BLASTP 2.12.0+
Reference: Stephen F. Altschul, Thomas L. Madden, Alejandro A.
Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J.
Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of
protein database search programs", Nucleic Acids Res. 25:3389-3402.
Reference for composition-based statistics: Alejandro A. Schaffer,
L. Aravind, Thomas L. Madden, Sergei Shavirin, John L. Spouge, Yuri
I. Wolf, Eugene V. Koonin, and Stephen F. Altschul (2001),
"Improving the accuracy of PSI-BLAST protein database searches with
composition-based statistics and other refinements", Nucleic Acids
Res. 29:2994-3005.
Database: c8964fb2000ea49dcd60865e2deaca03.SwissProt.fasta
15 sequences; 3,810 total letters
Query= ACIAD0995
Length=265
Score E
Sequences producing significant alignments: (Bits) Value
A7B3K3 3alpha-hydroxysteroid dehydrogenase [Ruminococcus gnavus (... 126 1e-38
Q9KQH7 3-oxoacyl-[acyl-carrier-protein] reductase FabG [Vibrio ch... 119 3e-36
P39640 Dihydroanticapsin 7-dehydrogenase [Bacillus subtilis (stra... 118 1e-35
Q9X248 3-oxoacyl-[acyl-carrier-protein] reductase FabG [Thermotog... 116 5e-35
Q9WYG0 Uncharacterized oxidoreductase TM_0325 [Thermotoga maritim... 113 1e-33
P55336 3-oxoacyl-[acyl-carrier-protein] reductase FabG [Vibrio ha... 111 5e-33
P07914 3alpha-hydroxy bile acid-CoA-ester 3-dehydrogenase 1/3 [Cl... 111 6e-33
P0A2D0 3-oxoacyl-[acyl-carrier-protein] reductase FabG [Salmonell... 110 7e-33
P0A2C9 3-oxoacyl-[acyl-carrier-protein] reductase FabG [Salmonell... 110 7e-33
Q5RCH8 Peroxisomal trans-2-enoyl-CoA reductase [Pongo abelii] 111 1e-32
D4A1J4 Dehydrogenase/reductase SDR family member 6 [Rattus norveg... 110 1e-32
P0AEK2 3-oxoacyl-[acyl-carrier-protein] reductase FabG [Escherich... 108 4e-32
Q9BY49 Peroxisomal trans-2-enoyl-CoA reductase [Homo sapiens] 110 5e-32
Q9BUT1 Dehydrogenase/reductase SDR family member 6 [Homo sapiens] 108 6e-32
P72332 Nodulation protein G [Rhizobium sp. (strain N33)] 108 6e-32
>A7B3K3 3alpha-hydroxysteroid dehydrogenase [Ruminococcus gnavus
(strain ATCC 29149 / VPI C7-9)]
Length=250
Score = 126 bits (316), Expect = 1e-38
Identities = 83/260 (32%), Positives = 138/260 (53%), Gaps = 16/260 (6%)
Query 1 MSFQVEGKVAVVTGGSSGIGLAAVEILVAEGAKVAWCGRDEPRLAESKRTILEKYPHAGV 60
M ++ KVA+VTGG+ GIG A V+ + GA V+ G + + ++ + E YP A +
