BLASTP 2.12.0+
Reference: Stephen F. Altschul, Thomas L. Madden, Alejandro A.
Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J.
Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of
protein database search programs", Nucleic Acids Res. 25:3389-3402.
Reference for composition-based statistics: Alejandro A. Schaffer,
L. Aravind, Thomas L. Madden, Sergei Shavirin, John L. Spouge, Yuri
I. Wolf, Eugene V. Koonin, and Stephen F. Altschul (2001),
"Improving the accuracy of PSI-BLAST protein database searches with
composition-based statistics and other refinements", Nucleic Acids
Res. 29:2994-3005.
Database: 5bd86ce5af357871930e746f54c4a47f.SwissProt.fasta
16 sequences; 7,562 total letters
Query= ACIAD1020
Length=469
Score E
Sequences producing significant alignments: (Bits) Value
P50970 Dihydrolipoyl dehydrogenase [Zymomonas mobilis subsp. mobi... 500 1e-178
O05940 Dihydrolipoyl dehydrogenase [Rhizobium etli (strain CFN 42... 461 2e-163
P54533 Dihydrolipoyl dehydrogenase [Bacillus subtilis (strain 168)] 360 1e-123
Q8KCW2 Dihydrolipoyl dehydrogenase [Chlorobaculum tepidum (strain... 355 1e-121
O50311 Dihydrolipoyl dehydrogenase [Chlorobaculum parvum (strain ... 352 2e-120
P18925 Dihydrolipoyl dehydrogenase [Azotobacter vinelandii] 342 1e-116
P9WHH8 Dihydrolipoyl dehydrogenase [Mycobacterium tuberculosis (s... 335 3e-114
P66005 Dihydrolipoyl dehydrogenase [Mycobacterium bovis (strain A... 335 3e-114
P9WHH9 Dihydrolipoyl dehydrogenase [Mycobacterium tuberculosis (s... 335 3e-114
Q50068 Dihydrolipoyl dehydrogenase [Mycobacterium leprae (strain ... 334 1e-113
P14218 Dihydrolipoyl dehydrogenase [Pseudomonas fluorescens] 333 4e-113
Q9I3D1 Dihydrolipoyl dehydrogenase [Pseudomonas aeruginosa (strai... 333 5e-113
O34324 Dihydrolipoyl dehydrogenase [Bacillus subtilis (strain 168)] 325 4e-110
P52992 Dihydrolipoyl dehydrogenase [Cupriavidus necator (strain A... 325 6e-110
P31052 Dihydrolipoyl dehydrogenase [Pseudomonas putida] 320 5e-108
P31023 Dihydrolipoyl dehydrogenase, mitochondrial [Pisum sativum] 320 6e-108
>P50970 Dihydrolipoyl dehydrogenase [Zymomonas mobilis subsp.
mobilis (strain ATCC 31821 / ZM4 / CP4)]
Length=466
Score = 500 bits (1287), Expect = 1e-178
Identities = 246/461 (53%), Positives = 327/461 (71%), Gaps = 1/461 (0%)
Query 8 FDLVVIGAGPGGYVAAIRAAQLGLKTAIVEATHLGGICLNWGCIPTKALLAGAELAHQFK 67
FDL+V+G GPGGYVAAIRAAQL LK A+VE HLGGICLNWGCIPTK+LL AE+ H+ +
Sbjct 5 FDLIVLGGGPGGYVAAIRAAQLNLKVALVERVHLGGICLNWGCIPTKSLLRSAEVYHEMQ 64
Query 68 HASQFGFELGDINFDLSKLVQHSRQVSAQLVQGIEHLLRKNQVSVFYAKARFIAKERLEL 127
+A +G +FDL K++ SR+V+ +L G++ LLRKN+V V + +++ +
Sbjct 65 NAEAYGLTSFKPDFDLDKIIARSREVATRLASGVKTLLRKNKVEVISGVGQLTGNQQMLV 124
Query 128 VDAQQQKQMIRAPHIIVATGAHAASLPQIPVDGDYVWSYKEALQPKQLPKSLLVIGSGAI 187
+ +++++ A II+ATGA A LP + DG ++W+Y AL+P +PK LLVIGSGAI
Sbjct 125 ETTEGEEKILEAKDIIIATGARARQLPNVHSDGKHIWTYHHALKPPAMPKKLLVIGSGAI 184
Query 188 GSEFASLYQDLGSQVTLLDLARQILPTEDHEVAQYVRKQFEQKGMRILTESTVQHLEVCE 247
G EFAS Y D G++V++++ A QILP ED EV+ YV K F+++G+RILT+S +Q+L +
Sbjct 185 GIEFASFYADFGAEVSIVEHAPQILPMEDAEVSAYVAKAFKKRGIRILTQSALQNLTPDD 244
Query 248 GKVHCEIHDPSG-VQSLSFDHVLSAVGVKPNTQNLGLEQLGVALTNGFIQTDEWCRTNVV 306
V EI G V F H + A+GV N +N+GL++LG+ L GFI D + RTNV
Sbjct 245 EGVTAEIAGADGKVTKERFSHAIVAIGVVANVENIGLDKLGIKLDRGFIAVDGFGRTNVD 304
Query 307 GIYAIGDVAGAPCLAHKASHEAILCVEKIAGIADVHPLNRLQIPGCIFTHPQVASIGLTE 366
++AIGDVAGAPCLAHKASH+ ++ E IAG VHPLN IPGC + PQVAS+GLTE
Sbjct 305 HVWAIGDVAGAPCLAHKASHQGVIAAEAIAGCDHVHPLNTQNIPGCTYARPQVASVGLTE 364
Query 367 QQAKAEGKQIHIGKFPMSANGKAIALGQTAGFVKTIVDVESGELLGAHMVGHEVTEQIQG 426
++A+ +G + IG FP ANGKAIA G T GFVKT+ D +SG LLGAHMVG EVTE IQG
Sbjct 365 EKARQQGYNVKIGNFPFIANGKAIAQGATDGFVKTVFDADSGALLGAHMVGAEVTEMIQG 424
Query 427 YAIAQALEATDEHLAQVIFPHPTLSEAMHESILASMQRAIH 467
Y +A+ LE T+ + + IFPHPTLSEAMHES+LA+ RA+H
Sbjct 425 YTVARTLETTEAEIMETIFPHPTLSEAMHESVLAAYGRALH 465
>O05940 Dihydrolipoyl dehydrogenase [Rhizobium etli (strain CFN
42 / ATCC 51251)]
Length=481
Score = 461 bits (1187), Expect = 2e-163
