVVHAGTQQLNIQTA 953
SQ + G + AA N+ +ALL+ ++A + N +
Sbjct 2046 ASSTTSQGSSISAGGNLAMAAGHNLDVTASSVSAGHSALLSAGNDLSLNAVRESKNSRNG 2105
Query 954 QLNGHLGH-----ILSNGTLQLKAG--TLDVSGGVTSADQITIQANVLNNAQGQLIQRGT 1006
+ H H + + L L AG + GV + + + I+ N + G
Sbjct 2106 RSESHESHAAVSTVTAGDNLLLVAGRDVASQAAGVAAENNVVIRGGRDVNLVAESAGAGD 2165
Query 1007 S--NPLNLTIQQQLNNQAGLIQSATATDIKAG-------SLNNQRGTLSSAQGQNLDVDV 1057
S + I + + Q I S T + AG S G +S G+++ +
Sbjct 2166 SYTSKKKKEINETVRQQGTEIASGGDTTVNAGRDITAVASSVTATGNISVNAGRDVALTT 2225
Query 1058 AGKLD------NSQSGQIYAGNQAHL--------QVGSIDNSHQGQINAQQNLQLTSQQQ 1103
A + D +SG + H + GS+ + ++ +NA NL +
Sbjct 2226 ATESDYHYLETKKKSGGFLSKKTTHTISEDSASREAGSLLSGNRVTVNAGDNLTVEGSDV 2285
Query 1104 INNQSGQIVANGDVQI---------------QSQGL------------------------ 1124
+ +Q + A V + + GL
Sbjct 2286 VADQDVSLAAGNHVDVLAATSTDTSWRFKETKKSGLMGTGGIGFTIGSSKTTHDRREAGT 2345
Query 1125 --NNSHGQMGSLQGGLSLNTGSDTLINQSGLIQAKKDIGIQAQR--IDNQQGQITTQGQA 1180
+ S +GS G +S+ G I+ S +I A +DI I +D + T +
Sbjct 2346 TQSQSASTIGSTAGNVSITAGKQAHISGSDVI-ANRDISITGDSVVVDPGHDRRTVDEKF 2404
Query 1181 ELISQAEIDNLEGAIAADLDVNIRSQGLNNNKGQISSAQGNLTLNAGNGTLTNQAATI-- 1238
E L G + + ++ + S T A +G QAA +
Sbjct 2405 EQKKSGLTVALSGTVGSAINNAVTSAQETKESSDSRLKALQATKTALSGVQAGQAAAMAT 2464
Query 1239 ------VSGKTLTLSANQLDNSNHGQ--------INSQNNADI----------------- 1267
+G +L+L+ + + H + +N+ NN +
Sbjct 2465 ATGDPNATGVSLSLTTQKSKSQQHSESDTVSGSTLNAGNNLSVVATGKNRGDNRGDIVIA 2524
Query 1268 -SIVKDINNTSGVIAAKQQLILSSQGLNNTTGQIGTVQGNLHIDAGSQLLNNQQGRIQSG 1326
S +K NTS + AA L+ + TTG+ + G + + G+ I
Sbjct 2525 GSQLKAGGNTS-LDAANDVLLSGAANTQKTTGRNSSSGGGVGVSIGA---GGNGAGISVF 2580
Query 1327 QDLNL-----NATGIDNTQGQISSKNQLQLDS-REQLLNNRQGTLSAENLTIDSGELNND 1380
+N G + T+ I S + ++S R+ +LN Q ++ + D G +D
Sbjct 2581 ASVNAAKGSEKGNGTEWTETTIDSGKTVTINSGRDTVLNGAQ--VNGNRIIADVG---HD 2635
Query 1381 QGLIQAQQSIQIDTHQHNLSNTNSGAQGGILSQGNI------QLNNIQTLDNQQGYLASA 1434
+ Q + + D+ Q +++ S G + G I + ++ Q G +
Sbjct 2636 LLISSQQDTSKYDSKQTSVAAGGSFTFGSMTGSGYIAASRDKMKSRFDSVAEQTGMFSGD 2695
Query 1435 QQLDLQANQVFNQNGTLLAA------KQLNLQGTGQNQLLN------NQSGQMLSMGGM- 1481
D+ +G ++A+ L+ G + + N + SG LS GG
Sbjct 2696 GGFDITVGNHTQLDGAVIASTATADKNSLDTGTLGFSDIHNEADYKVSHSGISLSGGGSF 2755
Query 1482 ------NLNIDQINNKGKANTADADSHIMAAGELNITTQQLDNQN----TLNTDP--ANT 1529
N+ I+ G + A+ + A + IT + DNQ L+ DP AN
Sbjct 2756 GDKFQGNMPGGMISAGGHSGHAEGTTQ-AAVADGTITIRDRDNQKQNLANLSRDPAHAND 2814
Query 1530 SIQGI--------DANTLNVTSKVLNNQSGVIRSSADQNLNVQQALNNQSGQI---SSEK 1578
SI I T+ + S + + + + R+ + LN +A ++ G + ++E+
Sbjct 2815 SISPIFDKEKEQRRLQTVGLISDIGSQVADIARTQGE--LNALKAAQDKYGPVPADATEE 2872
Query 1579 Q----LTLVGDQLEINNLNGQILAGTALDLIAQSLSGDGKLLSLGNAKLSLQNDYIHSSG 1634
Q L + D E + G+ + Q+ + + L+ GN +L
Sbjct 2873 QRQAYLAKLRDTPEYKKEQEKYGTGSEIQRGIQAATAALQGLAGGNLAGALAGASAPELA 2932
Query 1635 AQLQANQ-DLSLSTKGNIINNGTINA--GNQLALNAAN-ITNQQAGKIESHDTRLTAQNT 1690
L++ + D +++ + I GT+ A GN +A AA T + A + A
Sbjct 2933 HLLKSTEKDPAVNAIAHAILGGTVAAMQGNNVAAGAAGAATGELAAR---------AIAG 2983
Query 1691 LNNTGLINGDFTRLQAETLNNQGT------GRIYG---TTLAIQANTLNNQPDSTGTAPV 1741
+ G+ D + Q +T++ T G + G + A+ A + N ++ +
Sbjct 2984 MLYPGVKQSDLSEEQKQTISTLATVSAGLAGGLTGNSTASAAVGAQSGKNAVENNYLS-- 3041
Query 1742 IASRGDLHLGVQTLNNLSNPTD 1763
++ + +L + QTL N +P +
Sbjct 3042 VSEKTELEIAKQTLKNSKDPAE 3063
Score = 67.8 bits (164), Expect = 4e-13
Identities = 222/1032 (22%), Positives = 386/1032 (37%), Gaps = 142/1032 (14%)
Query 2210 VKVRVGDLKG-DGTLLSGNSVNLKLDGDLINGATIAGREALQITADNVQNLNGRIQG--- 2265
V V +G+L DG + S L ++ L GA A + + +T D+ N +
Sbjct 265 VGVNLGNLYARDGDITLDASGRLTVNNSLATGAVTAKGQGVTLTGDHKAGGNLSVSSRSD 324
Query 2266 ---NQVAIETQKDLNNIGGQIIAKDAMALKVGGNLNI--ESTTRTSESKVGNFSSSITNV 2320
+ + + KDL+ G I + L G ++ + ++ T+ + S++ N + I V
Sbjct 325 IVLSNGTLNSDKDLSLTAGGRITQQNEKLTAGRDVTLAAKNITQDTASQI-NAARDIVTV 383
Query 2321 DRVAGLYVGNGSTKQLDPNQATLM-----LNVAGNSSLKGVQINNSNS---------ATV 2366
G + Q AT + L G++ L +NNS + +T
Sbjct 384 SSDTLTTQGQITAGQNLTASATTLTQDGTLLAKGHAGLDAGTLNNSGAVQGASLTLGSTT 443
Query 2367 LNTTGNVDLGTVSVGKQETLKIDDKNGYQLKQQQDVGSQIKSAGSLLINGQNITSKAVDL 2426
L+ +G++ G + G + K ++ S GSL ++ + KA D+
Sbjct 444 LSNSGSLLSGGPLTVNTRDFTQSGRTGAKGKVDITASGKLTSTGSL-VSDDVLVLKAQDV 502
Query 2427 NSQQGDIQLSAQKDIVLDNGLNQSTVSSQSQSKGSFGGKKSSTYDASSST------SIAN 2480
+Q G VL G TVS+Q+ S G KKS T+ ++ T ++
Sbjct 503 -TQNG----------VLSGGKGL-TVSAQALSSG----KKSVTHSDAAMTLNVTTVALDG 546
Query 2481 QLNAGQNIIINSAQGNISATHLQAEAGNNIQIHAQQGNVTLLSAIDDKRESSTSSKKGVA 2540
+ +AG + + + + + +A Q ++G N+ I+A+ + A + S K
Sbjct 547 ENSAGDTLRVQADKLS-TAAGAQLQSGKNLSINARDARLAGTQAAQQTMAVNASEK---L 602
Query 2541 TYNNRQSGYIDQEVAQTTLKAGDTVDINAAKNIELQANDVQAGNSIYVGNTLMQRQADGS 2600
T++ + S ++ ++A EL ++ V G+++ NT Q +
Sbjct 603 THSGKSSA--------------PSLSLSAP---ELTSSGVLVGSAL---NTQSQTLTNSG 642
Query 2601 LKAADGSLMPENVTLSTLATKDEQWDEQQKGYRGIVKDI-VKATAVGLAGIEALAPGLKA 2659
L + SL T++T ++ D QQ G D+ + + +G+ GL
Sbjct 643 LLQGEASL-----TVNT-----QRLDNQQNGTLYSAADLTLDIPDIRNSGLITGDNGLTL 692
Query 2660 PKITVSESTGKRTEQISQTGSSLKADNVYVGSSGQTTLTSTDITAKNTILLGQKVTLNAA 2719
++S + ++ ++L D + G+ T +N G+ +T
Sbjct 693 NTASLSNPGKIIADTLNVRATTLDGDGLLQGAGALALAGDTLSQGRN----GRWLTAGDL 748
Query 2720 EEQKITVESTSKETVQGLGAKLNKDSIRLGGFVLEDASQSSKTTETTHKLGSINTENLKI 2779
+ T+ + T QG + D+ G VL + ++ T G I ++
Sbjct 749 SLRGKTLHTAG--TTQGQNLTVQADNWANSGSVLATGNLTASATGQLTSTGDIMSQ---- 802
Query 2780 QGVEGVDILGQNITATGDTLIDHGRGDLNVGGYENKTTVEDKTHVETISTEVGVRNAYLD 2839
G L T +L+ G L+ +N+ TV+ HV TI + L
Sbjct 803 ----GDTTLNAATTDNRGSLLSAGTLSLDGNSLDNRGTVQGN-HV-TIRQNSVTNSGTLT 856
Query 2840 --AALALGAVKDAAEA----VKQAKDQYSQAQRDYASGKITKEALDDSKANVAMATANLA 2893
AAL L A D A + + +G IT K V + +LA
Sbjct 857 GIAALTLAARMDMASPQPALMNNGGSLLTSGDLTITAGSITSSGHWQGK-QVLITADSLA 915
Query 2894 NAQIAVGSAAATAAASSATYGFTIGANGERIETTNTTNTTQGKWQGSTLELNNLTLKSEN 2953
N+ A AA S T T GE + T + T+ G+ S L L+N + +
Sbjct 916 NS-------GAIQAADSLTARLT----GELVSTAGSKVTSNGEMALSALNLSN-SGQWIA 963
Query 2954 QDVNVQGSRLTATGTTSFDGTKDLNVTAGTEHSQQETSSKTNSQSVSYTYGGGGSASIGK 3013
+++ ++ + LT+ G G L +T + S K S V A K
Sbjct 964 KNLTLKANSLTSAG--DITGVDALTLTV-NQTLNNHASGKLLSAGVLTL-----KADSVK 1015
Query 3014 QTSTSESKSLTYVNSEVTL-NKTEGRLNSLNIKGGEVSIQDRGNLQVNNIHVESLQDTAS 3072
+ + T ++T +G +L GG V+ + G L N S
Sbjct 1016 NDGQLQGNATTITAGQLTNGGHLQGETLTLTASGG-VNNRSGGVLMSRNAL------NVS 1068
Query 3073 SSNSSRGGSIGGGYGSGSKNITASYNQSKGSSDSAWVNTTSKLL-IGNAQNDANLDAMGV 3131
++ S G+I GG G N K S S T L G+ A + V
Sbjct 1069 TATLSNQGTIQGGGGVSLNATDRLQNDGKILSGSNLTLTAQVLANTGSGLVQAATLLLDV 1128
Query 3132 KNITNIGGVIANANKNADGSLTDHKNLNYTGNLELKDLQDHNNNNSSGFNVSTNIGIPQG 3191
N N G V+A + + G+ LN TG L+ DL + + S N T +G
Sbjct 1129 VNTVNGGRVLATGSADVKGT-----TLNNTGTLQGADLLVNYHTFS---NSGTLLGTSGL 1180
Query 3192 GSKAASTAPKGS 3203
G K +S G+
Sbjct 1181 GVKGSSLLQNGT 1192
Score = 63.9 bits (154), Expect = 6e-12
Identities = 241/1160 (21%), Positives = 408/1160 (35%), Gaps = 163/1160 (14%)
Query 2170 GIALTAAQTAQLTSDIVWLVEQSVTLPDGTITKA-LVPQVYVKVRVGDLKGDGTLLSGNS 2228
G LTA+ T LT D L + L GT+ + V + + L G+LLSG
Sbjct 397 GQNLTASATT-LTQDGTLLAKGHAGLDAGTLNNSGAVQGASLTLGSTTLSNSGSLLSGGP 455
Query 2229 VNLKLDGDLINGATIAGREALQITADNVQNLNGRIQGNQVAIETQKDLNNIGGQIIAKDA 2288
+ + +G T A + + ITA G + + V + +D+ G
Sbjct 456 LTVNTRDFTQSGRTGA-KGKVDITASGKLTSTGSLVSDDVLVLKAQDVTQNG-------- 506
Query 2289 MALKVGGNLNIESTTRTSESKVGNFSSSITNVDRVAGLYVGNGSTKQLDPNQA---TLML 2345
L G L + + +S K S+T+ D L N +T LD + TL +
Sbjct 507 -VLSGGKGLTVSAQALSSGKK------SVTHSDAAMTL---NVTTVALDGENSAGDTLRV 556
Query 2346 NVAGNSSLKGVQINNSNSATVLNTTGNVDLGTVSVGKQETLKIDDKNGYQLKQQQDVGSQ 2405
S+ G Q+ + + ++ N GT + + + +K + K
Sbjct 557 QADKLSTAAGAQLQSGKNLSI-NARDARLAGTQAAQQTMAVNASEKLTHSGKS------- 608
Query 2406 IKSAGSLLINGQNITSKAVDLNSQQGDIQLSAQKDIVLDNGLNQSTVSSQSQSKGSFGGK 2465
SA SL ++ +TS V + S L+ Q + ++GL Q S ++ +
Sbjct 609 --SAPSLSLSAPELTSSGVLVGSA-----LNTQSQTLTNSGLLQGEASLTVNTQRLDNQQ 661
Query 2466 KSSTYDASSST-SIANQLNAGQNIIINSAQGNISATHLQAEAGNNIQIHAQQGNV--TLL 2522
+ Y A+ T I + N+G G+ T A N +I A NV T L
Sbjct 662 NGTLYSAADLTLDIPDIRNSGL------ITGDNGLTLNTASLSNPGKIIADTLNVRATTL 715
Query 2523 SAIDDKRESSTSSKKGVATYNNRQSGYIDQEVAQTTLKAGDTVDINAAKNIELQAND-VQ 2581
+ + + G R ++ K T +N+ +QA++
Sbjct 716 DGDGLLQGAGALALAGDTLSQGRNGRWLTAGDLSLRGKTLHTAGTTQGQNLTVQADNWAN 775
Query 2582 AGNSIYVGNTLMQRQADGSLKAADGSLMPENVTLSTLATKDEQW----------DEQQKG 2631
+G+ + GN + A G L + G +M + T AT D + D
Sbjct 776 SGSVLATGN--LTASATGQLTST-GDIMSQGDTTLNAATTDNRGSLLSAGTLSLDGNSLD 832
Query 2632 YRGIVKD---IVKATAVGLAGIEALAPGLKAPKITVSESTGKRTEQISQTGSSLKADNVY 2688
RG V+ ++ +V +G G+ A + + G SL
Sbjct 833 NRGTVQGNHVTIRQNSVTNSGT---LTGIAALTLAARMDMASPQPALMNNGGSLL----- 884
Query 2689 VGSSGQTTLTSTDITAKNTILLGQKVTLNAAEEQKITVESTSKETVQGLGAKLNKDSIRL 2748
+SG T+T+ IT+ G++V + A S + + L A+L + +
Sbjct 885 --TSGDLTITAGSITSSGH-WQGKQVLITADS----LANSGAIQAADSLTARLTGELVST 937
Query 2749 GGFVLEDASQSSKTTETTHKLGSINTENLKIQG--------VEGVDILGQNITATGDTLI 2800
G + + + + G +NL ++ + GVD L + TL
Sbjct 938 AGSKVTSNGEMALSALNLSNSGQWIAKNLTLKANSLTSAGDITGVDALTLTVN---QTLN 994
Query 2801 DHGRGDLNVGGYENKTTVEDKTHVETISTEVGVRNAYLDAALALGAVKDAAEAVKQAKDQ 2860
+H G L G V T+ + V+N D L A A +
Sbjct 995 NHASGKLLSAG------------VLTLKAD-SVKN---DGQLQGNATTITAGQLTNGGHL 1038
Query 2861 YSQAQRDYASGKITKEA----LDDSKANVAMATANLANAQIAVGSAAATAAASSATYGFT 2916
+ ASG + + + + NV+ AT + G + A G
Sbjct 1039 QGETLTLTASGGVNNRSGGVLMSRNALNVSTATLSNQGTIQGGGGVSLNATDRLQNDGKI 1098
Query 2917 IGANGERIETTNTTNTTQGKWQGSTLELNNLTLKSENQDVNVQGSRLTATGTTSFDGTKD 2976
+ + + NT G Q +TL L+ + V G R+ ATG+ GT
Sbjct 1099 LSGSNLTLTAQVLANTGSGLVQAATLLLDVVN--------TVNGGRVLATGSADVKGTT- 1149
Query 2977 LNVTAGTEHSQQETSSKT--NSQSVSYTYGGGGSASIGKQTSTSESKSLTYVNSEVTLNK 3034
LN T + + + T NS ++ T G G S Q T Y + L+
Sbjct 1150 LNNTGTLQGADLLVNYHTFSNSGTLLGTSGLGVKGSSLLQNGTGR----LYSAGNLLLDA 1205
Query 3035 TEGRLNSLNIKGGEVSIQ------DRGNLQVNNIHVESLQDTASSSNSSRGGSIGGGYGS 3088
+ + G+V+++ + G L + Q+ ++ +G ++ G G
Sbjct 1206 QDFSGQGQVVATGDVTLKLIAALTNHGTLAAGKTLSVTSQNAITNGGVMQGDAMVLGAGE 1265
Query 3089 GSKN---ITASYNQSKGSSDSAWVNTTSKLLIGNAQNDANLDAMGVKNITNIGGVIANAN 3145
N +TA S S+ ++N L G D +L++ I+ G +
Sbjct 1266 AFTNNGMLTAGKGNSVFSAQRLFLNAPGSLQAGG---DVSLNSRSDITISGFTGTAGSLT 1322
Query 3146 KNADGSLTDHKNLNYTGNLELKDLQDHNNNNSSGFNVSTNIGIPQGGSK-AASTAPKGST 3204
N G+L + + NL+L + HN + I G S A G+
Sbjct 1323 MNVAGTLLNSALIYAGNNLKLFTDRLHNQHGD----------ILAGNSLWVQKDASGGAN 1372
Query 3205 TIGLNSSGQ-ETEQ-----LTKATLGQGSVTNATADTNRDINNTQEITRDQTTGMLNGSV 3258
T +N+SG ET Q T L Q +AT T + ++ Q GM N V
Sbjct 1373 TEIINTSGNIETHQGDIVVRTGHLLNQREGFSATTTTRTNPSSIQ--------GMGNALV 1424
Query 3259 TVDHRLLSESGRAEIVKEQE 3278
+ LL + +E E
Sbjct 1425 DIPLSLLPDGSYGYFTREVE 1444
Score = 55.5 bits (132), Expect = 2e-09
Identities = 115/523 (22%), Positives = 190/523 (36%), Gaps = 79/523 (15%)
Query 2733 TVQGLGAKLNKDSIRLGGFVLEDASQSSKTTETTHKLGSINTENLKIQGVEGVDILGQNI 2792
T G+G L R G L DAS G + N G V GQ +
Sbjct 261 TESGVGVNLGNLYARDGDITL-DAS------------GRLTVNNSLATGA--VTAKGQGV 305
Query 2793 TATGDTLIDHGRGDLNVGG-----YENKTTVEDKTHVETISTEVGVRNAYLDAALALGAV 2847
T TGD G+L+V N T DK T + +N L A V
Sbjct 306 TLTGD---HKAGGNLSVSSRSDIVLSNGTLNSDKDLSLTAGGRITQQNEKLTAGRD---V 359
Query 2848 KDAAEAVKQAKDQYSQAQRDYASGKITKEALDDSKANVAMATANLANAQIAVGSAAATAA 2907
AA+ + Q A RD + ++ + L QI G TA+
Sbjct 360 TLAAKNITQDTASQINAARDIVT--VSSDTLT-------------TQGQITAGQNL-TAS 403
Query 2908 ASSATYGFTIGANGERIETTNTTNTTQGKWQGSTLELNNLTLKSENQ-----DVNVQGSR 2962
A++ T T+ A G T N + G QG++L L + TL + + V
Sbjct 404 ATTLTQDGTLLAKGHAGLDAGTLNNS-GAVQGASLTLGSTTLSNSGSLLSGGPLTVNTRD 462
Query 2963 LTATGTTSFDGTKDLNVTA-----GTEHSQQETSSKTNSQSVSYTYGGGGSASIGKQTST 3017
T +G T G D+ + G+ S K + + GG ++ Q +
Sbjct 463 FTQSGRTGAKGKVDITASGKLTSTGSLVSDDVLVLKAQDVTQNGVLSGGKGLTVSAQALS 522
Query 3018 SESKSLTYVNSEVTLNKTEGRLNSLNIKGGEVSIQDRGNLQVNNIHVESLQDTASSSNSS 3077
S KS+T+ ++ +TLN T L+ N G + +Q A +++
Sbjct 523 SGKKSVTHSDAAMTLNVTTVALDGENSAGDTLRVQ------------------ADKLSTA 564
Query 3078 RGGSIGGGYGSGSKNITASYNQSKGSSDSAWVNTTSKLLIGNAQNDANLDAMGVKNITNI 3137
G + G A ++ + + VN + KL + +L ++ +T+
Sbjct 565 AGAQLQSGKNLSINARDARLAGTQAAQQTMAVNASEKLTHSGKSSAPSL-SLSAPELTSS 623
Query 3138 GGVIANANKNADGSLTDHKNLNYTGNLELKDLQDHNNNNSSGFNVS-TNIGIPQGGSKAA 3196
G ++ +A +LT+ L +L + + N N + ++ + + IP +
Sbjct 624 GVLVGSALNTQSQTLTNSGLLQGEASLTVNTQRLDNQQNGTLYSAADLTLDIPDIRNSGL 683
Query 3197 STAPKGST--TIGLNSSGQ---ETEQLTKATL-GQGSVTNATA 3233
T G T T L++ G+ +T + TL G G + A A
Sbjct 684 ITGDNGLTLNTASLSNPGKIIADTLNVRATTLDGDGLLQGAGA 726
Score = 45.8 bits (107), Expect = 2e-06
Identities = 173/913 (19%), Positives = 307/913 (34%), Gaps = 112/913 (12%)
Query 333 VRNAGSMNSTQSTLTLNANGDLTNTGNLIANQGQLQLNAENIKNTGNISSATSQVSLHSQ 392
VR G+ ++ T+NA D+T + + G + +NA ++ ++ S
Sbjct 2179 VRQQGTEIASGGDTTVNAGRDITAVASSVTATGNISVNAG--RDVALTTATESDYHYLET 2236
Query 393 NLDNSGLISSADELNIQQQGH--------VGNRGTLNAA-RIVVDAGSLANSGSIEQTGA 443
+ G +S I + GNR T+NA + V+ + +
Sbjct 2237 KKKSGGFLSKKTTHTISEDSASREAGSLLSGNRVTVNAGDNLTVEGSDVVADQDVSLAAG 2296
Query 444 QALDLKAGSMSNIGGKIGIAKTSSTGGNGSESGGGSQPVEPNNAAQDGGSLEVVNTDSTP 503
+D+ A + ++ + K S G +GG + + D + S
Sbjct 2297 NHVDVLAATSTDTSWRFKETKKSGLMG----TGGIGFTIGSSKTTHDRREAGTTQSQSAS 2352
Query 504 TTPKTYETGYIHVRDQLNNDQGAIVAQGGIDLESNNGLDNQGGQLNLGRVKIQGERFNND 563
T T I Q + ++A I + ++ + + G + E+F
Sbjct 2353 TIGSTAGNVSITAGKQAHISGSDVIANRDISITGDSVVVDPGHDR-----RTVDEKFEQK 2407
Query 564 QGQLTVKQAEIQTNSLSN-----QSGQLISNQKLNIQTQTANNQKGKIQSVDQLDLNVAN 618
+ LTV + ++++N Q + S+ +L T G +Q+ + A
Sbjct 2408 KSGLTVALSGTVGSAINNAVTSAQETKESSDSRLKALQATKTALSG-VQAGQAAAMATAT 2466
Query 619 GLNNIEGQIASGQQLNIQADQVNNQSGLIYSEQQGIELKANHAI----------NNTSGI 668
G N A+G L++ + +Q G L A + + +N I
Sbjct 2467 GDPN-----ATGVSLSLTTQKSKSQQHSESDTVSGSTLNAGNNLSVVATGKNRGDNRGDI 2521
Query 669 IQAKTQLNL-ASTQLDNTSGHIQAENIQQQHTTVNNTQGSIVAGQSL--------ISTVD 719
+ A +QL +T LD + + + Q TT N+ G S+ IS
Sbjct 2522 VIAGSQLKAGGNTSLDAANDVLLSGAANTQKTTGRNSSSGGGVGVSIGAGGNGAGISVFA 2581
Query 720 QFDNHQGLIDAKNIQLTHQVLN-------NSGSIYADQNIKITGQHILNTGSIAAGQNIQ 772
+ +G + T ++ NSG ++ G I+ + Q
Sbjct 2582 SVNAAKGSEKGNGTEWTETTIDSGKTVTINSGRDTVLNGAQVNGNRIIADVGHDLLISSQ 2641
Query 773 LNTAKLQHEQAALIAAGLDRQGKLTSTGDL-----------DITAEQTTLHGQSFAGQQL 821
+T+K +Q ++ A G G +T +G + D AEQT + G +
Sbjct 2642 QDTSKYDSKQTSVAAGGSFTFGSMTGSGYIAASRDKMKSRFDSVAEQTGMFSGD-GGFDI 2700
Query 822 KVASKQQIDATNGQLQAKNIDLASDAGDISTRAATVIAEQLSLK-SHDLIDNQQGTLSAQ 880
V + Q+D G + A ++ D T + I + K SH I G
Sbjct 2701 TVGNHTQLD---GAVIASTATADKNSLDTGTLGFSDIHNEADYKVSHSGISLSGGGSFGD 2757
Query 881 --QLNLTANRLDNTQGHILHT-GQDQLDLNFSQSLNNQLGEIRSNAAELNIKTALLNNTE 937
Q N+ + + GH H G Q + + N A L+ A N++
Sbjct 2758 KFQGNMPGGMI-SAGGHSGHAEGTTQAAVADGTITIRDRDNQKQNLANLSRDPAHANDSI 2816
Query 938 GQVVHAGTQQLNIQTAQLNGHLGHILSN-----GTLQLKAGTLDVSGGV----TSADQIT 988
+ +Q +QT L +G +++ G L D G V T +
Sbjct 2817 SPIFDKEKEQRRLQTVGLISDIGSQVADIARTQGELNALKAAQDKYGPVPADATEEQRQA 2876
Query 989 IQANVLNNAQ----------GQLIQRGTSNPLNLTIQQQLNNQAGLIQSATATDIKAGSL 1038
A + + + G IQRG N AG + A+A ++
Sbjct 2877 YLAKLRDTPEYKKEQEKYGTGSEIQRGIQAATAALQGLAGGNLAGALAGASAPELAHLLK 2936
Query 1039 NNQR-------------GTLSSAQGQNLDVDVAGKLDNSQSGQIYAGNQAHLQVGSIDNS 1085
+ ++ GT+++ QG N+ AG + + AG + V D S
Sbjct 2937 STEKDPAVNAIAHAILGGTVAAMQGNNVAAGAAGAATGELAARAIAG-MLYPGVKQSDLS 2995
Query 1086 HQGQINAQQNLQLTSQQQINNQSGQIVANGDVQIQSQGLNNSHGQMGSLQGGLSLNTGSD 1145
+ Q L S +G A+ V QS G N S+ L
Sbjct 2996 EE-QKQTISTLATVSAGLAGGLTGNSTASAAVGAQS-GKNAVENNYLSVSEKTELEIAKQ 3053
Query 1146 TLINQSGLIQAKK 1158
TL N + +K
Sbjct 3054 TLKNSKDPAEREK 3066
Score = 45.4 bits (106), Expect = 2e-06
Identities = 167/840 (20%), Positives = 306/840 (36%), Gaps = 126/840 (15%)
Query 1216 SSAQGNLTLNAGNGTLTNQAATIVSGKTLTL-SANQLDNSNHGQINSQNNADISIVKDIN 1274
S GN AG G +TN +I + L+L S +DN N G I++ + D+S + DI+
Sbjct 1876 SVISGNNVQLAG-GNITNSGGSINAQNGLSLDSTGYIDNLNAGLISAGGSLDLSAIGDIS 1934
Query 1275 NTSGVIAAKQQLILSSQG-----------------------LNNT-TGQIGTVQG--NLH 1308
N S VI+ K + S G L+ T TG + T++G +L
Sbjct 1935 NISSVISGKTVQLESVSGNISNITRRQQWNAGSDSRYGGVHLSGTDTGPVATIKGTDSLS 1994
Query 1309 IDAGSQLLNNQQGRIQSGQDLNLNATGIDNTQGQISSKNQLQLDSREQLLNNRQGTLSAE 1368
+DAG + + + SG L ++A N + S ++ Q N+ T S
Sbjct 1995 LDAGKNI-DITGATVSSGGTLGMSAGNDINIAANLISGSKSQSGFWHTDDNSASSTTSQG 2053
Query 1369 NLTIDSGELNNDQGLIQAQQSIQIDTHQHNLSNTNSGAQGG---ILSQGN-IQLNNIQTL 1424
+ G L G HNL T S G +LS GN + LN ++
Sbjct 2054 SSISAGGNLAMAAG--------------HNLDVTASSVSAGHSALLSAGNDLSLNAVRES 2099
Query 1425 DNQQGYLASAQQLDLQANQVF-NQNGTLLAAKQLNLQGTGQNQLLNNQSGQMLSMGGMNL 1483
N + + + + + V N L+A + + Q G N ++ GG ++
Sbjct 2100 KNSRNGRSESHESHAAVSTVTAGDNLLLVAGRDVASQAAGVAAENN-----VVIRGGRDV 2154
Query 1484 NIDQINNKGKANTADA-DSHIMAAG-ELNITTQQLDNQNTLNTDPANTSIQGIDANTLNV 1541
N+ A +A A DS+ E+N T +Q + D + + I A +V
Sbjct 2155 NL-------VAESAGAGDSYTSKKKKEINETVRQQGTEIASGGDTTVNAGRDITAVASSV 2207
Query 1542 TS----KVLNNQSGVIRSSADQNLNVQQALNNQSGQISSEKQLTLVGDQLEINNLNGQIL 1597
T+ V + + ++ + + + + G +S + T+ D + G +L
Sbjct 2208 TATGNISVNAGRDVALTTATESDYHYLETKKKSGGFLSKKTTHTISEDSA--SREAGSLL 2265
Query 1598 AGTALDLIA-QSLSGDGK-LLSLGNAKLSLQNDYIHSSGAQLQANQDLSLSTKGNIINNG 1655
+G + + A +L+ +G +++ + L+ N + + + K ++ G
Sbjct 2266 SGNRVTVNAGDNLTVEGSDVVADQDVSLAAGNHVDVLAATSTDTSWRFKETKKSGLMGTG 2325
Query 1656 TINAGNQLALNAANITNQQAGKIESHDTRLTAQNTLNNTGLINGDFTRLQAETLNNQGTG 1715
I G + + ++AG +S T +T N + G + +
Sbjct 2326 GI--GFTIGSSKTTHDRREAGTTQSQSAS-TIGSTAGNVSITAGKQAHISGSDVIANRDI 2382
Query 1716 RIYGTTLAIQAN----TLNNQPDSTGTAPVIASRGDLHLGVQTLNNLSNPTDYTSQALIF 1771
I G ++ + T++ + + + +A G + + + T +S + +
Sbjct 2383 SITGDSVVVDPGHDRRTVDEKFEQKKSGLTVALSGTVGSAINNAVTSAQETKESSDSRL- 2441
Query 1772 SAGNLYLGAALDANDYATGQADVIHNESATIESLGDMNLSAKQINNINKYFKTEQVEVSR 1831
AL A A +A + GD N + ++ + K++Q S
Sbjct 2442 --------KALQATKTALSGVQA-GQAAAMATATGDPNATGVSLSLTTQKSKSQQHSESD 2492
Query 1832 KDGLEKYCDAWCTFDGNYYD-GNPYEDWMRYYYSEITYETRTTES-----APGQIKAGGH 1885
T G+ + GN T + R A Q+KAGG+
Sbjct 2493 ------------TVSGSTLNAGNNLS-------VVATGKNRGDNRGDIVIAGSQLKAGGN 2533
Query 1886 LDLNGAQVV----NDKSQILAGGELKNEGG---TIDSGTQIAGIRKIVNTGTQVKYWKYE 1938
L+ A V +Q G + GG +I +G AGI + K
Sbjct 2534 TSLDAANDVLLSGAANTQKTTGRNSSSGGGVGVSIGAGGNGAGISVFASVNAAKGSEKGN 2593
Query 1939 G-QWDNPFENSSET-TFDLSISQALGNQNLNQNQL-----STVAVSNNQSAEHIQNSQTT 1991
G +W +S +T T + L +N N++ + +S+ Q + QT+
Sbjct 2594 GTEWTETTIDSGKTVTINSGRDTVLNGAQVNGNRIIADVGHDLLISSQQDTSKYDSKQTS 2653
Score = 38.1 bits (87), Expect = 4e-04
Identities = 138/733 (19%), Positives = 261/733 (36%), Gaps = 140/733 (19%)
Query 1878 GQIKAGGHLDLNGAQVVNDKSQILAGG--ELKNEGGTIDSGTQIAGIRKIVNTGTQVKYW 1935
G I AGG LDL+ +++ S +++G +L++ G I + T+ R+ N G+ +Y
Sbjct 1917 GLISAGGSLDLSAIGDISNISSVISGKTVQLESVSGNISNITR----RQQWNAGSDSRY- 1971
Query 1936 KYEGQWDNPFENSSETTFDLSISQALGNQNLNQNQLSTVAVSNNQSAEHIQNSQTTQQEI 1995
G +L+ VA + + + +I
Sbjct 1972 --------------------------GGVHLSGTDTGPVATIKGTDSLSLDAGKNI--DI 2003
Query 1996 NGLQTSNNNT-QLNQTKDVDLDQLNLKDSQSQ----NAPQASAVETVQQQSATSAPSSTP 2050
G S+ T ++ D+++ + S+SQ + SA T Q S+ SA +
Sbjct 2004 TGATVSSGGTLGMSAGNDINIAANLISGSKSQSGFWHTDDNSASSTTSQGSSISAGGNLA 2063
Query 2051 QGTSEEIRSIDFSNIKVPNSALYKVNADSKAGYLIETDPAFADYKKWLSSDYMLDALGLD 2110
+ + S++ +SAL D L L+
Sbjct 2064 MAAGHNL-DVTASSVSAGHSALLSAGND----------------------------LSLN 2094
Query 2111 PALQQKRLGDGFYEQRLVQDQIANLTGYRFLEGFANDDEQYKALMNNGITFAKLYGLRPG 2170
+ K +G E ++ +T L A D +A G+ +R G
Sbjct 2095 AVRESKNSRNGRSESHESHAAVSTVTAGDNLLLVAGRDVASQAA---GVAAENNVVIRGG 2151
Query 2171 IALTAAQTAQLTSDIVWLVEQSVTLPDGTITKALVPQVYVKVRVGDLKGDGTLLSGNSVN 2230
+ + D S T V Q ++ G GD T+ +G +
Sbjct 2152 RDVNLVAESAGAGD-------SYTSKKKKEINETVRQQGTEIASG---GDTTVNAGRDIT 2201
Query 2231 LKLDGDLING--ATIAGREALQITA--------DNVQNLNGRIQGNQVAIETQKDLNNIG 2280
G + AGR+ TA + + G + ++ +
Sbjct 2202 AVASSVTATGNISVNAGRDVALTTATESDYHYLETKKKSGGFLSKKTTHTISEDSASREA 2261
Query 2281 GQIIAKDAMALKVGGNLNIESTTRTSESKV----GNFSS--SITNVD--------RVAGL 2326
G +++ + + + G NL +E + ++ V GN + T+ D + +GL
Sbjct 2262 GSLLSGNRVTVNAGDNLTVEGSDVVADQDVSLAAGNHVDVLAATSTDTSWRFKETKKSGL 2321
Query 2327 YVGNGSTKQLDPNQATLMLNVAGNSSLKGVQINNSNSATVLNTTGNVDLGTVSVGKQETL 2386
G + ++ T AG + + +++T+ +T GNV +++ GKQ +
Sbjct 2322 MGTGGIGFTIGSSKTTHDRREAGTT-------QSQSASTIGSTAGNV---SITAGKQAHI 2371
Query 2387 KIDDKNGYQLKQQQDVGSQIKSAGSLLINGQNITSKAVDLNSQQGDIQLSAQKDIVLDNG 2446
+G + +D I G ++ + VD +Q L+ + +
Sbjct 2372 -----SGSDVIANRD----ISITGDSVVVDPGHDRRTVDEKFEQKKSGLTVALSGTVGSA 2422
Query 2447 LNQSTVSSQSQSKGSFGGKKSSTYDASSSTSIA-NQLNAGQNIIINSAQGNISATHLQAE 2505
+N + S+Q + S S A +T A + + AGQ + +A G+ +AT
Sbjct 2423 INNAVTSAQETKESS-----DSRLKALQATKTALSGVQAGQAAAMATATGDPNAT----- 2472
Query 2506 AGNNIQIHAQQGNVTLLSAIDDKRESSTSSKKG---VATYNNRQSGYIDQEVAQTTLKAG 2562
G ++ + Q+ S D S+ ++ VAT NR D +A + LKAG
Sbjct 2473 -GVSLSLTTQKSKSQQHSESDTVSGSTLNAGNNLSVVATGKNRGDNRGDIVIAGSQLKAG 2531
Query 2563 DTVDINAAKNIEL 2575
++AA ++ L
Sbjct 2532 GNTSLDAANDVLL 2544
Score = 28.1 bits (61), Expect = 0.39
Identities = 36/169 (21%), Positives = 71/169 (42%), Gaps = 21/169 (12%)
Query 660 HAINNTSGIIQAKTQLNLASTQLDNTSGHIQAENIQQQHTTVNNTQGSIVAGQSLISTVD 719
+A+ N + KT+L +A L N+ + E QQ++ + + I + + +I+
Sbjct 3033 NAVENNYLSVSEKTELEIAKQTLKNSKDPAEREKAQQKYDAL--LEKDIASDKEVIAACS 3090
Query 720 QFDNHQGLIDAKNIQLTHQVLNNSG-------SIYADQNIKITGQ--HILNTGSIAAGQN 770
+ + +++ + + G S Y+ Q GQ ++L+ S+ A
Sbjct 3091 NGNASSSACASARLKV---IASKEGYEDGPYNSKYSQQYADAYGQIVNLLDITSVDAQNQ 3147
Query 771 IQLNTAKLQHEQAALIAAGLDRQG----KLTSTGDLDITAEQTTLHGQS 815
Q+ A + + ++ G+DRQ T+ G I A T L GQ+
Sbjct 3148 QQVKNAMINY---FMVTKGVDRQTAESYTETTQGLEIIAASVTPLIGQA 3193
Score = 25.8 bits (55), Expect = 2.0
Identities = 10/30 (33%), Positives = 19/30 (63%), Gaps = 0/30 (0%)
Query 1886 LDLNGAQVVNDKSQILAGGELKNEGGTIDS 1915
+ L+ V++ + LAGG + N GG+I++
Sbjct 1870 ITLHNGSVISGNNVQLAGGNITNSGGSINA 1899
Score = 23.9 bits (50), Expect = 7.5
Identities = 20/79 (25%), Positives = 31/79 (39%), Gaps = 2/79 (3%)
Query 3414 GMTILSNIADLGNSIKDISESTGVDIEKVQLAVGLLISGPVRLVIESGKSMAVDSVVGEK 3473
G I N+ NS+ + TGVD + + L +L+ ++ DSV +
Sbjct 959 GQWIAKNLTLKANSLTSAGDITGVDALTLTVNQTLNNHASGKLLSAGVLTLKADSVKNDG 1018
Query 3474 VAQG--VDILANSMTAAAH 3490
QG I A +T H
Sbjct 1019 QLQGNATTITAGQLTNGGH 1037
>Q0T963 tRNA nuclease CdiA [Escherichia coli O6:K15:H31 (strain
536 / UPEC)]
Length=3242
Score = 367 bits (941), Expect = 9e-104
Identities = 418/1564 (27%), Positives = 692/1564 (44%), Gaps = 179/1564 (11%)
Query 107 SSNGVTQVNIQTPSAGGVSRNTYSQFDVGQEGAILNNARNNTQ-TQLGGWIQGNPWL-AK 164
++NGV VNI TP+ G+S N ++ ++VG+EG ILNNA TQLGG IQ NP L A
Sbjct 45 AANGVPVVNIATPNGAGISHNRFTDYNVGKEGLILNNATGKLNPTQLGGLIQNNPNLKAG 104
Query 165 GEAKVILNEVNSSNPSQLKGYIEVAGKQAQVVIANPSGLVCDGCGVINADRFTLTTGQAV 224
GEAK I+NEV N S L+GY EVAGK A V++ANP G+ CDGCG IN TLTTG+ V
Sbjct 105 GEAKGIINEVTGGNRSLLQGYTEVAGKAANVMVANPYGITCDGCGFINTPHATLTTGRPV 164
Query 225 MN-QGYLESFRVREGQITIQGKGLNGSLTPFTDVYARALQVNAGLYAKELNVVLGQNDIN 283
MN G L++ V EG ITI G GL+G+ + + ARA +VNA L+AK+L V G N I
Sbjct 165 MNADGSLQALEVTEGSITINGAGLDGTRSDAVSIIARATEVNAALHAKDLTVTAGANRIT 224
Query 284 VNDPTTSNVSPIQSNTSANNKPQFALDVGQLGGMYAGKIFLVGTEQGVGVRNAGSMNSTQ 343
+ VS ++ + P+ A+D G LGGMYA +I L TE GVGV N G++ +
Sbjct 225 AD----GRVSALKGE---GDVPKVAVDTGALGGMYARRIHLTSTESGVGV-NLGNLYARD 276
Query 344 STLTLNANGDLT-----NTGNLIANQGQLQLNAENIKNTGNIS-SATSQVSLHSQNL--D 395
+ L++ G L GN + L+ +N K GN+S + T+ ++L+ L D
Sbjct 277 GDIILSSAGKLVLKNSLAGGNTTVTGTDVSLSGDN-KAGGNLSVTGTTGLTLNQPRLVTD 335
Query 396 NSGLISSADELNIQQQGHV--GNRGTLNAARIVVDAGSLANSGSIEQTGAQALDLKAGSM 453
+ ++SS+ ++ +Q G + G L+A + +G++ + ++ T LK S
Sbjct 336 KNLVLSSSGQI-VQNGGELTAGQNAMLSAQHLNQTSGTVNAAENVTLTTTNDTTLKGRS- 393
Query 454 SNIGGKIGIAKTSSTGGNGSESGGGSQPVE----PNNAAQDGGSLEVVNTDSTPTTPKTY 509
I GK + S G+ G V+ N G L+V TD T T
Sbjct 394 --IAGKTLTVSSGSLNNGGTLVAGRDATVKTGTFSNTGTVQGNGLKVTATDLTST----- 446
Query 510 ETGYIHVRDQLNNDQGAIVAQGGIDLESNNG-LDNQGGQLNLGRVKIQGERFNNDQGQLT 568
G+I + +D+ + N L G + RV + G N +G+L
Sbjct 447 ---------------GSIKSGSTLDISARNATLSGDAGAKDSARVTVSGTLEN--RGRLV 489
Query 569 VKQAEIQTNSLSNQSGQLISNQKLNIQTQTANNQKGKIQSVDQLDLNVANGLNNIEGQIA 628
+ + N SG L ++L T + + + D +L + + + + G+ +
Sbjct 490 SDDVLTLSATQINNSGTLSGAKELVASADTLTTTEKSVTNSDG-NLMLDSASSTLAGETS 548
Query 629 SGQQLNIQADQV------NNQSGLIYSEQQGIELKANHAINN----------TSGIIQAK 672
+G ++++ + + Q + + Q +L A + T +
Sbjct 549 AGGTVSVKGNSLKTTTTAQTQGNSVSVDVQNAQLDGTQAARDILTLNASEKLTHSGKSSA 608
Query 673 TQLNLASTQLDNTSGHIQAENIQQQHTTVNNTQGSIVAGQSLISTVDQFDNHQG--LIDA 730
L+L++ +L +SG + + Q T+ N+ G + SL + DN Q L A
Sbjct 609 PSLSLSAPEL-TSSGVLVGSALNTQSQTLTNS-GLLQGEASLTVNTQRLDNQQNGTLYSA 666
Query 731 KNIQLTHQVLNNSGSIYADQNIKITGQHILNTGSIAAGQNIQLNTAKLQHEQAALIAAGL 790
++ L + NSG I D + + + N G I A + + L + A L
Sbjct 667 ADLTLDIPDIRNSGLITGDNGLMLNAVSLSNPGKIIA-DTLSVRATTLDGDGLLQGAGAL 725
Query 791 DRQGKLTSTGDLD--ITAEQTTLHGQSF------AGQQLKVASKQQIDATNGQLQAKNID 842
G S G +TA+ +L G++ GQ + V + + A +G + A
Sbjct 726 ALAGDTLSQGSHGRWLTADDLSLRGKTLNTAGTTQGQNITVQADRW--ANSGSVLATGNL 783
Query 843 LASDAGDISTRAATVIAEQLSLKSHDLIDNQQGTLSAQQLNLTANRLDNT---QGHILHT 899
AS G +++ + +LK+ DN+ LSA L+L N LDN+ QG H
Sbjct 784 TASATGQLTSTGDIMSQGDTTLKA-ATTDNRGSLLSAGTLSLDGNSLDNSGTVQGD--HV 840
Query 900 GQDQLDLNFSQSLNNQLGEIRSNAAELNIKTALLNN------------TEGQVVHAGT-Q 946
Q + S +L + + A ++ + AL+NN T G +V++G Q
Sbjct 841 TIRQNSVTNSGTLTG-IAALTLAARMVSPQPALMNNGGSLLTSGDLTITAGSLVNSGAIQ 899
Query 947 QLNIQTAQLNGHL-----GHILSNGTLQLKAGTLDVSGGVTSADQITIQANVLNNAQGQL 1001
+ TA+L G L + SNG + L A L + G A +T++AN L +A G +
Sbjct 900 AADSLTARLTGELVSTAGSKVTSNGEMALSALNLS-NSGQWIAKNLTLKANSLTSA-GDI 957
Query 1002 IQRGTSNPLNLTIQQQLNNQA-GLIQSATATDIKAGSLNNQ-----------RGTLSSA- 1048
T L LT+ Q LNNQA G + SA +KA S+ N G L++
Sbjct 958 TGVDT---LTLTVNQTLNNQANGKLLSAGVLTLKADSVTNDGQLQGNATTITAGQLTNGG 1014
Query 1049 --QGQNLDVDVAGKLDNSQSGQIYAGNQAHLQVGSIDNSHQGQINAQQNLQLTSQQQINN 1106
QG+ L + +G ++N G + + N ++ ++ N QG I + L ++ N
Sbjct 1015 HLQGETLTLAASGGVNNRFGGVLMSRNALNVSTATLSN--QGTIQGGGGVSLNVTDRLQN 1072
Query 1107 QSGQIVANGDVQIQSQGLNNSHGQMGSLQGGLSLNTGSDTLINQSGLIQAKKDIGIQAQR 1166
S +I++ ++ + +Q L N+ G +Q L +T+ G + A ++
Sbjct 1073 DS-KILSGSNLTLTAQVLANTGS--GLVQAATLLLDVVNTV--NGGRVLATGSADVKGTT 1127
Query 1167 IDNQQGQITTQGQAELISQAEIDNLEGAIAADLDVNIR-SQGLNNNKGQISSAQGNLTLN 1225
++N T QG L++ N G + + ++ S L + G++ SA GNL L+
Sbjct 1128 LNNTG---TLQGADLLVNYHTFSN-SGTLLGTSGLGVKGSSLLQHGTGRLYSA-GNLLLD 1182
Query 1226 AGNGTLTNQAATIVSGK-TLTLSANQLDNSNHGQINSQNNADISIVKDINNTSGVIAAKQ 1284
A + + Q + +G TL L A +NHG + + ++ I N GV+
Sbjct 1183 AQD--FSGQGQVVATGDVTLKLIAAL---TNHGTLAAGKTLSVTSQNAITN-GGVMQGDA 1236
Query 1285 QLILSSQGLNNTTGQIGTVQGNLHIDAGSQLLNNQQGRIQSGQDLNLNATGIDNTQGQIS 1344
++ + + N G + +GN + + +L N G +Q+G D++LN+ G
Sbjct 1237 MVLGAGEAFTN-NGMLTAGKGN-SVFSAQRLFLNAPGSLQAGGDVSLNSRSDITISGFTG 1294
Query 1345 SKNQLQLDSREQLLNNRQGTLSAENLTIDSGELNNDQGLIQAQQSIQIDTHQHNLSNTNS 1404
+ L ++ LLN+ + NL + + L+N G I A S+ + +NT
Sbjct 1295 TAGSLTMNVAGTLLNSAL-IYAGNNLKLFTDRLHNQHGDILAGNSLWVQKDASGGANTEI 1353
Query 1405 GAQGGILS--QGNIQLNNIQTLDNQQGYLASAQQLDLQANQVFNQNGTLLAAKQLNLQGT 1462
G + QG+I + L+ ++G+ A+ T ++QG
Sbjct 1354 INTSGNIETHQGDIVVRTGHLLNQREGFSAT----------------TTTRTNPSSIQGM 1397
Query 1463 GQN------QLLNNQSGQMLSMGGMNLNIDQINNKGKANTADADSHIMAAGELNITTQQL 1516
G LL + S + N + N G N + A + T + L
Sbjct 1398 GNALVDIPLSLLPDGSYGYFTREVENQHGTPCNGHGACNITMDTLYYYAPFADSATQRFL 1457
Query 1517 DNQN-TLNTDPANTSIQGIDANTLNVTSKVLNNQSGVIRSSADQNLNVQQALNNQSGQIS 1575
+QN T T N + + L+ ++ L N++ I ++ D L+ ++ L+NQS Q
Sbjct 1458 SSQNITTVTGADNPAGRIASGRNLSAEAERLENRASFILANGDIALSGRE-LSNQSWQTG 1516
Query 1576 SEKQ 1579
+E +
Sbjct 1517 TENE 1520
Score = 216 bits (549), Expect = 5e-58
Identities = 303/1217 (25%), Positives = 504/1217 (41%), Gaps = 208/1217 (17%)
Query 2086 ETDPAFADYKKWLSSDYMLDALGLDPALQQKRLGDGFYEQRLVQDQIANLTGYRFLEGFA 2145
ET P++ D K++L S Y LD LGL P + LGD ++ R V + + + TG R+L G
Sbjct 1724 ETAPSYTDEKQFLGSSYFLDRLGLKPEKDYRFLGDAVFDTRYVSNAVLSRTGSRYLNGLG 1783
Query 2146 NDDEQYKALMNNGITFAKLYGLRPGIALTAAQTAQLTSDIVWLVEQSVTLPDGTITKALV 2205
+D EQ + LM+N K GL G+ALTA Q AQL I+W +S T+ T+ +V
Sbjct 1784 SDTEQMRYLMDNAARQQKGLGLEFGVALTAEQIAQLDGSILWW--ESATINGQTV---MV 1838
Query 2206 PQVYVKVRVGDLKGDGTLLSGNSVNLKLDGDLINGATIAGREALQITADN-VQNLNGRI- 2263
P++Y+ L +G+++SGN+V L +G++I + L + + + NLN +
Sbjct 1839 PKLYLSPEDITLH-NGSVISGNNVQLAGGNITNSGSSINAQNGLSLDSTGYIDNLNAGLI 1897
Query 2264 -QGNQVAIETQKDLNNIGGQIIAKDAMALKVGGNLNIESTTRTSESKVGNFSSSITNVDR 2322
G + + D++NI I K V GN I + TR + G+ S R
Sbjct 1898 SAGGSLDLSAIGDISNISSVISGKTVQLESVSGN--ISNITRRQQWNAGSDS-------R 1948
Query 2323 VAGLYVGNGSTKQLDPNQAT--LMLNVAGNSSLKGVQINNSNSATVLNTTGN---VDLGT 2377
G+++ T + + T L L+ N + G + S+ T+ + GN +
Sbjct 1949 YGGVHLSGTDTGPVATIKGTDSLSLDAGKNIDITGATV--SSGGTLGMSAGNDINIAANL 2006
Query 2378 VSVGKQET--LKIDDKNGYQLKQQQDVGSQIKSAGSL-LINGQNITSKAVDLNSQQGDIQ 2434
+S K ++ DD + Q GS I + G+L + G N+ A +++ +
Sbjct 2007 ISGSKSQSGFWHTDDNSASSTTSQ---GSSISAGGNLAMAAGHNLDVTASSVSAGHSAL- 2062
Query 2435 LSAQKDIVLDNGLNQSTVSSQSQSKGSFGGKKSSTYDASSSTSIANQLNAGQNIIINSAQ 2494
LSA D+ L+ + +SK S G+ S S + + + AG N+++ + +
Sbjct 2063 LSAGNDLSLN---------AVRESKNSRNGRSES----HESHAAVSTVTAGDNLLLVAGR 2109
Query 2495 GNISATHLQAEAGNNIQIHAQQGNVTLLSAIDDKRESSTSSKKGVATYNNRQSGYIDQEV 2554
++++ A NN+ I + +V L++ +S TS KK RQ G
Sbjct 2110 -DVASQAAGVAAENNVVIRGGR-DVNLVAESAGAGDSYTSKKKKEINETVRQQG------ 2161