Sbjct 1 MFMMLKNKVAIVTGGTRGIGFAVVKKFIENGAAVSLWGSRQETVDQALEQLKELYPDAKI 60
Query 61 FTQVCNVLDKADVKHFAQAVKQHLGNVDMLINNAGQGRVSTFENTQDEDWMKELELKYFS 120
+ ++ D A V VK+ G VD+L+NNAG + ++F N Q E++ K ++L +
Sbjct 61 SGKYPSLKDTAQVTAMINQVKEEFGAVDILVNNAGISQSTSFYNYQPEEFQKIVDLNVTA 120
Query 121 VLHPIRSFLDDLKSSDIGSITNVNSLLALQPEPHMIATSSARAALLNLTHSLAHEFTQYK 180
V + ++ +K G I N +S++++ +P +++ A+ LT SLA E
Sbjct 121 VFNCSQAAAKIMKEQGGGVILNTSSMVSIYGQPSGCGYPASKFAVNGLTKSLARELGCDN 180
Query 181 VRVNSILLGMVESAQWKRRFETRSDVNQSWEEWTAN--IAKKRGIPMQRLGKPEEPARAL 238
+RVN++ G+ TR+D+ + E IA IP+ R+G+PE+ A A
Sbjct 181 IRVNAVAPGI-----------TRTDMVAALPEAVIKPLIAT---IPLGRVGEPEDIANAF 226
Query 239 VFLASPLASYTTGSTIDVSG 258
+FLAS +ASY TG + V G
Sbjct 227 LFLASDMASYVTGEILSVDG 246
>Q9KQH7 3-oxoacyl-[acyl-carrier-protein] reductase FabG [Vibrio
cholerae serotype O1 (strain ATCC 39315 / El Tor Inaba N16961)]
Length=244
Score = 119 bits (299), Expect = 3e-36
Identities = 81/255 (32%), Positives = 123/255 (48%), Gaps = 17/255 (7%)
Query 5 VEGKVAVVTGGSSGIGLAAVEILVAEGAKVAWCGRDEPRLAESKRTILEKYPHAGVFTQV 64
+EGKVA+VTG S GIG A E+L GAKV +ES + Y
Sbjct 3 LEGKVALVTGASRGIGKAIAELLAERGAKVIGTAT-----SESGAQAISDYLGDNGKGMA 57
Query 65 CNVLDKADVKHFAQAVKQHLGNVDMLINNAGQGRVSTFENTQDEDWMKELELKYFSVLHP 124
NV + ++ +A+ G VD+L+NNAG R + ++E+W +E S+
Sbjct 58 LNVTNPESIEAVLKAITDEFGGVDILVNNAGITRDNLLMRMKEEEWSDIMETNLTSIFRL 117
Query 125 IRSFLDDLKSSDIGSITNVNSLLALQPEPHMIATSSARAALLNLTHSLAHEFTQYKVRVN 184
++ L + G I NV S++ ++A+A ++ T S+A E V VN
Sbjct 118 SKAVLRGMMKKRQGRIINVGSVVGTMGNAGQANYAAAKAGVIGFTKSMAREVASRGVTVN 177
Query 185 SILLGMVESAQWKRRFETRSDVNQSWEEWTANIAKKRGIPMQRLGKPEEPARALVFLASP 244
++ G +E+ K + E+ TA +A+ +P RLG P E A A+ FLASP
Sbjct 178 TVAPGFIETDMTKALND---------EQRTATLAQ---VPAGRLGDPREIASAVAFLASP 225
Query 245 LASYTTGSTIDVSGG 259
A+Y TG T+ V+GG
Sbjct 226 EAAYITGETLHVNGG 240
>P39640 Dihydroanticapsin 7-dehydrogenase [Bacillus subtilis (strain
168)]
Length=253
Score = 118 bits (295), Expect = 1e-35
Identities = 78/253 (31%), Positives = 136/253 (54%), Gaps = 8/253 (3%)
Query 8 KVAVVTGGSSGIGLAAVEILVAEGAKVAWCGRDEPRLAESKRTILEKYPHAGVFTQVCNV 67
K ++TGG+SGIG AAV+ + + A V DE A+ + + ++ F Q ++
Sbjct 6 KTVLITGGASGIGYAAVQAFLGQQANVVVADIDE---AQGEAMVRKENNDRLHFVQT-DI 61
Query 68 LDKADVKHFAQAVKQHLGNVDMLINNAGQGRVSTFENTQDEDWMKELELKYFSVLHPIRS 127