Identities = 236/476 (50%), Positives = 320/476 (67%), Gaps = 16/476 (3%)
Query 8 FDLVVIGAGPGGYVAAIRAAQLGLKTAIVEATHLGGICLNWGCIPTKALLAGAELAHQFK 67
+D+++IG+GPGGYVAAIRA+QLGLKTAIVE H+GGICLNWGCIPTKALL AE+
Sbjct 5 YDVIIIGSGPGGYVAAIRASQLGLKTAIVEREHMGGICLNWGCIPTKALLRSAEVLDHAN 64
Query 68 HASQFGFEL-GDINFDLSKLVQHSRQVSAQLVQGIEHLLRKNQVSVFYAKARF------- 119
H FG L G + D +V SR VSA+L G+ L++KN++ + + +A+
Sbjct 65 HFKDFGLVLEGSVKPDAKAVVGRSRAVSARLNAGVGFLMKKNKIDIIWGEAKLTKPGEIV 124
Query 120 IAKERLELVDAQQQ-------KQMIRAPHIIVATGAHAASLPQIPVDGDYVWSYKEALQP 172
+ K +V+ Q + A HII+ATGA +LP I DG +W+Y EAL+P
Sbjct 125 VGKSSKPVVEPQHPLPKNVKGEGTYTAKHIIIATGARPRALPGIEPDGKLIWTYFEALKP 184
Query 173 KQLPKSLLVIGSGAIGSEFASLYQDLGSQVTLLDLARQILPTEDHEVAQYVRKQFEQKGM 232
LPKSL+V+GSGAIG EFAS Y+ +G VT++++ I+P ED E+ RKQ E++G+
Sbjct 185 DALPKSLIVMGSGAIGIEFASFYRSMGVDVTVVEVMPTIMPVEDAEITAIARKQLEKRGL 244
Query 233 RILTESTVQHLEVCEGKVHCEIHDPSG-VQSLSFDHVLSAVGVKPNTQNLGLEQLGVALT 291
+I T + V +E G + + G VQ ++ D ++SAVGV+ N +NLGLE LGV
Sbjct 245 KIFTSAKVTKVEKGAGSITAHVETSDGKVQQITADRMISAVGVQGNIENLGLEALGVKTD 304
Query 292 NGFIQTDEWCRTNVVGIYAIGDVAGAPCLAHKASHEAILCVEKIAGIADVHPLNRLQIPG 351
G + D + +TNV GIYAIGDVAG P LAHKA HE ++CVEKIAG+ +VHP ++ ++PG
Sbjct 305 RGCVVADGYGKTNVAGIYAIGDVAGPPMLAHKAEHEGVVCVEKIAGLPNVHPTDKGKVPG 364
Query 352 CIFTHPQVASIGLTEQQAKAEGKQIHIGKFPMSANGKAIALGQTAGFVKTIVDVESGELL 411
C + +PQVAS+GLTE +AK G+ I +G+F +ANGKAIALG+ G VK I D ++GELL
Sbjct 365 CTYCNPQVASVGLTEAKAKELGRDIRVGRFSFAANGKAIALGEDQGMVKVIFDKKTGELL 424
Query 412 GAHMVGHEVTEQIQGYAIAQALEATDEHLAQVIFPHPTLSEAMHESILASMQRAIH 467
GAHMVG EVTE IQG+ +A LE T+E L IFPHPT+SE M E++L + R ++
Sbjct 425 GAHMVGAEVTELIQGFVVAMNLETTEEELMHTIFPHPTVSETMKEAVLDAYGRVLN 480
>P54533 Dihydrolipoyl dehydrogenase [Bacillus subtilis (strain
168)]
Length=474
Score = 360 bits (924), Expect = 1e-123
Identities = 188/472 (40%), Positives = 287/472 (61%), Gaps = 11/472 (2%)
Query 6 TQFDLVVIGAGPGGYVAAIRAAQLGLKTAIVEATHLGGICLNWGCIPTKALLAGAELAHQ 65
T++D+V++G G GGYVAAIRAAQLGLKTA+VE LGG CL+ GCIP+KALL AE+
Sbjct 3 TEYDVVILGGGTGGYVAAIRAAQLGLKTAVVEKEKLGGTCLHKGCIPSKALLRSAEVYRT 62
Query 66 FKHASQFGFELGDINFDLSKLVQHSRQVSAQLVQGIEHLLRKNQVSVFYAKARFIAKERL 125
+ A QFG E ++ + K+ Q + V +L G+ HL++K ++ V+ R +
Sbjct 63 AREADQFGVETAGVSLNFEKVQQRKQAVVDKLAAGVNHLMKKGKIDVYTGYGRILGPSIF 122
Query 126 ELVDAQ--------QQKQMIRAPHIIVATGAHAASLPQIPVDGDYVWSYKEALQPKQLPK 177
+ ++ M+ +I+ATG+ LP + VDG V + EALQ ++LP+
Sbjct 123 SPLPGTISVERGNGEENDMLIPKQVIIATGSRPRMLPGLEVDGKSVLTSDEALQMEELPQ 182
Query 178 SLLVIGSGAIGSEFASLYQDLGSQVTLLDLARQILPTEDHEVAQYVRKQFEQKGMRILTE 237
S++++G G IG E+AS+ D G +VT+++ A +ILPTED E+++ + ++KG++ +T
Sbjct 183 SIIIVGGGVIGIEWASMLHDFGVKVTVIEYADRILPTEDLEISKEMESLLKKKGIQFITG 242
Query 238 STV--QHLEVCEGKVHCEIHDPSGVQSLSFDHVLSAVGVKPNTQNLGLEQLGVALTNGFI 295
+ V + + + + S + +L ++G + N + +GLE + NG I
Sbjct 243 AKVLPDTMTKTSDDISIQAEKDGETVTYSAEKMLVSIGRQANIEGIGLENTDIVTENGMI 302
Query 296 QTDEWCRTNVVGIYAIGDVAGAPCLAHKASHEAILCVEKIAGIADVHPLNRLQIPGCIFT 355
+E C+T IYAIGDV G LAH ASHE I+ VE AG+ + HPL+ +P CI++
Sbjct 303 SVNESCQTKESHIYAIGDVIGGLQLAHVASHEGIIAVEHFAGL-NPHPLDPTLVPKCIYS 361
Query 356 HPQVASIGLTEQQAKAEGKQIHIGKFPMSANGKAIALGQTAGFVKTIVDVESGELLGAHM 415
P+ AS+GLTE +AKA G + IGKFP A GKA+ G++ GFVK + D ++ ++LG HM
Sbjct 362 SPEAASVGLTEDEAKANGHNVKIGKFPFMAIGKALVYGESDGFVKIVADRDTDDILGVHM 421
Query 416 VGHEVTEQIQGYAIAQALEATDEHLAQVIFPHPTLSEAMHESILASMQRAIH 467
+G VT+ I +A+ L+AT + Q I PHPTLSEA+ E+ LA+ +AIH
Sbjct 422 IGPHVTDMISEAGLAKVLDATPWEVGQTIHPHPTLSEAIGEAALAADGKAIH 473
Score = 20.8 bits (42), Expect = 1.6
Identities = 8/37 (22%), Positives = 17/37 (46%), Gaps = 0/37 (0%)
Query 1 MSMSDTQFDLVVIGAGPGGYVAAIRAAQLGLKTAIVE 37
+ M + ++++G G G A G+K ++E
Sbjct 175 LQMEELPQSIIIVGGGVIGIEWASMLHDFGVKVTVIE 211
>Q8KCW2 Dihydrolipoyl dehydrogenase [Chlorobaculum tepidum (strain
ATCC 49652 / DSM 12025 / NBRC 103806 / TLS)]
Length=469
Score = 355 bits (910), Expect = 1e-121
Identities = 196/467 (42%), Positives = 286/467 (61%), Gaps = 5/467 (1%)
Query 1 MSMSDT---QFDLVVIGAGPGGYVAAIRAAQLGLKTAIVEATHLGGICLNWGCIPTKALL 57
