BLASTP 2.12.0+
Reference: Stephen F. Altschul, Thomas L. Madden, Alejandro A.
Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J.
Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of
protein database search programs", Nucleic Acids Res. 25:3389-3402.
Reference for composition-based statistics: Alejandro A. Schaffer,
L. Aravind, Thomas L. Madden, Sergei Shavirin, John L. Spouge, Yuri
I. Wolf, Eugene V. Koonin, and Stephen F. Altschul (2001),
"Improving the accuracy of PSI-BLAST protein database searches with
composition-based statistics and other refinements", Nucleic Acids
Res. 29:2994-3005.
Database: 55dc12a402cc85bbbf917edd20a71488.SwissProt.fasta
19 sequences; 9,443 total letters
Query= ACIAD0998
Length=489
Score E
Sequences producing significant alignments: (Bits) Value
A8GBX8 Betaine aldehyde dehydrogenase [Serratia proteamaculans (s... 362 5e-124
Q3K5H4 Betaine aldehyde dehydrogenase [Pseudomonas fluorescens (s... 362 5e-124
B7V5R4 Betaine aldehyde dehydrogenase [Pseudomonas aeruginosa (st... 362 1e-123
Q9HTJ1 NAD/NADP-dependent betaine aldehyde dehydrogenase [Pseudom... 362 1e-123
P71016 Betaine aldehyde dehydrogenase [Bacillus subtilis (strain ... 360 3e-123
A4VKC2 Betaine aldehyde dehydrogenase [Stutzerimonas stutzeri (st... 360 3e-123
A6ZR27 Aldehyde dehydrogenase 5, mitochondrial [Saccharomyces cer... 361 3e-123
P40047 Aldehyde dehydrogenase 5, mitochondrial [Saccharomyces cer... 361 3e-123
A6VEI4 Betaine aldehyde dehydrogenase [Pseudomonas aeruginosa (st... 359 8e-123
Q4K4K8 Betaine aldehyde dehydrogenase [Pseudomonas fluorescens (s... 358 2e-122
Q2YV11 Putative aldehyde dehydrogenase AldA [Staphylococcus aureu... 358 4e-122
Q02DY9 Betaine aldehyde dehydrogenase [Pseudomonas aeruginosa (st... 357 4e-122
O34660 Putative aldehyde dehydrogenase DhaS [Bacillus subtilis (s... 354 1e-120
O06837 Phenylacetaldehyde dehydrogenase [Pseudomonas fluorescens] 344 8e-117
P46367 Potassium-activated aldehyde dehydrogenase, mitochondrial ... 342 8e-116
Q6F9F7 (Z)-2-((N-methylformamido)methylene)-5-hydroxybutyrolacton... 332 3e-112
P08157 Aldehyde dehydrogenase [Emericella nidulans (strain FGSC A... 332 4e-112
Q27640 Aldehyde dehydrogenase [Enchytraeus buchholzi] 331 1e-111
P54115 Magnesium-activated aldehyde dehydrogenase, cytosolic [Sac... 331 1e-111
>A8GBX8 Betaine aldehyde dehydrogenase [Serratia proteamaculans
(strain 568)]
Length=490
Score = 362 bits (930), Expect = 5e-124
Identities = 192/483 (40%), Positives = 293/483 (61%), Gaps = 6/483 (1%)
Query 2 VKELYIAGEWRLGR-GKVIQSTFPADNSVNAEISTASFEDIEEAIVKADQAWRAPEWRNR 60
+++LYI G + GK + PA+ V AEI +AS ED+ A+ A + W
Sbjct 6 LQKLYINGAYVDSTDGKTFNAVNPANGEVLAEIQSASAEDVNRAVASAASGQKV--WAAM 63
Query 61 LPHERAKILYKVADIIEARVDALAALQTRDNGKPLAETRGL-VFSAAATARYVAAACETM 119
R++IL + DI+ R D LAAL+T D GK ++ET + + + A Y A ++
Sbjct 64 TAMARSRILRRAVDILRERNDELAALETLDTGKAMSETTAVDIVTGADVLEYYAGLIPSI 123
Query 120 NDELTSQRAPDFMTFSVHEPVGVVAAITPWNSPIASEVQKLAPALAGGNAVILKPAEATS 179
+ R F+ ++ EP+GVVA I WN PI + K APALA GNA+I KP+E TS
Sbjct 124 EGQQIPLRDTSFV-YTRREPLGVVAGIGAWNYPIQIALWKSAPALAAGNAMIFKPSEVTS 182
Query 180 LIALELAKIFEEAGLPKGLLSVLVGKGSVVGDAIVKHPLVRKISFTGGTTTGRH-LAHIA 238
L AL+LA+I+ EAGLP G+ +V+ G G+ VG + HP + K+SFTGG TG+ +A+ +
Sbjct 183 LTALKLAEIYTEAGLPDGVFNVVTGSGAEVGQYLTDHPGIAKVSFTGGVKTGKKVMANAS 242
Query 239 ADKLITTSLELGGKSPTIVLPDADIELAAKGIAYGIFSSAGQACIAGSRLFIHSSIYDQF 298
L ++ELGGKSP I+ DAD++ AA F S+GQ C G+R+F+ +++ QF
Sbjct 243 GSTLKEVTMELGGKSPLIIFDDADLDRAADIAMMANFYSSGQVCTNGTRVFVPAALQAQF 302
Query 299 LARLVEITKSLRVGHPEQKDVHMGSLINAAHLASVDRYVQLAKQEGGEILTGGQAMTEGE 358
A+++E K +R+G P + G L++ AH+ SV R+++ K G +L GG+ +TEGE
Sbjct 303 EAKILERVKRIRLGDPTDPQTNFGPLVSFAHMESVLRFIESGKNSGARLLCGGERVTEGE 362
Query 359 FAKGSFYLPTIITGLKNQAQVCQEEIFGPVLVVMKYEHEDDLIEQANDSCFGLAAGIWTE 418
FAKG++ PT+ T +++ ++ +EEIFGPV+ ++ Y+ E++++ +AND+ FGLAAG+ T
Sbjct 363 FAKGAYVAPTVFTDCRDEMEIVREEIFGPVMSILSYQSEEEVVRRANDTTFGLAAGVVTN 422
Query 419 SYRKAWRIARVLEVGTVWINTYKKFSISAPFGGFKDSGIGREKGRQGILSYMQQKSIYMG 478
+A R+ LE G WINT+ + + P GG+K SG+GRE G + Y Q KS+ +
Sbjct 423 DLTRAHRVIHQLEAGICWINTWGESAAEMPVGGYKQSGVGRENGLMTLEHYTQIKSVQVE 482
Query 479 LNE 481
L E
Sbjct 483 LGE 485
>Q3K5H4 Betaine aldehyde dehydrogenase [Pseudomonas fluorescens
(strain Pf0-1)]
Length=490
Score = 362 bits (930), Expect = 5e-124
Identities = 195/483 (40%), Positives = 291/483 (60%), Gaps = 6/483 (1%)
Query 2 VKELYIAGEWR-LGRGKVIQSTFPADNSVNAEISTASFEDIEEAIVKADQAWRAPEWRNR 60
+++LYI G + G ++ PA+ V A + A+ ED+E A+V A++ + W
Sbjct 6 LQKLYIDGAYSDAGSDATFEAINPANGEVLAHVQRATKEDVERAVVSAEKGQKI--WAAM 63
Query 61 LPHERAKILYKVADIIEARVDALAALQTRDNGKPLAETRGL-VFSAAATARYVAAACETM 119
ER++IL + DI+ R D LAAL+T D GK +ET+ + + + A Y A +
Sbjct 64 TAMERSRILRRAVDILRERNDELAALETLDTGKAFSETKYVDIVTGADVLEYYAGLVPAI 123
