BLASTP 2.12.0+
Reference: Stephen F. Altschul, Thomas L. Madden, Alejandro A.
Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J.
Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of
protein database search programs", Nucleic Acids Res. 25:3389-3402.
Reference for composition-based statistics: Alejandro A. Schaffer,
L. Aravind, Thomas L. Madden, Sergei Shavirin, John L. Spouge, Yuri
I. Wolf, Eugene V. Koonin, and Stephen F. Altschul (2001),
"Improving the accuracy of PSI-BLAST protein database searches with
composition-based statistics and other refinements", Nucleic Acids
Res. 29:2994-3005.
Database: 7d62acd3c072339bb54b8b620a602d43.SwissProt.fasta
11 sequences; 12,771 total letters
Query= ACIAD1124
Length=183
Score E
Sequences producing significant alignments: (Bits) Value
P54697 Myosin-J heavy chain [Dictyostelium discoideum] 56.2 2e-12
Q9D5R3 Centrosomal protein of 83 kDa [Mus musculus] 53.5 1e-11
Q6RHW0 Keratin, type I cytoskeletal 9 [Mus musculus] 52.4 3e-11
Q8VDC1 FYVE and coiled-coil domain-containing protein 1 [Mus musc... 51.6 6e-11
Q60952 Centrosome-associated protein CEP250 [Mus musculus] 51.6 6e-11
P40414 Tropomyosin-2 [Saccharomyces cerevisiae (strain ATCC 20450... 49.3 9e-11
P56536 Kinesin heavy chain isoform 5C [Rattus norvegicus] 50.8 1e-10
P28738 Kinesin heavy chain isoform 5C [Mus musculus] 50.4 1e-10
P21613 Kinesin heavy chain [Doryteuthis pealeii] 49.7 2e-10
P05659 Myosin-2 heavy chain, non muscle [Acanthamoeba castellanii] 43.5 3e-08
Q66H89 Centrosomal protein of 83 kDa [Rattus norvegicus] 38.9 1e-06
>P54697 Myosin-J heavy chain [Dictyostelium discoideum]
Length=2245
Score = 56.2 bits (134), Expect = 2e-12
Identities = 39/148 (26%), Positives = 74/148 (50%), Gaps = 7/148 (5%)
Query 29 LTQAKDESAAQHHSQIVQKNGIITAKQEEIDTLTEQLTQLQSQFKQLNTDATALADRYSR 88
+T ++ ++ ++ +K IT +E D L +QLTQLQ Q +Q +T + R
Sbjct 1471 VTTQMQQNQSRIERELEEKKQHITRIDDERDELKKQLTQLQQQHEQSSTQLLLAQNELER 1530
Query 89 LEKSCTDLKNRFQEILAERNELRVTKEKLQAQQRQTHQEVQELQQDRDRLQKKNELAKSK 148
L K K R E ++++ + + L+ + +Q+ +Q++ +L K++L+ SK
Sbjct 1531 LRKKELKYKERGHETSKQQDQFNMEIQSLRITNNDQLKSLQDYEQEKKKL--KDKLSSSK 1588
Query 149 VEAIIQRLSILGTSQD-----QHAQEIQ 171
EA QR SI+ + QH+Q ++
Sbjct 1589 QEAQQQRESIIKMDAELSAIKQHSQWVE 1616
Score = 46.6 bits (109), Expect = 3e-09
Identities = 44/169 (26%), Positives = 70/169 (41%), Gaps = 24/169 (14%)
Query 22 LESDNETLT---QAKDESAAQHHSQIVQKNGIITAKQEEIDTLTEQLTQLQSQF---KQL 75
LE NETL + +S Q Q I + E+ LT+ + +++F K+
Sbjct 1398 LERTNETLKSDFERVQQSLKQQERDCQQYKDTINRLENEVKQLTQLKERFENEFFVAKEQ 1457
Query 76 NTD-----------ATALADRYSRLEKSCTDLKNRFQEILAERNELRVTKEKLQAQQRQT 124
N++ T + SR+E+ + K I ER+EL+ +LQ Q Q+
Sbjct 1458 NSNQTQESVYLKEVTTQMQQNQSRIERELEEKKQHITRIDDERDELKKQLTQLQQQHEQS 1517
Query 125 HQEVQELQQDRDRLQKKNELAKSKVEAIIQRLSILGTSQDQHAQEIQQL 173
++ Q + +RL+KK K +R QDQ EIQ L
Sbjct 1518 STQLLLAQNELERLRKKELKYK-------ERGHETSKQQDQFNMEIQSL 1559
Score = 43.9 bits (102), Expect = 2e-08
Identities = 43/206 (21%), Positives = 85/206 (41%), Gaps = 28/206 (14%)
Query 3 EQLQRLQAHVGVLKTRLLHLESDNETLTQAKDE--------SAAQHHSQIVQKNGIITAK 54
+QL+ LQ + K L S + Q ++ SA + HSQ V+ N K
Sbjct 1565 DQLKSLQDYEQEKKKLKDKLSSSKQEAQQQRESIIKMDAELSAIKQHSQWVE-NSFTDMK 1623
Query 55 QEEIDTLTEQLTQLQSQFKQLNTDATALADRYSRLEKSCTDLKNRFQEILAERNELRVTK 114
Q + + Q +Q +T + + ++ + + K L+ Q++ + EL K
Sbjct 1624 QRNQELIESSALYKQQLLQQTSTIDSTIKEKENEISKLQQQLETSNQQLHQLKEELNSMK 1683
Query 115 EKLQAQQRQTHQEVQELQQDRDRLQK-KNELAKSKVEAIIQRLSILGTSQDQHA------ 167
+ Q + + +++ +L Q+ +L+ NE++K +A+ + I T ++Q
Sbjct 1684 QSNQLESTEQSKQLNQLIQENQQLKSVTNEISKQLDDAVFENQKINNTIKEQEIKSKRMS 1743
Query 168 ------------QEIQQLADPTEEIQ 181
QEIQQL +++
Sbjct 1744 VELQQHIDEGKQQEIQQLQSTIAQLK 1769
Score = 39.7 bits (91), Expect = 6e-07
Identities = 34/168 (20%), Positives = 78/168 (46%), Gaps = 15/168 (9%)
Query 26 NETLTQAKDESAAQHHSQIVQKN--GIITAKQEEIDTLTEQLTQLQSQFKQLNTDATALA 83
+E L++ ++++ HS + K ++ + + I+ L Q + + Q +Q + L+
Sbjct 1051 SECLSKLEEQTQQLDHSSKLNKKLEKDLSDQHDSIEKLQSQFNETEQQLQQFKQQSEELS 1110
Query 84 DRYSRLEKSCTDLKNRFQEILAERNELRVTKEKLQAQQ-RQTHQEVQE----LQQDRDRL 138
+ S+ + K F + ER+ T +L+ QQ ++ + ++E L RD L
Sbjct 1111 SKLSKTTQQLDFNKQEFDRLSQERDTDN-TNNQLEIQQLKKANSTLEEDYFSLSGIRDNL 1169
Query 139 QKK-------NELAKSKVEAIIQRLSILGTSQDQHAQEIQQLADPTEE 179
+++ N+L K +++++ Q+ S + Q+++QL E
Sbjct 1170 ERQVLELRDENQLIKERLDSLGQQSSQFQSGAALEKQQLEQLVQEQSE 1217
Score = 39.7 bits (91), Expect = 6e-07
Identities = 36/183 (20%), Positives = 85/183 (46%), Gaps = 12/183 (7%)
Query 3 EQLQRLQAHVGVLKTRLLHLESDNETLTQAKDESAAQHHSQIVQKNGIITAKQEEI---- 58
+Q + L + + +L + + + L+Q +D + +I Q + +E+
Sbjct 1104 QQSEELSSKLSKTTQQLDFNKQEFDRLSQERDTDNTNNQLEIQQLKKANSTLEEDYFSLS 1163
Query 59 ---DTLTEQLTQLQSQFKQLNTDATALADRYSRLEKSCTDLKNRFQEILAERNE--LRVT 113
D L Q+ +L+ + + + +L + S+ + K + ++++ E++E ++++
Sbjct 1164 GIRDNLERQVLELRDENQLIKERLDSLGQQSSQFQSGAALEKQQLEQLVQEQSEQLIKLS 1223
Query 114 KEKLQAQQ---RQTHQEVQELQQDRDRLQKKNELAKSKVEAIIQRLSILGTSQDQHAQEI 170
EKL +++ +Q +Q EL + +LQ + +L + E I + L QD+ Q
Sbjct 1224 SEKLGSEEEAKKQINQLELELTDHKSKLQIQLQLTEQSNEKIKKLKGKLEEYQDEKKQLQ 1283
Query 171 QQL 173
Q+L
Sbjct 1284 QEL 1286
Score = 36.6 bits (83), Expect = 7e-06
Identities = 32/144 (22%), Positives = 62/144 (43%), Gaps = 14/144 (10%)
Query 51 ITAKQEEIDTLTEQLTQLQSQFKQLNTDATALADRYSRLE----KSCTDLKN-------- 98
+ A+ + T+ EQ +LQ + ++L T+ A R +LE KS T +
Sbjct 966 LRAEARSLRTVQEQKNKLQEKLEELQWRLTSEAKRKQQLEDQKVKSDTTISELSSNNDHL 1025
Query 99 --RFQEILAERNELRVTKEKLQAQQRQTHQEVQELQQDRDRLQKKNELAKSKVEAIIQRL 156
+ EI + EL + + Q Q + +++E Q D K N+ + + +
Sbjct 1026 ELQLSEIQLKYQELDKSNQSSQLQLSECLSKLEEQTQQLDHSSKLNKKLEKDLSDQHDSI 1085
Query 157 SILGTSQDQHAQEIQQLADPTEEI 180
L + ++ Q++QQ +EE+
Sbjct 1086 EKLQSQFNETEQQLQQFKQQSEEL 1109
Score = 35.4 bits (80), Expect = 2e-05
Identities = 34/165 (21%), Positives = 64/165 (39%), Gaps = 8/165 (5%)
Query 21 HLESDNETLTQAKDESAAQHHSQIVQKNGIITAKQEEIDTLTEQLTQLQSQFKQLNTDAT 80
HLE + E + S +Q + ++ +E+ T+QL K+L D +
Sbjct 1024 HLELQLSEIQLKYQELDKSNQSSQLQLSECLSKLEEQ----TQQLDHSSKLNKKLEKDLS 1079
Query 81 ALADRYSRLEKSCTDLKNRFQEILAERNELRVTKEKLQAQQRQTHQEVQELQQDRDRLQK 140
D +L+ + + + Q+ + EL K Q QE L Q+RD
Sbjct 1080 DQHDSIEKLQSQFNETEQQLQQFKQQSEELSSKLSKTTQQLDFNKQEFDRLSQERDTDNT 1139
Query 141 KNELAKSKVEAIIQRLS----ILGTSQDQHAQEIQQLADPTEEIQ 181
N+L +++ L L +D +++ +L D + I+
Sbjct 1140 NNQLEIQQLKKANSTLEEDYFSLSGIRDNLERQVLELRDENQLIK 1184
Score = 34.3 bits (77), Expect = 4e-05
Identities = 38/188 (20%), Positives = 77/188 (41%), Gaps = 27/188 (14%)
Query 2 LEQLQ-RLQAHVGVLKTRLLHLESDNETLTQAKD--ESAAQHHSQIVQKNGIITAKQEEI 58
+ QL+ L H L+ +L E NE + + K E Q+ Q+ I ++ +
Sbjct 1237 INQLELELTDHKSKLQIQLQLTEQSNEKIKKLKGKLEEYQDEKKQLQQELERIKQSKQSV 1296
Query 59 DTLTEQLTQLQSQFKQLNTDATALADRYSRLEKSCTDLKNRFQEILAERNELRVTKEKLQ 118
+ ++ L +Q + ++T ++ S ++ T LK+ +E L + KLQ
Sbjct 1297 E---DEKNSLITQLTTVKFESTQVSTNVSHQKEKITTLKSTIEE-------LNKSIGKLQ 1346
Query 119 AQQRQTHQEVQELQ--------------QDRDRLQKKNELAKSKVEAIIQRLSILGTSQD 164
A+Q+ E++++Q ++ LQ + + + K E I L +
Sbjct 1347 AEQKNKDDEIRKIQFELNDQKQQFTRQTKEFSDLQSQQSIDRQKSEITIHSLERTNETLK 1406
Query 165 QHAQEIQQ 172
+ +QQ
Sbjct 1407 SDFERVQQ 1414
Score = 32.7 bits (73), Expect = 1e-04
Identities = 29/149 (19%), Positives = 63/149 (42%), Gaps = 12/149 (8%)
Query 22 LESDNETLTQAKDESAAQHHS-------QIVQKNGIITAKQEEIDTLTEQLTQLQSQFKQ 74
LE+ N+ L Q K+E + S Q Q N +I Q+ E QL +
Sbjct 1665 LETSNQQLHQLKEELNSMKQSNQLESTEQSKQLNQLIQENQQLKSVTNEISKQLDDAVFE 1724
Query 75 LNTDATALADRYSRLEKSCTDLKNRF-----QEILAERNELRVTKEKLQAQQRQTHQEVQ 129
+ ++ + ++ +L+ QEI ++ + K++ Q++ + +E+Q
Sbjct 1725 NQKINNTIKEQEIKSKRMSVELQQHIDEGKQQEIQQLQSTIAQLKQQQQSETDRLEKEIQ 1784
Query 130 ELQQDRDRLQKKNELAKSKVEAIIQRLSI 158
+++++R+ K E K + R+ +
Sbjct 1785 QMKRERETQMKLVESTKLNYHMLEDRMEL 1813
>Q9D5R3 Centrosomal protein of 83 kDa [Mus musculus]
Length=692
Score = 53.5 bits (127), Expect = 1e-11
Identities = 42/158 (27%), Positives = 76/158 (48%), Gaps = 13/158 (8%)
Query 2 LEQLQRLQAHVGVLKTRLLHLESDNETLTQAKDESAAQHHS-------QIVQKNGIITAK 54
+EQL R + H L +L LE++ L K+ S AQ + Q+ + + +
Sbjct 201 MEQLVREKTH---LLQKLKSLEAEVAELRAEKENSGAQVENVQRIQVRQLAEMQATLRSL 257
Query 55 QEEIDTLTEQLTQLQSQFKQLNTDATALADRYSRLEKSCTDLKNRFQEILAERNELRVTK 114
+ E + Q +L+ + + N T L + R ++ + L + +E L N+L +T
Sbjct 258 EAEKQSAKLQAERLEKELQSSNEQNTCLISKLHRADREISTLASEVKE-LKHANKLEITD 316
Query 115 EKLQAQQRQT--HQEVQELQQDRDRLQKKNELAKSKVE 150