M +DT QFD+ VIG+GPGGY AAI AA+ GLKT IVE LGG+C+NWGCIPTKALL
Sbjct 1 MQQADTLAAQFDVAVIGSGPGGYEAAIHAARYGLKTCIVEKAVLGGVCVNWGCIPTKALL 60
Query 58 AGAELAHQFKHASQFGFELGDINFDLSKLVQHSRQVSAQLVQGIEHLLRKNQVSVFYAKA 117
AE+ K+ FG +G+++FDL++ V+ SR V+ + +G+ +LL+K V V +A
Sbjct 61 RSAEVFDLAKNPETFGVNVGNVSFDLAQAVKRSRNVALKSSKGVAYLLKKAAVEVLAGEA 120
Query 118 RFIAKERLELVDAQQQKQMIRAPHIIVATGAHAASLPQIPVDGDYVWSYKEALQPKQLPK 177
+ + +M+ A +IIVATG+ +P + DG + + +EAL K++PK
Sbjct 121 VLTGGAGVMVTMPDGSVRMLGAKNIIVATGSTPRVIPGLEPDGKKIITSREALILKEVPK 180
Query 178 SLLVIGSGAIGSEFASLYQDLGSQVTLLDLARQILPTEDHEVAQYVRKQFEQKGMRILTE 237
S++V+G GAIG E A Y GS+VT+++L ++LP E+ EV++ +++ FE+ G+ +
Sbjct 181 SMIVVGGGAIGVEMAWFYAKAGSKVTIVELMPRMLPAEEAEVSEALKRSFEKAGITVHCG 240
Query 238 STVQHLEVCEGKVHCE-IHDPSGVQSLSFDHVLSAVGVKPNTQNLGLEQLGVALTNGFIQ 296
+ + ++ V E V E + + S Q+L+ +L AVGV LGL+ +GV GFI+
Sbjct 241 AKLDNVAVSESGVSAELVVEGSAPQTLNASCLLVAVGVTGAIDGLGLDAVGVETERGFIR 300
Query 297 TDEWCRTNVVGIYAIGDVAGAPCLAHKASHEAILCVEKIAGIADVHPLNRLQIPGCIFTH 356
TD CRT+ GIYAIGDV G LAHKAS EA + VE IAG PL+ IP C++
Sbjct 301 TDGQCRTSAPGIYAIGDVRGGMLLAHKASAEAAIAVEAIAG-KSPEPLSEPLIPRCVYAQ 359
Query 357 PQVASIGLTEQQAKAEGKQIHIGKFPMSANGKAIALGQTAGFVKTIVDVESGELLGAHMV 416
P VAS+GLTE+ A G Q+ +G+ +A+GKA A GQ GFVK + D +G++LG H++
Sbjct 360 PSVASVGLTEEAAVNAGYQVAVGRSQFAASGKANAYGQLEGFVKLVFDAATGKMLGGHLI 419
Query 417 GHEVTEQIQGYAIAQALEATDEHLAQVIFPHPTLSEAMHESILASMQ 463
GH+ E I +A T L + HPTLSE + E+ ++Q
Sbjct 420 GHDAVELIGELGLACRYGVTAGGLVNTVHAHPTLSETVREAAFDALQ 466
>O50311 Dihydrolipoyl dehydrogenase [Chlorobaculum parvum (strain
DSM 263 / NCIMB 8327)]
Length=469
Score = 352 bits (902), Expect = 2e-120
Identities = 186/461 (40%), Positives = 288/461 (62%), Gaps = 2/461 (0%)
Query 4 SDTQFDLVVIGAGPGGYVAAIRAAQLGLKTAIVEATHLGGICLNWGCIPTKALLAGAELA 63
S QFD+ VIG+GPGGY AA+ AA+ G+K +VE LGG+C+NWGCIPTKALL AE+
Sbjct 7 SSAQFDVAVIGSGPGGYEAALHAARHGMKVCLVEKASLGGVCVNWGCIPTKALLRSAEVY 66
Query 64 HQFKHASQFGFELGDINFDLSKLVQHSRQVSAQLVQGIEHLLRKNQVSVFYAKARFIAKE 123
K+ S+FG + +++FDL++ V+ SR+VS + +G+E +L+K +V V+ +A +
Sbjct 67 DLAKNPSEFGVNVSELSFDLAQAVKRSRKVSLKSSKGVEFMLKKAKVEVWRGEAVLTGSK 126
Query 124 RLELVDAQQQKQMIRAPHIIVATGAHAASLPQIPVDGDYVWSYKEALQPKQLPKSLLVIG 183
+++ ++ + A +IIVATGA +P + DG + + +EAL K +P+S++V+G
Sbjct 127 GVKVTAEDGSERSLEAANIIVATGAQPRVIPGLEPDGKKIITSREALILKDVPESMIVVG 186
Query 184 SGAIGSEFASLYQDLGSQVTLLDLARQILPTEDHEVAQYVRKQFEQKGMRILTESTVQHL 243
GAIG E A Y G++VT+++L ++LP E+ EV++ +++ FE+ + + + + ++
Sbjct 187 GGAIGVEMAWFYAKAGAKVTIVELMPRLLPAEEAEVSEALKRSFEKVDITVQCGAKLGNV 246
Query 244 EVCEGKVHCE-IHDPSGVQSLSFDHVLSAVGVKPNTQNLGLEQLGVALTNGFIQTDEWCR 302
+ E V+ + + + Q + +L AVGV LGL+ G+ GFI+TDE CR
Sbjct 247 AISEFGVNADLLAEGKEPQKIEASCMLVAVGVTGVIDGLGLDAAGIETERGFIRTDELCR 306
Query 303 TNVVGIYAIGDVAGAPCLAHKASHEAILCVEKIAGIADVHPLNRLQIPGCIFTHPQVASI 362
T+ GIYAIGDV G LAHKAS EA + VE IAG PL+ IP C++ P VAS+
Sbjct 307 TSASGIYAIGDVRGGMLLAHKASAEAAIAVEAIAGKLP-EPLSEPLIPRCVYAQPSVASV 365
Query 363 GLTEQQAKAEGKQIHIGKFPMSANGKAIALGQTAGFVKTIVDVESGELLGAHMVGHEVTE 422
GLTE+ A A G ++ +G+ +A+GKA A GQ GFVK + + E+G++LG H++GH+ E
Sbjct 366 GLTEEAAIAAGYKVLVGRSQFAASGKANAYGQLEGFVKLVFNAETGKMLGGHLIGHDAVE 425
Query 423 QIQGYAIAQALEATDEHLAQVIFPHPTLSEAMHESILASMQ 463
I +A T E L + HPTLSE + E+ A++Q
Sbjct 426 LIGELGLACRYGVTAEGLVGTVHAHPTLSETVREAAFAALQ 466
Score = 23.1 bits (48), Expect = 0.30
Identities = 12/35 (34%), Positives = 17/35 (49%), Gaps = 0/35 (0%)
Query 3 MSDTQFDLVVIGAGPGGYVAAIRAAQLGLKTAIVE 37
+ D ++V+G G G A A+ G K IVE
Sbjct 175 LKDVPESMIVVGGGAIGVEMAWFYAKAGAKVTIVE 209
>P18925 Dihydrolipoyl dehydrogenase [Azotobacter vinelandii]
Length=477
Score = 342 bits (877), Expect = 1e-116
Identities = 188/471 (40%), Positives = 282/471 (60%), Gaps = 11/471 (2%)
Query 7 QFDLVVIGAGPGGYVAAIRAAQLGLKTAIVEA-------THLGGICLNWGCIPTKALLAG 59
+FD++VIGAGPGGYVAAI++AQLGLKTA++E T LGG CLN GCIP+KALL
Sbjct 4 KFDVIVIGAGPGGYVAAIKSAQLGLKTALIEKYKGKEGKTALGGTCLNVGCIPSKALLDS 63
Query 60 AELAHQFKHASQF-GFELGDINFDLSKLVQHSRQVSAQLVQGIEHLLRKNQVSVFYAKAR 118
+ H+ + + G G++ D+ ++ Q+ L G+ L++ N V++F +