Query 120 NDELTSQRAPDFMTFSVHEPVGVVAAITPWNSPIASEVQKLAPALAGGNAVILKPAEATS 179
E R F+ ++ EP+GVVA I WN PI + K APALA GNA+I KP+E TS
Sbjct 124 EGEQIPLRDTSFV-YTRREPLGVVAGIGAWNYPIQIALWKSAPALAAGNAMIFKPSEVTS 182
Query 180 LIALELAKIFEEAGLPKGLLSVLVGKGSVVGDAIVKHPLVRKISFTGGTTTGRH-LAHIA 238
L L+LA+I+ EAG+P G+ +VL G G VG + +HP + KISFTGGT TG+ +A +
Sbjct 183 LTTLKLAEIYTEAGVPNGVFNVLTGSGREVGTWLTEHPRIEKISFTGGTDTGKKVMASAS 242
Query 239 ADKLITTSLELGGKSPTIVLPDADIELAAKGIAYGIFSSAGQACIAGSRLFIHSSIYDQF 298
A L ++ELGGKSP I+ DAD++ AA F S+GQ C G+R+F+ S + F
Sbjct 243 ASSLKDVTMELGGKSPLIICDDADLDRAADTAMMANFYSSGQVCTNGTRVFVPSHLKAAF 302
Query 299 LARLVEITKSLRVGHPEQKDVHMGSLINAAHLASVDRYVQLAKQEGGEILTGGQAMTEGE 358
A++VE +RVG+PE ++ + G L++ H+ SV Y+ K+EG +L GG+ +T+GE
Sbjct 303 EAKIVERVARIRVGNPEDENTNFGPLVSFPHMESVLGYIAKGKEEGARVLCGGERLTDGE 362
Query 359 FAKGSFYLPTIITGLKNQAQVCQEEIFGPVLVVMKYEHEDDLIEQANDSCFGLAAGIWTE 418
FAKG+F PT+ T + + +EEIFGPV+ ++ YE E+++I +AND+ FGLAAGI T
Sbjct 363 FAKGAFVAPTVFTDCTDDMTIVREEIFGPVMAILSYETEEEVIRRANDTDFGLAAGIVTR 422
Query 419 SYRKAWRIARVLEVGTVWINTYKKFSISAPFGGFKDSGIGREKGRQGILSYMQQKSIYMG 478
+A R+ LE G WIN + + P GG+K SG+GRE G + ++ + KS+ +
Sbjct 423 DLNRAHRVIHQLEAGICWINAWGESDAKMPVGGYKQSGVGRENGISSLNNFTRIKSVQVE 482
Query 479 LNE 481
L +
Sbjct 483 LGD 485
>B7V5R4 Betaine aldehyde dehydrogenase [Pseudomonas aeruginosa
(strain LESB58)]
Length=490
Score = 362 bits (928), Expect = 1e-123
Identities = 192/482 (40%), Positives = 292/482 (61%), Gaps = 6/482 (1%)
Query 3 KELYIAGEW-RLGRGKVIQSTFPADNSVNAEISTASFEDIEEAIVKADQAWRAPEWRNRL 61
++LYI G + G ++ PA+ V A++ AS ED+E A+ A + + W
Sbjct 7 QKLYIGGRYVEASSGATFETINPANGEVLAKVQRASREDVERAVQSAVEGQKV--WAAMT 64
Query 62 PHERAKILYKVADIIEARVDALAALQTRDNGKPLAETRGL-VFSAAATARYVAAACETMN 120
+R++IL + DI+ R D LAAL+T D GKPLAETR + + + A Y A +
Sbjct 65 AMQRSRILRRAVDILRERNDELAALETLDTGKPLAETRSVDIVTGADVLEYYAGLVPAIE 124
Query 121 DELTSQRAPDFMTFSVHEPVGVVAAITPWNSPIASEVQKLAPALAGGNAVILKPAEATSL 180
E R F+ ++ EP+GVVA I WN P+ + K APALA GNA+I KP+E T L
Sbjct 125 GEQIPLRETSFV-YTRREPLGVVAGIGAWNYPVQIALWKSAPALAAGNAMIFKPSEVTPL 183
Query 181 IALELAKIFEEAGLPKGLLSVLVGKGSVVGDAIVKHPLVRKISFTGGTTTGRH-LAHIAA 239
AL+LA+I+ EAG+P G+ +VL G G VG + +HPL+ KISFTGGT+TG+ +A ++
Sbjct 184 TALKLAEIYTEAGVPDGVFNVLTGSGREVGQWLTEHPLIEKISFTGGTSTGKKVMASASS 243
Query 240 DKLITTSLELGGKSPTIVLPDADIELAAKGIAYGIFSSAGQACIAGSRLFIHSSIYDQFL 299
L ++ELGGKSP I+ PDAD++ AA F S+GQ C G+R+FIH S +F
Sbjct 244 SSLKEVTMELGGKSPLIIFPDADLDRAADIAVMANFFSSGQVCTNGTRVFIHRSQQARFE 303
Query 300 ARLVEITKSLRVGHPEQKDVHMGSLINAAHLASVDRYVQLAKQEGGEILTGGQAMTEGEF 359
A+++E + +R+G P+ ++ + G L++ H+ SV Y++ K + +L GG+ +T+G F
Sbjct 304 AKVLERVQRIRLGDPQDENTNFGPLVSFPHMESVLGYIESGKAQKARLLCGGERVTDGAF 363
Query 360 AKGSFYLPTIITGLKNQAQVCQEEIFGPVLVVMKYEHEDDLIEQANDSCFGLAAGIWTES 419
KG++ PT+ T ++ + +EEIFGPV+ ++ Y+ ED+ I +AND+ +GLAAG+ T+
Sbjct 364 GKGAYVAPTVFTDCRDDMTIVREEIFGPVMSILVYDDEDEAIRRANDTEYGLAAGVVTQD 423
Query 420 YRKAWRIARVLEVGTVWINTYKKFSISAPFGGFKDSGIGREKGRQGILSYMQQKSIYMGL 479
+A R LE G WINT+ + P GG+K SG+GRE G + Y + KS+ + L
Sbjct 424 LARAHRAIHRLEAGICWINTWGESPAEMPVGGYKQSGVGRENGLTTLAHYTRIKSVQVEL 483
Query 480 NE 481
+
Sbjct 484 GD 485
>Q9HTJ1 NAD/NADP-dependent betaine aldehyde dehydrogenase [Pseudomonas
aeruginosa (strain ATCC 15692 / DSM 22644 / CIP 104116
/ JCM 14847 / LMG 12228 / 1C / PRS 101 / PAO1)]
Length=490
Score = 362 bits (928), Expect = 1e-123
Identities = 192/482 (40%), Positives = 292/482 (61%), Gaps = 6/482 (1%)
Query 3 KELYIAGEW-RLGRGKVIQSTFPADNSVNAEISTASFEDIEEAIVKADQAWRAPEWRNRL 61
++LYI G + G ++ PA+ V A++ AS ED+E A+ A + + W
Sbjct 7 QKLYIGGRYVEASSGATFETINPANGEVLAKVQRASREDVERAVQSAVEGQKV--WAAMT 64
Query 62 PHERAKILYKVADIIEARVDALAALQTRDNGKPLAETRGL-VFSAAATARYVAAACETMN 120
+R++IL + DI+ R D LAAL+T D GKPLAETR + + + A Y A +
Sbjct 65 AMQRSRILRRAVDILRERNDELAALETLDTGKPLAETRSVDIVTGADVLEYYAGLVPAIE 124
Query 121 DELTSQRAPDFMTFSVHEPVGVVAAITPWNSPIASEVQKLAPALAGGNAVILKPAEATSL 180
E R F+ ++ EP+GVVA I WN P+ + K APALA GNA+I KP+E T L
Sbjct 125 GEQIPLRETSFV-YTRREPLGVVAGIGAWNYPVQIALWKSAPALAAGNAMIFKPSEVTPL 183
Query 181 IALELAKIFEEAGLPKGLLSVLVGKGSVVGDAIVKHPLVRKISFTGGTTTGRH-LAHIAA 239
AL+LA+I+ EAG+P G+ +VL G G VG + +HPL+ KISFTGGT+TG+ +A ++
Sbjct 184 TALKLAEIYTEAGVPDGVFNVLTGSGREVGQWLTEHPLIEKISFTGGTSTGKKVMASASS 243
Query 240 DKLITTSLELGGKSPTIVLPDADIELAAKGIAYGIFSSAGQACIAGSRLFIHSSIYDQFL 299
L ++ELGGKSP I+ PDAD++ AA F S+GQ C G+R+FIH S +F
Sbjct 244 SSLKEVTMELGGKSPLIIFPDADLDRAADIAVMANFFSSGQVCTNGTRVFIHRSQQARFE 303
Query 300 ARLVEITKSLRVGHPEQKDVHMGSLINAAHLASVDRYVQLAKQEGGEILTGGQAMTEGEF 359
A+++E + +R+G P+ ++ + G L++ H+ SV Y++ K + +L GG+ +T+G F
Sbjct 304 AKVLERVQRIRLGDPQDENTNFGPLVSFPHMESVLGYIESGKAQKARLLCGGERVTDGAF 363
Query 360 AKGSFYLPTIITGLKNQAQVCQEEIFGPVLVVMKYEHEDDLIEQANDSCFGLAAGIWTES 419