Query 2555 AQTTLKAGDTVDINAAKNIELQANDVQAGNSIYVGNTLMQRQADGSLKAADGSLMPENVT 2614
T + +G +NA ++I A+ V A +I V +V
Sbjct 2162 --TEIASGGDTTVNAGRDITAVASSVTATGNISVN-------------------AGRDVA 2200
Query 2615 LSTLATKDEQWDEQQKGYRGIVKDIVKATAVGLAGIEALAPGLKAPKITVSESTGKRTEQ 2674
L+T D + E +K G + K T+SE + R
Sbjct 2201 LTTATESDYHYLETKKKSGGFLS--------------------KKTTHTISEDSASR--- 2237
Query 2675 ISQTGSSLKADNVYVGSSGQTTLTSTDITAKNTILL--GQKVTLNAAEEQKIT--VESTS 2730
+ GS L + V V + T+ +D+ A + L G V + AA + + T
Sbjct 2238 --EAGSLLSGNRVTVNAGDNLTVEGSDVVADQDVSLAAGNHVDVLAATSTDTSWRFKETK 2295
Query 2731 KETVQGLG--------AKLNKDSIRLGGFVLEDASQSSKTTETTHKLGSINTENLKIQGV 2782
K + G G +K D G SQS+ T +T G+++ K +
Sbjct 2296 KSGLMGTGGIGFTIGSSKTTHDRREAG----TTQSQSASTIGST--AGNVSITAGKQAHI 2349
Query 2783 EGVDILG-QNITATGDTLIDHGRGDLNVGGYENKTTVEDKTHVETISTEVGVRNAYLDAA 2841
G D++ ++I+ TGD+++ V ++ TV++K + V +
Sbjct 2350 SGSDVIANRDISITGDSVV--------VDPGHDRRTVDEKFEQKKSGLTVALSGT---VG 2398
Query 2842 LALGAVKDAAEAVKQAKDQYSQAQRDYASGKITKEALDDSKANVAMATANLANAQIAVGS 2901
A+ +A+ K++ D +A + TK AL +A A A+ A G
Sbjct 2399 SAINNAVTSAQETKESSDSRLKALQ------ATKTALSGVQAGQAATMAS------ATGD 2446
Query 2902 AAATAAASSATYGFTIGANGERIETTNTTNTTQGKWQGSTLEL-NNLTL------KSENQ 2954
AT + S T T + ++ ++T + GSTL NNL++ + +N+
Sbjct 2447 PNATGVSLSLT---TQKSKSQQHSESDTVS-------GSTLNAGNNLSVVATGKNRGDNR 2496
Query 2955 -DVNVQGSRLTATGTTSFDGTKD--LNVTAGTEHSQQETSSKTNSQSVSYTYGGGGS--- 3008
D+ + GS+L G TS D D L+ A T+ + SS VS GG G+
Sbjct 2497 GDIVIAGSQLKVGGNTSLDAANDILLSGAANTQKTTGRNSSSGGGVGVSIGAGGNGAGIS 2556
Query 3009 ------ASIGKQTSTSESKSLTYVNSEVTLNKTEGR---LNSLNIKGGEVSIQDRGNLQV 3059
A+ G + + T +S T+ GR LN + G + I D G+
Sbjct 2557 VFAGVNAAKGSEKGNGTEWTETTTDSGKTVTINSGRDTVLNGAQVNGNRI-IADVGH--- 2612
Query 3060 NNIHVESLQDTAS----SSNSSRGGSIGGGYGSGSKNITASYNQSKGSSDSAWVNTTSKL 3115
++ + S QDT+ ++ + GGS G +GS I AS ++ K DS T
Sbjct 2613 -DLLISSQQDTSKYDSKQTSVAAGGSFTFGSMTGSGYIAASRDKMKSRFDSVAEQT---- 2667
Query 3116 LIGNAQNDANLDAMGVKNITNIGGVIANANKNADGSLTDHKNLNYTGNLELKDLQDHNNN 3175
G D D ++ G VIA+ + T KN TG L DL +
Sbjct 2668 --GMFAGDGGFDITVGRHTQLDGAVIAS-------TATPDKNHLDTGTLGFSDL-----H 2713
Query 3176 NSSGFNVS-TNIGIPQGGS---KAASTAPKGSTTIGLNSSGQETEQLTKATLGQGSVTNA 3231
N + + VS + I + GGS K P G + G +S E T+A + +G++T
Sbjct 2714 NEADYKVSHSGISLSGGGSFGDKFQGNMPGGMISAGGHSG--HAEGTTQAAVAEGTITIR 2771
Query 3232 TADTNRDINNTQEITRD 3248
D + N ++RD
Sbjct 2772 DRDNQK--QNLANLSRD 2786
Score = 179 bits (453), Expect = 8e-47
Identities = 324/1400 (23%), Positives = 541/1400 (39%), Gaps = 186/1400 (13%)
Query 543 NQGGQLNLGRVKIQGERFNNDQGQLTVKQAEIQTNSLSNQSGQLISNQKLNIQTQTANNQ 602
N+ N+G+ +G NN G+L Q G LI N N +
Sbjct 65 NRFTDYNVGK---EGLILNNATGKLN-----------PTQLGGLIQN---NPNLKAGGEA 107
Query 603 KGKIQSVDQLDLNVANGLNNIEGQIASGQQLNIQADQVNNQSGLIYSEQQGIELKANHAI 662
KG I V + ++ G + G+ A+ N + G + L +
Sbjct 108 KGIINEVTGGNRSLLQGYTEVAGKAANVMVANPYGITCD---GCGFINTPHATLTTGRPV 164
Query 663 NNTSGIIQA----KTQLNLASTQLDNTSGHIQAENIQQQHTTVNNTQGS----IVAGQSL 714
N G +QA + + + LD T A +I + T VN + + AG +
Sbjct 165 MNADGSLQALEVTEGSITINGAGLDGTRS--DAVSIIARATEVNAALHAKDLTVTAGANR 222
Query 715 ISTVDQFDNHQGLIDAKNIQLTHQVLNNSGSIYADQNIKITGQHILNTGSIAAGQNIQLN 774
I+ + +G D + + L G +YA + I +T S +G + L
Sbjct 223 ITADGRVSALKGEGDVPKVAVDTGAL---GGMYA-RRIHLT--------STESGVGVNLG 270
Query 775 TAKLQHEQAALIAAGLDRQGKLTSTGDLDITAEQTTLHGQSFAGQQLKVASKQQIDATNG 834
+ L +AG + G+ +T +L G + AG L V +
Sbjct 271 NLYARDGDIILSSAGKLVLKNSLAGGNTTVTGTDVSLSGDNKAGGNLSVTGTTGLTLNQP 330
Query 835 QLQAKNIDLASDAGDISTRAATVIAEQLSLKSHDLIDNQQGTLSAQQLNLTANRLDNTQG 894
+L + S +G I + A Q ++ S ++ GT++A + N+T ++T
Sbjct 331 RLVTDKNLVLSSSGQIVQNGGELTAGQNAMLSAQHLNQTSGTVNAAE-NVTLTTTNDTTL 389
Query 895 HILHTGQDQLDLNFSQSLNNQLGEIRSNAAELNIKTALLNNTEGQVVHAGTQQLNIQTAQ 954
L ++ S SLNN G + +KT +NT G V G L +
Sbjct 390 KGRSIAGKTLTVS-SGSLNN--GGTLVAGRDATVKTGTFSNT-GTVQGNG---LKVTATD 442
Query 955 LNGHLGHILSNGTLQLKAGTLDVSGGVTSADQITIQANVLNNAQGQLIQRGTSNPLNLTI 1014
L G I S TL + A +SG + D + + +G+L+ LT+
Sbjct 443 LTS-TGSIKSGSTLDISARNATLSGDAGAKDSARVTVSGTLENRGRLVSDDV-----LTL 496
Query 1015 QQQLNNQAGLIQSATATDIKAGSLNNQRGTLSSAQGQNLDVDVAGKLDNSQSGQIYAGNQ 1074
N +G + A A +L +++++ G NL +D A ++ +G+ AG
Sbjct 497 SATQINNSGTLSGAKELVASADTLTTTEKSVTNSDG-NLMLDSAS---STLAGETSAGGT 552
Query 1075 AHLQVGSIDNSHQGQINAQ------QNLQLTSQQQIN-----NQSGQIVANGDVQIQSQG 1123
++ S+ + Q QN QL Q N S ++ +G S
Sbjct 553 VSVKGNSLKTTTTAQTQGNSVSVDVQNAQLDGTQAARDILTLNASEKLTHSGKSSAPSLS 612
Query 1124 LNNSHGQMGSLQGGLSLNTGSDTLINQSGLIQAKKDIGIQAQRIDNQQGQITTQGQAELI 1183
L+ + G +LNT S TL N SGL+Q + + + QR+DNQQ T A+L
Sbjct 613 LSAPELTSSGVLVGSALNTQSQTLTN-SGLLQGEASLTVNTQRLDNQQNG-TLYSAADLT 670
Query 1184 SQAEIDNLEGAIAADLDVNIRSQGLNNNKGQISSAQG-NLTLNAGNGTLTNQAATIVSGK 1242
G I D + + + L+N I+ T G+G L A ++G
Sbjct 671 LDIPDIRNSGLITGDNGLMLNAVSLSNPGKIIADTLSVRATTLDGDGLLQGAGALALAGD 730
Query 1243 TLTLSANQLDNSNHGQINSQNNADISIVKDINNTSGVIAAKQQLILSSQGLNNTTGQIGT 1302
TL+ +HG+ + + D+S+ NT+G T GQ T
Sbjct 731 TLS-------QGSHGRWLTAD--DLSLRGKTLNTAGT----------------TQGQNIT 765
Query 1303 VQGNLHIDAGSQLLNNQQGRIQSGQDLNLNATGIDNTQGQISSKNQLQLDSREQLLNNRQ 1362
VQ + ++GS L +L +ATG + G I S+ L + +NR
Sbjct 766 VQADRWANSGSVLATG---------NLTASATGQLTSTGDIMSQGDTTL--KAATTDNRG 814
Query 1363 GTLSAENLTIDSGELNNDQGLIQAQQSIQIDTHQHNLSNTNSGAQGGI--LSQGNIQLNN 1420
LSA L++D L+N G +Q + Q+++ TNSG GI L+ ++
Sbjct 815 SLLSAGTLSLDGNSLDNS-GTVQGDH---VTIRQNSV--TNSGTLTGIAALTLAARMVSP 868
Query 1421 IQTLDNQQGYLASAQQLDLQANQVFNQNGTLLAAKQLNLQGTGQNQLLNNQSGQMLSMGG 1480
L N G L ++ L + A + N +G + AA L + TG+ L++ ++ S G
Sbjct 869 QPALMNNGGSLLTSGDLTITAGSLVN-SGAIQAADSLTARLTGE--LVSTAGSKVTSNGE 925
Query 1481 MNLNIDQINNKGKANTADADSHIMAAGELNITTQQLDNQNTLNTDPANTSIQGIDANTLN 1540
M L+ ++N G+ A L + L + I G+D TL
Sbjct 926 MALSALNLSNSGQ----------WIAKNLTLKANSLTSAG---------DITGVDTLTLT 966
Query 1541 VTSKVLNNQSGVIRSSADQNLNVQQALNNQSGQISSEKQLTLVGDQLEINNLNGQILAGT 1600
V + N +G + S+ L N+ GQ+ T+ QL NG L G
Sbjct 967 VNQTLNNQANGKLLSAGVLTLKADSVTND--GQLQGNAT-TITAGQLT----NGGHLQGE 1019
Query 1601 ALDLIAQSLSGD--GKLLSLGNAKLSLQNDYIHSSGAQLQANQDLSLSTKGNIINNGTIN 1658
L L A + G +L NA L++ + + G +Q +SL+ + N+ I
Sbjct 1020 TLTLAASGGVNNRFGGVLMSRNA-LNVSTATLSNQGT-IQGGGGVSLNVTDRLQNDSKIL 1077
Query 1659 AGNQLALNAANITNQQAGKIESHDTRLTAQNTLNNTGLINGDFTRLQAETLNNQGTGRIY 1718
+G+ L L A + N +G +++ L NT+N ++ ++ TLNN TG +
Sbjct 1078 SGSNLTLTAQVLANTGSGLVQAATLLLDVVNTVNGGRVLATGSADVKGTTLNN--TGTLQ 1135
Query 1719 GTTLAIQANTLNNQPDSTGTAPVIASRGDLHLGVQTLNNLSNPTDYTSQALIFSAGNLYL 1778
G L + +T +N GT+ LGV+ + L + T ++SAGNL
Sbjct 1136 GADLLVNYHTFSNSGTLLGTS---------GLGVKGSSLLQHGT-----GRLYSAGNL-- 1179
Query 1779 GAALDANDYATGQADVIHNESATIESLGDM----NLSAKQINNINKYFKTEQVEVSRKDG 1834
LDA D+ +GQ V+ T++ + + L+A + ++ V + D
Sbjct 1180 --LLDAQDF-SGQGQVVATGDVTLKLIAALTNHGTLAAGKTLSVTSQNAITNGGVMQGDA 1236
Query 1835 LEKYCDAWCTFDGNYYDGNPYEDWMRYYYSEITYETRTTESAPGQIKAGGHLDLNGAQVV 1894
+ T +G G + + R +APG ++AGG + LN +
Sbjct 1237 MVLGAGEAFTNNGMLTAGKG---------NSVFSAQRLFLNAPGSLQAGGDVSLNSRSDI 1287
Query 1895 NDKSQILAGGEL-KNEGGTI 1913
G L N GT+
Sbjct 1288 TISGFTGTAGSLTMNVAGTL 1307
Score = 177 bits (450), Expect = 2e-46
Identities = 333/1408 (24%), Positives = 554/1408 (39%), Gaps = 295/1408 (21%)
Query 662 INNTSGIIQAKTQLNLASTQLDNTSGHIQAENIQQQHTTVNNTQGSIVAGQSLISTVDQF 721
I +++G + K L +T + T + +N + +V T G +
Sbjct 280 ILSSAGKLVLKNSLAGGNTTVTGTDVSLSGDNKAGGNLSVTGTTGLTL------------ 327
Query 722 DNHQGLIDAKNIQLTH--QVLNNSGSIYADQNIKITGQHILNT-GSIAAGQNIQLNTAKL 778
N L+ KN+ L+ Q++ N G + A QN ++ QH+ T G++ A +N+ L T
Sbjct 328 -NQPRLVTDKNLVLSSSGQIVQNGGELTAGQNAMLSAQHLNQTSGTVNAAENVTLTTTND 386
Query 779 QHEQAALIA------------------AGLD---RQGKLTSTGD-----LDITAEQTTLH 812
+ IA AG D + G ++TG L +TA T
Sbjct 387 TTLKGRSIAGKTLTVSSGSLNNGGTLVAGRDATVKTGTFSNTGTVQGNGLKVTATDLTST 446
Query 813 GQSFAGQQLKVASKQQIDATNGQLQAKNIDLASDAGDISTRAATVIAEQLSLKSHDLIDN 872
G +G L ++++ +G AK+ + +G + R V + L+L + + N
Sbjct 447 GSIKSGSTLDISARNA--TLSGDAGAKDSARVTVSGTLENRGRLVSDDVLTLSATQI--N 502
Query 873 QQGTLS-AQQLNLTANRLDNTQGHILHT-GQDQLDLNFSQSLNNQLGEIRSNAAELNIKT 930
GTLS A++L +A+ L T+ + ++ G LD S ++ L S +++K
Sbjct 503 NSGTLSGAKELVASADTLTTTEKSVTNSDGNLMLD-----SASSTLAGETSAGGTVSVKG 557
Query 931 ALLNNTEGQVVHAGTQQLNIQTAQLNGHLGHILSNGTLQLKAGTLDVSGGVTSADQITIQ 990
L T + +++Q AQL+ G + L L A G +SA +++
Sbjct 558 NSLKTTTTAQTQGNSVSVDVQNAQLD---GTQAARDILTLNASEKLTHSGKSSAPSLSLS 614
Query 991 ANVLNNAQGQLIQRGTSNPLNLTIQQQLNNQAGLIQSATATDIKAGSLNNQRGTLSSAQG 1050
A L ++ G L+ L Q Q +GL+Q + + N QR
Sbjct 615 APELTSS-GVLVGSA------LNTQSQTLTNSGLLQGEASLTV-----NTQR-------- 654
Query 1051 QNLDVDVAGKLDNSQSGQIYAGNQAHLQVGSIDNSHQGQINAQQNLQLTSQQQINNQSGQ 1110
LDN Q+G +Y+ L + I NS G I L L + N G+
Sbjct 655 ----------LDNQQNGTLYSAADLTLDIPDIRNS--GLITGDNGLMLNAVSLSN--PGK 700
Query 1111 IVANGDVQIQSQGLNNSHGQMGSLQGGLSLNTGSDTLINQS-GLIQAKKDIGIQAQRIDN 1169
I+A+ + +++ L+ G LQG +L DTL S G D+ ++ + + N
Sbjct 701 IIAD-TLSVRATTLDGD----GLLQGAGALALAGDTLSQGSHGRWLTADDLSLRGKTL-N 754
Query 1170 QQGQITTQGQAELISQAEIDNLEGAIAADLDVNIRSQGLNNNKGQISSAQGNLTLNAGNG 1229
G TTQGQ + QA+ G++ A ++ + G + G I S QG+ TL A
Sbjct 755 TAG--TTQGQ-NITVQADRWANSGSVLATGNLTASATGQLTSTGDIMS-QGDTTLKAAT- 809
Query 1230 TLTNQAATIVSGKTLTLSANQLDNSNHGQINSQNNADISIVKDINNTSGVIAAKQQLILS 1289
T+ +++S TL+L N LDNS G + + ++I ++ SG + L L+
Sbjct 810 --TDNRGSLLSAGTLSLDGNSLDNS--GTVQGDH---VTIRQNSVTNSGTLTGIAALTLA 862
Query 1290 SQ------GLNNTTGQIGTVQGNLHIDAGSQLLNNQQGRIQSGQDLNLNATG--IDNTQG 1341
++ L N G + T G+L I AGS L+N+ G IQ+ L TG +
Sbjct 863 ARMVSPQPALMNNGGSLLT-SGDLTITAGS-LVNS--GAIQAADSLTARLTGELVSTAGS 918
Query 1342 QISSKNQLQLDSREQLLNNRQGTLSAENLTIDSGELNNDQGLIQAQQSIQIDTHQHNLSN 1401
+++S ++ L + L + G A+NLT+ + L +
Sbjct 919 KVTSNGEMALSA---LNLSNSGQWIAKNLTLKANSLTS---------------------- 953
Query 1402 TNSGAQGGILSQGNIQLNNIQTLDNQ-QGYLASAQQLDLQANQVFNQ-----NGTLLAAK 1455
G I + L QTL+NQ G L SA L L+A+ V N N T + A
Sbjct 954 -----AGDITGVDTLTLTVNQTLNNQANGKLLSAGVLTLKADSVTNDGQLQGNATTITAG 1008
Query 1456 QLNLQGTGQNQLLNNQSGQMLSMGGMNLNIDQINNKGKANTADADSHIMAAGELNITTQQ 1515
QL G Q + L + + GG+N + +M+ LN++T
Sbjct 1009 QLTNGGHLQGETLT-----LAASGGVNNRFGGV--------------LMSRNALNVSTAT 1049
Query 1516 LDNQNTLN---------TDPANTSIQGIDANTLNVTSKVLNNQSGVIRSSADQNLNVQQA 1566
L NQ T+ TD + + + L +T++VL N + +A L+V
Sbjct 1050 LSNQGTIQGGGGVSLNVTDRLQNDSKILSGSNLTLTAQVLANTGSGLVQAATLLLDVVNT 1109
Query 1567 LNNQSGQISSEKQL---------TLVGDQLEIN----NLNGQILAGTALDLIAQSL--SG 1611
+N + + TL G L +N + +G +L + L + SL G
Sbjct 1110 VNGGRVLATGSADVKGTTLNNTGTLQGADLLVNYHTFSNSGTLLGTSGLGVKGSSLLQHG 1169
Query 1612 DGKLLSLGNAKLSLQNDYIHSSGAQLQANQDLSLSTKGNIINNGTINAGNQLALNAANIT 1671
G+L S GN L Q+ S Q+ A D++L + N+GT+ AG L++
Sbjct 1170 TGRLYSAGNLLLDAQD---FSGQGQVVATGDVTLKLIAALTNHGTLAAGKTLSV------ 1220
Query 1672 NQQAGKIESHDTRLTAQNTLNNTGLINGDFTRLQA-ETLNNQG---TGRIYGTTLAIQAN 1727
T+QN + N G++ GD L A E N G G+ G ++
Sbjct 1221 --------------TSQNAITNGGVMQGDAMVLGAGEAFTNNGMLTAGK--GNSVFSAQR 1264
Query 1728 TLNNQPDS--TGTAPVIASRGDLHLG--VQTLNNLSNPTDYT--SQALIFSAGNLYL--- 1778
N P S G + SR D+ + T +L+ T + ALI++ NL L
Sbjct 1265 LFLNAPGSLQAGGDVSLNSRSDITISGFTGTAGSLTMNVAGTLLNSALIYAGNNLKLFTD 1324
Query 1779 -----------GAALDANDYATGQADV-IHNESATIES-LGDMNLSAKQINNINKYFKTE 1825
G +L A+G A+ I N S IE+ GD+ + + N + F
Sbjct 1325 RLHNQHGDILAGNSLWVQKDASGGANTEIINTSGNIETHQGDIVVRTGHLLNQREGFSAT 1384
Query 1826 QVEVSRKDGLEKYCDAWCTF------DGNY----------------------------YD 1851
+ ++ +A DG+Y Y
Sbjct 1385 TTTRTNPSSIQGMGNALVDIPLSLLPDGSYGYFTREVENQHGTPCNGHGACNITMDTLYY 1444
Query 1852 GNPYED--WMRYYYSEITYETRTTESAPGQIKAGGHLDLNGAQVVNDKSQILAGGELKNE 1909
P+ D R+ S+ ++ G+I +G +L ++ N S ILA G++
Sbjct 1445 YAPFADSATQRFLSSQNITTVTGADNPAGRIASGRNLSAEAERLENRASFILANGDIALS 1504
Query 1910 GGTIDSGTQIAGIRKIVNTGTQVKYWKY 1937
G + + + TGT+ +Y Y
Sbjct 1505 GRELSNQSW--------QTGTENEYLVY 1524
Score = 130 bits (327), Expect = 4e-32
Identities = 232/968 (24%), Positives = 380/968 (39%), Gaps = 174/968 (18%)
Query 1024 LIQSATATDIKAGSLNNQRGT--LSSAQGQNLDVDVAGK------LDNSQSGQIYAGNQA 1075
L + + + G+L + G LSSA L +AG D S SG AG
Sbjct 258 LTSTESGVGVNLGNLYARDGDIILSSAGKLVLKNSLAGGNTTVTGTDVSLSGDNKAGGNL 317
Query 1076 HLQVGSIDNSHQGQINAQQNLQLTSQQQINNQSGQIVANGDVQIQSQGLNNSHGQMGSLQ 1135
+ + +Q ++ +NL L+S QI G++ A + + +Q LN + G + + +
Sbjct 318 SVTGTTGLTLNQPRLVTDKNLVLSSSGQIVQNGGELTAGQNAMLSAQHLNQTSGTVNAAE 377
Query 1136 GGLSLNTGSDTLI-----------------NQSGLIQAKKDIGIQAQRIDNQQGQITTQG 1178
++L T +DT + N G + A +D ++ N T QG
Sbjct 378 N-VTLTTTNDTTLKGRSIAGKTLTVSSGSLNNGGTLVAGRDATVKTGTFSNTG---TVQG 433
Query 1179 QAELISQAEIDNLEGAI--AADLDVNIRSQGLNNNKGQISSAQGNLTLNAGNGTLTNQAA 1236
++ ++ + G+I + LD++ R+ L+ + G SA+ ++ GTL N+
Sbjct 434 NGLKVTATDLTST-GSIKSGSTLDISARNATLSGDAGAKDSARVTVS-----GTLENRGR 487
Query 1237 TIVSGKTLTLSANQLDNSNHGQINSQNNADISIVKDINNTSGVIAAKQQLILSSQGLNNT 1296
+VS LTLSA Q++NS G ++ ++L+ S+ L T
Sbjct 488 -LVSDDVLTLSATQINNS-----------------------GTLSGAKELVASADTLTTT 523
Query 1297 TGQIGTVQGNLHIDAGSQLLNNQQGRIQSGQDLNLNATGIDNTQGQISSKNQLQLDSREQ 1356
+ GNL +D+ S L G +G +++ + T + N + +D +
Sbjct 524 EKSVTNSDGNLMLDSASSTL---AGETSAGGTVSVKGNSLKTTTTAQTQGNSVSVDVQNA 580
Query 1357 LLNNRQGTLSAENLTIDSGELNNDQGLIQAQQSIQIDTHQHNLSNTNSGAQ-GGILSQGN 1415
L+ Q + + LT+++ E G A S+ + + T+SG G L+ +
Sbjct 581 QLDGTQA--ARDILTLNASEKLTHSGKSSAP-SLSLSAPEL----TSSGVLVGSALNTQS 633
Query 1416 IQLNNIQTLDNQQGYLASAQQLDLQANQVFNQNGTLLAAKQLNLQGTGQNQLLNNQSGQM 1475
L N L + + Q+LD Q QNGTL +A L L SG +
Sbjct 634 QTLTNSGLLQGEASLTVNTQRLDNQ------QNGTLYSAADLTLDIPDIRN-----SGLI 682
Query 1476 LSMGGMNLNIDQINNKGK---------ANTADADSHIMAAGELNI---TTQQLDNQNTLN 1523
G+ LN ++N GK A T D D + AG L + T Q + L
Sbjct 683 TGDNGLMLNAVSLSNPGKIIADTLSVRATTLDGDGLLQGAGALALAGDTLSQGSHGRWLT 742
Query 1524 TDPANTSIQGIDANTLNVTSKVLNNQSGVIRSSADQNLNVQQALNNQSGQISSEKQLTLV 1583
D + S++G NT T Q I AD+ N L + S+ QLT
Sbjct 743 AD--DLSLRGKTLNTAGTT------QGQNITVQADRWANSGSVLATGNLTASATGQLTST 794
Query 1584 GDQLEINNLNGQILAGTALDLIAQSLSGDGKLLSLGNAKLSLQNDYIHSSGAQLQANQDL 1643
GD I++ L A + G LLS G LSL + + +SG D
Sbjct 795 GD----------IMSQGDTTLKAATTDNRGSLLSAGT--LSLDGNSLDNSGT---VQGDH 839
Query 1644 SLSTKGNIINNGTINAGNQLALNAANITNQQA------GKIESHDTRLTAQNTLNNTGLI 1697
+ ++ N+GT+ L L A ++ Q A + S D +TA + +N+ +
Sbjct 840 VTIRQNSVTNSGTLTGIAALTLAARMVSPQPALMNNGGSLLTSGDLTITAGSLVNSGAIQ 899
Query 1698 NGDF--TRLQAETLNNQGTGRIYGTTLAIQANTLNNQ-----PDSTGTAPVIASRGDLHL 1750
D RL E ++ G+ +A+ A L+N + T A + S GD+
Sbjct 900 AADSLTARLTGELVSTAGSKVTSNGEMALSALNLSNSGQWIAKNLTLKANSLTSAGDI-T 958
Query 1751 GVQTLNNLSNPT-DYTSQALIFSAGNLYLGAALDANDYATGQADVIHNESATIESLGDMN 1809
GV TL N T + + + SAG L L A ND GQ + + TI
Sbjct 959 GVDTLTLTVNQTLNNQANGKLLSAGVLTLKADSVTND---GQ---LQGNATTI------- 1005
Query 1810 LSAKQINNINKYFKTEQVEVSRKDGLEKYCDAWCTFDGNYYDGNPYEDWMRYYYSEITYE 1869
+A Q+ N + + E + ++ G+ F G N
Sbjct 1006 -TAGQLTN-GGHLQGETLTLAASGGVNN------RFGGVLMSRNALN------------V 1045
Query 1870 TRTTESAPGQIKAGGHLDLNGAQVVNDKSQILAGGE-------LKNEG-GTIDSGTQIAG 1921
+ T S G I+ GG + LN + + S+IL+G L N G G + + T +
Sbjct 1046 STATLSNQGTIQGGGGVSLNVTDRLQNDSKILSGSNLTLTAQVLANTGSGLVQAATLLLD 1105
Query 1922 IRKIVNTG 1929
+ VN G
Sbjct 1106 VVNTVNGG 1113
Score = 76.6 bits (187), Expect = 8e-16
Identities = 370/1917 (19%), Positives = 672/1917 (35%), Gaps = 354/1917 (18%)
Query 79 TLPLNTIADSQIIADKGAPT------SQQPTILNSSNGVTQVNIQTPSAGGVSRNTYSQF 132
T+ N++ +S + A T S QP ++N+ + T +AG + +
Sbjct 841 TIRQNSVTNSGTLTGIAALTLAARMVSPQPALMNNGGSLLTSGDLTITAGSLVNS----- 895
Query 133 DVGQEGAILNNARNNTQTQLGGWI---QGNPWLAKGEAKVILNEVNSSNPSQLKGYIEVA 189
GAI A ++ +L G + G+ + GE + L+ +N SN Q
Sbjct 896 -----GAI--QAADSLTARLTGELVSTAGSKVTSNGE--MALSALNLSNSGQWI------ 940
Query 190 GKQAQVVIANPSGLVCDGCGVINADRFTLTTGQAVMNQ--GYLESFRV---REGQITIQG 244
A+ + + L G + D TLT Q + NQ G L S V + +T G
Sbjct 941 ---AKNLTLKANSLTSAG-DITGVDTLTLTVNQTLNNQANGKLLSAGVLTLKADSVTNDG 996
Query 245 KGLNGSLTPFT----------DVYARALQVNAGLYAKELNVVLGQNDINVNDPTTSNVSP 294
+ L G+ T T L + G+ + V++ +N +NV+ T SN
Sbjct 997 Q-LQGNATTITAGQLTNGGHLQGETLTLAASGGVNNRFGGVLMSRNALNVSTATLSNQGT 1055
Query 295 IQ--------------------------------SNTSANNKPQFALDVGQLGGMYAGKI 322
IQ +NT + L + + + G++
Sbjct 1056 IQGGGGVSLNVTDRLQNDSKILSGSNLTLTAQVLANTGSGLVQAATLLLDVVNTVNGGRV 1115
Query 323 FLVGTE--QGVGVRNAGSMNSTQSTL---TLNANGDLTNTGNL--------------IAN 363
G+ +G + N G++ + T + +G L T L + +
Sbjct 1116 LATGSADVKGTTLNNTGTLQGADLLVNYHTFSNSGTLLGTSGLGVKGSSLLQHGTGRLYS 1175
Query 364 QGQLQLNAENIKNTGNISSATSQVSLHS-QNLDNSGLISSADELNIQQQGHVGNRGTLNA 422
G L L+A++ G + AT V+L L N G +++ L++ Q + N G +
Sbjct 1176 AGNLLLDAQDFSGQGQVV-ATGDVTLKLIAALTNHGTLAAGKTLSVTSQNAITNGGVMQG 1234
Query 423 ARIVVDAGSLANSGSIEQTG-------AQALDLKAGSMSNIGGKIGIAKTSSTGGNGSES 475
+V+ AG + + G AQ L L A GG + + S +G
Sbjct 1235 DAMVLGAGEAFTNNGMLTAGKGNSVFSAQRLFLNAPGSLQAGGDVSLNSRSDITISGFTG 1294
Query 476 GGGSQPVEPNNAAQDGGSLEVVNTDSTPTTPKTYETGYIHVRDQLNNDQGAIVAQGGIDL 535
GS + + + N T D+L+N G I+A + +
Sbjct 1295 TAGSLTMNVAGTLLNSALIYAGNNLKLFT-------------DRLHNQHGDILAGNSLWV 1341
Query 536 E------SNNGLDNQGGQLNLGRVKI---QGERFNNDQGQLTVKQAEIQTNSLSNQSGQL 586
+ +N + N G + + I G N +G +S+ L
Sbjct 1342 QKDASGGANTEIINTSGNIETHQGDIVVRTGHLLNQREGFSATTTTRTNPSSIQGMGNAL 1401
Query 587 IS-------NQKLNIQTQTANNQKGK---------------------IQSVDQLDLNVAN 618
+ + T+ NQ G S Q L+ N
Sbjct 1402 VDIPLSLLPDGSYGYFTREVENQHGTPCNGHGACNITMDTLYYYAPFADSATQRFLSSQN 1461
Query 619 -----GLNNIEGQIASGQQLNIQADQVNNQSGLIYSEQQGIELKANHAINNT-------- 665
G +N G+IASG+ L+ +A+++ N++ I + I L N +
Sbjct 1462 ITTVTGADNPAGRIASGRNLSAEAERLENRASFILANGD-IALSGRELSNQSWQTGTENE 1520
Query 666 -------------SGIIQAKTQLNLASTQLDNTSGHIQAENIQQQHTTVNNTQGSIVAGQ 712
S + +L L S + +N + + ++ +T I AG
Sbjct 1521 YLVYRYDPKTFYGSYATGSLDKLPLLSPEFENNTIRFSLDGREKDYTPGKTYYSVIQAGG 1580
Query 713 SLISTVDQFDNHQGLIDAKNIQLTHQVLNNSGSIYADQNIKITGQHILNTGSIAAGQNIQ 772
+ + T + N + + +A + +LNT S G +
Sbjct 1581 DV-----------------KTRFTSSINNGTTTAHAGSVSPVVSAPVLNTLSQQTGGDSL 1623
Query 773 LNTAKLQHEQAALIAAGLDRQGKLTSTGDLDITAEQTTLHGQSFAGQQLKVASKQ----- 827
TA Q+E + + Q G L A + L GQ+ + S
Sbjct 1624 TQTALQQYEPVVVGSP----QWHDELAGALKNIAGGSPLTGQTGISDDWPLPSGNNGYLV 1679
Query 828 -QIDATNGQLQAKNIDLASDAGDISTRAATVIAEQLSLK--------SHDLIDNQQ---G 875
D + L N L G + + + E L K + D +Q
Sbjct 1680 PSTDPDSPYLITVNPKL-DGLGQVDSHLFAGLYELLGAKPGQAPRETAPSYTDEKQFLGS 1738
Query 876 TLSAQQLNLTANRLDNTQGHILHTGQDQLDLNFSQSLNNQLGEIRSNAAELNIKTALLNN 935
+ +L L + G + + + S++ + L + S+ ++ L++N
Sbjct 1739 SYFLDRLGLKPEKDYRFLGDAVFDTRYVSNAVLSRTGSRYLNGLGSDTEQMRY---LMDN 1795
Query 936 TEGQVVHAGTQQLNIQTAQLNGHL-GHILSNGTLQLKAGTLDVSGGVTSADQIT------ 988
Q G + TA+ L G IL + + T+ V S + IT
Sbjct 1796 AARQQKGLGLEFGVALTAEQIAQLDGSILWWESATINGQTVMVPKLYLSPEDITLHNGSV 1855
Query 989 IQANVLNNAQGQLIQRGTS----NPLNLTIQQQLNN-QAGLIQSATATDIKA-GSLNNQR 1042
I N + A G + G+S N L+L ++N AGLI + + D+ A G ++N
Sbjct 1856 ISGNNVQLAGGNITNSGSSINAQNGLSLDSTGYIDNLNAGLISAGGSLDLSAIGDISNIS 1915
Query 1043 GTLSSAQGQNLDVD-VAGKLDN------------SQSGQIYAGNQAHLQVGSIDNSHQGQ 1089
+S G+ + ++ V+G + N S+ G ++ V +I +
Sbjct 1916 SVIS---GKTVQLESVSGNISNITRRQQWNAGSDSRYGGVHLSGTDTGPVATIKGTDSLS 1972
Query 1090 INAQQNLQLTSQQQINNQSGQIVANGDVQIQSQGLNNSHGQMGSLQGGLSLNTGSDTLIN 1149
++A +N+ +T + + + A D+ I + ++ S Q G N+ S T +
Sbjct 1973 LDAGKNIDITGATVSSGGTLGMSAGNDINIAANLISGSKSQSGFWH--TDDNSASST-TS 2029
Query 1150 QSGLIQAKKDIGIQAQRIDNQQGQITTQGQAELISQAEIDNLEGAIAADLDVNIRSQGLN 1209
Q I A ++ + A + + G + L+S DL +N + N
Sbjct 2030 QGSSISAGGNLAMAAGHNLDVTASSVSAGHSALLSAGN----------DLSLNAVRESKN 2079
Query 1210 NNKGQISSAQGNLTLNAGNGTLTNQAATIVSGKTLTLSANQLDNSNHGQINSQNNADISI 1269
+ G+ S + + + +T+ +G L L A + S + ++NN I
Sbjct 2080 SRNGRSESHESHAAV-----------STVTAGDNLLLVAGRDVASQAAGVAAENNVVIRG 2128
Query 1270 VKDINNTS-GVIAAKQQLILSSQGLNNTTGQIGT---VQGNLHIDAG-------SQLLNN 1318
+D+N + A + +N T Q GT G+ ++AG S +
Sbjct 2129 GRDVNLVAESAGAGDSYTSKKKKEINETVRQQGTEIASGGDTTVNAGRDITAVASSVTAT 2188
Query 1319 QQGRIQSGQDLNL-NATGID--------NTQGQISSKNQLQLD----SRE--QLLNNRQG 1363
+ +G+D+ L AT D + G +S K + SRE LL+ +
Sbjct 2189 GNISVNAGRDVALTTATESDYHYLETKKKSGGFLSKKTTHTISEDSASREAGSLLSGNRV 2248
Query 1364 TLSA-ENLTIDSGELNNDQGLIQAQQSIQIDTHQHNLSNTNSGA--------QGGILSQG 1414
T++A +NLT++ ++ DQ + S+ H L+ T++ + G++ G
Sbjct 2249 TVNAGDNLTVEGSDVVADQDV-----SLAAGNHVDVLAATSTDTSWRFKETKKSGLMGTG 2303
Query 1415 NIQL---NNIQTLDNQQGYLASAQQLDLQANQVFNQNGTLLAAKQLNLQGT---GQNQLL 1468
I ++ T D ++ +Q + N ++ A KQ ++ G+ +
Sbjct 2304 GIGFTIGSSKTTHDRREAGTTQSQSASTIGSTA--GNVSITAGKQAHISGSDVIANRDIS 2361
Query 1469 NNQSGQMLSMGGMNLNIDQINNKGKANTADADSHIMAAGELNITTQQLDNQNTLNT---- 1524
++ G +D+ + K+ A S + + N T + + + ++
Sbjct 2362 ITGDSVVVDPGHDRRTVDEKFEQKKSGLTVALSGTVGSAINNAVTSAQETKESSDSRLKA 2421
Query 1525 -DPANTSIQGIDANTLNVTSKVLN--NQSGVIRSSADQNLNVQQALNNQSGQISSEKQLT 1581
T++ G+ A + N +GV S Q QQ +++S +S
Sbjct 2422 LQATKTALSGVQAGQAATMASATGDPNATGVSLSLTTQKSKSQQ--HSESDTVS------ 2473
Query 1582 LVGDQLEI-NNLNGQILAGTALDLIAQSLSGDGKLLSLGNAKLSLQNDYIHSSGAQLQAN 1640
G L NNL+ D + +L GN L ND + S A Q
Sbjct 2474 --GSTLNAGNNLSVVATGKNRGDNRGDIVIAGSQLKVGGNTSLDAANDILLSGAANTQKT 2531
Query 1641 QDLSLSTKGNI-INNGTINAGNQLALNAANITNQQAGKIESHDTRLTAQNT-LNNTGLIN 1698
+ S+ G + ++ G GN ++ N G + + T T T T IN
Sbjct 2532 TGRNSSSGGGVGVSIGA--GGNGAGISVFAGVNAAKGSEKGNGTEWTETTTDSGKTVTIN 2589
Query 1699 -GDFTRLQAETLNNQGTGRIYGTTLAIQANTLNNQPDSTGTAPVIASRGDLHLGVQT 1754
G T L +N G L I + ++ DS T+ +A+ G G T
Sbjct 2590 SGRDTVLNGAQVNGNRIIADVGHDLLISSQQDTSKYDSKQTS--VAAGGSFTFGSMT 2644
Score = 72.4 bits (176), Expect = 2e-14
Identities = 225/1132 (20%), Positives = 421/1132 (37%), Gaps = 174/1132 (15%)
Query 2210 VKVRVGDLKG-DGTLLSGNSVNLKLDGDLINGATIAGREALQITADNVQNLNGRIQG--- 2265
V V +G+L DG ++ ++ L L L G T + ++ DN N + G
Sbjct 265 VGVNLGNLYARDGDIILSSAGKLVLKNSLAGGNTTVTGTDVSLSGDNKAGGNLSVTGTTG 324
Query 2266 ---NQVAIETQKDLNNIGGQIIAKDAMALKVGGNLNIESTTRTSESKVGNFSSSITNVDR 2322
NQ + T K+L +++ ++ GG L S + S ++ +
Sbjct 325 LTLNQPRLVTDKNL------VLSSSGQIVQNGGELTAGQNAMLSAQHLNQTSGTVNAAEN 378
Query 2323 VAGLYVGNGSTKQLDPNQATLMLNVAGNSSLKGVQINNSNSATV----LNTTGNVD---- 2374
V L N +T + + A L V+ S G + ATV + TG V
Sbjct 379 VT-LTTTNDTTLK-GRSIAGKTLTVSSGSLNNGGTLVAGRDATVKTGTFSNTGTVQGNGL 436
Query 2375 -------LGTVSVGKQETLKIDDKNGYQLKQQQDVG----SQIKSAGSLLINGQNITSKA 2423
T S+ TL I +N D G +++ +G+L G+ ++
Sbjct 437 KVTATDLTSTGSIKSGSTLDISARNA---TLSGDAGAKDSARVTVSGTLENRGRLVSDDV 493
Query 2424 VDLNSQQ--GDIQLSAQKDIVLDNGLNQSTVSSQSQSKGSFGGKKSSTYDASSSTSIANQ 2481
+ L++ Q LS K++V +T S + S G+ D++SST +A +
Sbjct 494 LTLSATQINNSGTLSGAKELVASADTLTTTEKSVTNSDGNL------MLDSASST-LAGE 546
Query 2482 LNAGQNIIINSAQGNISATHLQAEA-GNNIQIHAQQGNVTLLSAIDDKRESSTSSKKGVA 2540
+AG + S +GN T A+ GN++ + Q + T + + +
Sbjct 547 TSAGGTV---SVKGNSLKTTTTAQTQGNSVSVDVQNAQL-----------DGTQAARDIL 592
Query 2541 TYNNRQSGYIDQEVAQTTLKAGDTVDINAAKNIELQANDVQAGNSIYVGNTLMQRQADGS 2600
T N +++ + + ++ ++A EL ++ V G+++ NT Q +
Sbjct 593 TLN------ASEKLTHSGKSSAPSLSLSAP---ELTSSGVLVGSAL---NTQSQTLTNSG 640
Query 2601 LKAADGSLMPENVTLSTLATKDEQWDEQQKGYRGIVKDIV--------KATAVGLAGIEA 2652
L + SL T++T ++ D QQ G D+ G G+
Sbjct 641 LLQGEASL-----TVNT-----QRLDNQQNGTLYSAADLTLDIPDIRNSGLITGDNGLML 690
Query 2653 LAPGLKAPKITVSESTGKRTEQISQTG-------SSLKADNVYVGSSGQTTLTSTDITAK 2705
A L P ++++ R + G +L D + GS G+ LT+ D++ +
Sbjct 691 NAVSLSNPGKIIADTLSVRATTLDGDGLLQGAGALALAGDTLSQGSHGR-WLTADDLSLR 749
Query 2706 NTIL------LGQKVTLNAAE-EQKITVESTSKETVQGLGAKLNKDSIRLGGFVLEDASQ 2758
L GQ +T+ A +V +T T G + I G D +
Sbjct 750 GKTLNTAGTTQGQNITVQADRWANSGSVLATGNLTASATGQLTSTGDIMSQG----DTTL 805
Query 2759 SSKTTETTHKLGSINTENLKIQGVEGVDILGQNITATGDTLIDHGRGDLNVGGYENKTTV 2818
+ TT+ L S T +L G ++ +G DH + N T+
Sbjct 806 KAATTDNRGSLLSAGTLSLD----------GNSLDNSGTVQGDH--VTIRQNSVTNSGTL 853
Query 2819 EDKTHVETISTEVGVRNAYLDAALALGAVKDAAEAVKQAKDQYSQAQRDYASGKITKEAL 2878
+ + V + A ++ +L D + + D + ++T E +
Sbjct 854 TGIAALTLAARMVSPQPALMNNGGSLLTSGDLTITAGSLVNSGAIQAADSLTARLTGELV 913
Query 2879 D------DSKANVAMATANLANAQIAVGSAAATAAASSATYGFTIGANGERIETTNTTNT 2932
S +A++ NL+N+ + A S + G G + + T N
Sbjct 914 STAGSKVTSNGEMALSALNLSNSGQWIAKNLTLKANSLTSAGDITGVDTLTLTVNQTLN- 972
Query 2933 TQGKWQGSTLELNNLTLKSEN--QDVNVQGSRLTATGTTSFDGTKDLNVTAGTEHSQQET 2990
+ G L LTLK+++ D +QG+ T T +G H Q ET
Sbjct 973 --NQANGKLLSAGVLTLKADSVTNDGQLQGNATTITAGQLTNG----------GHLQGET 1020
Query 2991 SSKTNSQSVSYTYGG--GGSASIGKQTSTSESKSLTYVNSEVTLNKTEGRLNSLNI-KGG 3047
+ S V+ +GG ++ T+T ++ V+LN T+ N I G
Sbjct 1021 LTLAASGGVNNRFGGVLMSRNALNVSTATLSNQGTIQGGGGVSLNVTDRLQNDSKILSGS 1080
Query 3048 EVSIQDRGNLQVNNIHVESLQDTASSSNSSRGGSIGGGYGSGSKNITASYNQSKGSSDSA 3107
+++ + + V++ N+ GG + +GS ++ + + G+ A
Sbjct 1081 NLTLTAQVLANTGSGLVQAATLLLDVVNTVNGGRV---LATGSADVKGTTLNNTGTLQGA 1137
Query 3108 --WVN----TTSKLLIGNA---QNDANLDAMGVKNITNIGGVIANANKNADGSLTDHKNL 3158
VN + S L+G + ++L G + + G ++ +A + +
Sbjct 1138 DLLVNYHTFSNSGTLLGTSGLGVKGSSLLQHGTGRLYSAGNLLLDAQ-----DFSGQGQV 1192
Query 3159 NYTGNLELKDLQDHNNNNS---------SGFNVSTNIGIPQGGSKAASTAPKGSTTIGLN 3209
TG++ LK + N+ + + N TN G+ QG + A + T G+
Sbjct 1193 VATGDVTLKLIAALTNHGTLAAGKTLSVTSQNAITNGGVMQGDAMVLG-AGEAFTNNGML 1251
Query 3210 SSGQETEQLTKATLGQGSVTNATADTNRDINNTQEITRDQTTGMLNGSVTVD 3261
++G+ + L + + A + +N+ +IT TG GS+T++
Sbjct 1252 TAGKGNSVFSAQRLFLNAPGSLQAGGDVSLNSRSDITISGFTGTA-GSLTMN 1302
Score = 71.2 bits (173), Expect = 4e-14
Identities = 238/1143 (21%), Positives = 410/1143 (36%), Gaps = 148/1143 (13%)
Query 2217 LKGDGTLLSGNSVNLKLDGDLINGATIAGREALQITADNVQNLNGRIQGNQVAIETQKDL 2276
++ G L +G + L T+ E + +T N L GR + + L
Sbjct 347 VQNGGELTAGQNAMLSAQHLNQTSGTVNAAENVTLTTTNDTTLKGRSIAGKTLTVSSGSL 406
Query 2277 NNIGGQIIAKDAMALKVGGNLNIESTTRTSESKVGNFSSSITNVDRVAGLYVGNGSTKQL 2336
NN GG ++A G + +++ T ++ V +T D + + +GST +
Sbjct 407 NN-GGTLVA--------GRDATVKTGTFSNTGTVQGNGLKVTATDLTSTGSIKSGSTLDI 457
Query 2337 DPNQATLM----------LNVAGNSSLKGVQINN---SNSATVLNTTGNVDLGTVSVGKQ 2383
ATL + V+G +G +++ + SAT +N +G + V
Sbjct 458 SARNATLSGDAGAKDSARVTVSGTLENRGRLVSDDVLTLSATQINNSGTLSGAKELVASA 517
Query 2384 ETLKIDDK-------NGYQLKQQQDVGSQIKSAGSLLINGQNI---TSKAVDLNSQQGDI 2433
+TL +K N + + + G++ + G ++ T+ NS D+
Sbjct 518 DTLTTTEKSVTNSDGNLMLDSASSTLAGETSAGGTVSVKGNSLKTTTTAQTQGNSVSVDV 577
Query 2434 Q------LSAQKDIVLDNGLNQSTVSSQSQSKGSFGGKKSSTYDASSSTSIANQLNAGQN 2487
Q A +DI+ N + T S +S + S+ SS + + LN
Sbjct 578 QNAQLDGTQAARDILTLNASEKLTHSGKSSAPSL---SLSAPELTSSGVLVGSALNTQSQ 634
Query 2488 IIINSA--QGNISATHLQAEAGNNIQIHAQQGNVTLLSAIDDKRESSTSSKKGVATYNNR 2545
+ NS QG S T N Q Q N TL SA D + G+ T +N
Sbjct 635 TLTNSGLLQGEASLTV-------NTQRLDNQQNGTLYSAADLTLDIPDIRNSGLITGDN- 686
Query 2546 QSGYIDQEVAQTTLKA--GDTVDINAAKNIELQANDVQAGNSIYVGNTLMQRQADGSLKA 2603
G + V+ + DT+ + A ++ AG G+TL Q L A
Sbjct 687 --GLMLNAVSLSNPGKIIADTLSVRAT-TLDGDGLLQGAGALALAGDTLSQGSHGRWLTA 743
Query 2604 ADGSLMPENVTLSTLATKDEQ-----WDEQQKGYRGIVKDIVKATAVG--LAGIEALAPG 2656
D SL + TL+T T Q D + + A+A G + + ++ G
Sbjct 744 DDLSLRGK--TLNTAGTTQGQNITVQADRWANSGSVLATGNLTASATGQLTSTGDIMSQG 801
Query 2657 LKAPKITVSESTGKRTEQ--ISQTGSSLKADNVYVGSSGQTTLTSTDITAKNTILLGQKV 2714
K +++ G +S G+SL DN T+ +T T+ +
Sbjct 802 DTTLKAATTDNRGSLLSAGTLSLDGNSL--DNSGTVQGDHVTIRQNSVTNSGTLTGIAAL 859
Query 2715 TLNAAEEQKITVESTSKETVQGLGAKLNKDSIRL--GGFVLEDASQS--SKTTETTHKLG 2770
TL A + S + G+ L + + G V A Q+ S T T +L
Sbjct 860 TLAAR------MVSPQPALMNNGGSLLTSGDLTITAGSLVNSGAIQAADSLTARLTGEL- 912
Query 2771 SINTENLKIQGVEGVDILGQNITATGDTLIDHGRGDLNVGGYENKTTVEDKTHVETISTE 2830
++T K+ + + N++ +G + + N + T+ D T V+T++
Sbjct 913 -VSTAGSKVTSNGEMALSALNLSNSGQWIAKNLTLKAN-----SLTSAGDITGVDTLTLT 966
Query 2831 VG--VRNAYLDAALALGAVKDAAEAVKQAKDQYSQAQRDYASGKITKEALDDSKANVAMA 2888
V + N L+ G + A++V A +G++T + A
Sbjct 967 VNQTLNNQANGKLLSAGVLTLKADSVTNDGQLQGNATT-ITAGQLTNGGHLQGETLTLAA 1025
Query 2889 TANLAN---AQIAVGSAAATAAASSATYGFTIGANGERIETTNTTNTTQGKWQGSTLELN 2945
+ + N + +A + A+ + G G G + T+ GS L L
Sbjct 1026 SGGVNNRFGGVLMSRNALNVSTATLSNQGTIQGGGGVSLNVTDRLQNDSKILSGSNLTLT 1085
Query 2946 NLTLKSENQDV------------NVQGSRLTATGTTSFDGTKDLNVTAGTEHSQQETSSK 2993
L + + V G R+ ATG+ GT LN T + + +
Sbjct 1086 AQVLANTGSGLVQAATLLLDVVNTVNGGRVLATGSADVKGTT-LNNTGTLQGADLLVNYH 1144
Query 2994 T--NSQSVSYTYGGGGSASIGKQTSTSESKSLTYVNSEVTLNKTEGRLNSLNIKGGEVSI 3051
T NS ++ T G G S Q T Y + L+ + + G+V++
Sbjct 1145 TFSNSGTLLGTSGLGVKGSSLLQHGTGR----LYSAGNLLLDAQDFSGQGQVVATGDVTL 1200
Query 3052 Q------DRGNLQVNNIHVESLQDTASSSNSSRGGSIGGGYGSGSKN---ITASYNQSKG 3102
+ + G L + Q+ ++ +G ++ G G N +TA S
Sbjct 1201 KLIAALTNHGTLAAGKTLSVTSQNAITNGGVMQGDAMVLGAGEAFTNNGMLTAGKGNSVF 1260
Query 3103 SSDSAWVNTTSKLLIGNAQNDANLDAMGVKNITNIGGVIANANKNADGSLTDHKNLNYTG 3162
S+ ++N L G D +L++ I+ G + N G+L + +
Sbjct 1261 SAQRLFLNAPGSLQAGG---DVSLNSRSDITISGFTGTAGSLTMNVAGTLLNSALIYAGN 1317
Query 3163 NLELKDLQDHNNNNSSGFNVSTNIGIPQGGSK-AASTAPKGSTTIGLNSSGQ-ETEQ--- 3217
NL+L + HN + I G S A G+ T +N+SG ET Q
Sbjct 1318 NLKLFTDRLHNQHGD----------ILAGNSLWVQKDASGGANTEIINTSGNIETHQGDI 1367
Query 3218 --LTKATLGQGSVTNATADTNRDINNTQEITRDQTTGMLNGSVTVDHRLLSESGRAEIVK 3275
T L Q +AT T + ++ Q GM N V + LL + +
Sbjct 1368 VVRTGHLLNQREGFSATTTTRTNPSSIQ--------GMGNALVDIPLSLLPDGSYGYFTR 1419
Query 3276 EQE 3278
E E
Sbjct 1420 EVE 1422
Score = 71.2 bits (173), Expect = 4e-14
Identities = 196/958 (20%), Positives = 352/958 (37%), Gaps = 186/958 (19%)
Query 742 NSGSIYADQNIKITGQHILNTGSIAAGQN-IQL-NTAKLQHEQAALIAAGLDRQGKLTST 799
++GS+ + N+++ G +I N+GS QN + L +T + + A LI+AG G L +
Sbjct 1851 HNGSVISGNNVQLAGGNITNSGSSINAQNGLSLDSTGYIDNLNAGLISAG----GSLDLS 1906
Query 800 GDLDITAEQTTLHG-----QSFAGQQLKVASKQQIDATNGQLQAKNIDLASDAGDISTRA 854
DI+ + + G +S +G + +QQ +A + +D G ++T