Sbjct 64 SYKFHEAHESFKLHGISTGEVAIDVPTMIARKDQIVRNLTGGVASLIKANGVTLFEGHGK 123
Query 119 FIAKERLELVDAQQQKQMIRAPHIIVATGAHAASLPQIPVDGDYVWSYKEALQPKQLPKS 178
+A +++E+ A Q++ ++I+A+G+ +P PVD D + AL + +P
Sbjct 124 LLAGKKVEVTAADGSSQVLDTENVILASGSKPVEIPPAPVDQDVIVDSTGALDFQNVPGK 183
Query 179 LLVIGSGAIGSEFASLYQDLGSQVTLLDLARQILPTEDHEVAQYVRKQFEQKGMRILTES 238
L VIG+G IG E S++ LG++VT+L+ + LP D +VA+ +K ++G++IL +
Sbjct 184 LGVIGAGVIGLELGSVWARLGAEVTVLEAMDKFLPAVDEQVAKEAQKILTKQGLKILLGA 243
Query 239 TVQHLEVCEGKVHCEIHDPSGVQSLSFDHVLSAVGVKPNTQNLGLEQLGVALTN-GFIQT 297
V EV +V + D G +S +FD ++ AVG +P T +L GV L GFI
Sbjct 244 RVTGTEVKNKQVTVKFVDAEGEKSQAFDKLIVAVGRRPVTTDLLAADSGVTLDERGFIYV 303
Query 298 DEWCRTNVVGIYAIGDVAGAPCLAHKASHEAILCVEKIAGIADVHPLNRLQIPGCIFTHP 357
D++C T+V G+YAIGDV LAHKAS E ++ E+IAG +N IP I+THP
Sbjct 304 DDYCATSVPGVYAIGDVVRGAMLAHKASEEGVVVAERIAG--HKAQMNYDLIPAVIYTHP 361
Query 358 QVASIGLTEQQAKAEGKQIHIGKFPMSANGKAIALGQTAGFVKTIVDVESGELLGAHMVG 417
++A +G TEQ KAEG I++G FP +A+G+A+A TAGFVK I D ++ +LG H++G
Sbjct 362 EIAGVGKTEQALKAEGVAINVGVFPFAASGRAMAANDTAGFVKVIADAKTDRVLGVHVIG 421
Query 418 HEVTEQIQGYAIAQALEATDEHLAQVIFPHPTLSEAMHESILASMQRAIHI 468
E +Q AIA + E L ++F HP LSEA+HE+ LA AIH+
Sbjct 422 PSAAELVQQGAIAMEFGTSAEDLGMMVFAHPALSEALHEAALAVSGHAIHV 472
>P9WHH8 Dihydrolipoyl dehydrogenase [Mycobacterium tuberculosis
(strain CDC 1551 / Oshkosh)]
Length=464
Score = 335 bits (860), Expect = 3e-114
Identities = 189/454 (42%), Positives = 273/454 (60%), Gaps = 6/454 (1%)
Query 6 TQFDLVVIGAGPGGYVAAIRAAQLGLKTAIVEATHLGGICLNWGCIPTKALLAGAELAHQ 65
T +D+VV+GAGPGGYVAAIRAAQLGL TAIVE + GG+CLN GCIP+KALL AEL H
Sbjct 2 THYDVVVLGAGPGGYVAAIRAAQLGLSTAIVEPKYWGGVCLNVGCIPSKALLRNAELVHI 61
Query 66 F-KHASQFGFELGDINFDLSKLVQHSRQVSAQLVQGIEHLLRKNQVSVFYAKARFIAKER 124
F K A FG G++ FD SR+V+ V G+ L++KN+++ + F
Sbjct 62 FTKDAKAFGIS-GEVTFDYGIAYDRSRKVAEGRVAGVHFLMKKNKITEIHGYGTFADANT 120
Query 125 LELVDAQQQ-KQMIRAPHIIVATGAHAASLPQIPVDGDYVWSYKEALQPKQLPKSLLVIG 183
L LVD + + + I+ATG+ +P + + V +Y+E + ++LPKS+++ G
Sbjct 121 L-LVDLNDGGTESVTFDNAIIATGSSTRLVPGTSLSANVV-TYEEQILSRELPKSIIIAG 178
Query 184 SGAIGSEFASLYQDLGSQVTLLDLARQILPTEDHEVAQYVRKQFEQKGMRILTESTVQHL 243
+GAIG EF + ++ G VT+++ + LP ED +V++ + KQF++ G+ ILT + V+ +
Sbjct 179 AGAIGMEFGYVLKNYGVDVTIVEFLPRALPNEDADVSKEIEKQFKKLGVTILTATKVESI 238
Query 244 EVCEGKVHCEIHDPSGVQSLSFDHVLSAVGVKPNTQNLGLEQLGVALTNG-FIQTDEWCR 302
+V + Q L + VL A+G PN + GL++ GVALT+ I D++ R
Sbjct 239 ADGGSQVTVTVTKDGVAQELKAEKVLQAIGFAPNVEGYGLDKAGVALTDRKAIGVDDYMR 298
Query 303 TNVVGIYAIGDVAGAPCLAHKASHEAILCVEKIAGIADVHPLNRLQIPGCIFTHPQVASI 362
TNV IYAIGDV G LAH A + ++ E IAG + + +P F P VAS
Sbjct 299 TNVGHIYAIGDVNGLLQLAHVAEAQGVVAAETIAGAETLTLGDHRMLPRATFCQPNVASF 358
Query 363 GLTEQQAKAEGKQIHIGKFPMSANGKAIALGQTAGFVKTIVDVESGELLGAHMVGHEVTE 422
GLTEQQA+ EG + + KFP +AN KA +G +GFVK + D + GELLG H+VGH+V E
Sbjct 359 GLTEQQARNEGYDVVVAKFPFTANAKAHGVGDPSGFVKLVADAKHGELLGGHLVGHDVAE 418
Query 423 QIQGYAIAQALEATDEHLAQVIFPHPTLSEAMHE 456
+ +AQ + T LA+ + HPT+SEA+ E
Sbjct 419 LLPELTLAQRWDLTASELARNVHTHPTMSEALQE 452
>P66005 Dihydrolipoyl dehydrogenase [Mycobacterium bovis (strain
ATCC BAA-935 / AF2122/97)]
Length=464
Score = 335 bits (860), Expect = 3e-114
Identities = 189/454 (42%), Positives = 273/454 (60%), Gaps = 6/454 (1%)
Query 6 TQFDLVVIGAGPGGYVAAIRAAQLGLKTAIVEATHLGGICLNWGCIPTKALLAGAELAHQ 65
T +D+VV+GAGPGGYVAAIRAAQLGL TAIVE + GG+CLN GCIP+KALL AEL H
Sbjct 2 THYDVVVLGAGPGGYVAAIRAAQLGLSTAIVEPKYWGGVCLNVGCIPSKALLRNAELVHI 61
Query 66 F-KHASQFGFELGDINFDLSKLVQHSRQVSAQLVQGIEHLLRKNQVSVFYAKARFIAKER 124
F K A FG G++ FD SR+V+ V G+ L++KN+++ + F
Sbjct 62 FTKDAKAFGIS-GEVTFDYGIAYDRSRKVAEGRVAGVHFLMKKNKITEIHGYGTFADANT 120
Query 125 LELVDAQQQ-KQMIRAPHIIVATGAHAASLPQIPVDGDYVWSYKEALQPKQLPKSLLVIG 183
L LVD + + + I+ATG+ +P + + V +Y+E + ++LPKS+++ G
Sbjct 121 L-LVDLNDGGTESVTFDNAIIATGSSTRLVPGTSLSANVV-TYEEQILSRELPKSIIIAG 178
Query 184 SGAIGSEFASLYQDLGSQVTLLDLARQILPTEDHEVAQYVRKQFEQKGMRILTESTVQHL 243
+GAIG EF + ++ G VT+++ + LP ED +V++ + KQF++ G+ ILT + V+ +
Sbjct 179 AGAIGMEFGYVLKNYGVDVTIVEFLPRALPNEDADVSKEIEKQFKKLGVTILTATKVESI 238