KG++ PT+ T ++ + +EEIFGPV+ ++ Y+ ED+ I +AND+ +GLAAG+ T+
Sbjct 364 GKGAYVAPTVFTDCRDDMTIVREEIFGPVMSILVYDDEDEAIRRANDTEYGLAAGVVTQD 423
Query 420 YRKAWRIARVLEVGTVWINTYKKFSISAPFGGFKDSGIGREKGRQGILSYMQQKSIYMGL 479
+A R LE G WINT+ + P GG+K SG+GRE G + Y + KS+ + L
Sbjct 424 LARAHRAIHRLEAGICWINTWGESPAEMPVGGYKQSGVGRENGLTTLAHYTRIKSVQVEL 483
Query 480 NE 481
+
Sbjct 484 GD 485
>P71016 Betaine aldehyde dehydrogenase [Bacillus subtilis (strain
168)]
Length=490
Score = 360 bits (925), Expect = 3e-123
Identities = 187/487 (38%), Positives = 285/487 (59%), Gaps = 1/487 (0%)
Query 1 MVKELYIAGEWRLGRGKVIQSTF-PADNSVNAEISTASFEDIEEAIVKADQAWRAPEWRN 59
M + L+I GEW + I+S P + A +S ED +AI A +A+ EW +
Sbjct 1 MSQTLFIDGEWISAEKEQIRSIINPFNQEEIATVSEGGREDAIKAIAAARRAFDKGEWSS 60
Query 60 RLPHERAKILYKVADIIEARVDALAALQTRDNGKPLAETRGLVFSAAATARYVAAACETM 119
ER KI+ K+A++I ++ LA L++ D GK L E++ + A +Y A +
Sbjct 61 LSGLERGKIVLKIAELIRRDLEELAELESLDTGKTLEESKADMDDIANVFQYYAGLADKD 120
Query 120 NDELTSQRAPDFMTFSVHEPVGVVAAITPWNSPIASEVQKLAPALAGGNAVILKPAEATS 179
E+ S PD + + EP+GV ITPWN P+ K+APALA GN +++KP+E T
Sbjct 121 GGEIISSPIPDSESKIIREPIGVCGQITPWNYPLLQASWKIAPALAAGNTIVMKPSEITP 180
Query 180 LIALELAKIFEEAGLPKGLLSVLVGKGSVVGDAIVKHPLVRKISFTGGTTTGRHLAHIAA 239
L +++ K+ EEAG+PKG+ ++++G G+ VGD + + V ISFTGG TG+ + A+
Sbjct 181 LTTIKVFKLMEEAGVPKGVANLVLGPGATVGDELAVNKDVDLISFTGGIETGKKIMRAAS 240
Query 240 DKLITTSLELGGKSPTIVLPDADIELAAKGIAYGIFSSAGQACIAGSRLFIHSSIYDQFL 299
+ +LELGGK+P IV DAD+E+A +F AGQ C AGSRL + +I+DQFL
Sbjct 241 GNVKKIALELGGKNPNIVFKDADLEVAVDQALNAVFFHAGQVCSAGSRLLVEDAIHDQFL 300
Query 300 ARLVEITKSLRVGHPEQKDVHMGSLINAAHLASVDRYVQLAKQEGGEILTGGQAMTEGEF 359
A LV+ K +++G+ + G LI+A H A V++YV++ +EG ++ TGG+ + E
Sbjct 301 AELVKRAKRIKLGNGFHAETESGPLISAEHRAKVEKYVEIGIEEGAKLETGGKRPEDPEL 360
Query 360 AKGSFYLPTIITGLKNQAQVCQEEIFGPVLVVMKYEHEDDLIEQANDSCFGLAAGIWTES 419
G FY PTI + + ++ QEE+FGPVL V + E+++IE AND+ +GLA +W++
Sbjct 361 QNGFFYEPTIFSNCNSDMRIVQEEVFGPVLTVETFSSEEEVIELANDTIYGLAGAVWSKD 420
Query 420 YRKAWRIARVLEVGTVWINTYKKFSISAPFGGFKDSGIGREKGRQGILSYMQQKSIYMGL 479
K R+A L +GTVWIN + + AP+GG+K SG GRE G+ G+ Y + K +Y
Sbjct 421 IEKCERVAARLRMGTVWINDFHPYFAQAPWGGYKQSGFGRELGKIGLEEYTEVKHVYRNT 480
Query 480 NEQPNPW 486
W
Sbjct 481 KPAAVNW 487
>A4VKC2 Betaine aldehyde dehydrogenase [Stutzerimonas stutzeri
(strain A1501)]
Length=490
Score = 360 bits (925), Expect = 3e-123
Identities = 201/482 (42%), Positives = 286/482 (59%), Gaps = 6/482 (1%)
Query 3 KELYIAGEW-RLGRGKVIQSTFPADNSVNAEISTASFEDIEEAIVKADQAWRAPEWRNRL 61
++LYI G + + +S PA+ V AE++ A D+E A+ A+Q R W
Sbjct 7 QQLYIHGAYVDASSNQTFESINPANGEVLAEVAEAGAADLERAVESAEQGQRI--WAALT 64
Query 62 PHERAKILYKVADIIEARVDALAALQTRDNGKPLAETRGL-VFSAAATARYVAAACETMN 120
ERA+I+ + D++ R D LA L+T D GKPL+ETR + + + A Y A +
Sbjct 65 GIERARIMRRAVDLLRERNDELALLETLDTGKPLSETRSVDIITGADVLEYYAGLAPAIE 124
Query 121 DELTSQRAPDFMTFSVHEPVGVVAAITPWNSPIASEVQKLAPALAGGNAVILKPAEATSL 180
E R F+ ++ EP+GVVA I WN PI + K APALA GNA+I KP+E T L
Sbjct 125 GEQIPLRDSSFV-YTRREPLGVVAGIGAWNYPIQIALWKAAPALAAGNAMIFKPSEVTPL 183
Query 181 IALELAKIFEEAGLPKGLLSVLVGKGSVVGDAIVKHPLVRKISFTGGTTTGRH-LAHIAA 239
AL LA+IF EAGLP G+ +VL G G+ VG I +HP + K+SFTGG TG+ +A A
Sbjct 184 SALRLAEIFSEAGLPDGVFNVLTGSGAGVGALITEHPRIAKVSFTGGVATGKKVMASAAG 243
Query 240 DKLITTSLELGGKSPTIVLPDADIELAAKGIAYGIFSSAGQACIAGSRLFIHSSIYDQFL 299
L ++ELGGKSP IV DAD++ AA F S+GQ C G+R+FI + + F
Sbjct 244 SSLKDVTMELGGKSPLIVCEDADLDRAADIAVMANFFSSGQVCTNGTRVFIPAGLKASFE 303
Query 300 ARLVEITKSLRVGHPEQKDVHMGSLINAAHLASVDRYVQLAKQEGGEILTGGQAMTEGEF 359
A+L+E + +R+G P+Q+ + G L++ AH+ V Y+ K G IL GG+ +TEGE+
Sbjct 304 AKLLERVQRVRLGDPQQEATNFGPLVSFAHMDKVLDYIAQGKAAGARILCGGERVTEGEY 363
Query 360 AKGSFYLPTIITGLKNQAQVCQEEIFGPVLVVMKYEHEDDLIEQANDSCFGLAAGIWTES 419
A+G+F PTI + + + +EEIFGPVL +++Y+ ED+ I +AND+ +GLAAG+ T
Sbjct 364 ARGAFVAPTIFSDCSDDMSIVREEIFGPVLSLLEYQGEDEAIRRANDTEYGLAAGVVTPD 423
Query 420 YRKAWRIARVLEVGTVWINTYKKFSISAPFGGFKDSGIGREKGRQGILSYMQQKSIYMGL 479
+A RI LE G WINT+ + P GG+K SGIGRE G + Y + KS+ + L
Sbjct 424 LARAHRIIHRLEAGICWINTWGESPAQMPVGGYKQSGIGRENGIASLAHYTRVKSVQVEL 483
Query 480 NE 481
E
Sbjct 484 GE 485
>A6ZR27 Aldehyde dehydrogenase 5, mitochondrial [Saccharomyces
cerevisiae (strain YJM789)]
Length=520
Score = 361 bits (927), Expect = 3e-123
Identities = 196/484 (40%), Positives = 295/484 (61%), Gaps = 19/484 (4%)
Query 5 LYIAGEWRLGRGKVIQSTFPADNSVNAEISTASF----EDIEEAIVKADQAWRAPEWRNR 60
L+I GE+ + K TF N N E T + +D++EA+ A +A+ +W
Sbjct 46 LFINGEFVASKQK---KTFDVINPSNEEKITTVYKAMEDDVDEAVAAAKKAFET-KWSIV 101
Query 61 LPHERAKILYKVADIIEARVDALAALQTRDNGKPLAETRGLVFSAAATARYVAAACETMN 120
P RAK L+ +AD++E + LAA+++ DNGK L RG V A ++Y+ + C
Sbjct 102 EPEVRAKALFNLADLVEKHQETLAAIESMDNGKSLFCARGDV---ALVSKYLRS-CGGWA 157
Query 121 DELTSQ---RAPDFMTFSVHEPVGVVAAITPWNSPIASEVQKLAPALAGGNAVILKPAEA 177