KL+A + ++ +E ++Q + D LQ NE+ KS VE
Sbjct 317 IKLEAARAKSELERERNKIQSELDGLQSDNEILKSTVE 354
Score = 38.5 bits (88), Expect = 1e-06
Identities = 40/166 (24%), Positives = 73/166 (44%), Gaps = 27/166 (16%)
Query 15 LKTRLLHLESDNETLTQAKDESAAQHHSQIVQKNGIITAKQEEIDTLTEQLTQLQSQFKQ 74
+++ L L+SDNE L +S +HH ++ ++ E + ++Q+ ++
Sbjct 335 IQSELDGLQSDNEIL-----KSTVEHHKALL------------VEKDRELIRKVQAAKEE 377
Query 75 LNTDATALADRYSRLEKSCTDL-KNRFQEILAERNELRVTKEKLQAQQRQTHQEVQELQQ 133
L D LE +DL K + + + ++E +EKL+A Q +ELQ
Sbjct 378 GYQKLMVLQDEKLELENRLSDLEKMKVERDVWRQSEKEQCEEKLRASQMAEEAARRELQS 437
Query 134 DRDRLQ---------KKNELAKSKVEAIIQRLSILGTSQDQHAQEI 170
R +LQ +K +L S+++ I L I TS Q ++
Sbjct 438 TRLKLQQQIVNTEKAEKEKLENSELKQQISHLQIQVTSLTQSENDL 483
Score = 37.4 bits (85), Expect = 3e-06
Identities = 40/193 (21%), Positives = 78/193 (40%), Gaps = 38/193 (20%)
Query 3 EQLQRLQAHVGVLKTRLLHLESD----NETLTQAKDESAAQHHSQIVQKNGIITAKQEEI 58
E+++R +A L+ L+S+ E T+ +E ++ S++ +
Sbjct 130 EEVERYRAEYNKLRYEYTFLKSEFEHQKEEFTRVSEEEKMKYKSEVAR------------ 177
Query 59 DTLTEQLTQLQSQFKQLNTDATALADRYSRLEKSCTDLKNRFQEILAERNELRVTKE--- 115
L + +L +Q L+ D T + R +L + T L + + + AE ELR KE
Sbjct 178 --LEKDKEELHNQL--LSVDPTRDSKRMEQLVREKTHLLQKLKSLEAEVAELRAEKENSG 233
Query 116 ---------------KLQAQQRQTHQEVQELQQDRDRLQKKNELAKSKVEAIIQRLSILG 160
++QA R E Q + +RL+K+ + + + +I +L
Sbjct 234 AQVENVQRIQVRQLAEMQATLRSLEAEKQSAKLQAERLEKELQSSNEQNTCLISKLHRAD 293
Query 161 TSQDQHAQEIQQL 173
A E+++L
Sbjct 294 REISTLASEVKEL 306
Score = 36.2 bits (82), Expect = 8e-06
Identities = 40/182 (22%), Positives = 82/182 (45%), Gaps = 20/182 (11%)
Query 3 EQLQRLQAHVGVLKTRLLHLESDNETLTQAKDESAAQHHSQIVQKNGIITAKQEEIDTLT 62
E+ ++ + LK ++ HL+ +LTQ++++ +H ++ ++ L
Sbjct 450 EKAEKEKLENSELKQQISHLQIQVTSLTQSENDLLNSNH-----------MLKDMVERLK 498
Query 63 EQLTQLQSQFK--QLNTDATALADRYSRLEKSCTDLKNRFQEILAERNE-LRVTKEKLQA 119
++ L+SQ + QL+ + T + LE+ K++ E + +R E KEKLQ
Sbjct 499 QECRNLRSQAEKAQLDVEKTLEEKQIQWLEE-----KHKLHERITDREEKYNQAKEKLQR 553
Query 120 QQRQTHQEVQELQQDRDRLQKKNELAKSKVEAIIQRLSILGTSQDQHAQEIQQLADPTEE 179
+ + RLQ+K E+ ++K E + +L Q+ +E +L ++
Sbjct 554 AATAQKKRKSLHENKLKRLQEKVEVLEAKKEELETENQVL-NRQNVPFEEYTRLQKRLKD 612
Query 180 IQ 181
IQ
Sbjct 613 IQ 614
Score = 28.1 bits (61), Expect = 0.004
Identities = 20/80 (25%), Positives = 41/80 (51%), Gaps = 6/80 (8%)
Query 27 ETLTQAKDE----SAAQHHSQIVQKNGIITAKQEEIDTLTEQLTQLQSQFKQLNTDATAL 82
E QAK++ + AQ + + +N + QE+++ L + +L+++ + LN
Sbjct 542 EKYNQAKEKLQRAATAQKKRKSLHENKL-KRLQEKVEVLEAKKEELETENQVLNRQNVPF 600
Query 83 ADRYSRLEKSCTDLKNRFQE 102
+ Y+RL+K D++ R E
Sbjct 601 -EEYTRLQKRLKDIQRRHNE 619
Score = 26.9 bits (58), Expect = 0.009
Identities = 29/140 (21%), Positives = 69/140 (49%), Gaps = 11/140 (8%)
Query 39 QHHSQIVQKNGIITAKQEEIDTLTEQLTQLQSQFKQLNTDATALADRYSRL-EKSCTDLK 97
+HH Q A + E L E+ + Q++ K++ + A +++ L E +L
Sbjct 34 EHHKHNYQ------ALKIEHKRLQEEYVKSQNELKRVLIEKQASQEKFQLLLEDLRGELV 87
Query 98 NRFQEILAERNELRV-TKEKLQAQQRQTHQEVQELQQDRDR-LQKKNELAKSKVEAIIQR 155
+ ++I E+ +L+V T +KL+ + Q QE++ ++R R L ++ E +++ +
Sbjct 88 EKARDI--EKMKLQVLTPQKLELVKAQLQQELEAPMRERFRTLDEEVERYRAEYNKLRYE 145
Query 156 LSILGTSQDQHAQEIQQLAD 175
+ L + + +E ++++
Sbjct 146 YTFLKSEFEHQKEEFTRVSE 165
Score = 26.6 bits (57), Expect = 0.012
Identities = 31/151 (21%), Positives = 63/151 (42%), Gaps = 26/151 (17%)
Query 56 EEIDTLTEQLTQLQSQFKQ----LNTDATALADRYSRLEKSCTDLKNRFQEILAERNELR 111
EE L E++T + ++ Q L ATA R S E L+ + + + A++ EL
Sbjct 528 EEKHKLHERITDREEKYNQAKEKLQRAATAQKKRKSLHENKLKRLQEKVEVLEAKKEELE 587
Query 112 VTKEKLQAQQRQTHQEVQELQQDRDRLQKKNELAKSKVEA-------------IIQRLSI 158
T+ ++ +Q +E LQ+ +Q+++ +S + +++
Sbjct 588 -TENQVLNRQNVPFEEYTRLQKRLKDIQRRHNEFRSLILVPNMPPTASISPANFQSAVTV 646
Query 159 LGTS--------QDQHAQEIQQLADPTEEIQ 181
G ++QH +E+ L EE++
Sbjct 647 PGAELSFPPHLQEEQHQRELSLLRKRLEELE 677
>Q6RHW0 Keratin, type I cytoskeletal 9 [Mus musculus]
Length=743
Score = 52.4 bits (124), Expect = 3e-11
Identities = 41/153 (27%), Positives = 74/153 (48%), Gaps = 6/153 (4%)
Query 17 TRLLH-LESDNETLTQAKDESAAQHH-SQIVQKNGIITAKQEEIDTLTEQLTQLQSQFKQ 74
TR+L+ + + E L + QH+ S++ Q +T +E+++ +Q++QLQ ++
Sbjct 298 TRVLNDMREEYEQLISKNRQDIEQHYESKMTQIEQQMTNSGQEMESNMKQVSQLQHTIQE 357
Query 75 LNTDATALADRYSRLEKSCTDLKNRF----QEILAERNELRVTKEKLQAQQRQTHQEVQE 130
LN + S LEK+ D KNR+ Q+I + +EL +++A+ QE
Sbjct 358 LNVELQTQLTTKSALEKALEDTKNRYCGQLQQIQEQISELEAQLAEIRAETECQSQEYSI 417
Query 131 LQQDRDRLQKKNELAKSKVEAIIQRLSILGTSQ 163
L + RL+K+ E + +E Q G Q
Sbjct 418 LLSIKTRLEKEIETYRELLEGGQQDFESSGAGQ 450
Score = 23.1 bits (48), Expect = 0.16
Identities = 25/164 (15%), Positives = 70/164 (43%), Gaps = 17/164 (10%)
Query 27 ETLTQAKDESAAQHHSQIVQKNGIITAKQEEIDTLTEQLTQLQSQFKQLNTDATALADRY 86
+ L AK + S +KN + +EE+ LT Q +N +
Sbjct 243 DDLVMAKSDLEILLDSLEDEKNALTKNHKEEMSQLTGQ------NDGDVNVEINVAPS-- 294
Query 87 SRLEKSCTDLKNRFQEILAERN---ELRVTKEKLQAQQRQTH------QEVQELQQDRDR 137
+ L + D++ +++++++ E + Q +Q+ T+ ++++ Q +
Sbjct 295 TDLTRVLNDMREEYEQLISKNRQDIEQHYESKMTQIEQQMTNSGQEMESNMKQVSQLQHT 354
Query 138 LQKKNELAKSKVEAIIQRLSILGTSQDQHAQEIQQLADPTEEIQ 181
+Q+ N ++++ L +++++ ++QQ+ + E++
Sbjct 355 IQELNVELQTQLTTKSALEKALEDTKNRYCGQLQQIQEQISELE 398
Score = 21.2 bits (43), Expect = 0.65
Identities = 27/145 (19%), Positives = 59/145 (41%), Gaps = 22/145 (15%)
Query 58 IDTLTEQLTQLQSQFKQLNTDATALADRYSRLEKSCTDLKNRFQEILAERNELRVT-KEK 116
+D +L QS + + D L L + +DL+ + E+N L KE+
Sbjct 214 MDDFRVKLEMEQSLRQGVEGDINGLKKVLDDLVMAKSDLEILLDSLEDEKNALTKNHKEE 273
Query 117 LQAQQRQTHQEV----------------QELQQDRDRLQKKN-----ELAKSKVEAIIQR 155
+ Q +V +++++ ++L KN + +SK+ I Q+
Sbjct 274 MSQLTGQNDGDVNVEINVAPSTDLTRVLNDMREEYEQLISKNRQDIEQHYESKMTQIEQQ 333
Query 156 LSILGTSQDQHAQEIQQLADPTEEI 180
++ G + + +++ QL +E+
Sbjct 334 MTNSGQEMESNMKQVSQLQHTIQEL 358
>Q8VDC1 FYVE and coiled-coil domain-containing protein 1 [Mus
musculus]
Length=1437
Score = 51.6 bits (122), Expect = 6e-11
Identities = 52/199 (26%), Positives = 91/199 (46%), Gaps = 31/199 (16%)
Query 7 RLQAHVGVL-------KTRLLHLESDNETLTQAKDESAAQ--HHSQIVQKNGIITAK--Q 55
+LQ+ +GV KT + L+ NE L +A + Q I+Q+ I A+ +
Sbjct 767 KLQSQLGVAETVLREHKTLVQQLKEQNEALNRAHVQELLQCSEREGILQEESIYKAQKQE 826
Query 56 EEIDTLTEQLTQ--------------LQSQFKQLNTDATALADRYSRLEKSCTDLKNRFQ 101
+E+ L +L+Q LQ Q + NTD L + L T K+R +
Sbjct 827 QELRALQAELSQVRCSSEGAHLEHAELQDQLHRANTDTAELGIQVCAL----TAEKDRME 882
Query 102 EILAE-RNELRVTKEKLQAQQRQTHQEVQELQQDRDRLQKKNELAKSKVEAIIQRLSILG 160
E LA EL+ +KE +++ +V +LQQ++++LQ+K + A+ + L
Sbjct 883 EALASLAQELQDSKEAALQERKGLELQVMQLQQEKEKLQEKVKAAEEAASS-FSGLQAQL 941
Query 161 TSQDQHAQEIQQLADPTEE 179
+Q AQ +Q+ A ++
Sbjct 942 AQAEQLAQSLQETAHQEQD 960
Score = 43.9 bits (102), Expect = 2e-08
Identities = 46/208 (22%), Positives = 83/208 (40%), Gaps = 37/208 (18%)
Query 4 QLQRLQAHVGVLKTRLLHLESDNETLTQAKD---------ESAAQHHS------------ 42
QLQ L+ +G + + LE + L Q +D E A+ H
Sbjct 505 QLQLLETQLGQVSQLVSDLEEQKKQLMQERDHLSQRVGTLEQLAEVHGPPQSAEMPEKRQ 564
Query 43 -----QIVQKNGIITAKQEEIDTLTEQLTQ----LQSQFKQLNTDATALADRYSRLEKSC 93
+ V + + A+QEE+ + + L+ + + L TD AL R + ++ S
Sbjct 565 QCLREEQVNNSTVSEAEQEELQKELQNMVDRNQLLEGKLQALQTDYKALQQREAAIQGSL 624
Query 94 TDLKNRFQEILAERNELRVT-------KEKLQAQQRQTHQEVQELQQDRDRLQKKNELAK 146
L+ I N++ + KE ++AQ + +Q + + RLQ++ + +
Sbjct 625 ASLEAEQASIRHLGNQMEASLLAVKKAKETMKAQVAEKEAALQSKESECQRLQEEADQCR 684
Query 147 SKVEAIIQRLSILGTSQDQHAQEIQQLA 174
+ EA Q L L Q Q I+ L+
Sbjct 685 LQAEAQAQELRALENQCQQQIQLIEVLS 712
Score = 43.1 bits (100), Expect = 4e-08
Identities = 42/181 (23%), Positives = 80/181 (44%), Gaps = 15/181 (8%)
Query 6 QRLQAHVGVLKTRLLHLESDNETLTQAKDESAAQHHSQIVQKNGIITAKQEEI---DTLT 62
+ ++A V + L ES+ + L + D+ Q +Q + + Q++I + L+
Sbjct 653 ETMKAQVAEKEAALQSKESECQRLQEEADQCRLQAEAQAQELRALENQCQQQIQLIEVLS 712
Query 63 EQLTQLQSQFKQLNTDATALADRY--------SRLEKSCTDLKNRFQEILAERNELRVTK 114
+ Q Q+NTD AL+ RL+ DL+ + Q L +R++L+
Sbjct 713 AEKGQQGLSLPQVNTDQLALSQAQLEIHQGEAQRLQNEVVDLQAKLQVALGDRDKLQSQL 772
Query 115 EKLQAQQRQTHQEVQELQQDRDRLQK---KNELAKSKVEAIIQRLSIL-GTSQDQHAQEI 170
+ R+ VQ+L++ + L + + L S+ E I+Q SI Q+Q + +
Sbjct 773 GVAETVLREHKTLVQQLKEQNEALNRAHVQELLQCSEREGILQEESIYKAQKQEQELRAL 832
Query 171 Q 171
Q
Sbjct 833 Q 833
Score = 36.6 bits (83), Expect = 7e-06
Identities = 36/184 (20%), Positives = 81/184 (44%), Gaps = 6/184 (3%)
Query 2 LEQLQRLQAHVGVLKTRLLHLESD----NETLTQAKDESAAQHHSQIVQKNGIITAKQEE 57
LEQL + + L HL D E L+ K ESA Q Q+ + +++ +EE