Query 244 EVCEGKVHCEIHDPSGVQSLSFDHVLSAVGVKPNTQNLGLEQLGVALTNG-FIQTDEWCR 302
+V + Q L + VL A+G PN + GL++ GVALT+ I D++ R
Sbjct 239 ADGGSQVTVTVTKDGVAQELKAEKVLQAIGFAPNVEGYGLDKAGVALTDRKAIGVDDYMR 298
Query 303 TNVVGIYAIGDVAGAPCLAHKASHEAILCVEKIAGIADVHPLNRLQIPGCIFTHPQVASI 362
TNV IYAIGDV G LAH A + ++ E IAG + + +P F P VAS
Sbjct 299 TNVGHIYAIGDVNGLLQLAHVAEAQGVVAAETIAGAETLTLGDHRMLPRATFCQPNVASF 358
Query 363 GLTEQQAKAEGKQIHIGKFPMSANGKAIALGQTAGFVKTIVDVESGELLGAHMVGHEVTE 422
GLTEQQA+ EG + + KFP +AN KA +G +GFVK + D + GELLG H+VGH+V E
Sbjct 359 GLTEQQARNEGYDVVVAKFPFTANAKAHGVGDPSGFVKLVADAKHGELLGGHLVGHDVAE 418
Query 423 QIQGYAIAQALEATDEHLAQVIFPHPTLSEAMHE 456
+ +AQ + T LA+ + HPT+SEA+ E
Sbjct 419 LLPELTLAQRWDLTASELARNVHTHPTMSEALQE 452
>P9WHH9 Dihydrolipoyl dehydrogenase [Mycobacterium tuberculosis
(strain ATCC 25618 / H37Rv)]
Length=464
Score = 335 bits (860), Expect = 3e-114
Identities = 189/454 (42%), Positives = 273/454 (60%), Gaps = 6/454 (1%)
Query 6 TQFDLVVIGAGPGGYVAAIRAAQLGLKTAIVEATHLGGICLNWGCIPTKALLAGAELAHQ 65
T +D+VV+GAGPGGYVAAIRAAQLGL TAIVE + GG+CLN GCIP+KALL AEL H
Sbjct 2 THYDVVVLGAGPGGYVAAIRAAQLGLSTAIVEPKYWGGVCLNVGCIPSKALLRNAELVHI 61
Query 66 F-KHASQFGFELGDINFDLSKLVQHSRQVSAQLVQGIEHLLRKNQVSVFYAKARFIAKER 124
F K A FG G++ FD SR+V+ V G+ L++KN+++ + F
Sbjct 62 FTKDAKAFGIS-GEVTFDYGIAYDRSRKVAEGRVAGVHFLMKKNKITEIHGYGTFADANT 120
Query 125 LELVDAQQQ-KQMIRAPHIIVATGAHAASLPQIPVDGDYVWSYKEALQPKQLPKSLLVIG 183
L LVD + + + I+ATG+ +P + + V +Y+E + ++LPKS+++ G
Sbjct 121 L-LVDLNDGGTESVTFDNAIIATGSSTRLVPGTSLSANVV-TYEEQILSRELPKSIIIAG 178
Query 184 SGAIGSEFASLYQDLGSQVTLLDLARQILPTEDHEVAQYVRKQFEQKGMRILTESTVQHL 243
+GAIG EF + ++ G VT+++ + LP ED +V++ + KQF++ G+ ILT + V+ +
Sbjct 179 AGAIGMEFGYVLKNYGVDVTIVEFLPRALPNEDADVSKEIEKQFKKLGVTILTATKVESI 238
Query 244 EVCEGKVHCEIHDPSGVQSLSFDHVLSAVGVKPNTQNLGLEQLGVALTNG-FIQTDEWCR 302
+V + Q L + VL A+G PN + GL++ GVALT+ I D++ R
Sbjct 239 ADGGSQVTVTVTKDGVAQELKAEKVLQAIGFAPNVEGYGLDKAGVALTDRKAIGVDDYMR 298
Query 303 TNVVGIYAIGDVAGAPCLAHKASHEAILCVEKIAGIADVHPLNRLQIPGCIFTHPQVASI 362
TNV IYAIGDV G LAH A + ++ E IAG + + +P F P VAS
Sbjct 299 TNVGHIYAIGDVNGLLQLAHVAEAQGVVAAETIAGAETLTLGDHRMLPRATFCQPNVASF 358
Query 363 GLTEQQAKAEGKQIHIGKFPMSANGKAIALGQTAGFVKTIVDVESGELLGAHMVGHEVTE 422
GLTEQQA+ EG + + KFP +AN KA +G +GFVK + D + GELLG H+VGH+V E
Sbjct 359 GLTEQQARNEGYDVVVAKFPFTANAKAHGVGDPSGFVKLVADAKHGELLGGHLVGHDVAE 418
Query 423 QIQGYAIAQALEATDEHLAQVIFPHPTLSEAMHE 456
+ +AQ + T LA+ + HPT+SEA+ E
Sbjct 419 LLPELTLAQRWDLTASELARNVHTHPTMSEALQE 452
>Q50068 Dihydrolipoyl dehydrogenase [Mycobacterium leprae (strain
TN)]
Length=467
Score = 334 bits (856), Expect = 1e-113
Identities = 187/456 (41%), Positives = 274/456 (60%), Gaps = 7/456 (2%)
Query 6 TQFDLVVIGAGPGGYVAAIRAAQLGLKTAIVEATHLGGICLNWGCIPTKALLAGAELAHQ 65
T +D+VV+GAGPGGYVAAIRAAQLGL TA+VE + GGICLN GCIP+K LL AELAH
Sbjct 2 THYDVVVLGAGPGGYVAAIRAAQLGLSTAVVEPKYWGGICLNVGCIPSKVLLHNAELAHI 61
Query 66 F-KHASQFGFELGDINFDLSKLVQHSRQVSAQLVQGIEHLLRKNQVSVFYAKARFIAKER 124
F K A FG GD +FD SR+VS V G+ L++KN+++ + RF
Sbjct 62 FTKEAKTFGIS-GDASFDYGIAYDRSRKVSEGRVAGVHFLMKKNKITEIHGYGRFTDANT 120
Query 125 L--ELVDAQQQKQM-IRAPHIIVATGAHAASLPQIPVDGDYVWSYKEALQPKQLPKSLLV 181
L EL + + + + ++I+ATG+ +P + + + +Y+E + ++LP S+++
Sbjct 121 LSVELSEGVPETPLKVTFNNVIIATGSKTRLVPGTLLSTNVI-TYEEQILTRELPDSIVI 179
Query 182 IGSGAIGSEFASLYQDLGSQVTLLDLARQILPTEDHEVAQYVRKQFEQKGMRILTESTVQ 241
+G+GAIG EF + ++ G VT+++ + +P ED EV++ + KQF++ G++ILT + V+
Sbjct 180 VGAGAIGIEFGYVLKNYGVDVTIVEFLPRAMPNEDAEVSKEIEKQFKKMGIKILTGTKVE 239
Query 242 HLEVCEGKVHCEIHDPSGVQSLSFDHVLSAVGVKPNTQNLGLEQLGVALT-NGFIQTDEW 300
+ V + Q L D VL A+G PN GL+++GVALT + + D++
Sbjct 240 SISDNGSHVLVAVSKDGQFQELKADKVLQAIGFAPNVDGYGLDKVGVALTADKAVDIDDY 299
Query 301 CRTNVVGIYAIGDVAGAPCLAHKASHEAILCVEKIAGIADVHPLNRLQIPGCIFTHPQVA 360
+TNV IYAIGDV G LAH A + ++ E IAG + + +P F P VA
Sbjct 300 MQTNVSHIYAIGDVTGKLQLAHVAEAQGVVAAEAIAGAETLALSDYRMMPRATFCQPNVA 359
Query 361 SIGLTEQQAKAEGKQIHIGKFPMSANGKAIALGQTAGFVKTIVDVESGELLGAHMVGHEV 420
S GLTEQQA+ G + + KFP +AN KA +G +GFVK + D + GELLG HM+GH V