D++ + T+S+ EP+GV I PWN P+ K+ PALA GN V+LKPAE
Sbjct 158 DKIYGNVIDTGKNHFTYSIKEPLGVCGQIIPWNFPLLMWSWKIGPALATGNTVVLKPAET 217
Query 178 TSLIALELAKIFEEAGLPKGLLSVLVGKGSVVGDAIVKHPLVRKISFTGGTTTGRHLAHI 237
T L AL +++ +EAG+P G++++L G G VVG+ + HP V+KI+FTG T TGRH+ +
Sbjct 218 TPLSALFASQLCQEAGIPAGVVNILPGSGRVVGERLSAHPDVKKIAFTGSTATGRHIMKV 277
Query 238 AADKLITTSLELGGKSPTIVLPDADIELAAKGIAYGIFSSAGQACIAGSRLFIHSSIYDQ 297
AAD + +LELGGKSP IV DAD++ A K IA+GIF ++G+ C AGSR++I ++Y++
Sbjct 278 AADTVKKVTLELGGKSPNIVFADADLDKAVKNIAFGIFYNSGEVCCAGSRIYIQDTVYEE 337
Query 298 FLARLVEITKSLRVGHPEQKDVHMGSLINAAHLASVDRYVQLAKQEGGEILTGGQAMTEG 357
L +L + T+SL+VG P ++V G+ + L + YV +AK EG ++TGG
Sbjct 338 VLQKLKDYTESLKVGDPFDEEVFQGAQTSDKQLHKILDYVDVAKSEGARLVTGGAR---- 393
Query 358 EFAKGSFYLPTIITGLKNQAQVCQEEIFGPVLVVMKYEHEDDLIEQANDSCFGLAAGIWT 417
+KG F PT+ +K ++ +EE+FGP++ V K+ D++I ANDS +GLAAGI T
Sbjct 394 HGSKGYFVKPTVFADVKEDMRIVKEEVFGPIVTVSKFSTVDEVIAMANDSQYGLAAGIHT 453
Query 418 ESYRKAWRIARVLEVGTVWINTYKKFSISAPFGGFKDSGIGREKGRQGILSYMQQKSIYM 477
KA +++ ++ GTVWINTY F + PFGGF SGIGRE G + +Y Q KS+ +
Sbjct 454 NDINKAVDVSKRVKAGTVWINTYNNFHQNVPFGGFGQSGIGREMGEAALSNYTQTKSVRI 513
Query 478 GLNE 481
+++
Sbjct 514 AIDK 517
>P40047 Aldehyde dehydrogenase 5, mitochondrial [Saccharomyces
cerevisiae (strain ATCC 204508 / S288c)]
Length=520
Score = 361 bits (927), Expect = 3e-123
Identities = 196/484 (40%), Positives = 295/484 (61%), Gaps = 19/484 (4%)
Query 5 LYIAGEWRLGRGKVIQSTFPADNSVNAEISTASF----EDIEEAIVKADQAWRAPEWRNR 60
L+I GE+ + K TF N N E T + +D++EA+ A +A+ +W
Sbjct 46 LFINGEFVASKQK---KTFDVINPSNEEKITTVYKAMEDDVDEAVAAAKKAFET-KWSIV 101
Query 61 LPHERAKILYKVADIIEARVDALAALQTRDNGKPLAETRGLVFSAAATARYVAAACETMN 120
P RAK L+ +AD++E + LAA+++ DNGK L RG V A ++Y+ + C
Sbjct 102 EPEVRAKALFNLADLVEKHQETLAAIESMDNGKSLFCARGDV---ALVSKYLRS-CGGWA 157
Query 121 DELTSQ---RAPDFMTFSVHEPVGVVAAITPWNSPIASEVQKLAPALAGGNAVILKPAEA 177
D++ + T+S+ EP+GV I PWN P+ K+ PALA GN V+LKPAE
Sbjct 158 DKIYGNVIDTGKNHFTYSIKEPLGVCGQIIPWNFPLLMWSWKIGPALATGNTVVLKPAET 217
Query 178 TSLIALELAKIFEEAGLPKGLLSVLVGKGSVVGDAIVKHPLVRKISFTGGTTTGRHLAHI 237
T L AL +++ +EAG+P G++++L G G VVG+ + HP V+KI+FTG T TGRH+ +
Sbjct 218 TPLSALFASQLCQEAGIPAGVVNILPGSGRVVGERLSAHPDVKKIAFTGSTATGRHIMKV 277
Query 238 AADKLITTSLELGGKSPTIVLPDADIELAAKGIAYGIFSSAGQACIAGSRLFIHSSIYDQ 297
AAD + +LELGGKSP IV DAD++ A K IA+GIF ++G+ C AGSR++I ++Y++
Sbjct 278 AADTVKKVTLELGGKSPNIVFADADLDKAVKNIAFGIFYNSGEVCCAGSRIYIQDTVYEE 337
Query 298 FLARLVEITKSLRVGHPEQKDVHMGSLINAAHLASVDRYVQLAKQEGGEILTGGQAMTEG 357
L +L + T+SL+VG P ++V G+ + L + YV +AK EG ++TGG
Sbjct 338 VLQKLKDYTESLKVGDPFDEEVFQGAQTSDKQLHKILDYVDVAKSEGARLVTGGAR---- 393
Query 358 EFAKGSFYLPTIITGLKNQAQVCQEEIFGPVLVVMKYEHEDDLIEQANDSCFGLAAGIWT 417
+KG F PT+ +K ++ +EE+FGP++ V K+ D++I ANDS +GLAAGI T
Sbjct 394 HGSKGYFVKPTVFADVKEDMRIVKEEVFGPIVTVSKFSTVDEVIAMANDSQYGLAAGIHT 453
Query 418 ESYRKAWRIARVLEVGTVWINTYKKFSISAPFGGFKDSGIGREKGRQGILSYMQQKSIYM 477
KA +++ ++ GTVWINTY F + PFGGF SGIGRE G + +Y Q KS+ +
Sbjct 454 NDINKAVDVSKRVKAGTVWINTYNNFHQNVPFGGFGQSGIGREMGEAALSNYTQTKSVRI 513
Query 478 GLNE 481
+++
Sbjct 514 AIDK 517
>A6VEI4 Betaine aldehyde dehydrogenase [Pseudomonas aeruginosa
(strain PA7)]
Length=490
Score = 359 bits (922), Expect = 8e-123
Identities = 191/482 (40%), Positives = 290/482 (60%), Gaps = 6/482 (1%)
Query 3 KELYIAGEW-RLGRGKVIQSTFPADNSVNAEISTASFEDIEEAIVKADQAWRAPEWRNRL 61
++LYI G + G ++ PA+ V A++ AS ED+E A+ A + + W
Sbjct 7 QKLYIGGRYVEASSGATFETINPANGEVLAKVQRASREDVERAVQSAVEGQKV--WAAMT 64
Query 62 PHERAKILYKVADIIEARVDALAALQTRDNGKPLAETRGL-VFSAAATARYVAAACETMN 120
+R++IL + D++ R D LAAL+T D GKPLAETR + + + A Y A +
Sbjct 65 AMQRSRILRRAVDLLRERNDELAALETLDTGKPLAETRAVDIVTGADVLEYYAGLVPAIE 124
Query 121 DELTSQRAPDFMTFSVHEPVGVVAAITPWNSPIASEVQKLAPALAGGNAVILKPAEATSL 180
E R F+ ++ EP+GVVA I WN P+ + K APALA GNA+I KP+E T L
Sbjct 125 GEQIPLRETSFV-YTRREPLGVVAGIGAWNYPVQIALWKSAPALAAGNAMIFKPSEVTPL 183
Query 181 IALELAKIFEEAGLPKGLLSVLVGKGSVVGDAIVKHPLVRKISFTGGTTTGRH-LAHIAA 239
AL+LA+I+ EAG+P G+ +VL G G VG + +HPL+ KISFTGGT+TG+ +A ++
Sbjct 184 TALKLAEIYTEAGVPDGVFNVLTGSGREVGQWLTEHPLIEKISFTGGTSTGKKVMASASS 243
Query 240 DKLITTSLELGGKSPTIVLPDADIELAAKGIAYGIFSSAGQACIAGSRLFIHSSIYDQFL 299
L ++ELGGKSP I+ PDAD++ AA F S+GQ C G+R+FIH S +F
Sbjct 244 SSLKEVTMELGGKSPLIIFPDADLDRAADIAVMANFFSSGQVCTNGTRVFIHRSQQARFE 303
Query 300 ARLVEITKSLRVGHPEQKDVHMGSLINAAHLASVDRYVQLAKQEGGEILTGGQAMTEGEF 359
A+++E + +R+G P+ ++ + G L++ H+ SV Y++ K + +L GG+ +TEG F
Sbjct 304 AKVLERVQRIRLGDPQDENTNFGPLVSFPHMESVLGYIESGKAQKARLLCGGERVTEGAF 363
Query 360 AKGSFYLPTIITGLKNQAQVCQEEIFGPVLVVMKYEHEDDLIEQANDSCFGLAAGIWTES 419
G++ PT+ T + + +EEIFGPV+ ++ Y+ ED+ I +AND+ +GLAAG+ T+
Sbjct 364 GNGAYVAPTVFTDCSDDMTIVREEIFGPVMSILVYDDEDEAIRRANDTEYGLAAGVVTQD 423
Query 420 YRKAWRIARVLEVGTVWINTYKKFSISAPFGGFKDSGIGREKGRQGILSYMQQKSIYMGL 479