D+A +H ++ G +D+LINNAG V+ + DW K L++ + +
Sbjct 62 TDEAACQHAVESAVHTFGGLDVLINNAGIEIVAPIHEMELSDWNKVLQVNLTGMFLMSKH 121
Query 128 FLDDLKSSDIGSITNVNSLLALQPEPHMIATSSARAALLNLTHSLAHEFTQYKVRVNSIL 187
L + ++ G+I N S+ L P + A ++++ +L LT S+A ++ ++++RVN +
Sbjct 122 ALKHMLAAGKGNIINTCSVGGLVAWPDIPAYNASKGGVLQLTKSMAVDYAKHQIRVNCVC 181
Query 188 LGMVESAQWKRRFETRSDVNQSWEEWTANIAKKRGIPMQRLGKPEEPARALVFLASPLAS 247
G++++ ++ F ++ + EE AK P+ RLGKPEE A ++FLAS L+S
Sbjct 182 PGIIDTPLNEKSFLENNE--GTLEEIKKEKAKVN--PLLRLGKPEEIANVMLFLASDLSS 237
Query 248 YTTGSTIDVSGGF 260
Y TGS I GG+
Sbjct 238 YMTGSAITADGGY 250
>Q9X248 3-oxoacyl-[acyl-carrier-protein] reductase FabG [Thermotoga
maritima (strain ATCC 43589 / DSM 3109 / JCM 10099 / NBRC
100826 / MSB8)]
Length=246
Score = 116 bits (291), Expect = 5e-35
Identities = 77/256 (30%), Positives = 125/256 (49%), Gaps = 14/256 (5%)
Query 4 QVEGKVAVVTGGSSGIGLAAVEILVAEGAKVAWCGRDEPRLAESKRTILEKYPHAGVFTQ 63
++EGKV ++TG +SGIG A + EGA V G +S E P V
Sbjct 2 RLEGKVCLITGAASGIGKATTLLFAQEGATVI-AGDISKENLDSLVKEAEGLP-GKVDPY 59
Query 64 VCNVLDKADVKHFAQAVKQHLGNVDMLINNAGQGRVSTFENTQDEDWMKELELKYFSVLH 123
V NV D+ +K + V Q G +D+L+NNAG R + ++EDW + + V +
Sbjct 60 VLNVTDRDQIKEVVEKVVQKYGRIDVLVNNAGITRDALLVRMKEEDWDAVINVNLKGVFN 119
Query 124 PIRSFLDDLKSSDIGSITNVNSLLALQPEPHMIATSSARAALLNLTHSLAHEFTQYKVRV 183
+ + + GSI NV+S++ + P ++++A ++ +T + A E +RV
Sbjct 120 VTQMVVPYMIKQRNGSIVNVSSVVGIYGNPGQTNYAASKAGVIGMTKTWAKELAGRNIRV 179
Query 184 NSILLGMVESAQWKRRFETRSDVNQSWEEWTANIAKKRGIPMQRLGKPEEPARALVFLAS 243
N++ G +E+ ++ E + S IP+ R GKPEE A+ ++FLAS
Sbjct 180 NAVAPGFIETPMTEKLPEKARETALS------------RIPLGRFGKPEEVAQVILFLAS 227
Query 244 PLASYTTGSTIDVSGG 259
+SY TG I + GG
Sbjct 228 DESSYVTGQVIGIDGG 243
>Q9WYG0 Uncharacterized oxidoreductase TM_0325 [Thermotoga maritima
(strain ATCC 43589 / DSM 3109 / JCM 10099 / NBRC 100826
/ MSB8)]
Length=251
Score = 113 bits (282), Expect = 1e-33
Identities = 83/260 (32%), Positives = 125/260 (48%), Gaps = 14/260 (5%)
Query 1 MSFQVEGKVAVVTGGSSGIGLAAVEILVAEGAKVAWCGRDEPRLAESKRTILEKYPHAG- 59
M+FQ GKV ++TG SGIG A + GAKVA E + E+ I A
Sbjct 1 MNFQ--GKVVLITGAGSGIGKKAAVMFAERGAKVAINDISEEKGKETVELIKSMGGEAAF 58
Query 60 VFTQVCNVLDKADVKHFAQAVKQHLGNVDMLINNAGQGRVSTFENTQDEDWMKELELKYF 119
+F V D + + + G +D+L+NNAG E T +ED+ K + +
Sbjct 59 IFGDVAK-----DAEQIVKKTVETFGRLDILVNNAGIVPYGNIEETSEEDFDKTMAVNVK 113