Sbjct 419 LEQLAKELQLKEEARASLAHLVKDVVPLQEELSGKKQESA-QLRRQLQESLAHLSSVEEE 477
Query 58 IDTLTEQLTQLQSQFKQLNTDATALADRYSRLEKSCTDLKNRFQEILAERNELRVTKEKL 117
+ +Q Q + + + L +AT+L + LE + ++ ++ +L ++ L
Sbjct 478 LAEARQQEKQHREEKQLLEQEATSLTWQLQLLETQLGQVSQLVSDLEEQKKQLMQERDHL 537
Query 118 QAQQRQTHQEVQELQQDRDRLQKKNELAKSKVEAIIQRLSILGTSQDQHAQEIQQLADPT 177
+Q+ T +++ E+ + + + E + ++ Q++ +E+Q + D
Sbjct 538 -SQRVGTLEQLAEVHGPPQSAEMPEKRQQCLREEQVNNSTVSEAEQEELQKELQNMVDRN 596
Query 178 EEIQ 181
+ ++
Sbjct 597 QLLE 600
Score = 33.5 bits (75), Expect = 7e-05
Identities = 45/182 (25%), Positives = 81/182 (45%), Gaps = 23/182 (13%)
Query 15 LKTRLLHLESDNETLTQ---AKDESAAQH---HSQIVQKNGIITAKQE----EIDTLTEQ 64
L+ +++ L+ + E L + A +E+A+ +Q+ Q + + QE E D L Q
Sbjct 906 LELQVMQLQQEKEKLQEKVKAAEEAASSFSGLQAQLAQAEQLAQSLQETAHQEQDALKFQ 965
Query 65 LT----QLQSQFKQLNTDATALADRYSRLEKSCTDLKNRFQEI----LAERNELRVTKEK 116
L+ Q++ K N + L + + K QE+ A +L T
Sbjct 966 LSAEIMDHQNRLKTANEECGHLRAQLEEQGQQLQMTKEAVQELEITKAAMEEKLNCTSSH 1025
Query 117 L---QAQQRQTHQEVQELQQDRDRLQKKNELAKSKVEAIIQRLSILGTSQDQHAQEIQQL 173
L QA + +E LQ +R QK+ E A SK++ +L T+++++ Q++ L
Sbjct 1026 LAECQATLLRKDEESTMLQTSLERTQKELEKATSKIQEYYNKLCQEVTNRERNDQKM--L 1083
Query 174 AD 175
AD
Sbjct 1084 AD 1085
Score = 30.0 bits (66), Expect = 0.001
Identities = 32/152 (21%), Positives = 64/152 (42%), Gaps = 15/152 (10%)
Query 43 QIVQKNGIITAKQEEIDTLTEQLTQLQSQFKQLNTDATALADRYSR--------LEKSCT 94
Q+ Q+ + K + + + LQ+Q Q A +L + + L
Sbjct 912 QLQQEKEKLQEKVKAAEEAASSFSGLQAQLAQAEQLAQSLQETAHQEQDALKFQLSAEIM 971
Query 95 DLKNRFQEILAERNELRVTKEKLQAQQRQTHQEVQELQQDRDRLQKKNELAKS---KVEA 151
D +NR + E LR E+ Q + T + VQEL+ + +++K S + +A
Sbjct 972 DHQNRLKTANEECGHLRAQLEEQGQQLQMTKEAVQELEITKAAMEEKLNCTSSHLAECQA 1031
Query 152 IIQR----LSILGTSQDQHAQEIQQLADPTEE 179
+ R ++L TS ++ +E+++ +E
Sbjct 1032 TLLRKDEESTMLQTSLERTQKELEKATSKIQE 1063
Score = 28.9 bits (63), Expect = 0.002
Identities = 23/90 (26%), Positives = 45/90 (50%), Gaps = 15/90 (17%)
Query 87 SRLEKSCTDLKNRFQEILAERNELRVTKEKLQAQQRQTHQEVQELQQDRD---------- 136
S L+ +C+ L N E L +E+R+ ++L+ +++Q + VQ+L ++
Sbjct 216 SSLDLNCS-LNN---EALESFDEMRLELDQLEVREKQLQERVQQLDRENQALRMLVSRQG 271
Query 137 -RLQKKNELAKSKVEAIIQRLSILGTSQDQ 165
+LQ + E+ VE I +S++ Q Q
Sbjct 272 GQLQVEKEMGYLAVEDSIGLVSLVAELQKQ 301
Score = 27.3 bits (59), Expect = 0.007
Identities = 41/215 (19%), Positives = 78/215 (36%), Gaps = 40/215 (19%)
Query 4 QLQRLQAHVGVLKTRLLHLESDNETLTQAKDESAAQHHSQIVQKNGIITA---------- 53
+L +L+ L+ R+ L+ +N+ L Q Q+ ++ G +
Sbjct 238 ELDQLEVREKQLQERVQQLDRENQALRMLVSRQGGQ--LQVEKEMGYLAVEDSIGLVSLV 295
Query 54 ----KQEEIDTLTEQLTQLQSQFKQLNTDATALADRYSRLEKSCTDLKN------RFQEI 103
KQ ++ T + Q Q +LN D + +LE +L R ++
Sbjct 296 AELQKQGDVSQATVKKLQSCLQALELNVDKKEYSPSALQLENMAKELDTVRGSLGRENQL 355
Query 104 LAERNELRVTKEKLQAQQRQT--HQE----------------VQELQQDRDRLQKKNELA 145
LA +E EK + T HQE +Q L+ + Q+ N
Sbjct 356 LASLSERLARAEKGEKTPPDTELHQEPVPADLVLKFQELKGKLQALEGENTEAQELNRQQ 415
Query 146 KSKVEAIIQRLSILGTSQDQHAQEIQQLADPTEEI 180
K+E + + L + ++ A ++ + EE+
Sbjct 416 SIKLEQLAKELQLKEEARASLAHLVKDVVPLQEEL 450
Score = 25.8 bits (55), Expect = 0.022
Identities = 30/134 (22%), Positives = 58/134 (43%), Gaps = 18/134 (13%)
Query 3 EQLQRLQAHVGVLKTRL----LHLESDNETLTQAKDESAAQHHSQIVQKNGIITAKQEEI 58
E +Q L+ ++ +L HL TL + +ES S + Q+E+
Sbjct 1003 EAVQELEITKAAMEEKLNCTSSHLAECQATLLRKDEESTMLQTS--------LERTQKEL 1054
Query 59 DTLTEQLTQLQSQFKQLNT-----DATALADRYSRLEKSCTDLKNRFQEILAERNELRVT 113
+ T ++ + ++ Q T D LAD L ++ L+ R E+L +++ L
Sbjct 1055 EKATSKIQEYYNKLCQEVTNRERNDQKMLAD-LDDLNRTKKYLEERLIELLRDKDALWQK 1113
Query 114 KEKLQAQQRQTHQE 127
+ L+ QQ+ + +E
Sbjct 1114 SDALEFQQKLSAEE 1127
Score = 20.4 bits (41), Expect = 1.2
Identities = 28/136 (21%), Positives = 57/136 (42%), Gaps = 34/136 (25%)
Query 56 EEIDTLTEQLTQLQSQFKQLNTDATALADRYSRLEKSCTDLKNRFQEILAERNELRVTKE 115
E D + +L QL+ + KQ L+ R Q++ E LR+
Sbjct 230 ESFDEMRLELDQLEVREKQ---------------------LQERVQQLDRENQALRMLVS 268
Query 116 KLQAQQRQTHQEVQELQQDRD--------RLQKKNELAKS---KVEAIIQRLSILGTSQD 164
+ Q Q Q +E+ L + LQK+ +++++ K+++ +Q L L +
Sbjct 269 R-QGGQLQVEKEMGYLAVEDSIGLVSLVAELQKQGDVSQATVKKLQSCLQALE-LNVDKK 326
Query 165 QHAQEIQQLADPTEEI 180
+++ QL + +E+
Sbjct 327 EYSPSALQLENMAKEL 342
Score = 18.9 bits (37), Expect = 3.6
Identities = 13/43 (30%), Positives = 21/43 (49%), Gaps = 4/43 (9%)
Query 52 TAKQEEIDTLTEQLTQLQSQFKQ----LNTDATALADRYSRLE 90
T Q I L + T+L +FK+ + D+T+L +LE
Sbjct 8 TQLQRIIRDLQDAATELSHEFKEGGEPITDDSTSLHKFSYKLE 50
>Q60952 Centrosome-associated protein CEP250 [Mus musculus]
Length=2414
Score = 51.6 bits (122), Expect = 6e-11
Identities = 44/176 (25%), Positives = 80/176 (45%), Gaps = 14/176 (8%)
Query 3 EQLQRLQAHVGVLKTRLLHLESDNETLTQAKDESAAQH-------HSQIVQKNGIITAKQ 55
+QLQ L VG L H E + TL Q E+ Q Q+ + + +
Sbjct 1749 QQLQGLHRKVGETSLLLTHREQETATLQQHLQEAKEQGELREQVLQGQLEEAQRDLAQRD 1808
Query 56 EEIDTLTEQLTQLQSQFKQLNTDATALADRYSRLEKSCTDLKNRFQEILAERNELRVTKE 115
E++TL ++ Q Q Q + + +AL + LE++ LK R E+ R ++R +E
Sbjct 1809 HELETLRQEKQQTQDQEESMKLKTSAL---QAALEQAHATLKERQGELEEHREQVRRLQE 1865
Query 116 KLQAQQRQTHQEVQELQQDRDRLQKKNELAKSKVEAIIQRLSILGTSQDQHAQEIQ 171
+L+ + RQ V+ L++ L+ ++ + V A+ QR + + A+ +Q
Sbjct 1866 ELEVEGRQ----VRALEEVLGDLRAESREHEKAVLALQQRCAEQAQEHEAEARTLQ 1917
Score = 44.7 bits (104), Expect = 1e-08
Identities = 42/204 (21%), Positives = 86/204 (42%), Gaps = 27/204 (13%)
Query 5 LQRLQAHVGVLKTRLLHLESDNETLTQAKDESAAQH---HSQIVQKNGIITAKQEEIDTL 61
LQ+L V + L + L Q ++ AQ HS++ ++ QEE
Sbjct 1237 LQKLHQDVWKARQARDDLRDQVQKLVQRLTDTEAQKSQVHSELQDLQRQLSQSQEEKSKW 1296
Query 62 TEQLTQLQSQFKQLNTDATALADRYSRLEKSCTDLKNRFQEILAERNELRVTKEKLQAQQ 121
+ L+S+ + L+ A +L R + E + +N + + A + +L E LQA
Sbjct 1297 EGRQNSLESELRDLHETAASLQSRLRQAELQKMEAQNDRELLQASKEKLSAQVEHLQACV 1356
Query 122 RQTHQEV---------------------QELQQDRDR---LQKKNELAKSKVEAIIQRLS 157
+ + +EL+ +R+R LQ++ EL ++ +A+ + L+
Sbjct 1357 AEAQAQADAAAVLEEDLRTARSALKLKNEELESERERAQALQEQGELKVAQGKALQENLA 1416
Query 158 ILGTSQDQHAQEIQQLADPTEEIQ 181
+L + +E++ L +E++
Sbjct 1417 LLAQTLSNREREVETLQAEVQELE 1440
Score = 43.9 bits (102), Expect = 2e-08
Identities = 49/182 (27%), Positives = 88/182 (48%), Gaps = 27/182 (15%)
Query 2 LEQLQRLQAHVGVLKTRLLHLESDNETLTQAKDESAAQHHSQIVQKNGIITAKQEEIDTL 61
LE L+R +A L+T+L +++ E + ++E +Q S + Q + ++E + +L
Sbjct 878 LETLERERAE---LETKLREQQTEMEAIRAQREEERSQADSALYQMQ--LETEKERV-SL 931
Query 62 TEQLTQLQSQFKQLNTDATALADRYSRLEKSCTDLKNRFQEILAERNELRVTKEKLQAQQ 121
E L + Q + LAD +LE+ D+K ++ + + T LQAQ
Sbjct 932 LETLLRTQKE----------LADASQQLERLRQDMK-------IQKLKEQETTGMLQAQL 974
Query 122 RQTHQEVQE-LQQDRDRL---QKKNELAKSKVEAIIQRLSILGTSQDQHAQEIQQLADPT 177
++T QE++E QQ RD L QK + +VE ++ +L SQ +EI++
Sbjct 975 QETQQELKEAAQQHRDDLAAFQKDKLDLQKQVEDLMSQLVAHDDSQRLVKEEIEEKVKVA 1034
Query 178 EE 179
+E
Sbjct 1035 QE 1036
Score = 43.9 bits (102), Expect = 2e-08
Identities = 50/182 (27%), Positives = 79/182 (43%), Gaps = 18/182 (10%)
Query 3 EQLQRLQAHVGVLKTRLLHLESDNETLTQAKDESAA-QHHSQIVQKNGIITAKQEEIDTL 61
EQ Q +A L+ L ++ TLT+ + E AA + +Q ++ Q E L
Sbjct 1904 EQAQEHEAEARTLQDSWLQAQA---TLTEQEQELAALRAENQYSRRQEEAAVSQAE--AL 1958
Query 62 TEQLTQLQSQFKQLNTDATALADRYSRLEKSCTDLKNRFQEILAERNEL----RVTKEKL 117
E L++ Q+ ++ A+ LE S L+ A +L R+ + ++
Sbjct 1959 QEALSKAQAALQEKEQSLLEQAELSHTLEASTAALQATLDTCQASARQLEEALRIREGEI 2018
Query 118 QAQQRQTHQEVQELQQDRDRLQKKNELAKSKVEAIIQRLSILGTSQDQHAQEIQQLADPT 177
QAQ Q H+ Q LQQ + QKK EL + +A +R SQ+ QE Q L
Sbjct 2019 QAQALQHHEVTQHLQQ--ELCQKKEELRQLLEKAGARR------SQENGIQEKQSLEQER 2070
Query 178 EE 179
+E
Sbjct 2071 QE 2072
Score = 42.4 bits (98), Expect = 8e-08
Identities = 41/167 (25%), Positives = 73/167 (44%), Gaps = 10/167 (6%)
Query 3 EQLQRLQAHVGVLKTRLLHLESDNETLTQAKDESAAQHHSQIVQKNGI------ITAKQE 56
+QL+ L+ L+ + L+ ++ K E + H + ++ + + AKQ
Sbjct 478 QQLEVLEQEAWRLRRMNMELQLQGDSAQGEKLEQQEELHLAVRERERLQETLVGLEAKQS 537
Query 57 E----IDTLTEQLTQLQSQFKQLNTDATALADRYSRLEKSCTDLKNRFQEILAERNELRV 112
E + TL E L + + + L + +A +R E+S +L + AE +LR
Sbjct 538 ESLSELLTLREALESSRLEGELLKQERVEVAAALARAEQSIVELSGSENSLKAEVADLRA 597
Query 113 TKEKLQAQQRQTHQEVQELQQDRDRLQKKNELAKSKVEAIIQRLSIL 159
KL A + EL Q +L+++N+ S+VEA Q S L
Sbjct 598 AAVKLGALNEALALDKVELNQQLLQLEQENQSLCSRVEAAEQLRSAL 644
Score = 42.4 bits (98), Expect = 8e-08
Identities = 38/170 (22%), Positives = 75/170 (44%), Gaps = 7/170 (4%)
Query 18 RLLHLESDNETLTQAKDESAAQHHSQIVQ-KNGIITAKQEEIDTLTEQLTQLQSQFKQLN 76
+L+H +D+ + +H I++ K + +QE I L + QL+ Q + L+