+A R LE G WINT+ + P GG+K SG+GRE G + Y + KS+ + L
Sbjct 424 LARAHRAIHRLEAGICWINTWGESPAEMPVGGYKQSGVGRENGLTTLAHYTRIKSVQVEL 483
Query 480 NE 481
+
Sbjct 484 GD 485
>Q4K4K8 Betaine aldehyde dehydrogenase [Pseudomonas fluorescens
(strain ATCC BAA-477 / NRRL B-23932 / Pf-5)]
Length=490
Score = 358 bits (919), Expect = 2e-122
Identities = 190/483 (39%), Positives = 291/483 (60%), Gaps = 6/483 (1%)
Query 2 VKELYIAGEWR-LGRGKVIQSTFPADNSVNAEISTASFEDIEEAIVKADQAWRAPEWRNR 60
+++LYI G + G + PA+ V A++ A+ ED+E A+V A++ + W
Sbjct 6 LQKLYIDGGYTDAGSDATFDAINPANGEVLAQVQRATKEDVERAVVSAEKGQKI--WAAM 63
Query 61 LPHERAKILYKVADIIEARVDALAALQTRDNGKPLAETRGL-VFSAAATARYVAAACETM 119
ER++IL + +I+ R D LAAL+T D GK +ET+ + + + A Y A +
Sbjct 64 TAMERSRILRRAVEILRERNDELAALETLDTGKAFSETKYVDIVTGADVLEYYAGLVPAI 123
Query 120 NDELTSQRAPDFMTFSVHEPVGVVAAITPWNSPIASEVQKLAPALAGGNAVILKPAEATS 179
E R F+ ++ EP+GVVA I WN PI + K APALA GNA+I KP+E TS
Sbjct 124 EGEQIPLRTTSFV-YTRREPLGVVAGIGAWNYPIQIALWKSAPALAAGNAMIFKPSEVTS 182
Query 180 LIALELAKIFEEAGLPKGLLSVLVGKGSVVGDAIVKHPLVRKISFTGGTTTGRH-LAHIA 238
L L+LA+I+ EAGLP G+ +VL G G VG + +HP + K+SFTGGT TG+ +A +
Sbjct 183 LTTLKLAEIYTEAGLPDGVFNVLTGSGREVGTWLTEHPRIEKVSFTGGTDTGKKVMASAS 242
Query 239 ADKLITTSLELGGKSPTIVLPDADIELAAKGIAYGIFSSAGQACIAGSRLFIHSSIYDQF 298
+ L ++ELGGKSP I+ DAD++ AA F S+GQ C G+R+F+ S + F
Sbjct 243 SSSLKDVTMELGGKSPLIIFDDADLDRAADTAMMANFYSSGQVCTNGTRVFVPSHLKAAF 302
Query 299 LARLVEITKSLRVGHPEQKDVHMGSLINAAHLASVDRYVQLAKQEGGEILTGGQAMTEGE 358
A++ E +R+G+PE ++ + G L++ H+ SV Y+ K+EG +L GG+ +T+GE
Sbjct 303 EAKIAERVARIRIGNPEDENTNFGPLVSFPHMESVLGYIAKGKEEGARVLCGGERLTDGE 362
Query 359 FAKGSFYLPTIITGLKNQAQVCQEEIFGPVLVVMKYEHEDDLIEQANDSCFGLAAGIWTE 418
FAKG+F PT+ T + + +EEIFGPV+ ++ YE E+++I +AND+ FGLAAG+ T+
Sbjct 363 FAKGAFVAPTVFTDCTDDMTIVREEIFGPVMAILTYETEEEVIRRANDTDFGLAAGLVTK 422
Query 419 SYRKAWRIARVLEVGTVWINTYKKFSISAPFGGFKDSGIGREKGRQGILSYMQQKSIYMG 478
+A R+ LE G WIN + + P GG+K SG+GRE G + ++ + KS+ +
Sbjct 423 DLNRAHRVIHQLEAGICWINAWGESDAKMPVGGYKQSGVGRENGISSLNNFTRIKSVQVE 482
Query 479 LNE 481
L +
Sbjct 483 LGD 485
>Q2YV11 Putative aldehyde dehydrogenase AldA [Staphylococcus aureus
(strain bovine RF122 / ET3-1)]
Length=495
Score = 358 bits (918), Expect = 4e-122
Identities = 192/475 (40%), Positives = 289/475 (61%), Gaps = 6/475 (1%)
Query 5 LYIAGEWRLGRG-KVIQSTFPADNSVNAEISTASFEDIEEAIVKADQAWRAPEWRNRLPH 63
L+I GE+ G + I+ T PA + I+ A +D++ A+ A +A+ + W
Sbjct 15 LFINGEFVKGSSDETIEVTNPATGETLSHITRAKDKDVDHAVEVAQEAFES--WSLTSKS 72
Query 64 ERAKILYKVADIIEARVDALAALQTRDNGKPLAETRGL-VFSAAATARYVAAACETMNDE 122
ERA++L + D + A+ D +A ++T +NGKP+ ET + + AA Y A+ ET +
Sbjct 73 ERAQMLRDIGDKLMAQKDKIAMIETLNNGKPIRETTAIDIPFAARHFHYFASVIET-EEG 131
Query 123 LTSQRAPDFMTFSVHEPVGVVAAITPWNSPIASEVQKLAPALAGGNAVILKPAEATSLIA 182
+ D M+ HEP+GVV A+ WN P+ K+APA+A GN ++++P+ +T L
Sbjct 132 TVNDIDKDTMSIVRHEPIGVVGAVVAWNFPMLLAAWKIAPAIAAGNTIVIQPSSSTPLSL 191
Query 183 LELAKIFEEAGLPKGLLSVLVGKGSVVGDAIVKHPLVRKISFTGGTTTGRHLAHIAADKL 242
LE+AKIF+E LPKG++++L GKGS G+AI H V K+SFTG T G +A AA L
Sbjct 192 LEVAKIFQEV-LPKGVVNILTGKGSESGNAIFNHDGVDKLSFTGSTDVGYQVAEAAAKHL 250
Query 243 ITTSLELGGKSPTIVLPDADIELAAKGIAYGIFSSAGQACIAGSRLFIHSSIYDQFLARL 302
+ +LELGGKS I+L DA+++LA +GI GI + G+ C AGSRL +H IYDQ + RL
Sbjct 251 VPATLELGGKSANIILDDANLDLAVEGIQLGILFNQGEVCSAGSRLLVHEKIYDQLVPRL 310
Query 303 VEITKSLRVGHPEQKDVHMGSLINAAHLASVDRYVQLAKQEGGEILTGGQAMTEGEFAKG 362
E +++VG P+ + MGS L + Y+ +AK+ +IL GG +TE KG
Sbjct 311 QEAFSNIKVGDPQDEATQMGSQTGKDQLDKIQSYIDVAKESDAQILAGGHRLTENGLDKG 370
Query 363 SFYLPTIITGLKNQAQVCQEEIFGPVLVVMKYEHEDDLIEQANDSCFGLAAGIWTESYRK 422
F+ PT+I N ++ QEEIFGPVL V+K + + + I+ ANDS +GLA G+++++ +
Sbjct 371 FFFEPTLIAVPDNHHKLAQEEIFGPVLTVIKVKDDQEAIDIANDSKYGLAGGVFSQNITR 430
Query 423 AWRIARVLEVGTVWINTYKKFSISAPFGGFKDSGIGREKGRQGILSYMQQKSIYM 477
A IA+ + G +WINTY + APFGG+K SGIGRE + + +Y Q K+IY+
Sbjct 431 ALNIAKAVRTGRIWINTYNQVPEGAPFGGYKKSGIGRETYKGALSNYQQVKNIYI 485
>Q02DY9 Betaine aldehyde dehydrogenase [Pseudomonas aeruginosa
(strain UCBPP-PA14)]
Length=490
Score = 357 bits (917), Expect = 4e-122
Identities = 190/482 (39%), Positives = 289/482 (60%), Gaps = 6/482 (1%)
Query 3 KELYIAGEW-RLGRGKVIQSTFPADNSVNAEISTASFEDIEEAIVKADQAWRAPEWRNRL 61
++LYI G + G ++ PA+ V A++ AS ED+E A+ A + + W
Sbjct 7 QKLYIGGRYVEASSGATFETINPANGEVLAKVQRASREDVERAVQSAVEGQKV--WAAMT 64
Query 62 PHERAKILYKVADIIEARVDALAALQTRDNGKPLAETRGL-VFSAAATARYVAAACETMN 120
+R++IL + DI+ R D LAAL+T D GKPLAETR + + + A Y A +
Sbjct 65 AMQRSRILRRAVDILRERNDELAALETLDTGKPLAETRSVDIVTGADVLEYYAGLVPAIE 124
Query 121 DELTSQRAPDFMTFSVHEPVGVVAAITPWNSPIASEVQKLAPALAGGNAVILKPAEATSL 180
E R F+ ++ EP+GVVA I WN P+ + K APALA GNA+I KP+E T L
Sbjct 125 GEQIPLRETSFV-YTRREPLGVVAGIGAWNYPVQIALWKSAPALAAGNAMIFKPSEVTPL 183
Query 181 IALELAKIFEEAGLPKGLLSVLVGKGSVVGDAIVKHPLVRKISFTGGTTTGRH-LAHIAA 239