Query 120 SVLHPIRSFLDDLKSSDIGSITNVNSLLALQPEPHMIATSSARAALLNLTHSLAHEFTQY 179
+ ++ +K G I NV+S L P S ++AALL LT SLA ++ Y
Sbjct 114 GPFLLSKYAVEQMKKQGGGVIVNVSSEAGLIGIPRRCVYSVSKAALLGLTRSLAVDYVDY 173
Query 180 KVRVNSILLGMVESAQWKRRFETRSDVNQSWEEWTANIAKKRGIPMQRLGKPEEPARALV 239
+RVN++ G +S R + + + ++ T+ IPM+RLGK EE A A++
Sbjct 174 GIRVNAVCPGTTQSEGLMARVKASPNPEELLKKMTSR------IPMKRLGKEEEIAFAIL 227
Query 240 FLASPLASYTTGSTIDVSGG 259
F A A + TGS I++ GG
Sbjct 228 FAACDEAGFMTGSIINIDGG 247
>P55336 3-oxoacyl-[acyl-carrier-protein] reductase FabG [Vibrio
harveyi]
Length=244
Score = 111 bits (277), Expect = 5e-33
Identities = 75/255 (29%), Positives = 116/255 (45%), Gaps = 17/255 (7%)
Query 5 VEGKVAVVTGGSSGIGLAAVEILVAEGAKVAWCGRDEPRLAESKRTILEKYPHAGVFTQV 64
+EGK+A+VTG S GIG A E+LV GA V E A + E +
Sbjct 3 LEGKIALVTGASRGIGRAIAELLVERGATVIGTATSEGGAAAISEYLGENGKGLAL---- 58
Query 65 CNVLDKADVKHFAQAVKQHLGNVDMLINNAGQGRVSTFENTQDEDWMKELELKYFSVLHP 124
NV D ++ + + G +D+L+NNAG R + +D++W + +
Sbjct 59 -NVTDVESIEATLKTINDECGAIDILVNNAGITRDNLLMRMKDDEWNDIINTNLTPIYRM 117
Query 125 IRSFLDDLKSSDIGSITNVNSLLALQPEPHMIATSSARAALLNLTHSLAHEFTQYKVRVN 184
++ L + G I NV S++ ++A+A ++ T S+A E V VN
Sbjct 118 SKAVLRGMMKKRAGRIINVGSVVGTMGNAGQTNYAAAKAGVIGFTKSMAREVASRGVTVN 177
Query 185 SILLGMVESAQWKRRFETRSDVNQSWEEWTANIAKKRGIPMQRLGKPEEPARALVFLASP 244
++ G +E+ K + + A +P RLG P E A A+VFLASP
Sbjct 178 TVAPGFIETDMTKALNDDQ------------RAATLSNVPAGRLGDPREIASAVVFLASP 225
Query 245 LASYTTGSTIDVSGG 259
A+Y TG T+ V+GG
Sbjct 226 EAAYITGETLHVNGG 240
>P07914 3alpha-hydroxy bile acid-CoA-ester 3-dehydrogenase 1/3
[Clostridium scindens (strain JCM 10418 / VPI 12708)]
Length=249
Score = 111 bits (277), Expect = 6e-33
Identities = 73/256 (29%), Positives = 124/256 (48%), Gaps = 12/256 (5%)
Query 5 VEGKVAVVTGGSSGIGLAAVEILVAEGAKVAWCGRDEPRLAESKRTILEKYPHAGVFTQV 64
V+ K+ ++TGG+ GIG AA ++ + GAKV+ G + + + + E YP V
Sbjct 4 VQDKITIITGGTRGIGFAAAKLFIENGAKVSIFGETQEEVDTALAQLKELYPEEEVLGFA 63
Query 65 CNVLDKADVKHFAQAVKQHLGNVDMLINNAGQGRVSTFENTQDEDWMKELELKYFSVLHP 124
++ + V V Q G +D++INNAG S F +ED+ +++ V +
Sbjct 64 PDLTSRDAVMAAVGTVAQKYGRLDVMINNAGITMNSVFSRVSEEDFKNIMDINVNGVFNG 123
Query 125 IRSFLDDLKSSDIGSITNVNSLLALQPEPHMIATSSARAALLNLTHSLAHEFTQYKVRVN 184
S +K + G I N S+ + I +++A ++ LTH L E + +RV
Sbjct 124 AWSAYQCMKDAKQGVIINTASVTGIYGSLSGIGYPTSKAGVIGLTHGLGREIIRKNIRVV 183