Sbjct 1907 AIGDISNISSVISGKTVQLESVSGNISNITRRQQWNAGSDSRYGGVHLSGTDTGPVATIK 1966
Query 855 ATVIAEQLSLKSHDLIDNQQGTLSA---------QQLNLTANRL--DNTQGHILHTGQDQ 903
T + LSL + ID T+S+ +N+ AN + +Q HT +
Sbjct 1967 GT---DSLSLDAGKNIDITGATVSSGGTLGMSAGNDINIAANLISGSKSQSGFWHTDDNS 2023
Query 904 LDLNFSQSLNNQLGEIRSNAAELNI----------KTALLNNTEGQVVHAGTQQLNIQTA 953
SQ + G + AA N+ +ALL+ ++A + N +
Sbjct 2024 ASSTTSQGSSISAGGNLAMAAGHNLDVTASSVSAGHSALLSAGNDLSLNAVRESKNSRNG 2083
Query 954 QLNGHLGH-----ILSNGTLQLKAG--TLDVSGGVTSADQITIQANVLNNAQGQLIQRGT 1006
+ H H + + L L AG + GV + + + I+ N + G
Sbjct 2084 RSESHESHAAVSTVTAGDNLLLVAGRDVASQAAGVAAENNVVIRGGRDVNLVAESAGAGD 2143
Query 1007 S--NPLNLTIQQQLNNQAGLIQSATATDIKAG-------SLNNQRGTLSSAQGQNLDVDV 1057
S + I + + Q I S T + AG S G +S G+++ +
Sbjct 2144 SYTSKKKKEINETVRQQGTEIASGGDTTVNAGRDITAVASSVTATGNISVNAGRDVALTT 2203
Query 1058 AGKLD------NSQSGQIYAGNQAHL--------QVGSIDNSHQGQINAQQNLQLTSQQQ 1103
A + D +SG + H + GS+ + ++ +NA NL +
Sbjct 2204 ATESDYHYLETKKKSGGFLSKKTTHTISEDSASREAGSLLSGNRVTVNAGDNLTVEGSDV 2263
Query 1104 INNQSGQIVANGDVQI---------------QSQGL------------------------ 1124
+ +Q + A V + + GL
Sbjct 2264 VADQDVSLAAGNHVDVLAATSTDTSWRFKETKKSGLMGTGGIGFTIGSSKTTHDRREAGT 2323
Query 1125 --NNSHGQMGSLQGGLSLNTGSDTLINQSGLIQAKKDIGIQAQR--IDNQQGQITTQGQA 1180
+ S +GS G +S+ G I+ S +I A +DI I +D + T +
Sbjct 2324 TQSQSASTIGSTAGNVSITAGKQAHISGSDVI-ANRDISITGDSVVVDPGHDRRTVDEKF 2382
Query 1181 ELISQAEIDNLEGAIAADLDVNIRSQGLNNNKGQISSAQGNLTLNAGNGTLTNQAATIVS 1240
E L G + + ++ + S T A +G QAAT+ S
Sbjct 2383 EQKKSGLTVALSGTVGSAINNAVTSAQETKESSDSRLKALQATKTALSGVQAGQAATMAS 2442
Query 1241 --------GKTLTLSANQLDNSNHGQINSQNNADISIVKDINNTSGVIAAKQQLILSSQG 1292
G +L+L+ + + H + ++ + + ++ NN S V K + ++G
Sbjct 2443 ATGDPNATGVSLSLTTQKSKSQQHSESDTVSGSTLNAG---NNLSVVATGKNR--GDNRG 2497
Query 1293 LNNTTGQIGTVQGNLHIDAGSQLL-----NNQQ--GRIQS---GQDLNL----NATGIDN 1338
G V GN +DA + +L N Q+ GR S G +++ N GI
Sbjct 2498 DIVIAGSQLKVGGNTSLDAANDILLSGAANTQKTTGRNSSSGGGVGVSIGAGGNGAGISV 2557
Query 1339 TQGQISSKNQLQLDSREQLLNNRQGTLSAENLTIDSG-----------------ELNNDQ 1381
G ++K + + E T S + +TI+SG ++ +D
Sbjct 2558 FAGVNAAKGSEKGNGTEW---TETTTDSGKTVTINSGRDTVLNGAQVNGNRIIADVGHDL 2614
Query 1382 GLIQAQQSIQIDTHQHNLSNTNSGAQGGILSQGNI------QLNNIQTLDNQQGYLASAQ 1435
+ Q + + D+ Q +++ S G + G I + ++ Q G A
Sbjct 2615 LISSQQDTSKYDSKQTSVAAGGSFTFGSMTGSGYIAASRDKMKSRFDSVAEQTGMFAGDG 2674
Query 1436 QLDLQANQVFNQNGTLLAA------KQLNLQGTGQNQLLN------NQSGQMLSMGGM-- 1481
D+ + +G ++A+ L+ G + L N + SG LS GG
Sbjct 2675 GFDITVGRHTQLDGAVIASTATPDKNHLDTGTLGFSDLHNEADYKVSHSGISLSGGGSFG 2734
Query 1482 -----NLNIDQINNKGKANTADADSHIMAAGELNITTQQLDNQN----TLNTDPANTS 1530
N+ I+ G + A+ + A E IT + DNQ L+ DPA+T+
Sbjct 2735 DKFQGNMPGGMISAGGHSGHAEGTTQ-AAVAEGTITIRDRDNQKQNLANLSRDPAHTN 2791
Score = 66.6 bits (161), Expect = 9e-13
Identities = 198/968 (20%), Positives = 360/968 (37%), Gaps = 145/968 (15%)
Query 353 DLTNTGNLIANQGQLQLNAENIKNTGNISSATSQVSLHS----QNLDNSGLISSADELNI 408
D+T + + +QL NI N+G+ +A + +SL S NL N+GLIS+ L++
Sbjct 1847 DITLHNGSVISGNNVQLAGGNITNSGSSINAQNGLSLDSTGYIDNL-NAGLISAGGSLDL 1905
Query 409 QQQGHVGNRGTLNAARIVVDAGSLANSGSIEQTGAQALDLKAGSMSNIGGKIGIAKTSST 468
G + N ++ + + V N +I + AGS S GG
Sbjct 1906 SAIGDISNISSVISGKTVQLESVSGNISNI----TRRQQWNAGSDSRYGG---------V 1952
Query 469 GGNGSESGGGSQPVEPNNAAQDGGSLEVVNTDSTPTTPKTYETGYIHVRDQLN---NDQG 525
+G+++G + ++ + D G N D T T + T + + +N N
Sbjct 1953 HLSGTDTGPVATIKGTDSLSLDAGK----NIDITGATVSSGGTLGMSAGNDINIAANLIS 2008
Query 526 AIVAQGGI---DLESNNGLDNQGGQLNLGRVKIQGERFNNDQGQLTVKQAEIQTNSLSNQ 582
+Q G D S + +QG ++ G N D +V S N
Sbjct 2009 GSKSQSGFWHTDDNSASSTTSQGSSISAGGNLAMAAGHNLDVTASSVSAGHSALLSAGN- 2067
Query 583 SGQLISNQKLNIQTQTANNQKGKIQSVD-QLDLNVANGLNNIEGQIASGQQLNIQADQVN 641
+ LN ++ N++ G+ +S + ++ +N+ + +G+ + QA V
Sbjct 2068 ------DLSLNAVRESKNSRNGRSESHESHAAVSTVTAGDNL--LLVAGRDVASQAAGVA 2119
Query 642 NQSGLIYSEQQGIELKANHAINNTSGIIQAKTQLNLASTQLDNTSGHIQAENIQQQHTTV 701
++ ++ + + L A A S + K ++N E ++QQ T +
Sbjct 2120 AENNVVIRGGRDVNLVAESAGAGDSYTSKKKKEIN---------------ETVRQQGTEI 2164
Query 702 -NNTQGSIVAGQSLISTVDQFDNHQGLIDAKNIQLTHQVLNNSGSIYADQNIKITGQHIL 760
+ ++ AG+ + + A ++ T + N+G A + H L
Sbjct 2165 ASGGDTTVNAGRDITAV------------ASSVTATGNISVNAGRDVALTTATESDYHYL 2212
Query 761 NTGSIAAGQNIQLNTAKLQHEQAALIAAGLDRQGKLTSTGDLDITAEQTTLHGQS----F 816
T + G + T + + A+ A L ++T ++T E + +
Sbjct 2213 ETKKKSGGFLSKKTTHTISEDSASREAGSLLSGNRVTVNAGDNLTVEGSDVVADQDVSLA 2272
Query 817 AGQQLKVASKQQIDATNGQLQAKNIDLASDAGDISTRAATVIAEQLSLKSHDLIDNQQGT 876
AG + V + D + + K L G T + S +HD + GT
Sbjct 2273 AGNHVDVLAATSTDTSWRFKETKKSGLMGTGGIGFTIGS-------SKTTHD--RREAGT 2323
Query 877 LSAQQLNLTANRLDNTQGHILHTGQDQLDLNFSQSLNNQLGEIRSNAAELNIKTALLNNT 936
+Q +A+ + +T G++ T Q ++ S + N+ I ++ ++ +
Sbjct 2324 TQSQ----SASTIGSTAGNVSITAGKQAHISGSDVIANRDISITGDSVVVD-----PGHD 2374
Query 937 EGQVVHAGTQQLNIQTAQLNGHLGHILSNGTLQLKAGTLDVSGGVTSADQITIQA-NVLN 995
V Q+ + T L+G +G ++N + T + S A Q T A + +
Sbjct 2375 RRTVDEKFEQKKSGLTVALSGTVGSAINNAVTSAQE-TKESSDSRLKALQATKTALSGVQ 2433
Query 996 NAQGQLIQRGTSNPLNLTIQQQLNNQAGLIQSATATDIKAGSLNNQRGTLSSAQGQNLDV 1055
Q + T +P + L Q Q + +D +GS N G NL V
Sbjct 2434 AGQAATMASATGDPNATGVSLSLTTQKSKSQQHSESDTVSGSTLN--------AGNNLSV 2485
Query 1056 DVAGKLDNSQSGQI-YAGNQAHLQVG---SIDNSHQGQINAQQNLQLTSQQQINNQSGQI 1111
GK G I AG+Q L+VG S+D ++ ++ N Q T+ + ++ G
Sbjct 2486 VATGKNRGDNRGDIVIAGSQ--LKVGGNTSLDAANDILLSGAANTQKTTGRNSSSGGGVG 2543
Query 1112 VA-----NGDVQIQSQGLNNSHGQMGSLQGG--------------LSLNTGSDTLINQSG 1152
V+ NG G+N GS +G +++N+G DT++N +
Sbjct 2544 VSIGAGGNGAGISVFAGVN---AAKGSEKGNGTEWTETTTDSGKTVTINSGRDTVLNGAQ 2600
Query 1153 ------LIQAKKDIGIQAQ----RIDNQQGQITTQGQAELISQAEIDNLEGAIAADLD-V 1201
+ D+ I +Q + D++Q + G S G IAA D +
Sbjct 2601 VNGNRIIADVGHDLLISSQQDTSKYDSKQTSVAAGGSFTFGSMTG----SGYIAASRDKM 2656
Query 1202 NIRSQGLNNNKGQISSAQGNLTLNAGNGTLTNQAATIVSGKTLTLSANQLDNSNHGQINS 1261
R + G + G + G T + A V T T N LD G +
Sbjct 2657 KSRFDSVAEQTGMF-AGDGGFDITVGRHTQLDGA---VIASTATPDKNHLDTGTLGFSDL 2712
Query 1262 QNNADISI 1269
N AD +
Sbjct 2713 HNEADYKV 2720
Score = 64.7 bits (156), Expect = 3e-12
Identities = 167/835 (20%), Positives = 301/835 (36%), Gaps = 133/835 (16%)
Query 2506 AGNNIQIHAQQGNVTLLSAIDDKRESSTSSKKGVATYNNRQSGYIDQEVAQTTLKAGDTV 2565
+GNN+Q+ GN+T SS +++ G++ + +GYID A + AG ++
Sbjct 1857 SGNNVQLAG--GNIT-------NSGSSINAQNGLSLDS---TGYIDNLNAGL-ISAGGSL 1903
Query 2566 DINAAKNIELQANDVQAGNSIYVGNTLMQRQADGSLKAADGSLMPENVTLSTLATKDEQW 2625
D++A D+ +S+ G T+ G++ N+T + +QW
Sbjct 1904 DLSAI-------GDISNISSVISGKTVQLESVSGNIS---------NIT------RRQQW 1941
Query 2626 DEQQKGYRGIVKDIVKATAVG----LAGIEALAPGLKAPK---ITVSESTGKRTEQISQT 2678
+ G V + T G + G ++L+ L A K IT + + T +S
Sbjct 1942 NAGSDSRYGGVH--LSGTDTGPVATIKGTDSLS--LDAGKNIDITGATVSSGGTLGMSAG 1997
Query 2679 GSSLKADNVYVGSSGQTTLTSTDI-TAKNTILLGQKVTL--NAAEEQKITVESTSKETVQ 2735
A N+ GS Q+ TD +A +T G ++ N A ++ T+
Sbjct 1998 NDINIAANLISGSKSQSGFWHTDDNSASSTTSQGSSISAGGNLAMAAGHNLDVTASSVSA 2057
Query 2736 GLGAKLNKDSIRLGGFVLEDASQSSKTTETTHKLGSINTENLKIQGVEGVDILGQNITAT 2795
G A L+ + V E + + +E+ +++T +TA
Sbjct 2058 GHSALLSAGNDLSLNAVRESKNSRNGRSESHESHAAVST-----------------VTAG 2100
Query 2796 GDTLIDHGRGDLNVGG---YENKTTVEDKTHVETISTEVGVRNAYLDAALALGAVKDAAE 2852
+ L+ GR + EN + V ++ G ++Y K+ E
Sbjct 2101 DNLLLVAGRDVASQAAGVAAENNVVIRGGRDVNLVAESAGAGDSYTSKKK-----KEINE 2155
Query 2853 AVKQAKDQYSQAQRDYASGKITKEALDDSKANVAMATANLANAQIAVGSAAATAAASSAT 2912
V+Q Q + G T A D A + TA N + G A A+ +
Sbjct 2156 TVRQ------QGTEIASGGDTTVNAGRDITAVASSVTAT-GNISVNAGRDVALTTATESD 2208
Query 2913 YGF--TIGANGERI--ETTNTTNTTQGKWQGSTLELNNLTLKSENQDVNVQGSRLTATGT 2968
Y + T +G + +TT+T + + +L N + ++ V+GS + A
Sbjct 2209 YHYLETKKKSGGFLSKKTTHTISEDSASREAGSLLSGNRVTVNAGDNLTVEGSDVVADQD 2268
Query 2969 TSFDGTKDLNVTAGTEHSQQETSSKTNSQSVSYTYGGGGSASIGKQTSTSESKSLTYVNS 3028
S ++V A T +T + T G G + K T T S
Sbjct 2269 VSLAAGNHVDVLAATSTDTSWRFKETKKSGLMGTGGIGFTIGSSKTTHDRREAGTTQSQS 2328
Query 3029 EVTLNKTEGRLN-----SLNIKGGEVSIQDRGNLQVNNIHVE------SLQDTASSSNSS 3077
T+ T G ++ +I G +V ++ +++ V+ ++ + S
Sbjct 2329 ASTIGSTAGNVSITAGKQAHISGSDVIANRDISITGDSVVVDPGHDRRTVDEKFEQKKSG 2388
Query 3078 RGGSIGGGYGSGSKNITASYNQSKGSSDS------AWVNTTSKLLIGNAQNDANLDAMGV 3131
++ G GS N S ++K SSDS A S + G A A+ A G
Sbjct 2389 LTVALSGTVGSAINNAVTSAQETKESSDSRLKALQATKTALSGVQAGQAATMAS--ATGD 2446
Query 3132 KNITNIGGVI----ANANKNADGSLTDHKNLNYTGNLELKDLQDHNNNN-------SSGF 3180
N T + + + + ++++ LN NL + + +N S
Sbjct 2447 PNATGVSLSLTTQKSKSQQHSESDTVSGSTLNAGNNLSVVATGKNRGDNRGDIVIAGSQL 2506
Query 3181 NVSTNIGIPQGGSKAASTAPKGSTTIGLNSSGQETEQLTKATLGQGSVTNATA------- 3233
V N + S A T G NSS ++ G G+ + A
Sbjct 2507 KVGGNTSLDAANDILLSGAANTQKTTGRNSSSGGGVGVSIGAGGNGAGISVFAGVNAAKG 2566
Query 3234 ----------DTNRDINNTQEITRDQTTGMLNGSVTVDHRLLSESGRAEIVKEQE 3278
+T D T I + T +LNG+ +R++++ G ++ Q+
Sbjct 2567 SEKGNGTEWTETTTDSGKTVTINSGRDT-VLNGAQVNGNRIIADVGHDLLISSQQ 2620
Score = 63.2 bits (152), Expect = 1e-11
Identities = 309/1467 (21%), Positives = 534/1467 (36%), Gaps = 234/1467 (16%)
Query 1870 TRTTESAPGQIKAGGHLD-------LNGAQVVNDKSQILAGGELKNEGGTIDSGTQIAGI 1922
T T ++ G IK+G LD L+G D +++ G L+N G +
Sbjct 439 TATDLTSTGSIKSGSTLDISARNATLSGDAGAKDSARVTVSGTLENRGRLVSDDVLTLSA 498
Query 1923 RKIVNTGTQVKYWKYEGQWDNPFENSSETTFDLSISQALGNQNLNQNQLSTVAVSNNQSA 1982
+I N+GT G + + TT + S++ + GN L+ + ST+A +
Sbjct 499 TQINNSGT------LSGAKELVASADTLTTTEKSVTNSDGNLMLD-SASSTLAGETSAGG 551
Query 1983 EHIQNSQTTQQEINGLQTSNNNTQLNQTKDVDLDQLNLKDSQ-SQNAPQASAVETVQQQS 2041
T + N L+T+ + VD+ L +Q +++ +A E +
Sbjct 552 -------TVSVKGNSLKTTTTAQTQGNSVSVDVQNAQLDGTQAARDILTLNASEKLTHSG 604
Query 2042 ATSAPS---STPQGTSEEI---RSIDFSNIKVPNSALYKVNA----------DSKAGYLI 2085
+SAPS S P+ TS + +++ + + NS L + A + + G L
Sbjct 605 KSSAPSLSLSAPELTSSGVLVGSALNTQSQTLTNSGLLQGEASLTVNTQRLDNQQNGTLY 664
Query 2086 ETDPAFADYKKWLSSDYMLDALGLDPALQQKRLGDGFYEQRLVQDQIA----NLTGYRFL 2141
D +S + GL L L + +++ D ++ L G L
Sbjct 665 SAADLTLDIPDIRNSGLITGDNGL--MLNAVSLSN---PGKIIADTLSVRATTLDGDGLL 719
Query 2142 EGFA----NDDEQYKALMNNGITFAKLYGLRPGIALTAAQTAQLTSDIV----WLVEQSV 2193
+G D + +T L LR G L A T Q + V W SV
Sbjct 720 QGAGALALAGDTLSQGSHGRWLTADDL-SLR-GKTLNTAGTTQGQNITVQADRWANSGSV 777
Query 2194 TLPDGTITKALVPQVYVKVRVGDL--KGDGTLLSGNSVN---------LKLDGD-LINGA 2241
L G +T + Q+ GD+ +GD TL + + N L LDG+ L N
Sbjct 778 -LATGNLTASATGQL---TSTGDIMSQGDTTLKAATTDNRGSLLSAGTLSLDGNSLDNSG 833
Query 2242 TIAGREALQITADNVQNLNGRIQGNQV------AIETQKDLNNIGGQIIAKDAMALKVGG 2295
T+ G + + I ++V N +G + G + Q L N GG ++ + + G
Sbjct 834 TVQG-DHVTIRQNSVTN-SGTLTGIAALTLAARMVSPQPALMNNGGSLLTSGDLTITAGS 891
Query 2296 NLNIES-------TTRTSESKVGNFSSSITNVDRVAGLYVGNGSTKQLDPNQATLMLN-V 2347
+N + T R + V S +T+ +A + ++ Q TL N +
Sbjct 892 LVNSGAIQAADSLTARLTGELVSTAGSKVTSNGEMALSALNLSNSGQWIAKNLTLKANSL 951
Query 2348 AGNSSLKGVQINNSNSATVLNTTGNVDLGTVSVGKQETLKIDD-KNGYQLKQQQDVGSQI 2406
+ GV ++ + TV T N G + TLK D N QL+ G+
Sbjct 952 TSAGDITGV---DTLTLTVNQTLNNQANGKLLSAGVLTLKADSVTNDGQLQ-----GNAT 1003
Query 2407 KSAGSLLINGQNITSKAVDLNSQQGDIQLSAQKDIVLDNGLNQS--TVSSQSQSKGSFGG 2464
L NG ++ + + L + G + ++ N LN S T+S+Q +G G
Sbjct 1004 TITAGQLTNGGHLQGETLTL-AASGGVNNRFGGVLMSRNALNVSTATLSNQGTIQGGGGV 1062
Query 2465 KKSSTYDASSSTSI--ANQLNAGQNIIINSAQGNISATHLQAEAGNNIQIHAQQGNVTLL 2522
+ T + + I + L ++ N+ G + A L + N + G V
Sbjct 1063 SLNVTDRLQNDSKILSGSNLTLTAQVLANTGSGLVQAATLLLDVVNTV----NGGRVLAT 1118
Query 2523 SAIDDKRESSTSSKKGVATYNNRQSGYIDQEVAQTTLKAGD-TVDINAAKNIELQANDVQ 2581
+ D K T NN TL+ D V+ + N + +
Sbjct 1119 GSADVKG----------TTLNN-----------TGTLQGADLLVNYHTFSN----SGTLL 1153
Query 2582 AGNSIYVGNTLMQRQADGSLKAADGSLMPENVTLSTLATKDEQWDEQQKGYRGIVKDIVK 2641
+ + V + + + G L +A L+ + D +G D+
Sbjct 1154 GTSGLGVKGSSLLQHGTGRLYSAGNLLL-------------DAQDFSGQGQVVATGDVTL 1200
Query 2642 ATAVGLAGIEALAPGLKAPKITVSESTGKRTEQISQTGSSLKADNVYVGSSGQTTLTSTD 2701
L LA G T T Q + T + + V +G+ +
Sbjct 1201 KLIAALTNHGTLAAG----------KTLSVTSQNAITNGGVMQGDAMVLGAGEAFTNNGM 1250
Query 2702 ITA--KNTILLGQKVTLNAAEEQK----ITVESTSKETVQGLGAKLNKDSIRLGGFVLED 2755
+TA N++ Q++ LNA + +++ S S T+ G ++ + G +L
Sbjct 1251 LTAGKGNSVFSAQRLFLNAPGSLQAGGDVSLNSRSDITISGFTGTAGSLTMNVAGTLLNS 1310
Query 2756 A-----SQSSKTTETTH-KLGSINTEN-LKIQ-------GVEGVDILGQNITATGDTLID 2801
A + T+ H + G I N L +Q E ++ G T GD ++
Sbjct 1311 ALIYAGNNLKLFTDRLHNQHGDILAGNSLWVQKDASGGANTEIINTSGNIETHQGDIVVR 1370
Query 2802 HGRGDLNVGGYENKTTVEDKTHVETISTEVGVRNAYLDAALALGAVKDAAEAVKQAKDQY 2861
G G+ TT +T+ +I G+ NA +D L+L ++ ++Q+
Sbjct 1371 TGHLLNQREGFSATTTT--RTNPSSIQ---GMGNALVDIPLSLLPDGSYGYFTREVENQH 1425
Query 2862 SQAQRDYASGKITKEALDDSKANVAMATANLANAQIAVGSAAATAAASSATYGFTIGANG 2921
+ + IT + L AT ++Q A A G + A
Sbjct 1426 GTPCNGHGACNITMDTLYYYAPFADSATQRFLSSQNITTVTGADNPAGRIASGRNLSAEA 1485
Query 2922 ERIETTNTTNTTQGKWQGSTLELNNLTLK--SENQDVNVQGSRLTATGTTSFDGTKDLNV 2979
ER+E + G S EL+N + + +EN+ + + T G+ + G+ D
Sbjct 1486 ERLENRASFILANGDIALSGRELSNQSWQTGTENEYLVYRYDPKTFYGSYA-TGSLDKLP 1544
Query 2980 TAGTEHSQQETSSKTNSQSVSYTYG--------GGG------SASIGKQTSTSESKSLTY 3025
E + + YT G GG ++SI T+T+ + S++
Sbjct 1545 LLSPEFENNTIRFSLDGREKDYTPGKTYYSVIQAGGDVKTRFTSSINNGTTTAHAGSVSP 1604
Query 3026 VNSEVTLNKTEGRLNSLNIKGGEVSIQDRGNLQVNNIHVESLQ---DTASSSNSSRGGS- 3081
V S LN+L+ + G S+ Q + V S Q + A + + GGS
Sbjct 1605 VVSAPV-------LNTLSQQTGGDSLTQTALQQYEPVVVGSPQWHDELAGALKNIAGGSP 1657
Query 3082 IGGGYGSGSKNITASYNQS----KGSSDSAWVNTTSKLLIGNAQNDANLDAMGVKNITNI 3137
+ G G S N DS ++ T + L G Q D++L A G+ + +
Sbjct 1658 LTGQTGISDDWPLPSGNNGYLVPSTDPDSPYLITVNPKLDGLGQVDSHLFA-GLYEL--L 1714
Query 3138 GGVIANANKNADGSLTDHKNL----NYTGNLELKDLQDHNNNNSSGFNVS--TNIGIPQG 3191
G A + S TD K + L LK +D+ + F+ +N + +
Sbjct 1715 GAKPGQAPRETAPSYTDEKQFLGSSYFLDRLGLKPEKDYRFLGDAVFDTRYVSNAVLSRT 1774
Query 3192 GSKAASTAPKGSTTIGLNSSGQETEQL 3218
GS+ LN G +TEQ+
Sbjct 1775 GSRY------------LNGLGSDTEQM 1789
Score = 41.6 bits (96), Expect = 3e-05
Identities = 100/543 (18%), Positives = 189/543 (35%), Gaps = 57/543 (10%)
Query 333 VRNAGSMNSTQSTLTLNANGDLTNTGNLIANQGQLQLNAENIKNTGNISSATSQVSLHSQ 392
VR G+ ++ T+NA D+T + + G + +NA ++ ++ S
Sbjct 2157 VRQQGTEIASGGDTTVNAGRDITAVASSVTATGNISVNAG--RDVALTTATESDYHYLET 2214
Query 393 NLDNSGLISSADELNIQQQGH--------VGNRGTLNAA-RIVVDAGSLANSGSIEQTGA 443
+ G +S I + GNR T+NA + V+ + +
Sbjct 2215 KKKSGGFLSKKTTHTISEDSASREAGSLLSGNRVTVNAGDNLTVEGSDVVADQDVSLAAG 2274
Query 444 QALDLKAGSMSNIGGKIGIAKTSSTGGNGSESGGGSQPVEPNNAAQDGGSLEVVNTDSTP 503
+D+ A + ++ + K S G +GG + + D + S
Sbjct 2275 NHVDVLAATSTDTSWRFKETKKSGLMG----TGGIGFTIGSSKTTHDRREAGTTQSQSAS 2330
Query 504 TTPKTYETGYIHVRDQLNNDQGAIVAQGGIDLESNNGLDNQGGQLNLGRVKIQGERFNND 563
T T I Q + ++A I + ++ + + G + E+F
Sbjct 2331 TIGSTAGNVSITAGKQAHISGSDVIANRDISITGDSVVVDPGHDR-----RTVDEKFEQK 2385
Query 564 QGQLTVKQAEIQTNSLSN-----QSGQLISNQKLNIQTQTANNQKGKIQSVDQLDLNVAN 618
+ LTV + ++++N Q + S+ +L T G +Q+ + A
Sbjct 2386 KSGLTVALSGTVGSAINNAVTSAQETKESSDSRLKALQATKTALSG-VQAGQAATMASAT 2444
Query 619 GLNNIEGQIASGQQLNIQADQVNNQSGLIYSEQQGIELKANHAI----------NNTSGI 668
G N A+G L++ + +Q G L A + + +N I
Sbjct 2445 GDPN-----ATGVSLSLTTQKSKSQQHSESDTVSGSTLNAGNNLSVVATGKNRGDNRGDI 2499
Query 669 IQAKTQLNL-ASTQLDNTSGHIQAENIQQQHTTVNNTQGSIVAGQSL--------ISTVD 719
+ A +QL + +T LD + + + Q TT N+ G S+ IS
Sbjct 2500 VIAGSQLKVGGNTSLDAANDILLSGAANTQKTTGRNSSSGGGVGVSIGAGGNGAGISVFA 2559
Query 720 QFDNHQGLIDAKNIQLTH-------QVLNNSGSIYADQNIKITGQHILNTGSIAAGQNIQ 772
+ +G + T V NSG ++ G I+ + Q
Sbjct 2560 GVNAAKGSEKGNGTEWTETTTDSGKTVTINSGRDTVLNGAQVNGNRIIADVGHDLLISSQ 2619
Query 773 LNTAKLQHEQAALIAAGLDRQGKLTSTGDLDITAEQTTLHGQSFAGQQLKVASKQQIDAT 832
+T+K +Q ++ A G G +T +G + + ++ S A Q A D T
Sbjct 2620 QDTSKYDSKQTSVAAGGSFTFGSMTGSGYIAASRDKMKSRFDSVAEQTGMFAGDGGFDIT 2679
Query 833 NGQ 835
G+
Sbjct 2680 VGR 2682
Score = 38.1 bits (87), Expect = 4e-04
Identities = 139/733 (19%), Positives = 260/733 (35%), Gaps = 140/733 (19%)
Query 1878 GQIKAGGHLDLNGAQVVNDKSQILAGG--ELKNEGGTIDSGTQIAGIRKIVNTGTQVKYW 1935
G I AGG LDL+ +++ S +++G +L++ G I + T+ R+ N G+ +Y
Sbjct 1895 GLISAGGSLDLSAIGDISNISSVISGKTVQLESVSGNISNITR----RQQWNAGSDSRY- 1949
Query 1936 KYEGQWDNPFENSSETTFDLSISQALGNQNLNQNQLSTVAVSNNQSAEHIQNSQTTQQEI 1995
G +L+ VA + + + +I
Sbjct 1950 --------------------------GGVHLSGTDTGPVATIKGTDSLSLDAGKNI--DI 1981
Query 1996 NGLQTSNNNT-QLNQTKDVDLDQLNLKDSQSQ----NAPQASAVETVQQQSATSAPSSTP 2050
G S+ T ++ D+++ + S+SQ + SA T Q S+ SA +
Sbjct 1982 TGATVSSGGTLGMSAGNDINIAANLISGSKSQSGFWHTDDNSASSTTSQGSSISAGGNLA 2041
Query 2051 QGTSEEIRSIDFSNIKVPNSALYKVNADSKAGYLIETDPAFADYKKWLSSDYMLDALGLD 2110
+ + S++ +SAL D L L+
Sbjct 2042 MAAGHNL-DVTASSVSAGHSALLSAGND----------------------------LSLN 2072
Query 2111 PALQQKRLGDGFYEQRLVQDQIANLTGYRFLEGFANDDEQYKALMNNGITFAKLYGLRPG 2170
+ K +G E ++ +T L A D +A G+ +R G
Sbjct 2073 AVRESKNSRNGRSESHESHAAVSTVTAGDNLLLVAGRDVASQAA---GVAAENNVVIRGG 2129
Query 2171 IALTAAQTAQLTSDIVWLVEQSVTLPDGTITKALVPQVYVKVRVGDLKGDGTLLSGNSVN 2230
+ + D S T V Q ++ G GD T+ +G +
Sbjct 2130 RDVNLVAESAGAGD-------SYTSKKKKEINETVRQQGTEIASG---GDTTVNAGRDIT 2179
Query 2231 LKLDGDLING--ATIAGREALQITA--------DNVQNLNGRIQGNQVAIETQKDLNNIG 2280
G + AGR+ TA + + G + ++ +
Sbjct 2180 AVASSVTATGNISVNAGRDVALTTATESDYHYLETKKKSGGFLSKKTTHTISEDSASREA 2239
Query 2281 GQIIAKDAMALKVGGNLNIESTTRTSESKV----GNFSS--SITNVD--------RVAGL 2326
G +++ + + + G NL +E + ++ V GN + T+ D + +GL
Sbjct 2240 GSLLSGNRVTVNAGDNLTVEGSDVVADQDVSLAAGNHVDVLAATSTDTSWRFKETKKSGL 2299
Query 2327 YVGNGSTKQLDPNQATLMLNVAGNSSLKGVQINNSNSATVLNTTGNVDLGTVSVGKQETL 2386
G + ++ T AG + + +++T+ +T GNV +++ GKQ +
Sbjct 2300 MGTGGIGFTIGSSKTTHDRREAGTT-------QSQSASTIGSTAGNV---SITAGKQAHI 2349
Query 2387 KIDDKNGYQLKQQQDVGSQIKSAGSLLINGQNITSKAVDLNSQQGDIQLSAQKDIVLDNG 2446
+G + +D I G ++ + VD +Q L+ + +
Sbjct 2350 -----SGSDVIANRD----ISITGDSVVVDPGHDRRTVDEKFEQKKSGLTVALSGTVGSA 2400
Query 2447 LNQSTVSSQSQSKGSFGGKKSSTYDASSSTSIA-NQLNAGQNIIINSAQGNISATHLQAE 2505
+N + S+Q + S S A +T A + + AGQ + SA G+ +AT
Sbjct 2401 INNAVTSAQETKESS-----DSRLKALQATKTALSGVQAGQAATMASATGDPNAT----- 2450
Query 2506 AGNNIQIHAQQGNVTLLSAIDDKRESSTSSKKG---VATYNNRQSGYIDQEVAQTTLKAG 2562
G ++ + Q+ S D S+ ++ VAT NR D +A + LK G
Sbjct 2451 -GVSLSLTTQKSKSQQHSESDTVSGSTLNAGNNLSVVATGKNRGDNRGDIVIAGSQLKVG 2509
Query 2563 DTVDINAAKNIEL 2575
++AA +I L
Sbjct 2510 GNTSLDAANDILL 2522
Score = 28.5 bits (62), Expect = 0.30
Identities = 90/422 (21%), Positives = 150/422 (36%), Gaps = 43/422 (10%)
Query 133 DVGQEGAILNNARNNTQTQLGGWIQGNPWLAKGEAKVILNEVNSSNPSQLKGYIEVAGKQ 192
D G + ++ ++ L + G A A E S+ S+LK ++
Sbjct 2370 DPGHDRRTVDEKFEQKKSGLTVALSGTVGSAINNAVTSAQETKESSDSRLKA-LQATKTA 2428
Query 193 AQVVIANPSGLVCDGCGVINADRFTLT-TGQAVMNQGYLESFRVREGQITIQGKGLNGSL 251
V A + + G NA +L+ T Q +Q + ES V G G L+
Sbjct 2429 LSGVQAGQAATMASATGDPNATGVSLSLTTQKSKSQQHSESDTV-SGSTLNAGNNLSVVA 2487
Query 252 TPFTDVYARALQVNAGLYAKELNVVLGQNDINV-NDPTTSNVSPIQSNTSANNKPQFALD 310
T R V AG K V G ++ ND S + Q T N+ +
Sbjct 2488 TGKNRGDNRGDIVIAGSQLK----VGGNTSLDAANDILLSGAANTQKTTGRNSSSGGGVG 2543
Query 311 VGQLGG-------MYAGKIFLVGTEQGVGVRNAGSMNSTQSTLTLNA------NGDLTNT 357
V G ++AG G+E+G G + + T+T+N+ NG N
Sbjct 2544 VSIGAGGNGAGISVFAGVNAAKGSEKGNGTEWTETTTDSGKTVTINSGRDTVLNGAQVNG 2603
Query 358 GNLIANQGQ---LQLNAENIKNTGNISSATSQVSLHSQNLDNSGLI-SSADELN------ 407
+IA+ G + + K +S + S ++ SG I +S D++
Sbjct 2604 NRIIADVGHDLLISSQQDTSKYDSKQTSVAAGGSFTFGSMTGSGYIAASRDKMKSRFDSV 2663
Query 408 IQQQGHVGNRGTLN---AARIVVDAGSLANSGSIEQTGAQALDLKAGSMSNIGG-KIGIA 463
+Q G G + +D +A++ + ++ L + N K+ +
Sbjct 2664 AEQTGMFAGDGGFDITVGRHTQLDGAVIASTATPDKNHLDTGTLGFSDLHNEADYKVSHS 2723
Query 464 KTS-STGGNGSESGGGSQPVEPNNAAQDGGSLEVVNTDSTPTTPKTYETGYIHVRDQLNN 522
S S GG+ + G+ P +A G E TT G I +RD+ N
Sbjct 2724 GISLSGGGSFGDKFQGNMPGGMISAGGHSGHAE-------GTTQAAVAEGTITIRDRDNQ 2776
Query 523 DQ 524
Q
Sbjct 2777 KQ 2778
Score = 24.6 bits (52), Expect = 4.4
Identities = 20/79 (25%), Positives = 31/79 (39%), Gaps = 2/79 (3%)
Query 3414 GMTILSNIADLGNSIKDISESTGVDIEKVQLAVGLLISGPVRLVIESGKSMAVDSVVGEK 3473
G I N+ NS+ + TGVD + + L +L+ ++ DSV +
Sbjct 937 GQWIAKNLTLKANSLTSAGDITGVDTLTLTVNQTLNNQANGKLLSAGVLTLKADSVTNDG 996
Query 3474 VAQG--VDILANSMTAAAH 3490
QG I A +T H
Sbjct 997 QLQGNATTITAGQLTNGGH 1015
Score = 23.9 bits (50), Expect = 7.5
Identities = 15/40 (38%), Positives = 20/40 (50%), Gaps = 2/40 (5%)
Query 450 AGSMSNIGGKIGIAKTSSTGGNGSESGGGSQPVEPNNAAQ 489
A S NIG + A+ GG+G SG G+ P N+ Q
Sbjct 3101 AASNPNIGKDLTDAEKVELGGSG--SGTGTPPPSENDPKQ 3138
Score = 23.5 bits (49), Expect = 9.8
Identities = 9/30 (30%), Positives = 18/30 (60%), Gaps = 0/30 (0%)
Query 1886 LDLNGAQVVNDKSQILAGGELKNEGGTIDS 1915
+ L+ V++ + LAGG + N G +I++
Sbjct 1848 ITLHNGSVISGNNVQLAGGNITNSGSSINA 1877
>C4SGN7 tRNA nuclease CdiA [Yersinia mollaretii (strain ATCC 43969
/ DSM 18520 / CIP 103324 / CNY 7263 / WAIP 204)]
Length=2963
Score = 362 bits (930), Expect = 2e-102
Identities = 480/1841 (26%), Positives = 791/1841 (43%), Gaps = 267/1841 (15%)
Query 95 GAPTSQQPTILNSS-NGVTQVNIQTPSAGGVSRNTYSQFDVGQEGAILNNARNN-TQTQL 152
G +Q T L+ + NGV VNI P++ GVS N Y+QF+VG EG ILNNA + TQTQL
Sbjct 31 GIDVAQGSTALDKAGNGVPVVNIAPPNSAGVSHNVYNQFNVGSEGVILNNATDRLTQTQL 90
Query 153 GGWIQGNPWLAKGEAKVILNEVNSSNPSQLKGYIEVAGKQAQVVIANPSGLVCDGCGVIN 212
GG IQ N L A I+NEV S+N SQL GY+EV GK A V++ANP G+ CDGCG IN
Sbjct 91 GGLIQSNANLNGKAAGAIINEVVSANRSQLNGYLEVGGKAAAVMVANPYGITCDGCGFIN 150
Query 213 ADRFTLTTGQAVMN-QGYLESFRVREGQITIQGKGLNGSLTPFTDVYARALQVNAGLYAK 271
TLTTG+ +M+ G L+S V +G I+IQGKGL+ S + + +RA ++NA ++A+
Sbjct 151 TPNVTLTTGKPMMDTNGKLQSLDVTQGAISIQGKGLDASQSSALSLISRANEINAQIHAQ 210
Query 272 ELNVVLGQNDINVNDPTTSNVSPIQSNTSANNKPQFALDVGQLGGMYAGKIFLVGTEQGV 331
+L V+ G N ++ + + + PQ ++D G LGGMYA +I LV +E+GV
Sbjct 211 DLTVIAGSNRVD-------SAGHVSERQGQGDVPQVSIDTGALGGMYANRIRLVSSEKGV 263
Query 332 GVRNAGSMNSTQSTLTLNANGDLTNT-----GNLIANQGQLQLNAENIKNTGNISSATSQ 386
GV N G++N+ Q + L++ G LT G++IA+ QL L + GNI+
Sbjct 264 GV-NLGNLNARQGDIQLDSKGKLTVNNAVAHGDIIASADQLHLQGHQ-RAQGNIT----- 316
Query 387 VSLHSQN-LDNSGLISSADELNIQQQGHVGNR-GTLNAARIVVDAGSLANSGSIEQTGA- 443
++ H ++ LDN+ L+ + D L ++ G + ++ LNA V AG++ G++ G+
Sbjct 317 LNSHGESRLDNATLL-AGDTLAVKAGGKITSKESQLNAG--VDSAGNIGEKGTVSLQGSE 373
Query 444 ---QALDLKAGSMSNI-GGKIGIAKTSSTGGNGSESGGGSQPVEPNNAAQDGGSLEVVNT 499
Q + A ++S + G I K SS + G + AA + S+ T
Sbjct 374 LALQQSHVAAAAVSVVSSGDIVQDKESSLTARQLKLSGQHLELAGQLAANNDLSI----T 429
Query 500 DSTPTTPKTYETG-YIHVRDQLNNDQ---GAIVAQGGIDLESNNGLDNQGGQLNLGRVKI 555
+ KT G ++ L D G +VA G + S L N G L ++
Sbjct 430 GQSLRGSKTASVGSQKNITFNLAGDSEWAGQMVA-GNDLIFSGQSLTNHGQLLAANQMHF 488
Query 556 QGERFNNDQGQLTVKQAEIQTNSLSNQSGQLISNQKLNIQTQT-ANNQKGKIQSVDQLDL 614
+G +N QGQ+ I + L+NQ GQL ++ L + + + +G + S L L
Sbjct 489 EGLGLDN-QGQILAADINIAVHRLNNQ-GQLQGDKSLLLTADSLVQSTRGTMNSGRALTL 546
Query 615 NVANGLNNIEGQIASGQQLNIQADQVNNQSGLIYSEQQGIELKANHAINNTSGIIQAKTQ 674
A +I G + S Q L+++ D +N ++ Q+ +L+ H I+N G++ +
Sbjct 547 RAAE--MDISGDLQS-QILDVKGDNWHNHGNVV--AQEHAQLRLGHTIDN-RGVLVSAGD 600
Query 675 LNLASTQLDNTSGHIQAENIQQQHTTVNNTQGSIVAGQSLISTVDQFDNHQGLIDAK--- 731
++L+ QL N G I + ++N+ G +V Q L +D + +QG +
Sbjct 601 MDLSFNQLSN-QGRILGAELALSGKNISNS-GQLVGKQQLSLQLD--EGYQGTSSGELKS 656
Query 732 --NIQLTHQVLNNSGSIYADQNIKITGQHILNTGSI--AAGQNIQLNTAKLQHEQAALIA 787
+ +T +NN G + ++ T Q + N G + QNI L + L ++Q
Sbjct 657 DGLLSVTADEINNQGH-WESGSLNTTAQQLTNNGKVLSVGSQNINL-SGSLTNQQL---- 710
Query 788 AGLDRQGKLTSTGDLDITAEQTTLHGQSFAGQQLKV-ASKQQIDATNGQLQAKNI-DLAS 845
G+ + G+ I AEQ G Q + + KQ T QL K + ++ S
Sbjct 711 ------GQFLTDGEFIIVAEQVINSGLLQGNQAVTLNGLKQYQGGTGSQLLTKGVGEIHS 764
Query 846 DAGDISTRAATVIAEQLSLKSHDLIDNQQGTLSA-QQLNLTANR--LDNTQGHILHTGQD 902
D+ A + A LSL + +++DN GTLS L++ ++ ++ +G +L +
Sbjct 765 DS---VNNAGLIQAGSLSL-TGEVLDN-TGTLSGLSTLHIDSHNEIINQARGQLL--SDN 817
Query 903 QLDLNFSQSLNNQLGEIRSNAAELNIKTALLNNTEGQVVHAGTQQLNIQTAQL-NGHLGH 961
+ L+ Q +NN L EL + + L N G ++ G L +Q L N G
Sbjct 818 TIKLDSEQLVNNGL----MQGTELVLASQHLTN-NGTLL--GLTYLELQAVNLTNSSAGK 870
Query 962 ILSNGTLQLKAGTLDVSGGVTSADQITIQANVLNNAQGQLIQRGTSNPLNLTIQQQLNNQ 1021
ILS L L +G T+ +T +G L +
Sbjct 871 ILSGQDLHFTTSHLQQNGQWTALRDLT------GEIKGAL------------------DF 906
Query 1022 AGLIQSATATDIKAGSLNNQRGTLSSAQGQNLDVDVAGKLDNSQSGQIYAGN-QAHLQVG 1080
+G + + ++ NQRG L QG ++ + G + N SGQ+ AG+ L
Sbjct 907 SGAMAAGKQLSLQVDGDFNQRGNL---QGNDVSITSRGVITN--SGQLAAGSGSLALNGA 961
Query 1081 SIDNSHQGQINAQQNLQLTSQQQINNQSGQIVANGDVQIQSQGLNNSHGQMGSLQGGLSL 1140
+I+ G + + + LTS+ INN+ G + A GD+ +Q+ G N+ L G S+
Sbjct 962 AINQEQSGSLQSGGQISLTSRGDINNR-GFVGAAGDLLLQAIGAVNN---TSLLYAGGSM 1017
Query 1141 NTGSDTLINQSGLIQA-------KKDIGIQAQRIDNQQGQITTQGQAELISQAEIDNLEG 1193
+D + N G I A + + G + I N G I TQ +++ A + N
Sbjct 1018 RLLADAIYNVRGDILAGNHLWMQRDNAGNSNREIINSSGNIETQQGDMVLNTASLLNRRD 1077
Query 1194 AIAADLDVNIRSQGLNNNKGQISSAQGNLTLNAG---NGTLTNQAATIVSGKTLTLSANQ 1250
+ G N+ G + N+ +++G G +T+ + T+ G
Sbjct 1078 GFSV-----TEKTGAVNSGGIANVGATNILISSGYFKPGEVTHYSKTVTGG--------- 1123
Query 1251 LDNSNHGQINSQNNADISIVKDINNTSGVIAAKQQLILSSQGLNNTTGQIGTVQGNLHID 1310
+HG +++ N + +V A KQ+L +T+ I TV +
Sbjct 1124 ---GHHGNVSTVNL--LGLVPS--------ARKQKL--------STSSSIVTVDSPYDV- 1161
Query 1311 AGSQLLNNQQGRIQSGQDLNLNATGIDNTQGQISSKNQLQLDSREQLLNN---RQGTLSA 1367
GRI +G+D+N++A + N Q+S+ L Q LNN + GTL+
Sbjct 1162 ----------GRIVAGRDINISANTLVNQASQMSAGRNALLQG--QSLNNQSYQSGTLTQ 1209
Query 1368 ENLTIDSGELNNDQGLIQAQQSIQIDTHQHNLSNTNSGAQGGILSQGNIQLNNIQTLDNQ 1427
+ ++ + N + L + + S + + +SN QG I + G++ N Q L N
Sbjct 1210 YLVYTNTRDTNPEYNLFEFKLS---GSPTYEISNDGQLYQGVIQAVGSVSANFTQNLSNT 1266
Query 1428 Q------GYLASAQQLDLQANQVFNQNGTLL---AAKQLNLQGTGQNQLLNNQSGQMLSM 1478
+ Q L A V ++ T AA+ G L NQSG L+
Sbjct 1267 SVKPNIGSIVHQVTQPSLTATTVPSELATKPNSGAAQVAPDSNNGDLVALYNQSGTALTF 1326
Query 1479 GGMNLNIDQINNKGKANTADADSHIMAAGELN---ITTQQLDNQNTLNTDPANTSIQGID 1535
G + GK T S N + + ++ ++T+P + +D
Sbjct 1327 G--------LGTDGKPLTRAQLSDYPLPDSNNGLFVVNSEPGSRYLISTNPTLEKLGNVD 1378
Query 1536 ANTLNVTSKVLNNQSGVIRSSADQNLNVQQALNN---------QSGQISSEKQLTLVGD- 1585
+ L+ +L Q ++S N Q + + + +E +GD
Sbjct 1379 STLLSGLQAMLGRQP---QTSVAIERNPQWTQQDNFLGSDYLLKKINLDAEHDYRFLGDA 1435
Query 1586 QLEINNLNGQILAGTALDLIAQSLSGDGKLLSLGNAKLSLQNDYIHSSGAQLQANQDLSL 1645
+ +N +L+ T + L+G G LS Q Y+ + AQ Q DL L
Sbjct 1436 AFDTRYINNAVLSQTG----QRYLNGVGSDLS--------QMQYLLDNAAQSQKKLDLKL 1483
Query 1646 STK----------------GNIINNGTINAGNQLALNAANITNQQAGKIESHDTRLTAQN 1689
NI NG +L L A + Q I + L A
Sbjct 1484 GVSLTPEQVAQLSHSIVWWENINVNGQTVLAPKLYLAKAEQAHLQGSVISGNKVELNA-G 1542
Query 1690 TLNNTGLING-DFTRLQAETLNNQGTGRIYGTTLAIQANTLNNQPD-----STGTAPVIA 1743
++ N+G++ G + + ++ G + + A+ LNN + S + +
Sbjct 1543 SVTNSGVLKGVELLAIASQDTITNEKGGLLTSEGALNLTALNNISNLSSSISGDRVAITS 1602
Query 1744 SRGDLHLGVQTLN---NLSNPTDYTSQALIFSAGNLYLG--AALDANDYAT-GQADVIHN 1797
GD+ QT + S Y S S +G AA+ A T + I
Sbjct 1603 QNGDIINQTQTRQWSADQSRQPGYWSGIKTQSMTQTEVGETAAITAGKALTLAAGNNIAI 1662
Query 1798 ESATIESLGDMNLSAKQINNI--NKYFKTEQVEVSRKDGLE 1836
A + + GD+ + A NI N + +Q + R +E
Sbjct 1663 TGAKVTAAGDIGIQAAHDINIIANDLYSAQQQTLGRNRNIE 1703
Score = 339 bits (870), Expect = 2e-95
Identities = 649/2878 (23%), Positives = 1143/2878 (40%), Gaps = 490/2878 (17%)
Query 832 TNGQLQAKNIDLASDAGDISTRAATVIAEQLSLKSHDLIDNQ-QGTLSAQQLNLTA--NR 888
TNG+LQ+ ++ G IS + + A Q S S N+ + AQ L + A NR
Sbjct 165 TNGKLQSLDVT----QGAISIQGKGLDASQSSALSLISRANEINAQIHAQDLTVIAGSNR 220
Query 889 LDNTQGHILHTGQDQLDLNFSQSLNNQLGEIRSNAAELNIKTALLNNTEGQVVHAGTQQL 948
+D+ GH+ Q Q D+ LG + +N + L+++ +G V+ G
Sbjct 221 VDSA-GHVSER-QGQGDVPQVSIDTGALGGMYAN------RIRLVSSEKGVGVNLGN--- 269
Query 949 NIQTAQLNGHLGHILSNGTLQLKAGTLDVSGGV-TSADQITIQANVLNNAQGQLIQRGTS 1007
LN G I + +L G + SADQ+ +Q + AQG +
Sbjct 270 ------LNARQGDIQLDSKGKLTVNNAVAHGDIIASADQLHLQGH--QRAQGNIT----- 316
Query 1008 NPLNLTIQQQLNNQAGLIQSATATDIKAGSLNNQRGTLSSAQGQ-NLDVDVAGKLDN--- 1063
LN + +L+N L A +KAG G ++S + Q N VD AG +
Sbjct 317 --LNSHGESRLDNATLLAGDTLA--VKAG------GKITSKESQLNAGVDSAGNIGEKGT 366
Query 1064 -SQSGQIYAGNQAHLQVGSIDNSHQGQINAQQNLQLTSQQ-QINNQ----SGQIVANGDV 1117
S G A Q+H+ ++ G I + LT++Q +++ Q +GQ+ AN D+
Sbjct 367 VSLQGSELALQQSHVAAAAVSVVSSGDIVQDKESSLTARQLKLSGQHLELAGQLAANNDL 426
Query 1118 QIQSQGLNNSHGQMGSLQGGLSLNTGSDTLINQSGLIQAKKDIGIQAQRIDNQQGQITTQ 1177
I Q L S Q ++ N D+ +G + A D+ Q + N GQ+
Sbjct 427 SITGQSLRGSKTASVGSQKNITFNLAGDS--EWAGQMVAGNDLIFSGQSLTNH-GQLLAA 483
Query 1178 GQAELISQAEIDNLEGAIAADLDVNIRSQGLNNNKGQISSAQGNLTLNAGNGTLTNQAAT 1237
Q +DN +AAD+++ + NN+GQ+ + +L L A + + + T
Sbjct 484 NQMHFEGLG-LDNQGQILAADINIAVHRL---NNQGQLQGDK-SLLLTA-DSLVQSTRGT 537
Query 1238 IVSGKTLTLSANQLDNSNHGQINSQNNADISIVKDINNTSGVIAAKQQLILSSQGLNNTT 1297
+ SG+ LTL A ++D S G + SQ + + D + G + A++ L L +T
Sbjct 538 MNSGRALTLRAAEMDIS--GDLQSQI---LDVKGDNWHNHGNVVAQEHAQLR---LGHTI 589
Query 1298 GQIGTVQGNLHIDAGSQLLNNQQGRIQSGQDLNLNATGIDNTQGQISSKNQLQLDSREQL 1357
G + +D L+NQ GRI G +L L+ I N+ GQ+ K QL L E
Sbjct 590 DNRGVLVSAGDMDLSFNQLSNQ-GRIL-GAELALSGKNISNS-GQLVGKQQLSLQLDEGY 646
Query 1358 LNNRQGTLSAENLTIDSGELNNDQGLIQAQQSIQIDTHQHNLSNTNSGAQGGILSQGNIQ 1417
G L ++ L + + N+QG +S ++T L+N G +LS G+
Sbjct 647 QGTSSGELKSDGLLSVTADEINNQG---HWESGSLNTTAQQLTNN-----GKVLSVGSQN 698
Query 1418 LNNIQTLDNQQ-GYLASAQQLDLQANQVFNQNGTLLAAKQLNLQGTGQNQLLNNQSGQML 1476
+N +L NQQ G + + + A QV N +G L + + L G Q Q Q+L
Sbjct 699 INLSGSLTNQQLGQFLTDGEFIIVAEQVIN-SGLLQGNQAVTLNGLKQYQ--GGTGSQLL 755
Query 1477 SMGGMNLNIDQINNKGKANTADADSHIMAAGELNITTQQLDNQNTLNTDPANTSIQGIDA 1536
+ G ++ D +NN G ++ AG L++T + LDN TL+ G+
Sbjct 756 TKGVGEIHSDSVNNAG----------LIQAGSLSLTGEVLDNTGTLS---------GLST 796
Query 1537 NTLNVTSKVLNNQSGVIRSSADQNLNVQQALNNQSGQ----ISSEKQLTLVGDQLEI--- 1589