L+LA+I+ EAG+P G+ +VL G G VG + +HPL+ KISFTGGT+TG+ +A ++
Sbjct 184 TTLKLAEIYTEAGVPDGVFNVLTGSGREVGQWLTEHPLIEKISFTGGTSTGKKVMASASS 243
Query 240 DKLITTSLELGGKSPTIVLPDADIELAAKGIAYGIFSSAGQACIAGSRLFIHSSIYDQFL 299
L ++ELGGKSP I+ PDAD++ AA F S+GQ C G+R+FIH S +F
Sbjct 244 SSLKEVTMELGGKSPLIIFPDADLDRAADIAVMANFFSSGQVCTNGTRVFIHRSQQARFE 303
Query 300 ARLVEITKSLRVGHPEQKDVHMGSLINAAHLASVDRYVQLAKQEGGEILTGGQAMTEGEF 359
A+++E + +R+G P+ ++ + G L++ H+ SV Y++ K + +L GG+ +T+G F
Sbjct 304 AKVLERVQRIRLGDPQDENTNFGPLVSFPHMESVLGYIESGKAQKARLLCGGERVTDGAF 363
Query 360 AKGSFYLPTIITGLKNQAQVCQEEIFGPVLVVMKYEHEDDLIEQANDSCFGLAAGIWTES 419
G++ PT+ T + + +EEIFGPV+ ++ Y+ ED+ I +AND+ +GLAAG+ T+
Sbjct 364 GNGAYVAPTVFTDCSDDMTIVREEIFGPVMSILVYDDEDEAIRRANDTEYGLAAGVVTQD 423
Query 420 YRKAWRIARVLEVGTVWINTYKKFSISAPFGGFKDSGIGREKGRQGILSYMQQKSIYMGL 479
+A R LE G WINT+ + P GG+K SG+GRE G + Y + KS+ + L
Sbjct 424 LARAHRAIHRLEAGICWINTWGESPAEMPVGGYKQSGVGRENGLTTLAHYTRIKSVQVEL 483
Query 480 NE 481
+
Sbjct 484 GD 485
>O34660 Putative aldehyde dehydrogenase DhaS [Bacillus subtilis
(strain 168)]
Length=495
Score = 354 bits (908), Expect = 1e-120
Identities = 190/484 (39%), Positives = 283/484 (58%), Gaps = 13/484 (3%)
Query 3 KELYIAGEW-RLGRGKVIQSTFPADNSVNAEISTASFEDIEEAIVKADQAWRAPEWRNRL 61
K+LYI G++ G + PA + A D+++A+ A +A+ EWR
Sbjct 20 KKLYIDGKFVPSASGATFDTPNPATGETLMTLYEAQAADVDKAVKAARKAFDQGEWRTMS 79
Query 62 PHERAKILYKVADIIEARVDALAALQTRDNGKPLAET-RGLVFSAAATARYVAAACETMN 120
P R++++YK+AD++E LA L+T DNGKP+ ET G + A RY A C
Sbjct 80 PASRSRLMYKLADLMEEHKTELAQLETLDNGKPINETTNGDIPLAIEHMRYYAGWCT--- 136
Query 121 DELTSQRAP---DFMTFSVHEPVGVVAAITPWNSPIASEVQKLAPALAGGNAVILKPAEA 177
++T Q P + ++ HEPVGVV I PWN P+ + K+ ALA G ++LKPAE
Sbjct 137 -KITGQTIPVSGAYFNYTRHEPVGVVGQIIPWNFPLLMAMWKMGAALATGCTIVLKPAEQ 195
Query 178 TSLIALELAKIFEEAGLPKGLLSVLVGKGSVVGDAIVKHPLVRKISFTGGTTTGRHLAHI 237
T L AL LA++ ++AG P G+++++ G G G+A+ H V KI+FTG T G+ +
Sbjct 196 TPLSALYLAELIDQAGFPAGVINIIPGFGEDAGEALTNHEAVDKIAFTGSTEIGKKIMST 255
Query 238 AADKLITTSLELGGKSPTIVLPDADIELAAKGIAYGIFSSAGQACIAGSRLFIHSSIYDQ 297
AA + +LELGGKSP I+LPDA+++ A G G+ + GQ C AGSR+FIH YD+
Sbjct 256 AAKSIKRVTLELGGKSPNILLPDANLKKAIPGALNGVMFNQGQVCCAGSRVFIHKDQYDE 315
Query 298 FLARLVEITKSLRVGHPEQKDVHMGSLINAAHLASVDRYVQLAKQEGGEILTGGQAMTEG 357
+ + +SLR G KD +G L++ V Y+Q K EG + +TGG
Sbjct 316 VVDEMASYAESLRQGAGLHKDTQIGPLVSKEQHERVLSYIQKGKDEGAKAVTGGSC---- 371
Query 358 EFAKGSFYLPTIITGLKNQAQVCQEEIFGPVLVVMKYEHEDDLIEQANDSCFGLAAGIWT 417
F G F PT+ ++++ + +EEIFGPVL + YE D++IE+AN S +GLAAG+WT
Sbjct 372 PFEAGYFVAPTVFANVEDEMTIAKEEIFGPVLTAIPYETVDEVIERANHSEYGLAAGLWT 431
Query 418 ESYRKAWRIARVLEVGTVWINTYKKFSISAPFGGFKDSGIGREKGRQGILSYMQQKSIYM 477
E+ ++A IA L+ GTVW+N Y F ++PFGG+K SG+GRE G + +Y + KS+++
Sbjct 432 ENVKQAHYIADRLQAGTVWVNCYNVFDAASPFGGYKQSGLGREMGSYALDNYTEVKSVWV 491
Query 478 GLNE 481
L +
Sbjct 492 NLED 495
>O06837 Phenylacetaldehyde dehydrogenase [Pseudomonas fluorescens]
Length=502
Score = 344 bits (883), Expect = 8e-117
Identities = 195/480 (41%), Positives = 277/480 (58%), Gaps = 11/480 (2%)
Query 4 ELYIAGEWRLGRG-KVIQSTFPADNSVNAEISTASFEDIEEAIVKADQAWRAPEWRNRLP 62
++ I G+W + K + PA ++ ED+ A+ A ++ WR P
Sbjct 22 QMLIGGQWVNAQSDKTLNVYNPATGDTLTDVPDGDVEDVNAAVESAAATLQSDAWRRMPP 81
Query 63 HERAKILYKVADIIEARVDALAALQTRDNGKPLAETRGLVFSAAAT-ARYVAAACETMND 121
R +IL ++AD++EA D LA L+T +NGK L ++ + A+A RY+A +
Sbjct 82 SARERILLRLADLLEAHGDELARLETLNNGKLLIYSKMMEVGASAQWLRYMAGWATKLTG 141
Query 122 ---ELTSQRAPDFMTFSVHE--PVGVVAAITPWNSPIASEVQKLAPALAGGNAVILKPAE 176
+L+ PD + + + PVGVVAAI PWN P+ V K+APALA GN V+LKPAE
Sbjct 142 STLDLSLPLPPDVRSRASTQRVPVGVVAAIIPWNFPLLMAVWKIAPALACGNTVVLKPAE 201
Query 177 ATSLIALELAKIFEEAGLPKGLLSVLVGKGSVVGDAIVKHPLVRKISFTGGTTTGRHLAH 236
T L AL LA++ EAGLP G L+V+ G+G GDA+V+HP V K++FTG T GR +
Sbjct 202 ETPLTALRLAELAMEAGLPAGALNVVTGRGETAGDALVRHPKVAKVAFTGSTEVGRIIGS 261
Query 237 IAADKLITTSLELGGKSPTIVLPDADIELAAKGIAYGIFSSAGQACIAGSRLFIHSSIYD 296
L SLELGGKSP IVL D D + AA+G A IF + GQ C AGSRL++H SIY+
Sbjct 262 ACGRSLKAVSLELGGKSPVIVLADCDPQEAAEGAAAAIFFNHGQVCTAGSRLYVHESIYE 321
Query 297 QFLARLVEITKSLRVGHPEQKDVHMGSLINAAHLASVDRYVQLAKQEGGEILTGGQAMTE 356
+ RL I +S+ VG ++ VHMG +++ H +V R+++ ++G +++ GG TE
Sbjct 322 DVIQRLAVIGESIVVGSGLEQGVHMGPMVSKKHHENVLRHIRNGIEDGADLICGG---TE 378
Query 357 GEFAKGSFYLPTIITGL-KNQAQVCQEEIFGPVLVVMKYEHEDDLIEQANDSCFGLAAGI 415
A+G F PTI K ++ +E+FGPVLV + +++ +AN S +GL A I
Sbjct 379 APCAQGFFVKPTIFANREKKDIRLLSQEVFGPVLVATPFSDIAEVVNEANRSVYGLGASI 438
Query 416 WTESYRKAWRIARVLEVGTVWINTYKKFSISAPFGGFKDSGIGREKGRQGILSYMQQKSI 475
WT A RI LE GTVW+NT+ + PFGGFKDSG+GRE G I Y +S+
Sbjct 439 WTNDLSAALRINDELEAGTVWVNTHNMVDPNLPFGGFKDSGVGREHGAAAIEHYTTTRSL 498
>P46367 Potassium-activated aldehyde dehydrogenase, mitochondrial
[Saccharomyces cerevisiae (strain ATCC 204508 / S288c)]