Sbjct 360 SFGLTEQQARDGGYDVVVAKFPFTANAKAHGMGDPSGFVKLVADAKYGELLGGHMIGHNV 419
Query 421 TEQIQGYAIAQALEATDEHLAQVIFPHPTLSEAMHE 456
+E + +AQ + T L + + HPTLSEA+ E
Sbjct 420 SELLPELTLAQKWDLTATELVRNVHTHPTLSEALQE 455
>P14218 Dihydrolipoyl dehydrogenase [Pseudomonas fluorescens]
Length=478
Score = 333 bits (854), Expect = 4e-113
Identities = 187/471 (40%), Positives = 275/471 (58%), Gaps = 11/471 (2%)
Query 7 QFDLVVIGAGPGGYVAAIRAAQLGLKTAIVEA-------THLGGICLNWGCIPTKALLAG 59
+FD+VVIGAGPGGYVAAIRAAQLGLKTA +E LGG CLN GCIP+KALL
Sbjct 4 KFDVVVIGAGPGGYVAAIRAAQLGLKTACIEKYIGKEGKVALGGTCLNVGCIPSKALLDS 63
Query 60 AELAHQFKHASQF-GFELGDINFDLSKLVQHSRQVSAQLVQGIEHLLRKNQVSVFYAKAR 118
+ H+ K A + G E + D+ +V + L GI L + N V+ F +
Sbjct 64 SYKYHEAKEAFKVHGIEAKGVTIDVPAMVARKANIVKNLTGGIATLFKANGVTSFEGHGK 123
Query 119 FIAKERLELVDAQQQKQMIRAPHIIVATGAHAASLPQIPVDGDYVWSYKEALQPKQLPKS 178
+A +++E+ + Q++ A ++I+A+G+ +P P+ D + AL+ + +PK
Sbjct 124 LLANKQVEVTGLDGKTQVLEAENVIIASGSRPVEIPPAPLSDDIIVDSTGALEFQAVPKK 183
Query 179 LLVIGSGAIGSEFASLYQDLGSQVTLLDLARQILPTEDHEVAQYVRKQFEQKGMRILTES 238
L VIG+G IG E S++ LG++VT+L+ + LP D ++A+ K ++G+ I +
Sbjct 184 LGVIGAGVIGLELGSVWARLGAEVTVLEALDKFLPAADEQIAKEALKVLTKQGLNIRLGA 243
Query 239 TVQHLEVCEGKVHCEIHDPSGVQSLSFDHVLSAVGVKPNTQNLGLEQLGVALTN-GFIQT 297
V EV + +V D +G Q +FD ++ AVG +P T +L GV L GFI
Sbjct 244 RVTASEVKKKQVTVTFTDANGEQKETFDKLIVAVGRRPVTTDLLAADSGVTLDERGFIYV 303
Query 298 DEWCRTNVVGIYAIGDVAGAPCLAHKASHEAILCVEKIAGIADVHPLNRLQIPGCIFTHP 357
D+ C+T+V G++AIGDV LAHKAS E ++ E+IAG +N IP I+THP
Sbjct 304 DDHCKTSVPGVFAIGDVVRGAMLAHKASEEGVMVAERIAG--HKAQMNYDLIPSVIYTHP 361
Query 358 QVASIGLTEQQAKAEGKQIHIGKFPMSANGKAIALGQTAGFVKTIVDVESGELLGAHMVG 417
++A +G TEQ KAEG ++++G FP +A+G+A+A T G VK I D ++ +LG H++G
Sbjct 362 EIAWVGKTEQTLKAEGVEVNVGTFPFAASGRAMAANDTTGLVKVIADAKTDRVLGVHVIG 421
Query 418 HEVTEQIQGYAIAQALEATDEHLAQVIFPHPTLSEAMHESILASMQRAIHI 468
E +Q AI + E L ++F HPTLSEA+HE+ LA AIHI
Sbjct 422 PSAAELVQQGAIGMEFGTSAEDLGMMVFSHPTLSEALHEAALAVNGHAIHI 472
>Q9I3D1 Dihydrolipoyl dehydrogenase [Pseudomonas aeruginosa (strain
ATCC 15692 / DSM 22644 / CIP 104116 / JCM 14847 / LMG
12228 / 1C / PRS 101 / PAO1)]
Length=478
Score = 333 bits (853), Expect = 5e-113
Identities = 187/471 (40%), Positives = 275/471 (58%), Gaps = 11/471 (2%)
Query 7 QFDLVVIGAGPGGYVAAIRAAQLGLKTAIVEA-------THLGGICLNWGCIPTKALLAG 59
+FD+VVIGAGPGGYVAAIRAAQLGLKTA +E LGG CLN GCIP+KALL
Sbjct 4 KFDVVVIGAGPGGYVAAIRAAQLGLKTACIEKYIGKEGKVALGGTCLNVGCIPSKALLDS 63
Query 60 AELAHQFKHASQF-GFELGDINFDLSKLVQHSRQVSAQLVQGIEHLLRKNQVSVFYAKAR 118
+ H+ K A + G E + D+ +V + L GI L + N V+ F +
Sbjct 64 SYKYHEAKEAFKVHGIEAKGVTIDVPAMVARKANIVKNLTGGIATLFKANGVTSFEGHGK 123
Query 119 FIAKERLELVDAQQQKQMIRAPHIIVATGAHAASLPQIPVDGDYVWSYKEALQPKQLPKS 178
+A +++E+ + Q++ A ++I+A+G+ +P P+ D + AL+ + +PK
Sbjct 124 LLANKQVEVTGLDGKTQVLEAENVIIASGSRPVEIPPAPLTDDIIVDSTGALEFQAVPKK 183
Query 179 LLVIGSGAIGSEFASLYQDLGSQVTLLDLARQILPTEDHEVAQYVRKQFEQKGMRILTES 238
L VIG+G IG E S++ LG++VT+L+ + LP D ++A+ K ++G+ I +
Sbjct 184 LGVIGAGVIGLELGSVWARLGAEVTVLEALDKFLPAADEQIAKEALKVLTKQGLNIRLGA 243
Query 239 TVQHLEVCEGKVHCEIHDPSGVQSLSFDHVLSAVGVKPNTQNLGLEQLGVALTN-GFIQT 297
V EV + +V D +G Q +FD ++ AVG +P T +L GV L GFI
Sbjct 244 RVTASEVKKKQVTVTFTDANGEQKETFDKLIVAVGRRPVTTDLLAADSGVTLDERGFIYV 303
Query 298 DEWCRTNVVGIYAIGDVAGAPCLAHKASHEAILCVEKIAGIADVHPLNRLQIPGCIFTHP 357
D+ C+T+V G++AIGDV LAHKAS E ++ E+IAG +N IP I+THP
Sbjct 304 DDHCKTSVPGVFAIGDVVRGAMLAHKASEEGVMVAERIAG--HKAQMNYDLIPSVIYTHP 361
Query 358 QVASIGLTEQQAKAEGKQIHIGKFPMSANGKAIALGQTAGFVKTIVDVESGELLGAHMVG 417
++A +G TEQ KAEG ++++G FP +A+G+A+A T G VK I D ++ +LG H++G
Sbjct 362 EIAWVGKTEQTLKAEGVEVNVGTFPFAASGRAMAANDTTGLVKVIADAKTDRVLGVHVIG 421
Query 418 HEVTEQIQGYAIAQALEATDEHLAQVIFPHPTLSEAMHESILASMQRAIHI 468
E +Q AI + E L ++F HPTLSEA+HE+ LA AIHI
Sbjct 422 PSAAELVQQGAIGMEFGTSAEDLGMMVFSHPTLSEALHEAALAVNGHAIHI 472
>O34324 Dihydrolipoyl dehydrogenase [Bacillus subtilis (strain
168)]
Length=458
Score = 325 bits (832), Expect = 4e-110
Identities = 179/462 (39%), Positives = 275/462 (60%), Gaps = 11/462 (2%)
Query 10 LVVIGAGPGGYVAAIRAAQLGLKTAIVEATHLGGICLNWGCIPTKALLAGAELAHQFKHA 69