++ ++++N G + S L+ +Q +NN Q + + + LT G L +
Sbjct 797 LHIDSHNEIINQARGQLLSDNTIKLDSEQLVNNGLMQGTELVLASQHLTNNGTLLGLTYL 856
Query 1590 --------NNLNGQILAGTALDLIAQSLSGDGKLLSL------------------GNAKL 1623
N+ G+IL+G L L +G+ +L +L
Sbjct 857 ELQAVNLTNSSAGKILSGQDLHFTTSHLQQNGQWTALRDLTGEIKGALDFSGAMAAGKQL 916
Query 1624 SLQNDYIHSSGAQLQANQDLSLSTKGNIINNGTINAGN-QLALNAANITNQQAGKIESH- 1681
SLQ D + LQ N D+S++++G I N+G + AG+ LALN A I +Q+G ++S
Sbjct 917 SLQVDGDFNQRGNLQGN-DVSITSRGVITNSGQLAAGSGSLALNGAAINQEQSGSLQSGG 975
Query 1682 DTRLTAQNTLNNTGLINGDFTRLQAETLNNQGTGRIYGTTLAIQANTLNNQPDSTGTAPV 1741
LT++ +NN G + A L Q G + T+L ++ D+ +
Sbjct 976 QISLTSRGDINNRGFVGA------AGDLLLQAIGAVNNTSLLYAGGSMRLLADA-----I 1024
Query 1742 IASRGDL----HLGVQTLNNLSNPTDYTSQALIFSAGNLYLGAALDANDYATGQADVIHN 1797
RGD+ HL +Q +N N +++ +I S+GN+ D A +++
Sbjct 1025 YNVRGDILAGNHLWMQR-DNAGN----SNREIINSSGNI----ETQQGDMVLNTASLLNR 1075
Query 1798 --------ESATIESLGDMNLSAKQINNINKYFKTEQVEVSRKDGLEKYCDAWCTFDGNY 1849
++ + S G N+ A I + YFK +V K T G
Sbjct 1076 RDGFSVTEKTGAVNSGGIANVGATNILISSGYFKPGEVTHYSK-----------TVTGGG 1124
Query 1850 YDGNPYEDWMRYYYSEITYETRTTESA---------PGQIKAGGHLDLNGAQVVNDKSQI 1900
+ GN + + +T S+ G+I AG ++++ +VN SQ+
Sbjct 1125 HHGNVSTVNLLGLVPSARKQKLSTSSSIVTVDSPYDVGRIVAGRDINISANTLVNQASQM 1184
Query 1901 LAGGELKNEGGTIDSGTQIAGIRKIVNTGTQVKYWKYEGQWD-NPFENSSETTFDLSISQ 1959
AG +G ++++ + +GT +Y Y D NP N E F LS S
Sbjct 1185 SAGRNALLQGQSLNNQSY--------QSGTLTQYLVYTNTRDTNPEYNLFE--FKLSGSP 1234
Query 1960 ALGNQNLNQNQLSTVAVSNNQSAEHIQNSQTTQQEINGLQTSNNNTQLNQTKDVDLDQLN 2019
N Q + + SA QN T + N + TQ + T +L
Sbjct 1235 TYEISNDGQLYQGVIQAVGSVSANFTQNLSNTSVKPNIGSIVHQVTQPSLTATTVPSELA 1294
Query 2020 LKDSQ--SQNAPQASAVETVQQQSATSAPSSTPQGTS-EEIRSIDFSNIKVP--NSALYK 2074
K + +Q AP ++ + V + + + GT + + S+ +P N+ L+
Sbjct 1295 TKPNSGAAQVAPDSNNGDLVALYNQSGTALTFGLGTDGKPLTRAQLSDYPLPDSNNGLFV 1354
Query 2075 VNADSKAGYLIETDPA----------------------------------FADYKKWLSS 2100
VN++ + YLI T+P + +L S
Sbjct 1355 VNSEPGSRYLISTNPTLEKLGNVDSTLLSGLQAMLGRQPQTSVAIERNPQWTQQDNFLGS 1414
Query 2101 DYMLDALGLDPALQQKRLGDGFYEQRLVQDQIANLTGYRFLEGFANDDEQYKALMNNGIT 2160
DY+L + LD + LGD ++ R + + + + TG R+L G +D Q + L++N
Sbjct 1415 DYLLKKINLDAEHDYRFLGDAAFDTRYINNAVLSQTGQRYLNGVGSDLSQMQYLLDNAAQ 1474
Query 2161 FAKLYGLRPGIALTAAQTAQLTSDIVWLVEQSVTLPDGTITKALVPQVYVKVRVGDLKGD 2220
K L+ G++LT Q AQL+ IVW +++ + T+ L P++Y+ +
Sbjct 1475 SQKKLDLKLGVSLTPEQVAQLSHSIVWW--ENINVNGQTV---LAPKLYL-AKAEQAHLQ 1528
Query 2221 GTLLSGNSVNLKLDGDLINGATIAGREALQITA-DNVQNLNGRIQGNQVAIE--TQKDLN 2277
G+++SGN V L G + N + G E L I + D + N G + ++ A+ +++
Sbjct 1529 GSVISGNKVELNA-GSVTNSGVLKGVELLAIASQDTITNEKGGLLTSEGALNLTALNNIS 1587
Query 2278 NIGGQIIAKDAMALKVGGNLNIESTTRTSESKVGNFSSSITNVDRVAGLYVGNGSTKQLD 2337
N+ I G++ ++ TR + + + + G T +
Sbjct 1588 NLSSSISGDRVAITSQNGDIINQTQTRQWSADQSRQPGYWSGIKTQSMTQTEVGETAAIT 1647
Query 2338 PNQATLMLNVAGNSSLKGVQINNSNSATVLNTTG-NVDLGTVSVGKQETLKIDDKNGYQL 2396
+A L L N ++ G ++ + + N+ + +Q+TL +L
Sbjct 1648 AGKA-LTLAAGNNIAITGAKVTAAGDIGIQAAHDINIIANDLYSAQQQTL--GRNRNIEL 1704
Query 2397 KQQQDVGSQIKSAGSLLI--NGQNITSKAVDLNSQQGDIQLSAQKDIVLDNGLNQSTVSS 2454
+Q + S SAG L G++IT A L + G+ L A++D+ L V
Sbjct 1705 NEQHESQSSHVSAGGTLTAHAGRDITLSASHLGA-DGNATLQAERDVNL-------LVQE 1756
Query 2455 QSQSKGSFGGKKSSTYDASSSTSIANQLNAGQNIIINSAQGNISATH-LQAEAGNNIQIH 2513
+S + +T S+ S L A INS ++A + L AG +I ++
Sbjct 1757 KSTRNQHIDSEDKTTGYTRSTLSSGGDLTASAGRDINSQAAAVTAENTLALNAGRDINLN 1816
Query 2514 AQQGNVTLLSAIDDKRESSTSSKKGVATYNNRQSGYIDQEVAQ--TTLKAGDTVDINAAK 2571
AQ + R+ + S K +D+ + Q T L +G ++A +
Sbjct 1817 AQ-----------ESRQYNESHGKNYKR--------VDEAIRQQGTELASGKGTQVHAGQ 1857
Query 2572 NIELQANDVQAGNSIYVGNTLMQRQADGSLKAADGSLMPENVTLSTLATKDEQWDEQQKG 2631
+I L A + A + D +L+A ++ +++ D + E++
Sbjct 1858 DINLHAASISA-------------KGDLALQAG------RDIAVNSATESDYHFFEEK-- 1896
Query 2632 YRGIVKDIVKATAVGLAGIEALAPGLKAPKITVSESTGKRTEQ---ISQTGSSLKADNVY 2688
K K VS++T E+ ++ S+L +NV
Sbjct 1897 --------------------------KTKKKLVSKTTIHNVEEDFATTEKSSALVGNNVS 1930
Query 2689 VGSSGQTTLTSTDITAKNTILL--GQKVTLNAAEEQKITVESTSKETV-----QGLGAKL 2741
+ + + + + T++L V + AA EQ+ + K+T GLG L
Sbjct 1931 LSAGNNLIVKGSSVVGDGTVVLKADNNVDIVAATEQQSSYRLNEKKTSGMFSGGGLGVTL 1990
Query 2742 NKDSIRLGGFVLEDASQSSKTTETTHKLGSINTENLKIQGVEGVDILGQNITATGDTLID 2801
S R + + SK +E+ +GS N+ I I G ++ A D +
Sbjct 1991 GSKSSR-----QQINQEGSKQSESASAVGS-TAGNVSILAGAQAHISGSDVIAGKDLNVI 2044
Query 2802 HGRGDLNVGG--YENKTTVEDKTHVETISTEVGVRNAYLDAALALGAVKDAAEAVKQAKD 2859
G ++ G + + E K T+S + + + DA LA+ + +KQA D
Sbjct 2045 AGTIKVDPGNDVLKRRQIYEQKQSGLTLS----LSSPFTDALLAINS------KLKQASD 2094
Query 2860 QYSQAQRDYASGKITKEALDDSKANVAMATANLANAQIAVGSAAATAAASSATYGFTIGA 2919
S + +EA + M + G AA A S ++GA
Sbjct 2095 AGSDKLSALYGAQAAREAWVGVDGTMDMMASK-------PGGPAADPGA-SIKLQLSVGA 2146
Query 2920 NGERIETTNTTNTTQGKWQGSTLEL-NNLTL-----KSENQDVNVQGSRLTATGTTSFDG 2973
+ + +T+ Q + +GS+L +NLT+ ++ D++V GS +T T
Sbjct 2147 S----HSKSTSELAQNQTRGSSLTAGDNLTMVASGDHEQSGDLSVVGSGVTGNKVT-LVA 2201
Query 2974 TKDLNVTAGTEHSQQETSSKTNSQSVSYTYGGGGSASIGKQT------------STSESK 3021
D+ + A + +S+Q S+ S + G S+GK+T S+ K
Sbjct 2202 KNDVLLAAASNNSEQ------TSRDSSSGWNAGVHLSLGKETGIGIAANGFMSKGNSDGK 2255
Query 3022 SLTYVNSEVTLNK----TEGR---LNSLNIKGGEVSIQDRGNLQVNNI----HVESLQDT 3070
+ Y N+ + + GR L+ + G +++ + +L ++++ + S+Q
Sbjct 2256 TTDYANARINAKEALAINSGRDTVLSGAQVLGDKITAEIGRDLTISSLQDSDNYNSIQKD 2315
Query 3071 ASSSNSSRGGSIGGGYGSGSKNITASYNQSKGSSDSAWVNTTSKLLIGNAQNDANLDAMG 3130
AS+ S G GGG S S ++K S A V S G+ D N
Sbjct 2316 ASAGFSFTFGPSGGGSAS------FSLGKTKIESKYASVGDQSGFFAGSKGFDLN----- 2364
Query 3131 VKNITNI-GGVIANANKNADGSLTDHKNLNYTGNLELKDL--QDHNNNNSSGFNVSTNIG 3187
V N T + GGV+A+ D NL TG L D+ Q S+ ST+
Sbjct 2365 VGNHTQLNGGVLASTAGAQD-------NLLSTGTLGWGDIHNQAEYKATSTRIGYSTDAP 2417
Query 3188 IPQGGSKAASTAPKGST-------TIGLNSSGQETEQLTKATLGQGSVTNATADTNRDIN 3240
+P G A + G+T I + + G++ + +T + S N D D +
Sbjct 2418 MPTLGMANAHGSASGTTRSAVASGEIEIRNQGEQQQDVTTLSRDTDS-ANGRIDKIFDES 2476
Query 3241 N-------TQEITRDQTTGMLNGSVTVDHRLLSESGRAEIVKEQEQLIENFRQSAENLAK 3293
TQ +T Q L G V+ + +E AE +++ + R+ + +
Sbjct 2477 KVKDQMAFTQGVT--QLATQLVGDVSSWNMKQAERSAAEKLEKDPKYQNATREKRQEMIY 2534
Query 3294 ALPDGVYKDKALQTLNDVQAKLYNLPSEYKEVGVVGNSVASELLKRGMESQDVEALFSKL 3353
A D YK + + + S + G+ ++ + L + D+ ++ S
Sbjct 2535 ASAD--YK---------AAQESFGIGSSFWTAGMAVSAALTGL----AGNADIGSISSAA 2579
Query 3354 DFFYAAKEFSEIQNQLTDLEKSGVN------LETIFKQPKAGVNEQETIYAQGTDFETKV 3407
Y A + + D +N L I Q + + G +
Sbjct 2580 VAPYLAGQIKKYTTDKDDKVNKTINILAHAILGGIVAQMQGNSATAGALGGGGGE----- 2634
Query 3408 RSQTTLGMTILSNIADLGNSIKDISESTGVDIEKVQLAVGLLISGPV-RLVIESGKSMAV 3466
L I + G + D+SE+ +K+ A+G L +G + L +S +
Sbjct 2635 -----LAARIYMDQVHPGKKVSDLSEAD----KKIVSAIGTLTAGILGGLSTDSSTGLIT 2685
Query 3467 DSVVGEKVAQGVDILANSMTA----AAHDTSVNTINNWTNPDKISE--LENSTGENKD 3518
+ G+ + ++ A + V+ + N T+PD++S ++NS G+ +
Sbjct 2686 GAQAGKNAVEDNNLSFGKGMADIGMSQTSLGVSMLRNGTSPDEVSAALVKNSLGQTPE 2743
Score = 179 bits (455), Expect = 5e-47
Identities = 445/2037 (22%), Positives = 768/2037 (38%), Gaps = 323/2037 (16%)
Query 53 GFDSSHLKKLKQLNFAVISVLGASIFTLPLNTIADSQIIADKGAPTSQQPTILNSSNGVT 112
G D+S L ++ A + + A I L IA S + G + +Q V
Sbjct 185 GLDASQSSALSLISRA--NEINAQIHAQDLTVIAGSNRVDSAGHVSERQ-----GQGDVP 237
Query 113 QVNIQTPSAGGVSRNTY----SQFDVGQEGAILNNARNNTQTQLGGWIQGNPWLAKGEAK 168
QV+I T + GG+ N S+ VG LN + + Q G + N +A G+
Sbjct 238 QVSIDTGALGGMYANRIRLVSSEKGVGVNLGNLNARQGDIQLDSKGKLTVNNAVAHGDII 297
Query 169 VILNEVNSSNPSQLKGYIEVAGKQAQVVIANPSGLVCDGCGVINADRFTLTTGQAVMNQG 228
++++ + +G I + + + N + L D V + +T+ ++ +N G
Sbjct 298 ASADQLHLQGHQRAQGNITL-NSHGESRLDNATLLAGDTLAVKAGGK--ITSKESQLNAG 354
Query 229 YLESFRVRE-GQITIQGKGLNGSLTPFTDVYARALQVNAGLYAKELNVVLGQNDINVNDP 287
+ + E G +++QG L ALQ + + A ++VV
Sbjct 355 VDSAGNIGEKGTVSLQGSEL-------------ALQ-QSHVAAAAVSVV----------- 389
Query 288 TTSNVSPIQSNTSANNKPQFALDVGQ---LGGMYAGKIFLVGTEQGVGVRNAGSMNSTQS 344
S+ +Q S+ Q L GQ L G A L T Q + S+ S Q
Sbjct 390 --SSGDIVQDKESSLTARQLKLS-GQHLELAGQLAANNDLSITGQSLRGSKTASVGS-QK 445
Query 345 TLTLNANGDLTNTGNLIANQGQLQLNAENIKNTGNISSATSQVSLHSQNLDNSGLISSAD 404
+T N GD G ++A L + +++ N G + +A +Q+ LDN G I +AD
Sbjct 446 NITFNLAGDSEWAGQMVAGN-DLIFSGQSLTNHGQLLAA-NQMHFEGLGLDNQGQILAAD 503
Query 405 ELNIQQQGHVGNRGTLNAAR-IVVDAGSLANSGSIEQTGAQALDLKAGSMSNIGGKIGIA 463
+NI + N+G L + +++ A SL S +AL L+A M +I G +
Sbjct 504 -INIAVH-RLNNQGQLQGDKSLLLTADSLVQSTRGTMNSGRALTLRAAEM-DISGDLQSQ 560
Query 464 KTSSTGGNGSESGGGSQPVEPNNAAQDGGSLEVVNTDSTPTTPKTYETGYIHVRDQLNND 523
G N G N AQ+ L + +T ++
Sbjct 561 ILDVKGDNWHNHG--------NVVAQEHAQLRLGHTI---------------------DN 591
Query 524 QGAIVAQGGIDLESNNGLDNQGGQLNLGRVKIQGERFNNDQGQLTVKQA---EIQTNSLS 580
+G +V+ G +DL S N L NQG L + + G+ +N GQL KQ ++
Sbjct 592 RGVLVSAGDMDL-SFNQLSNQGRILG-AELALSGKNISNS-GQLVGKQQLSLQLDEGYQG 648
Query 581 NQSGQLISNQKLNIQTQTANNQKGKIQSVDQLDLNVANGLNNIEGQIASGQQLNIQADQV 640
SG+L S+ L++ NNQ G +S L+ NN + Q +N+
Sbjct 649 TSSGELKSDGLLSVTADEINNQ-GHWES-GSLNTTAQQLTNNGKVLSVGSQNINLSGSLT 706
Query 641 NNQSGLIYSEQQGIELKANHAINNTSGIIQAK--TQLNLASTQLDNTSGHIQAENIQQQH 698
N Q G ++ + I + A IN SG++Q LN T + + + + H
Sbjct 707 NQQLGQFLTDGEFI-IVAEQVIN--SGLLQGNQAVTLNGLKQYQGGTGSQLLTKGVGEIH 763
Query 699 TTVNNTQGSIVAGQSLISTVDQFDNHQGL--IDAKNIQLTHQVLNNS-GSIYADQNIKIT 755
+ N G I AG SL T + DN L + +I ++++N + G + +D IK+
Sbjct 764 SDSVNNAGLIQAG-SLSLTGEVLDNTGTLSGLSTLHIDSHNEIINQARGQLLSDNTIKLD 822
Query 756 GQHILNTGS------IAAGQNIQLNTAKLQHEQAALIAAGLDRQ--GKLTSTGDLDITAE 807
+ ++N G + A Q++ N L L A L GK+ S DL T
Sbjct 823 SEQLVNNGLMQGTELVLASQHLTNNGTLLGLTYLELQAVNLTNSSAGKILSGQDLHFTTS 882
Query 808 QTTLHGQSFAGQQLKVASKQQIDATNGQLQAKNIDLASDAGDISTRAATVIAEQLSLKSH 867
+GQ A + L K +D + K + L D GD
Sbjct 883 HLQQNGQWTALRDLTGEIKGALDFSGAMAAGKQLSLQVD-GDF----------------- 924
Query 868 DLIDNQQGTLSAQQLNLTANRLDNTQGHILHTGQDQLDLNFSQSLNNQLGEIRSNAAELN 927
NQ+G L +++T+ + G L G L LN + Q G ++S +++
Sbjct 925 ----NQRGNLQGNDVSITSRGVITNSGQ-LAAGSGSLALNGAAINQEQSGSLQSGG-QIS 978
Query 928 IKTALLNNTEGQVVHAGTQQLNIQTAQLNGHLGHILSNGTLQLKAGTL-DVSGGVTSADQ 986
+ + N G V AG L A N L + + G+++L A + +V G + + +
Sbjct 979 LTSRGDINNRGFVGAAGDLLLQAIGAVNNTSL--LYAGGSMRLLADAIYNVRGDILAGNH 1036
Query 987 ITIQANVLNNAQGQLIQRGTSNPLNLTIQQ--QLNNQAGLIQSATATDI--KAGSLNNQR 1042
+ +Q + N+ ++I N+ QQ + N A L+ + K G++N+
Sbjct 1037 LWMQRDNAGNSNREIINSSG----NIETQQGDMVLNTASLLNRRDGFSVTEKTGAVNS-- 1090
Query 1043 GTLSSAQGQNLDVDVAGKLDNSQSGQIYAGNQAHLQVGSIDNSHQGQINAQQNLQLTS-- 1100
G +++ N+ + SG G H H G ++ L L
Sbjct 1091 GGIANVGATNILIS---------SGYFKPGEVTHYSKTVTGGGHHGNVSTVNLLGLVPSA 1141
Query 1101 -QQQINNQSGQIVANGDVQIQSQGLNNSHGQMGSLQGGLSLNTGSDTLINQSGLIQAKKD 1159
+Q+++ S + + + G + G +N ++TL+NQ+ + A ++
Sbjct 1142 RKQKLSTSSSIVTVDSPYDV------------GRIVAGRDINISANTLVNQASQMSAGRN 1189
Query 1160 IGIQAQRIDNQQGQITTQGQAELISQAEIDNLEGAI-------AADLDVNIRSQGLNNNK 1212
+Q Q ++NQ Q T Q + + N E + + +++ Q
Sbjct 1190 ALLQGQSLNNQSYQSGTLTQYLVYTNTRDTNPEYNLFEFKLSGSPTYEISNDGQLYQGVI 1249
Query 1213 GQISSAQGNLTLNAGN-------GTLTNQA------ATIVSGKTLTL----SANQLDNSN 1255
+ S N T N N G++ +Q AT V + T +A +SN
Sbjct 1250 QAVGSVSANFTQNLSNTSVKPNIGSIVHQVTQPSLTATTVPSELATKPNSGAAQVAPDSN 1309
Query 1256 HGQINSQNNADISIVKDINNTSGVIAAKQQL-------------ILSSQ-------GLNN 1295
+G + + N + + T G + QL +++S+ N
Sbjct 1310 NGDLVALYNQSGTALTFGLGTDGKPLTRAQLSDYPLPDSNNGLFVVNSEPGSRYLISTNP 1369
Query 1296 TTGQIGTVQGNLHIDAGSQLLNNQQGRIQSGQDLNLNATGIDNTQGQISSKNQLQLDSRE 1355
T ++G V L +G Q + +Q + + N T DN G ++ LD+
Sbjct 1370 TLEKLGNVDSTLL--SGLQAMLGRQPQTSVAIERNPQWTQQDNFLGSDYLLKKINLDAEH 1427
Query 1356 ------------QLLNNRQGTLSAENLTIDSG-ELNNDQGLI----QAQQSIQIDTHQHN 1398
+ +NN + + + G +L+ Q L+ Q+Q+ + +
Sbjct 1428 DYRFLGDAAFDTRYINNAVLSQTGQRYLNGVGSDLSQMQYLLDNAAQSQKKLDLKLGVSL 1487
Query 1399 LSNTNSGAQGGILSQGNIQLNNIQTLDNQQGYLASAQQLDLQANQVFNQNGTLLAAKQLN 1458
+ I+ NI +N QT+ + YLA A+Q LQ + + L A N
Sbjct 1488 TPEQVAQLSHSIVWWENINVNG-QTVLAPKLYLAKAEQAHLQGSVISGNKVELNAGSVTN 1546
Query 1459 ---LQGT------GQNQLLNNQSGQMLSMGGMNLN-IDQINNKGKANTADADSHIMAAGE 1508
L+G Q+ + N + G + S G +NL ++ I+N + + D + G+
Sbjct 1547 SGVLKGVELLAIASQDTITNEKGGLLTSEGALNLTALNNISNLSSSISGDRVAITSQNGD 1606
Query 1509 LNITTQQLDNQNTLNTDPANTSIQGIDANTLNVTS----------KVLNNQSG------- 1551
+ TQ + P S GI ++ T K L +G
Sbjct 1607 IINQTQTRQWSADQSRQPGYWS--GIKTQSMTQTEVGETAAITAGKALTLAAGNNIAITG 1664
Query 1552 -VIRSSADQNLNVQQALNNQSGQISSEKQLTLVGDQ-LEINNLN---------GQIL--- 1597
+ ++ D + +N + + S +Q TL ++ +E+N + G L
Sbjct 1665 AKVTAAGDIGIQAAHDINIIANDLYSAQQQTLGRNRNIELNEQHESQSSHVSAGGTLTAH 1724
Query 1598 AGTALDLIAQSLSGDGKLLSLGNAKLSLQNDYIHSSGAQLQANQDLSLSTKGNIINNGTI 1657
AG + L A L DG NA L + D + NQ + K T+
Sbjct 1725 AGRDITLSASHLGADG------NATLQAERDVNLLVQEKSTRNQHIDSEDKTTGYTRSTL 1778
Query 1658 NAGNQLALNAANITNQQAGKIESHDT---------RLTAQNTLNNTGLINGDFTRLQAET 1708
++G L +A N QA + + +T L AQ + ++ R+ E
Sbjct 1779 SSGGDLTASAGRDINSQAAAVTAENTLALNAGRDINLNAQESRQYNESHGKNYKRVD-EA 1837
Query 1709 LNNQGTGRIYGTTLAIQANTLNNQPDSTGTAPVIASRGDLHL--GVQTLNNLSNPTDY-- 1764
+ QGT G + A D A I+++GDL L G N + +DY
Sbjct 1838 IRQQGTELASGKGTQVHAGQ-----DINLHAASISAKGDLALQAGRDIAVNSATESDYHF 1892
Query 1765 -----TSQALIFSA---------GNLYLGAALDANDYATGQADVIHNESATIESLGDMNL 1810
T + L+ +AL N+ + + + + +++ +GD +
Sbjct 1893 FEEKKTKKKLVSKTTIHNVEEDFATTEKSSALVGNNVSLSAGNNLIVKGSSV--VGDGTV 1950
Query 1811 SAKQINNINKYFKTEQVEVSRKDGLEKYCDAWCTFDGNYYDGNPYEDWMRYYYSEITYET 1870
K NN++ TEQ R + EK F G R ++ +
Sbjct 1951 VLKADNNVDIVAATEQQSSYRLN--EKKTSGM--FSGGGLGVTLGSKSSRQQINQEGSKQ 2006
Query 1871 RTTESAPGQIKAGGHLDLNGAQVVNDKSQILAGGELKNEGGTI--DSGTQIAGIRKI 1925
+ SA G AG L GAQ S ++AG +L GTI D G + R+I
Sbjct 2007 SESASAVGST-AGNVSILAGAQAHISGSDVIAGKDLNVIAGTIKVDPGNDVLKRRQI 2062
Score = 132 bits (333), Expect = 8e-33
Identities = 404/1888 (21%), Positives = 697/1888 (37%), Gaps = 329/1888 (17%)
Query 158 GNPWLAKGEAKVILNEVNSSNPSQLKGYIEVAGKQ----------AQVVIANPSGLVCDG 207
G+ L KG ++ + VN++ Q G + + G+ + + I + + ++
Sbjct 751 GSQLLTKGVGEIHSDSVNNAGLIQA-GSLSLTGEVLDNTGTLSGLSTLHIDSHNEIINQA 809
Query 208 CGVINADRFTLTTGQAVMNQGYLESFRVREGQITIQGKGLNGSLTPFTDVYARALQVNAG 267
G + +D + ++N G ++ E + Q NG+L T + +A+ +
Sbjct 810 RGQLLSDNTIKLDSEQLVNNGLMQG---TELVLASQHLTNNGTLLGLTYLELQAVNLTNS 866
Query 268 LYAKELNVVLGQNDINVNDPTTSNVSPIQSNTSANN---KPQFALDVGQLGGMYAGKIFL 324
K +L D++ TTS++ T+ + + + ALD G M AGK
Sbjct 867 SAGK----ILSGQDLHF---TTSHLQQNGQWTALRDLTGEIKGALDFS--GAMAAGKQLS 917
Query 325 VGTEQGVGVRNAGSMNSTQSTLTLNANGDLTNTGNLIANQGQLQLN--AENIKNTGNISS 382
+ + R N + +++ + G +TN+G L A G L LN A N + +G++ S
Sbjct 918 LQVDGDFNQRG----NLQGNDVSITSRGVITNSGQLAAGSGSLALNGAAINQEQSGSLQS 973
Query 383 ATSQVSLHSQ-NLDNSGLISSADELNIQQQGHVGNRGTLNAA---RIVVDA--------- 429
Q+SL S+ +++N G + +A +L +Q G V N L A R++ DA
Sbjct 974 G-GQISLTSRGDINNRGFVGAAGDLLLQAIGAVNNTSLLYAGGSMRLLADAIYNVRGDIL 1032
Query 430 -----------------GSLANSGSIEQTGAQALDLKAGSMSNIGGKIGIAKTSSTGGNG 472
+ +SG+IE Q D+ + S + + G + T TG
Sbjct 1033 AGNHLWMQRDNAGNSNREIINSSGNIE---TQQGDMVLNTASLLNRRDGFSVTEKTGAVN 1089
Query 473 SE------------SGGGSQPVEPNNAAQD------GGSLEVVNT-DSTPTTPKT-YETG 512
S S G +P E + ++ G++ VN P+ K T
Sbjct 1090 SGGIANVGATNILISSGYFKPGEVTHYSKTVTGGGHHGNVSTVNLLGLVPSARKQKLSTS 1149
Query 513 YIHVRDQLNNDQGAIVAQGGIDLESNNGLDNQGGQLNLGR-VKIQGERFNNDQGQL-TVK 570
V D G IVA I++ +N L NQ Q++ GR +QG+ NN Q T+
Sbjct 1150 SSIVTVDSPYDVGRIVAGRDINISANT-LVNQASQMSAGRNALLQGQSLNNQSYQSGTLT 1208
Query 571 QAEIQTNSL-SNQSGQLISNQKLNIQTQTANNQ----KGKIQSVDQLDLNVANGLNNIEG 625
Q + TN+ +N L + T +N +G IQ+V + N L+N
Sbjct 1209 QYLVYTNTRDTNPEYNLFEFKLSGSPTYEISNDGQLYQGVIQAVGSVSANFTQNLSNTSV 1268
Query 626 QIASGQQLNIQADQVNNQSGLIYSEQQGIELKANHAI------NNTSGIIQAKTQLNLAS 679
+ G ++ QV S + + K N +N ++ Q A
Sbjct 1269 KPNIGSIVH----QVTQPSLTATTVPSELATKPNSGAAQVAPDSNNGDLVALYNQSGTAL 1324
Query 680 TQLDNTSGHIQAENIQQQHTTVNNTQGSIVAGQS-----LISTVDQFDNHQGLIDA---- 730
T T G + ++ G V LIST + G +D+
Sbjct 1325 TFGLGTDGKPLTRAQLSDYPLPDSNNGLFVVNSEPGSRYLISTNPTLEK-LGNVDSTLLS 1383
Query 731 -----------------KNIQLTHQVLNNSGSIYADQNIKITGQHILNTGSIAAGQNIQL 773
+N Q T Q N GS Y + I + +H AA +
Sbjct 1384 GLQAMLGRQPQTSVAIERNPQWTQQD-NFLGSDYLLKKINLDAEHDYRFLGDAAFDTRYI 1442
Query 774 NTAKL-QHEQAALIAAGLD-------------RQGKLTSTGDLDITAEQTT--------- 810
N A L Q Q L G D Q KL + +T EQ
Sbjct 1443 NNAVLSQTGQRYLNGVGSDLSQMQYLLDNAAQSQKKLDLKLGVSLTPEQVAQLSHSIVWW 1502
Query 811 ----LHGQSFAGQQLKVASKQQIDATNGQLQAKNIDLASDAGDISTRAATVIAEQLSLKS 866
++GQ+ +L +A +Q + ++L +AG ++ E L++ S
Sbjct 1503 ENINVNGQTVLAPKLYLAKAEQAHLQGSVISGNKVEL--NAGSVTNSGVLKGVELLAIAS 1560
Query 867 HDLIDNQQGTLSAQQ--LNLTA-NRLDNTQGHILH-----TGQDQLDLNFSQSLNNQLGE 918
D I N++G L + LNLTA N + N I T Q+ +N +Q+ +
Sbjct 1561 QDTITNEKGGLLTSEGALNLTALNNISNLSSSISGDRVAITSQNGDIINQTQTRQWSADQ 1620
Query 919 IRSNAAELNIKTALLNNTEGQVVHAGTQQLNIQTAQLNGHLGHILSNGTLQLKAGTLDVS 978
R IKT + TE A T + A N +I G AG +
Sbjct 1621 SRQPGYWSGIKTQSMTQTEVGETAAITAGKALTLAAGN----NIAITGAKVTAAGDI--- 1673
Query 979 GGVTSADQITIQANVLNNAQGQLIQRGTSNPLNLTIQQQLNNQA--GLIQSATATDIKAG 1036
G+ +A I I AN L +AQ Q + R + LN + Q ++ + G + + DI
Sbjct 1674 -GIQAAHDINIIANDLYSAQQQTLGRNRNIELNEQHESQSSHVSAGGTLTAHAGRDITLS 1732
Query 1037 SLN---NQRGTLSSAQGQNL----------DVDVAGKLDNSQSGQIYAGNQAHLQVGSID 1083
+ + + TL + + NL +D K + +G G
Sbjct 1733 ASHLGADGNATLQAERDVNLLVQEKSTRNQHIDSEDKTTGYTRSTLSSGGDLTASAGRDI 1792
Query 1084 NSHQGQINAQQNLQLTSQQQIN---------NQS-GQIVANGDVQIQSQGLNNSHGQMGS 1133
NS + A+ L L + + IN N+S G+ D I+ QG + G+
Sbjct 1793 NSQAAAVTAENTLALNAGRDINLNAQESRQYNESHGKNYKRVDEAIRQQGTELASGKGTQ 1852
Query 1134 LQGGLSLNTGSDTLINQSGL-IQAKKDIGIQAQRIDNQQGQITTQGQAELISQAEIDNLE 1192
+ G +N + ++ + L +QA +DI + + + + + +L+S+ I N+E
Sbjct 1853 VHAGQDINLHAASISAKGDLALQAGRDIAVNSATESDYHFFEEKKTKKKLVSKTTIHNVE 1912
Query 1193 GAIAADLDVNIRSQGLNNNKGQISSAQGNLTLNAGNGTLTNQAATIVSGKTLTLSANQLD 1252
D +S L N N++L+AGN + ++ + G + + N +D
Sbjct 1913 ----EDFATTEKSSALVGN---------NVSLSAGNNLIVKGSSVVGDGTVVLKADNNVD 1959
Query 1253 ------NSNHGQINSQNNADISIVKDINNTSGVIAAKQQLILSSQGLNNTTGQIGTVQGN 1306
+ ++N + + + + T G +++QQ+ + + +G+ GN
Sbjct 1960 IVAATEQQSSYRLNEKKTSGMFSGGGLGVTLGSKSSRQQINQEGSKQSESASAVGSTAGN 2019
Query 1307 LHIDAGSQLLNNQQGRIQSGQDLNLNATGIDNTQGQ-ISSKNQLQLDSREQLLNNRQGTL 1365
+ I AG+Q + + +G+DLN+ A I G + + Q+ + L +
Sbjct 2020 VSILAGAQA-HISGSDVIAGKDLNVIAGTIKVDPGNDVLKRRQIYEQKQSGLTLSLSSPF 2078
Query 1366 SAENLTIDS-----GELNNDQ--GLIQAQQSIQIDTHQHNLSNTNSGAQGGILSQGNIQL 1418
+ L I+S + +D+ L AQ + + + + GG + +
Sbjct 2079 TDALLAINSKLKQASDAGSDKLSALYGAQAAREAWVGVDGTMDMMASKPGGPAADPGASI 2138
Query 1419 NNIQTLDNQQGYLASAQQLDLQANQVFNQNGTLLAAKQLNLQGTGQNQLLNNQSGQMLSM 1478
L G S +L NQ + +L A L + +G ++ QSG LS+
Sbjct 2139 K----LQLSVGASHSKSTSELAQNQT--RGSSLTAGDNLTMVASGDHE----QSGD-LSV 2187
Query 1479 GGMNLNIDQINNKGKANTADADSHIMAAGELNITTQQLDNQNTLNTDP-----ANTSIQG 1533
G + +++ K + ++AA N D+ + N T I G
Sbjct 2188 VGSGVTGNKVTLVAKNDV------LLAAASNNSEQTSRDSSSGWNAGVHLSLGKETGI-G 2240
Query 1534 IDANTLNVTSKVLNNQSGVIRSSADQNLNVQQALNNQSGQISSEKQLTLVGDQLEINNLN 1593
I AN SK N G A+ +N ++AL I+S + L G Q+ L
Sbjct 2241 IAAN--GFMSK--GNSDGKTTDYANARINAKEAL-----AINSGRDTVLSGAQV----LG 2287
Query 1594 GQILAGTALDLIAQSLSGDGKLLSL-----------------GNAKLSLQNDYIHSSGAQ 1636
+I A DL SL S+ G+A SL I S A
Sbjct 2288 DKITAEIGRDLTISSLQDSDNYNSIQKDASAGFSFTFGPSGGGSASFSLGKTKIESKYAS 2347
Query 1637 LQANQDLSLSTKGNIINNGTINAGNQLALNAANITNQQAGKIESHDTRLTAQNTLNNTGL 1696
+ +KG +N GN LN + + AQ+ L +TG
Sbjct 2348 VGDQSGFFAGSKG-----FDLNVGNHTQLNGGVLASTAG-----------AQDNLLSTGT 2391
Query 1697 INGDFTRLQAETLNNQGTGRIYGTTLAIQANTL---NNQPDSTGTAPVIASRGDLHLGVQ 1753
+ QAE + T G + TL N ++GT + G+ ++
Sbjct 2392 LGWGDIHNQAE---YKATSTRIGYSTDAPMPTLGMANAHGSASGTTRSAVASGE----IE 2444
Query 1754 TLNNLSNPTDYTSQALIFSAGNLYLGAALDANDYATGQADVIHNESATIESL----GDMN 1809
N D T+ + D A G+ D I +ES + + G
Sbjct 2445 IRNQGEQQQDVTTLS--------------RDTDSANGRIDKIFDESKVKDQMAFTQGVTQ 2490
Query 1810 LSAKQINNINKYFKTEQVEVSRKDGLEK 1837
L+ + + +++ + +Q E S + LEK
Sbjct 2491 LATQLVGDVSSW-NMKQAERSAAEKLEK 2517
Score = 58.5 bits (140), Expect = 2e-10
Identities = 238/1154 (21%), Positives = 439/1154 (38%), Gaps = 238/1154 (21%)
Query 2227 NSVNLKLDGDLINGAT--IAGREALQITADNVQNLNGRIQG---NQVAIETQKDLNN--- 2278
N N+ +G ++N AT + + + N NLNG+ G N+V + LN
Sbjct 67 NQFNVGSEGVILNNATDRLTQTQLGGLIQSNA-NLNGKAAGAIINEVVSANRSQLNGYLE 125
Query 2279 IGGQIIAKDAMALKVG------GNLNIESTTRTSESKVGNFSSSITNVDRVAGLYVGNGS 2332
+GG+ A +A G G +N + T T+ + + + + ++D G G
Sbjct 126 VGGKAAAV-MVANPYGITCDGCGFINTPNVTLTTGKPMMDTNGKLQSLDVTQGAISIQG- 183
Query 2333 TKQLDPNQATLMLNVAGNSSLKGVQINNSNSATVLNTTGNVD-LGTVSV--GKQETLKID 2389
K LD +Q++ L++ ++ QI+ + TV+ + VD G VS G+ + ++
Sbjct 184 -KGLDASQSSA-LSLISRANEINAQIH-AQDLTVIAGSNRVDSAGHVSERQGQGDVPQVS 240
Query 2390 DKNGYQLKQQQDVGSQIKSAGSLLINGQNITSKAVDLNSQQGDIQLSAQKDIVLDNGLNQ 2449
G +G + L+ + + + +LN++QGDIQL ++ + ++N +
Sbjct 241 IDTGA-------LGGMYANRIRLVSSEKGVGVNLGNLNARQGDIQLDSKGKLTVNNAVAH 293
Query 2450 STV---SSQSQSKGSFGGKKSSTYDASSSTSIANQLNAGQNIIINSAQGNISATHLQAEA 2506
+ + Q +G + + T ++ + + N + + A G I++ Q A
Sbjct 294 GDIIASADQLHLQGHQRAQGNITLNSHGESRLDNATLLAGDTLAVKAGGKITSKESQLNA 353
Query 2507 G----NNI----------------QIHAQQGNVTLLSA---IDDKRESSTSSKKGVATYN 2543
G NI Q H V+++S+ + DK S T+ + ++ +
Sbjct 354 GVDSAGNIGEKGTVSLQGSELALQQSHVAAAAVSVVSSGDIVQDKESSLTARQLKLSGQH 413
Query 2544 NRQSGYI----DQEVAQTTLKAGDTVDINAAKNIELQ-ANDVQAGNSIYVGNTLM----Q 2594
+G + D + +L+ T + + KNI A D + + GN L+
Sbjct 414 LELAGQLAANNDLSITGQSLRGSKTASVGSQKNITFNLAGDSEWAGQMVAGNDLIFSGQS 473
Query 2595 RQADGSLKAAD------------GSLMPENVTLSTLATKDEQWDEQQKGYRGIVKDIVKA 2642
G L AA+ G ++ ++ ++ ++ + K +V++
Sbjct 474 LTNHGQLLAANQMHFEGLGLDNQGQILAADINIAVHRLNNQGQLQGDKSLLLTADSLVQS 533
Query 2643 TAVGLAGIEALAPGLKAPKITVS------------ESTGKRTEQISQTGSSLKADNV--- 2687
T + AL L+A ++ +S ++ ++Q + L+ +
Sbjct 534 TRGTMNSGRALT--LRAAEMDISGDLQSQILDVKGDNWHNHGNVVAQEHAQLRLGHTIDN 591
Query 2688 --YVGSSGQTTLTSTDITAKNTILLGQKVTLNAAEEQKITVESTSKETVQGLGAKLNKDS 2745
+ S+G L+ ++ + I LG ++ L S + + G + K
Sbjct 592 RGVLVSAGDMDLSFNQLSNQGRI-LGAELAL-------------SGKNISNSGQLVGKQQ 637
Query 2746 IRLGGFVLEDASQSSKTTE-TTHKLGSINTENLKIQG---VEGVDILGQNITATGDTLID 2801
+ L L++ Q + + E + L S+ + + QG ++ Q +T G L
Sbjct 638 LSL---QLDEGYQGTSSGELKSDGLLSVTADEINNQGHWESGSLNTTAQQLTNNGKVL-S 693
Query 2802 HGRGDLNV-GGYENKTTVEDKTHVETISTEVGVRNAYL---DAALALGAVKDAAEAVKQA 2857
G ++N+ G N+ + T E I V N+ L + A+ L +K
Sbjct 694 VGSQNINLSGSLTNQQLGQFLTDGEFIIVAEQVINSGLLQGNQAVTLNGLK--------- 744
Query 2858 KDQYSQAQRDYASGKITKEALDDSKANVAMATANLANAQIAVGSAAATAAASSATYGFTI 2917
QY K E DS N + I GS + T
Sbjct 745 --QYQGGTGSQLLTKGVGEIHSDSVNNAGL---------IQAGSLSLT------------ 781
Query 2918 GANGERIETTNTTNTTQGKWQGSTLELNNLTLKSENQDVNVQGSRLTATGTTSFDGTKDL 2977
GE ++ T T + STL ++ S N+ +N +L + T D + +
Sbjct 782 ---GEVLDNTGTLSGL------STLHID-----SHNEIINQARGQLLSDNTIKLDSEQLV 827
Query 2978 N--VTAGTE---HSQQETSSKT-------NSQSVSYTYGGGGSASIGKQ---TSTSESKS 3022
N + GTE SQ T++ T Q+V+ T G G+ T++ ++
Sbjct 828 NNGLMQGTELVLASQHLTNNGTLLGLTYLELQAVNLTNSSAGKILSGQDLHFTTSHLQQN 887
Query 3023 LTYVNSEVTLNKTEGRL--NSLNIKGGEVSIQ------DRGNLQVNNIHVESLQDTASSS 3074
+ + +G L + G ++S+Q RGNLQ N++ + S +S
Sbjct 888 GQWTALRDLTGEIKGALDFSGAMAAGKQLSLQVDGDFNQRGNLQGNDVSITSRGVITNS- 946
Query 3075 NSSRGGSIGGGYGSGSKNITASYNQSKGSSDS-AWVNTTSKLLIGN-----AQNDANLDA 3128
G + G GS + N A + GS S ++ TS+ I N A D L A
Sbjct 947 -----GQLAAGSGSLALNGAAINQEQSGSLQSGGQISLTSRGDINNRGFVGAAGDLLLQA 1001
Query 3129 MGVKNITNI---GG---VIANANKNADGSL---------------TDHKNLNYTGNLELK 3167
+G N T++ GG ++A+A N G + ++ + +N +GN+E +
Sbjct 1002 IGAVNNTSLLYAGGSMRLLADAIYNVRGDILAGNHLWMQRDNAGNSNREIINSSGNIETQ 1061
Query 3168 DLQDHNN-----NNSSGFNVSTNIGIPQGGSKAASTAPKGSTTIGLNSSGQ----ETEQL 3218
N N GF+V+ G G A G+T I L SSG E
Sbjct 1062 QGDMVLNTASLLNRRDGFSVTEKTGAVNSG----GIANVGATNI-LISSGYFKPGEVTHY 1116
Query 3219 TKATLGQGSVTNAT 3232
+K G G N +
Sbjct 1117 SKTVTGGGHHGNVS 1130
>Q3YL96 Toxin CdiA [Escherichia coli]
Length=3132
Score = 362 bits (929), Expect = 2e-102
Identities = 381/1420 (27%), Positives = 630/1420 (44%), Gaps = 171/1420 (12%)
Query 107 SSNGVTQVNIQTPSAGGVSRNTYSQFDVGQEGAILNNARNNTQ-TQLGGWIQGNPWL-AK 164
++NGV VNI TP+ G+S N ++ ++VG+EG ILNNA TQLGG IQ NP L A
Sbjct 45 AANGVPVVNIATPNGAGISHNRFTDYNVGKEGLILNNATGKLNPTQLGGLIQNNPNLKAG 104
Query 165 GEAKVILNEVNSSNPSQLKGYIEVAGKQAQVVIANPSGLVCDGCGVINADRFTLTTGQAV 224
GEAK I+NEV S L+GY EVAGK A V++ANP G+ CDGCG IN TLTTG+ V
Sbjct 105 GEAKGIINEVTGGKRSLLQGYTEVAGKAANVMVANPYGITCDGCGFINTPHATLTTGKPV 164
Query 225 MN-QGYLESFRVREGQITIQGKGLNGSLTPFTDVYARALQVNAGLYAKELNVVLGQNDIN 283
MN G L++ V EG ITI G GL+G+ + + ARA +VNA L+AK+L V G N I
Sbjct 165 MNADGSLQALEVTEGSITINGAGLDGTRSDAVSIIARATEVNAALHAKDLTVTAGANRIT 224
Query 284 VNDPTTSNVSPIQSNTSANNKPQFALDVGQLGGMYAGKIFLVGTEQGVGVRNAGSMNSTQ 343
+ VS ++ N P+ A+D G LGGMYA +I L TE GVGV N G++ + +
Sbjct 225 AD----GRVSALKGE---GNVPKVAVDTGALGGMYARRIHLTSTESGVGV-NLGNLYARE 276
Query 344 STLTLNANGDLT-----NTGNLIANQGQLQLNAENIKNTGNIS-SATSQVSLHSQNL--D 395
+ L+++G L GN + L+ +N K GN+S + T+ ++L+ L D
Sbjct 277 GDIILSSSGKLVLKNSLAGGNTTVTGTDVSLSGDN-KAGGNLSVTGTTGLTLNQSRLVTD 335
Query 396 NSGLISSADELNIQQQGHV--GNRGTLNAARIVVDAGSLANSGSIEQTGAQALDLKAGSM 453
+ ++SS+ ++ +Q G + G L+A + +G++ + ++ T LK S
Sbjct 336 KNLVLSSSGQI-VQNGGELTAGQNAMLSAQHLNQTSGTVNAAENVTLTTTDDTTLKGRS- 393
Query 454 SNIGGKIGIAKTSSTGGNGSESGGGSQPVE----PNNAAQDGGSLEVVNTDSTPTTPKTY 509
+ GK + S G+ G V+ N G L+V TD T T
Sbjct 394 --VAGKTLTVSSGSLNNGGTLVAGRDATVKTGTFSNTGTVQGNGLKVTATDLTST----- 446
Query 510 ETGYIHVRDQLNNDQGAIVAQGGIDLESNNG-LDNQGGQLNLGRVKIQGERFNNDQGQLT 568
G+I + +D+ + N L G + V + G N +G+L
Sbjct 447 ---------------GSIKSGSTLDISARNATLSGDAGAKDRALVTVSGTLEN--RGRLV 489
Query 569 VKQAEIQTNSLSNQSGQLISNQKLNIQTQTANNQKGKIQSVDQLDLNVANGLNNIEGQIA 628
+ + N SG L ++L T + + + D +L + + + + G+ +
Sbjct 490 SDDVLTLSATQINNSGTLSGAKELVASADTLTTTEKSVTNSDG-NLMLDSASSTLAGETS 548
Query 629 SGQQLNIQADQV------NNQSGLIYSEQQGIELKANHAINN----------TSGIIQAK 672
+G ++++ + + Q + + Q +L A + T +
Sbjct 549 AGGTVSVKGNSLKTTTTAQTQGNSVSVDVQNAQLDGTQAARDILTLNASEKLTHSGKSSA 608
Query 673 TQLNLASTQLDNTSGHIQAENIQQQHTTVNNTQGSIVAGQSLISTVDQFDNHQG--LIDA 730
L+L++ +L +SG + + Q T+ N+ G + SL + DN Q L A
Sbjct 609 PSLSLSAPEL-TSSGVLVGSALNTQSQTLTNS-GLLQGKASLTVNTQRLDNQQNGTLYSA 666
Query 731 KNIQLTHQVLNNSGSIYADQNIKITGQHILNTGSIAAG----QNIQLNTAKLQHEQAALI 786
++ L + NSG I D + + + N G I A + L+ L AL
Sbjct 667 ADLTLDIPDIRNSGLITGDNGLMLNAVSLSNPGKIIADTLSVRATTLDGDGLLQGAGALA 726
Query 787 AAG----LDRQGKLTSTGDLDITAEQT----TLHGQSFAGQQLKVASKQQIDATNGQLQA 838
AG L G+ + GDL + + T GQ+ Q + A+ + AT G L A
Sbjct 727 LAGDTLSLGSNGRWLTAGDLSLRGKTLHTAGTTQGQNLTVQADRWANSGSVQAT-GNLTA 785
Query 839 KNIDLASDAGDISTRAATVIAEQLSLKSHDLIDNQQGTLSAQQLNLTANRLDNT---QGH 895
+ GDI ++ T + + DN+ LSA L+L N LDN+ QG+
Sbjct 786 SATGQLTSTGDIMSQGDTTLNAATT-------DNRGSLLSAGTLSLDGNSLDNSGTVQGN 838
Query 896 ILH------------TGQDQLDLNFSQSLNNQLGEIRSNAAELNIKTALLNNTEGQVVHA 943
+ TG L L + + + +N L + + L T G + ++
Sbjct 839 HVTIRQNGVTNSGTLTGIAALTLAARMDMASPQPALMNNGGSL-LTSGDLTITAGSLANS 897
Query 944 GT-QQLNIQTAQLNGHL-----GHILSNG------------------TLQLKAGTLDVSG 979
G Q + TA+L G L + SNG L LKA +L +G
Sbjct 898 GAIQAADSLTARLTGELVSTAGSKVTSNGEMALSALNLSNSGQWIAKNLTLKANSLTSAG 957
Query 980 GVTSADQITIQAN--VLNNAQGQLIQRGTSNPLNLTIQQQLNNQAGLIQSATATDIKAGS 1037
+T D +T+ N + N+A G+L+ G LT++ G +Q AT I AG
Sbjct 958 DITGVDALTLTVNQTLNNHASGKLLSAGV-----LTLKADSVKNDGQLQ-GNATTITAGQ 1011
Query 1038 LNNQRGTLSSAQGQNLDVDVAGKLDNSQSGQIYAGNQAHLQVGSIDNSHQGQINAQQNLQ 1097
L N QG+ L + +G ++N G + + N ++ ++ N QG I +
Sbjct 1012 LTNG----GHLQGETLTLAASGGVNNRSGGVLMSRNALNVSTATLSN--QGTIQGGGGVS 1065
Query 1098 LTSQQQINNQSGQIVANGDVQIQSQGLNNSHGQMGSLQGGLSLNTGSDTLINQSGLIQAK 1157
L + ++ N G+I++ ++ + +Q L N+ G +Q L +T+ G + A
Sbjct 1066 LNATDRLQN-DGKILSGSNLTLTAQVLANTGS--GLVQAATLLLDVVNTV--NGGRVLAT 1120
Query 1158 KDIGIQAQRIDNQQGQITTQGQAELISQAEIDNLEGAIAADLDVNIR-SQGLNNNKGQIS 1216
++ ++N T QG L++ N G + + ++ S L N G++
Sbjct 1121 GSADVKGTTLNNTG---TFQGADLLVNYHTFSN-SGTLLGTSGLGVKGSSLLQNGTGRLY 1176
Query 1217 SAQGNLTLNAGNGTLTNQAATIVSGK-TLTLSANQLDNSNHGQINSQNNADISIVKDINN 1275
SA GNL L+A + + Q + +G TL L A +NHG + + ++ + N
Sbjct 1177 SA-GNLLLDAQD--FSGQGQVVATGDVTLKLIAAL---TNHGTLAAGKTLSVTSQNAVTN 1230
Query 1276 TSGVIAAKQQLILSSQGLNNTTGQIGTVQGNLHIDAGSQLLNNQQGRIQSGQDLNLNATG 1335
GV+ ++ + + N G + +GN + + +L N G +Q+G D++LN+
Sbjct 1231 -GGVMQGDAMVLGAGEAFTN-NGTLTAGKGN-SVFSAQRLFLNAPGSLQAGGDVSLNSRS 1287
Query 1336 IDNTQGQISSKNQLQLDSREQLLNNRQGTLSAENLTIDSGELNNDQGLIQAQQSIQIDTH 1395
G + L ++ LLN+ + NL + + L+N G I A S+ +
Sbjct 1288 DITISGFTGTAGSLTMNVAGTLLNSAL-IYAGNNLKLFTDRLHNQHGDILAGNSLWVQKD 1346
Query 1396 QHNLSNTNSGAQGGIL--SQGNIQLNNIQTLDNQQGYLAS 1433
+N+ + G + ++G+I +N L++ AS
Sbjct 1347 SSGTANSEIINRSGNIETTRGDITMNTAHLLNSWDAISAS 1386
Score = 325 bits (832), Expect = 5e-91
Identities = 634/2799 (23%), Positives = 1090/2799 (39%), Gaps = 415/2799 (15%)
Query 543 NQGGQLNLGRVKIQGERFNNDQGQLTVKQAEIQTNSLSNQSGQLISNQKLNIQTQTANNQ 602
N+ N+G+ +G NN G+L Q G LI N N +
Sbjct 65 NRFTDYNVGK---EGLILNNATGKLN-----------PTQLGGLIQN---NPNLKAGGEA 107
Query 603 KGKIQSVDQLDLNVANGLNNIEGQIASGQQLNIQADQVNNQSGLIYSEQQGIELKANHAI 662
KG I V ++ G + G+ A+ N + G + L +
Sbjct 108 KGIINEVTGGKRSLLQGYTEVAGKAANVMVANPYGITCD---GCGFINTPHATLTTGKPV 164
Query 663 NNTSGIIQA----KTQLNLASTQLDNTSGHIQAENIQQQHTTVNNTQGS----IVAGQSL 714
N G +QA + + + LD T A +I + T VN + + AG +
Sbjct 165 MNADGSLQALEVTEGSITINGAGLDGTRS--DAVSIIARATEVNAALHAKDLTVTAGANR 222
Query 715 ISTVDQFDNHQGLIDAKNIQLTHQVLNNSGSIYADQNIKITGQHILNTGSIAAGQNIQLN 774