Query 185 SILLGMVESAQWKRRFETRSDVNQSWEEWTANIAKKRGIPMQRLGKPEEPARALVFLASP 244
+ G+V++ T+ + E++ + +PM+R+ KPEE A +FLAS
Sbjct 184 GVAPGVVDTDM------TKGLPPEILEDYL------KTLPMKRMLKPEEIANVYLFLASD 231
Query 245 LASYTTGSTIDVSGGF 260
LAS T +TI V G +
Sbjct 232 LASGITATTISVDGAY 247
>P0A2D0 3-oxoacyl-[acyl-carrier-protein] reductase FabG [Salmonella
typhi]
Length=244
Score = 110 bits (276), Expect = 7e-33
Identities = 81/260 (31%), Positives = 126/260 (48%), Gaps = 21/260 (8%)
Query 1 MSFQVEGKVAVVTGGSSGIGLAAVEILVAEGAKVAWCGRDEPRLAESKRTILEKYPHAGV 60
MSF EGK+A+VTG S GIG A E LVA GAKV +E+ + Y A
Sbjct 1 MSF--EGKIALVTGASRGIGRAIAETLVARGAKVIGTAT-----SENGAKNISDYLGANG 53
Query 61 FTQVCNVLDKADVKHFAQAVKQHLGNVDMLINNAGQGRVSTFENTQDEDWMKELELKYFS 120
+ NV D A ++ + ++ G VD+L+NNAG R + +D++W +E S
Sbjct 54 KGLMLNVTDPASIESVLENIRAEFGEVDILVNNAGITRDNLLMRMKDDEWNDIIETNLSS 113
Query 121 VLHPIRSFLDDLKSSDIGSITNVNSLLALQPEPHMIATSSARAALLNLTHSLAHEFTQYK 180
V ++ + + G I + S++ ++A+A L+ + SLA E
Sbjct 114 VFRLSKAVMRAMMKKRCGRIITIGSVVGTMGNAGQANYAAAKAGLIGFSKSLAREVASRG 173
Query 181 VRVNSILLGMVESAQWKRRFETRSDVNQSW-EEWTANIAKKRGIPMQRLGKPEEPARALV 239
+ VN + G +E +D+ ++ ++ A I + +P RLG +E A A+
Sbjct 174 ITVNVVAPGFIE-----------TDMTRALSDDQRAGILAQ--VPAGRLGGAQEIASAVA 220
Query 240 FLASPLASYTTGSTIDVSGG 259
FLAS ASY TG T+ V+GG
Sbjct 221 FLASDEASYITGETLHVNGG 240
>P0A2C9 3-oxoacyl-[acyl-carrier-protein] reductase FabG [Salmonella
typhimurium (strain LT2 / SGSC1412 / ATCC 700720)]
Length=244
Score = 110 bits (276), Expect = 7e-33
Identities = 81/260 (31%), Positives = 126/260 (48%), Gaps = 21/260 (8%)
Query 1 MSFQVEGKVAVVTGGSSGIGLAAVEILVAEGAKVAWCGRDEPRLAESKRTILEKYPHAGV 60
MSF EGK+A+VTG S GIG A E LVA GAKV +E+ + Y A
Sbjct 1 MSF--EGKIALVTGASRGIGRAIAETLVARGAKVIGTAT-----SENGAKNISDYLGANG 53
Query 61 FTQVCNVLDKADVKHFAQAVKQHLGNVDMLINNAGQGRVSTFENTQDEDWMKELELKYFS 120
+ NV D A ++ + ++ G VD+L+NNAG R + +D++W +E S
Sbjct 54 KGLMLNVTDPASIESVLENIRAEFGEVDILVNNAGITRDNLLMRMKDDEWNDIIETNLSS 113
Query 121 VLHPIRSFLDDLKSSDIGSITNVNSLLALQPEPHMIATSSARAALLNLTHSLAHEFTQYK 180
V ++ + + G I + S++ ++A+A L+ + SLA E
Sbjct 114 VFRLSKAVMRAMMKKRCGRIITIGSVVGTMGNAGQANYAAAKAGLIGFSKSLAREVASRG 173
Query 181 VRVNSILLGMVESAQWKRRFETRSDVNQSW-EEWTANIAKKRGIPMQRLGKPEEPARALV 239
+ VN + G +E +D+ ++ ++ A I + +P RLG +E A A+