Sbjct 1696 QLVHERADDGKSPSKGQRGSLEHLKLILRDKEKEVECQQERIQELQGHMGQLEQQLQGLH 1755
Query 77 TDATALADRYSRLEKSCTDLKNRFQEILAERNELR--VTKEKLQAQQR---QTHQEVQEL 131
+ + E+ L+ QE E+ ELR V + +L+ QR Q E++ L
Sbjct 1756 RKVGETSLLLTHREQETATLQQHLQE-AKEQGELREQVLQGQLEEAQRDLAQRDHELETL 1814
Query 132 QQDRDRLQKKNELAKSKVEAIIQRLSILGTSQDQHAQEIQQLADPTEEIQ 181
+Q++ + Q + E K K A+ L + + E+++ + +Q
Sbjct 1815 RQEKQQTQDQEESMKLKTSALQAALEQAHATLKERQGELEEHREQVRRLQ 1864
Score = 41.6 bits (96), Expect = 1e-07
Identities = 37/171 (22%), Positives = 80/171 (47%), Gaps = 19/171 (11%)
Query 4 QLQRLQAHVGVLKTRLLHLESDNETLTQAKDESAAQHHSQIVQKNGIITAKQEEIDTLTE 63
Q+Q L+ +G L+ L LE + + +++ + + Q + +T +++ ++
Sbjct 1536 QIQDLKKQLGTLECLALELEESHHKV-ESQQKMITELEGQREMQRVALTHLTLDLEERSQ 1594
Query 64 QLTQLQSQFKQLNTDATALADRYSRLEKSCTDLKNRFQEILAERNELRVTKEKLQAQQRQ 123
+L SQ +L +T LA +L+ R QE+ ++R ++ ++LQ QQ Q
Sbjct 1595 ELQAQSSQLHELENHSTHLAK----------ELQERDQEVTSQRQQI----DELQKQQEQ 1640
Query 124 THQEV----QELQQDRDRLQKKNELAKSKVEAIIQRLSILGTSQDQHAQEI 170
Q + QEL ++R+Q + + + + + L + S + +QE+
Sbjct 1641 LAQALERKGQELVLQKERIQVLEDQRTLQTKILEEDLEQIKHSLRERSQEL 1691
Score = 41.6 bits (96), Expect = 1e-07
Identities = 44/197 (22%), Positives = 84/197 (43%), Gaps = 21/197 (11%)
Query 6 QRLQAHVGVLKTRLLHLESDNETLTQAKDESAAQHHSQ----------IVQKNGIITAKQ 55
Q LQ + + L + + ETL Q K ++ Q S + Q + + +Q
Sbjct 1791 QVLQGQLEEAQRDLAQRDHELETLRQEKQQTQDQEESMKLKTSALQAALEQAHATLKERQ 1850
Query 56 EEIDTLTEQLTQLQSQFKQLNTDATALADRYSRL-------EKSCTDLKNRF----QEIL 104
E++ EQ+ +LQ + + AL + L EK+ L+ R QE
Sbjct 1851 GELEEHREQVRRLQEELEVEGRQVRALEEVLGDLRAESREHEKAVLALQQRCAEQAQEHE 1910
Query 105 AERNELRVTKEKLQAQQRQTHQEVQELQQDRDRLQKKNELAKSKVEAIIQRLSILGTSQD 164
AE L+ + + QA + QE+ L+ + +++ E A S+ EA+ + LS +
Sbjct 1911 AEARTLQDSWLQAQATLTEQEQELAALRAENQYSRRQEEAAVSQAEALQEALSKAQAALQ 1970
Query 165 QHAQEIQQLADPTEEIQ 181
+ Q + + A+ + ++
Sbjct 1971 EKEQSLLEQAELSHTLE 1987
Score = 41.2 bits (95), Expect = 2e-07
Identities = 44/186 (24%), Positives = 78/186 (42%), Gaps = 17/186 (9%)
Query 3 EQLQRLQAHVGVLKTRLLHLESDNETLTQAKDESAAQHHSQIVQKNGIITAKQEEIDTLT 62
E+ + + L++ L L +L Q++ A + ++ A +E++
Sbjct 1291 EEKSKWEGRQNSLESELRDLHETAASL-QSRLRQAELQKMEAQNDRELLQASKEKLSAQV 1349
Query 63 EQLTQLQSQFKQLNTDATALADRYSRLEKSCTDLKNRFQE-------ILAERNELRVTKE 115
E L ++ Q DA A+ + R +S LKN E L E+ EL+V +
Sbjct 1350 EHLQACVAE-AQAQADAAAVLEEDLRTARSALKLKNEELESERERAQALQEQGELKVAQG 1408
Query 116 K-------LQAQQRQTHQ-EVQELQQDRDRLQKKNELAKSKVEAIIQRLSILGTSQDQHA 167
K L AQ + EV+ LQ + L+K+ E+ K+ +E + L D
Sbjct 1409 KALQENLALLAQTLSNREREVETLQAEVQELEKQREMQKAALELLSLDLKKRSREVDLQQ 1468
Query 168 QEIQQL 173
++IQ+L
Sbjct 1469 EQIQEL 1474
Score = 39.7 bits (91), Expect = 6e-07
Identities = 40/175 (23%), Positives = 77/175 (44%), Gaps = 11/175 (6%)
Query 8 LQAHVGVLKTRLLHLESDNETLTQAKDESAAQHHSQIVQKNGIITAKQEEIDTLTEQLTQ 67
L+A V L+ + L + NE L K E Q Q+ Q+N + ++ E + L +
Sbjct 588 LKAEVADLRAAAVKLGALNEALALDKVE-LNQQLLQLEQENQSLCSRVEAAEQLR---SA 643
Query 68 LQSQFKQLNTDATALADRYSRLEKSCTDLKNRFQEILAERNELRVTKEKLQAQQRQTHQE 127
LQ + AL ++ ++LE + E+ AE R KE+L+ + + H +
Sbjct 644 LQVDLAEAERRREALWEKKTQLETQLQKAEEAGAELQAELRGTREEKEELKDKLSEAHHQ 703
Query 128 -------VQELQQDRDRLQKKNELAKSKVEAIIQRLSILGTSQDQHAQEIQQLAD 175
+++L QD +R ++ A + EA+++ + L ++ Q L +
Sbjct 704 QETATAHLEQLHQDAERQEETLARAVQEKEALVRERAALEVRLQAVERDRQDLTE 758
Score = 39.7 bits (91), Expect = 6e-07
Identities = 47/183 (26%), Positives = 86/183 (47%), Gaps = 21/183 (11%)
Query 4 QLQRLQAHVGVLKTRLLHLESDNETLTQAKDESAAQHHSQIVQKNGIITAKQEEIDTLTE 63
QL+ + V +L+T L TQ + A+Q ++ Q I K++E + +
Sbjct 921 QLETEKERVSLLETLLR---------TQKELADASQQLERLRQDMKIQKLKEQETTGMLQ 971
Query 64 QLTQLQSQFKQLNTDATALADRYSRLEKSCTDLKNRFQEIL----AERNELRVTKEKLQA 119
QLQ ++L A D + +K DL+ + ++++ A + R+ KE+++
Sbjct 972 --AQLQETQQELKEAAQQHRDDLAAFQKDKLDLQKQVEDLMSQLVAHDDSQRLVKEEIE- 1028
Query 120 QQRQTHQEVQELQQDRDRLQKKN-ELAKSKVEAIIQRLSILGTSQDQHAQEIQQLADPTE 178
++ + QE +Q++ L+K+N LA S VE +RL IL + QE+ L +
Sbjct 1029 EKVKVAQECSRIQKE---LEKENASLALSLVEK-EKRLLILQEADSVRQQELSSLRQDIQ 1084
Query 179 EIQ 181
E Q
Sbjct 1085 EAQ 1087
Score = 39.3 bits (90), Expect = 9e-07
Identities = 47/192 (24%), Positives = 80/192 (42%), Gaps = 19/192 (10%)
Query 8 LQAHVGVLKTRLLHLESDNETLTQAKDESAAQHHSQIVQKNGIITAKQEEIDTLTEQLTQ 67
LQA L ++ HL++ QA+ ++AA + + K EE+++ E+
Sbjct 1338 LQASKEKLSAQVEHLQACVAE-AQAQADAAAVLEEDLRTARSALKLKNEELESERERAQA 1396
Query 68 LQ-------SQFKQLNTDATALADRYSRLEKSCTDLKNRFQEILAERNELRVTKEKLQAQ 120
LQ +Q K L + LA S E+ L+ QE+ +R + E L
Sbjct 1397 LQEQGELKVAQGKALQENLALLAQTLSNREREVETLQAEVQELEKQREMQKAALELLSLD 1456
Query 121 QRQTHQEV-------QELQQDRDRLQKKNELAKSKVEAI-IQRLSILGTSQDQHAQEI-- 170
++ +EV QEL+Q R L+ + + + + +QR I D+ AQ
Sbjct 1457 LKKRSREVDLQQEQIQELEQCRSVLEHLPMAVQEREQKLSVQRDQIRELENDREAQRSVL 1516
Query 171 -QQLADPTEEIQ 181
QL D ++ Q
Sbjct 1517 EHQLLDLEQKAQ 1528
Score = 37.4 bits (85), Expect = 4e-06
Identities = 45/196 (23%), Positives = 87/196 (44%), Gaps = 21/196 (11%)
Query 3 EQLQRLQAHVGVLKTRLLHLESDNETLTQAKDESAAQHHSQIVQKNGI------ITAKQE 56
EQ+Q L+ VL+ + ++ + L+ +D+ + + Q++ + + K +
Sbjct 1469 EQIQELEQCRSVLEHLPMAVQEREQKLSVQRDQIRELENDREAQRSVLEHQLLDLEQKAQ 1528
Query 57 EIDTLTEQLTQLQSQFKQLNTDATALADRYSRLE---KSCTDLKNR--FQEILAERN--E 109
I++ Q+ L+ Q L A L + + ++E K T+L+ + Q + +
Sbjct 1529 VIESQRGQIQDLKKQLGTLECLALELEESHHKVESQQKMITELEGQREMQRVALTHLTLD 1588
Query 110 LRVTKEKLQAQQRQTHQEVQELQQDRDRLQKKNELAKSKVEAIIQRLSILGTSQDQHAQE 169
L ++LQAQ Q H EL+ L K+ + +V + Q++ L Q+Q AQ
Sbjct 1589 LEERSQELQAQSSQLH----ELENHSTHLAKELQERDQEVTSQRQQIDELQKQQEQLAQA 1644
Query 170 I----QQLADPTEEIQ 181
+ Q+L E IQ
Sbjct 1645 LERKGQELVLQKERIQ 1660
Score = 35.0 bits (79), Expect = 2e-05
Identities = 41/174 (24%), Positives = 70/174 (40%), Gaps = 8/174 (5%)
Query 4 QLQRLQAHVGVLKTRLLHLESDNETLTQAKDESAAQHHSQ--IVQKNGIITAKQEEIDTL 61
Q Q LQ H V + L E L Q +++ A+ + I +K + +QEE L
Sbjct 2019 QAQALQHHE-VTQHLQQELCQKKEELRQLLEKAGARRSQENGIQEKQSLEQERQEETRRL 2077
Query 62 TEQLTQLQSQFKQLNTDATALADRYSRLEKSCTDLKNRFQEILAERNELRVTKEKLQAQQ 121
E L +LQ Q + L + S ++ K Q + A++ E+LQ
Sbjct 2078 LESLKELQLTVAQREEEILMLREASSPRHRALPAEKPALQPLPAQQE-----LERLQTAL 2132
Query 122 RQTHQEVQELQQDRDRLQKKNELAKSKVEAIIQRLSILGTSQDQHAQEIQQLAD 175
RQT E ++ L +K+ + ++ + L S + E Q+L +
Sbjct 2133 RQTEAREIEWREKAQDLALSLAQSKASISSLQEITMFLQASVLERESEQQRLQE 2186
Score = 33.5 bits (75), Expect = 7e-05
Identities = 46/211 (22%), Positives = 87/211 (41%), Gaps = 38/211 (18%)
Query 3 EQLQRLQAHVGVLKTRLLHLES----------DNETLT----QAKDESAAQHHSQIVQKN 48
E+ QR ++ V V LH+E D E LT +A+DE + +++
Sbjct 104 EEQQRCESLVEVNTELRLHMEKADVVNKALQEDVEKLTVDWSRARDELVRKESQWRMEQE 163
Query 49 ---GIITAKQEEIDTLTEQLTQLQSQFKQLNT----DATALADRYSRLEKS----CTDLK 97
G + + + L ++ + F ++ + D T L ++RL S C L
Sbjct 164 FFKGYLRGEHGRLLNLWREVVTFRRHFLKMKSATDRDLTELKAEHARLSGSLLTCCLRLT 223
Query 98 NRFQEILA---------ERNELRVTKEKLQAQQRQTHQEVQELQQDRDRLQKKNELAKSK 148
R Q + E L + K QA +++ H++ QEL Q L+ +L K++
Sbjct 224 LRAQSRESSGSGRTEESEPARLLLLVAKTQALEKEAHEKSQELMQ----LKSHGDLEKAE 279
Query 149 VEAIIQRLSILGTSQDQHAQEIQQLADPTEE 179
++ + LS L T + ++ +++ E
Sbjct 280 LQDRVTELSALLTQSQKQNEDYEKMVKALRE 310
Score = 33.1 bits (74), Expect = 9e-05
Identities = 43/211 (20%), Positives = 84/211 (40%), Gaps = 43/211 (20%)
Query 4 QLQRLQAHVGVLKTRLLHLESDNETLTQAKDESAAQHHSQIVQKNGI---ITAKQEEIDT 60
Q + LQ ++ +L L + E + ETL E Q Q + + + E+D
Sbjct 1407 QGKALQENLALLAQTLSNREREVETLQAEVQELEKQREMQKAALELLSLDLKKRSREVDL 1466
Query 61 LTEQLTQLQ------------------------SQFKQLNTDATALADRYSRLEKSCTDL 96
EQ+ +L+ Q ++L D A + S LE DL
Sbjct 1467 QQEQIQELEQCRSVLEHLPMAVQEREQKLSVQRDQIRELENDREA---QRSVLEHQLLDL 1523
Query 97 KNRFQEILAERNELRVTK------EKLQAQQRQTHQEVQELQQDRDRLQKKNELAKSKVE 150
+ + Q I ++R +++ K E L + ++H +V+ Q+ L+ + E+ +
Sbjct 1524 EQKAQVIESQRGQIQDLKKQLGTLECLALELEESHHKVESQQKMITELEGQREMQR---- 1579
Query 151 AIIQRLSILGTSQDQHAQEIQQLADPTEEIQ 181
L+ L ++ +QE+Q + E++
Sbjct 1580 ---VALTHLTLDLEERSQELQAQSSQLHELE 1607
Score = 30.4 bits (67), Expect = 7e-04
Identities = 34/182 (19%), Positives = 82/182 (45%), Gaps = 12/182 (7%)
Query 3 EQLQRLQAHVGVLKTRLLHLESDNETLTQAKDESAAQHHSQIVQKNGIITAKQEEIDTLT 62
+ ++ L+ + +L+T L +L++ E Q+++ A EE DT+T
Sbjct 303 KMVKALRETMEILETNHAELMEHEASLSRNAQEEKLSLQ-QVIKAITQALASVEEEDTVT 361
Query 63 EQL---TQLQS------QFKQLNTDA--TALADRYSRLEKSCTDLKNRFQEILAERNELR 111
+ LQS QF + D T + +R +++ DL+ + + L+
Sbjct 362 QSSGHEDSLQSDCNGLSQFDPQDPDRALTLVQSVLTRRQQAVQDLRQQLSGCQEAMSFLQ 421