I+ + +G + + + L G +YA + H+ +T S + +N
Sbjct 223 ITADGRVSALKGEGNVPKVAVDTGAL---GGMYARRI------HLTSTES-----GVGVN 268
Query 775 TAKLQHEQAALIAAGLDRQGKLT-----STGDLDITAEQTTLHGQSFAGQQLKVASKQQI 829
L + +I L GKL + G+ +T +L G + AG L V +
Sbjct 269 LGNLYAREGDII---LSSSGKLVLKNSLAGGNTTVTGTDVSLSGDNKAGGNLSVTGTTGL 325
Query 830 DATNGQLQAKNIDLASDAGDISTRAATVIAEQLSLKSHDLIDNQQGTLSAQQLNLTANRL 889
+L + S +G I + A Q ++ S ++ GT++A + N+T
Sbjct 326 TLNQSRLVTDKNLVLSSSGQIVQNGGELTAGQNAMLSAQHLNQTSGTVNAAE-NVTLTTT 384
Query 890 DNTQGHILHTGQDQLDLNFSQSLNNQLGEIRSNAAELNIKTALLNNTEGQVVHAGTQQLN 949
D+T L ++ S SLNN G + +KT +NT G V G L
Sbjct 385 DDTTLKGRSVAGKTLTVS-SGSLNN--GGTLVAGRDATVKTGTFSNT-GTVQGNG---LK 437
Query 950 IQTAQLNGHLGHILSNGTLQLKAGTLDVSGGVTSADQITIQANVLNNAQGQLIQRGTSNP 1009
+ L G I S TL + A +SG + D+ + + +G+L+
Sbjct 438 VTATDLTS-TGSIKSGSTLDISARNATLSGDAGAKDRALVTVSGTLENRGRLVSDDV--- 493
Query 1010 LNLTIQQQLNNQAGLIQSATATDIKAGSLNNQRGTLSSAQGQNLDVDVAGKLDNSQSGQI 1069
LT+ N +G + A A +L +++++ G NL +D A ++ +G+
Sbjct 494 --LTLSATQINNSGTLSGAKELVASADTLTTTEKSVTNSDG-NLMLDSAS---STLAGET 547
Query 1070 YAGNQAHLQVGSIDNSHQGQINAQ------QNLQLTSQQQIN-----NQSGQIVANGDVQ 1118
AG ++ S+ + Q QN QL Q N S ++ +G
Sbjct 548 SAGGTVSVKGNSLKTTTTAQTQGNSVSVDVQNAQLDGTQAARDILTLNASEKLTHSGKSS 607
Query 1119 IQSQGLNNSHGQMGSLQGGLSLNTGSDTLINQSGLIQAKKDIGIQAQRIDNQQGQITTQG 1178
S L+ + G +LNT S TL N SGL+Q K + + QR+DNQQ T
Sbjct 608 APSLSLSAPELTSSGVLVGSALNTQSQTLTN-SGLLQGKASLTVNTQRLDNQQNG-TLYS 665
Query 1179 QAELISQAEIDNLEGAIAADLDVNIRSQGLNNNKGQISSAQG-NLTLNAGNGTLTNQAAT 1237
A+L G I D + + + L+N I+ T G+G L A
Sbjct 666 AADLTLDIPDIRNSGLITGDNGLMLNAVSLSNPGKIIADTLSVRATTLDGDGLLQGAGAL 725
Query 1238 IVSGKTLTLSANQL-----DNSNHGQI----NSQNNADISIVKDINNTSGVIAAKQQLIL 1288
++G TL+L +N D S G+ + ++++ D SG + A L
Sbjct 726 ALAGDTLSLGSNGRWLTAGDLSLRGKTLHTAGTTQGQNLTVQADRWANSGSVQATGNLTA 785
Query 1289 SSQGLNNTTGQIGTVQGNLHIDAGSQLLNNQQGRIQSGQDLNLNATGIDNT--------- 1339
S+ G +TG I + QG+ ++A + + +G + S L+L+ +DN+
Sbjct 786 SATGQLTSTGDIMS-QGDTTLNAAT---TDNRGSLLSAGTLSLDGNSLDNSGTVQGNHVT 841
Query 1340 --------QGQISSKNQLQLDSREQ-------LLNNRQGTLSAENLTIDSGELNNDQGLI 1384
G ++ L L +R L+NN L++ +LTI +G L N G I
Sbjct 842 IRQNGVTNSGTLTGIAALTLAARMDMASPQPALMNNGGSLLTSGDLTITAGSLANS-GAI 900
Query 1385 QAQQSIQIDTHQHNLSNTNSGAQGGILSQGNIQLNNIQTLDNQQGYLASAQQLDLQANQV 1444
QA S+ +S S + S G + L+ + ++ Q A+ L L+AN +
Sbjct 901 QAADSLTARLTGELVSTAGSK----VTSNGEMALSALNLSNSGQWI---AKNLTLKANSL 953
Query 1445 FNQNGTLLAAKQLNLQGTGQNQLLNNQ-SGQMLSMGGMNLNIDQINNKGKANTADADSHI 1503
+ G + L L NQ LNN SG++LS G + L D + N G+
Sbjct 954 TSA-GDITGVDALTLT---VNQTLNNHASGKLLSAGVLTLKADSVKNDGQ---------- 999
Query 1504 MAAGELNITTQQLDNQNTLNTDPANTSIQG----------IDANTLNVTSKVLNNQSGVI 1553
+ IT QL N L + + G + N LNV++ L+NQ G I
Sbjct 1000 LQGNATTITAGQLTNGGHLQGETLTLAASGGVNNRSGGVLMSRNALNVSTATLSNQ-GTI 1058
Query 1554 RSSADQNLNVQQALNNQSGQISSEKQLTLVGDQLEINNLNGQILAGTALDLIAQSLSGDG 1613
+ +LN L N G+I S LTL Q+ N +G + A T L + +++G G
Sbjct 1059 QGGGGVSLNATDRLQND-GKILSGSNLTLTA-QVLANTGSGLVQAATLLLDVVNTVNG-G 1115
Query 1614 KLLSLGNA--KLSLQNDYIHSSGAQLQANQDL-----------SLSTKGN-IINNGT--- 1656
++L+ G+A K + N+ GA L N L KG+ ++ NGT
Sbjct 1116 RVLATGSADVKGTTLNNTGTFQGADLLVNYHTFSNSGTLLGTSGLGVKGSSLLQNGTGRL 1175
Query 1657 INAGNQL-----------ALNAANITNQQAGKIESHDT-------RLTAQNTLNNTGLIN 1698
+AGN L + ++T + + +H T +T+QN + N G++
Sbjct 1176 YSAGNLLLDAQDFSGQGQVVATGDVTLKLIAALTNHGTLAAGKTLSVTSQNAVTNGGVMQ 1235
Query 1699 GDFTRLQA-ETLNNQGT---GRIYGTTLAIQANTLNNQPDS--TGTAPVIASRGDLHLG- 1751
GD L A E N GT G+ G ++ N P S G + SR D+ +
Sbjct 1236 GDAMVLGAGEAFTNNGTLTAGK--GNSVFSAQRLFLNAPGSLQAGGDVSLNSRSDITISG 1293
Query 1752 -VQTLNNLSNPTDYT--SQALIFSAGNLYL--------------GAALDANDYATGQADV 1794
T +L+ T + ALI++ NL L G +L ++G A+
Sbjct 1294 FTGTAGSLTMNVAGTLLNSALIYAGNNLKLFTDRLHNQHGDILAGNSLWVQKDSSGTANS 1353
Query 1795 -IHNESATIESL-GDMNLS-AKQINNINKYFKTEQV-------------------EVSRK 1832
I N S IE+ GD+ ++ A +N+ + + +V V R
Sbjct 1354 EIINRSGNIETTRGDITMNTAHLLNSWDAISASHEVIPGSSHGVISPVPENNRWWGVVRH 1413
Query 1833 DGLEKYCDAWCTFDGNYYDGNPYEDWMRYYYSEITYETRTTESAPGQIKAGGHLDLNGAQ 1892
DG+E W G D R + T + +I G + + +
Sbjct 1414 DGVEYLAVYWGK-------GATVPDEYRIRTGDTETVTVSASGHAARISGGADMHIRAGR 1466
Query 1893 VVNDKSQILAGGELKNEGGTIDS-----GTQIAGIRKIVNTGTQVKYWKYEGQWDNPFEN 1947
+ N+ S ILAGG + G T+++ GT + +G+ K W E W +
Sbjct 1467 LDNEASFILAGGGMTLSGDTLNNQGWQEGTTGKETVWRLASGSLPKAWFTE-PWYKVYRQ 1525
Query 1948 SSETTFDLS-----------------ISQALGNQNLNQNQLSTVAVSNNQSAEHIQNS-- 1988
S + S +S + N + + N NS
Sbjct 1526 VSPDATEASGTSPAGQYRAVISAAGDVSASFATDTGNTTVMPRAGGAGNTITVPSLNSLT 1585
Query 1989 -QTTQQEINGLQTSNNNTQLNQTKDVDLDQL--NLKDSQSQNAPQASAVETVQQQSATSA 2045
T Q ++G + N + T V D L LKD + ++V + S +
Sbjct 1586 PPTVSQGVSG-EALLNESGTGITGPVWNDALPDTLKDIPGALSLSGASVSSYPLPSGNNG 1644
Query 2046 ---PSSTPQGTSEEIRSIDFSNI-KVPNS---ALYKVNADSKAGYLIETDPAFADYKKWL 2098
PS+ P + + KV +S LY + ETDPA+ D K++L
Sbjct 1645 YFVPSTDPDSPYLITVNPKLDGLGKVDSSLFAGLYDLLRMQPGEAPRETDPAYTDEKQFL 1704
Query 2099 SSDYMLDALGLDPALQQKRLGDGFYEQRLVQDQIANLTGYRFLEGFANDDEQYKALMNNG 2158
S Y+LD LGL P + LGD ++ R V + I N TG R++ G +D Q K LM++
Sbjct 1705 GSSYILDRLGLKPEKDYRFLGDAAFDTRYVSNVILNQTGSRYINGTGSDLAQMKYLMDSA 1764
Query 2159 ITFAKLYGLRPGIALTAAQTAQLTSDIVWLVEQSVTLPDGTITKALVPQVYVKVRVGDLK 2218
K GL G++LTA Q AQLT ++W +SVT+ T+ +VP++Y+ L
Sbjct 1765 AAQQKALGLTFGVSLTAGQVAQLTRSLLWW--ESVTINGQTV---MVPKLYLSPEDITLH 1819
Query 2219 GDGTLLSGNSVNLKLDGDLINGATI-AGREALQITADNVQNLNGRI--QGNQVAIETQKD 2275
+G+++SGN+V L +G++I A + L ++ NLN + G + ++ D
Sbjct 1820 -NGSVISGNNVQLAGGNITNSGSSINAQNDLLLDRTGSIDNLNAGLINAGGALNLKAIGD 1878
Query 2276 LNNIGGQIIAKDAMALKVGGNLNIESTTRTSESKVGNFSSSITNVDRVAGLYVGNGSTKQ 2335
+ NI I K G NI + TRT + + N + + D T
Sbjct 1879 IGNISSVISGKTVSLESATG--NISNLTRTEQWAMNNGYNHFSGTD-----------TGP 1925
Query 2336 LDPNQAT--LMLNVAGNSSLKGVQINNSNSATVLNTTGNVDLGTVSVGKQETLKIDDKNG 2393
L +AT L + AG+ S+ G ++ +S VL GN DL ++ E +
Sbjct 1926 LAAVRATDSLFMGAAGDISITGAAVSAGDS--VLLAAGN-DLNMNAIQAGERRRYGGSGW 1982
Query 2394 YQLKQQQDVGSQIKSAGSLLINGQNITSKAVDLNSQQGDIQLSAQKDIVLDNGLNQSTVS 2453
Y + V + + SL++ S D+NSQ I DI +N ++
Sbjct 1983 Y---ETHAVAPTVTAGNSLML------SAGRDVNSQAAGITAENSMDIRAGRDVN---MA 2030
Query 2454 SQSQSKGSFGGKKSSTYDASSSTSIANQLNAGQNIIINSAQGNISATHLQAEAGNNIQIH 2513
++S G S S + +G +I + + + +I++ A +I+++
Sbjct 2031 AESTGAGDHDSTFSMKTVHDSVRQQGTDMTSGGDITVTAGR-DITSVATAVTAKGDIRVN 2089
Query 2514 AQQGNVTLLSAIDDKRESSTSSKKGVATYNNRQSGYIDQEVA---QTTLKAGDTVDINAA 2570
A ++ L +A + S S + +++ + I ++ + +L +G+ V +NA
Sbjct 2090 AGH-DIVLGTATESDYHYSESGETRNRLLSHQTTRTITEDSVTREKGSLLSGNRVTVNAG 2148
Query 2571 KNIELQANDVQAGNSIYVGNTLMQRQADGSLKAADGSLMPENVTLSTLATKDEQWDEQQK 2630
N+ +Q +DV A + + AAD +V + + D W ++
Sbjct 2149 NNLTVQGSDVVADRDVSL--------------AAD-----NHVDVLAATSTDTSWRFKE- 2188
Query 2631 GYRGIVKDIVKATAVGLAGIEALAPGLKAPKITVSESTGKRTEQISQTGSSLKADNVYVG 2690
GL G + + K T T+ S + A NV +
Sbjct 2189 -----------TKTSGLTGTGGIGFTTGSSKTTHDRREAGTTQSQSASTIGSTAGNVSIT 2237
Query 2691 SSGQTTLTSTDITAKNTI-LLGQKVTLNAAEEQKITVESTSKETVQGLGAKLNKDSIRLG 2749
+ Q ++ +D+ A I + G V ++ +++ TV+ ++ GL L S +G
Sbjct 2238 AGKQAHISGSDVIANRDISITGDSVVVDPGHDRR-TVDEKFEQKKSGLTVAL---SGAVG 2293
Query 2750 GFVLEDASQSSKTTETT-HKLGSINTENLKIQGVE-GVDILGQNITATGDTLIDHGRG-D 2806
+ + + + ET+ +L ++ + GV+ GV+ Q +A ++G G
Sbjct 2294 SAINNAVTMAREAKETSDSRLAALKGTQAVLSGVQAGVNHGLQQQSADP----NNGIGVS 2349
Query 2807 LNVGGYENKTTVEDKTHVETISTEVGVRNAYLDAALALGAVKDAAEAVKQAKDQYSQAQR 2866
+++ ++K+ + + + + ST N + A G KD ++ +
Sbjct 2350 ISLNHQQSKSETKYQHDIVSGSTLSAGNNV---SVTATGKNKD-----------HNNSGD 2395
Query 2867 DYASGKITKEALDDS-KANVAMATANLANAQIAVGSAAATAAASSATYGFTIGANGERIE 2925
+G K D S A + A A+ + G ++ ++G G NG +
Sbjct 2396 MLITGSQIKSGNDTSLNAQNDILLAAAADTRQTTGKNSSKGGGVGVSFGG--GTNGGGLS 2453
Query 2926 TTNTTNTTQGK-------WQGSTLELNNLTLKSENQDVNVQGSRLTATGTTSFDGTKDLN 2978
N ++G+ W +TL+ + +D + G++++ T+ D +L
Sbjct 2454 IFAGINGSEGREKGNGTTWTETTLDAGKNVSLTSGRDTTLSGAQVSGEKVTA-DVGNNLT 2512
Query 2979 VTAGTEHSQQETSSKTNSQSVSYTYG---GGGSASIGKQTSTSESKSL-----TYVNSEV 3030
+++ + + ++ + S+T+G G G ASI + S S+ Y +
Sbjct 2513 ISSLQDSDRYDSRQNRVAAGGSFTFGSMSGSGYASISQDKIKSNYDSVREQSGIYAGKD- 2571
Query 3031 TLNKTEGRLNSLN-IKGGEVSIQDRGNLQVNNIHVESLQDTASSSNSSRGGSIGGGYGSG 3089
+ T G LN + D+ +L N + + + A S G S+ GG G
Sbjct 2572 GFDVTVGNHTQLNGAVIASTATDDKNSLNTNTLGWSDIHNQADYKASHTGISLSGGSGMS 2631
Query 3090 SKNITAS---------YNQSKGSSDSAWVNTTSKLLIGN 3119
+ + AS GSS A T+S + GN
Sbjct 2632 ASQMVASNAIAGAANALTGMSGSSGHAEGTTSSAISGGN 2670
Score = 82.8 bits (203), Expect = 1e-17
Identities = 202/957 (21%), Positives = 358/957 (37%), Gaps = 154/957 (16%)
Query 742 NSGSIYADQNIKITGQHILNTGSIAAGQNIQL--NTAKLQHEQAALIAAGLDRQGK-LTS 798
++GS+ + N+++ G +I N+GS QN L T + + A LI AG K +
Sbjct 1819 HNGSVISGNNVQLAGGNITNSGSSINAQNDLLLDRTGSIDNLNAGLINAGGALNLKAIGD 1878
Query 799 TGDLDITAEQTTLHGQSFAGQQLKVASKQQIDATNGQLQAKNIDL-------ASD----- 846
G++ T+ +S G + +Q NG D A+D
Sbjct 1879 IGNISSVISGKTVSLESATGNISNLTRTEQWAMNNGYNHFSGTDTGPLAAVRATDSLFMG 1938
Query 847 -AGDISTRAATVIAEQLSLKSHDLIDNQQGTLSAQQLNLTANRLDNTQGHI-LHTGQDQL 904
AGDIS A V A L + N + ++ + T T + L
Sbjct 1939 AAGDISITGAAVSAGDSVLLAAGNDLNMNAIQAGERRRYGGSGWYETHAVAPTVTAGNSL 1998
Query 905 DLNFSQSLNNQLGEIRSNAAELNIKTALLNNTEGQVVHAGTQQLNIQTAQLNGHLGHILS 964
L+ + +N+Q I + + ++I+ N + AG T + +
Sbjct 1999 MLSAGRDVNSQAAGITAENS-MDIRAGRDVNMAAESTGAGDHD---STFSMKTVHDSVRQ 2054
Query 965 NGTLQLKAGTLDVSGG--VTS-ADQITIQANVLNNAQGQLIQRGTSNPLNLTIQQQLNNQ 1021
GT G + V+ G +TS A +T + ++ NA G I GT+ + + +
Sbjct 2055 QGTDMTSGGDITVTAGRDITSVATAVTAKGDIRVNA-GHDIVLGTATESDYHYSESGETR 2113
Query 1022 AGLIQSATATDIKAGSLNNQRGTLSSAQ------GQNLDV---DVAGKLDNSQSGQIYAG 1072
L+ T I S+ ++G+L S G NL V DV D S + A
Sbjct 2114 NRLLSHQTTRTITEDSVTREKGSLLSGNRVTVNAGNNLTVQGSDVVADRDVS----LAAD 2169
Query 1073 NQAH-LQVGSIDNSHQGQINAQQNLQLTSQQQINNQSGQIVANGDVQIQSQGLNNSHGQM 1131
N L S D S + + LT I +G D + + S +
Sbjct 2170 NHVDVLAATSTDTS--WRFKETKTSGLTGTGGIGFTTGSSKTTHDRREAGTTQSQSASTI 2227
Query 1132 GSLQGGLSLNTGSDTLINQSGLIQAKKDIGIQAQRIDNQQGQ------------------ 1173
GS G +S+ G I+ S +I A +DI I + G
Sbjct 2228 GSTAGNVSITAGKQAHISGSDVI-ANRDISITGDSVVVDPGHDRRTVDEKFEQKKSGLTV 2286
Query 1174 -------------ITTQGQAELISQAEIDNLEG------AIAADLDVNIRSQGLNNNKG- 1213
+T +A+ S + + L+G + A ++ ++ Q + N G
Sbjct 2287 ALSGAVGSAINNAVTMAREAKETSDSRLAALKGTQAVLSGVQAGVNHGLQQQSADPNNGI 2346
Query 1214 --------QISSAQ--------GNLTLNAGNG---TLTNQAATIVSGKTLTLSANQLDNS 1254
Q S ++ TL+AGN T T + + + ++ +Q+ +
Sbjct 2347 GVSISLNHQQSKSETKYQHDIVSGSTLSAGNNVSVTATGKNKDHNNSGDMLITGSQIKSG 2406
Query 1255 NHGQINSQNNADISIVKDINNTSGVIAAKQQLILSSQGLNNTTGQIGTVQGNLHIDAGSQ 1314
N +N+QN+ ++ D T+G ++K G+ + G GT G L I AG
Sbjct 2407 NDTSLNAQNDILLAAAADTRQTTGKNSSK------GGGVGVSFGG-GTNGGGLSIFAG-- 2457
Query 1315 LLNNQQGRIQSGQDLNLNATGIDNTQGQISSKNQLQLDSREQLLNNRQGTLSAENLTIDS 1374
+N +GR + G T +D + KN R+ L+ Q +S E +T D
Sbjct 2458 -INGSEGR-EKGNGTTWTETTLD------AGKNVSLTSGRDTTLSGAQ--VSGEKVTADV 2507
Query 1375 GELNNDQGLIQAQQSIQIDTHQHNLS-------NTNSGAQGGILSQGNIQLNNIQTLDNQ 1427
G N+ + Q S + D+ Q+ ++ + SG+ +SQ I+ +N ++ Q
Sbjct 2508 G---NNLTISSLQDSDRYDSRQNRVAAGGSFTFGSMSGSGYASISQDKIK-SNYDSVREQ 2563
Query 1428 QGYLASAQQLDLQANQVFNQNGTLLAAKQLNLQGTGQNQLLNNQSGQMLSMGGMNLNIDQ 1487
G A D+ NG ++A+ T LN + L
Sbjct 2564 SGIYAGKDGFDVTVGNHTQLNGAVIAS-----TATDDKNSLNTNT----------LGWSD 2608
Query 1488 INNKGKANTADADSHIMAAGELNITTQQLDNQNTL-NTDPANTSIQGIDANTLNVTSKVL 1546
I+N +A+ + + I +G ++ Q+ N + A T + G + TS +
Sbjct 2609 IHN--QADYKASHTGISLSGGSGMSASQMVASNAIAGAANALTGMSGSSGHAEGTTSSAI 2666
Query 1547 NNQSGVIRSSADQNLNV---QQALNNQSGQIS----SEKQLTLVGDQLEINNLNGQI 1596
+ + +IR+ Q ++ + N +G I+ EK+ + + I+ ++GQ+
Sbjct 2667 SGGNLIIRNKESQKQDIAGLSRDPENANGSIAPIFDREKEQKRLQEAQVISQISGQM 2723
Score = 67.8 bits (164), Expect = 4e-13
Identities = 204/1051 (19%), Positives = 374/1051 (36%), Gaps = 113/1051 (11%)
Query 2217 LKGDGTLLSGNSVNLKLDGDLINGATIAGREALQITADNVQNLNGRIQGNQVAIETQKDL 2276
++ G L +G + L T+ E + +T + L GR + + L
Sbjct 347 VQNGGELTAGQNAMLSAQHLNQTSGTVNAAENVTLTTTDDTTLKGRSVAGKTLTVSSGSL 406
Query 2277 NNIGGQIIAKDAMALKVGGNLNIESTTRTSESKVGNFSSSITNVDRVAGLYVGNGSTKQL 2336
NN G + +DA +++ T ++ V +T D + + +GST +
Sbjct 407 NNGGTLVAGRDA---------TVKTGTFSNTGTVQGNGLKVTATDLTSTGSIKSGSTLDI 457
Query 2337 DPNQATL----------MLNVAGNSSLKGVQINN---SNSATVLNTTGNVDLGTVSVGKQ 2383
ATL ++ V+G +G +++ + SAT +N +G + V
Sbjct 458 SARNATLSGDAGAKDRALVTVSGTLENRGRLVSDDVLTLSATQINNSGTLSGAKELVASA 517
Query 2384 ETLKIDDK-------NGYQLKQQQDVGSQIKSAGSLLINGQNI---TSKAVDLNSQQGDI 2433
+TL +K N + + + G++ + G ++ T+ NS D+
Sbjct 518 DTLTTTEKSVTNSDGNLMLDSASSTLAGETSAGGTVSVKGNSLKTTTTAQTQGNSVSVDV 577
Query 2434 Q------LSAQKDIVLDNGLNQSTVSSQSQSKGSFGGKKSSTYDASSSTSIANQLNAGQN 2487
Q A +DI+ N + T S +S + S+ SS + + LN
Sbjct 578 QNAQLDGTQAARDILTLNASEKLTHSGKSSAPSL---SLSAPELTSSGVLVGSALNTQSQ 634
Query 2488 IIINSA--QGNISATHLQAEAGNNIQIHAQQGNVTLLSAIDDKRESSTSSKKGVATYNNR 2545
+ NS QG S T N Q Q N TL SA D + G+ T +N
Sbjct 635 TLTNSGLLQGKASLT-------VNTQRLDNQQNGTLYSAADLTLDIPDIRNSGLITGDN- 686
Query 2546 QSGYIDQEVAQTT--LKAGDTVDINAAKNIELQANDVQAGNSIYVGNTLMQRQADGSLKA 2603
G + V+ + DT+ + A ++ AG G+TL L A
Sbjct 687 --GLMLNAVSLSNPGKIIADTLSVRAT-TLDGDGLLQGAGALALAGDTLSLGSNGRWLTA 743
Query 2604 ADGSLMPENV-TLSTLATKDEQWDEQQKGYRGIVKDIVKATAVGLAGIEALAPGLKAPKI 2662
D SL + + T T ++ + G V+ TA + + +
Sbjct 744 GDLSLRGKTLHTAGTTQGQNLTVQADRWANSGSVQATGNLTASATGQLTSTGDIMSQGDT 803
Query 2663 TVSESTGKRTEQISQTGSSLKADNVYVGSSG-----QTTLTSTDITAKNTILLGQKVTLN 2717
T++ +T + G +L D + +SG T+ +T T+ +TL
Sbjct 804 TLNAATTDNRGSLLSAG-TLSLDGNSLDNSGTVQGNHVTIRQNGVTNSGTLTGIAALTLA 862
Query 2718 AAEEQKITVESTSKETVQGLGAKLNKDSIRLGGFVLEDASQSSKTTETTHKLGS--INTE 2775
A ++ + S + G+ L + + L ++ T +L ++T
Sbjct 863 A----RMDMASPQPALMNNGGSLLTSGDLTITAGSLANSGAIQAADSLTARLTGELVSTA 918
Query 2776 NLKIQGVEGVDILGQNITATGDTLIDHGRGDLNVGGYENKTTVEDKTHVETISTEVG--V 2833
K+ + + N++ +G + + N + T+ D T V+ ++ V +
Sbjct 919 GSKVTSNGEMALSALNLSNSGQWIAKNLTLKAN-----SLTSAGDITGVDALTLTVNQTL 973
Query 2834 RNAYLDAALALGAVKDAAEAVKQAKDQYSQAQRDYASGKITKEALDDSKANVAMATANLA 2893
N L+ G + A++VK Q +G++T + A+ +
Sbjct 974 NNHASGKLLSAGVLTLKADSVKN-DGQLQGNATTITAGQLTNGGHLQGETLTLAASGGVN 1032
Query 2894 NAQIAV---GSAAATAAASSATYGFTIGANGERIETTNTTNTTQGKWQGSTLELNNLTLK 2950
N V +A + A+ + G G G + T+ GS L L L
Sbjct 1033 NRSGGVLMSRNALNVSTATLSNQGTIQGGGGVSLNATDRLQNDGKILSGSNLTLTAQVLA 1092
Query 2951 SENQDV------------NVQGSRLTATGTTSFDGTKDLNVTAGTEHSQQETSSKT--NS 2996
+ + V G R+ ATG+ GT LN T + + + T NS
Sbjct 1093 NTGSGLVQAATLLLDVVNTVNGGRVLATGSADVKGT-TLNNTGTFQGADLLVNYHTFSNS 1151
Query 2997 QSVSYTYGGGGSASIGKQTSTSESKSLTYVNSEVTLNKTEGRLNSLNIKGGEVSIQ---- 3052
++ T G G S Q T Y + L+ + + G+V+++
Sbjct 1152 GTLLGTSGLGVKGSSLLQNGTGR----LYSAGNLLLDAQDFSGQGQVVATGDVTLKLIAA 1207
Query 3053 --DRGNLQVNNIHVESLQDTASSSNSSRGGSIGGGYGSGSKN---ITASYNQSKGSSDSA 3107
+ G L + Q+ ++ +G ++ G G N +TA S S+
Sbjct 1208 LTNHGTLAAGKTLSVTSQNAVTNGGVMQGDAMVLGAGEAFTNNGTLTAGKGNSVFSAQRL 1267
Query 3108 WVNTTSKLLIGNAQNDANLDAMGVKNITNIGGVIANANKNADGSLTDHKNLNYTGNLELK 3167
++N L G D +L++ I+ G + N G+L + L Y GN LK
Sbjct 1268 FLNAPGSLQAG---GDVSLNSRSDITISGFTGTAGSLTMNVAGTLL-NSALIYAGN-NLK 1322
Query 3168 DLQDHNNNNSSGFNVSTNIGIPQGGSKAAST 3198
D +N ++ + + S A++
Sbjct 1323 LFTDRLHNQHGDILAGNSLWVQKDSSGTANS 1353
Score = 61.6 bits (148), Expect = 3e-11
Identities = 195/934 (21%), Positives = 349/934 (37%), Gaps = 144/934 (15%)
Query 531 GGIDLESNNGLDNQGGQLNLGRVKIQGERFNNDQGQLTVKQAEIQTNSLSN--QSGQLIS 588
G ID N GL N GG LNL + G + G+ E T ++SN ++ Q
Sbjct 1855 GSID-NLNAGLINAGGALNLKAIGDIGNISSVISGKTV--SLESATGNISNLTRTEQWAM 1911
Query 589 NQKLNIQTQTANNQKGKIQSVDQLDLNVANGLNNIEGQIASGQQLNIQADQVNNQSGLIY 648
N N + T +++ D L + A ++ +++G + + A N + +
Sbjct 1912 NNGYNHFSGTDTGPLAAVRATDSLFMGAAGDISITGAAVSAGDSVLLAAGNDLNMNAIQA 1971
Query 649 SEQQ---GIELKANHAINNTSGIIQAKTQLNLASTQLDNTSGHIQAENIQ--QQHTTVNN 703
E++ G HA+ T + + + A +++ + I AEN + VN
Sbjct 1972 GERRRYGGSGWYETHAVAPT--VTAGNSLMLSAGRDVNSQAAGITAENSMDIRAGRDVNM 2029
Query 704 TQGSIVAGQSLISTVDQFDNHQGLIDAKNIQLTHQVLNNSGSIYADQNIKITGQHILNTG 763
S AG D + + + D+ Q T ++ A ++I + G
Sbjct 2030 AAESTGAGDH-----DSTFSMKTVHDSVRQQGTDMTSGGDITVTAGRDITSVATAVTAKG 2084
Query 764 SIA--AGQNIQLNTAKLQ----HEQAALIAAGLDRQGKLTSTGDLDITAEQTTLHGQSF- 816
I AG +I L TA E L Q T T D + + L G
Sbjct 2085 DIRVNAGHDIVLGTATESDYHYSESGETRNRLLSHQTTRTITEDSVTREKGSLLSGNRVT 2144
Query 817 --AGQQLKVASKQQIDATNGQLQAKN-ID-LASDAGDISTRAATVIAEQL---------- 862
AG L V + + L A N +D LA+ + D S R L
Sbjct 2145 VNAGNNLTVQGSDVVADRDVSLAADNHVDVLAATSTDTSWRFKETKTSGLTGTGGIGFTT 2204
Query 863 --SLKSHDLIDNQQGTLSAQQLNLTANRLDNTQGHILHTGQDQLDLNFSQSLNNQLGEIR 920
S +HD + GT +Q +A+ + +T G++ T Q ++ S + N+ I
Sbjct 2205 GSSKTTHD--RREAGTTQSQ----SASTIGSTAGNVSITAGKQAHISGSDVIANRDISIT 2258
Query 921 SNAAELNIKTALLNNTEGQVVHAGTQQLNIQTAQLNGHLGHILSNGTLQLKAG--TLDVS 978
++ ++ + V Q+ + T L+G +G ++N + T D
Sbjct 2259 GDSVVVD-----PGHDRRTVDEKFEQKKSGLTVALSGAVGSAINNAVTMAREAKETSDSR 2313
Query 979 GGVTSADQIT---IQANVLNNAQGQLIQRGTSNPLN-LTIQQQLNNQAGLIQSATATDIK 1034
Q +QA V + Q Q +++P N + + LN+Q ++ DI
Sbjct 2314 LAALKGTQAVLSGVQAGVNHGLQQQ-----SADPNNGIGVSISLNHQQSKSETKYQHDIV 2368
Query 1035 AGSLNNQRGTLSSAQGQNLDVDVAGK-LDNSQSG-QIYAGNQAHLQVGSIDNSHQGQINA 1092
+GS TLS+ G N+ V GK D++ SG + G+Q I + + +NA
Sbjct 2369 SGS------TLSA--GNNVSVTATGKNKDHNNSGDMLITGSQ-------IKSGNDTSLNA 2413
Query 1093 QQNLQLTSQQQINNQSGQIVA-------------NGDVQIQSQGLNNSHGQ--------- 1130
Q ++ L + +G+ + NG G+N S G+
Sbjct 2414 QNDILLAAAADTRQTTGKNSSKGGGVGVSFGGGTNGGGLSIFAGINGSEGREKGNGTTWT 2473
Query 1131 MGSLQGG--LSLNTGSDTLINQSGLIQAK--KDIG--------IQAQRIDNQQGQITTQG 1178
+L G +SL +G DT ++ + + K D+G + R D++Q ++ G
Sbjct 2474 ETTLDAGKNVSLTSGRDTTLSGAQVSGEKVTADVGNNLTISSLQDSDRYDSRQNRVAAGG 2533
Query 1179 QAELISQAEIDNLEGAIAADLDVNIRSQGLNNNKGQISSAQG------NLTLNAGNGTLT 1232
G+++ +I + +N + G + GN T
Sbjct 2534 SFTF----------GSMSGSGYASISQDKIKSNYDSVREQSGIYAGKDGFDVTVGNHTQL 2583
Query 1233 NQAATIVSGKTLTLSANQLDNSNHGQINSQNNAD-------ISIVKDINNTSGVIAAKQQ 1285
N A V T T N L+ + G + N AD IS+ ++ + A
Sbjct 2584 NGA---VIASTATDDKNSLNTNTLGWSDIHNQADYKASHTGISLSGGSGMSASQMVASNA 2640
Query 1286 LILSSQGLNNTTGQIGTVQGNLH--IDAGSQLLNNQQGRIQSGQDLNLNATGIDNTQGQI 1343
+ ++ L +G G +G I G+ ++ N++ + Q L+ + + + I
Sbjct 2641 IAGAANALTGMSGSSGHAEGTTSSAISGGNLIIRNKESQKQDIAGLSRDPENANGSIAPI 2700
Query 1344 SSKNQLQLDSRE-QLLNNRQGTLSAENLTIDSGE 1376
+ + Q +E Q+++ G +S N+ + GE
Sbjct 2701 FDREKEQKRLQEAQVISQISGQMS--NIVMTYGE 2732
Score = 59.3 bits (142), Expect = 1e-10
Identities = 182/873 (21%), Positives = 310/873 (36%), Gaps = 158/873 (18%)
Query 2413 LINGQNITSKAVDL---NSQQGDIQLSAQKDIVLDNGLNQSTVSSQSQSKGSFGGKKSST 2469
L NG I+ V L N ++AQ D++LD T S + + G +
Sbjct 1818 LHNGSVISGNNVQLAGGNITNSGSSINAQNDLLLDR-----TGSIDNLNAGLINAGGALN 1872
Query 2470 YDASSSTSIANQLNAGQNIIINSAQGNIS-ATHLQAEAGNNIQIHAQQGNVTLLSAIDDK 2528
A + + +G+ + + SA GNIS T + A NN H + L+A+
Sbjct 1873 LKAIGDIGNISSVISGKTVSLESATGNISNLTRTEQWAMNNGYNHFSGTDTGPLAAV--- 1929
Query 2529 RESSTSSKKGVATYNNRQSGYIDQEVAQTTLKAGDTVDINAAKNIELQANDVQAGNSI-Y 2587
++ S G A D + + AGD+V + A ++ + A +QAG Y
Sbjct 1930 -RATDSLFMGAAG---------DISITGAAVSAGDSVLLAAGNDLNMNA--IQAGERRRY 1977
Query 2588 VGNTLMQRQADGSLKAADGSLMPENVTLSTLATKDEQWDEQQKGYRGIVKDIVKATAVGL 2647
G+ + A A SLM A +D V + A G+
Sbjct 1978 GGSGWYETHAVAPTVTAGNSLMLS-------AGRD-----------------VNSQAAGI 2013
Query 2648 AGIEALAPGLKAPKITVSESTGKRTEQISQTGSSLKADNVYVGSSGQTTLTSTDITAKNT 2707
++ +ESTG + S+K + V G + DIT
Sbjct 2014 TAENSMDIRAGRDVNMAAESTGAGDHDST---FSMKTVHDSVRQQGTDMTSGGDIT---- 2066
Query 2708 ILLGQKVTLNAAEEQKITVESTSKETVQGLGAKLNKDSIRLGGFVLEDASQSSKTTETTH 2767
+ G+ +T + T+K + ++N + G E S++ ET +
Sbjct 2067 VTAGRDIT-------SVATAVTAKGDI-----RVNAGHDIVLGTATESDYHYSESGETRN 2114
Query 2768 KLGSINTENLKIQGVEGVDILGQNITATGDTLIDHGRGDLNVGGYENKTTVEDKTHVETI 2827
+L S T I ++T +L+ R +N G N TV+ V
Sbjct 2115 RLLSHQTTRT---------ITEDSVTREKGSLLSGNRVTVNAG---NNLTVQGSDVVADR 2162
Query 2828 STEVGVRNAYLDAALALGAVKDAAEAVKQAKDQYSQAQRDYA----SGKIT---KEALDD 2880
+ N ++D A D + K+ K S K T +EA
Sbjct 2163 DVSLAADN-HVDVLAATST--DTSWRFKETKTSGLTGTGGIGFTTGSSKTTHDRREAGTT 2219
Query 2881 SKANVAMATANLANAQIAVGSAAATAAASS-ATYGFTIGANGERIETTNTTNTTQGKWQ- 2938
+ + + N I G A + + A +I + ++ + T K++
Sbjct 2220 QSQSASTIGSTAGNVSITAGKQAHISGSDVIANRDISITGDSVVVDPGHDRRTVDEKFEQ 2279
Query 2939 ---GSTLELNNLTLKSENQDVNV--QGSRLTATGTTSFDGTKDL--NVTAGTEHSQQETS 2991
G T+ L+ + N V + + + + + GT+ + V AG H Q+ S
Sbjct 2280 KKSGLTVALSGAVGSAINNAVTMAREAKETSDSRLAALKGTQAVLSGVQAGVNHGLQQQS 2339
Query 2992 SKTNSQSVSYTYGGGGSASIGKQTSTSESKSLTYVNSEVTL-------------NKTEGR 3038
+ N+ G G S S+ Q S SE+K + S TL NK
Sbjct 2340 ADPNN-------GIGVSISLNHQQSKSETKYQHDIVSGSTLSAGNNVSVTATGKNKDHNN 2392
Query 3039 LNSLNIKGGEVSIQDRGNLQV-NNIHVESLQDTASSS--NSSRGG----SIGGGYGSGSK 3091
+ I G ++ + +L N+I + + DT ++ NSS+GG S GGG G
Sbjct 2393 SGDMLITGSQIKSGNDTSLNAQNDILLAAAADTRQTTGKNSSKGGGVGVSFGGGTNGGGL 2452
Query 3092 NITASYNQSKG---SSDSAWVNTTS------KLLIGNAQNDANLDAMGVKNITNIGGVI- 3141
+I A N S+G + + W TT L G + G K ++G +
Sbjct 2453 SIFAGINGSEGREKGNGTTWTETTLDAGKNVSLTSGRDTTLSGAQVSGEKVTADVGNNLT 2512
Query 3142 -----------ANANKNADGSLTDHKNLNYTGNLELKDLQDHNNNNS-----------SG 3179
+ N+ A G +++ +G + + +N +S G
Sbjct 2513 ISSLQDSDRYDSRQNRVAAGGSFTFGSMSGSGYASISQDKIKSNYDSVREQSGIYAGKDG 2572
Query 3180 FNVSTNIGIPQGGSKAASTAPKGSTTIGLNSSG 3212
F+V+ G+ ASTA ++ N+ G
Sbjct 2573 FDVTVGNHTQLNGAVIASTATDDKNSLNTNTLG 2605
Score = 55.8 bits (133), Expect = 2e-09
Identities = 213/1042 (20%), Positives = 375/1042 (36%), Gaps = 121/1042 (12%)
Query 2252 TADNVQNLNGRIQGNQVAIETQKDLNNIGGQIIAKDAMALKVGGNLNIESTTRTSESKVG 2311
T V N +G +Q +V E +N G DA+++ + + + + V
Sbjct 160 TGKPVMNADGSLQALEVT-EGSITINGAGLDGTRSDAVSI-IARATEVNAALHAKDLTVT 217
Query 2312 NFSSSITNVDRVAGLYVGNGSTKQLDPNQATL------MLNVAGNSSLKGVQINN---SN 2362
++ IT RV+ L G G+ ++ + L +++ S GV + N
Sbjct 218 AGANRITADGRVSALK-GEGNVPKVAVDTGALGGMYARRIHLTSTESGVGVNLGNLYARE 276
Query 2363 SATVLNTTGNVDLGTVSVGKQETLKIDDKNGYQLKQQQDVGSQIKSAGSLLINGQNITSK 2422
+L+++G + L G T+ D + + K+ G+L + G +
Sbjct 277 GDIILSSSGKLVLKNSLAGGNTTVTGTDVS---------LSGDNKAGGNLSVTG----TT 323
Query 2423 AVDLNSQQGDIQLSAQKDIVLDNGLNQSTVSSQSQSKGSFGGKKSSTYDASSSTSIANQL 2482
+ LN Q +V D L S+ Q+ G +++ A + +
Sbjct 324 GLTLN----------QSRLVTDKNLVLSSSGQIVQNGGELTAGQNAMLSAQHLNQTSGTV 373
Query 2483 NAGQNIIINSAQGNISATHLQAEAGNNIQIHAQQGNVTLLSAIDDKRESSTSSKKGVATY 2542
NA +N+ + + A + + TL++ D ++ T S G
Sbjct 374 NAAENVTLTTTDDTTLKGRSVAGKTLTVSSGSLNNGGTLVAGRDATVKTGTFSNTGTVQG 433
Query 2543 NNRQSGYIDQEVAQTTLKAGDTVDINAAKNIELQANDVQAGNS--IYVGNTLMQRQADGS 2600
N + D + ++K+G T+DI +A+N L + D A + + V TL R
Sbjct 434 NGLKVTATDL-TSTGSIKSGSTLDI-SARNATL-SGDAGAKDRALVTVSGTLENR----- 485
Query 2601 LKAADGSLMPENVTLSTLATKDEQWDEQQKGYRGIVKDIVKATAVGLAGIEALAPGLKAP 2660
G L+ ++V L+ AT+ G K++V A+A L E
Sbjct 486 -----GRLVSDDV-LTLSATQ-----INNSGTLSGAKELV-ASADTLTTTEKSVTNSDGN 533
Query 2661 KITVSESTGKRTEQISQTGSSLKADNVYVGSSGQTTLTSTDITAKNTILLGQK-----VT 2715
+ S S+ E + S+K +++ ++ QT S + +N L G + +T
Sbjct 534 LMLDSASSTLAGETSAGGTVSVKGNSLKTTTTAQTQGNSVSVDVQNAQLDGTQAARDILT 593
Query 2716 LNAAEEQKITVESTSKETVQGLGAKLNKDSIRLGGFVLEDASQSSKTTETTHKLGS--IN 2773
LNA+E K+T S L A S L G L SQ+ + S +N
Sbjct 594 LNASE--KLTHSGKSSAPSLSLSAPELTSSGVLVGSALNTQSQTLTNSGLLQGKASLTVN 651
Query 2774 TENLKIQGVEGVDILGQNITATGDTLIDHGRGDLNVGGYENKTTVEDKTHVETISTEVGV 2833
T+ L Q G ++T + + G + G N ++ + + I+ + V
Sbjct 652 TQRLDNQ-QNGTLYSAADLTLDIPDIRNSGLITGDNGLMLNAVSLSNPGKI--IADTLSV 708
Query 2834 RNAYLDAALAL---GAVKDAAEAVKQAKDQYSQAQRDYA-SGKITKEALDDSKANVAMAT 2889
R LD L GA+ A + + + D + GK A N+ +
Sbjct 709 RATTLDGDGLLQGAGALALAGDTLSLGSNGRWLTAGDLSLRGKTLHTAGTTQGQNLTVQA 768
Query 2890 ANLANAQIAVGSAAATAAASSATYGFTIGANGERIETTNTTNTTQGKWQGSTLELNNLTL 2949
AN+ GS AT +++ G + T N +GS L L+L
Sbjct 769 DRWANS----GSVQATGNLTASATGQLTSTGDIMSQGDTTLNAATTDNRGSLLSAGTLSL 824
Query 2950 KSENQDVN--VQGSRLT-----ATGTTSFDGTKDLNVTAGTEHSQQETSSKTNSQSVSYT 3002
+ D + VQG+ +T T + + G L + A + + + + N
Sbjct 825 DGNSLDNSGTVQGNHVTIRQNGVTNSGTLTGIAALTLAARMDMASPQPALMNN------- 877
Query 3003 YGGGGSASIGKQTSTSESKSLTYVNSEVTLNKTEGRLNSLNIKGGEVSIQDRGNLQVNNI 3062
GG + G T T + SL + + RL + + G + ++ +
Sbjct 878 --GGSLLTSGDLTIT--AGSLANSGAIQAADSLTARLTGELVSTAGSKVTSNGEMALSAL 933
Query 3063 HVESLQDTASSSNSSRGGSI-GGGYGSGSKNITASYNQSKGSSDSAWVNTTSKLLIGNAQ 3121
++ + + + + + S+ G +G +T + NQ+ + + + KLL
Sbjct 934 NLSNSGQWIAKNLTLKANSLTSAGDITGVDALTLTVNQTLNN------HASGKLL----- 982
Query 3122 NDANLDAMGVKNITNIGGVIANANKNADGSLTDHKNLNYTGNLELKDLQDHNNNNSSG-- 3179
A + + ++ N G + NA G LT+ +L G NN S G
Sbjct 983 -SAGVLTLKADSVKNDGQLQGNATTITAGQLTNGGHLQ--GETLTLAASGGVNNRSGGVL 1039
Query 3180 -----FNVST----NIGIPQGGSKAASTAPKGSTTIGLNSSGQETEQLTKATLGQGSVTN 3230
NVST N G QGG + A G SG + GS
Sbjct 1040 MSRNALNVSTATLSNQGTIQGGGGVSLNATDRLQNDGKILSGSNLTLTAQVLANTGSGLV 1099
Query 3231 ATADTNRDINNTQEITRDQTTG 3252
A D+ NT R TG
Sbjct 1100 QAATLLLDVVNTVNGGRVLATG 1121
Score = 51.6 bits (122), Expect = 3e-08
Identities = 131/621 (21%), Positives = 237/621 (38%), Gaps = 104/621 (17%)
Query 2662 ITVSESTGKRTEQISQTGSSLKAD-NVYVGSSGQTTLTSTDITA-KNTILLGQKV----- 2714
++V+ +TG Q S L D N+ + SSGQ ++TA +N +L Q +
Sbjct 317 LSVTGTTGLTLNQ-----SRLVTDKNLVLSSSGQIVQNGGELTAGQNAMLSAQHLNQTSG 371
Query 2715 TLNAAEEQKITV--ESTSK-ETVQGLGAKLNKDSIRLGGFVLEDASQSSKTTETTHKLGS 2771
T+NAAE +T ++T K +V G ++ S+ GG ++ + KT T G+
Sbjct 372 TVNAAENVTLTTTDDTTLKGRSVAGKTLTVSSGSLNNGGTLVAGRDATVKTG-TFSNTGT 430
Query 2772 INTENLKIQGVEGVDILGQNITATGDTLIDHGRGDLNVGGYENKTTVEDKTHVETISTEV 2831
+ LK+ TAT T + G ++ +T++ T+S +
Sbjct 431 VQGNGLKV-------------TATDLT---------STGSIKSGSTLDISARNATLSGDA 468
Query 2832 GVRNAYLDAALALGAVKDAAEAVKQAKDQYSQAQRDYA---SGKITKEALDDSKANVAMA 2888
G ++ L G +++ V S Q + + SG A D+ +
Sbjct 469 GAKDRAL--VTVSGTLENRGRLVSDDVLTLSATQINNSGTLSGAKELVASADTLTTTEKS 526
Query 2889 TANLANAQIAVGSAAATAAASSATYGFTIGANGERIETTNTTNTTQGKWQGSTLELNNLT 2948
N ++ + + SA++T A ++ G T+ G ++TT T T QG+++
Sbjct 527 VTN-SDGNLMLDSASSTLAGETSAGG-TVSVKGNSLKTTTTAQT-----QGNSVS----- 574
Query 2949 LKSENQDVNVQGSRLTATGTTSFDGTKDLNVTAGTEHSQQETSSKTNSQSVSYTYGGGGS 3008
V+VQ ++L GT + LN + HS + ++ + + T G
Sbjct 575 -------VDVQNAQLD--GTQAARDILTLNASEKLTHSGKSSAPSLSLSAPELTSSG--- 622
Query 3009 ASIGKQTSTSESKSLTYVNSEVTLNKTEGRLNSLNIKGGEVSIQDRGNLQVNNIHVESLQ 3068
+G +T +S T NS + K SL + + Q G L S
Sbjct 623 VLVGSALNT---QSQTLTNSGLLQGKA-----SLTVNTQRLDNQQNGTLY-------SAA 667
Query 3069 DTASSSNSSRGGSIGGGYGSGSKNITASYNQSKGSSDSAWVNTTSKLLIGNAQNDANLDA 3128
D R + G N + N K +D+ V T+ LD
Sbjct 668 DLTLDIPDIRNSGLITGDNGLMLNAVSLSNPGKIIADTLSVRATT------------LDG 715
Query 3129 MGVKNITNIGGVIANANKNADGSLTDHKNLNYTGNLELKDLQDHNNNNSSGFNVSTNIGI 3188
G+ + G A A SL + G+L L+ H + G N++
Sbjct 716 DGL-----LQGAGALALAGDTLSLGSNGRWLTAGDLSLRGKTLHTAGTTQGQNLTV---- 766
Query 3189 PQGGSKAASTAPKGSTTIGLNSSGQETEQLTKATLGQGSVTNATADTNRDINNTQEITRD 3248
Q A S + + + + +++GQ T + G ++ AT D + + ++ D
Sbjct 767 -QADRWANSGSVQATGNLTASATGQLTSTGDIMSQGDTTLNAATTDNRGSLLSAGTLSLD 825
Query 3249 QTTGMLNGSVTVDHRLLSESG 3269
+ +G+V +H + ++G
Sbjct 826 GNSLDNSGTVQGNHVTIRQNG 846
Score = 50.8 bits (120), Expect = 5e-08
Identities = 171/860 (20%), Positives = 304/860 (35%), Gaps = 115/860 (13%)
Query 2668 TGKRTEQISQTG--SSLKADNVYVGSSGQTTLTSTDITAKNTILLGQKVTLNAAEEQKIT 2725
+GK S TG S+L + ++G + TD + + + AA + IT
Sbjct 1887 SGKTVSLESATGNISNLTRTEQWAMNNGYNHFSGTDTGPLAAVRATDSLFMGAAGDISIT 1946
Query 2726 --VESTSKETVQGLGAKLNKDSIRLGGFVLEDASQSSKTTETTHKLGSINTENLKIQGVE 2783
S + G LN ++I+ G E TH + T +
Sbjct 1947 GAAVSAGDSVLLAAGNDLNMNAIQAG----ERRRYGGSGWYETHAVAPTVTAGNSLMLSA 2002
Query 2784 GVDILGQNITATGDTLIDHGRG-DLNVGGYENKTTVEDKTHVETISTEVGVRNAYLDAAL 2842
G D+ Q T + +D G D+N+ AA
Sbjct 2003 GRDVNSQAAGITAENSMDIRAGRDVNM------------------------------AAE 2032
Query 2843 ALGAVK-DAAEAVKQAKDQYSQAQRDYASGKITKEALDDSKANVAMATANLANAQIAVGS 2901
+ GA D+ ++K D Q D SG +VA A + ++ G
Sbjct 2033 STGAGDHDSTFSMKTVHDSVRQQGTDMTSGGDITVTAGRDITSVATAVTAKGDIRVNAGH 2092
Query 2902 AAATAAASSATYGFT-IGANGERIETTNTTNT----TQGKWQGSTLELNNLTLKSENQDV 2956
A+ + Y ++ G R+ + TT T + + +GS L N +T+ + N ++
Sbjct 2093 DIVLGTATESDYHYSESGETRNRLLSHQTTRTITEDSVTREKGSLLSGNRVTVNAGN-NL 2151
Query 2957 NVQGSRLTATGTTSFDGTKDLNVTAGTE------HSQQETSSKTNSQSVSYTYGGGGSAS 3010
VQGS + A S ++V A T + +TS T + + +T G +
Sbjct 2152 TVQGSDVVADRDVSLAADNHVDVLAATSTDTSWRFKETKTSGLTGTGGIGFTTGSSKTTH 2211
Query 3011 IGKQTSTSESKSLTYVNSEV-TLNKTEGRLNSLNIKGGEVSIQDRGNLQVNNIHVE---- 3065
++ T++S+S + + S ++ T G+ +I G +V ++ +++ V+
Sbjct 2212 DRREAGTTQSQSASTIGSTAGNVSITAGK--QAHISGSDVIANRDISITGDSVVVDPGHD 2269
Query 3066 --SLQDTASSSNSSRGGSIGGGYGSGSKNITASYNQSKGSSDS--AWVNTTSKLLIGNAQ 3121
++ + S ++ G GS N ++K +SDS A + T +L G Q
Sbjct 2270 RRTVDEKFEQKKSGLTVALSGAVGSAINNAVTMAREAKETSDSRLAALKGTQAVLSG-VQ 2328
Query 3122 NDANLDAMGVKNITNIG-GVIANANKNADGSLTDHKN-------LNYTGNLELKDLQDHN 3173
N N G GV + N S T +++ L+ N+ + +
Sbjct 2329 AGVNHGLQQQSADPNNGIGVSISLNHQQSKSETKYQHDIVSGSTLSAGNNVSVTATGKNK 2388
Query 3174 NNNSSGFNVSTNIGIPQGGSKAASTAPKGSTTIGLNSSGQETEQLT--KATLGQGSVTNA 3231
++N+SG + T I G T+ I L ++ +T Q T ++ G G +
Sbjct 2389 DHNNSGDMLITGSQIKSGND----TSLNAQNDI-LLAAAADTRQTTGKNSSKGGGVGVSF 2443
Query 3232 TADTN-------RDINNTQEITRDQTTGMLNGSVTVDHRLLSESGRAEIVKEQEQLIENF 3284
TN IN ++ + T ++ + SGR +
Sbjct 2444 GGGTNGGGLSIFAGINGSEGREKGNGTTWTETTLDAGKNVSLTSGR-----------DTT 2492
Query 3285 RQSAENLAKALPDGVYKDKALQTLNDVQAKLYNLPSEYKEVGVVGNSVASELLKRGMESQ 3344
A+ + + V + + +L D S V G+ + G S
Sbjct 2493 LSGAQVSGEKVTADVGNNLTISSLQDSD----RYDSRQNRVAAGGSFTFGSMSGSGYASI 2548