Sbjct 174 ITVNVVAPGFIE-----------TDMTRALSDDQRAGILAQ--VPAGRLGGAQEIASAVA 220
Query 240 FLASPLASYTTGSTIDVSGG 259
FLAS ASY TG T+ V+GG
Sbjct 221 FLASDEASYITGETLHVNGG 240
>Q5RCH8 Peroxisomal trans-2-enoyl-CoA reductase [Pongo abelii]
Length=303
Score = 111 bits (278), Expect = 1e-32
Identities = 77/259 (30%), Positives = 130/259 (50%), Gaps = 14/259 (5%)
Query 5 VEGKVAVVTGGSSGIGLAAVEILVAEGAKVAWCGRDEPRLAESKRTILEKYP---HAGVF 61
++G+VA+VTGG++GIG A V+ L+ G+ V R RL + + P A V
Sbjct 16 LQGQVAIVTGGATGIGKAIVKELLELGSNVVIASRKLERLKSAAGELQANLPPTKQARVI 75
Query 62 TQVCNVLDKADVKHFAQAVKQHLGNVDMLINNAGQGRVSTFENTQDEDWMKELELKYFSV 121
CN+ ++ +V + ++ G ++ L+NN G +S E+ + W LE
Sbjct 76 PIQCNIRNEEEVNNLVKSTLDIFGKINFLVNNGGGQFLSLAEHISSKGWHAVLETNLTGT 135
Query 122 LHPIRSFLDDLKSSDIGSITNVNSLLALQPE-PHMIATSSARAALLNLTHSLAHEFTQYK 180
+ ++ GSI N+ +++++ P + + +ARA + NLT SLA E+
Sbjct 136 FYMCKAVYSSWMKEHGGSIVNI--IVSIKTGLPLAVHSGAARAGVYNLTKSLALEWACSG 193
Query 181 VRVNSILLGMVESAQWKRRFETRSDVNQSWEEWTANIAKKRGIPMQRLGKPEEPARALVF 240
VR+N + G++ S + E QS+ E + + IP +R+G PEE + + F
Sbjct 194 VRINCVAPGVIYS---QTAVENYGSYGQSFFEESF-----QKIPAKRIGVPEEVSSVVCF 245
Query 241 LASPLASYTTGSTIDVSGG 259
L SP AS+ TG ++DV GG
Sbjct 246 LLSPAASFITGQSVDVDGG 264
>D4A1J4 Dehydrogenase/reductase SDR family member 6 [Rattus norvegicus]
Length=245
Score = 110 bits (274), Expect = 1e-32
Identities = 77/259 (30%), Positives = 136/259 (53%), Gaps = 18/259 (7%)
Query 4 QVEGKVAVVTGGSSGIGLAAVEILVAEGAKVAWCGRDEPRLAESKRTILEKYPHAGVFTQ 63
++EGKV V+T + GIG A+ EGAKV +E +L E LE YP G+ T+
Sbjct 3 RLEGKVIVLTAAAQGIGRASALAFAREGAKVIATDINEAKLQE-----LENYP--GIQTR 55
Query 64 VCNVLDKADVKHFAQAVKQHLGNVDMLINNAGQGRVSTFENTQDEDWMKELELKYFSVLH 123
V +V K + FA +++ +D+L N AG T + +++DW + L S+
Sbjct 56 VLDVTKKRQIDQFASEIEK----IDVLFNVAGFVHHGTILDCEEKDWDFSMNLNVRSMYL 111
Query 124 PIRSFLDDLKSSDIGSITNVNSLL-ALQPEPHMIATSSARAALLNLTHSLAHEFTQYKVR 182
I++FL + + G+I N++S+ +++ + S+ +AA++ LT S+A +F Q +R
Sbjct 112 MIKAFLPKMLAQKSGNIINMSSVASSIKGVENRCVYSATKAAVIGLTKSVAADFIQQGIR 171
Query 183 VNSILLGMVESAQWKRRFETRSDVNQSWEEWTANIAKKRGIPMQRLGKPEEPARALVFLA 242
N + G V++ + R + R D ++ + + +K G R EE A V+LA
Sbjct 172 CNCVCPGTVDTPSLQERIQARDDPKEALKAFLNR--QKTG----RFASAEEVALLCVYLA 225
Query 243 SPLASYTTGSTIDVSGGFN 261
S ++Y TG+ + + GG++
Sbjct 226 SDESAYVTGTPVVIDGGWS 244
>P0AEK2 3-oxoacyl-[acyl-carrier-protein] reductase FabG [Escherichia