Query 112 VTKEKLQAQQRQTHQEVQELQQDRDRLQKKNELAKSKVEAIIQRLSILGTSQDQHAQEIQ 171
++ + + R +++Q+L +RD L + + +V+++ + +L ++ + Q+++
Sbjct 422 QQHDQWEEEGRALREKLQKLTGERDALAGQTVGLQGEVDSLSRERELLQKARGELQQQLE 481
Query 172 QL 173
L
Sbjct 482 VL 483
Score = 30.4 bits (67), Expect = 7e-04
Identities = 32/174 (18%), Positives = 75/174 (43%), Gaps = 23/174 (13%)
Query 2 LEQLQRLQAHVGVLKTRLLHLESDNETLTQ------AKDESAAQHHSQIVQKNGIITAKQ 55
+++ + L L+ RL +E D + LT+ + E + + Q+N +I +
Sbjct 729 VQEKEALVRERAALEVRLQAVERDRQDLTEHVLGLRSAKEQLESNLFEAQQQNSVIQVTK 788
Query 56 EEIDTLTEQLTQ----LQSQFK----QLNTDATALADRYSRLEKSCTDLKNRFQEIL--- 104
+++ + + Q +Q + K +L+ + T + + + + Q L
Sbjct 789 GQLEVQIQTIIQAKEVIQGEVKCLKLELDAERTRAEQEWDAVARQLAQAEQEGQASLERQ 848
Query 105 --AERNELRVTKEKLQAQQRQTHQE----VQELQQDRDRLQKKNELAKSKVEAI 152
A E+ +EK + ++ QE ++ L+++R L+ K ++++EAI
Sbjct 849 KVAHEEEVNRLQEKWEKERSWLQQELDKTLETLERERAELETKLREQQTEMEAI 902
Score = 28.9 bits (63), Expect = 0.002
Identities = 32/158 (20%), Positives = 71/158 (45%), Gaps = 15/158 (9%)
Query 3 EQLQRLQAHVGVLKTRLLHLESDNETLTQAKDESAA-----QHHSQIVQKNGIITAKQEE 57
++L+RLQ + + R + + L + +S A Q + +Q + + ++ E
Sbjct 2123 QELERLQTALRQTEAREIEWREKAQDLALSLAQSKASISSLQEITMFLQAS--VLERESE 2180
Query 58 IDTLTEQLTQLQSQFKQLNTD---ATALADRYSRLEKSCTDLKNRFQEILAERNELRVTK 114
L E+L + ++ + +T+ AD+ ++ + ++ E+ E + K
Sbjct 2181 QQRLQEELVLSRQALEEQQSGGPHSTSRADQGPKVGQG-----SQSGEVETEPSPGVEEK 2235
Query 115 EKLQAQQRQTHQEVQELQQDRDRLQKKNELAKSKVEAI 152
E+L + + Q V EL+ DR +LQ N ++ +E +
Sbjct 2236 ERLTQRLERLQQAVAELEVDRSKLQCHNAQLRTALEQV 2273
Score = 28.5 bits (62), Expect = 0.003
Identities = 36/179 (20%), Positives = 73/179 (41%), Gaps = 26/179 (15%)
Query 3 EQLQRLQAHVGVLKTRLLHLESDNETLTQAKDESAAQHHSQIVQKNGIITAKQEEIDTLT 62
++LQ + + L+ HL + Q +D+ +T+++++ID L
Sbjct 1594 QELQAQSSQLHELENHSTHLAKE----LQERDQE--------------VTSQRQQIDELQ 1635
Query 63 EQLTQLQSQFKQLNTDATALADRYSRLEKSCTDLKNRFQEILAE-RNELRVTKEKLQAQQ 121
+Q QL ++ + +R LE T +E L + ++ LR ++L +Q
Sbjct 1636 KQQEQLAQALERKGQELVLQKERIQVLEDQRTLQTKILEEDLEQIKHSLRERSQELASQW 1695
Query 122 RQTHQEVQE----LQQDRDRLQKKNELAKSK---VEAIIQRLSILGTSQDQHAQEIQQL 173
+ H+ + + R L+ + + K VE +R+ L Q Q++Q L
Sbjct 1696 QLVHERADDGKSPSKGQRGSLEHLKLILRDKEKEVECQQERIQELQGHMGQLEQQLQGL 1754
Score = 28.5 bits (62), Expect = 0.003
Identities = 31/150 (21%), Positives = 54/150 (36%), Gaps = 5/150 (3%)
Query 37 AAQHHSQIVQKNGIITAKQEEIDTLTEQLTQLQSQFKQLNTDATALADRYSRLEKSCTDL 96
A QHH + K+EE+ L E+ +SQ + + +R + L
Sbjct 2022 ALQHHEVTQHLQQELCQKKEELRQLLEKAGARRSQENGIQEKQSLEQERQEETRRLLESL 2081
Query 97 KNRFQEILAERNELRVTKEKLQAQQRQTHQEVQEL-----QQDRDRLQKKNELAKSKVEA 151
K + E+ + +E + R E L QQ+ +RLQ +++
Sbjct 2082 KELQLTVAQREEEILMLREASSPRHRALPAEKPALQPLPAQQELERLQTALRQTEAREIE 2141
Query 152 IIQRLSILGTSQDQHAQEIQQLADPTEEIQ 181
++ L S Q I L + T +Q
Sbjct 2142 WREKAQDLALSLAQSKASISSLQEITMFLQ 2171
Score = 27.3 bits (59), Expect = 0.007
Identities = 48/200 (24%), Positives = 83/200 (42%), Gaps = 27/200 (14%)
Query 4 QLQRL--QAHVGVLKTRLLHLESD-NETLTQAKDESAAQHH-------------SQIVQK 47
++Q+L Q G+L+ +L + + E Q +D+ AA SQ+V
Sbjct 957 KIQKLKEQETTGMLQAQLQETQQELKEAAQQHRDDLAAFQKDKLDLQKQVEDLMSQLVAH 1016
Query 48 NGIITAKQEEIDTLTEQLTQLQSQFKQLNTDATALADRYSRLEKSCTDLKN----RFQEI 103
+ +EEI+ + + K+L + +LA EK L+ R QE+
Sbjct 1017 DDSQRLVKEEIEEKVKVAQECSRIQKELEKENASLALSLVEKEKRLLILQEADSVRQQEL 1076
Query 104 LAERNELRVTKE---KLQAQQRQTHQEVQELQQD--RDRLQKKNELAKSKVEAIIQRLSI 158
+ R +++ +E +L Q QEV+E + D Q EL S+V Q+L
Sbjct 1077 SSLRQDIQEAQEGQRELGVQVELLRQEVKEKEADFVAREAQLLEELEASRVAE--QQLRA 1134
Query 159 LGTSQDQHAQEIQQLADPTE 178
+Q+ A ++Q TE
Sbjct 1135 SLWAQEAKATQLQLQLRSTE 1154
Score = 24.3 bits (51), Expect = 0.070
Identities = 18/91 (20%), Positives = 41/91 (45%), Gaps = 15/91 (16%)
Query 82 LADRYSRLEKSCTDLKNRFQEILAERNELRVTKEKLQAQQRQTHQEVQELQQDRDRLQKK 141
L R RL+++ EL V + KLQ Q +++++++R +L K+
Sbjct 2238 LTQRLERLQQAVA--------------ELEVDRSKLQCHNAQLRTALEQVERERRKL-KR 2282
Query 142 NELAKSKVEAIIQRLSILGTSQDQHAQEIQQ 172
+ + S+ ++ R ++ + Q + Q+
Sbjct 2283 DSVRASRAGSLEARETMTSSPTQQDGRGSQR 2313
Score = 22.7 bits (47), Expect = 0.22
Identities = 28/148 (19%), Positives = 56/148 (38%), Gaps = 17/148 (11%)
Query 3 EQLQRLQAHVGVLKTRLLHLESDNETLTQAKDESAAQHHSQIVQKNGIITAKQEEIDTLT 62
E+L++L G +++ ++ + ++L Q + E + + + + ++EEI L
Sbjct 2041 EELRQLLEKAGARRSQENGIQ-EKQSLEQERQEETRRLLESLKELQLTVAQREEEILMLR 2099
Query 63 E----------------QLTQLQSQFKQLNTDATALADRYSRLEKSCTDLKNRFQEILAE 106
E Q Q + ++L T R + DL + A
Sbjct 2100 EASSPRHRALPAEKPALQPLPAQQELERLQTALRQTEAREIEWREKAQDLALSLAQSKAS 2159
Query 107 RNELRVTKEKLQAQQRQTHQEVQELQQD 134
+ L+ LQA + E Q LQ++
Sbjct 2160 ISSLQEITMFLQASVLERESEQQRLQEE 2187
Score = 19.6 bits (39), Expect = 2.1
Identities = 22/96 (23%), Positives = 41/96 (43%), Gaps = 6/96 (6%)
Query 61 LTEQLTQLQSQFKQLNTDATALADRYSRLEKSCTDLKNRFQ-EILAERNELRVTKEKLQA 119
L Q+ LQ Q + + +K L + Q ++L R+ + +++L+A
Sbjct 19 LEGQVLALQQQMAENQAASWRKLKNSQEAQKRQATLVRKLQAKVLQYRSWCQDLEKRLEA 78
Query 120 Q-----QRQTHQEVQELQQDRDRLQKKNELAKSKVE 150
QR E L+Q RL+++ + +S VE
Sbjct 79 TGGLIPQRWESVEEPNLEQLLIRLEEEQQRCESLVE 114
Score = 18.1 bits (35), Expect = 6.5
Identities = 8/23 (35%), Positives = 12/23 (52%), Gaps = 0/23 (0%)
Query 7 RLQAHVGVLKTRLLHLESDNETL 29
+LQ H L+T L +E + L
Sbjct 2258 KLQCHNAQLRTALEQVERERRKL 2280
>P40414 Tropomyosin-2 [Saccharomyces cerevisiae (strain ATCC 204508
/ S288c)]
Length=161
Score = 49.3 bits (116), Expect = 9e-11
Identities = 38/151 (25%), Positives = 69/151 (46%), Gaps = 4/151 (3%)
Query 16 KTRLLHLESDN--ETLTQAKDESAAQHHSQIVQKNGI--ITAKQEEIDTLTEQLTQLQSQ 71
K L LES++ E + +++ S ++N I ++AK E++D+ E+L S
Sbjct 7 KLNSLKLESESWQEKYEELREQLKELEQSNTEKENEIKSLSAKNEQLDSEVEKLESQLSD 66
Query 72 FKQLNTDATALADRYSRLEKSCTDLKNRFQEILAERNELRVTKEKLQAQQRQTHQEVQEL 131
KQL D+ L K DL+ + ++ A+ E ++ Q + + L
Sbjct 67 TKQLAEDSNNLRSNNENYTKKNQDLEQQLEDSEAKLKEAMDKLKEADLNSEQMGRRIVAL 126
Query 132 QQDRDRLQKKNELAKSKVEAIIQRLSILGTS 162
+++RD +KK E +SK E + L + S
Sbjct 127 EEERDEWEKKCEEFQSKYEEAQKELDEIANS 157
Score = 32.0 bits (71), Expect = 1e-04
Identities = 27/134 (20%), Positives = 61/134 (46%), Gaps = 11/134 (8%)
Query 55 QEEIDTLTEQLTQLQSQFKQLNT----DATALADRYSRLEKSCTDLKNRF---QEILAER 107
QE+ + L EQL +L +Q NT + +L+ + +L+ L+++ +++ +
Sbjct 19 QEKYEELREQLKEL----EQSNTEKENEIKSLSAKNEQLDSEVEKLESQLSDTKQLAEDS 74
Query 108 NELRVTKEKLQAQQRQTHQEVQELQQDRDRLQKKNELAKSKVEAIIQRLSILGTSQDQHA 167
N LR E + + Q++++ + K + A E + +R+ L +D+
Sbjct 75 NNLRSNNENYTKKNQDLEQQLEDSEAKLKEAMDKLKEADLNSEQMGRRIVALEEERDEWE 134
Query 168 QEIQQLADPTEEIQ 181
++ ++ EE Q
Sbjct 135 KKCEEFQSKYEEAQ 148
>P56536 Kinesin heavy chain isoform 5C [Rattus norvegicus]
Length=955
Score = 50.8 bits (120), Expect = 1e-10
Identities = 44/170 (26%), Positives = 88/170 (52%), Gaps = 15/170 (9%)
Query 15 LKTRLLHLESDNETLTQAKDESAAQHHSQIV---QKNGIITAKQEEIDTLTEQLTQLQSQ 71
LK+ + HLE + L + ++ A QI QKN ID +T + + ++
Sbjct 356 LKSVIQHLEVE---LNRWRNGEAVPEDEQISAKDQKNLEPCDNTPIIDNITPVVDGISAE 412
Query 72 FKQLNTDATALADRYSRLEKSCTDLKNRFQEILAER-NELRVTKEKLQAQQRQTHQEVQE 130
++ + + T+L Y +L+ ++ + Q LAE+ + + +++L A R+ ++++QE
Sbjct 413 KEKYDEEITSL---YRQLDDKDDEINQQSQ--LAEKLKQQMLDQDELLASTRRDYEKIQE 467
Query 131 LQQDRDRLQKKNELAKSKVEAIIQRLSILGTSQDQHAQEIQQLADPTEEI 180
+ RLQ +NE AK +V+ ++Q L L + DQ +QE++ E++
Sbjct 468 ---ELTRLQIENEAAKDEVKEVLQALEELAVNYDQKSQEVEDKTRANEQL 514
Score = 37.7 bits (86), Expect = 3e-06
Identities = 35/198 (18%), Positives = 90/198 (45%), Gaps = 21/198 (11%)
Query 3 EQLQRLQAHVGVLKTRLLHLESDNETLTQAKDESAAQHHS---QIVQKNGIITAKQEEID 59
E+ + ++ +K+ + L + ++ L A+ +S + ++ ++ +I+ + +I
Sbjct 581 EEFTMARLYISKMKSEVKSLVNRSKQLESAQTDSNRKMNASERELAACQLLISQHEAKIK 640
Query 60 TLTEQLTQLQSQFKQLNTDATALADRYSRL-------EKSCTDLKNRFQEILAERNELRV 112
+LT+ + ++ + +QL +L++ ++L E S D + L + E++
Sbjct 641 SLTDYMQNMEQKRRQLEESQDSLSEELAKLRAQEKMHEVSFQDKEKEHLTRLQDAEEVKK 700
Query 113 TKEKLQAQQRQTHQ--------EVQELQQDRDR---LQKKNELAKSKVEAIIQRLSILGT 161
E+ R+ HQ E++E Q+ D L +K +L + ++ + +L I
Sbjct 701 ALEQQMESHREAHQKQLSRLRDEIEEKQRIIDEIRDLNQKLQLEQERLSSDYNKLKIEDQ 760
Query 162 SQDQHAQEIQQLADPTEE 179
++ +++ L D E+
Sbjct 761 EREVKLEKLLLLNDKREQ 778
Score = 32.3 bits (72), Expect = 2e-04
Identities = 26/99 (26%), Positives = 41/99 (41%), Gaps = 17/99 (17%)
Query 53 AKQEEIDTLTEQLTQLQSQFKQLNTDATALADRYSRLEKSCTDLKNRFQEILAERNELRV 112
A++++I L L QL KQL D L +LEK LR
Sbjct 828 AQKQKISFLENNLEQLTKVHKQLVRDNADLRCELPKLEK-----------------RLRA 870