Query 3345 DVEALFSKLDFFYAAKEFSEIQNQLTDLEKSGVNLETIFKQPKAGVNEQETIYAQGTDFE 3404
+ + S D + +E S I K G ++ G I + TD +
Sbjct 2549 SQDKIKSNYD---SVREQSGIY-----AGKDGFDVTVGNHTQLNGA----VIASTATDDK 2596
Query 3405 TKVRSQTTLGMTILSNIADLGNSIKDISESTGVDIEKVQLAVGLLISGPVR-LVIESGKS 3463
+ + T LG + + N AD S IS S G + Q+ I+G L SG S
Sbjct 2597 NSLNTNT-LGWSDIHNQADYKASHTGISLSGGSGMSASQMVASNAIAGAANALTGMSGSS 2655
Query 3464 MAVDSVVGEKVAQGVDILAN 3483
+ ++ G I+ N
Sbjct 2656 GHAEGTTSSAISGGNLIIRN 2675
Score = 49.3 bits (116), Expect = 2e-07
Identities = 243/1196 (20%), Positives = 436/1196 (36%), Gaps = 210/1196 (18%)
Query 330 GVGVRNAGSMNSTQSTLTLNANGDLTNTGNLIANQGQLQLNAENIKNTGNISSATS--QV 387
G + N+GS + Q+ L L+ G + N + N G LN + I + GNISS S V
Sbjct 1833 GGNITNSGSSINAQNDLLLDRTGSIDNLNAGLINAGG-ALNLKAIGDIGNISSVISGKTV 1891
Query 388 SLHSQNLDNSGL-------------------------ISSADELNIQQQGHVGNRGTLNA 422
SL S + S L + + D L + G + G +
Sbjct 1892 SLESATGNISNLTRTEQWAMNNGYNHFSGTDTGPLAAVRATDSLFMGAAGDISITGAAVS 1951
Query 423 A--RIVVDAGSLANSGSIE-------------QTGAQALDLKAGS--MSNIGGKIGIAKT 465
A +++ AG+ N +I+ +T A A + AG+ M + G +
Sbjct 1952 AGDSVLLAAGNDLNMNAIQAGERRRYGGSGWYETHAVAPTVTAGNSLMLSAGRDVNSQAA 2011
Query 466 SSTGGNGSESGGGSQPVEPNNAAQDGGSLEVVNTDSTPTTPKTYETGYIHVRDQLNN--D 523
T N + G + N AA+ G+ + +T S T + VR Q +
Sbjct 2012 GITAENSMDIRAGR---DVNMAAESTGAGDHDSTFSMKTV-------HDSVRQQGTDMTS 2061
Query 524 QGAIVAQGGIDLESNNGLDNQGG--QLNLGRVKIQGERFNNDQGQLTVKQAEIQTNSLSN 581
G I G D+ S G ++N G + G +D + E + LS+
Sbjct 2062 GGDITVTAGRDITSVATAVTAKGDIRVNAGHDIVLGTATESDYHY--SESGETRNRLLSH 2119
Query 582 QSGQLISNQKLNIQTQTANNQKGKIQSVDQLDLNVANGLNNIEGQIASGQQLNIQADQVN 641
Q+ + I+ + +KG + S +++ +N N L + + + +++ AD
Sbjct 2120 QTTRTITE-------DSVTREKGSLLSGNRVTVNAGNNLTVQGSDVVADRDVSLAAD--- 2169
Query 642 NQSGLIYSEQQGIELKANHAINNTSGIIQAKTQLNLASTQLDNTSGHIQAENIQQQHTTV 701
+++ A + + + + KT + + T+G + + +++ T
Sbjct 2170 ----------NHVDVLAATSTDTSWRFKETKTSGLTGTGGIGFTTGSSKTTHDRREAGTT 2219
Query 702 NNTQGSIVAGQSLISTVDQFDNHQGLIDAKNIQLT--HQVLNNSGSIYADQNIKITGQHI 759
+ S + A N+ +T Q + + A+++I ITG +
Sbjct 2220 QSQSASTIGS-----------------TAGNVSITAGKQAHISGSDVIANRDISITGDSV 2262
Query 760 LNTGSIAAGQNIQLNTAKLQHEQAALIAAGLDRQGKLTSTGDLDITAEQTTLHGQ--SFA 817
+ + G + + K + +++ L A G + + T + +
Sbjct 2263 V----VDPGHDRRTVDEKFEQKKSGLTVALSGAVGSAINNAVTMAREAKETSDSRLAALK 2318
Query 818 GQQLKVASKQQIDATNGQLQAKNIDLASDAGDISTRAATVIAEQLSLKSHDLIDNQQGTL 877
G Q ++ Q N LQ ++ D + G +S ++ + HD++ TL
Sbjct 2319 GTQAVLSGVQA--GVNHGLQQQSADPNNGIG-VSISLNHQQSKSETKYQHDIVSG--STL 2373
Query 878 SA-QQLNLTA---NRLDNTQGHILHTGQDQLDLNFSQSLNNQLGEIRSNAAELNIKTALL 933
SA +++TA N+ N G +L TG Q+ SLN Q + + AA+ T
Sbjct 2374 SAGNNVSVTATGKNKDHNNSGDMLITG-SQIKSGNDTSLNAQNDILLAAAADTRQTTGKN 2432
Query 934 NNTEGQV---VHAGTQQLNIQT-AQLNGHLGHILSNGTLQLKAGTLDVSGGV--TSADQI 987
++ G V GT + A +NG G NGT + TLD V TS
Sbjct 2433 SSKGGGVGVSFGGGTNGGGLSIFAGINGSEGREKGNGTTWTET-TLDAGKNVSLTSGRDT 2491
Query 988 TIQANVLNNAQGQLIQRGTSNPLNL-TIQQQLNNQAGLIQSATATDIKAGSLNNQRGTLS 1046
T+ G+ + N L + ++Q + + A GS++ G S
Sbjct 2492 TLSG---AQVSGEKVTADVGNNLTISSLQDSDRYDSRQNRVAAGGSFTFGSMSGS-GYAS 2547
Query 1047 SAQGQNLDVDVAGKLDN--SQSGQIYAGNQA-------HLQV-GSIDNSHQGQINAQQNL 1096
+Q + + D+ QSG IYAG H Q+ G++ S N
Sbjct 2548 ISQDK-----IKSNYDSVREQSG-IYAGKDGFDVTVGNHTQLNGAVIASTATDDKNSLNT 2601
Query 1097 QLTSQQQINNQ-------------------SGQIVANGDVQIQSQGLNNSHGQMGSLQGG 1137
I+NQ + Q+VA+ + + L G G +G
Sbjct 2602 NTLGWSDIHNQADYKASHTGISLSGGSGMSASQMVASNAIAGAANALTGMSGSSGHAEGT 2661
Query 1138 LSLNTGSDTLINQSGLIQAKKDIGIQAQRIDNQQGQIT----------TQGQAELISQ-- 1185
S LI ++ Q K+DI ++ +N G I +A++ISQ
Sbjct 2662 TSSAISGGNLIIRNKESQ-KQDIAGLSRDPENANGSIAPIFDREKEQKRLQEAQVISQIS 2720
Query 1186 AEIDNL---EGAIAADLDVNIRSQGLNNNKGQISSAQGNLTLNAGNGTLTNQAATIVSGK 1242
++ N+ G A G+++ + + + + G G+ ++G
Sbjct 2721 GQMSNIVMTYGETEAMKAARKEHPGMSDAQLRETPEYREVMKGYGTGSTPQMVVQAITGV 2780
Query 1243 TLTLSANQLDNSNHGQI--NSQNNADISIVKDI---NNTSGVIAAKQQLILSSQ--GLNN 1295
L+A N GQ+ N A ++K N + ++A L++Q G N
Sbjct 2781 LGGLNA-----GNPGQVLAGGLNPAVAQLIKQATGDNREANLMAHAVWGALAAQLGGNNA 2835
Query 1296 TTGQIGTVQGNLHIDAGSQLLNNQQG------RIQSGQDLNLNATGIDNTQGQISSKNQL 1349
+G G G L A +++N G Q Q +++ AT G + +
Sbjct 2836 ASGAAGAFSGEL---AARYIIDNYYGGRTDNLSEQERQQISMLATIASGIAGGLVGNSTS 2892
Query 1350 QLDSREQLLNNRQGTLSAENLTID--SGELNNDQGLIQAQQSIQIDTHQHNLSNTN 1403
+ Q G S EN + G Q +QAQ+++ +T NL++ N
Sbjct 2893 AAGTGAQ-----AGRNSVENNAMSGLEGFGTGFQSYVQAQEALVNNT---NLTDKN 2940
Score = 44.3 bits (103), Expect = 5e-06
Identities = 186/997 (19%), Positives = 369/997 (37%), Gaps = 125/997 (13%)
Query 333 VRNAGSMNSTQSTLTLNANGDLTNTGNLIANQGQLQLNA--ENIKNTGNISSATSQVSLH 390
VR G+ ++ +T+ A D+T+ + +G +++NA + + T S S
Sbjct 2052 VRQQGTDMTSGGDITVTAGRDITSVATAVTAKGDIRVNAGHDIVLGTATESDYHYSESGE 2111
Query 391 SQN--LDNSGLISSADELNIQQQGHV--GNRGTLNAA-RIVVDAGSLANSGSIEQTGAQA 445
++N L + + ++ +++G + GNR T+NA + V + +
Sbjct 2112 TRNRLLSHQTTRTITEDSVTREKGSLLSGNRVTVNAGNNLTVQGSDVVADRDVSLAADNH 2171
Query 446 LDLKAGSMSNIGGKIGIAKTS---STGGNGSESGGGSQPVEPNNAAQDGGSLEVVNTDST 502
+D+ A + ++ + KTS TGG G +G + D + S
Sbjct 2172 VDVLAATSTDTSWRFKETKTSGLTGTGGIGFTTGS-------SKTTHDRREAGTTQSQSA 2224
Query 503 PTTPKTYETGYIHVRDQLNNDQGAIVAQGGIDLESNNGLDNQGGQLNLGRVKIQGERFNN 562
T T I Q + ++A I + ++ + + G + E+F
Sbjct 2225 STIGSTAGNVSITAGKQAHISGSDVIANRDISITGDSVVVDPGHDR-----RTVDEKFEQ 2279
Query 563 DQGQLTVKQAEIQTNSLSNQSGQLISNQKLNIQ--TQTANNQKGKIQSVDQLDLNVANGL 620
+ LTV +LS G I+N + +T++++ ++ + V G+
Sbjct 2280 KKSGLTV--------ALSGAVGSAINNAVTMAREAKETSDSRLAALKGTQAVLSGVQAGV 2331
Query 621 NN-IEGQIAS-----GQQLNIQADQVNNQSGLIYSEQQGIELKANHAI-----------N 663
N+ ++ Q A G +++ Q +++ + G L A + + N
Sbjct 2332 NHGLQQQSADPNNGIGVSISLNHQQSKSETKYQHDIVSGSTLSAGNNVSVTATGKNKDHN 2391
Query 664 NTSGIIQAKTQLNLAS-TQLDNTSGHIQAENIQQQHTTVNNTQGSIVAGQSL-------- 714
N+ ++ +Q+ + T L+ + + A + TT N+ G S
Sbjct 2392 NSGDMLITGSQIKSGNDTSLNAQNDILLAAAADTRQTTGKNSSKGGGVGVSFGGGTNGGG 2451
Query 715 ISTVDQFDNHQGLIDAKNIQLTHQVLNNSGSIYADQNIKIT-GQHILNTGSIAAGQNI-- 771
+S + +G T L+ A +N+ +T G+ +G+ +G+ +
Sbjct 2452 LSIFAGINGSEGREKGNGTTWTETTLD------AGKNVSLTSGRDTTLSGAQVSGEKVTA 2505
Query 772 ----QLNTAKLQ------HEQAALIAAGLDRQGKLTSTGDLDITAEQTTLHGQSFAGQQL 821
L + LQ Q + A G G ++ +G I+ ++ + S Q
Sbjct 2506 DVGNNLTISSLQDSDRYDSRQNRVAAGGSFTFGSMSGSGYASISQDKIKSNYDSVREQSG 2565
Query 822 KVASKQQIDATNG-QLQAKNIDLASDAGD------ISTRAATVIAEQLSLK-SHDLIDNQ 873
A K D T G Q +AS A D +T + I Q K SH I
Sbjct 2566 IYAGKDGFDVTVGNHTQLNGAVIASTATDDKNSLNTNTLGWSDIHNQADYKASHTGISLS 2625
Query 874 QGT-LSAQQLNLT------ANRLDNTQGHILHT-GQDQLDLNFSQSLNNQLGEIRSNAAE 925
G+ +SA Q+ + AN L G H G ++ + + + A
Sbjct 2626 GGSGMSASQMVASNAIAGAANALTGMSGSSGHAEGTTSSAISGGNLIIRNKESQKQDIAG 2685
Query 926 LNIKTALLNNTEGQVVHAGTQQLNIQTAQLNGHLGHILSNGTLQLKAGTLDVSGGVTSAD 985
L+ N + + +Q +Q AQ+ + +SN + + G +
Sbjct 2686 LSRDPENANGSIAPIFDREKEQKRLQEAQVISQISGQMSN--IVMTYGETEAMKAARKEH 2743
Query 986 QITIQANVLNNAQGQLIQR--GTSNPLNLTIQQQLNNQAGLIQSATATDIKAGSLNNQRG 1043
A + + + + + GT + + + Q + G + + + AG LN
Sbjct 2744 PGMSDAQLRETPEYREVMKGYGTGSTPQMVV-QAITGVLGGLNAGNPGQVLAGGLNPAVA 2802
Query 1044 TL-SSAQGQNLDVD-VAGKLDNSQSGQIYAGNQAHLQVGS----------IDNSHQGQIN 1091
L A G N + + +A + + + Q+ N A G+ IDN + G+ +
Sbjct 2803 QLIKQATGDNREANLMAHAVWGALAAQLGGNNAASGAAGAFSGELAARYIIDNYYGGRTD 2862
Query 1092 AQQNLQLTSQQQINNQSGQIVANGDVQIQSQGLNNSHGQMGSLQGGLSLNTGSDTLINQS 1151
NL +QQI+ + +A+G + G + S G+ G S+ + + +
Sbjct 2863 ---NLSEQERQQISMLA--TIASG-IAGGLVGNSTSAAGTGAQAGRNSVENNAMSGLEGF 2916
Query 1152 G-----LIQAKKDIGIQAQRIDNQQGQITTQGQAELISQAEIDNLEGAIAADLDVNIRSQ 1206
G +QA++ + + + ++ G++ E I A + G+I D ++
Sbjct 2917 GTGFQSYVQAQEAL-VNNTNLTDKNGKVLNPATPEEIKYASDKLVTGSIPEGQD---PAR 2972
Query 1207 GLNNNKGQISSAQGNLTLNAGNGTLTNQAATIVSGKT 1243
GL + G +S G + GT+ T++ G T
Sbjct 2973 GLLISWGAGASVFGGELIAPAVGTVAVIGGTLLGGTT 3009
Score = 43.5 bits (101), Expect = 9e-06
Identities = 272/1374 (20%), Positives = 477/1374 (35%), Gaps = 247/1374 (18%)
Query 1878 GQIKAGGHLDLNGAQVVNDKSQILAGGELKNEGGTIDSG-TQIAGIRKIVNTGTQVKYWK 1936
G + A ++ L K + +AG L G++++G T +AG V TGT
Sbjct 371 GTVNAAENVTLTTTDDTTLKGRSVAGKTLTVSSGSLNNGGTLVAGRDATVKTGTFSNTGT 430
Query 1937 YEGQW--------DNPFENSSETTFDLSISQALGNQNLNQNQLSTVAVSNNQ-------- 1980
+G + S +T D+S A + + + V VS
Sbjct 431 VQGNGLKVTATDLTSTGSIKSGSTLDISARNATLSGDAGAKDRALVTVSGTLENRGRLVS 490
Query 1981 ------SAEHIQNSQTTQQEINGLQTSNNNTQLNQTKDVDLDQLNLKDSQSQNAPQASAV 2034
SA I NS T + +++ T ++ L L + S A + SA
Sbjct 491 DDVLTLSATQINNSGTLSGAKELVASADTLTTTEKSVTNSDGNLMLDSASSTLAGETSAG 550
Query 2035 ETVQQQSATSAPSSTPQGTSEEIRSIDFSNIKVPNSA----LYKVNADSKAGYLIETD-P 2089
TV + + ++T Q + S+D N ++ + + +NA K + ++ P
Sbjct 551 GTVSVKGNSLKTTTTAQTQGNSV-SVDVQNAQLDGTQAARDILTLNASEKLTHSGKSSAP 609
Query 2090 AFADYKKWLSSDYMLDALGLDPALQQKRLGDGFYEQRLVQDQIANLTGYRFLEGFANDDE 2149
+ + L+S +L L+ Q LT L+G A+
Sbjct 610 SLSLSAPELTSSGVLVGSALNTQSQ-------------------TLTNSGLLQGKASLTV 650
Query 2150 QYKALMN--NGITFAKLYGLRPGIALTAAQTAQLTSDIVWLVEQS-VTLPDGTITKAL-- 2204
+ L N NG ++ A LT DI + +T +G + A+
Sbjct 651 NTQRLDNQQNGTLYS---------------AADLTLDIPDIRNSGLITGDNGLMLNAVSL 695
Query 2205 -----VPQVYVKVRVGDLKGDGTL-------LSGNSVNLKLDGDLINGATIAGREALQIT 2252
+ + VR L GDG L L+G++++L +G + ++ R T
Sbjct 696 SNPGKIIADTLSVRATTLDGDGLLQGAGALALAGDTLSLGSNGRWLTAGDLSLRGKTLHT 755
Query 2253 ADNVQNLNGRIQG----NQVAIETQKDLN-NIGGQIIAKDAMALKVGGNLNIEST-TRTS 2306
A Q N +Q N +++ +L + GQ+ + + + LN +T R S
Sbjct 756 AGTTQGQNLTVQADRWANSGSVQATGNLTASATGQLTSTGDIMSQGDTTLNAATTDNRGS 815
Query 2307 ESKVGNFSSSITNVDRVAGLYVGNGSTKQLD--PNQATLM----LNVAGNSSLKGVQINN 2360
G S ++D +G GN T + + N TL L +A + Q
Sbjct 816 LLSAGTLSLDGNSLDN-SGTVQGNHVTIRQNGVTNSGTLTGIAALTLAARMDMASPQPAL 874
Query 2361 SNSATVLNTTGNVDLGTVSVGKQETLKIDDKNGYQLKQQ--QDVGSQIKSAGSLLING-- 2416
N+ L T+G++ + S+ ++ D +L + GS++ S G + ++
Sbjct 875 MNNGGSLLTSGDLTITAGSLANSGAIQAADSLTARLTGELVSTAGSKVTSNGEMALSALN 934
Query 2417 ---------QNITSKAVDLNSQQGDIQLSAQKDIVLDNGLNQSTVSSQSQSKGSFGGKKS 2467
+N+T KA L S GDI + ++ LN S + S G K
Sbjct 935 LSNSGQWIAKNLTLKANSLTSA-GDITGVDALTLTVNQTLNNHA-SGKLLSAGVLTLKAD 992
Query 2468 STYDASSSTSIANQLNAGQNIIINSAQGNISATHLQAEAGNNIQIHAQQGNVTLLSAIDD 2527
S + A + AGQ + N L A G ++ + G V +
Sbjct 993 SVKNDGQLQGNATTITAGQ--LTNGGHLQGETLTLAASGG----VNNRSGGVLM------ 1040
Query 2528 KRESSTSSKKGVATYNNRQSGYIDQEVAQTTLKAGDTVDINAAKNIELQANDVQAGNSIY 2587
S + AT +N Q T++ G V +NA ++ + N
Sbjct 1041 ---SRNALNVSTATLSN-----------QGTIQGGGGVSLNATDRLQNDGKILSGSNLTL 1086
Query 2588 V-------GNTLMQ---------RQADGSLKAADGSLMPENVTLSTLATKDEQWDEQQKG 2631
G+ L+Q +G A GS + TL+ T Q +
Sbjct 1087 TAQVLANTGSGLVQAATLLLDVVNTVNGGRVLATGSADVKGTTLNNTGTF--QGADLLVN 1144
Query 2632 YRGIVKDIVKATAVGLAGIEALAPGLKAPKITVSESTGKRTEQISQTGSSLKADNVYVGS 2691
Y T +G +G+ G+K + + TG+ + +L D
Sbjct 1145 YHTFSNS---GTLLGTSGL-----GVKGSSL-LQNGTGRL-----YSAGNLLLDAQDFSG 1190
Query 2692 SGQTTLTSTDITAKNTILLGQKVTLNAAEEQKITVESTSKETVQGLGAKLNKDSIRLGGF 2751
GQ T D+T K L TL A + T+ TS+ V G + D++ LG
Sbjct 1191 QGQVVATG-DVTLKLIAALTNHGTLAAGK----TLSVTSQNAVTN-GGVMQGDAMVLGA- 1243
Query 2752 VLEDASQSSKTTETTHKLGSINTENLKIQGVEGVDILGQNITATGDTLIDHGRGDLNVGG 2811
+ ++ T T K S+ + G ++ A GD ++ R D+ + G
Sbjct 1244 ---GEAFTNNGTLTAGKGNSVFSAQRLFLNAPG------SLQAGGDVSLN-SRSDITISG 1293
Query 2812 YENKTTVEDKTHVETISTEVGVRNAYLDAALALGAVKDAAEAVKQAKDQYSQAQRDYASG 2871
+ S + V L++AL A +K D+ D +G
Sbjct 1294 FTGTAG----------SLTMNVAGTLLNSALIY-----AGNNLKLFTDRLHNQHGDILAG 1338
Query 2872 K---ITKEA--------------LDDSKANVAMATANLANAQIAVGSAAATAAASSATYG 2914
+ K++ ++ ++ ++ M TA+L N+ A+ ++ SS
Sbjct 1339 NSLWVQKDSSGTANSEIINRSGNIETTRGDITMNTAHLLNSWDAISASHEVIPGSSHGVI 1398
Query 2915 FTIGANGE-----RIETTNTTNTTQGKWQGSTLELNNLTLKSENQDVNVQGSRLTATGTT 2969
+ N R + GK G+T+ + + V V S A
Sbjct 1399 SPVPENNRWWGVVRHDGVEYLAVYWGK--GATVPDEYRIRTGDTETVTVSASGHAAR--- 1453
Query 2970 SFDGTKDLNVTAGTEHSQQE--------TSSKTNSQSVSYTYGGGGSASIGKQTSTSESK 3021
G D+++ AG ++ T S + + G G ++ + S S K
Sbjct 1454 -ISGGADMHIRAGRLDNEASFILAGGGMTLSGDTLNNQGWQEGTTGKETVWRLASGSLPK 1512
Query 3022 SLTY-----VNSEVTLNKTEGRLNSLNIKGGEVSIQDRGNLQV-NNIHVESLQDTASSSN 3075
+ V +V+ + TE G + Q R + ++ DT +++
Sbjct 1513 AWFTEPWYKVYRQVSPDATEA-------SGTSPAGQYRAVISAAGDVSASFATDTGNTTV 1565
Query 3076 SSRGGSIGGGYGSGSKNITASYNQSKGSSDSAWVNTTSKLLIGNAQNDANLDAM 3129
R G G S N S+G S A +N + + G NDA D +
Sbjct 1566 MPRAGGAGNTITVPSLNSLTPPTVSQGVSGEALLNESGTGITGPVWNDALPDTL 1619
Score = 38.1 bits (87), Expect = 4e-04
Identities = 126/564 (22%), Positives = 202/564 (36%), Gaps = 88/564 (16%)
Query 47 SDSDSMGFDSSHLKKLKQLN-FAVISVLGASIFTLPLNTIA-DSQIIADKGAPTSQQPTI 104
S D G D+ L + LN A +L A + TL +++ D Q+ + T+ Q T
Sbjct 955 SAGDITGVDALTLTVNQTLNNHASGKLLSAGVLTLKADSVKNDGQLQGNATTITAGQLTN 1014
Query 105 LNSSNGVTQVNIQTPSAGGVSRNTYSQFDVGQEGAIL--NNARNNTQTQLG--GWIQGNP 160
G T + ++GGV+ + G +L NA N + L G IQG
Sbjct 1015 GGHLQGET---LTLAASGGVNNRS---------GGVLMSRNALNVSTATLSNQGTIQGGG 1062
Query 161 WLAKGEAKVILNEVNSSNPSQLKGYIEVAGKQAQVVIANPSGLVCDGCGVINADRFTLT- 219
++ + N+ + S L +V ++ + L+ D +N R T
Sbjct 1063 GVSLNATDRLQNDGKILSGSNLTLTAQVLANTGSGLV-QAATLLLDVVNTVNGGRVLATG 1121
Query 220 ----TGQAVMNQGYLESFRVREGQITIQGKGLNGSLTPFTDVYARALQVNAGLYAKELNV 275
G + N G + + T G + + LQ G N+
Sbjct 1122 SADVKGTTLNNTGTFQGADLLVNYHTFSNSGTLLGTSGLGVKGSSLLQNGTGRLYSAGNL 1181
Query 276 VLGQNDIN-------VNDPTTSNVSPIQSN-TSANNKPQFALDVGQL--GGMYAGKIFLV 325
+L D + D T ++ + ++ T A K + GG+ G ++
Sbjct 1182 LLDAQDFSGQGQVVATGDVTLKLIAALTNHGTLAAGKTLSVTSQNAVTNGGVMQGDAMVL 1241
Query 326 GTEQGV---GVRNAGSMNSTQST--LTLNANGDLTNTGNLIANQGQLQLNAENIKNTGNI 380
G + G AG NS S L LNA G L G++ N + +I +G
Sbjct 1242 GAGEAFTNNGTLTAGKGNSVFSAQRLFLNAPGSLQAGGDVSLN------SRSDITISGFT 1295
Query 381 SSATSQVSLHSQNLDNSGLISSADELNIQQQGHVGNRGTL---NAARIVVDAGSLANS-- 435
+A S + L NS LI + + L + G + N+ + D+ ANS
Sbjct 1296 GTAGSLTMNVAGTLLNSALIYAGNNLKLFTDRLHNQHGDILAGNSLWVQKDSSGTANSEI 1355
Query 436 ----GSIEQTGAQALDLKAGSMSNIGGKIGIAKTSSTGGNGSESGGGSQPVEPNN----- 486
G+IE T + + + N I + G S G PV NN
Sbjct 1356 INRSGNIETTRGD-ITMNTAHLLNSWDAISASHEVIPGS----SHGVISPVPENNRWWGV 1410
Query 487 AAQDGGSLEVVNTDSTPTTPKTYE-------------TGY---------IHVR-DQLNND 523
DG V T P Y +G+ +H+R +L+N+
Sbjct 1411 VRHDGVEYLAVYWGKGATVPDEYRIRTGDTETVTVSASGHAARISGGADMHIRAGRLDNE 1470
Query 524 QGAIVAQGGIDLESNNGLDNQGGQ 547
I+A GG+ L S + L+NQG Q
Sbjct 1471 ASFILAGGGMTL-SGDTLNNQGWQ 1493
Score = 36.2 bits (82), Expect = 0.001
Identities = 137/652 (21%), Positives = 230/652 (35%), Gaps = 78/652 (12%)
Query 2900 GSAAATAAASSATYGFTIGANGERIETTNTTNTTQGKWQGSTLELNNLTLKSENQDVN-- 2957
G AA A+ YG T G I T + T TT + L L + + +N
Sbjct 130 GKAANVMVANP--YGITCDGCGF-INTPHATLTTGKPVMNADGSLQALEVTEGSITINGA 186
Query 2958 -VQGSR-------LTATGTTSFDGTKDLNVTAGTEHSQQETSSKTNSQSVSYTYGGGGSA 3009
+ G+R AT + KDL VTAG T VS G G
Sbjct 187 GLDGTRSDAVSIIARATEVNAALHAKDLTVTAGANRI-------TADGRVSALKGEGNVP 239
Query 3010 SIGKQTSTSESKSLTYVNSEVTLNKTEGRLNSLNIKGGEVSIQDRGNLQVNNIHVESLQD 3069
+ T ++ T + L +L + G++ + G L + N
Sbjct 240 KVAVDTGALGGMYARRIHLTSTESGVGVNLGNLYAREGDIILSSSGKLVLKNSLAGGNTT 299
Query 3070 TASSSNSSRGGSIGGGYGSGSKNITASYNQSKGSSDSAWVNTTSKLLIGN-AQNDANLDA 3128
+ S G + GG S + + NQS+ +D V ++S ++ N + A +A
Sbjct 300 VTGTDVSLSGDNKAGGNLSVTGTTGLTLNQSRLVTDKNLVLSSSGQIVQNGGELTAGQNA 359
Query 3129 M-GVKNITNIGGVIANANKNADGSLTDHKNLNYTGNLELKDLQDHNNNNSSGFNVS---- 3183
M +++ G + NA +N + TD L + N+ G V+
Sbjct 360 MLSAQHLNQTSGTV-NAAENVTLTTTDDTTLKGRSVAGKTLTVSSGSLNNGGTLVAGRDA 418
Query 3184 -------TNIGIPQG-GSKAASTAPKGSTTIGLNSSGQETE-QLTKATLG--QGSVTNAT 3232
+N G QG G K +T T+ G SG + ATL G+ A
Sbjct 419 TVKTGTFSNTGTVQGNGLKVTAT---DLTSTGSIKSGSTLDISARNATLSGDAGAKDRAL 475
Query 3233 ADTNRDINNTQEITRDQTTGMLNGSVTVDHRLLSESGRAEIVKEQEQLIENFRQSAENLA 3292
+ + N + D +L S T + + SG E+V SA+ L
Sbjct 476 VTVSGTLENRGRLVSDD---VLTLSATQINNSGTLSGAKELV-----------ASADTLT 521
Query 3293 KALPDGVYKDKALQTLNDVQAKLYNLPSEYKEVGVVGNSVASELLKRGM-ESQDVEALFS 3351
D L L+ + L S V V GNS+ + + S V+ +
Sbjct 522 TTEKSVTNSDGNLM-LDSASSTLAGETSAGGTVSVKGNSLKTTTTAQTQGNSVSVDVQNA 580
Query 3352 KLDFFYAAKEFSEI--QNQLTDLEKSGVNLETIF--KQPKAGVNEQETIYAQGTDFETKV 3407
+LD AA++ + +LT KS ++ + +GV + Q
Sbjct 581 QLDGTQAARDILTLNASEKLTHSGKSSAPSLSLSAPELTSSGVLVGSALNTQSQTLTNSG 640
Query 3408 RSQTTLGMTI------------LSNIADLGNSIKDISESTGVDIEKVQLAVGLLISGPVR 3455
Q +T+ L + ADL I DI S + + + + +S P +
Sbjct 641 LLQGKASLTVNTQRLDNQQNGTLYSAADLTLDIPDIRNSGLITGDNGLMLNAVSLSNPGK 700
Query 3456 LVIESGKSMAVDSVVGEKVAQGVDILANSMTAAAHDTSVNTINNWTNPDKIS 3507
++ ++ S+ ++ G+ + QG A ++ A S+ + W +S
Sbjct 701 IIADT-LSVRATTLDGDGLLQG----AGALALAGDTLSLGSNGRWLTAGDLS 747
Score = 23.9 bits (50), Expect = 7.5
Identities = 20/79 (25%), Positives = 31/79 (39%), Gaps = 2/79 (3%)
Query 3414 GMTILSNIADLGNSIKDISESTGVDIEKVQLAVGLLISGPVRLVIESGKSMAVDSVVGEK 3473
G I N+ NS+ + TGVD + + L +L+ ++ DSV +
Sbjct 939 GQWIAKNLTLKANSLTSAGDITGVDALTLTVNQTLNNHASGKLLSAGVLTLKADSVKNDG 998
Query 3474 VAQG--VDILANSMTAAAH 3490
QG I A +T H
Sbjct 999 QLQGNATTITAGQLTNGGH 1017
>B3BM48 tRNA nuclease CdiA [Escherichia coli O157:H7 (strain EC869)]
Length=3209
Score = 361 bits (926), Expect = 5e-102
Identities = 389/1439 (27%), Positives = 630/1439 (44%), Gaps = 193/1439 (13%)
Query 107 SSNGVTQVNIQTPSAGGVSRNTYSQFDVGQEGAILNNARNNTQ-TQLGGWIQGNPWL-AK 164
++NGV VNI TP+ G+S N ++ ++VG+EG ILNNA TQLGG IQ NP L A
Sbjct 45 AANGVPVVNIATPNGAGISHNRFTDYNVGKEGLILNNATGKLNPTQLGGLIQNNPNLKAG 104
Query 165 GEAKVILNEVNSSNPSQLKGYIEVAGKQAQVVIANPSGLVCDGCGVINADRFTLTTGQAV 224
GEAK I+NEV N S L+GY EVAGK A V++ANP G+ CDGCG IN TLTTG+ V
Sbjct 105 GEAKGIINEVTGGNRSLLQGYTEVAGKAANVMVANPYGITCDGCGFINTPHATLTTGRPV 164
Query 225 MN-QGYLESFRVREGQITIQGKGLNGSLTPFTDVYARALQVNAGLYAKELNVVLGQNDIN 283
MN G L++ V EG ITI G GL+G+ + + ARA +VNA L+AK+L V G N I
Sbjct 165 MNADGSLQALEVTEGSITINGAGLDGTRSDAVSIIARATEVNAALHAKDLTVTAGANRIT 224
Query 284 VNDPTTSNVSPIQSNTSANNKPQFALDVGQLGGMYAGKIFLVGTEQGVGVRNAGSMNSTQ 343
+ VS ++ + P+ A+D G LGGMYA +I L TE GVGV N G++ + +
Sbjct 225 AD----GRVSALKGE---GDVPKVAVDTGALGGMYARRIHLTSTESGVGV-NLGNLYARE 276
Query 344 STLTLNANGDLT-----NTGNLIANQGQLQLNAENIKNTGNIS-SATSQVSLHSQNL--D 395
+ LN+ G L GN + L+ +N K GN+S + T+ ++L+ L D
Sbjct 277 GDIILNSAGKLVLKNSLAGGNTTVTGTDVSLSGDN-KAGGNLSVTGTTGLTLNQSRLVTD 335
Query 396 NSGLISSADELNIQQQGHV--GNRGTLNAARIVVDAGSLANSGSIEQTGAQALDLKAGSM 453
+ ++SS+ ++ +Q G + G L+A + +G++ + ++ T LK S
Sbjct 336 KNLVLSSSGQI-VQNGGELTAGQNAMLSAQHLNQTSGTVNAAENVTLTTTDDTTLKGRS- 393
Query 454 SNIGGKIGIAKTSSTGGNGSESGGGSQPVE----PNNAAQDGGSLEVVNTDSTPTTPKTY 509
I GK + S G+ G V+ N G L+V TD T T
Sbjct 394 --IAGKTLTVSSGSLNNGGTLVAGRDATVKTGTFSNTGTVQGNGLKVTATDLTST----- 446
Query 510 ETGYIHVRDQLNNDQGAIVAQGGIDLESNNG-LDNQGGQLNLGRVKIQGERFNNDQGQLT 568
G+I + +D+ + N L G + RV + G N +G+L
Sbjct 447 ---------------GSIKSGSTLDISARNATLSGDAGAKDSARVTVSGTLEN--RGRLV 489
Query 569 VKQAEIQTNSLSNQSGQLISNQKLNIQTQT-ANNQKGKIQSVDQLDLNVANGLNNIEGQI 627
+ + N SG L ++L T +K S L LN A+ + + G+
Sbjct 490 SDDVLTLSATQINNSGTLSGAKELVASADTLTTTEKSVTHSDGNLMLNSAS--STLAGET 547
Query 628 ASGQQLNIQADQV------NNQSGLIYSEQQGIELKANHAINN----------TSGIIQA 671
++G ++++ + + Q + + Q +L A + T +
Sbjct 548 SAGSTVSVKGNSLKTTATAQTQGNSVSVDVQNAQLDGTQAARDILTLNASEKLTHSGKSS 607
Query 672 KTQLNLASTQLDNTSGHIQAENIQQQHTTVNNTQGSIVAGQSLISTVDQFDNHQG--LID 729
L+L++ +L +SG + + Q T+ N+ G + SL + DN Q L
Sbjct 608 APSLSLSAPEL-TSSGVLVGSALNTQSQTLTNS-GLLQGKASLTVNTQRLDNQQNGTLYS 665
Query 730 AKNIQLTHQVLNNSGSIYADQNIKITGQHILNTGSIAAGQ-NIQLNTAK---LQHEQAAL 785
A ++ L + NSG I D + + + N G I A N++ T L AL
Sbjct 666 AADLTLDIPDIRNSGLITGDNGLTLNTASLSNPGKIIADTLNVRATTLDGDGLLQGAGAL 725
Query 786 IAAG----LDRQGKLTSTGDLDITAEQT----TLHGQSFAGQQLKVASKQQIDATNGQLQ 837
AG R G+ + GDL + + T GQ+ Q A+ + AT G L
Sbjct 726 ALAGDTLSQGRNGRWLTAGDLSLRGKTLHTAGTTQGQNLTVQADNWANSGSVLAT-GNLT 784
Query 838 AKNIDLASDAGDISTRAATVIAEQLSLKSHDLIDNQQGTLSAQQLNLTANRLDN---TQG 894
A + GDI ++ T + + DN+ LSA L+L N LDN QG
Sbjct 785 ASATGQLTSTGDIMSQGDTTLNAATT-------DNRGSLLSAGTLSLDGNSLDNRGTVQG 837
Query 895 HILHTGQDQLDLNFSQSLNNQLGEIRSNAAELNIKTALLNN------------TEGQVVH 942
+ Q+ + + + + A ++ + AL+NN T G +
Sbjct 838 DHVTIRQNSVT---NSGTFTGIAALTLAARMVSPQPALMNNGGSLLTSGDLTITAGSITS 894
Query 943 AG-------------------TQQLNIQTAQLNGHL-----GHILSNG------------ 966
+G Q + TA+L G L + SNG
Sbjct 895 SGHWQGKRVLITADSLANSGAIQAADSLTARLTGELVSAAGSKVTSNGEMALSALNLSNS 954
Query 967 ------TLQLKAGTLDVSGGVTSADQITIQAN--VLNNAQGQLIQRGTSNPLNLTIQQQL 1018
L LKA +L +G +T D +T+ N + N+A G+L+ G LT++
Sbjct 955 GQWIAKNLTLKANSLTSAGDITGVDALTLTVNQTLNNHASGKLLSAGV-----LTLKADS 1009
Query 1019 NNQAGLIQSATATDIKAGSLNNQRGTLSSAQGQNLDVDVAGKLDNSQSGQIYAGNQAHLQ 1078
G +Q AT I AG L N QG+ L + +G ++N G + + N ++
Sbjct 1010 VTNDGQLQ-GNATTITAGQLTNG----GHLQGETLTLTASGGVNNRSGGVLMSRNALNVS 1064
Query 1079 VGSIDNSHQGQINAQQNLQLTSQQQINNQSGQIVANGDVQIQSQGLNNSHGQMGSLQGGL 1138
++ N QG I + L + ++ N G+I++ ++ + +Q L N+ G +Q
Sbjct 1065 TATLSN--QGTIQGGGGVSLNATDRLQN-DGKILSGSNLTLTAQVLANTGS--GLVQAAT 1119
Query 1139 SLNTGSDTLINQSGLIQAKKDIGIQAQRIDNQQGQITTQGQAELISQAEIDNLEGAIAAD 1198
L +T+ G + A ++ ++N T QG L++ N G +
Sbjct 1120 LLLDVVNTV--NGGRVLATGSADVKGTTLNNTG---TLQGADLLVNYHTFSN-SGTLLGT 1173
Query 1199 LDVNIR-SQGLNNNKGQISSAQGNLTLNAGNGTLTNQAATIVSGK-TLTLSANQLDNSNH 1256
+ ++ S L N G++ SA GNL L+A + + Q + +G TL L A +NH
Sbjct 1174 SGLGVKGSSLLQNGTGRLYSA-GNLLLDAQD--FSGQGQVVATGDVTLKLIAAL---TNH 1227
Query 1257 GQINSQNNADISIVKDINNTSGVIAAKQQLILSSQGLNNTTGQIGTVQGNLHIDAGSQLL 1316
G + + ++ I N GV+ ++ + + N G + +GN + + +L
Sbjct 1228 GTLAAGKTLSVTSQNAITN-GGVMQGDAMVLGAGEAFTN-NGMLTAGKGN-SVFSAQRLF 1284
Query 1317 NNQQGRIQSGQDLNLNATGIDNTQGQISSKNQLQLDSREQLLNNRQGTLSAENLTIDSGE 1376
N G +Q+G D++LN+ G + L ++ LLN+ + NL + +
Sbjct 1285 LNAPGSLQAGGDVSLNSRSDITISGFTGTAGSLTMNVAGTLLNSAL-IYAGNNLKLFTDR 1343
Query 1377 LNNDQGLIQAQQSIQIDTHQHNLSNTNSGAQGGIL--SQGNIQLNNIQTLDNQQGYLAS 1433
L+N G I A S+ + +N+ + G + ++G+I +N L++ AS
Sbjct 1344 LHNQHGDILAGNSLWVQKDSSGTANSEIINRSGNIETTRGDITMNTAHLLNSWDAISAS 1402
Score = 327 bits (837), Expect = 1e-91
Identities = 632/2784 (23%), Positives = 1052/2784 (38%), Gaps = 436/2784 (16%)
Query 543 NQGGQLNLGRVKIQGERFNNDQGQLTVKQAEIQTNSLSNQSGQLISNQKLNIQTQTANNQ 602
N+ N+G+ +G NN G+L Q G LI N N +
Sbjct 65 NRFTDYNVGK---EGLILNNATGKLN-----------PTQLGGLIQN---NPNLKAGGEA 107
Query 603 KGKIQSVDQLDLNVANGLNNIEGQIASGQQLNIQADQVNNQSGLIYSEQQGIELKANHAI 662
KG I V + ++ G + G+ A+ N + G + L +
Sbjct 108 KGIINEVTGGNRSLLQGYTEVAGKAANVMVANPYGITCD---GCGFINTPHATLTTGRPV 164
Query 663 NNTSGIIQA----KTQLNLASTQLDNTSGHIQAENIQQQHTTVNNTQGS----IVAGQSL 714
N G +QA + + + LD T A +I + T VN + + AG +
Sbjct 165 MNADGSLQALEVTEGSITINGAGLDGTRS--DAVSIIARATEVNAALHAKDLTVTAGANR 222
Query 715 ISTVDQFDNHQGLIDAKNIQLTHQVLNNSGSIYADQNIKITGQHILNTGSIAAGQNIQLN 774
I+ + +G D + + L G +YA + I +T S +G + L
Sbjct 223 ITADGRVSALKGEGDVPKVAVDTGAL---GGMYA-RRIHLT--------STESGVGVNLG 270
Query 775 TAKLQHEQAALIAAGLDRQGKLTSTGDLDITAEQTTLHGQSFAGQQLKVASKQQIDATNG 834
+ L +AG + G+ +T +L G + AG L V +
Sbjct 271 NLYAREGDIILNSAGKLVLKNSLAGGNTTVTGTDVSLSGDNKAGGNLSVTGTTGLTLNQS 330
Query 835 QLQAKNIDLASDAGDISTRAATVIAEQLSLKSHDLIDNQQGTLSAQQLNLTANRLDNTQG 894
+L + S +G I + A Q ++ S ++ GT++A + N+T D+T
Sbjct 331 RLVTDKNLVLSSSGQIVQNGGELTAGQNAMLSAQHLNQTSGTVNAAE-NVTLTTTDDTTL 389
Query 895 HILHTGQDQLDLNFSQSLNNQLGEIRSNAAELNIKTALLNNTEGQVVHAGTQQLNIQTAQ 954
L ++ S SLNN G + +KT +NT G V G L +
Sbjct 390 KGRSIAGKTLTVS-SGSLNN--GGTLVAGRDATVKTGTFSNT-GTVQGNG---LKVTATD 442
Query 955 LNGHLGHILSNGTLQLKAGTLDVSGGVTSADQITIQANVLNNAQGQLIQRGTSNPLNLTI 1014
L G I S TL + A +SG + D + + +G+L+ LT+
Sbjct 443 LTS-TGSIKSGSTLDISARNATLSGDAGAKDSARVTVSGTLENRGRLVSDDV-----LTL 496
Query 1015 QQQLNNQAGLIQSATATDIKAGSLNNQRGTLSSAQGQNLDVDVAGKLDNSQSGQIYAGNQ 1074
N +G + A A +L +++ + G NL ++ A ++ +G+ AG+
Sbjct 497 SATQINNSGTLSGAKELVASADTLTTTEKSVTHSDG-NLMLNSAS---STLAGETSAGST 552
Query 1075 AHLQVGSIDNSHQGQINAQ------QNLQLTSQQQIN-----NQSGQIVANGDVQIQSQG 1123
++ S+ + Q QN QL Q N S ++ +G S
Sbjct 553 VSVKGNSLKTTATAQTQGNSVSVDVQNAQLDGTQAARDILTLNASEKLTHSGKSSAPSLS 612
Query 1124 LNNSHGQMGSLQGGLSLNTGSDTLINQSGLIQAKKDIGIQAQRIDNQQGQITTQGQAELI 1183
L+ + G +LNT S TL N SGL+Q K + + QR+DNQQ T A+L
Sbjct 613 LSAPELTSSGVLVGSALNTQSQTLTN-SGLLQGKASLTVNTQRLDNQQNG-TLYSAADLT 670
Query 1184 SQAEIDNLEGAIAADLDVNIRSQGLNNNKGQISSAQGNL--TLNAGNGTLTNQAATIVSG 1241
G I D + + + L+N G+I + N+ T G+G L A ++G
Sbjct 671 LDIPDIRNSGLITGDNGLTLNTASLSN-PGKIIADTLNVRATTLDGDGLLQGAGALALAG 729
Query 1242 KTLTLSANQLDNSNHGQINSQNNADISIVKDINNTSGVIAAKQQLILSSQGLNNTTGQIG 1301
TL+ N D+S+ +T+G Q L + + N+ +
Sbjct 730 DTLSQGRNG---------RWLTAGDLSLRGKTLHTAGTTQG-QNLTVQADNWANSGSVLA 779
Query 1302 TVQGNLHIDAGSQLLNNQQGRIQSGQDLNLNATGIDNTQGQISSKNQLQLDSREQLLNNR 1361
T GNL A QL + G I S D LNA DN +G + S L LD L+NR
Sbjct 780 T--GNLTASATGQLTST--GDIMSQGDTTLNAATTDN-RGSLLSAGTLSLDGNS--LDNR 832
Query 1362 QGTLSAENLTIDSGELNND---QGLIQAQQSIQIDTHQHNLSNTNSG---------AQGG 1409
GT+ +++TI + N G+ + ++ + Q L N G
Sbjct 833 -GTVQGDHVTIRQNSVTNSGTFTGIAALTLAARMVSPQPALMNNGGSLLTSGDLTITAGS 891
Query 1410 ILSQGNIQLNNIQ-TLDN--QQGYLASAQQLDLQ--------ANQVFNQNGTLLAAKQLN 1458
I S G+ Q + T D+ G + +A L + A NG + A LN
Sbjct 892 ITSSGHWQGKRVLITADSLANSGAIQAADSLTARLTGELVSAAGSKVTSNGEM-ALSALN 950
Query 1459 LQGTGQ-----------------------------NQLLNNQ-SGQMLSMGGMNLNIDQI 1488
L +GQ NQ LNN SG++LS G + L D +
Sbjct 951 LSNSGQWIAKNLTLKANSLTSAGDITGVDALTLTVNQTLNNHASGKLLSAGVLTLKADSV 1010
Query 1489 NNKGKANTADADSHIMAAGELNITTQQLDNQNTLNTDPANTSIQG----------IDANT 1538
N G+ + IT QL N L + + G + N
Sbjct 1011 TNDGQ----------LQGNATTITAGQLTNGGHLQGETLTLTASGGVNNRSGGVLMSRNA 1060
Query 1539 LNVTSKVLNNQSGVIRSSADQNLNVQQALNNQSGQISSEKQLTLVGDQLEINNLNGQILA 1598
LNV++ L+NQ G I+ +LN L N G+I S LTL Q+ N +G + A
Sbjct 1061 LNVSTATLSNQ-GTIQGGGGVSLNATDRLQND-GKILSGSNLTLTA-QVLANTGSGLVQA 1117
Query 1599 GTALDLIAQSLSGDGKLLSLGNA--KLSLQNDYIHSSGAQLQANQDL-----------SL 1645
T L + +++G G++L+ G+A K + N+ GA L N L
Sbjct 1118 ATLLLDVVNTVNG-GRVLATGSADVKGTTLNNTGTLQGADLLVNYHTFSNSGTLLGTSGL 1176
Query 1646 STKGN-IINNGT---INAGNQL-----------ALNAANITNQQAGKIESHDT------- 1683
KG+ ++ NGT +AGN L + ++T + + +H T
Sbjct 1177 GVKGSSLLQNGTGRLYSAGNLLLDAQDFSGQGQVVATGDVTLKLIAALTNHGTLAAGKTL 1236
Query 1684 RLTAQNTLNNTGLINGDFTRLQA-ETLNNQG---TGRIYGTTLAIQANTLNNQPDS--TG 1737
+T+QN + N G++ GD L A E N G G+ G ++ N P S G
Sbjct 1237 SVTSQNAITNGGVMQGDAMVLGAGEAFTNNGMLTAGK--GNSVFSAQRLFLNAPGSLQAG 1294
Query 1738 TAPVIASRGDLHLG--VQTLNNLSNPTDYT--SQALIFSAGNLYL--------------G 1779
+ SR D+ + T +L+ T + ALI++ NL L G
Sbjct 1295 GDVSLNSRSDITISGFTGTAGSLTMNVAGTLLNSALIYAGNNLKLFTDRLHNQHGDILAG 1354
Query 1780 AALDANDYATGQADV-IHNESATIESL-GDMNLS-AKQINNINKYFKTEQV--------- 1827
+L ++G A+ I N S IE+ GD+ ++ A +N+ + + +V
Sbjct 1355 NSLWVQKDSSGTANSEIINRSGNIETTRGDITMNTAHLLNSWDAISASHEVIPGSSHGVI 1414
Query 1828 ----------EVSRKDGLEKYCDAWCTFDGNYYDGNPYEDWMRYYYSEITYETRTTESAP 1877
V R DG+E W +G D R + T +
Sbjct 1415 SPVPENNRWWGVVRHDGVEYLAVYWG-------EGATVPDEYRIRTGDTETVTVSASGHA 1467
Query 1878 GQIKAGGHLDLNGAQVVNDKSQILAGGELKNEGGTIDS-----GTQIAGIRKIVNTGTQV 1932
+I G + + ++ N+ S ILAGG + G T+++ GT + +G+
Sbjct 1468 ARISGGADMHIRAGRLDNEASFILAGGSMTLSGDTLNNQGWQEGTTGKETVWRLASGSLP 1527
Query 1933 KYWKYEGQWDNPFENSSETTFDLSISQALGNQNLNQNQLSTVAVSNNQSAEHIQNSQTTQ 1992
K W + W + S + S + G + S V+ S + T
Sbjct 1528 KAW-FTEPWYKVYRQVSTDATEASGTSPAGQYRAVISAASDVSASFATDT----GNTTVM 1582
Query 1993 QEINGLQTSNNNTQLNQTKDVDLDQLNLKDSQSQNAPQASAVETVQQQSATSAPSSTPQG 2052
G + LN + Q + N V + P
Sbjct 1583 PRAGGAGNTITVPSLNSLTPPTVSQ-GVSGEALLNESGTGITGPVWNDALPDTLKDIPGA 1641
Query 2053 TSEEIRSIDFSNIKVPNSALYKVNADSKAGYLI--------------------------- 2085
S S+ + N+ + + D + YLI
Sbjct 1642 LSLSGASVSSYPLPSGNNGYFVPSTDPDSPYLITVNPKLDGLGKVDSSLFAGLYDLLRMQ 1701
Query 2086 ------ETDPAFADYKKWLSSDYMLDALGLDPALQQKRLGDGFYEQRLVQDQIANLTGYR 2139
ETDPA+ D K++L S Y+LD LGL P + LGD ++ R V + I N TG R
Sbjct 1702 PGQAPRETDPAYTDEKQFLGSSYILDRLGLKPEKDYRFLGDAAFDTRYVSNVILNQTGSR 1761
Query 2140 FLEGFANDDEQYKALMNNGITFAKLYGLRPGIALTAAQTAQLTSDIVWLVEQSVTLPDGT 2199
++ G +D Q K LM++ K GL G++LTA Q AQLT I+W +SVT+ T
Sbjct 1762 YINGTGSDLAQMKYLMDSAAAQQKALGLTFGVSLTAGQVAQLTRSILWW--ESVTINGQT 1819
Query 2200 ITKALVPQVYVKVRVGDLKGDGTLLSGNSVNLKLDGDLIN--GATIAGREALQITADNVQ 2257
+ +VP++Y+ L +G+++SGN+V L G++ N G+ A + L + ++
Sbjct 1820 V---MVPKLYLSPEDITLH-NGSVISGNNVQL-AGGNITNSGGSINAQNDLLLDSTGSID 1874
Query 2258 NLNGRI--QGNQVAIETQKDLNNIGGQIIAKDAMALKVGGNLNIESTTRTSESKVGNFSS 2315
NLN + G + ++ D+ NI I K G NI + TRT + + N +
Sbjct 1875 NLNAGLINAGGALNLKAIGDIGNISSVISGKTVSLESATG--NISNLTRTEQWAMNNGYN 1932
Query 2316 SITNVDRVAGLYVGNGSTKQLDPNQAT--LMLNVAGNSSLKGVQINNSNSATVLNTTGNV 2373
+ D T L +AT L + AG+ S+ G ++ +S VL + GN
Sbjct 1933 HFSGTD-----------TGPLAAVRATDSLFMGAAGDISITGAAVSAGDS--VLLSAGN- 1978
Query 2374 DLGTVSVGKQETLKIDDKNGYQLKQQQDVGSQIKSAGSLLINGQNITSKAVDLNSQQGDI 2433
DL ++ E + Y + V + + SL++ S D+NSQ I
Sbjct 1979 DLNMNAIQAGERRRYGGSGWY---ETHAVAPTVTAGNSLML------SAGRDVNSQAAGI 2029
Query 2434 QLSAQKDIVLDNGLNQSTVSSQSQSKGSFGGKKSSTYDASSSTSIANQLNAGQNIIINSA 2493
DI +N ++++S G S S + +G +I + +
Sbjct 2030 MAENSMDIRAGRDVN---MAAESTGTGDHDSTFSMKTVHDSVRQQGTDMTSGGDITVTAG 2086
Query 2494 QGNISATHLQAEAGNNIQIHAQQGNVTLLSAIDDKRESSTSSKKGVATYNNRQSGYIDQE 2553
+ +I++ A +I+++A ++ L +A + S S + +++ + I ++
Sbjct 2087 R-DITSVATAVTAKGDIRVNAGH-DIVLGTATESDYHYSESGETRNRLLSHQTTRTITED 2144
Query 2554 VA---QTTLKAGDTVDINAAKNIELQANDVQAGNSIYVGNTLMQRQADGSLKAADGSLMP 2610
+ +L +G+ V ++A N+ ++ +DV A D SL A +
Sbjct 2145 SVTREKGSLLSGNRVTVDAGDNLTVEGSDVVA-------------DRDVSLAAGN----- 2186
Query 2611 ENVTLSTLATKDEQWDEQQKGYRGIVKDIVKATAVGLAGIEALAPGLKAPKITVSESTGK 2670