L +IG GP GY AA+ AAQ G +++ LGG CLN GCIPTK+LL A + + KHA
Sbjct 3 LAIIGGGPAGYAAAVSAAQQGRNVLLIDKGKLGGTCLNEGCIPTKSLLESANVLDKIKHA 62
Query 70 SQFGFEL--GDINFDLSKLVQHSRQVSAQLVQGIEHLLRKNQVSVFYAKARFIAKERLEL 127
FG EL G I+ D SK+ +QV +QLVQG+++L++KNQ+ V A F+++ +L L
Sbjct 63 DSFGIELPAGAISVDWSKMQSRKQQVVSQLVQGVQYLMKKNQIQVVKGTASFLSERKL-L 121
Query 128 VDAQQQKQMIRAPHIIVATGAHAASLPQIPVDGDYVWSYKEALQPKQLPKSLLVIGSGAI 187
++ + K++ A +++A+G+ LP P DG+++ K+AL ++P SL+++G G I
Sbjct 122 IEGENGKEIREADQVLIASGSEPIELPFAPFDGEWILDSKDALSLSEIPSSLVIVGGGVI 181
Query 188 GSEFASLYQDLGSQVTLLDLARQILPTEDHEVAQYVRKQFEQKGMRILTESTVQHLEVCE 247
G E+A L+ LGSQVT+++ A +++P ED ++A+ +++ E+ G+ + T S + ++
Sbjct 182 GCEYAGLFARLGSQVTIIETADRLIPAEDEDIARLFQEKLEEDGVEVHTSSRLGRVDQTA 241
Query 248 GKVHCEIHDPSGVQSLSF--DHVLSAVGVKPNTQNLGLEQLGVALTNGFIQTDEWCRTNV 305
+ SG + D+VL A+G KP L LEQ GV + I + +TNV
Sbjct 242 KTAIWK----SGQREFKTKADYVLVAIGRKPRLDGLQLEQAGVDFSPKGIPVNGHMQTNV 297
Query 306 VGIYAIGDVAGAPCLAHKASHEAILCVEKIAGIADVHPLNRLQIPGCIFTHPQVASIGLT 365
IYA GD G LAH A HE I+ +G DV +N +P CI+T P++A IG+T
Sbjct 298 PHIYACGDAIGGIQLAHAAFHEGIIAASHASG-RDVK-INEKHVPRCIYTSPEIACIGMT 355
Query 366 EQQAKAEGKQIHIGKFPMSANGKAIALGQTAGFVKTIVDVESGELLGAHMVGHEVTEQIQ 425
E+QA++ + IG+F SANGKA+ Q G VK + + E GE++G M+G +VTE I
Sbjct 356 ERQARSIYGDVKIGEFSFSANGKALIKQQAEGKVKIMAEPEFGEIVGVSMIGPDVTELIG 415
Query 426 GYAIAQALEATDEHLAQVIFPHPTLSEAMHESILASMQRAIH 467
A E T + I HPTLSE +HE++L+++ A+H
Sbjct 416 QAAAIMNGEMTADMAEHFIAAHPTLSETLHEALLSTIGLAVH 457
Score = 24.6 bits (52), Expect = 0.098
Identities = 13/37 (35%), Positives = 21/37 (57%), Gaps = 0/37 (0%)
Query 1 MSMSDTQFDLVVIGAGPGGYVAAIRAAQLGLKTAIVE 37
+S+S+ LV++G G G A A+LG + I+E
Sbjct 164 LSLSEIPSSLVIVGGGVIGCEYAGLFARLGSQVTIIE 200
Score = 18.9 bits (37), Expect = 6.1
Identities = 10/29 (34%), Positives = 13/29 (45%), Gaps = 0/29 (0%)
Query 178 SLLVIGSGAIGSEFASLYQDLGSQVTLLD 206
+L +IG G G A G V L+D
Sbjct 2 TLAIIGGGPAGYAAAVSAAQQGRNVLLID 30
>P52992 Dihydrolipoyl dehydrogenase [Cupriavidus necator (strain
ATCC 17699 / DSM 428 / KCTC 22496 / NCIMB 10442 / H16 / Stanier
337)]
Length=474
Score = 325 bits (832), Expect = 6e-110
Identities = 184/474 (39%), Positives = 272/474 (57%), Gaps = 15/474 (3%)
Query 7 QFDLVVIGAGPGGYVAAIRAAQLGLKTAIVEAT---------HLGGICLNWGCIPTKALL 57
QFD++VIGAGPGGY+AAIRA QLGL A E LGG CLN GCIP+KALL
Sbjct 4 QFDVLVIGAGPGGYIAAIRAGQLGLNVACCEGNPYDDPKGEARLGGTCLNVGCIPSKALL 63
Query 58 AGAELAHQFKH-ASQFGFELGDINFDLSKLVQHSRQVSAQLVQGIEHLLRKNQVSVFYAK 116
A +E +H G +GD+ D++K+++ + ++ +GIE L RKN+V++
Sbjct 64 ASSEEFENVQHHLGDHGITVGDVKVDVAKMLKRKDDIVGKMTKGIEFLFRKNKVTLLKGY 123
Query 117 ARFIAKERLELVDAQQQKQMIRAPHIIVATGAHAASLPQIPVDGDYVWSYKEALQPKQLP 176
+F+ K E +++ A +I+ATG+ A LP I VD D V + AL+ +P
Sbjct 124 GKFVGKSA-EGFQVDVAGEVVTAKQVIIATGSKARHLPGIKVDNDLVSDNEGALKFPAVP 182
Query 177 KSLLVIGSGAIGSEFASLYQDLGSQVTLLDLARQILPTEDHEVAQYVRKQFEQKGMRILT 236
K L VIG+G IG E S+++ LGS VT+L+ L D VA+ +KQ ++G++
Sbjct 183 KKLGVIGAGVIGLELGSVWRRLGSDVTVLEALPAFLGAADEGVAKEAQKQLTKQGLKFSL 242
Query 237 ESTVQHLEVCEGKVHCEIHDPSG-VQSLSFDHVLSAVGVKPNTQNLGLEQLGVALTN-GF 294
V + + V + D G Q+L D ++ +VG PNT NLGL+ +G+A GF
Sbjct 243 GVNVNEVTTGKNGVTVKYTDKDGKAQTLEVDRLIVSVGRVPNTDNLGLDAVGLAADQRGF 302
Query 295 IQTDEWCRTNVVGIYAIGDVAGAPCLAHKASHEAILCVEKIAGIADVHPLNRLQIPGCIF 354
I+ D+ C T V G++AIGDV P LAHKA E + E+IAG N +P I+
Sbjct 303 IEVDDHCATKVPGLWAIGDVVRGPMLAHKAEDEGVAVAERIAGQKPHIDYNC--VPWVIY 360
Query 355 THPQVASIGLTEQQAKAEGKQIHIGKFPMSANGKAIALGQTAGFVKTIVDVESGELLGAH 414
T P++A +G TE Q KAEG++ G+FP ANG+A+ +G GFVK + D ++ E+LG H
Sbjct 361 TFPEIAWVGKTEAQLKAEGREYKAGQFPFMANGRALGMGHADGFVKMLADAKTDEILGVH 420
Query 415 MVGHEVTEQIQGYAIAQALEATDEHLAQVIFPHPTLSEAMHESILASMQRAIHI 468
+V ++ I +A +A E + +V PHP++SE M E+ LA +R +++
Sbjct 421 IVAANASDLIAEAVVAMEFKAASEDIGRVCHPHPSMSEVMREAALAVDKRQLNM 474
>P31052 Dihydrolipoyl dehydrogenase [Pseudomonas putida]
Length=478
Score = 320 bits (820), Expect = 5e-108
Identities = 183/474 (39%), Positives = 277/474 (58%), Gaps = 17/474 (4%)
Query 7 QFDLVVIGAGPGGYVAAIRAAQLGLKTAIVEA-------THLGGICLNWGCIPTKALLAG 59