Query 113 TKEKLQAQQRQTHQEVQELQQDRDRLQKKNELAKSKVEA 151
T E+++A + + + +DR R Q++ + K V A
Sbjct 871 TAERVKALESALKEAKENAMRDRKRYQQEVDRIKEAVRA 909
Score = 26.9 bits (58), Expect = 0.009
Identities = 41/203 (20%), Positives = 82/203 (40%), Gaps = 30/203 (15%)
Query 3 EQLQRLQAHVGVLKTRLLHLESDNETLT--------QAKDESAA--QHHSQIVQKNGIIT 52
E+L RLQ K + + E L + +D++ A Q ++ QK +T
Sbjct 467 EELTRLQIENEAAKDEVKEVLQALEELAVNYDQKSQEVEDKTRANEQLTDELAQKTTTLT 526
Query 53 AKQEEIDTL-----------TEQLTQLQSQFKQL-----NTDATALADRYSRLEKSCTDL 96
Q E+ L TE L L ++ D LAD +E+ T
Sbjct 527 TTQRELSQLQELSNHQKKRATEILNLLLKDLGEIGGIIGTNDVKTLADVNGVIEEEFTMA 586
Query 97 KNRFQEILAERNELRVTKEKLQAQQRQTHQEVQELQQDRDRLQKKNELAKSKVEAIIQRL 156
+ ++ +E L ++L++ Q +++++ +++ Q L S+ EA I+ L
Sbjct 587 RLYISKMKSEVKSLVNRSKQLESAQTDSNRKMNASERELAACQ----LLISQHEAKIKSL 642
Query 157 SILGTSQDQHAQEIQQLADPTEE 179
+ + +Q +++++ D E
Sbjct 643 TDYMQNMEQKRRQLEESQDSLSE 665
Score = 25.8 bits (55), Expect = 0.022
Identities = 36/190 (19%), Positives = 76/190 (40%), Gaps = 27/190 (14%)
Query 15 LKTRLLHLESDNET-------LTQAKDESAAQHHSQIVQKNGIITAKQEEIDTLTEQLTQ 67
++ L L+ +NE + QA +E A + QK+ + K + LT++L Q
Sbjct 465 IQEELTRLQIENEAAKDEVKEVLQALEELAVNYD----QKSQEVEDKTRANEQLTDELAQ 520
Query 68 LQSQFKQLNTDATALADRYSRLEKSCTDLKNRFQEILAE------RNELR-------VTK 114
+ + + L + + +K T++ N + L E N+++ V +
Sbjct 521 KTTTLTTTQRELSQLQELSNHQKKRATEILNLLLKDLGEIGGIIGTNDVKTLADVNGVIE 580
Query 115 EKLQAQQ---RQTHQEVQELQQDRDRLQKKNELAKSKVEAIIQRLSILGTSQDQHAQEIQ 171
E+ + + EV+ L +L+ + K+ A + L+ QH +I+
Sbjct 581 EEFTMARLYISKMKSEVKSLVNRSKQLESAQTDSNRKMNASERELAACQLLISQHEAKIK 640
Query 172 QLADPTEEIQ 181
L D + ++
Sbjct 641 SLTDYMQNME 650
Score = 21.2 bits (43), Expect = 0.66
Identities = 23/90 (26%), Positives = 32/90 (36%), Gaps = 15/90 (17%)
Query 24 SDNETLTQAKDESAAQHHSQIVQKNG---------IITAKQEEIDTLTE-----QLTQLQ 69
S E + DE A H + N +I KQE ++T + L L
Sbjct 175 SSPEEVMDVIDEGKANRHVAVTNMNEHSSRSHSIFLINIKQENVETEKKLSGKLYLVDLA 234
Query 70 SQFKQLNTDAT-ALADRYSRLEKSCTDLKN 98
K T A A+ D + KS + L N
Sbjct 235 GSEKVSKTGAEGAVLDEAKNINKSLSALGN 264
>P28738 Kinesin heavy chain isoform 5C [Mus musculus]
Length=956
Score = 50.4 bits (119), Expect = 1e-10
Identities = 43/170 (25%), Positives = 88/170 (52%), Gaps = 15/170 (9%)
Query 15 LKTRLLHLESDNETLTQAKDESAAQHHSQIVQKNGIITAKQEE---IDTLTEQLTQLQSQ 71
LK+ L HLE + L + ++ A QI K+ + ID +T + + ++
Sbjct 356 LKSVLQHLEME---LNRWRNGEAVPEDEQISAKDQKSLEPCDNTPIIDNITPVVDGISAE 412
Query 72 FKQLNTDATALADRYSRLEKSCTDLKNRFQEILAER-NELRVTKEKLQAQQRQTHQEVQE 130
++ + + T+L Y +L+ ++ + Q LAE+ + + +++L A R+ ++++QE
Sbjct 413 KEKYDEEITSL---YRQLDDKDDEINQQSQ--LAEKLKQQMLDQDELLASTRRDYEKIQE 467
Query 131 LQQDRDRLQKKNELAKSKVEAIIQRLSILGTSQDQHAQEIQQLADPTEEI 180
+ RLQ +NE AK +V+ ++Q L L + DQ +QE++ E++
Sbjct 468 ---ELTRLQIENEAAKDEVKEVLQALEELAVNYDQKSQEVEDKTRANEQL 514
Score = 37.0 bits (84), Expect = 5e-06
Identities = 35/198 (18%), Positives = 90/198 (45%), Gaps = 21/198 (11%)
Query 3 EQLQRLQAHVGVLKTRLLHLESDNETLTQAKDESAAQHHS---QIVQKNGIITAKQEEID 59
E+ + ++ +K+ + L + ++ L A+ +S + ++ ++ +I+ + +I
Sbjct 581 EEFTMARLYISKMKSEVKSLVNRSKQLESAQMDSNRKMNASERELAACQLLISQHEAKIK 640
Query 60 TLTEQLTQLQSQFKQLNTDATALADRYSRL-------EKSCTDLKNRFQEILAERNELRV 112
+LT+ + ++ + +QL +L++ ++L E S D + L + E++
Sbjct 641 SLTDYMQNMEQKRRQLEESQDSLSEELAKLRAQEKMHEVSFQDKEKEHLTRLQDAEEVKK 700
Query 113 TKEKLQAQQRQTHQ--------EVQELQQDRDR---LQKKNELAKSKVEAIIQRLSILGT 161
E+ R+ HQ E++E Q+ D L +K +L + ++ + +L I
Sbjct 701 ALEQQMESHREAHQKQLSRLRDEIEEKQRIIDEIRDLNQKLQLEQERLSSDYNKLKIEDQ 760
Query 162 SQDQHAQEIQQLADPTEE 179
++ +++ L D E+
Sbjct 761 EREVKLEKLLLLNDKREQ 778
Score = 32.3 bits (72), Expect = 2e-04
Identities = 26/99 (26%), Positives = 41/99 (41%), Gaps = 17/99 (17%)
Query 53 AKQEEIDTLTEQLTQLQSQFKQLNTDATALADRYSRLEKSCTDLKNRFQEILAERNELRV 112
A++++I L L QL KQL D L +LEK LR
Sbjct 828 AQKQKISFLENNLEQLTKVHKQLVRDNADLRCELPKLEK-----------------RLRA 870
Query 113 TKEKLQAQQRQTHQEVQELQQDRDRLQKKNELAKSKVEA 151
T E+++A + + + +DR R Q++ + K V A
Sbjct 871 TAERVKALESALKEAKENAMRDRKRYQQEVDRIKEAVRA 909
Score = 26.9 bits (58), Expect = 0.009
Identities = 41/203 (20%), Positives = 82/203 (40%), Gaps = 30/203 (15%)
Query 3 EQLQRLQAHVGVLKTRLLHLESDNETLT--------QAKDESAA--QHHSQIVQKNGIIT 52
E+L RLQ K + + E L + +D++ A Q ++ QK +T
Sbjct 467 EELTRLQIENEAAKDEVKEVLQALEELAVNYDQKSQEVEDKTRANEQLTDELAQKTTTLT 526
Query 53 AKQEEIDTL-----------TEQLTQLQSQFKQL-----NTDATALADRYSRLEKSCTDL 96
Q E+ L TE L L ++ D LAD +E+ T
Sbjct 527 TTQRELSQLQELSNHQKKRATEILNLLLKDLGEIGGIIGTNDVKTLADVNGVIEEEFTMA 586
Query 97 KNRFQEILAERNELRVTKEKLQAQQRQTHQEVQELQQDRDRLQKKNELAKSKVEAIIQRL 156
+ ++ +E L ++L++ Q +++++ +++ Q L S+ EA I+ L
Sbjct 587 RLYISKMKSEVKSLVNRSKQLESAQMDSNRKMNASERELAACQ----LLISQHEAKIKSL 642
Query 157 SILGTSQDQHAQEIQQLADPTEE 179
+ + +Q +++++ D E
Sbjct 643 TDYMQNMEQKRRQLEESQDSLSE 665
Score = 25.4 bits (54), Expect = 0.029
Identities = 36/190 (19%), Positives = 76/190 (40%), Gaps = 27/190 (14%)
Query 15 LKTRLLHLESDNET-------LTQAKDESAAQHHSQIVQKNGIITAKQEEIDTLTEQLTQ 67
++ L L+ +NE + QA +E A + QK+ + K + LT++L Q
Sbjct 465 IQEELTRLQIENEAAKDEVKEVLQALEELAVNYD----QKSQEVEDKTRANEQLTDELAQ 520
Query 68 LQSQFKQLNTDATALADRYSRLEKSCTDLKNRFQEILAE------RNELR-------VTK 114
+ + + L + + +K T++ N + L E N+++ V +
Sbjct 521 KTTTLTTTQRELSQLQELSNHQKKRATEILNLLLKDLGEIGGIIGTNDVKTLADVNGVIE 580
Query 115 EKLQAQQ---RQTHQEVQELQQDRDRLQKKNELAKSKVEAIIQRLSILGTSQDQHAQEIQ 171
E+ + + EV+ L +L+ + K+ A + L+ QH +I+
Sbjct 581 EEFTMARLYISKMKSEVKSLVNRSKQLESAQMDSNRKMNASERELAACQLLISQHEAKIK 640
Query 172 QLADPTEEIQ 181
L D + ++
Sbjct 641 SLTDYMQNME 650
Score = 21.2 bits (43), Expect = 0.66
Identities = 23/90 (26%), Positives = 32/90 (36%), Gaps = 15/90 (17%)
Query 24 SDNETLTQAKDESAAQHHSQIVQKNG---------IITAKQEEIDTLTE-----QLTQLQ 69
S E + DE A H + N +I KQE ++T + L L
Sbjct 175 SSPEEVMDVIDEGKANRHVAVTNMNEHSSRSHSIFLINIKQENVETEKKLSGKLYLVDLA 234
Query 70 SQFKQLNTDAT-ALADRYSRLEKSCTDLKN 98
K T A A+ D + KS + L N
Sbjct 235 GSEKVSKTGAEGAVLDEAKNINKSLSALGN 264
>P21613 Kinesin heavy chain [Doryteuthis pealeii]
Length=967
Score = 49.7 bits (117), Expect = 2e-10
Identities = 29/95 (31%), Positives = 52/95 (55%), Gaps = 4/95 (4%)
Query 86 YSRLEKSCTDLKNRFQEILAERNELRVTKEKLQAQQRQTHQEVQELQQDRDRLQKKNELA 145
Y +L+ ++ N+ Q ++ + E + +E L AQ R+ ++ LQQD R+Q NE A
Sbjct 423 YQQLDDKDDEINNQSQ-LIEKLKEQMMEQEDLIAQSRRDYEN---LQQDMSRIQADNESA 478
Query 146 KSKVEAIIQRLSILGTSQDQHAQEIQQLADPTEEI 180
K +V+ ++Q L L + DQ +QE++ E +
Sbjct 479 KDEVKEVLQALEELAMNYDQKSQEVEDKNKENENL 513
Score = 38.9 bits (89), Expect = 1e-06
Identities = 31/152 (20%), Positives = 63/152 (41%), Gaps = 7/152 (5%)
Query 22 LESDNETLTQAKDESAAQHHSQIVQKNGIITAKQEEIDTLTEQLTQLQSQFKQLNTDATA 81
+ S NE +E + + Q+ K+ I + + I+ L EQ+ + + Q D
Sbjct 404 IASMNEGDRTQLEEERLKLYQQLDDKDDEINNQSQLIEKLKEQMMEQEDLIAQSRRDYEN 463
Query 82 LADRYSRLEKSCTDLKNRFQEILAERNELRVTKEKLQAQQRQTHQEVQELQQDRDRLQKK 141
L SR++ K+ +E+L EL + + Q QEV++ ++ + L ++
Sbjct 464 LQQDMSRIQADNESAKDEVKEVLQALEELAMNYD-------QKSQEVEDKNKENENLSEE 516
Query 142 NELAKSKVEAIIQRLSILGTSQDQHAQEIQQL 173
S + ++ L L S H + + +
Sbjct 517 LNQKLSTLNSLQNELDQLKDSSMHHRKRVTDM 548
Score = 36.6 bits (83), Expect = 6e-06
Identities = 31/156 (20%), Positives = 68/156 (44%), Gaps = 2/156 (1%)
Query 16 KTRLLHLESDNETLTQAKDESAAQHHSQIVQKNGIITAKQEEIDTLTEQLTQLQSQFKQL 75
K R+L D+ AK ++ Q H + + T++ E + E+ Q++ +Q
Sbjct 653 KKRMLEDNVDSLNEEYAKLKAQEQMHLAALSEREKETSQASETREVLEK--QMEMHREQH 710
Query 76 NTDATALADRYSRLEKSCTDLKNRFQEILAERNELRVTKEKLQAQQRQTHQEVQELQQDR 135
+L D S + + +LK+ Q + +L+ +KL+ ++ + ++ +L
Sbjct 711 QKQLQSLRDEISEKQATVDNLKDDNQRLSLALEKLQADYDKLKQEEVEKAAKLADLSLQI 770
Query 136 DRLQKKNELAKSKVEAIIQRLSILGTSQDQHAQEIQ 171
DR ++ + K E + + L L + Q++Q
Sbjct 771 DRREQAKQDLKGLEETVAKELQTLHNLRKLFVQDLQ 806
Score = 28.1 bits (61), Expect = 0.004
Identities = 39/190 (21%), Positives = 74/190 (39%), Gaps = 29/190 (15%)
Query 15 LKTRLLHLESDNET-------LTQAKDESAAQHHSQIVQKNGIITAKQEEIDTLTEQLTQ 67
L+ + +++DNE+ + QA +E A + QK+ + K +E + L+E+L Q
Sbjct 464 LQQDMSRIQADNESAKDEVKEVLQALEELAMNYD----QKSQEVEDKNKENENLSEELNQ 519
Query 68 LQSQFKQLNTDATALADRYSRLEKSCTDLKNRFQEIL-----------AERNELRVTKEK 116
S L + L D K TD+ + L AE + EK
Sbjct 520 KLSTLNSLQNELDQLKDSSMHHRKRVTDMMINLLKDLGDIGTIVGGNAAETKPTAGSGEK 579
Query 117 LQAQQR-------QTHQEVQELQQDRDRLQKKNELAKSKVEAIIQRLSILGTSQDQHAQE 169
++ + + EV+ L ++L+ + K+E + LS QH +
Sbjct 580 IEEEFTVARLYISKMKSEVKTLVSRNNQLENTQQDNFKKIETHEKDLSNCKLLIQQHEAK 639