coli (strain K12)]
Length=244
Score = 108 bits (271), Expect = 4e-32
Identities = 77/255 (30%), Positives = 122/255 (48%), Gaps = 19/255 (7%)
Query 6 EGKVAVVTGGSSGIGLAAVEILVAEGAKVAWCGRDEPRLAESKRTILEKYPHAGVFTQVC 65
EGK+A+VTG S GIG A E L A GAKV +E+ + Y A +
Sbjct 4 EGKIALVTGASRGIGRAIAETLAARGAKVIGTAT-----SENGAQAISDYLGANGKGLML 58
Query 66 NVLDKADVKHFAQAVKQHLGNVDMLINNAGQGRVSTFENTQDEDWMKELELKYFSVLHPI 125
NV D A ++ + ++ G VD+L+NNAG R + +DE+W +E SV
Sbjct 59 NVTDPASIESVLEKIRAEFGEVDILVNNAGITRDNLLMRMKDEEWNDIIETNLSSVFRLS 118
Query 126 RSFLDDLKSSDIGSITNVNSLLALQPEPHMIATSSARAALLNLTHSLAHEFTQYKVRVNS 185
++ + + G I + S++ ++A+A L+ + SLA E + VN
Sbjct 119 KAVMRAMMKKRHGRIITIGSVVGTMGNGGQANYAAAKAGLIGFSKSLAREVASRGITVNV 178
Query 186 ILLGMVESAQWKRRFETRSDVNQSW-EEWTANIAKKRGIPMQRLGKPEEPARALVFLASP 244
+ G +E +D+ ++ ++ A I + +P RLG +E A A+ FLAS
Sbjct 179 VAPGFIE-----------TDMTRALSDDQRAGILAQ--VPAGRLGGAQEIANAVAFLASD 225
Query 245 LASYTTGSTIDVSGG 259
A+Y TG T+ V+GG
Sbjct 226 EAAYITGETLHVNGG 240
>Q9BY49 Peroxisomal trans-2-enoyl-CoA reductase [Homo sapiens]
Length=303
Score = 110 bits (274), Expect = 5e-32
Identities = 76/258 (29%), Positives = 126/258 (49%), Gaps = 12/258 (5%)
Query 5 VEGKVAVVTGGSSGIGLAAVEILVAEGAKVAWCGRDEPRLAESKRTILEKYP---HAGVF 61
++G+VA+VTGG++GIG A V+ L+ G+ V R RL + + P A V
Sbjct 16 LQGQVAIVTGGATGIGKAIVKELLELGSNVVIASRKLERLKSAADELQANLPPTKQARVI 75
Query 62 TQVCNVLDKADVKHFAQAVKQHLGNVDMLINNAGQGRVSTFENTQDEDWMKELELKYFSV 121
CN+ ++ +V + ++ G ++ L+NN G +S E+ + W LE
Sbjct 76 PIQCNIRNEEEVNNLVKSTLDTFGKINFLVNNGGGQFLSPAEHISSKGWHAVLETNLTGT 135
Query 122 LHPIRSFLDDLKSSDIGSITNVNSLLALQPEPHMIATSSARAALLNLTHSLAHEFTQYKV 181
+ ++ GSI N+ + P + + +ARA + NLT SLA E+ +
Sbjct 136 FYMCKAVYSSWMKEHGGSIVNI-IVPTKAGFPLAVHSGAARAGVYNLTKSLALEWACSGI 194
Query 182 RVNSILLGMVESAQWKRRFETRSDVNQSWEEWTANIAKKRGIPMQRLGKPEEPARALVFL 241
R+N + G++ S + E QS+ E + + IP +R+G PEE + + FL
Sbjct 195 RINCVAPGVIYS---QTAVENYGSWGQSFFEGSF-----QKIPAKRIGVPEEVSSVVCFL 246
Query 242 ASPLASYTTGSTIDVSGG 259
SP AS+ TG ++DV GG
Sbjct 247 LSPAASFITGQSVDVDGG 264
>Q9BUT1 Dehydrogenase/reductase SDR family member 6 [Homo sapiens]
Length=245
Score = 108 bits (270), Expect = 6e-32
Identities = 77/259 (30%), Positives = 137/259 (53%), Gaps = 18/259 (7%)
Query 4 QVEGKVAVVTGGSSGIGLAAVEILVAEGAKVAWCGRDEPRLAESKRTILEKYPHAGVFTQ 63