+FD+VVIGAGPGGYVAAI+AAQLGLKTA +E LGG CLN GCIP+KALL
Sbjct 4 KFDVVVIGAGPGGYVAAIKAAQLGLKTACIEKYTDAEGKLALGGTCLNVGCIPSKALL-- 61
Query 60 AELAHQFKHASQ----FGFELGDINFDLSKLVQHSRQVSAQLVQGIEHLLRKNQVSVFYA 115
+ + ++K A + G G++ D++ +V + L G+ L + N V+
Sbjct 62 -DSSWKYKEAKESFNVHGISTGEVKMDVAAMVGRKAGIVKNLTGGVATLFKANGVTSIQG 120
Query 116 KARFIAKERLELVDAQQQKQMIRAPHIIVATGAHAASLPQIPVDGDYVWSYKEALQPKQL 175
+ +A +++E+ A ++I A ++I+A+G+ +P PVD + + AL+ + +
Sbjct 121 HGKLLAGKKVEVTKADGTTEVIEAENVILASGSRPIDIPPAPVDQNVIVDSTGALEFQAV 180
Query 176 PKSLLVIGSGAIGSEFASLYQDLGSQVTLLDLARQILPTEDHEVAQYVRKQFEQKGMRIL 235
PK L VIG+G IG E S++ LG++VT+L+ L D V++ +K ++G+ I
Sbjct 181 PKRLGVIGAGVIGLELGSVWARLGAEVTVLEALDTFLMAADTAVSKEAQKTLTKQGLDIK 240
Query 236 TESTVQHLEVCEGKVHCEIHDPSGVQSLSFDHVLSAVGVKPNTQNLGLEQLGVALTN-GF 294
+ V +V +V + G Q ++FD ++ AVG +P T +L GV + G+
Sbjct 241 LGARVTGSKVNGNEVEVTYTNAEGEQKITFDKLIVAVGRRPVTTDLLAADSGVTIDERGY 300
Query 295 IQTDEWCRTNVVGIYAIGDVAGAPCLAHKASHEAILCVEKIAGIADVHPLNRLQIPGCIF 354
I D++C T+V G+YAIGDV LAHKAS E I+ VE+I G +N IP I+
Sbjct 301 IFVDDYCATSVPGVYAIGDVVRGMMLAHKASEEGIMVVERIKG--HKAQMNYDLIPSVIY 358
Query 355 THPQVASIGLTEQQAKAEGKQIHIGKFPMSANGKAIALGQTAGFVKTIVDVESGELLGAH 414
THP++A +G TEQ KAEG ++++G FP +A+G+A+A T GFVK I D ++ +LG H
Sbjct 359 THPEIAWVGKTEQALKAEGVEVNVGTFPFAASGRAMAANDTGGFVKVIADAKTDRVLGVH 418
Query 415 MVGHEVTEQIQGYAIAQALEATDEHLAQVIFPHPTLSEAMHESILASMQRAIHI 468
++G E +Q AIA + E L ++F HPTLSEA+HE+ LA AIH+
Sbjct 419 VIGPSAAELVQQGAIAMEFGTSAEDLGMMVFSHPTLSEALHEAALAVNGGAIHV 472
>P31023 Dihydrolipoyl dehydrogenase, mitochondrial [Pisum sativum]
Length=501
Score = 320 bits (821), Expect = 6e-108
Identities = 174/465 (37%), Positives = 279/465 (60%), Gaps = 7/465 (2%)
Query 9 DLVVIGAGPGGYVAAIRAAQLGLKTAIVEATH-LGGICLNWGCIPTKALLAGAELAHQFK 67
D+V+IG GPGGYVAAI+AAQLG KT +E LGG CLN GCIP+KALL + + H+ K
Sbjct 39 DVVIIGGGPGGYVAAIKAAQLGFKTTCIEKRGALGGTCLNVGCIPSKALLHSSHMYHEAK 98
Query 68 HA-SQFGFELGDINFDLSKLVQHSRQVSAQLVQGIEHLLRKNQVSVFYAKARFIAKERLE 126
H+ + G ++ ++ DL+ ++ + + L +GIE L +KN+V+ +F++ +
Sbjct 99 HSFANHGVKVSNVEIDLAAMMGQKDKAVSNLTRGIEGLFKKNKVTYVKGYGKFVSPSEIS 158
Query 127 LVDAQQQKQMIRAPHIIVATGAHAASLPQIPVDGDYVWSYKEALQPKQLPKSLLVIGSGA 186
+ + + +++ HII+ATG+ SLP + +D + S AL ++PK L+VIG+G
Sbjct 159 VDTIEGENTVVKGKHIIIATGSDVKSLPGVTIDEKKIVSSTGALALSEIPKKLVVIGAGY 218
Query 187 IGSEFASLYQDLGSQVTLLDLARQILPTEDHEVAQYVRKQFEQKGMRILTESTVQHLEVC 246
IG E S++ +GS+VT+++ A +I+PT D E+ + ++ E++GM+ ++ V ++
Sbjct 219 IGLEMGSVWGRIGSEVTVVEFASEIVPTMDAEIRKQFQRSLEKQGMKFKLKTKVVGVDTS 278
Query 247 EGKVHCEIHDPSGVQS--LSFDHVLSAVGVKPNTQNLGLEQLGVALTN-GFIQTDEWCRT 303
V + +G + + D VL + G P T L L+++GV G I +E T
Sbjct 279 GDGVKLTVEPSAGGEQTIIEADVVLVSAGRTPFTSGLNLDKIGVETDKLGRILVNERFST 338
Query 304 NVVGIYAIGDVAGAPCLAHKASHEAILCVEKIAGIADVHPLNRLQIPGCIFTHPQVASIG 363
NV G+YAIGDV P LAHKA + + CVE +AG V ++ ++PG ++T+P+VAS+G
Sbjct 339 NVSGVYAIGDVIPGPMLAHKAEEDGVACVEYLAG--KVGHVDYDKVPGVVYTNPEVASVG 396
Query 364 LTEQQAKAEGKQIHIGKFPMSANGKAIALGQTAGFVKTIVDVESGELLGAHMVGHEVTEQ 423
TE+Q K G + +GKFP AN +A A+ G VK I + E+ ++LG H++ E
Sbjct 397 KTEEQVKETGVEYRVGKFPFMANSRAKAIDNAEGLVKIIAEKETDKILGVHIMAPNAGEL 456
Query 424 IQGYAIAQALEATDEHLAQVIFPHPTLSEAMHESILASMQRAIHI 468
I AIA +A+ E +A+V HPT+SEA+ E+ +A+ + IHI
Sbjct 457 IHEAAIALQYDASSEDIARVCHAHPTMSEAIKEAAMATYDKPIHI 501
Score = 21.6 bits (44), Expect = 0.90
Identities = 12/37 (32%), Positives = 20/37 (54%), Gaps = 0/37 (0%)
Query 1 MSMSDTQFDLVVIGAGPGGYVAAIRAAQLGLKTAIVE 37
+++S+ LVVIGAG G ++G + +VE
Sbjct 202 LALSEIPKKLVVIGAGYIGLEMGSVWGRIGSEVTVVE 238
Lambda K H a alpha
0.321 0.135 0.395 0.792 4.96
Gapped
Lambda K H a alpha sigma
0.267 0.0410 0.140 1.90 42.6 43.6
Effective search space used: 2806410
Database: 5bd86ce5af357871930e746f54c4a47f.SwissProt.fasta
Posted date: May 8, 2024 8:20 PM
Number of letters in database: 7,562
Number of sequences in database: 16
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Neighboring words threshold: 11
Window for multiple hits: 40
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