Query 170 IQQLADPTEE 179
+ L + ++
Sbjct 640 MASLQEAIKD 649
Score = 28.1 bits (61), Expect = 0.004
Identities = 35/170 (21%), Positives = 73/170 (43%), Gaps = 20/170 (12%)
Query 5 LQRLQAHVGVLK-------TRLLHLESDNETLTQAKDESAAQHHSQIVQKNGIITAKQEE 57
L++LQA LK +L L + QAK + + + + ++
Sbjct 742 LEKLQADYDKLKQEEVEKAAKLADLSLQIDRREQAKQDLKGLEETVAKELQTLHNLRKLF 801
Query 58 IDTLTEQLTQLQSQFKQLNTDA---TALADRYSRLEKSCTDLKNRFQEILAERNELRVTK 114
+ L ++ + S+ ++ + D A + S LE + L ++++ + +LR
Sbjct 802 VQDLQNKVKKSCSKTEEEDEDTGGNAAQKQKISFLENNLEQLTKVHKQLVRDNADLRCEL 861
Query 115 EKLQAQQRQTHQEVQELQQD---------RDRLQKKNELAKSKVEAIIQR 155
KL+ + R T + V+ L+ RDR + ++E+ + K EA+ Q+
Sbjct 862 PKLEKRLRATMERVKSLESALKDAKEGAMRDRKRYQHEVDRIK-EAVRQK 910
Score = 27.7 bits (60), Expect = 0.005
Identities = 29/168 (17%), Positives = 77/168 (46%), Gaps = 19/168 (11%)
Query 3 EQLQRLQAHVGVLKTRLLHLESDNETLTQAKDESAAQHHSQIVQKNGIITAKQEEIDTLT 62
+QLQ L+ + + + +L+ DN+ L+ A ++ A + ++ Q+ AK ++
Sbjct 712 KQLQSLRDEISEKQATVDNLKDDNQRLSLALEKLQAD-YDKLKQEEVEKAAKLADLSLQI 770
Query 63 EQLTQLQSQFKQL------------NTDATALADRYSRLEKSCTDLKNRFQEI---LAER 107
++ Q + K L N + D ++++KSC+ + ++ A++
Sbjct 771 DRREQAKQDLKGLEETVAKELQTLHNLRKLFVQDLQNKVKKSCSKTEEEDEDTGGNAAQK 830
Query 108 NELRVTK---EKLQAQQRQTHQEVQELQQDRDRLQKKNELAKSKVEAI 152
++ + E+L +Q ++ +L+ + +L+K+ +V+++
Sbjct 831 QKISFLENNLEQLTKVHKQLVRDNADLRCELPKLEKRLRATMERVKSL 878
Score = 20.8 bits (42), Expect = 0.87
Identities = 26/104 (25%), Positives = 38/104 (37%), Gaps = 16/104 (15%)
Query 24 SDNETLTQAKDESAAQHHSQIVQKNG---------IITAKQEEIDTLTE-----QLTQLQ 69
S E + + DE H + N +I KQE ++T + L L
Sbjct 174 SSPEEVMEVIDEGKNNRHVAVTNMNEHSSRSHSVFLINVKQENVETQKKLSGKLYLVDLA 233
Query 70 SQFKQLNTDAT-ALADRYSRLEKSCTDLKNRFQEILAERNELRV 112
K T A A+ D + KS + L N LA+ N+ V
Sbjct 234 GSEKVSKTGAEGAVLDEAKNINKSLSALGNVI-SALADGNKSHV 276
Score = 18.1 bits (35), Expect = 6.3
Identities = 22/101 (22%), Positives = 44/101 (44%), Gaps = 12/101 (12%)
Query 90 EKSCTDLKNRFQEILAERNELRVTKEKLQAQ-QRQTHQEVQELQQDRDRLQKKNELAKSK 148
E + + K R+++ +L+ T KL+A+ QR + +++ D K++ A+S
Sbjct 335 ELTADEWKRRYEKEKERVTKLKATMAKLEAELQRWRTGQAVSVEEQVDL--KEDVPAESP 392
Query 149 VEAIIQRLSILGTS---------QDQHAQEIQQLADPTEEI 180
+ L S +++ + QQL D +EI
Sbjct 393 ATSTTSLAGGLIASMNEGDRTQLEEERLKLYQQLDDKDDEI 433
>P05659 Myosin-2 heavy chain, non muscle [Acanthamoeba castellanii]
Length=1509
Score = 43.5 bits (101), Expect = 3e-08
Identities = 46/199 (23%), Positives = 87/199 (44%), Gaps = 34/199 (17%)
Query 1 MLEQLQRLQAHVGVLKTRLLHLESDNETLTQAK--------------DESAAQHHSQIVQ 46
+LEQ ++L+A G LK L E + + L +AK ++ AA H S +
Sbjct 945 ILEQKRKLEAEKGELKASLEEEERNRKALQEAKTKVESERNELQDKYEDEAAAHDSLKKK 1004
Query 47 KNGIITAKQEEIDTLT--EQLTQ-LQSQFKQLNTDATALADRYS-------RLEKSCTDL 96
+ + +E D L E +++ L+S+ K A + + +LEK+ L
Sbjct 1005 EEDLSRELRETKDALADAENISETLRSKLKNTERGADDVRNELDDVTATKLQLEKTKKSL 1064
Query 97 KNRFQEILAERNELRVTKEKLQAQQRQTHQEVQELQQDRDRLQKKNELAKSKVEAIIQRL 156
+ + A+ E + KE ++ +Q Q++++ + + D L+ K A+
Sbjct 1065 EEELAQTRAQLEEEKSGKEAASSKAKQLGQQLEDARSEVDSLKSKLSAAEKS-------- 1116
Query 157 SILGTSQDQHAQEIQQLAD 175
L T++DQ+ +QL D
Sbjct 1117 --LKTAKDQNRDLDEQLED 1133
Score = 42.7 bits (99), Expect = 6e-08
Identities = 26/97 (27%), Positives = 51/97 (53%), Gaps = 4/97 (4%)
Query 55 QEEIDTLTEQLTQLQSQFKQLNTDATALADRYSRLEKSCTDLKNRFQEILAERNELRVTK 114
+E+ D L + L L+ + L + L + + L+K L+ QE + N++ K
Sbjct 890 EEDADKLEKDLAALKLKILDLEGEKADLEEDNALLQKKVAGLEEELQEETSASNDILEQK 949
Query 115 EKLQAQQRQTHQEVQELQQDRDRLQKKNELAKSKVEA 151
KL+A++ + ++E +++R LQ+ AK+KVE+
Sbjct 950 RKLEAEKGELKASLEEEERNRKALQE----AKTKVES 982
Score = 42.4 bits (98), Expect = 8e-08
Identities = 28/140 (20%), Positives = 65/140 (46%), Gaps = 3/140 (2%)
Query 42 SQIVQKNGIITAKQEEIDTLTEQLTQLQSQFKQLNTDATALADRYSRLEKSCTDLKNRFQ 101
S++ ++A ++ + T +Q L Q + T + + LE T+L+++
Sbjct 1101 SEVDSLKSKLSAAEKSLKTAKDQNRDLDEQLEDERTVRANVDKQKKALEAKLTELEDQVT 1160
Query 102 EILAERNELRVTKEKLQAQQRQTHQEVQELQQDRDRLQKKNELAKSKVEAIIQRLSILGT 161
+ ++N + L+ Q +T + ++E + RL+K+ K+ ++ + Q + L
Sbjct 1161 ALDGQKNAAAAQAKTLKTQVDETKRRLEEAEASAARLEKER---KNALDEVAQLTADLDA 1217
Query 162 SQDQHAQEIQQLADPTEEIQ 181
+D AQ+ ++L E+Q
Sbjct 1218 ERDSGAQQRRKLNTRISELQ 1237
Score = 38.1 bits (87), Expect = 2e-06
Identities = 46/203 (23%), Positives = 87/203 (43%), Gaps = 30/203 (15%)
Query 3 EQLQRLQAHVGVLKTRLLHLESDNETLTQAKDESAAQHHSQIVQKNGIITAKQEEIDTLT 62
+QL+ ++ V LK++L E ++L AKD++ Q+ + + ++ L
Sbjct 1094 QQLEDARSEVDSLKSKLSAAE---KSLKTAKDQNR-DLDEQLEDERTVRANVDKQKKALE 1149
Query 63 EQLTQLQSQFKQLNTDATALADRYSRLEKSCTDLKNRFQEILAERNELRVTKEKLQA--- 119
+LT+L+ Q L+ A A + L+ + K R +E AE + R+ KE+ A
Sbjct 1150 AKLTELEDQVTALDGQKNAAAAQAKTLKTQVDETKRRLEE--AEASAARLEKERKNALDE 1207
Query 120 -----------------QQRQTHQEVQELQQDRDRLQKKNELAKSKV---EAIIQRL-SI 158
Q+R+ + + ELQ + + K + +V E ++RL
Sbjct 1208 VAQLTADLDAERDSGAQQRRKLNTRISELQSELENAPKTGGASSEEVKRLEGELERLEEE 1267
Query 159 LGTSQDQHAQEIQQLADPTEEIQ 181
L T+Q+ A + L E++
Sbjct 1268 LLTAQEARAAAEKNLDKANLELE 1290
Score = 37.7 bits (86), Expect = 3e-06
Identities = 44/193 (23%), Positives = 89/193 (46%), Gaps = 32/193 (17%)
Query 3 EQLQRLQAHVGVLKTRLL-----------HLESDNETLTQAKDES--AAQHHSQIVQKNG 49
E+++RL+ + L+ LL +L+ N L + + E+ AA+ + ++V+ N
Sbjct 1252 EEVKRLEGELERLEEELLTAQEARAAAEKNLDKANLELEELRQEADDAARDNDKLVKDNR 1311
Query 50 IITAKQEEIDTLTEQLTQLQSQFKQLNTDATALADRYSR-LEKSCTDLKNRFQEILAERN 108
+ A ++D QL + Q DA + AD SR L +LK R + ++
Sbjct 1312 KLKA---DLDEARIQLEEEQ--------DAKSHADSSSRRLLAEIEELKKRVAKETSD-- 1358
Query 109 ELRVTKEKLQAQQRQTHQEVQELQQDRDRLQKKNELAKSKVEAIIQRLSILGTSQDQHAQ 168
K+K Q Q+ +E + L+ DRD ++++N A+ +V + +L + D +
Sbjct 1359 -----KQKAQDQKANYQRENESLKADRDSIERRNRDAERQVRDLRAQLDDALSRLDSEKR 1413
Query 169 EIQQLADPTEEIQ 181
++ + E++
Sbjct 1414 AKEKSVEANRELK 1426
Score = 36.2 bits (82), Expect = 9e-06
Identities = 30/105 (29%), Positives = 48/105 (46%), Gaps = 10/105 (10%)
Query 55 QEEIDTLTEQLTQLQSQFKQLNTDATALADRYS--------RLEKSCTDLKNRFQEILAE 106
Q+EID L +Q+ L+ + L DA A D+ +LEK LK + ++ E
Sbjct 855 QKEIDDLKKQVKDLEKELAALK-DANAKLDKEKQLAEEDADKLEKDLAALKLKILDLEGE 913
Query 107 RNELRVTKEKLQAQQRQTHQEVQ-ELQQDRDRLQKKNELAKSKVE 150
+ +L LQ + +E+Q E D L++K +L K E
Sbjct 914 KADLEEDNALLQKKVAGLEEELQEETSASNDILEQKRKLEAEKGE 958
Score = 36.2 bits (82), Expect = 9e-06
Identities = 26/144 (18%), Positives = 66/144 (46%), Gaps = 3/144 (2%)
Query 3 EQLQRLQAHVGVLKTRLLHLESDNETLTQAKDE---SAAQHHSQIVQKNGIITAKQEEID 59
+Q++ L+ + LK L+ + + + D+ A +I+ G +E+
Sbjct 863 KQVKDLEKELAALKDANAKLDKEKQLAEEDADKLEKDLAALKLKILDLEGEKADLEEDNA 922
Query 60 TLTEQLTQLQSQFKQLNTDATALADRYSRLEKSCTDLKNRFQEILAERNELRVTKEKLQA 119
L +++ L+ + ++ + + + ++ +LE +LK +E R L+ K K+++
Sbjct 923 LLQKKVAGLEEELQEETSASNDILEQKRKLEAEKGELKASLEEEERNRKALQEAKTKVES 982
Query 120 QQRQTHQEVQELQQDRDRLQKKNE 143
++ + + ++ D L+KK E
Sbjct 983 ERNELQDKYEDEAAAHDSLKKKEE 1006
Score = 36.2 bits (82), Expect = 9e-06
Identities = 33/173 (19%), Positives = 74/173 (43%), Gaps = 15/173 (9%)
Query 3 EQLQRLQAHVGVLKTRLLHLESDNETLTQAKDESAAQHHSQIVQKNGIITAKQEEIDTLT 62
E +L+ + LK ++L LE + L + + ++QK + +EE+ T
Sbjct 891 EDADKLEKDLAALKLKILDLEGEKADL---------EEDNALLQKK--VAGLEEELQEET 939
Query 63 EQLTQLQSQFKQLNTDATALADRYSRLEKSCTDLKNRFQEILAERNELRVTKEKLQAQQR 122
+ Q ++L + L E++ L+ ++ +ERNEL+ E +
Sbjct 940 SASNDILEQKRKLEAEKGELKASLEEEERNRKALQEAKTKVESERNELQDKYE----DEA 995
Query 123 QTHQEVQELQQDRDRLQKKNELAKSKVEAIIQRLSILGTSQDQHAQEIQQLAD 175
H +++ ++D R ++ + A + E I + L + ++ A +++ D
Sbjct 996 AAHDSLKKKEEDLSRELRETKDALADAENISETLRSKLKNTERGADDVRNELD 1048
Score = 35.0 bits (79), Expect = 2e-05
Identities = 31/157 (20%), Positives = 65/157 (41%), Gaps = 2/157 (1%)
Query 20 LHLESDNETLTQAKDESAAQHHSQIVQKNGIITAKQEEIDTLTEQLTQLQSQFKQLNTDA 79
+ LE + + + A D S+ + ++I + + + + +Q Q + + L D
Sbjct 1322 IQLEEEQDAKSHA-DSSSRRLLAEIEELKKRVAKETSDKQKAQDQKANYQRENESLKADR 1380
Query 80 TALADRYSRLEKSCTDLKNRFQEILAERNELRVTKEKLQAQQRQTHQEVQELQ-QDRDRL 138
++ R E+ DL+ + + L+ + + KEK R+ + V + + Q + L
Sbjct 1381 DSIERRNRDAERQVRDLRAQLDDALSRLDSEKRAKEKSVEANRELKKVVLDRERQSLESL 1440
Query 139 QKKNELAKSKVEAIIQRLSILGTSQDQHAQEIQQLAD 175
K N +S + + + L Q +I QL D
Sbjct 1441 SKFNSALESDKQILEDEIGDLHEKNKQLQAKIAQLQD 1477
Score = 34.3 bits (77), Expect = 4e-05
Identities = 31/152 (20%), Positives = 59/152 (39%), Gaps = 1/152 (1%)
Query 4 QLQRLQAHVGVLKTRLLHLESDNETLTQAKDESAAQHHSQIVQKNGIITAKQEEIDTLTE 63
Q + L+ V K RL E+ L + + + + + + ++ L