Length=519
Score = 342 bits (878), Expect = 8e-116
Identities = 175/467 (37%), Positives = 277/467 (59%), Gaps = 5/467 (1%)
Query 15 RGKVIQSTFPADNSVNAEISTASFEDIEEAIVKADQAWRAPEWRNRLPHERAKILYKVAD 74
+ K + P+ I +D+EEA+ AD+A+ W P +R K LY++A+
Sbjct 58 QNKTFEVINPSTEEEICHIYEGREDDVEEAVQAADRAFSNGSWNGIDPIDRGKALYRLAE 117
Query 75 IIEARVDALAALQTRDNGKPLAETRGLVFSAAATARYVAAACETMNDELTSQRAPDFMTF 134
+IE D +A+++T DNGK ++ +RG V + A + ++ + F ++
Sbjct 118 LIEQDKDVIASIETLDNGKAISSSRGDVDLVINYLKSSAGFADKIDGRMIDTGRTHF-SY 176
Query 135 SVHEPVGVVAAITPWNSPIASEVQKLAPALAGGNAVILKPAEATSLIALELAKIFEEAGL 194
+ +P+GV I PWN P+ K+APAL GN V+LK AE+T L AL ++K +AG+
Sbjct 177 TKRQPLGVCGQIIPWNFPLLMWAWKIAPALVTGNTVVLKTAESTPLSALYVSKYIPQAGI 236
Query 195 PKGLLSVLVGKGSVVGDAIVKHPLVRKISFTGGTTTGRHLAHIAADKLITTSLELGGKSP 254
P G+++++ G G +VG+AI HP ++K++FTG T TGRH+ AA L +LELGGKSP
Sbjct 237 PPGVINIVSGFGKIVGEAITNHPKIKKVAFTGSTATGRHIYQSAAAGLKKVTLELGGKSP 296
Query 255 TIVLPDADIELAAKGIAYGIFSSAGQACIAGSRLFIHSSIYDQFLARLVEITKSLRVGHP 314
IV DA+++ A + I GI+ ++G+ C AGSR+++ SIYD+F+ ++S++VG P
Sbjct 297 NIVFADAELKKAVQNIILGIYYNSGEVCCAGSRVYVEESIYDKFIEEFKAASESIKVGDP 356
Query 315 EQKDVHMGSLINAAHLASVDRYVQLAKQEGGEILTGGQAMTEGEFAKGSFYLPTIITGLK 374
+ G+ + L + +YV + K EG ++TGG+ + +KG F PT+ +K
Sbjct 357 FDESTFQGAQTSQMQLNKILKYVDIGKNEGATLITGGERLG----SKGYFIKPTVFGDVK 412
Query 375 NQAQVCQEEIFGPVLVVMKYEHEDDLIEQANDSCFGLAAGIWTESYRKAWRIARVLEVGT 434
++ +EEIFGPV+ V K++ D++I ANDS +GLAAGI T + A ++A + GT
Sbjct 413 EDMRIVKEEIFGPVVTVTKFKSADEVINMANDSEYGLAAGIHTSNINTALKVADRVNAGT 472
Query 435 VWINTYKKFSISAPFGGFKDSGIGREKGRQGILSYMQQKSIYMGLNE 481
VWINTY F + PFGGF SG+GRE + +Y+Q K++ L+E
Sbjct 473 VWINTYNDFHHAVPFGGFNASGLGREMSVDALQNYLQVKAVRAKLDE 519
>Q6F9F7 (Z)-2-((N-methylformamido)methylene)-5-hydroxybutyrolactone
dehydrogenase [Acinetobacter baylyi (strain ATCC 33305
/ BD413 / ADP1)]
Length=488
Score = 332 bits (851), Expect = 3e-112
Identities = 184/482 (38%), Positives = 270/482 (56%), Gaps = 8/482 (2%)
Query 4 ELYIAGEWRLGRGKVIQSTFPADNSVNAEISTASFEDIEEAIVKADQAWRAPEWRNRLPH 63
+LYI G++ G + S PA + A++ A + + A+ A+QA+ W
Sbjct 5 QLYINGKFEDGAAQ-FDSINPATGEIWAKMPEARTDQVNRAVDAAEQAFYDSSWSGLTAS 63
Query 64 ERAKILYKVADIIEARVDALAALQTRDNGKPLAETRGLVFSAAATARYVAAACETMNDEL 123
+R K+LYK+AD++E LAAL+T D GK + ET + A RY A + +
Sbjct 64 QRGKLLYKLADLVEKSAPRLAALETTDTGKIIRETSSQIAYVAEYYRYYAGLADKIEGSF 123
Query 124 TSQRAPDFMTFSVHEPVGVVAAITPWNSPIASEVQKLAPALAGGNAVILKPAEATSLIAL 183
PD + V EPVGVVAAI PWNS + K+ PALA G V+LK +E L
Sbjct 124 IPVDKPDMQAWLVREPVGVVAAIVPWNSQLFLSAVKVGPALAAGCTVVLKASEEAPAPLL 183
Query 184 ELAKIFEEAGLPKGLLSVLVGKGSVVGDAIVKHPLVRKISFTGGTTTGRHLAHIAADKLI 243
E AK+ +EAG P G+++V+ G G G + HP V I+FTGG T +H+ +A+ L
Sbjct 184 EFAKLIDEAGFPAGVVNVITGFGPECGAVLSAHPKVAHIAFTGGPETAKHIVRNSAENLA 243
Query 244 TTSLELGGKSPTIVLPDADIELAAKGIAYGIFSSAGQACIAGSRLFIHSSIYDQFLARLV 303
SLELGGKSP IV D DI A IF++ GQ+C+AGSRL I SI D+FL RL
Sbjct 244 KVSLELGGKSPFIVFADTDINSALNAQIAAIFAATGQSCVAGSRLLIEESIKDEFLQRLA 303
Query 304 EITKSLRVGHPEQKDVHMGSLINAAHLASVDRYVQLAKQEGGEILTGGQAMTEGEFAKGS 363
E +S+++G P+ G L + + VQ + ++G +++TGGQ G
Sbjct 304 ERVQSIKMGLPDDMQTEYGPLCTLKQREKIQQVVQRSVEQGAKLITGGQVCD----GAGY 359
Query 364 FYLPTII--TGLKNQAQVCQEEIFGPVLVVMKYEHEDDLIEQANDSCFGLAAGIWTESYR 421
+Y PTI+ +G+ + AQ E+FGPVL V + E + I++AN + +GLA+G++T +
Sbjct 360 YYPPTILDCSGV-SDAQSIHTELFGPVLSVDTFSTEAEAIQKANSTPYGLASGVFTSNLT 418
Query 422 KAWRIARVLEVGTVWINTYKKFSISAPFGGFKDSGIGREKGRQGILSYMQQKSIYMGLNE 481
+A R+ R + G VW+NTY+ S APFGG+ SG GRE G L Y K++++ +++
Sbjct 419 RAHRMTRAIRSGIVWLNTYRVVSPLAPFGGYGLSGHGREGGLSAALEYTTTKTVWLRMSD 478
Query 482 QP 483
QP
Sbjct 479 QP 480
>P08157 Aldehyde dehydrogenase [Emericella nidulans (strain FGSC
A4 / ATCC 38163 / CBS 112.46 / NRRL 194 / M139)]
Length=497
Score = 332 bits (851), Expect = 4e-112
Identities = 181/479 (38%), Positives = 273/479 (57%), Gaps = 8/479 (2%)
Query 5 LYIAGEWRLG-RGKVIQSTFPADNSVNAEISTASFEDIEEAIVKADQAWRAPEWRNRLPH 63
L+I E+ G GK Q P++ V + A+ +D++ A+ A A+ P WR P
Sbjct 21 LFINNEFVKGVEGKTFQVINPSNEKVITSVHEATEKDVDVAVAAARAAFEGP-WRQVTPS 79
Query 64 ERAKILYKVADIIEARVDALAALQTRDNGKPLAETRGLVFSAAATARYVAAACETMNDEL 123
ER ++ K+AD++E +D LAA+++ DNGK + + ++ RY A + ++ +
Sbjct 80 ERGILINKLADLMERDIDTLAAIESLDNGKAFTMAKVDLANSIGCLRYYAGWADKIHGQ- 138
Query 124 TSQRAPDFMTFSVHEPVGVVAAITPWNSPIASEVQKLAPALAGGNAVILKPAEATSLIAL 183
T P+ +T++ HEPVGV I PWN P+ K+ PA+A GN V+LK AE T L AL
Sbjct 139 TIDTNPETLTYTRHEPVGVCGQIIPWNFPLLMWSWKIGPAVAAGNTVVLKTAEQTPLSAL 198
Query 184 ELAKIFEEAGLPKGLLSVLVGKGSVVGDAIVKHPLVRKISFTGGTTTGRHLAHIAA-DKL 242
AK+ +EAG P G+++V+ G G G AI H + K++FTG T GR + AA L
Sbjct 199 YAAKLIKEAGFPAGVINVISGFGRTAGAAISSHMDIDKVAFTGSTLVGRTILQAAAKSNL 258
Query 243 ITTSLELGGKSPTIVLPDADIELAAKGIAYGIFSSAGQACIAGSRLFIHSSIYDQFLARL 302
+LELGGKSP IV DADI+ A +GIF + GQ C AGSR+ + IYD+F+AR