+V + + D W K+ K+ GL G + + + K T
Sbjct 2187 -HVDVLAATSTDTSWR---------FKETKKS---GLMGTGGIGFTIGSSKTTHDRREAG 2233
Query 2671 RTEQISQTGSSLKADNVYVGSSGQTTLTSTDITAKNTI-LLGQKVTLNAAEEQKITVEST 2729
T+ S + A NV + + Q ++ +D+ A I + G V ++ +++ TV+
Sbjct 2234 TTQSQSASTIGSTAGNVSITAGKQAHISGSDVIANRDISITGDSVVVDPGHDRR-TVDEK 2292
Query 2730 SKETVQGLGAKLNKDSIRLGGFVLEDASQSSKTTETT-HKLGSINTENLKIQGVEGVDIL 2788
++ GL L S +G + + + +T E++ +L ++ + GV+
Sbjct 2293 FEQKKSGLTVAL---SGTVGSAINNAVTSAQETKESSDSRLKALQATKTALSGVQAGQAA 2349
Query 2789 GQNITATGDTLIDHGRGDLNVGGYENKTTVEDKTHVETISTEVGVRNAYLDAALALGAVK 2848
TATGD N G T + K+ + S V + L+A L V
Sbjct 2350 AM-ATATGDP---------NATGVSLSLTTQ-KSKSQQHSESDTVSGSTLNAGNNLSVVA 2398
Query 2849 DAAEAVKQAKDQYSQAQRDYASGKITKEALDDSKANVAMATANLANAQIAVGSAAATAAA 2908
D + A G + +A +D + + AN Q G +++
Sbjct 2399 TGKNRGDNRGDIVIAGSQLKAGGNTSLDAAND------VLLSGAANTQKTTGRNSSSGGG 2452
Query 2909 SSATYGFTIGANGERIETTNTTNTTQGKWQGSTLELNNLTLKSENQDVNVQGSRLTATGT 2968
+ G G NG I + N +G +G+ E T+ S + V + R T
Sbjct 2453 VGVSIG--AGGNGAGISVFASVNAAKGSEKGNGTEWTETTIDS-GKTVTINSGRDTVLNG 2509
Query 2969 TSFDGTKDLNVTAGTEH-----SQQETSSKTNSQSVSYTYGGGGSASIGKQT-------S 3016
+G + + A H SQQ+TS + Q+ + GGS + G T S
Sbjct 2510 AQVNGNR---IIADVGHDLLISSQQDTSKYDSKQT---SVAAGGSFTFGSMTGSGYIAAS 2563
Query 3017 TSESKSLTYVNSEVT--------LNKTEGRLNSLN-IKGGEVSIQDRGNLQVNNIHVESL 3067
+ KS +E T + T GR L+ + D+ +L + L
Sbjct 2564 RDKMKSRFDSVAEQTGMFAGDGGFDITVGRHTQLDGAVIASTATPDKNHLDTGTLGFSDL 2623
Query 3068 QDTASSSNSSRGGSIGGGYGSGSK 3091
+ A S G S+ GG G K
Sbjct 2624 HNEADYKVSHSGISLSGGGSFGDK 2647
Score = 109 bits (273), Expect = 8e-26
Identities = 227/971 (23%), Positives = 386/971 (40%), Gaps = 194/971 (20%)
Query 2349 GNSSLKGVQINNSNSATVLNTTGNVD---LGTVSVGKQETLKIDDKNGYQLKQQQDVGSQ 2405
GN + G IN N +L++TG++D G ++ G LK D+G+
Sbjct 1850 GNITNSGGSINAQNDL-LLDSTGSIDNLNAGLINAG----------GALNLKAIGDIGN- 1897
Query 2406 IKSAGSLLINGQNITSKAVDLNSQQGDIQ-LSAQKDIVLDNGLNQSTVSSQSQSKGSFGG 2464
I S I+ K V L S G+I L+ + ++NG N F G
Sbjct 1898 ISSV---------ISGKTVSLESATGNISNLTRTEQWAMNNGYNH------------FSG 1936
Query 2465 KKSSTYDASSSTSIANQLNAGQNIIINSAQGNISATHLQAEAGNNIQIHAQQGNVTLLSA 2524
+ A +T + + A G+IS T AG+++ + A GN ++A
Sbjct 1937 TDTGPLAAVRAT----------DSLFMGAAGDISITGAAVSAGDSVLLSA--GNDLNMNA 1984
Query 2525 IDDKRESSTSSKKGVATYNNRQSGYIDQEVAQTTLKAGDTVDINAAKNIELQANDVQAGN 2584
I ++ + G SG+ + T+ AG+++ ++A +++ QA + A N
Sbjct 1985 I----QAGERRRYG-------GSGWYETHAVAPTVTAGNSLMLSAGRDVNSQAAGIMAEN 2033
Query 2585 SIYVG---NTLMQRQADG--------SLKAADGSLMPENVTLST------LATKDEQWDE 2627
S+ + + M ++ G S+K S+ + +++ A +D
Sbjct 2034 SMDIRAGRDVNMAAESTGTGDHDSTFSMKTVHDSVRQQGTDMTSGGDITVTAGRDITSVA 2093
Query 2628 QQKGYRGIVK-----DIVKATAVGLAGIEALAPGLKAPKITVSESTGKRTEQ--ISQTGS 2680
+G ++ DIV TA + G ++ ++T TE + GS
Sbjct 2094 TAVTAKGDIRVNAGHDIVLGTATE-SDYHYSESGETRNRLLSHQTTRTITEDSVTREKGS 2152
Query 2681 SLKADNVYVGSSGQTTLTSTDITAKNTILL--GQKVTLNAAEEQKIT--VESTSKETVQG 2736
L + V V + T+ +D+ A + L G V + AA + + T K + G
Sbjct 2153 LLSGNRVTVDAGDNLTVEGSDVVADRDVSLAAGNHVDVLAATSTDTSWRFKETKKSGLMG 2212
Query 2737 LG--------AKLNKDSIRLGGFVLEDASQSSKTTETTHKLGSINTENLKIQGVEGVDIL 2788
G +K D G SQS+ T +T G+++ K + G D++
Sbjct 2213 TGGIGFTIGSSKTTHDRREAG----TTQSQSASTIGST--AGNVSITAGKQAHISGSDVI 2266
Query 2789 G-QNITATGDTLIDHGRGDLNVGGYENKTTVEDKTHVETISTEVGVRNAYLDAALALGAV 2847
++I+ TGD+++ V ++ TV++K + V + A+
Sbjct 2267 ANRDISITGDSVV--------VDPGHDRRTVDEKFEQKKSGLTVALSGT---VGSAINNA 2315
Query 2848 KDAAEAVKQAKDQYSQAQRDYASGKITKEALDDSKANVAMATANLANAQIAVGSAAATAA 2907
+A+ K++ D +A + TK AL +A A A A A G AT
Sbjct 2316 VTSAQETKESSDSRLKALQ------ATKTALSGVQAGQAAAMAT------ATGDPNATGV 2363
Query 2908 ASSATYGFTIGANGERIETTNTTNTTQGKWQGSTLEL-NNLTL------KSENQ-DVNVQ 2959
+ S T T + ++ ++T + GSTL NNL++ + +N+ D+ +
Sbjct 2364 SLSLT---TQKSKSQQHSESDTVS-------GSTLNAGNNLSVVATGKNRGDNRGDIVIA 2413
Query 2960 GSRLTATGTTSFDGTKD--LNVTAGTEHSQQETSSKTNSQSVSYTYGGGGS--------- 3008
GS+L A G TS D D L+ A T+ + SS VS GG G+
Sbjct 2414 GSQLKAGGNTSLDAANDVLLSGAANTQKTTGRNSSSGGGVGVSIGAGGNGAGISVFASVN 2473
Query 3009 ASIGKQTSTSESKSLTYVNSEVTLNKTEGR---LNSLNIKGGEVSIQDRGNLQVNNIHVE 3065
A+ G + + T ++S T+ GR LN + G + I D G+ ++ +
Sbjct 2474 AAKGSEKGNGTEWTETTIDSGKTVTINSGRDTVLNGAQVNGNRI-IADVGH----DLLIS 2528
Query 3066 SLQDTAS----SSNSSRGGSIGGGYGSGSKNITASYNQSKGSSDSAWVNTTSKLLIGNAQ 3121
S QDT+ ++ + GGS G +GS I AS ++ K DS T G
Sbjct 2529 SQQDTSKYDSKQTSVAAGGSFTFGSMTGSGYIAASRDKMKSRFDSVAEQT------GMFA 2582
Query 3122 NDANLDAMGVKNITNIGGVIANANKNADGSLTDHKNLNYTGNLELKDLQDHNNNNSSGFN 3181
D D ++ G VIA+ + T KN TG L DL +N + +
Sbjct 2583 GDGGFDITVGRHTQLDGAVIAS-------TATPDKNHLDTGTLGFSDL-----HNEADYK 2630
Query 3182 VS-TNIGIPQGGS---KAASTAPKGSTTIGLNSSGQETEQLTKATLGQGSVTNATADTNR 3237
VS + I + GGS K P G + G +S E T+A + +G++T D +
Sbjct 2631 VSHSGISLSGGGSFGDKFQGNMPGGMISAGGHSG--HAEGTTQAAVAEGTITIRDRDNQK 2688
Query 3238 DINNTQEITRD 3248
N ++RD
Sbjct 2689 --QNLANLSRD 2697
Score = 70.9 bits (172), Expect = 5e-14
Identities = 218/1064 (20%), Positives = 381/1064 (36%), Gaps = 134/1064 (13%)
Query 2172 ALTAAQTAQLTSDIVWLVEQSV--TLPDGTITKALVPQVYVKVRVGDLKGDGTLLSGNSV 2229
A+ +AQ TS V E T D T+ + + V G L GTL++G
Sbjct 359 AMLSAQHLNQTSGTVNAAENVTLTTTDDTTLKGRSIAGKTLTVSSGSLNNGGTLVAGRDA 418
Query 2230 NLKLDGDLINGATIAGREALQITADNVQNLNGRIQGNQVAIETQKDLNNIGGQIIAKDAM 2289
+K G N T+ G L++TA ++ + G+ + I + + G AKD+
Sbjct 419 TVKT-GTFSNTGTVQGN-GLKVTATDLTSTGSIKSGSTLDISARNA--TLSGDAGAKDSA 474
Query 2290 ALKVGGNLN------IESTTRTSESKVGNFSSSITNVDRVAGLYVGNGSTKQLDPNQATL 2343
+ V G L + S +++ N + + VA + K + + L
Sbjct 475 RVTVSGTLENRGRLVSDDVLTLSATQINNSGTLSGAKELVASADTLTTTEKSVTHSDGNL 534
Query 2344 MLNVAGNS-----------SLKGVQINNSNSATVLNTTGNVDLGTVSV-GKQETLKIDDK 2391
MLN A ++ S+KG + + +A + +VD+ + G Q I
Sbjct 535 MLNSASSTLAGETSAGSTVSVKGNSLKTTATAQTQGNSVSVDVQNAQLDGTQAARDILTL 594
Query 2392 NGYQLKQQQDVGSQIKSAGSLLINGQNITSKAVDLNSQQGDIQLSAQKDIVLDNGLNQST 2451
N ++ S SA SL ++ +TS V + S L+ Q + ++GL Q
Sbjct 595 NA----SEKLTHSGKSSAPSLSLSAPELTSSGVLVGSA-----LNTQSQTLTNSGLLQGK 645
Query 2452 VSSQSQSKGSFGGKKSSTYDASSST-SIANQLNAGQNIIINSAQGNISATHLQAEAGNNI 2510
S ++ + + Y A+ T I + N+G G+ T A N
Sbjct 646 ASLTVNTQRLDNQQNGTLYSAADLTLDIPDIRNSGL------ITGDNGLTLNTASLSNPG 699
Query 2511 QIHAQQGNV--TLLSAIDDKRESSTSSKKGVATYNNRQSGYIDQEVAQTTLKAGDTVDIN 2568
+I A NV T L + + + G R ++ K T
Sbjct 700 KIIADTLNVRATTLDGDGLLQGAGALALAGDTLSQGRNGRWLTAGDLSLRGKTLHTAGTT 759
Query 2569 AAKNIELQAND-VQAGNSIYVGNTLMQRQADGSLKAADGSLMPENVTLSTLATKDEQW-- 2625
+N+ +QA++ +G+ + GN + A G L + G +M + T AT D +
Sbjct 760 QGQNLTVQADNWANSGSVLATGN--LTASATGQLTST-GDIMSQGDTTLNAATTDNRGSL 816
Query 2626 --------DEQQKGYRGIVKD---IVKATAVGLAGIEALAPGLKAPKITVSESTGKRTEQ 2674
D RG V+ ++ +V +G G+ A +T++
Sbjct 817 LSAGTLSLDGNSLDNRGTVQGDHVTIRQNSVTNSGTFT---GIAA--LTLAARMVSPQPA 871
Query 2675 ISQTGSSLKADNVYVGSSGQTTLTSTDITAKNTILLGQKVTLNAAEEQKITVESTSKETV 2734
+ G SL +SG T+T+ IT+ G++V + A S + +
Sbjct 872 LMNNGGSLL-------TSGDLTITAGSITSSGH-WQGKRVLITADS----LANSGAIQAA 919
Query 2735 QGLGAKLNKDSIRLGGFVLEDASQSSKTTETTHKLGSINTENLKIQG--------VEGVD 2786
L A+L + + G + + + + G +NL ++ + GVD
Sbjct 920 DSLTARLTGELVSAAGSKVTSNGEMALSALNLSNSGQWIAKNLTLKANSLTSAGDITGVD 979
Query 2787 ILGQNITATGDTLIDHGRGDLNVGGYENKTTVEDKTHVETISTEVGVRNAYLDAALALGA 2846
L + TL +H G L G V T+ + V N D L A
Sbjct 980 ALTLTVN---QTLNNHASGKLLSAG------------VLTLKAD-SVTN---DGQLQGNA 1020
Query 2847 VKDAAEAVKQAKDQYSQAQRDYASGKITKEA----LDDSKANVAMATANLANAQIAVGSA 2902
A + + ASG + + + + NV+ AT + G
Sbjct 1021 TTITAGQLTNGGHLQGETLTLTASGGVNNRSGGVLMSRNALNVSTATLSNQGTIQGGGGV 1080
Query 2903 AATAAASSATYGFTIGANGERIETTNTTNTTQGKWQGSTLELNNLTLKSENQDVNVQGSR 2962
+ A G + + + NT G Q +TL L+ + V G R
Sbjct 1081 SLNATDRLQNDGKILSGSNLTLTAQVLANTGSGLVQAATLLLDVVN--------TVNGGR 1132
Query 2963 LTATGTTSFDGTKDLNVTAGTEHSQQETSSKT--NSQSVSYTYGGGGSASIGKQTSTSES 3020
+ ATG+ GT LN T + + + T NS ++ T G G S Q T
Sbjct 1133 VLATGSADVKGTT-LNNTGTLQGADLLVNYHTFSNSGTLLGTSGLGVKGSSLLQNGTGR- 1190
Query 3021 KSLTYVNSEVTLNKTEGRLNSLNIKGGEVSIQ------DRGNLQVNNIHVESLQDTASSS 3074
Y + L+ + + G+V+++ + G L + Q+ ++
Sbjct 1191 ---LYSAGNLLLDAQDFSGQGQVVATGDVTLKLIAALTNHGTLAAGKTLSVTSQNAITNG 1247
Query 3075 NSSRGGSIGGGYGSGSKN---ITASYNQSKGSSDSAWVNTTSKLLIGNAQNDANLDAMGV 3131
+G ++ G G N +TA S S+ ++N L G D +L++
Sbjct 1248 GVMQGDAMVLGAGEAFTNNGMLTAGKGNSVFSAQRLFLNAPGSLQAGG---DVSLNSRSD 1304
Query 3132 KNITNIGGVIANANKNADGSLTDHKNLNYTGNLELKDLQDHNNN 3175
I+ G + N G+L + + NL+L + HN +
Sbjct 1305 ITISGFTGTAGSLTMNVAGTLLNSALIYAGNNLKLFTDRLHNQH 1348
Score = 70.5 bits (171), Expect = 6e-14
Identities = 223/1040 (21%), Positives = 389/1040 (37%), Gaps = 150/1040 (14%)
Query 2231 LKLDGDL----INGATIAGREALQITADNVQNLNGRIQGNQVAIETQKDLNNIGGQIIAK 2286
LK +GD+ ++ + G A +I + ++ G GN A E LN+ G+++ K
Sbjct 232 LKGEGDVPKVAVDTGALGGMYARRIHLTSTESGVGVNLGNLYAREGDIILNS-AGKLVLK 290
Query 2287 DAMA----------------LKVGGNLNIESTTRTSESKVGNFSSSITNVDRV---AGLY 2327
+++A K GGNL++ TT + N S +T+ + V +G
Sbjct 291 NSLAGGNTTVTGTDVSLSGDNKAGGNLSVTGTTGLTL----NQSRLVTDKNLVLSSSGQI 346
Query 2328 VGNG-----------STKQLDPNQAT------LMLNVAGNSSLKGVQINNSN---SATVL 2367
V NG S + L+ T + L +++LKG I S+ L
Sbjct 347 VQNGGELTAGQNAMLSAQHLNQTSGTVNAAENVTLTTTDDTTLKGRSIAGKTLTVSSGSL 406
Query 2368 NTTGNVDLG---TVSVGKQETLKIDDKNGYQLKQQQDVGS-QIKSAGSLLINGQNITSKA 2423
N G + G TV G NG ++ + IKS +L I+ +N T
Sbjct 407 NNGGTLVAGRDATVKTGTFSNTGTVQGNGLKVTATDLTSTGSIKSGSTLDISARNATLSG 466
Query 2424 VDLNSQQGDIQLSAQKD----IVLDNGLNQSTVSSQSQSKGSFGGKKSSTYDASSSTSIA 2479
+ +S + +V D+ L S ++Q + G+ G K A + T+
Sbjct 467 DAGAKDSARVTVSGTLENRGRLVSDDVLTLS--ATQINNSGTLSGAKELVASADTLTTTE 524
Query 2480 NQL-NAGQNIIINSAQ----GNISATHLQAEAGNNIQIHA---QQGNVTLLSAIDDKRES 2531
+ ++ N+++NSA G SA + GN+++ A QGN + + + +
Sbjct 525 KSVTHSDGNLMLNSASSTLAGETSAGSTVSVKGNSLKTTATAQTQGNSVSVD-VQNAQLD 583
Query 2532 STSSKKGVATYNNRQSGYIDQEVAQTTLKAGDTVDINAAKNIELQANDVQAGNSIYVGNT 2591
T + + + T N +++ + + ++ ++A EL ++ V G+++ NT
Sbjct 584 GTQAARDILTLN------ASEKLTHSGKSSAPSLSLSAP---ELTSSGVLVGSAL---NT 631
Query 2592 LMQRQADGSLKAADGSLMPENVTLSTLATKDEQWDEQQKGYRGIVKDI-VKATAVGLAGI 2650
Q + L SL T++T ++ D QQ G D+ + + +G+
Sbjct 632 QSQTLTNSGLLQGKASL-----TVNT-----QRLDNQQNGTLYSAADLTLDIPDIRNSGL 681
Query 2651 EALAPGLKAPKITVSESTGKRTEQISQTGSSLKADNVYVGSSGQTTLTSTDITAKNTILL 2710
GL ++S + ++ ++L D + G+ T +N
Sbjct 682 ITGDNGLTLNTASLSNPGKIIADTLNVRATTLDGDGLLQGAGALALAGDTLSQGRN---- 737
Query 2711 GQKVTLNAAEEQKITVESTSKETVQGLGAKLNKDSIRLGGFVLEDASQSSKTTETTHKLG 2770
G+ +T + T+ + T QG + D+ G VL + ++ T G
Sbjct 738 GRWLTAGDLSLRGKTLHTAG--TTQGQNLTVQADNWANSGSVLATGNLTASATGQLTSTG 795
Query 2771 SINTENLKIQGVEGVDILGQNITATGDTLIDHGRGDLNVGGYENKTTVEDK--THVETIS 2828
I + +G L T +L+ G L+ +N+ TV+ T +
Sbjct 796 DIMS--------QGDTTLNAATTDNRGSLLSAGTLSLDGNSLDNRGTVQGDHVTIRQNSV 847
Query 2829 TEVGVRNAYLDAALALGAVKDAAEAVKQAKDQYSQAQRDYASGKITKEALDDSKANVAMA 2888
T G LA V + + +G IT K V +
Sbjct 848 TNSGTFTGIAALTLAARMVSPQPALMNNGGSLLTSGDLTITAGSITSSGHWQGK-RVLIT 906
Query 2889 TANLANAQIAVGSAAATAAASS---ATYGFTIGANGE-RIETTNTTNTTQGKWQGSTLEL 2944
+LAN+ + + TA + + G + +NGE + N +N+ G+W L L
Sbjct 907 ADSLANSGAIQAADSLTARLTGELVSAAGSKVTSNGEMALSALNLSNS--GQWIAKNLTL 964
Query 2945 NNLTLKSENQDVNVQGSRLTATGTTSFDGTKDLNVTAGTEHSQQETSSKTNSQSVSYTYG 3004
+L S V LT T + + L ++AG + S TN + G
Sbjct 965 KANSLTSAGDITGVDALTLTVNQTLNNHASGKL-LSAGV--LTLKADSVTNDGQLQ---G 1018
Query 3005 GGGSASIGKQTSTSESKSLTYVNSEVTLNKTEGRLNSLNIKGGEVSIQDRGNLQVNNIHV 3064
+ + G+ T+ + T +TL + G +N + G V + R L V+
Sbjct 1019 NATTITAGQLTNGGHLQGET-----LTLTASGG----VNNRSGGV-LMSRNALNVS---- 1064
Query 3065 ESLQDTASSSNSSRGGSIGGGYGSGSKNITASYNQSKGSSDSAWVNTTSKLL-IGNAQND 3123
TA+ SN G+I GG G N K S S T L G+
Sbjct 1065 -----TATLSNQ---GTIQGGGGVSLNATDRLQNDGKILSGSNLTLTAQVLANTGSGLVQ 1116
Query 3124 ANLDAMGVKNITNIGGVIANANKNADGSLTDHKNLNYTGNLELKDLQDHNNNNSSGFNVS 3183
A + V N N G V+A + + G+ LN TG L+ DL + + S N
Sbjct 1117 AATLLLDVVNTVNGGRVLATGSADVKGT-----TLNNTGTLQGADLLVNYHTFS---NSG 1168
Query 3184 TNIGIPQGGSKAASTAPKGS 3203
T +G G K +S G+
Sbjct 1169 TLLGTSGLGVKGSSLLQNGT 1188
Score = 58.9 bits (141), Expect = 2e-10
Identities = 175/819 (21%), Positives = 301/819 (37%), Gaps = 108/819 (13%)
Query 520 LNNDQGAIVAQGGIDLES-------NNGLDNQGGQLNLGRVKIQGERFNNDQGQLTVKQA 572
+ N G+I AQ + L+S N GL N GG LNL + G + G+
Sbjct 1852 ITNSGGSINAQNDLLLDSTGSIDNLNAGLINAGGALNLKAIGDIGNISSVISGKTV--SL 1909
Query 573 EIQTNSLSN--QSGQLISNQKLNIQTQTANNQKGKIQSVDQLDLNVANGLNNIEGQIASG 630
E T ++SN ++ Q N N + T +++ D L + A ++ +++G
Sbjct 1910 ESATGNISNLTRTEQWAMNNGYNHFSGTDTGPLAAVRATDSLFMGAAGDISITGAAVSAG 1969
Query 631 QQLNIQADQVNNQSGLIYSEQQ---GIELKANHAINNTSGIIQAKTQLNLASTQLDNTSG 687
+ + A N + + E++ G HA+ T + + + A +++ +
Sbjct 1970 DSVLLSAGNDLNMNAIQAGERRRYGGSGWYETHAVAPT--VTAGNSLMLSAGRDVNSQAA 2027
Query 688 HIQAENIQ--QQHTTVNNTQGSIVAGQSLISTVDQFDNHQGLIDAKNIQLTHQVLNNSGS 745
I AEN + VN S G D + + + D+ Q T +
Sbjct 2028 GIMAENSMDIRAGRDVNMAAESTGTGDH-----DSTFSMKTVHDSVRQQGTDMTSGGDIT 2082
Query 746 IYADQNIKITGQHILNTGSIA--AGQNIQLNTAKLQ----HEQAALIAAGLDRQGKLTST 799
+ A ++I + G I AG +I L TA E L Q T T
Sbjct 2083 VTAGRDITSVATAVTAKGDIRVNAGHDIVLGTATESDYHYSESGETRNRLLSHQTTRTIT 2142
Query 800 GDLDITAEQTTLHGQSF---AGQQLKVASKQQIDATNGQLQAKN-ID-LASDAGDISTRA 854
D + + L G AG L V + + L A N +D LA+ + D S R
Sbjct 2143 EDSVTREKGSLLSGNRVTVDAGDNLTVEGSDVVADRDVSLAAGNHVDVLAATSTDTSWRF 2202
Query 855 ATVIAEQL------------SLKSHDLIDNQQGTLSAQQLNLTANRLDNTQGHILHTGQD 902
L S +HD + GT +Q +A+ + +T G++ T
Sbjct 2203 KETKKSGLMGTGGIGFTIGSSKTTHD--RREAGTTQSQ----SASTIGSTAGNVSITAGK 2256
Query 903 QLDLNFSQSLNNQLGEIRSNAAELNIKTALLNNTEGQVVHAGTQQLNIQTAQLNGHLGHI 962
Q ++ S + N+ I ++ ++ + V Q+ + T L+G +G
Sbjct 2257 QAHISGSDVIANRDISITGDSVVVD-----PGHDRRTVDEKFEQKKSGLTVALSGTVGSA 2311
Query 963 LSNGTLQLKAGTLDVSGGVTSADQITIQA-NVLNNAQGQLIQRGTSNPLNLTIQQQLNNQ 1021
++N + T + S A Q T A + + Q + T +P + L Q
Sbjct 2312 INNAVTSAQE-TKESSDSRLKALQATKTALSGVQAGQAAAMATATGDPNATGVSLSLTTQ 2370
Query 1022 AGLIQSATATDIKAGSLNNQRGTLSSAQGQNLDVDVAGKLDNSQSGQI-YAGNQAHLQVG 1080
Q + +D +GS N G NL V GK G I AG+Q L+ G
Sbjct 2371 KSKSQQHSESDTVSGSTLN--------AGNNLSVVATGKNRGDNRGDIVIAGSQ--LKAG 2420
Query 1081 ---SIDNSHQGQINAQQNLQLTSQQQINNQSG--------------QIVANGDVQIQSQG 1123
S+D ++ ++ N Q T+ + ++ G + A+ + S+
Sbjct 2421 GNTSLDAANDVLLSGAANTQKTTGRNSSSGGGVGVSIGAGGNGAGISVFASVNAAKGSEK 2480
Query 1124 LNNSHGQMGSLQGG--LSLNTGSDTLINQSG------LIQAKKDIGIQAQ----RIDNQQ 1171
N + ++ G +++N+G DT++N + + D+ I +Q + D++Q
Sbjct 2481 GNGTEWTETTIDSGKTVTINSGRDTVLNGAQVNGNRIIADVGHDLLISSQQDTSKYDSKQ 2540
Query 1172 GQITTQGQAELISQAEIDNLEGAIAADLD-VNIRSQGLNNNKGQISSAQGNLTLNAGNGT 1230
+ G S G IAA D + R + G + G + G T
Sbjct 2541 TSVAAGGSFTFGSMTG----SGYIAASRDKMKSRFDSVAEQTGMF-AGDGGFDITVGRHT 2595
Query 1231 LTNQAATIVSGKTLTLSANQLDNSNHGQINSQNNADISI 1269
+ A V T T N LD G + N AD +
Sbjct 2596 QLDGA---VIASTATPDKNHLDTGTLGFSDLHNEADYKV 2631
Score = 46.2 bits (108), Expect = 1e-06
Identities = 138/691 (20%), Positives = 262/691 (38%), Gaps = 86/691 (12%)
Query 330 GVGVRNAGSMNSTQSTLTLNANGDLTNTGNLIANQGQLQLNAENIKNTGNISSATS--QV 387
G + N+G + Q+ L L++ G + N + N G LN + I + GNISS S V
Sbjct 1849 GGNITNSGGSINAQNDLLLDSTGSIDNLNAGLINAGG-ALNLKAIGDIGNISSVISGKTV 1907
Query 388 SLHSQNLDNSGLISSADELNIQQQGHVG--NRGTLNAARIVVDAGSLANSGSIEQTGAQA 445
SL S + S L + H + G L A R D+ + +G I TGA
Sbjct 1908 SLESATGNISNLTRTEQWAMNNGYNHFSGTDTGPLAAVR-ATDSLFMGAAGDISITGAAV 1966
Query 446 L----------------DLKAGSMSNIGGK-----IGIAKTSSTGGN-----GSESGGGS 479
++AG GG +A T + G + G + +
Sbjct 1967 SAGDSVLLSAGNDLNMNAIQAGERRRYGGSGWYETHAVAPTVTAGNSLMLSAGRDVNSQA 2026
Query 480 QPVEPNNAAQDGGSLEV-VNTDSTPTTPKTYETGYIHVRDQLNNDQGAIVAQGGIDLESN 538
+ N+ +V + +ST T V D + QG + GG D+
Sbjct 2027 AGIMAENSMDIRAGRDVNMAAESTGTGDHDSTFSMKTVHDSV-RQQGTDMTSGG-DITVT 2084
Query 539 NGLD----------------NQGGQLNLGRVKIQGERFNNDQGQLTVKQAEIQT------ 576
G D N G + LG + + ++ G+ + QT
Sbjct 2085 AGRDITSVATAVTAKGDIRVNAGHDIVLG-TATESDYHYSESGETRNRLLSHQTTRTITE 2143
Query 577 NSLSNQSGQLISNQKLNIQTQTANNQKGKIQSVDQLDLNVANGLNNIEGQIASGQQLNIQ 636
+S++ + G L+S ++ + +G D+ D+++A G N+++ A+ + +
Sbjct 2144 DSVTREKGSLLSGNRVTVDAGDNLTVEGSDVVADR-DVSLAAG-NHVDVLAATSTDTSWR 2201
Query 637 ADQVNNQSGLIYSEQQGIELKANHAINNTSGIIQAKTQLNLASTQLDNTSGHIQAENIQQ 696
+ +SGL+ + G + ++ ++ +A T + +++ + +T+G++ +Q
Sbjct 2202 FKE-TKKSGLMGTGGIGFTIGSSKTTHDRR---EAGTTQSQSASTIGSTAGNVSITAGKQ 2257
Query 697 QH---TTVNNTQGSIVAGQSLISTVDQFDNHQGLIDAKNIQLTHQVLNNSGSIYADQNIK 753
H + V + + G S++ VD + + + + + + + SG++ + N
Sbjct 2258 AHISGSDVIANRDISITGDSVV--VDPGHDRRTVDEKFEQKKSGLTVALSGTVGSAINNA 2315
Query 754 ITGQHILNTGSIAAGQNIQLNTAKLQHEQAALIAAGLDRQGKLTSTGDLDITAEQTTLHG 813
+T S + + +Q L QA AA T+TGD + T +L
Sbjct 2316 VTSAQETKESSDSRLKALQATKTALSGVQAGQAAA------MATATGDPNATGVSLSLTT 2369
Query 814 QSFAGQQLKVASKQQIDATNGQLQAKNIDLASDAGDISTRAATVIA-EQLSLKSHDLIDN 872
Q QQ + N + + GD R VIA QL + +D
Sbjct 2370 QKSKSQQHSESDTVSGSTLNAGNNLSVVATGKNRGD--NRGDIVIAGSQLKAGGNTSLDA 2427
Query 873 QQGTL--SAQQLNLTANRLDNTQGHI---LHTGQDQLDLNFSQSLNNQLGEIRSNAAELN 927
L A T R ++ G + + G + ++ S+N G + N E
Sbjct 2428 ANDVLLSGAANTQKTTGRNSSSGGGVGVSIGAGGNGAGISVFASVNAAKGSEKGNGTEWT 2487
Query 928 IKTALLNNTEGQVVHAGTQQLNIQTAQLNGH 958
T +++ + +++G + + AQ+NG+
Sbjct 2488 ETT--IDSGKTVTINSGRDTV-LNGAQVNGN 2515
Score = 45.1 bits (105), Expect = 3e-06
Identities = 102/543 (19%), Positives = 196/543 (36%), Gaps = 57/543 (10%)
Query 333 VRNAGSMNSTQSTLTLNANGDLTNTGNLIANQGQLQLNAENIKNTGNISSATSQVSLHSQ 392
VR G+ ++ +T+ A D+T+ + +G +++NA + G + + S +
Sbjct 2068 VRQQGTDMTSGGDITVTAGRDITSVATAVTAKGDIRVNAGHDIVLGTATESDYHYSESGE 2127
Query 393 NLDNSGLISSADELNIQQQGHVGNRGT-LNAARIVVDAG-SLANSGS-------IEQTGA 443
+ L+S I + +G+ L+ R+ VDAG +L GS +
Sbjct 2128 T--RNRLLSHQTTRTITEDSVTREKGSLLSGNRVTVDAGDNLTVEGSDVVADRDVSLAAG 2185
Query 444 QALDLKAGSMSNIGGKIGIAKTSSTGGNGSESGGGSQPVEPNNAAQDGGSLEVVNTDSTP 503
+D+ A + ++ + K S G +GG + + D + S
Sbjct 2186 NHVDVLAATSTDTSWRFKETKKSGLMG----TGGIGFTIGSSKTTHDRREAGTTQSQSAS 2241
Query 504 TTPKTYETGYIHVRDQLNNDQGAIVAQGGIDLESNNGLDNQGGQLNLGRVKIQGERFNND 563
T T I Q + ++A I + ++ + + G + E+F
Sbjct 2242 TIGSTAGNVSITAGKQAHISGSDVIANRDISITGDSVVVDPGHDR-----RTVDEKFEQK 2296
Query 564 QGQLTVKQAEIQTNSLSN-----QSGQLISNQKLNIQTQTANNQKGKIQSVDQLDLNVAN 618
+ LTV + ++++N Q + S+ +L T G +Q+ + A
Sbjct 2297 KSGLTVALSGTVGSAINNAVTSAQETKESSDSRLKALQATKTALSG-VQAGQAAAMATAT 2355
Query 619 GLNNIEGQIASGQQLNIQADQVNNQSGLIYSEQQGIELKANHAI----------NNTSGI 668
G N A+G L++ + +Q G L A + + +N I
Sbjct 2356 GDPN-----ATGVSLSLTTQKSKSQQHSESDTVSGSTLNAGNNLSVVATGKNRGDNRGDI 2410
Query 669 IQAKTQLNL-ASTQLDNTSGHIQAENIQQQHTTVNNTQGSIVAGQSL--------ISTVD 719
+ A +QL +T LD + + + Q TT N+ G S+ IS
Sbjct 2411 VIAGSQLKAGGNTSLDAANDVLLSGAANTQKTTGRNSSSGGGVGVSIGAGGNGAGISVFA 2470
Query 720 QFDNHQGLIDAKNIQLTHQVLN-------NSGSIYADQNIKITGQHILNTGSIAAGQNIQ 772
+ +G + T ++ NSG ++ G I+ + Q
Sbjct 2471 SVNAAKGSEKGNGTEWTETTIDSGKTVTINSGRDTVLNGAQVNGNRIIADVGHDLLISSQ 2530
Query 773 LNTAKLQHEQAALIAAGLDRQGKLTSTGDLDITAEQTTLHGQSFAGQQLKVASKQQIDAT 832
+T+K +Q ++ A G G +T +G + + ++ S A Q A D T
Sbjct 2531 QDTSKYDSKQTSVAAGGSFTFGSMTGSGYIAASRDKMKSRFDSVAEQTGMFAGDGGFDIT 2590
Query 833 NGQ 835
G+
Sbjct 2591 VGR 2593
Score = 42.0 bits (97), Expect = 3e-05
Identities = 147/730 (20%), Positives = 274/730 (38%), Gaps = 95/730 (13%)
Query 353 DLTNTGNLIANQGQLQLNAENIKNTGNISSATSQVSLHSQ-NLDN--SGLISSADELNIQ 409
D+T + + +QL NI N+G +A + + L S ++DN +GLI++ LN++
Sbjct 1831 DITLHNGSVISGNNVQLAGGNITNSGGSINAQNDLLLDSTGSIDNLNAGLINAGGALNLK 1890
Query 410 QQGHVGNRGTLNAARIVVDAGSLANSGSIEQTGAQALD--------LKAGSMSNI----- 456
G +GN ++ + + V + N ++ +T A++ G ++ +
Sbjct 1891 AIGDIGNISSVISGKTVSLESATGNISNLTRTEQWAMNNGYNHFSGTDTGPLAAVRATDS 1950
Query 457 -----GGKIGIAKTSSTGGNGSESGGGS----QPVEPNNAAQDGGSLEVVNTDSTPTTPK 507
G I I + + G+ G+ ++ + GGS T + T
Sbjct 1951 LFMGAAGDISITGAAVSAGDSVLLSAGNDLNMNAIQAGERRRYGGS-GWYETHAVAPTVT 2009
Query 508 TYETGYIHVRDQLNNDQGAIVAQGGIDLESNNGLDNQGGQLNLGRVKIQGERFNNDQGQL 567
+ + +N+ I+A+ +D+ + G +N+ ++
Sbjct 2010 AGNSLMLSAGRDVNSQAAGIMAENSMDIRA-------GRDVNMAAESTGTGDHDSTFSMK 2062
Query 568 TVKQAEIQTNSLSNQSGQLISNQKLNI-QTQTANNQKGKIQSVDQLDLNVANGLNNIEGQ 626
TV + Q + G + +I TA KG I+ D+ + +
Sbjct 2063 TVHDSVRQQGTDMTSGGDITVTAGRDITSVATAVTAKGDIRVNAGHDIVLGTATESDYHY 2122
Query 627 IASGQQLN----------IQADQVNNQSGLIYSEQQGIELKANHAINNTSGIIQAKTQLN 676
SG+ N I D V + G + S + + + A + + A ++
Sbjct 2123 SESGETRNRLLSHQTTRTITEDSVTREKGSLLSGNR-VTVDAGDNLTVEGSDVVADRDVS 2181
Query 677 LAS-TQLDNTSGHIQAENIQQQHTTVNNTQGSIVAGQSLISTVDQFDNHQGLI------- 728
LA+ +D + + + + T + G+ G ++ S+ D +
Sbjct 2182 LAAGNHVDVLAATSTDTSWRFKETKKSGLMGTGGIGFTIGSSKTTHDRREAGTTQSQSAS 2241
Query 729 ----DAKNIQLT--HQVLNNSGSIYADQNIKITGQHILNTGSIAAGQNIQLNTAKLQHEQ 782
A N+ +T Q + + A+++I ITG ++ + G + + K + ++
Sbjct 2242 TIGSTAGNVSITAGKQAHISGSDVIANRDISITGDSVV----VDPGHDRRTVDEKFEQKK 2297
Query 783 AALIAAGLDRQGKLTSTGDLDITAEQTTLHGQSFAGQQLKVASKQQIDATNGQLQAKNID 842
+ L A G + S + +T+ Q T + L+ GQ A
Sbjct 2298 SGLTVA---LSGTVGSAINNAVTSAQETKESSDSRLKALQATKTALSGVQAGQAAA---- 2350
Query 843 LASDAGDISTRAATVIAEQLSLKS--HDLIDNQQG-TLSA-QQLNLTA---NRLDNTQGH 895
+A+ GD + ++ KS H D G TL+A L++ A NR DN +G
Sbjct 2351 MATATGDPNATGVSLSLTTQKSKSQQHSESDTVSGSTLNAGNNLSVVATGKNRGDN-RGD 2409
Query 896 ILHTGQDQLDLNFSQSLNNQLGEIRSNAAELNIKTALLNNTEGQV---VHAGTQQLNIQT 952
I+ G QL + SL+ + S AA T +++ G V + AG I
Sbjct 2410 IVIAG-SQLKAGGNTSLDAANDVLLSGAANTQKTTGRNSSSGGGVGVSIGAGGNGAGISV 2468
Query 953 -AQLNGHLGHILSNGTLQLKAGTLDVSGGVTSADQITIQA---NVLNNAQ--GQLIQRGT 1006
A +N G NGT + T+D S +TI + VLN AQ G I
Sbjct 2469 FASVNAAKGSEKGNGT-EWTETTID------SGKTVTINSGRDTVLNGAQVNGNRIIADV 2521
Query 1007 SNPLNLTIQQ 1016
+ L ++ QQ
Sbjct 2522 GHDLLISSQQ 2531
Score = 40.8 bits (94), Expect = 6e-05
Identities = 265/1369 (19%), Positives = 467/1369 (34%), Gaps = 221/1369 (16%)
Query 1878 GQIKAGGHLDLNGAQVVNDKSQILAGGELKNEGGTIDSG-TQIAGIRKIVNTGTQVKYWK 1936
G + A ++ L K + +AG L G++++G T +AG V TGT
Sbjct 371 GTVNAAENVTLTTTDDTTLKGRSIAGKTLTVSSGSLNNGGTLVAGRDATVKTGTFSNTGT 430
Query 1937 YEGQW--------DNPFENSSETTFDLSISQALGNQNLNQNQLSTVAVSNNQ-------- 1980
+G + S +T D+S A + + + V VS
Sbjct 431 VQGNGLKVTATDLTSTGSIKSGSTLDISARNATLSGDAGAKDSARVTVSGTLENRGRLVS 490
Query 1981 ------SAEHIQNSQTTQQEINGLQTSNNNTQLNQTKDVDLDQLNLKDSQSQNAPQASAV 2034
SA I NS T + +++ T ++ L L + S A + SA
Sbjct 491 DDVLTLSATQINNSGTLSGAKELVASADTLTTTEKSVTHSDGNLMLNSASSTLAGETSAG 550
Query 2035 ETVQQQSATSAPSSTPQGTSEEIRSIDFSNIKVPNSA----LYKVNADSKAGYLIETD-P 2089
TV + + ++T Q + S+D N ++ + + +NA K + ++ P
Sbjct 551 STVSVKGNSLKTTATAQTQGNSV-SVDVQNAQLDGTQAARDILTLNASEKLTHSGKSSAP 609
Query 2090 AFADYKKWLSSDYMLDALGLDPALQQKRLGDGFYEQRLVQDQIANLTGYRFLEGFANDDE 2149
+ + L+S +L L+ Q L+Q + + + L+ N
Sbjct 610 SLSLSAPELTSSGVLVGSALNTQSQT------LTNSGLLQGKASLTVNTQRLDNQQNGTL 663
Query 2150 QYKALMNNGITFAKLYGLRPGIALTAAQTAQLTSDIVWLVEQSVTLPDGTITKALVPQVY 2209
A + I + GL G TA L++ P I L
Sbjct 664 YSAADLTLDIPDIRNSGLITGDNGLTLNTASLSN------------PGKIIADTL----- 706
Query 2210 VKVRVGDLKGDGTLLSGNSVNLKLDGDLINGATIAGREALQITADNVQ------NLNGRI 2263
VR L GDG L + L L GD ++ GR +TA ++ + G
Sbjct 707 -NVRATTLDGDGLLQGAGA--LALAGDTLS----QGRNGRWLTAGDLSLRGKTLHTAGTT 759
Query 2264 QGNQVAIETQKDLNNIGGQIIAKDAMALKVGGNLNIESTTRTSESKVGNFSSSITNVDRV 2323
QG + ++ N+ G ++A + G L T+ G+ + + D
Sbjct 760 QGQNLTVQADNWANS--GSVLATGNLTASATGQL----TSTGDIMSQGDTTLNAATTDNR 813
Query 2324 AGLYVGNGSTKQLDPNQATLMLNVAGNS-SLKGVQINNSNSATVLNTTGNVDLGTVSVGK 2382
L + T LD N V G+ +++ + NS + T + + L V
Sbjct 814 GSLL--SAGTLSLDGNSLDNRGTVQGDHVTIRQNSVTNSGTFTGIAA---LTLAARMVSP 868
Query 2383 QETLKIDDKNGYQLKQQQDVGSQIKSAGSLLINGQNITSKA----------VDLNSQQGD 2432
Q L + G + ++G L I +ITS D + G
Sbjct 869 QPAL-------------MNNGGSLLTSGDLTITAGSITSSGHWQGKRVLITADSLANSGA 915
Query 2433 IQ----LSAQKDIVLDNGLNQSTVSSQSQSKGSFGGKKSSTYDASSSTSIANQLNAGQNI 2488
IQ L+A+ L + S+ + + S + A + T AN L + +I
Sbjct 916 IQAADSLTARLTGELVSAAGSKVTSNGEMALSALNLSNSGQWIAKNLTLKANSLTSAGDI 975
Query 2489 -------------IINSAQGNI-SATHLQAEAGNNIQIHAQQGNVTLLSAID----DKRE 2530
+ N A G + SA L +A + QGN T ++A +
Sbjct 976 TGVDALTLTVNQTLNNHASGKLLSAGVLTLKADSVTNDGQLQGNATTITAGQLTNGGHLQ 1035
Query 2531 SSTSSKKGVATYNNRQSGYIDQEVA----------QTTLKAGDTVDINAAKNIELQANDV 2580
T + NNR G + A Q T++ G V +NA ++ +
Sbjct 1036 GETLTLTASGGVNNRSGGVLMSRNALNVSTATLSNQGTIQGGGGVSLNATDRLQNDGK-I 1094
Query 2581 QAGNSIYVGNTLMQRQADGSLKAADGSLMPENVTLS--TLATKDEQWDEQQKGYRGIVKD 2638
+G+++ + ++ G ++AA L N LAT
Sbjct 1095 LSGSNLTLTAQVLANTGSGLVQAATLLLDVVNTVNGGRVLATGSAD-------------- 1140
Query 2639 IVKATAVGLAGIEALAPGLKAPKITVSESTGKRTEQISQTGSSLKADNV-YVGSSGQTTL 2697
VK T + G A L + T T + GSSL + + S+G L
Sbjct 1141 -VKGTTLNNTGTLQGADLLVNYHTFSNSGTLLGTSGLGVKGSSLLQNGTGRLYSAGNLLL 1199
Query 2698 TSTDITAKNTILLGQKVTLNAAEEQKITVESTSKETVQGLGAKLN---KDSIRLGGFVLE 2754
+ D + + ++ VTL K+ T+ T+ G L+ +++I GG +
Sbjct 1200 DAQDFSGQGQVVATGDVTL------KLIAALTNHGTLAA-GKTLSVTSQNAITNGGVMQG 1252
Query 2755 DASQSSKTTETTHKLGSINTENLKIQGVEGVDILGQNITATGDTLIDHGRGDLNVGGYEN 2814
DA G T N + +G N + L + G L GG +
Sbjct 1253 DAMVLGA--------GEAFTNNGMLTAGKG------NSVFSAQRLFLNAPGSLQAGGDVS 1298
Query 2815 KTTVEDKTHVETISTEVGVRNAYLDAALALGAVKDAAEAVKQAKDQYSQAQRDYASGK-- 2872
+ D T + + G + L A+ A +K D+ D +G
Sbjct 1299 LNSRSDIT-ISGFTGTAGSLTMNVAGTLLNSALIYAGNNLKLFTDRLHNQHGDILAGNSL 1357
Query 2873 -ITKEA--------------LDDSKANVAMATANLANAQIAVGSAAATAAASSATYGFTI 2917
+ K++ ++ ++ ++ M TA+L N+ A+ ++ SS +
Sbjct 1358 WVQKDSSGTANSEIINRSGNIETTRGDITMNTAHLLNSWDAISASHEVIPGSSHGVISPV 1417
Query 2918 GANGE--RIETTNTTNTTQGKW-QGSTLELNNLTLKSENQDVNVQGSRLTATGTTSFDGT 2974
N + + W +G+T+ + + V V S A G
Sbjct 1418 PENNRWWGVVRHDGVEYLAVYWGEGATVPDEYRIRTGDTETVTVSASGHAAR----ISGG 1473
Query 2975 KDLNVTAGTEHSQQETSSKTNSQSVS--------YTYGGGGSASIGKQTSTSESKSLTY- 3025
D+++ AG ++ S ++S + G G ++ + S S K+
Sbjct 1474 ADMHIRAGRLDNEASFILAGGSMTLSGDTLNNQGWQEGTTGKETVWRLASGSLPKAWFTE 1533
Query 3026 ----VNSEVTLNKTEGRLNSLNIKGGEVSIQDRGNLQV-NNIHVESLQDTASSSNSSRGG 3080
V +V+ + TE G + Q R + +++ DT +++ R G
Sbjct 1534 PWYKVYRQVSTDATEA-------SGTSPAGQYRAVISAASDVSASFATDTGNTTVMPRAG 1586
Query 3081 SIGGGYGSGSKNITASYNQSKGSSDSAWVNTTSKLLIGNAQNDANLDAM 3129
G S N S+G S A +N + + G NDA D +
Sbjct 1587 GAGNTITVPSLNSLTPPTVSQGVSGEALLNESGTGITGPVWNDALPDTL 1635
Score = 38.5 bits (88), Expect = 3e-04
Identities = 126/564 (22%), Positives = 203/564 (36%), Gaps = 88/564 (16%)
Query 47 SDSDSMGFDSSHLKKLKQLN-FAVISVLGASIFTLPLNTIA-DSQIIADKGAPTSQQPTI 104
S D G D+ L + LN A +L A + TL +++ D Q+ + T+ Q T
Sbjct 971 SAGDITGVDALTLTVNQTLNNHASGKLLSAGVLTLKADSVTNDGQLQGNATTITAGQLTN 1030
Query 105 LNSSNGVTQVNIQTPSAGGVSRNTYSQFDVGQEGAIL--NNARNNTQTQLG--GWIQGNP 160
G T + ++GGV+ + G +L NA N + L G IQG
Sbjct 1031 GGHLQGET---LTLTASGGVNNRS---------GGVLMSRNALNVSTATLSNQGTIQGGG 1078
Query 161 WLAKGEAKVILNEVNSSNPSQLKGYIEVAGKQAQVVIANPSGLVCDGCGVINADRFTLT- 219
++ + N+ + S L +V ++ + L+ D +N R T
Sbjct 1079 GVSLNATDRLQNDGKILSGSNLTLTAQVLANTGSGLV-QAATLLLDVVNTVNGGRVLATG 1137
Query 220 ----TGQAVMNQGYLESFRVREGQITIQGKGLNGSLTPFTDVYARALQVNAGLYAKELNV 275
G + N G L+ + T G + + LQ G N+
Sbjct 1138 SADVKGTTLNNTGTLQGADLLVNYHTFSNSGTLLGTSGLGVKGSSLLQNGTGRLYSAGNL 1197
Query 276 VLGQNDIN-------VNDPTTSNVSPIQSN-TSANNKPQFALDVGQL--GGMYAGKIFLV 325
+L D + D T ++ + ++ T A K + GG+ G ++
Sbjct 1198 LLDAQDFSGQGQVVATGDVTLKLIAALTNHGTLAAGKTLSVTSQNAITNGGVMQGDAMVL 1257
Query 326 GTEQGV---GVRNAGSMNSTQST--LTLNANGDLTNTGNLIANQGQLQLNAENIKNTGNI 380
G + G+ AG NS S L LNA G L G++ N + +I +G
Sbjct 1258 GAGEAFTNNGMLTAGKGNSVFSAQRLFLNAPGSLQAGGDVSLN------SRSDITISGFT 1311
Query 381 SSATSQVSLHSQNLDNSGLISSADELNIQQQGHVGNRGTL---NAARIVVDAGSLANS-- 435
+A S + L NS LI + + L + G + N+ + D+ ANS
Sbjct 1312 GTAGSLTMNVAGTLLNSALIYAGNNLKLFTDRLHNQHGDILAGNSLWVQKDSSGTANSEI 1371
Query 436 ----GSIEQTGAQALDLKAGSMSNIGGKIGIAKTSSTGGNGSESGGGSQPVEPNN----- 486
G+IE T + + + N I + G S G PV NN
Sbjct 1372 INRSGNIETTRGD-ITMNTAHLLNSWDAISASHEVIPGS----SHGVISPVPENNRWWGV 1426
Query 487 AAQDGGSLEVVNTDSTPTTPKTYE-------------TGY---------IHVR-DQLNND 523
DG V T P Y +G+ +H+R +L+N+
Sbjct 1427 VRHDGVEYLAVYWGEGATVPDEYRIRTGDTETVTVSASGHAARISGGADMHIRAGRLDNE 1486
Query 524 QGAIVAQGGIDLESNNGLDNQGGQ 547
I+A G + L S + L+NQG Q
Sbjct 1487 ASFILAGGSMTL-SGDTLNNQGWQ 1509
Score = 36.2 bits (82), Expect = 0.001
Identities = 110/490 (22%), Positives = 174/490 (36%), Gaps = 57/490 (12%)
Query 2900 GSAAATAAASSATYGFTIGANGERIETTNTTNTTQGKWQGSTLELNNLTLKSENQDVN-- 2957
G AA A+ YG T G I T + T TT + L L + + +N
Sbjct 130 GKAANVMVANP--YGITCDGCGF-INTPHATLTTGRPVMNADGSLQALEVTEGSITINGA 186
Query 2958 -VQGSR-------LTATGTTSFDGTKDLNVTAGTEHSQQETSSKTNSQSVSYTYGGGGSA 3009
+ G+R AT + KDL VTAG T VS G G
Sbjct 187 GLDGTRSDAVSIIARATEVNAALHAKDLTVTAGANRI-------TADGRVSALKGEGDVP 239
Query 3010 SIGKQTSTSESKSLTYVNSEVTLNKTEGRLNSLNIKGGEVSIQDRGNLQVNNIHVESLQD 3069
+ T ++ T + L +L + G++ + G L + N
Sbjct 240 KVAVDTGALGGMYARRIHLTSTESGVGVNLGNLYAREGDIILNSAGKLVLKNSLAGGNTT 299
Query 3070 TASSSNSSRGGSIGGGYGSGSKNITASYNQSKGSSDSAWVNTTSKLLIGN-AQNDANLDA 3128
+ S G + GG S + + NQS+ +D V ++S ++ N + A +A
Sbjct 300 VTGTDVSLSGDNKAGGNLSVTGTTGLTLNQSRLVTDKNLVLSSSGQIVQNGGELTAGQNA 359
Query 3129 M-GVKNITNIGGVIANANKNADGSLTDHKNLNYTGNLELKDLQDHNNNNSSGFNVS---- 3183
M +++ G + NA +N + TD L + N+ G V+
Sbjct 360 MLSAQHLNQTSGTV-NAAENVTLTTTDDTTLKGRSIAGKTLTVSSGSLNNGGTLVAGRDA 418
Query 3184 -------TNIGIPQG-GSKAASTAPKGSTTIGLNSSGQETE-QLTKATLG--QGSVTNAT 3232
+N G QG G K +T T+ G SG + ATL G+ +A
Sbjct 419 TVKTGTFSNTGTVQGNGLKVTAT---DLTSTGSIKSGSTLDISARNATLSGDAGAKDSAR 475
Query 3233 ADTNRDINNTQEITRDQTTGMLNGSVTVDHRLLSESGRAEIVKEQEQLIENFRQSAENLA 3292
+ + N + D +L S T + + SG E+V SA+ L
Sbjct 476 VTVSGTLENRGRLVSDD---VLTLSATQINNSGTLSGAKELV-----------ASADTLT 521