Sbjct 1172 QAKTLKTQVDETKRRLEEAEASAARLEKERKNALDEVAQLTADLDAERDSGAQQRRKLNT 1231
Query 64 QLTQLQSQFKQLNTDATALADRYSRLEKSCTDLKNRFQEILAERNELRVTKEKLQAQQRQ 123
++++LQS+ + A ++ RLE L+ R +K + +
Sbjct 1232 RISELQSELENAPKTGGASSEEVKRLEGELERLEEELLTAQEARAAAEKNLDKANLELEE 1291
Query 124 THQEVQELQQDRDRLQKKNELAKSKV-EAIIQ 154
QE + +D D+L K N K+ + EA IQ
Sbjct 1292 LRQEADDAARDNDKLVKDNRKLKADLDEARIQ 1323
Score = 28.9 bits (63), Expect = 0.002
Identities = 29/151 (19%), Positives = 59/151 (39%), Gaps = 5/151 (3%)
Query 2 LEQLQRLQAHVGVLKTRLLH--LESDNETLTQAKDESAAQHHSQIVQK-NGIITAKQEEI 58
LE+ Q ++H RLL E + D+ AQ Q+ N + A ++ I
Sbjct 1324 LEEEQDAKSHADSSSRRLLAEIEELKKRVAKETSDKQKAQDQKANYQRENESLKADRDSI 1383
Query 59 DTLTEQLTQLQSQFKQLNTDATALADRYSRLEKSCTDLKNRFQEILAERNELRVTKEKLQ 118
+ + + DA + D R ++ + ++++ +R R + E L
Sbjct 1384 ERRNRDAERQVRDLRAQLDDALSRLDSEKRAKEKSVEANRELKKVVLDRE--RQSLESLS 1441
Query 119 AQQRQTHQEVQELQQDRDRLQKKNELAKSKV 149
+ Q L+ + L +KN+ ++K+
Sbjct 1442 KFNSALESDKQILEDEIGDLHEKNKQLQAKI 1472
Score = 27.7 bits (60), Expect = 0.005
Identities = 28/152 (18%), Positives = 70/152 (46%), Gaps = 18/152 (12%)
Query 32 AKDESAAQHHSQIVQKNGIITAKQEEIDTL-------TEQLTQLQSQFKQLNTDATALAD 84
A+ +S AQ ++ N I+ Q E++ +E++ +L+ + ++L + +
Sbjct 1217 AERDSGAQQRRKL---NTRISELQSELENAPKTGGASSEEVKRLEGELERLEEELLTAQE 1273
Query 85 RYSRLEKSCTDLKNRFQEILAERNELRVTKEKLQAQQRQTHQEVQE----LQQDRDRLQK 140
+ EK+ +E+ E ++ +KL R+ ++ E L++++D
Sbjct 1274 ARAAAEKNLDKANLELEELRQEADDAARDNDKLVKDNRKLKADLDEARIQLEEEQDAKSH 1333
Query 141 KNELAK---SKVEAIIQRLSILGTSQDQHAQE 169
+ ++ +++E + +R++ TS Q AQ+
Sbjct 1334 ADSSSRRLLAEIEELKKRVA-KETSDKQKAQD 1364
Score = 25.0 bits (53), Expect = 0.039
Identities = 15/68 (22%), Positives = 32/68 (47%), Gaps = 0/68 (0%)
Query 89 LEKSCTDLKNRFQEILAERNELRVTKEKLQAQQRQTHQEVQELQQDRDRLQKKNELAKSK 148
LEK LK+ ++ E+ +KL+ ++ +L+ ++ L++ N L + K
Sbjct 868 LEKELAALKDANAKLDKEKQLAEEDADKLEKDLAALKLKILDLEGEKADLEEDNALLQKK 927
Query 149 VEAIIQRL 156
V + + L
Sbjct 928 VAGLEEEL 935
Score = 20.8 bits (42), Expect = 0.89
Identities = 13/44 (30%), Positives = 24/44 (55%), Gaps = 3/44 (7%)
Query 35 ESAAQHHSQIVQKNGIITAKQEEIDTLTEQLTQLQSQFKQLNTD 78
ES ++ +S + I+ ++EI L E+ QLQ++ QL +
Sbjct 1438 ESLSKFNSALESDKQIL---EDEIGDLHEKNKQLQAKIAQLQDE 1478
>Q66H89 Centrosomal protein of 83 kDa [Rattus norvegicus]
Length=692
Score = 38.9 bits (89), Expect = 1e-06
Identities = 42/177 (24%), Positives = 81/177 (46%), Gaps = 21/177 (12%)
Query 2 LEQLQRLQAH-VGVLKTRLLHLESDNETLTQAKDESAAQHHSQIVQKNGIITAKQE---E 57
+E +QR+Q + ++ L LE++ ++ + + S Q +I+ + E
Sbjct 236 VENVQRIQVRQLAEMQATLRSLEAEKQSAKLQAERLEKELQSSNEQNTCLISKLHKADRE 295
Query 58 IDTLTEQLTQLQSQFKQLNTDATALADR-YSRLEKSCTDLKNRFQEILAERNELRVTKE- 115
I TLT Q+ +L+ K TD A R S LE+ +++ + ++ L+ T E
Sbjct 296 ISTLTSQVKELKHANKLEITDVKLEAARAKSELERERNKIQSELDGLQSDNEILKSTVEH 355
Query 116 --------------KLQAQQRQTHQEVQELQQDRDRLQKK-NELAKSKVEAIIQRLS 157
K+QA + + +Q++ LQ ++ L+ + ++L K KVE + R S
Sbjct 356 HKVLLVEKDRELIRKVQAAKEEGYQKLVVLQDEKLELENRLSDLEKMKVEHDVWRQS 412
Score = 38.9 bits (89), Expect = 1e-06
Identities = 44/181 (24%), Positives = 79/181 (44%), Gaps = 31/181 (17%)
Query 15 LKTRLLHLESDNETLTQAKDESAAQHHSQIVQKNGIITAKQEEIDTLTEQLTQLQSQFKQ 74
+++ L L+SDNE L +S +HH ++ ++ E + ++Q+ ++
Sbjct 335 IQSELDGLQSDNEIL-----KSTVEHHKVLL------------VEKDRELIRKVQAAKEE 377
Query 75 LNTDATALADRYSRLEKSCTDL-KNRFQEILAERNELRVTKEKLQAQQRQTHQEVQELQQ 133
L D LE +DL K + + + ++E +EKL+A Q +ELQ
Sbjct 378 GYQKLVVLQDEKLELENRLSDLEKMKVEHDVWRQSEKDQCEEKLRASQAAEEAARRELQS 437
Query 134 DRDRLQ---------KKNELAKSKVEAIIQRLSILGTSQDQHAQEI----QQLADPTEEI 180
R +LQ +K +L S+++ I L I TS Q ++ Q L D E +
Sbjct 438 IRLKLQQQIVNTEKAEKEKLENSELKQQISHLQIQVTSLTQSENDLLNSNQMLKDMVERL 497
Query 181 Q 181
+
Sbjct 498 K 498
Score = 35.8 bits (81), Expect = 1e-05
Identities = 38/176 (22%), Positives = 73/176 (41%), Gaps = 38/176 (22%)
Query 3 EQLQRLQAHVGVLKTRLLHLESD----NETLTQAKDESAAQHHSQIVQKNGIITAKQEEI 58
E+++R +A L+ L+S+ E LT+ +E ++ S++ +
Sbjct 130 EEVERYRAEYNKLRYEHTFLKSEFEHQKEELTRISEEEKMKYKSEVAR------------ 177
Query 59 DTLTEQLTQLQSQFKQLNTDATALADRYSRLEKSCTDLKNRFQEILAERNELRVTKE--- 115
L + +L +Q L+ D T + R +L + T L + + + AE ELR KE
Sbjct 178 --LEKDKEELHNQL--LSVDPTRDSKRVEQLVREKTHLLQKLKSLEAEVAELRAEKENSG 233
Query 116 ---------------KLQAQQRQTHQEVQELQQDRDRLQKKNELAKSKVEAIIQRL 156
++QA R E Q + +RL+K+ + + + +I +L
Sbjct 234 AQVENVQRIQVRQLAEMQATLRSLEAEKQSAKLQAERLEKELQSSNEQNTCLISKL 289
Score = 35.0 bits (79), Expect = 2e-05
Identities = 40/182 (22%), Positives = 84/182 (46%), Gaps = 20/182 (11%)
Query 3 EQLQRLQAHVGVLKTRLLHLESDNETLTQAKDESAAQHHSQIVQKNGIITAKQEEIDTLT 62
E+ ++ + LK ++ HL+ +LTQ++++ ++ N ++ ++ ++ L
Sbjct 450 EKAEKEKLENSELKQQISHLQIQVTSLTQSEND--------LLNSNQML---KDMVERLK 498
Query 63 EQLTQLQSQFK--QLNTDATALADRYSRLEKSCTDLKNRFQEILAERNE-LRVTKEKLQA 119
++ L+SQ + QL + T + LE+ K++ E + +R E KEKLQ
Sbjct 499 QECRHLRSQAEKVQLEVEKTLEEKQIQWLEE-----KHKLHERITDREEKYNQAKEKLQR 553
Query 120 QQRQTHQEVQELQQDRDRLQKKNELAKSKVEAIIQRLSILGTSQDQHAQEIQQLADPTEE 179
+ + RLQ+K E+ ++K E + +L Q+ +E +L ++
Sbjct 554 AATAQKKRKSLHENKLKRLQEKVEVLEAKKEELETENQVL-NRQNVPFEEYTRLQKRLKD 612
Query 180 IQ 181
IQ
Sbjct 613 IQ 614
Score = 31.6 bits (70), Expect = 3e-04
Identities = 43/206 (21%), Positives = 83/206 (40%), Gaps = 36/206 (17%)
Query 1 MLEQLQRLQAHVGVLKTRLLHLESDNETLTQAKDESAAQHHSQIVQKNGIITAKQEEIDT 60
+L Q L+ V LK HL S E + +++ + Q + EE
Sbjct 483 LLNSNQMLKDMVERLKQECRHLRSQAEKVQLEVEKTLEEKQIQWL----------EEKHK 532
Query 61 LTEQLTQLQSQFKQ----LNTDATALADRYSRLEKSCTDLKNRFQEILAERNELRVTKEK 116
L E++T + ++ Q L ATA R S E L+ + + + A++ EL T+ +
Sbjct 533 LHERITDREEKYNQAKEKLQRAATAQKKRKSLHENKLKRLQEKVEVLEAKKEELE-TENQ 591
Query 117 LQAQQRQTHQEVQELQQDRDRLQKKNELAKSKV------------------EAIIQRLSI 158
+ +Q +E LQ+ +Q+++ +S + AI+ + +
Sbjct 592 VLNRQNVPFEEYTRLQKRLKDIQRRHNEFRSLILVPNMPPAASVNPANFQSSAIVPGVEL 651
Query 159 L---GTSQDQHAQEIQQLADPTEEIQ 181
++QH +E+ L EE++
Sbjct 652 SFPPHLQEEQHQRELSLLRKRLEELE 677
Score = 27.7 bits (60), Expect = 0.005
Identities = 31/159 (19%), Positives = 75/159 (47%), Gaps = 17/159 (11%)
Query 21 HLESDNETLTQAKDESAAQHHSQIV--QKNGIITAKQEEIDTLTEQLT---QLQSQFKQL 75
+++S NE ++ Q Q++ + G + K ++++ + Q+ +L+ QL
Sbjct 54 YVKSQNELKRVLNEKQTNQEKFQLLLEELRGELVEKVKDMEAMKLQILTPQKLELVKAQL 113
Query 76 NTDATA-LADRYSRLEKSCTDLKNRFQEILAERNELRVTKEKLQAQQRQTHQEVQELQQD 134
+ A + +R+ L++ + AE N+LR L+++ +E+ + ++
Sbjct 114 QQELEAPMRERFRTLDEEV-------ERYRAEYNKLRYEHTFLKSEFEHQKEELTRISEE 166
Query 135 RDRLQKKNELA---KSKVEAIIQRLSILGTSQDQHAQEI 170
++++ K+E+A K K E Q LS+ T + +++
Sbjct 167 -EKMKYKSEVARLEKDKEELHNQLLSVDPTRDSKRVEQL 204
Score = 26.2 bits (56), Expect = 0.016
Identities = 25/139 (18%), Positives = 69/139 (50%), Gaps = 9/139 (6%)
Query 39 QHHSQIVQKNGIITAKQEEIDTLTEQLTQLQSQFKQLNTDATALADRYSRL-EKSCTDLK 97
+HH Q A + E L E+ + Q++ K++ + +++ L E+ +L
Sbjct 34 EHHKHNYQ------ALKIEHKRLQEEYVKSQNELKRVLNEKQTNQEKFQLLLEELRGELV 87
Query 98 NRFQEILAERNELRVTKEKLQAQQRQTHQEVQELQQDRDR-LQKKNELAKSKVEAIIQRL 156
+ +++ A + ++ +T +KL+ + Q QE++ ++R R L ++ E +++ +
Sbjct 88 EKVKDMEAMKLQI-LTPQKLELVKAQLQQELEAPMRERFRTLDEEVERYRAEYNKLRYEH 146
Query 157 SILGTSQDQHAQEIQQLAD 175
+ L + + +E+ ++++
Sbjct 147 TFLKSEFEHQKEELTRISE 165
Score = 20.4 bits (41), Expect = 1.1
Identities = 13/71 (18%), Positives = 35/71 (49%), Gaps = 5/71 (7%)
Query 110 LRVTKEKLQAQQRQTHQEVQELQQDRDRLQKKNELAKSKVEAIIQRLSILGTSQDQHAQE 169
L++ ++LQ + ++ E++ + ++ Q+K +L ++ R ++ +D A +
Sbjct 43 LKIEHKRLQEEYVKSQNELKRVLNEKQTNQEKFQLLLEEL-----RGELVEKVKDMEAMK 97
Query 170 IQQLADPTEEI 180
+Q L E+
Sbjct 98 LQILTPQKLEL 108
Score = 20.4 bits (41), Expect = 1.1
Identities = 18/80 (23%), Positives = 39/80 (49%), Gaps = 9/80 (11%)
Query 101 QEILAERNELRVTKEKLQAQQRQTHQEVQELQQDRDRLQKKNELAKSKVEAII-QRLSIL 159
+E + +NEL+ + Q Q + ++EL+ + ++K ++ K++ + Q+L ++
Sbjct 52 EEYVKSQNELKRVLNEKQTNQEKFQLLLEELR--GELVEKVKDMEAMKLQILTPQKLELV 109
Query 160 GTSQDQHAQEIQQLADPTEE 179
AQ Q+L P E
Sbjct 110 ------KAQLQQELEAPMRE 123
Lambda K H a alpha
0.314 0.126 0.325 0.792 4.96
Gapped
Lambda K H a alpha sigma
0.267 0.0410 0.140 1.90 42.6 43.6
Effective search space used: 1639088
Database: 7d62acd3c072339bb54b8b620a602d43.SwissProt.fasta
Posted date: May 8, 2024 3:15 PM
Number of letters in database: 12,771
Number of sequences in database: 11
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Neighboring words threshold: 11
Window for multiple hits: 40
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Data ...