+++GKV ++T + GIG AA EGAKV +E +L E LEKYP G+ T+
Sbjct 3 RLDGKVIILTAAAQGIGQAAALAFAREGAKVIATDINESKLQE-----LEKYP--GIQTR 55
Query 64 VCNVLDKADVKHFAQAVKQHLGNVDMLINNAGQGRVSTFENTQDEDWMKELELKYFSVLH 123
V +V K + FA V++ +D+L N AG T + +++DW + L S+
Sbjct 56 VLDVTKKKQIDQFANEVER----LDVLFNVAGFVHHGTVLDCEEKDWDFSMNLNVRSMYL 111
Query 124 PIRSFLDDLKSSDIGSITNVNSLL-ALQPEPHMIATSSARAALLNLTHSLAHEFTQYKVR 182
I++FL + + G+I N++S+ +++ + S+ +AA++ LT S+A +F Q +R
Sbjct 112 MIKAFLPKMLAQKSGNIINMSSVASSVKGVVNRCVYSTTKAAVIGLTKSVAADFIQQGIR 171
Query 183 VNSILLGMVESAQWKRRFETRSDVNQSWEEWTANIAKKRGIPMQRLGKPEEPARALVFLA 242
N + G V++ + R + R + ++ ++ +K G R EE A V+LA
Sbjct 172 CNCVCPGTVDTPSLQERIQARGNPEEARNDFLKR--QKTG----RFATAEEIAMLCVYLA 225
Query 243 SPLASYTTGSTIDVSGGFN 261
S ++Y TG+ + + GG++
Sbjct 226 SDESAYVTGNPVIIDGGWS 244
>P72332 Nodulation protein G [Rhizobium sp. (strain N33)]
Length=245
Score = 108 bits (270), Expect = 6e-32
Identities = 78/257 (30%), Positives = 121/257 (47%), Gaps = 17/257 (7%)
Query 3 FQVEGKVAVVTGGSSGIGLAAVEILVAEGAKVAWCGRDEPRLAESKRTILEKYPHAGVFT 62
F++ G+ A+VTG S GIG A +L A+GA V G R+ + + E +F
Sbjct 2 FELTGRKALVTGASGGIGEAIARVLHAQGAIVGLHGT---RVEKLETLAAELGDRVKLFP 58
Query 63 QVCNVLDKADVKHFAQAVKQHLGNVDMLINNAGQGRVSTFENTQDEDWMKELELKYFSVL 122
N+ ++ +VK Q + L VD+L+NNAG + F D DW LE+ +V
Sbjct 59 --ANLSNRDEVKALGQKAEADLEGVDILVNNAGITKDGLFVRMSDADWDTVLEVNLTAVF 116
Query 123 HPIRSFLDDLKSSDIGSITNVNSLLALQPEPHMIATSSARAALLNLTHSLAHEFTQYKVR 182
R + G I N+ S++ + P +++A ++ + SLA E +
Sbjct 117 RLTRELTHPMMRRRHGRIINITSVVGVTGNPGQTNYCASKAGMIGFSKSLAQEIATRNIT 176
Query 183 VNSILLGMVESAQWKRRFETRSDVNQSWEEWTANIAKKRGIPMQRLGKPEEPARALVFLA 242
VN + G +ESA + +N +E A IP +R+G E A A+ +LA
Sbjct 177 VNCVAPGFIESAMTDK-------LNDKQKE-----AIMAAIPTRRMGTSVEVASAVAYLA 224
Query 243 SPLASYTTGSTIDVSGG 259
S A+Y TG TI V+GG
Sbjct 225 SNEAAYVTGQTIHVNGG 241
Lambda K H a alpha
0.319 0.132 0.388 0.792 4.96
Gapped
Lambda K H a alpha sigma
0.267 0.0410 0.140 1.90 42.6 43.6
Effective search space used: 702630
Database: c8964fb2000ea49dcd60865e2deaca03.SwissProt.fasta
Posted date: May 19, 2024 7:24 PM
Number of letters in database: 3,810
Number of sequences in database: 15
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Neighboring words threshold: 11
Window for multiple hits: 40
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Data ...