Query 3293 KALPDGVYKDKALQTLNDVQAKLYNLPSEYKEVGVVGNSVASELLKRGM-ESQDVEALFS 3351
+ D L LN + L S V V GNS+ + + S V+ +
Sbjct 522 TTEKSVTHSDGNLM-LNSASSTLAGETSAGSTVSVKGNSLKTTATAQTQGNSVSVDVQNA 580
Query 3352 KLDFFYAAKE 3361
+LD AA++
Sbjct 581 QLDGTQAARD 590
Score = 24.6 bits (52), Expect = 4.4
Identities = 20/79 (25%), Positives = 31/79 (39%), Gaps = 2/79 (3%)
Query 3414 GMTILSNIADLGNSIKDISESTGVDIEKVQLAVGLLISGPVRLVIESGKSMAVDSVVGEK 3473
G I N+ NS+ + TGVD + + L +L+ ++ DSV +
Sbjct 955 GQWIAKNLTLKANSLTSAGDITGVDALTLTVNQTLNNHASGKLLSAGVLTLKADSVTNDG 1014
Query 3474 VAQG--VDILANSMTAAAH 3490
QG I A +T H
Sbjct 1015 QLQGNATTITAGQLTNGGH 1033
>E0SDG8 Deoxyribonuclease CdiA [Dickeya dadantii (strain 3937)]
Length=3326
Score = 268 bits (685), Expect = 7e-74
Identities = 637/2904 (22%), Positives = 1093/2904 (38%), Gaps = 484/2904 (17%)
Query 319 AGKIFLVGTEQGVGVRNAGSMNSTQSTLTLNANG-----DLTNTGNLIANQGQLQLNAEN 373
AG + G G+ Q +TL +G +L N G L A G + A
Sbjct 51 AGGVATAGALTAQGLALTAGRWRHQGAVTLGGDGRLVLDELDNGGTLRAG-GAWDMQAAA 109
Query 374 IKNTGNISS-----------------ATSQVSLHSQNLDNSGLISSADELNIQQQGHVGN 416
+ N G + A +V+L + +LDN G + D L + G N
Sbjct 110 LSNGGTLQGGRLALTLSGAAVNRGTLAGERVTLTADSLDNGGTLLGMDALTLAIAGTARN 169
Query 417 RGT---LNAARIVVDAGSLANSGSIEQTGAQALDLKAGSMSNIGGKIGI-AKTSSTGGNG 472
+ + L+ + AG+L N G Q +L + A + N G +G+ A T + G
Sbjct 170 QASGQWLSQGESRLTAGTLDNQG---QWQGDSLSVTADRIRNAGQLLGLSALTLTADGTL 226
Query 473 SESGGGSQPVE----------PNNAAQDGGSLEVVNTDSTPTTPKTYETGYIHVRDQ--- 519
+ + G+ + N+ G L + DS + G + V
Sbjct 227 TNTATGTLLTQGAAVLRAATVDNDGEWQAGRLRLT-ADSLRNGGRIQSDGALDVALSPAG 285
Query 520 LNNDQGAIVAQGGIDLESNNGLDNQGGQLNLGRVKIQGERFNNDQGQLTVKQAEIQTNSL 579
+ + G + A G L + GLDN+G G + + G +N GQL + A T S
Sbjct 286 VLTNTGTLAANGDTTL-TPGGLDNRGAVSVRGDLTVTGTDLDN-AGQLAARGALTLTGSY 343
Query 580 SNQSGQLISNQKLNIQTQTANNQKGK------------------IQSVDQLDLNVANGLN 621
+ +G L S+ L ++ T N G+ I +D L + L
Sbjct 344 AG-AGSLYSDAALTLRGTTLANDGGRWQGQTVDIGGGPLTNDGNITGLDSLTVTTTGALT 402
Query 622 NIEGQIASGQQLNIQADQVNNQSGLIYSEQQGIELKANHAINNTSGIIQAKTQLNLASTQ 681
N G++A GQ L I AD ++N L+ + + + A A N TSG
Sbjct 403 N-RGRLA-GQTLGITADALDNAGTLLGVDALTLAI-AGTARNQTSG------------QW 447
Query 682 LDNTSGHIQAENIQQQHTTVNNTQGSIVAGQSLISTVDQFDNHQGLIDAKNIQLT-HQVL 740
L N +G + A + N Q G SL +T D+ DN L+ + LT + L
Sbjct 448 LSNGAGRLTAGTLD------NRGQWQ---GDSLDATADRLDNAGTLLGLSAMTLTVNGAL 498
Query 741 NNSGSIYADQNIKITGQHILNTGSIAAGQNIQLNTAKLQHEQAALIAAGLDRQGKLTSTG 800
N+G +L G+ N + Q L A L G++ S G
Sbjct 499 TNTG-------------RLLTQGAAVLSAATADNDGEWQTGSLWLTADSLRNGGQIHSDG 545
Query 801 DLDIT---AEQTTLHGQSFAGQQLKVASKQQIDATN-GQLQAKNIDLASDAGDISTR--- 853
++ IT A+ L A +QL Q ++A G+L + A G I+ R
Sbjct 546 EVRITLPTADGDPLRPTLRAARQLA----QDVEAIGAGRLSNTGVLTAGGDGRITGRGLD 601
Query 854 -AATVIAE-QLSLKSHDLIDNQQGTLSAQQLNLTANRLDNTQGHILHTGQDQLDLNFSQS 911
A T+ A L+L + DL + G L ++ L+LT + LDN + G
Sbjct 602 NAGTLAAGGALTLAAGDLTN--AGRLESRTLSLTGDSLDNGGTLLAEQG----------- 648
Query 912 LNNQLGEIRSNAAELNIKTALLNNTEGQVVHAGTQQLNIQTAQLNGHLGHILSNGTLQLK 971
EL + L +G+++ G Q+ T G TL L
Sbjct 649 ------------GELTLGGGLHVGADGRLLSNGDWQVQAGTVTSLGQW----QGKTLLLS 692
Query 972 AGTLDVSGGVTSADQITIQAN--VLNNAQGQLIQRGTSNPLNLTIQQQLNNQAGLIQSAT 1029
A +LD G + + D +T+ A Q++ G T+ QQ G + A
Sbjct 693 AASLDNGGALLATDAVTLTLTQGYTGGAGSQVLGSGAVTLTADTVTQQ--GDIGGDRLAL 750
Query 1030 ATDIKAGSLNNQRGTLSSAQGQNLDVDVAGKLDNSQSGQIYAGNQAHLQVGSIDNSHQGQ 1089
T G+L N + +Q LDV G+L N +G + A + ++DN+ G
Sbjct 751 TT----GTLTNGGRLVGLSQ---LDVTSRGQLTNRATGSLLGNGTAGVTAATLDNA--GS 801
Query 1090 INAQQNLQLTSQQQINNQSGQIVANGDVQIQSQGLNNSHGQMGSLQGGLSLNTGSDTLIN 1149
+ A L LT+ N G +Q S N + G L+ G+ TL
Sbjct 802 VQAD-TLTLTADTVTNA--------GRMQGTSALTLNGVSRYTGTDGSQLLSGGTATLA- 851
Query 1150 QSGLIQAKKDIGI-QAQRIDNQQGQITTQGQAELISQAEIDNLEGAIAADLDVNIRSQGL 1208
I + G+ QA + + +T++GQ + +D A + + ++GL
Sbjct 852 ----IDNADNAGLWQAGELRFRGASLTSRGQITGLDSLTVD----AASLTSTGQLTTRGL 903
Query 1209 NNNKGQISSAQGNLTLNAG-----NGTLTNQAA-TIVSGKTLTLSANQLDNSNHGQINSQ 1262
+GQ G LT G + ++TNQ ++SG T +L+ L N Q
Sbjct 904 ATLRGQRFDNGGTLTALGGFTARFSDSVTNQGGGQLLSGGTGSLTTGTLVNRGRWQ---- 959
Query 1263 NNADISIVKDINNTSGVIAAKQQLILSSQGLNNTTGQIGTVQGNLHI------DAGSQLL 1316
+L L++ L N +G GN+ + +AGSQ+
Sbjct 960 --------------------SDRLTLTADTLRNPGTLLGLDDGNIQLTGAYVGEAGSQVG 999
Query 1317 NN-----------QQGRIQSGQDLNLNATGIDNTQGQISSKNQLQLDSREQLLNNRQGTL 1365
N Q G+ Q+ +D+ L AT + N QG I+ QL EQL N TL
Sbjct 1000 GNGALSLSAATIDQAGQWQA-RDVTLRATRLRN-QGSITGSGQLTATLDEQLENLAGATL 1057
Query 1366 -------------------SAENLTIDSGELNNDQGLIQAQQSIQIDTHQHNLSNTNSGA 1406
LT+ G L ++QG Q Q+ L+N
Sbjct 1058 LGGTVWLGGATVSNGGQIQGRSGLTVQGGTLLDNQGGGQLLSGGQLALGATQLTNAG-WV 1116
Query 1407 QGGILSQGNIQLNNIQTLDNQQGYL-----------ASAQQLDLQANQVFNQNGTLLAAK 1455
QG L+ QL+N TL Q G A QLD+ + + GTLL
Sbjct 1117 QGQDLTLTTAQLDNSGTLQAQSGLTLHLPQWTNRGTVQAGQLDITTDGALDNRGTLLGLT 1176
Query 1456 QLNLQGTGQNQLLNNQSGQMLSMGGMNLNIDQINNKGKANTADADSHIMAAGELNIT-TQ 1514
+L LQ N N ++ S GG+ L Q+ G+ A D T T
Sbjct 1177 RLALQAASLN---NADGARLYSAGGLQLRTGQLTQDGQL-AALGDLRADIGTPFTFTRTL 1232
Query 1515 QLDNQNTLNTDPANTSIQGIDANTLNVTSK-VLNNQSGVIRSSADQNLNVQQALNNQSGQ 1573
Q TL + + + VTS L Q ++ + L+ +SG
Sbjct 1233 AAGGQLTLAVTGDLVQAGTLQGHGVTVTSTGTLTQQGRIVAGGGNSTLSAAAISQTESGS 1292
Query 1574 ISSEKQLTLVGDQLEINNLNGQILAGTALDLIAQSLSGDGKLLSLGNAKLSLQNDYIHSS 1633
I L+L N+ + GTA DL+ Q+ G ++N +
Sbjct 1293 IQGGGPLSLRAT----GNIVNRGFVGTAGDLLVQA----------GGV---MENGSLLYG 1335
Query 1634 GAQLQANQDLSLSTKGNIINNGTINAGNQLALNAANITNQQAGKIESHDTRLTAQN-TLN 1692
G LQ ++ GNI+ G++ A NA++ +G IE+ +T + TL
Sbjct 1336 GGNLQLLSAALVNRFGNILAGGSLWIQRDAAGNASDSVLNSSGTIETQRGDITVRTGTLT 1395
Query 1693 NT--GLINGDFTRLQAETLNNQGTGRIYGTTLAIQA----------NTLNNQPDSTGTAP 1740
N GL+ + A+ + G IY + +T DS T
Sbjct 1396 NQREGLVVTESGSTAADMPDWVGGTTIYIPVERFEVIKDYLVYSFEHTPGAGSDSPTTYN 1455
Query 1741 VIASRGDLHLGVQTLNNLSNPTDYTSQ---ALIFSAGNLYLGAALDANDYATGQADVIHN 1797
H+ Q + S + S+ +LI SAG++ + +++ ND A +I +
Sbjct 1456 YFYPFPLSHVSKQEFSASSKIVNIESKGGSSLIHSAGDINIFSSVLVND-----ASIIAS 1510
Query 1798 ESATIESLGDMNLSAKQINNINK----------------YFKTEQVEVSRKDGLEKYCDA 1841
E + + G + S+ Q +++ Y + + R++G+ Y D
Sbjct 1511 EKNILMNGGVLKNSSYQSGVMSESLIYEYERDDKDDFLPYIEWLWEKTKREEGVSDY-DY 1569
Query 1842 WCTFDGNYYDGNPYE------DWMRYYYSEITYETRTTESAPGQIKAGGHLDLNGAQVVN 1895
W G Y+ + Y D +Y + ++ I+AGG + N +Q ++
Sbjct 1570 WEYLSG--YNIHAYNRNILTNDRFKYVLKDRQIIFTPGQTYAATIQAGGAITANFSQNIS 1627
Query 1896 DKSQILAGGELKNEGGTIDSGTQIAGIRKIVNTGTQVKYWKYEGQWDNPFENS-SETTFD 1954
+ + G T +AG+ + G Q G N ++ S
Sbjct 1628 NTNLQPGSGGFMPAMAT----PTLAGVNALGPVGAQADRGLNGGTAGNVSGSTLSGAGNG 1683
Query 1955 LSISQALGNQNLNQNQLSTVAVSNNQSAEHIQNSQTTQQEINGLQTSNNNTQLNQTKDVD 2014
++++ G N + ++ +++ SA + G + + V
Sbjct 1684 VALAGQAGRLNAGYSAVTRDNTASSGSALNPVGIPAGPGTAGGAPVAGASLT-----PVA 1738
Query 2015 LDQLNLKDSQSQNAPQASAVETVQQQSATSAPSSTPQG------TSEEIRSI-----DFS 2063
L L D Q A A ++ + S T P T Q T+ + R + S
Sbjct 1739 PGALALSDLQ---AALAQGLQQLGSPSLTDYPLPTSQSGLFVADTAGDSRYLIRTNPTLS 1795
Query 2064 NIKVPNSALYK-----VNADSKAGYLIETDPAFADYKKWLSSDYMLDALGLDPALQQKRL 2118
+ ++AL+ + +E P D + L S Y+L L LD + L
Sbjct 1796 QLGQVDNALFGDLRGLLGQTPGTTAPVERSPTLTDPTQVLGSSYLLGKLNLDAEHDYRFL 1855
Query 2119 GDGFYEQRLVQDQIANLTGYRFLEGFANDDEQYKALMNNGITFAKLYGLRPGIALTAAQT 2178
GD ++ R + + + + TG R+L G ++ Q + LM+N L+ G++LT Q
Sbjct 1856 GDAAFDTRYISNAVLSQTGQRYLNGVGSELAQMQQLMDNAAAEKSRLNLQLGVSLTPEQV 1915
Query 2179 AQLTSDIVWLVEQSVTLPDGTITKALVPQVYVKVRVGDLKGDGTLLSGNSVNLKLDGDLI 2238
A L+ +VW +++T+ T+ L P++Y+ + G+ + NSV+L GD+
Sbjct 1916 AGLSHSLVWW--ENITVGGQTV---LAPKLYL-AQADKTNLQGSRIVANSVSLSAGGDID 1969
Query 2239 N-GATIAGREALQI-TADNVQNLNGRI--QGNQVAIETQKDLNNIGGQIIAKDAMALKVG 2294
N G+T+ ++AL + + N+ N G + G + + +L N I VG
Sbjct 1970 NRGSTVTAQDALAVASGGNLTNSEGGLLNAGGALNLVALGNLTNSSATIQGNTVTLASVG 2029
Query 2295 GNLNIESTTRTSE----SKVGNFSSSITNVD-RVAGLYVGNGSTKQLDPNQATLMLNVAG 2349
G +I +TT T + ++ G S+T D AGL G L L
Sbjct 2030 G--DIVNTTTTDQWQTAARDGRGRGSLTRTDIGQAGLISAQGG----------LTLQAGH 2077
Query 2350 NSSLKGVQINNSNSATVLNTTGNVDLGTVSVGKQETLKIDDKNGYQLKQQQDVGSQIKSA 2409
+ +L G Q+ S + GN T +T++ D + + Q V S + S
Sbjct 2078 DIALNGAQL--SAGGPLQLAAGNDIRLTALSTVTDTVRQDGGATTERRGQGLVQSTVASG 2135
Query 2410 GSLLIN-GQNITSKAVDLNSQQGDIQLSAQKDIVLDNGLNQSTVSSQSQSKGSFGGKKSS 2468
G L ++ G++++ A L S G + LSA +D+ S +S+ + S K+
Sbjct 2136 GDLSLSAGRDLSGTAAQL-SAAGTLALSAGRDL--------SLLSASEEQFSSNAWKRHL 2186
Query 2469 TYDASSSTSIANQLNAGQNIIINSAQGNISATHLQAEAGNNIQIHAQQGNVTLLSAIDDK 2528
+ + T LNAG+ + + + Q +++ QAE + A + +++LLSA + +
Sbjct 2187 DWQ-QTVTQQGTVLNAGEGLSLRAGQ-DLTLQGAQAETRGALTAQAGR-DLSLLSATESR 2243
Query 2529 RE--SSTSSKKGVATYNNRQSGYIDQEVAQTTLKAGDTVDINAAKNIELQANDVQAGNSI 2586
+ T+ KKG + ++ + + +E QTT K + +A ++ L AG+ I
Sbjct 2244 HDFFEETTVKKG---FLSKTTTHTLRETQQTTEKG----TLLSAGSVAL-----TAGHDI 2291
Query 2587 YVGNTLMQRQADGSLKAADGSLMPENVTLSTLATKDEQWDEQQKGYRGIVKDIVKATAVG 2646
V GS AADG VTL+ A D + YR + K + V
Sbjct 2292 GV---------QGSAVAADG-----EVTLT--AGNDITTAASVETYRNYEEQSRKKSGVF 2335
Query 2647 LAGIEALAPGLKAPKITVSESTGKRTEQISQTGSSLKADNVYVGSSGQTTLTSTDITAKN 2706
G G + + T+ + +++ +S GS+ +V + + ++ +TD+ A
Sbjct 2336 SGGGIGFTIGSTSLRQTLESAGTTQSQSVSTLGST--GGSVRLNAGQAVSMAATDVIAAR 2393
Query 2707 TI-LLGQKVTLNAAEEQKITVESTSKETVQGLGAKLNKDSIRLGGFVLEDASQSSKTTET 2765
I + G VT++ + + ++T GL ++ L G V + + +T +
Sbjct 2394 DIQVTGNSVTIDPGYDTRKQSRQMEQKTA-GL-------TVTLSGVVGSALNSAVQTVQA 2445
Query 2766 THKLGSINTENLKIQGVEGVDILGQNITATGDTLIDHGRGDLNVGGYENKTTVEDKTHVE 2825
+ + ++Q ++G+ + GY+ + T+ +
Sbjct 2446 VRE-----QSDSRLQALQGMKAA--------------------LSGYQAYQGTQIDTNNQ 2480
Query 2826 TISTEVGVRNAYLDAALALGAVKDAAEAVKQAKDQYS---QAQRDYA----SGKITKEAL 2878
S+ VG+ +++LGA + ++ + ++ A D + G IT
Sbjct 2481 GASSFVGI-------SVSLGAQRSSSSQTSEQSQSFASTLNAGHDISVVARQGDITAVGS 2533
Query 2879 DDSKANVAMATANLANAQIAVGSAAATAAASSATYG-----FTIGANGERIETTNTTNTT 2933
AN A+ A ++ + + ++S++ G F + +G N
Sbjct 2534 QLKAANNVELNASRAINLLSARNTESMTGSNSSSGGNIGVSFGLSNSGAGFSVFANVNAA 2593
Query 2934 QGKWQGSTLELNNLTLKSENQDVNVQGSRLTATGTTSFDGTKDLNVTAGTEHSQQETSSK 2993
+G+ G+ + T+ + Q G TG NV Q+ S++
Sbjct 2594 KGRELGNGNSWSETTVDAGQQIALTSGGDTRLTGAQVSGERIVANVGGDLLLKSQQDSNR 2653
Query 2994 TNSQSVSYTYGGGGSASIGKQTST 3017
+S+ S + GGS + G T +
Sbjct 2654 YDSKQTSVS--AGGSFTFGSMTGS 2675
Score = 99.8 bits (247), Expect = 9e-23
Identities = 395/1944 (20%), Positives = 702/1944 (36%), Gaps = 336/1944 (17%)
Query 209 GVINADRFTLTTGQAVMNQGYLESFRVREGQITIQGKGLNGSLTPFTDVY-ARALQVNAG 267
G + A + +TT A+ N+G L ++ +Q LN + +Y A LQ+ G
Sbjct 1151 GTVQAGQLDITTDGALDNRGTLLGLT----RLALQAASLNNA--DGARLYSAGGLQLRTG 1204
Query 268 LYAKELNVV-LGQNDINVNDPTTSNVSPIQSNTSANNKPQFALDVGQLGGMYAGKIFLVG 326
++ + LG ++ P T + T A GQL G + G
Sbjct 1205 QLTQDGQLAALGDLRADIGTPFTF------TRTLAAG--------GQLTLAVTGDLVQAG 1250
Query 327 TEQGVGVRNAGSMNSTQSTLTLNANGDLTNTGNLIANQGQLQLNAENIKNTGNISSATSQ 386
T QG GV T+ + G LT G ++A G L+A I T
Sbjct 1251 TLQGHGV-------------TVTSTGTLTQQGRIVAGGGNSTLSAAAISQT--------- 1288
Query 387 VSLHSQNLDNSGLISSADELNIQQQGHVGNRGTLNAAR-IVVDAGSLANSGSIEQTGAQA 445
SG I L+++ G++ NRG + A ++V AG + +GS+ G
Sbjct 1289 ---------ESGSIQGGGPLSLRATGNIVNRGFVGTAGDLLVQAGGVMENGSLLYGGGNL 1339
Query 446 LDLKAGSMSNIGGKIGIAKTSSTGGNGSESGGGSQPVEPNNAAQDGGSLEVVNTDSTPTT 505
L A ++ G + GGS ++ + A S V+N+ T T
Sbjct 1340 QLLSAALVNRFGNILA---------------GGSLWIQRDAAGNASDS--VLNSSGTIET 1382
Query 506 PKTYETGYIHVRDQLNNDQGAIVAQGGIDLESNNGLDNQGGQLNLGRVKIQGERFNNDQG 565
+ G I VR +Q +G + ES + + + + I ERF
Sbjct 1383 QR----GDITVRTGTLTNQ----REGLVVTESGSTAADMPDWVGGTTIYIPVERFE---- 1430
Query 566 QLTVKQAEIQTNSLSNQSGQLISNQKLNIQTQTANNQ--KGKIQSVDQLDLNVANGLNNI 623
+K + + + +G + T N + V + + + ++ + NI
Sbjct 1431 --VIKDYLVYSFEHTPGAGS---------DSPTTYNYFYPFPLSHVSKQEFSASSKIVNI 1479
Query 624 EGQ-----IASGQQLNIQADQVNNQSGLIYSEQQGIELKANHAINNT--SGIIQAKTQLN 676
E + I S +NI + + N + +I SE+ I + N++ SG++
Sbjct 1480 ESKGGSSLIHSAGDINIFSSVLVNDASIIASEKN-ILMNGGVLKNSSYQSGVMSESLIYE 1538
Query 677 LASTQLDNTSGHIQA--ENIQQQHTTVNNTQGSIVAGQSL------ISTVDQFDNHQGLI 728
D+ +I+ E +++ + ++G ++ I T D+F
Sbjct 1539 YERDDKDDFLPYIEWLWEKTKREEGVSDYDYWEYLSGYNIHAYNRNILTNDRF------- 1591
Query 729 DAKNIQLTHQVLNNSGSIYADQNIKITGQHILNTGSIAAGQNIQLNTAKLQHEQAALIAA 788
K + Q++ G YA I+ G N + N+Q + A A
Sbjct 1592 --KYVLKDRQIIFTPGQTYA-ATIQAGGAITANFSQNISNTNLQPGSGGFMPAMATPTLA 1648
Query 789 GLDRQGKLTSTGDLDITAEQT-TLHGQSFAGQQLKVASKQQIDATNGQLQAKNIDLASDA 847
G++ G + + D + + G + +G VA Q N A D + +
Sbjct 1649 GVNALGPVGAQADRGLNGGTAGNVSGSTLSGAGNGVALAGQAGRLNAGYSAVTRDNTASS 1708
Query 848 GD----ISTRAATVIAEQLSLKSHDLIDNQQGTLSAQQL--------------NLTANRL 889
G + A A + L G L+ L +LT L
Sbjct 1709 GSALNPVGIPAGPGTAGGAPVAGASLTPVAPGALALSDLQAALAQGLQQLGSPSLTDYPL 1768
Query 890 DNTQG--HILHTGQDQLDLNFSQSLNNQLGEIRSNAAELNIKTALLNNTEGQVVHAGTQQ 947
+Q + T D L + +QLG++ NA +++ LL T G
Sbjct 1769 PTSQSGLFVADTAGDSRYLIRTNPTLSQLGQV-DNALFGDLR-GLLGQTPGTTAPVERSP 1826
Query 948 LNIQTAQLNGHLGHILSNGTLQLKA------------GTLDVSGGVTS----------AD 985
Q+ LG G L L A T +S V S
Sbjct 1827 TLTDPTQV---LGSSYLLGKLNLDAEHDYRFLGDAAFDTRYISNAVLSQTGQRYLNGVGS 1883
Query 986 QITIQANVLNNAQGQLIQRGTSNPLNLTIQQQLNNQAGLIQSATAT----DIKAGSLNNQ 1041
++ +++NA + + ++LT +Q L+ T + A L
Sbjct 1884 ELAQMQQLMDNAAAEKSRLNLQLGVSLTPEQVAGLSHSLVWWENITVGGQTVLAPKLYLA 1943
Query 1042 RGTLSSAQGQNL-----DVDVAGKLDNSQSGQIYAGNQAHLQVGSIDNSHQGQINAQQNL 1096
+ ++ QG + + G +DN S A G++ NS G +NA L
Sbjct 1944 QADKTNLQGSRIVANSVSLSAGGDIDNRGSTVTAQDALAVASGGNLTNSEGGLLNAGGAL 2003
Query 1097 QLTSQQQINNQSGQIVANGDVQIQSQG-----LNNSHGQMGSLQGGLSLNTGSDTLINQS 1151
L + + N S I N V + S G + + + G + + T I Q+
Sbjct 2004 NLVALGNLTNSSATIQGN-TVTLASVGGDIVNTTTTDQWQTAARDGRGRGSLTRTDIGQA 2062
Query 1152 GLIQAKKDIGIQAQR-IDNQQGQITTQGQAELISQAEIDNLEGAIAADLDVNIRSQGLNN 1210
GLI A+ + +QA I Q++ G +L AA D IR L+
Sbjct 2063 GLISAQGGLTLQAGHDIALNGAQLSAGGPLQL-------------AAGND--IRLTALST 2107
Query 1211 NKGQISSAQGNLTLNAGNGTLTNQAATIVSGKTLTLSANQLDNSNHGQINSQNNADISIV 1270
+ G T G G + + T+ SG L+LSA + + Q+++ +S
Sbjct 2108 VTDTVRQDGGATTERRGQGLVQS---TVASGGDLSLSAGRDLSGTAAQLSAAGTLALSAG 2164
Query 1271 KDINNTSGVIAAKQQLILSSQGLNNTTGQIGTVQGNLHIDAGSQLLNNQQGRIQSGQDLN 1330
+D++ +++A ++ S+ + Q Q ++AG L +++GQDL
Sbjct 2165 RDLS----LLSASEEQFSSNAWKRHLDWQQTVTQQGTVLNAGEGL------SLRAGQDLT 2214
Query 1331 LNATGIDNTQGQISSKNQLQL------DSREQLLNN---RQGTLSAENL-TIDSGELNND 1380
L + T+G ++++ L +SR ++G LS T+ + +
Sbjct 2215 LQGAQAE-TRGALTAQAGRDLSLLSATESRHDFFEETTVKKGFLSKTTTHTLRETQQTTE 2273
Query 1381 QGLIQAQQSIQIDTHQHNLSNTNSGAQGG-ILSQGNIQL---NNIQTLDNQQGYLASAQQ 1436
+G + + S+ + T H++ G QG + + G + L N+I T + + Y +Q
Sbjct 2274 KGTLLSAGSVAL-TAGHDI-----GVQGSAVAADGEVTLTAGNDITTAASVETYRNYEEQ 2327
Query 1437 LDLQANQVFNQNGTLLAAKQLNLQGTGQNQ-LLNNQSGQMLSMGGMNLNIDQINNKGKAN 1495
+ + VF+ G +L+ T ++ +QS L G ++ + N G+A
Sbjct 2328 -SRKKSGVFSGGGIGFTIGSTSLRQTLESAGTTQSQSVSTLGSTGGSVRL----NAGQA- 2381
Query 1496 TADADSHIMAAGELNITTQQLDNQNTLNTDPANTSIQ----GIDANTLNVTSKVLNNQSG 1551
+ A + ++AA ++ +T + +T + ++ G+ V LN+
Sbjct 2382 VSMAATDVIAARDIQVTGNSVTIDPGYDTRKQSRQMEQKTAGLTVTLSGVVGSALNSAVQ 2441
Query 1552 VIRSSADQNLNVQQALNNQSGQISSEKQLTLVGDQLEINNLNGQILAGTALDLIAQSLSG 1611
+++ +Q+ + QAL +S + G Q++ NN G ++ L AQ S
Sbjct 2442 TVQAVREQSDSRLQALQGMKAALSGYQAYQ--GTQIDTNNQGASSFVGISVSLGAQRSSS 2499
Query 1612 DGKLLSLGNAKLSLQNDYIHSSGAQLQANQDLSL-STKGNIINNGT-INAGNQLALNAAN 1669
S ++ S + L A D+S+ + +G+I G+ + A N + LNA+
Sbjct 2500 ------------SQTSEQSQSFASTLNAGHDISVVARQGDITAVGSQLKAANNVELNASR 2547
Query 1670 ITNQQAGKIESHDTRLTAQNTLNNTGLINGDFTRLQAET-LNNQGTG-RIYGTTLAIQAN 1727
N L+A+NT + TG + + L+N G G ++ A +
Sbjct 2548 AINL-----------LSARNTESMTGSNSSSGGNIGVSFGLSNSGAGFSVFANVNAAKGR 2596
Query 1728 TLNNQPDSTGTAPVIASRGDLHLGVQTLNNLSNPTDYTSQALIFSAGNLYLGAALDANDY 1787
L N + T + L G T L+ + + G+L L + D+N Y
Sbjct 2597 ELGNGNSWSETTVDAGQQIALTSGGDT--RLTGAQVSGERIVANVGGDLLLKSQQDSNRY 2654
Query 1788 ATGQADVIHNESATIESL-GDMNLSAKQINNINKYFKTEQVEVSRKDGLEKYCDAWCTFD 1846
+ Q V S T S+ G LSA Q
Sbjct 2655 DSKQTSVSAGGSFTFGSMTGSGYLSASQ-------------------------------- 2682
Query 1847 GNYYDGNPYEDWMRYYYSEITYETRTTESAPG-QIKAGGHLDLNGAQVVNDKSQILAGGE 1905
D M + + +T G I G H L+GA + + G
Sbjct 2683 ----------DKMHSSFDSVQQQTGLFAGKGGYDISVGNHTQLDGAVIGS------TAGA 2726
Query 1906 LKNEGGTIDSGTQIAGIRKIVNTGTQVKYWKYEGQWDNPFENSSET--TFDLSISQALGN 1963
KN +D+GT G I N G +P + S+ + L+ AL +
Sbjct 2727 DKNR---LDTGT--LGFSNIDNRAEFSVSHSGIGLSASPSLSMSDMLKSAALTAPSALMS 2781
Query 1964 QNLNQNQLSTVAVSNNQSAEHIQNSQTTQQEINGL--QTSNNNTQLNQTKDVDLDQLNLK 2021
N ST + + A I+N QQ+I GL + + N L+ D + +Q L+
Sbjct 2782 MGRGGNAGSTTYAAVSDGALIIRNQAGQQQDIAGLSREVEHANNALSPIFDKEKEQKRLQ 2841
Query 2022 DSQSQNAPQASAVETVQQQSATSA 2045
+Q A ++ ++ + A
Sbjct 2842 TAQMVGELGAQVMDVIRTEGEIRA 2865
Score = 64.3 bits (155), Expect = 4e-12
Identities = 236/1258 (19%), Positives = 458/1258 (36%), Gaps = 202/1258 (16%)
Query 2402 VGSQIKSAGSLLI---NGQNITSKAVDLNSQQGDIQLSAQKDIVLDNGLNQSTVSSQSQS 2458
VG Q A L + + N+ + NS + LSA DI DN STV++Q
Sbjct 1930 VGGQTVLAPKLYLAQADKTNLQGSRIVANS----VSLSAGGDI--DN--RGSTVTAQDAL 1981
Query 2459 KGSFGGKKSSTYDASSSTSIANQLNAGQNIIINSAQGNISATHLQAEAGNNIQIHAQQGN 2518
+ GG ++ S LNAG + + A GN++ + + GN + + + G+
Sbjct 1982 AVASGGNLTN--------SEGGLLNAGGALNL-VALGNLTNSSATIQ-GNTVTLASVGGD 2031
Query 2519 VTLLSAIDDKRESSTSSK-KGVATYNN-RQSGYIDQEVAQTTLKAGDTVDINAAKNIELQ 2576
+ + D + ++ + +G T + Q+G I + TL+AG + +N A+
Sbjct 2032 IVNTTTTDQWQTAARDGRGRGSLTRTDIGQAGLISAQ-GGLTLQAGHDIALNGAQLSAGG 2090
Query 2577 ANDVQAGNSIYVGN----TLMQRQADGSLKAADGSLMPENVTLSTLATKDEQWDEQQKGY 2632
+ AGN I + T RQ G+ G + + ST+A+ + +
Sbjct 2091 PLQLAAGNDIRLTALSTVTDTVRQDGGATTERRG----QGLVQSTVASGGDLSLSAGRDL 2146
Query 2633 RGIVKDIVKATAVGLAGIEALAPGLKAPKITVSESTGKRTEQISQTGSSLKADNVYVGSS 2692
G A + AG AL+ G ++ SE EQ S D
Sbjct 2147 SGT------AAQLSAAGTLALSAGRDLSLLSASE------EQFSSNAWKRHLD------- 2187
Query 2693 GQTTLTSTDITAKNTIL-LGQKVTLNAAEEQKITVESTSKETVQGLGAKLNKDSIRLG-- 2749
+T + T+L G+ ++L A ++ +T++ ET L A+ +D L
Sbjct 2188 -----WQQTVTQQGTVLNAGEGLSLRAGQD--LTLQGAQAETRGALTAQAGRDLSLLSAT 2240
Query 2750 --------------GFVLEDASQSSKTTETTHKLGSI-NTENLKIQGVEGVDILGQNITA 2794
GF+ + + + + T+ T + G++ + ++ + + + G + A
Sbjct 2241 ESRHDFFEETTVKKGFLSKTTTHTLRETQQTTEKGTLLSAGSVALTAGHDIGVQGSAVAA 2300
Query 2795 TGDTLIDHGRGDLNVGGYENKTTVEDKTHVETISTEVGVRNAYLDAALALGAVKDAAEAV 2854
G+ + G E E+++ ++ G + + ++ A
Sbjct 2301 DGEVTLTAGNDITTAASVETYRNYEEQSRKKSGVFSGGGIGFTIGSTSLRQTLESAGTTQ 2360
Query 2855 KQAKDQYSQ---AQRDYASGKITKEALDDSKANVAMATANLANAQIAVGSAAATAAASSA 2911
Q+ + R A ++ A D A T N + +
Sbjct 2361 SQSVSTLGSTGGSVRLNAGQAVSMAATDVIAARDIQVTGNSVTIDPGYDTRKQSRQMEQK 2420
Query 2912 TYGFTIGANGERIETTNTTNTTQGKWQGSTLELNNLTLKSENQDVNVQGSRLTATGTTSF 2971
T G T+ +G N+ T + + +S+++ +QG + +G ++
Sbjct 2421 TAGLTVTLSGVVGSALNSAVQT----------VQAVREQSDSRLQALQGMKAALSGYQAY 2470
Query 2972 DGTKDLNVTAGTEHSQQETSSKTNSQSVSYTYGGGGSASIGKQTSTSESKSLTYVNSEVT 3031
GT Q +T+++ S V + G S QTS + +N+
Sbjct 2471 QGT------------QIDTNNQGASSFVGISVSLGAQRSSSSQTSEQSQSFASTLNAGHD 2518
Query 3032 LNKTEGRLNSLNIKGGEVSIQDRGNLQVNN-IHVESLQDTAS--SSNSSRGGSIGGGYGS 3088
++ R + G ++ + L + I++ S ++T S SNSS GG+IG +G
Sbjct 2519 ISVV-ARQGDITAVGSQLKAANNVELNASRAINLLSARNTESMTGSNSSSGGNIGVSFGL 2577
Query 3089 GSK----NITASYNQSKG---SSDSAWVNTT------SKLLIGNAQNDANLDAMGVKNIT 3135
+ ++ A+ N +KG + ++W TT L G G + +
Sbjct 2578 SNSGAGFSVFANVNAAKGRELGNGNSWSETTVDAGQQIALTSGGDTRLTGAQVSGERIVA 2637
Query 3136 NIGGVIANANKNADGSLTDHKNL-----------NYTGNLELKDLQDHNNNNSSGFNVST 3184
N+GG + D + D K + TG+ L QD +++ T
Sbjct 2638 NVGGDLL-LKSQQDSNRYDSKQTSVSAGGSFTFGSMTGSGYLSASQDKMHSSFDSVQQQT 2696
Query 3185 NIGIPQGG--SKAASTAPKGSTTIGLNSSGQETEQLTKATLGQGSVTNAT--ADTNRDIN 3240
+ +GG + IG +++G + +L TLG ++ N + ++ I
Sbjct 2697 GLFAGKGGYDISVGNHTQLDGAVIG-STAGADKNRLDTGTLGFSNIDNRAEFSVSHSGIG 2755
Query 3241 NTQEITRDQTTGMLNGSVTVDHRLLS--ESGRA-----EIVKEQEQLIENFRQSAENLAK 3293
+ + + + + ++T L+S G A V + +I N +++A
Sbjct 2756 LSASPSLSMSDMLKSAALTAPSALMSMGRGGNAGSTTYAAVSDGALIIRNQAGQQQDIAG 2815
Query 3294 ALPDGVYKDKALQTLNDVQAKLYNLPSEYKEVGVVGNSVASELLKRGMESQDVEALFSKL 3353
+ + + AL + D + + L + + VG +G V + G E + V A +K
Sbjct 2816 LSREVEHANNALSPIFDKEKEQKRLQTA-QMVGELGAQVMDVIRTEG-EIRAVRAAEAKG 2873
Query 3354 DF-----FYAAKEFSEIQNQLTDLEKSGVNLETIFKQPKAGVNEQETIYAQGTDFETKVR 3408
D + K++ + + LT+ +++ Y G+D + +
Sbjct 2874 DVKRPPDNASEKDWDKYKKDLTETPAYKAVMQS---------------YGTGSDLQRATQ 2918
Query 3409 SQTTLGMTILSNIADLGNSIKDISESTGVDIEKVQLAVGLLISGPVRLVIESGKSMAVDS 3468
+ T + +A GN + ++ + S P + G +M D
Sbjct 2919 AAT----AAIQALAGGGNLQQALAGA----------------SAPYLAQLVKGVTMPAD- 2957
Query 3469 VVGEKVAQGVDILANSMTAAAHDTSVNTINNWTNPDKISELENSTGENKDASLKFANEV- 3527
E A DI AN+M H + + D ++ + G A L E+
Sbjct 2958 ---ESKATASDIAANAM---GHALMGAVVAQLSGKDAVAGAVGAAGGELTARLLIMKELY 3011
Query 3528 ---------QKDKQGAEYLINAASGIIVGGIAKGTVKNNNSDIDISKSGFEIGNINPI 3576
+ +KQ L + A+G + GIA G + ++ E ++ I
Sbjct 3012 SGRDTSDLTEAEKQSVSALASLAAG-LASGIASGNTTGAATGAQAGRNAVENNSLGDI 3068
Score = 61.6 bits (148), Expect = 3e-11
Identities = 236/1108 (21%), Positives = 392/1108 (35%), Gaps = 172/1108 (16%)
Query 2210 VKVRVGDLKGDGTLLSGNSVNLKLDGDLINGATIAGREALQITADNVQNLNGRIQGNQVA 2269
V + G L DG + +S+ + G L N +AG + L ITAD + N + + +
Sbjct 374 VDIGGGPLTNDGNITGLDSLTVTTTGALTNRGRLAG-QTLGITADALDNAGTLLGVDALT 432
Query 2270 IETQKDL-NNIGGQIIAKDAMALKVG-----GNLNIESTTRTSE------------SKVG 2311
+ N GQ ++ A L G G +S T++ +
Sbjct 433 LAIAGTARNQTSGQWLSNGAGRLTAGTLDNRGQWQGDSLDATADRLDNAGTLLGLSAMTL 492
Query 2312 NFSSSITNVDRV--AGLYVGNGSTKQLDPNQATLMLNVAGNSSLKGVQINNSNSATVLNT 2369
+ ++TN R+ G V + +T D T L + +S G QI++ +
Sbjct 493 TVNGALTNTGRLLTQGAAVLSAATADNDGEWQTGSLWLTADSLRNGGQIHSDGEVRI--- 549
Query 2370 TGNVDLGTVSVGKQETLKIDDKNGYQLKQQQDV--GSQIKSAGSLLINGQ-NITSKAVDL 2426
T+ + L+ + QL Q + ++ + G L G IT + +D
Sbjct 550 -------TLPTADGDPLRPTLRAARQLAQDVEAIGAGRLSNTGVLTAGGDGRITGRGLD- 601
Query 2427 NSQQGDIQLSAQKDIVLDNGLNQSTVSSQSQSKGSFGGKKSSTYDASSSTSIANQLNAGQ 2486
G + + + N + S++ S T A +L G
Sbjct 602 --NAGTLAAGGALTLAAGDLTNAGRLESRTLSLTGDSLDNGGTLLAEQ----GGELTLGG 655
Query 2487 NIIINSAQGNISATHLQAEAGNNIQIHAQQGNVTLLSAID-DKRESSTSSKKGVATYNNR 2545
+ + + +S Q +AG + QG LLSA D + ++ T
Sbjct 656 GLHVGADGRLLSNGDWQVQAGTVTSLGQWQGKTLLLSAASLDNGGALLATDAVTLTLTQG 715
Query 2546 QSGYIDQEV---------AQTTLKAGDTVDINAAKNIELQANDVQAGNSIYVGNTLMQRQ 2596
+G +V A T + GD + L + G + VG + +
Sbjct 716 YTGGAGSQVLGSGAVTLTADTVTQQGDI----GGDRLALTTGTLTNGGRL-VGLSQLDVT 770
Query 2597 ADGSL-KAADGSLMPENVTLSTLATKDEQWDEQQKGYRGIVKDIVKATAVGLAGIEALAP 2655
+ G L A GSL+ T AT D Q + D V A + G AL
Sbjct 771 SRGQLTNRATGSLLGNGTAGVTAATLDNAGSVQADTLT-LTADTV-TNAGRMQGTSALTL 828
Query 2656 GLKAPKITVSESTGKRTEQISQTGSSL----KADNVYVGSSGQTTLTSTDITAKNTILLG 2711
VS TG Q+ G++ ADN + +G+ +T++ I
Sbjct 829 N------GVSRYTGTDGSQLLSGGTATLAIDNADNAGLWQAGELRFRGASLTSRGQITGL 882
Query 2712 QKVTLNAAEEQKITVESTSKETVQGL----GAKLNKDS--IRLGGFVLEDASQSSKTTET 2765
+T++AA ++ ST + T +GL G + + LGGF S T +
Sbjct 883 DSLTVDAA-----SLTSTGQLTTRGLATLRGQRFDNGGTLTALGGFTAR--FSDSVTNQG 935
Query 2766 THKL-----GSINTENLKIQGVEGVDILGQNITATGDTLIDHGRGDLNVGGYENKTTVED 2820
+L GS+ T L +G D +T T DTL + G + G ++
Sbjct 936 GGQLLSGGTGSLTTGTLVNRGRWQSD----RLTLTADTLRNPG----TLLGLDDGNIQLT 987
Query 2821 KTHVETISTEVGVRNAYLDAALALGAVKDAAEAVKQAKDQYSQAQRDYASGKIT-----K 2875
+V ++VG + AL+L A QA+D +A R G IT
Sbjct 988 GAYVGEAGSQVGG-----NGALSLSAATIDQAGQWQARDVTLRATRLRNQGSITGSGQLT 1042
Query 2876 EALDDSKANVAMATANLANAQIAVGSAAATAAASSATYGFTIGA-------------NGE 2922
LD+ N+A AT L G+ + G T+ +G
Sbjct 1043 ATLDEQLENLAGATL-LGGTVWLGGATVSNGGQIQGRSGLTVQGGTLLDNQGGGQLLSGG 1101
Query 2923 RIETTNTTNTTQGKWQGSTLEL------NNLTLKSEN-------QDVN---VQGSRLTAT 2966
++ T T G QG L L N+ TL++++ Q N VQ +L T
Sbjct 1102 QLALGATQLTNAGWVQGQDLTLTTAQLDNSGTLQAQSGLTLHLPQWTNRGTVQAGQLDIT 1161
Query 2967 GTTSFDGTKDLNVTAGTEHSQQETSSKTNSQSVSYTYGGGGSASIGKQTSTSESKSLTYV 3026
+ D L G + +S N+ GG G+ T + +L +
Sbjct 1162 TDGALDNRGTL---LGLTRLALQAASLNNADGARLYSAGGLQLRTGQLTQDGQLAALGDL 1218
Query 3027 NSEVTLNKTEGRLNSLNIKGGEVSIQDRGNL-QVNNIHVESLQDTASSSNSSRGGSIGGG 3085
+++ T R + GG++++ G+L Q + + T++ + + +G + GG
Sbjct 1219 RADIGTPFTFTRTLA---AGGQLTLAVTGDLVQAGTLQGHGVTVTSTGTLTQQGRIVAGG 1275
Query 3086 YGSGSKNITASYNQSKGSSDSAWVNTTSKLLIGNAQNDANLDAMGVKNITNIG--GVIAN 3143
G+ ++A+ S+ G+ Q L NI N G G +
Sbjct 1276 ---GNSTLSAA--------------AISQTESGSIQGGGPLSLRATGNIVNRGFVGTAGD 1318
Query 3144 ANKNADGSLTDHKNLNYTGNLELKDLQDHNNNNSSGFNVSTNIGIPQGGSKAASTAPKGS 3203
A G + + L GNL+L S V+ I GGS G+
Sbjct 1319 LLVQAGGVMENGSLLYGGGNLQL----------LSAALVNRFGNILAGGSLWIQRDAAGN 1368
Query 3204 TTIG-LNSSGQETEQLTKATLGQGSVTN 3230
+ LNSSG Q T+ G++TN
Sbjct 1369 ASDSVLNSSGTIETQRGDITVRTGTLTN 1396
Score = 45.1 bits (105), Expect = 3e-06
Identities = 87/390 (22%), Positives = 139/390 (36%), Gaps = 47/390 (12%)
Query 2885 VAMATANLANAQIAVGSAAATAAASSATYGFTIG---ANGERIETTNTTNTTQGKWQGST 2941
V + +L N +G A T A + G + GE T T + QG+WQG +
Sbjct 140 VTLTADSLDNGGTLLGMDALTLAIAGTARNQASGQWLSQGESRLTAGTLDN-QGQWQGDS 198
Query 2942 LELNNLTLKSENQDVNVQGSRLTATGTTSFDGTKDLNV-------TAGTEHSQQETSSKT 2994
L + +++ Q + + LTA GT + T L A ++ + + +
Sbjct 199 LSVTADRIRNAGQLLGLSALTLTADGTLTNTATGTLLTQGAAVLRAATVDNDGEWQAGRL 258
Query 2995 NSQSVSYTYGGGGSASIGKQTSTSESKSLT-----YVNSEVTLNKTEGRLNSLNIKGGEV 3049
+ S GG + + S + LT N + TL T G L++ G V
Sbjct 259 RLTADSLRNGGRIQSDGALDVALSPAGVLTNTGTLAANGDTTL--TPGGLDN----RGAV 312
Query 3050 SIQDRGNLQVNNIHVESLQDTASSSNSSRGGSIGGGYGSGSKNITASYNQSKGSSDSAWV 3109
S+ RG+L V +++ A+ + GS G S + + W
Sbjct 313 SV--RGDLTVTGTDLDNAGQLAARGALTLTGSYAGAGSLYSDAALTLRGTTLANDGGRWQ 370
Query 3110 NTTSKLLIGNAQNDANLDAMGVKNITNIG-------------GVIANANKNADGSL-TDH 3155
T + G ND N+ + +T G G+ A+A NA L D
Sbjct 371 GQTVDIGGGPLTNDGNITGLDSLTVTTTGALTNRGRLAGQTLGITADALDNAGTLLGVDA 430
Query 3156 KNLNYTGNLELKDLQDHNNNNSSGFNVST--NIGIPQGGS--KAASTAPKGSTTIGLNS- 3210
L G + +N + T N G QG S A T +GL++
Sbjct 431 LTLAIAGTARNQTSGQWLSNGAGRLTAGTLDNRGQWQGDSLDATADRLDNAGTLLGLSAM 490
Query 3211 ----SGQETEQLTKATLGQGSVTNATADTN 3236
+G T T G ++ ATAD +
Sbjct 491 TLTVNGALTNTGRLLTQGAAVLSAATADND 520
Score = 42.7 bits (99), Expect = 1e-05
Identities = 100/475 (21%), Positives = 175/475 (37%), Gaps = 100/475 (21%)
Query 2244 AGREALQITADNVQNLNGRIQ-GNQVAIET-QKDLNNIGGQIIAKDAMALKVGGNLNIES 2301
A R + T++ Q+ + G+ +++ Q D+ +G Q+ A + + L +N+ S
Sbjct 2494 AQRSSSSQTSEQSQSFASTLNAGHDISVVARQGDITAVGSQLKAANNVELNASRAINLLS 2553
Query 2302 TTRTSESKVGNFSSS-------------------ITNVDRVAGLYVGNG---STKQLDPN 2339
R +ES G+ SSS NV+ G +GNG S +D
Sbjct 2554 A-RNTESMTGSNSSSGGNIGVSFGLSNSGAGFSVFANVNAAKGRELGNGNSWSETTVDAG 2612
Query 2340 QATLMLNVAGNSSLKGVQINNSNSATVLNTTGNVDLGTVSVGKQETLKIDDKNGYQLKQQ 2399
Q + L G++ L G Q+ S V N G++ L + D N Y KQ
Sbjct 2613 QQ-IALTSGGDTRLTGAQV--SGERIVANVGGDLLLKSQQ----------DSNRYDSKQ- 2658
Query 2400 QDVGSQIKSAGSLLINGQNITSKAVDLNSQQGDIQLSAQKDIVLDNGLNQSTVSSQSQSK 2459
+ + + GS S G LSA +D + S+ S Q
Sbjct 2659 ----TSVSAGGSFTFG------------SMTGSGYLSASQDKM------HSSFDSVQQQT 2696
Query 2460 GSFGGKKSSTYDASSSTSI------------ANQLNAGQ---NIIINSAQGNISATHLQA 2504
G F GK + T + N+L+ G + I N A+ ++S + +
Sbjct 2697 GLFAGKGGYDISVGNHTQLDGAVIGSTAGADKNRLDTGTLGFSNIDNRAEFSVSHSGIGL 2756
Query 2505 EAGNNIQIHAQQGNVTLLSAIDDKRESSTSSKKGVATYNNRQSG--YIDQEVAQTTLKAG 2562
A ++ + + L +A G TY G I + Q AG
Sbjct 2757 SASPSLSMSDMLKSAAL-TAPSALMSMGRGGNAGSTTYAAVSDGALIIRNQAGQQQDIAG 2815
Query 2563 DTVDINAAKNI-------ELQANDVQAGNSI-YVGNTLMQR-QADGSLKAADGSLMPENV 2613
+ ++ A N E + +Q + +G +M + +G ++A + +V
Sbjct 2816 LSREVEHANNALSPIFDKEKEQKRLQTAQMVGELGAQVMDVIRTEGEIRAVRAAEAKGDV 2875
Query 2614 TLSTLATKDEQWDEQQK------GYRGIVK------DIVKATAVGLAGIEALAPG 2656
++ WD+ +K Y+ +++ D+ +AT A I+ALA G
Sbjct 2876 KRPPDNASEKDWDKYKKDLTETPAYKAVMQSYGTGSDLQRATQAATAAIQALAGG 2930
Score = 40.8 bits (94), Expect = 6e-05
Identities = 75/344 (22%), Positives = 137/344 (40%), Gaps = 31/344 (9%)
Query 2718 AAEEQKITVE---STSKETVQGLGAKLNK-DSIRLGG-FVLEDASQSSKTTETTHKLGSI 2772
AAE+ ++ ++ S + E V GL L ++I +GG VL ++ +T + I
Sbjct 1896 AAEKSRLNLQLGVSLTPEQVAGLSHSLVWWENITVGGQTVLAPKLYLAQADKTNLQGSRI 1955
Query 2773 NTENLKIQGVEGVDILGQNITA-------TGDTLIDHGRGDLNVGGYENKTTVEDKTHVE 2825
++ + +D G +TA +G L + G LN GG N + + T+
Sbjct 1956 VANSVSLSAGGDIDNRGSTVTAQDALAVASGGNLTNSEGGLLNAGGALNLVALGNLTNSS 2015
Query 2826 TISTEVGVRNAYLDAALALGAVKDAAE-AVKQAKDQYSQAQRDY-------ASGKITKEA 2877
V A + + D + A + + + S + D A G +T +A
Sbjct 2016 ATIQGNTVTLASVGGDIVNTTTTDQWQTAARDGRGRGSLTRTDIGQAGLISAQGGLTLQA 2075
Query 2878 LDDSKANVAMATANLANAQIAVGSAAATAAASSATYGFTIGANGERIETTNTTNTTQGKW 2937
D N A +A Q+A G+ A S+ T T+ +G T QG
Sbjct 2076 GHDIALNGAQLSAG-GPLQLAAGNDIRLTALSTVTD--TVRQDGG----ATTERRGQGLV 2128
Query 2938 QGSTLELNNLTLKSENQDVNVQGSRLTATGTTSFDGTKDLNVTAGTEHSQQETSSKTNSQ 2997
Q + +L+L S +D++ ++L+A GT + +DL++ + +E + K +
Sbjct 2129 QSTVASGGDLSL-SAGRDLSGTAAQLSAAGTLALSAGRDLSLLSASEEQFSSNAWKRHLD 2187
Query 2998 SVSYTYGGGGSASIGKQTSTSESKSLTYVNSEVTLNKTEGRLNS 3041
G + G+ S + LT ++ +T G L +
Sbjct 2188 WQQTVTQQGTVLNAGEGLSLRAGQDLTLQGAQA---ETRGALTA 2228
Lambda K H a alpha
0.307 0.125 0.334 0.792 4.96
Gapped
Lambda K H a alpha sigma
0.267 0.0410 0.140 1.90 42.6 43.6
Effective search space used: 113938146
Database: 82f2c4205203f9b6fe090619b6431083.SwissProt.fasta
Posted date: May 9, 2024 7:39 PM
Number of letters in database: 32,152
Number of sequences in database: 10
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Neighboring words threshold: 11
Window for multiple hits: 40
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Data ...