Sbjct 259 KKVTLELGGKSPNIVFDDADIDNAISWANFGIFFNHGQCCCAGSRILVQEGIYDKFVARF 318
Query 303 VEITKSLRVGHPEQKDVHMGSLINAAHLASVDRYVQLAKQEGGEILTGGQAMTEGEFAKG 362
E + +VG+P ++D G ++ + Y+ K+ G + TGG +G
Sbjct 319 KERAQKNKVGNPFEQDTFQGPQVSQLQFDRIMEYINHGKKAGATVATGGDRHGN----EG 374
Query 363 SFYLPTIITGLKNQAQVCQEEIFGPVLVVMKYEHEDDLIEQANDSCFGLAAGIWTESYRK 422
F PT+ T + + ++ QEEIFGPV+ + K++ E + I+ N + +GLAA + T++
Sbjct 375 YFIQPTVFTDVTSDMKIAQEEIFGPVVTIQKFKDEAEAIKIGNSTDYGLAAAVHTKNVNT 434
Query 423 AWRIARVLEVGTVWINTYKKFSISAPFGGFKDSGIGREKGRQGILSYMQQKSIYMGLNE 481
A R++ L+ GTVWIN Y S APFGGFK SG+GRE G + +Y Q K+++ L +
Sbjct 435 AIRVSNALKAGTVWINNYNMISYQAPFGGFKQSGLGRELGSYALENYTQIKTVHYRLGD 493
>Q27640 Aldehyde dehydrogenase [Enchytraeus buchholzi]
Length=497
Score = 331 bits (848), Expect = 1e-111
Identities = 180/468 (38%), Positives = 273/468 (58%), Gaps = 14/468 (3%)
Query 16 GKVIQSTFPADNSVNAEISTASFEDIEEAIVKADQAW-RAPEWRNRLPHERAKILYKVAD 74
GK + P+ AE+ DI++A+ A A+ R E+R +R ++L+K+AD
Sbjct 32 GKTFATINPSTGEKLAEVQEGDKADIDKAVAAARAAFKRDAEYRKHDASDRGRLLFKLAD 91
Query 75 IIEARVDALAALQTRDNGKPLAETR-GLVFSAAATARYVAAACETMNDELTSQRAP---D 130
+IEA L L+T DNGKP A + G A RY A D++ Q P +
Sbjct 92 LIEAHRVQLRTLETLDNGKPFAMSYLGDTLMAQKVLRYYAGFA----DKIVGQTIPADGN 147
Query 131 FMTFSVHEPVGVVAAITPWNSPIASEVQKLAPALAGGNAVILKPAEATSLIALELAKIFE 190
++ HEPVGVV AITPWN P+ K+APA+A G ++LKPAE T L AL LA + +
Sbjct 148 VFCYTRHEPVGVVGAITPWNFPLHLAASKIAPAIAAGCTLVLKPAEQTPLTALYLASLVK 207
Query 191 EAGLPKGLLSVLVGKGSVVGDAIVKHPLVRKISFTGGTTTGRHLAHIAAD-KLITTSLEL 249
+AG P G+++++ G G G A+ HP + KI+FTG T G+ + + L +LEL
Sbjct 208 QAGFPAGVINIVPGLGHTAGAALTNHPDINKITFTGSTEVGQLIIQGSGKTNLKRVTLEL 267
Query 250 GGKSPTIVLPDADIELAAKGIAYGIFSSAGQACIAGSRLFIHSSIYDQFLARLVEITKSL 309
GGKSP I+ PD+D++ A + I ++ GQ C AGSR F+H IY++F+ R VE K
Sbjct 268 GGKSPNIIFPDSDLDYAVEVSHQAIMANMGQVCCAGSRTFVHEDIYEEFVRRSVERAKKR 327
Query 310 RVGHPEQKDVHMGSLINAAHLASVDRYVQLAKQEGGEILTGGQAMTEGEFAKGSFYLPTI 369
VG P G ++ L + ++ K EG ++ GG+ + + KG F PT+
Sbjct 328 TVGDPFDPKNENGPQVDETQLKKILELIESGKTEGAKLECGGKRLGD----KGYFVEPTV 383
Query 370 ITGLKNQAQVCQEEIFGPVLVVMKYEHEDDLIEQANDSCFGLAAGIWTESYRKAWRIARV 429
T + + +V +EEIFGPV ++ K++ D++IE+AND+ +GLAA ++T++ A ++A
Sbjct 384 FTDVTSSMRVAKEEIFGPVQLIFKFKDVDEVIERANDTSYGLAAAVFTKNIDTALKVANS 443
Query 430 LEVGTVWINTYKKFSISAPFGGFKDSGIGREKGRQGILSYMQQKSIYM 477
LE GTVW+NTY F+ APFGG+K SG GRE G G+ ++++ K++Y+
Sbjct 444 LEAGTVWVNTYNHFAFQAPFGGYKMSGQGREFGHYGLEAFLEVKTVYV 491
>P54115 Magnesium-activated aldehyde dehydrogenase, cytosolic
[Saccharomyces cerevisiae (strain ATCC 204508 / S288c)]
Length=500
Score = 331 bits (848), Expect = 1e-111
Identities = 180/466 (39%), Positives = 274/466 (59%), Gaps = 7/466 (2%)
Query 16 GKVIQSTFPADNSVNAEISTASFEDIEEAIVKADQAWRAPEWRNRLPHERAKILYKVADI 75
GK P+ + E+S+A+ ED+E AI AD+A+ EW + P ER ++L K+AD
Sbjct 40 GKTYPVEDPSTENTVCEVSSATTEDVEYAIECADRAFHDTEWATQDPRERGRLLSKLADE 99
Query 76 IEARVDALAALQTRDNGKPLAETRGLVFSAAATARYVAAACETMNDELTSQRAPDFMTFS 135
+E+++D +++++ DNGK LA RG V A R AA + +N T +M F+
Sbjct 100 LESQIDLVSSIEALDNGKTLALARGDVTIAINCLRDAAAYADKVNGR-TINTGDGYMNFT 158
Query 136 VHEPVGVVAAITPWNSPIASEVQKLAPALAGGNAVILKPAEATSLIALELAKIFEEAGLP 195
EP+GV I PWN PI K+APALA GN ILKPA T L AL A + ++ G+P
Sbjct 159 TLEPIGVCGQIIPWNFPIMMLAWKIAPALAMGNVCILKPAAVTPLNALYFASLCKKVGIP 218
Query 196 KGLLSVLVGKGSVVGDAIVKHPLVRKISFTGGTTTGRHLAHIAADK-LITTSLELGGKSP 254
G+++++ G G VG A+ P +RK++FTG T G+ +A +++ L +LELGGKS
Sbjct 219 AGVVNIVPGPGRTVGAALTNDPRIRKLAFTGSTEVGKSVAVDSSESNLKKITLELGGKSA 278
Query 255 TIVLPDADIELAAKGIAYGIFSSAGQACIAGSRLFIHSSIYDQFLARL-VEITKSLRVGH 313
+V DA+I+ + GIF +AGQ C +GSR+++ IYD+ LA + ++VG+
Sbjct 279 HLVFDDANIKKTLPNLVNGIFKNAGQICSSGSRIYVQEGIYDELLAAFKAYLETEIKVGN 338
Query 314 PEQKDVHMGSLINAAHLASVDRYVQLAKQEGGEILTGGQAMTEGEFAKGSFYLPTIITGL 373
P K G++ N ++ Y+ + K+EG +ILTGG+ + + KG F PT+ +
Sbjct 339 PFDKANFQGAITNRQQFDTIMNYIDIGKKEGAKILTGGEKVGD----KGYFIRPTVFYDV 394
Query 374 KNQAQVCQEEIFGPVLVVMKYEHEDDLIEQANDSCFGLAAGIWTESYRKAWRIARVLEVG 433
++ +EEIFGPV+ V K++ ++ +E AN S FGL +GI TES ++A++L+ G
Sbjct 395 NEDMRIVKEEIFGPVVTVAKFKTLEEGVEMANSSEFGLGSGIETESLSTGLKVAKMLKAG 454
Query 434 TVWINTYKKFSISAPFGGFKDSGIGREKGRQGILSYMQQKSIYMGL 479
TVWINTY F PFGG K SG GRE G + +Y + K++ + L
Sbjct 455 TVWINTYNDFDSRVPFGGVKQSGYGREMGEEVYHAYTEVKAVRIKL 500
Lambda K H a alpha
0.319 0.134 0.393 0.792 4.96
Gapped
Lambda K H a alpha sigma
0.267 0.0410 0.140 1.90 42.6 43.6
Effective search space used: 3661395
Database: 55dc12a402cc85bbbf917edd20a71488.SwissProt.fasta
Posted date: May 19, 2024 7:52 AM
Number of letters in database: 9,443
Number of sequences in database: 19
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Neighboring words threshold: 11
Window for multiple hits: 40
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Data ...
