BLASTP 2.12.0+
Reference: Stephen F. Altschul, Thomas L. Madden, Alejandro A.
Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J.
Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of
protein database search programs", Nucleic Acids Res. 25:3389-3402.
Reference for composition-based statistics: Alejandro A. Schaffer,
L. Aravind, Thomas L. Madden, Sergei Shavirin, John L. Spouge, Yuri
I. Wolf, Eugene V. Koonin, and Stephen F. Altschul (2001),
"Improving the accuracy of PSI-BLAST protein database searches with
composition-based statistics and other refinements", Nucleic Acids
Res. 29:2994-3005.
Database: 9779d6877d2fe68a4582dbd9d4ff6267.SwissProt.fasta
14 sequences; 6,219 total letters
Query= ACIAD1128
Length=411
Score E
Sequences producing significant alignments: (Bits) Value
P25535 2-octaprenylphenol hydroxylase [Escherichia coli (strain K... 195 1e-61
P75728 3-demethoxyubiquinol 3-hydroxylase [Escherichia coli (stra... 195 1e-61
Q2RMZ4 Ubiquinone hydroxylase UbiL [Rhodospirillum rubrum (strain... 176 7e-54
Q9VMQ5 Ubiquinone biosynthesis monooxygenase COQ6, mitochondrial ... 168 1e-50
P72835 Uncharacterized protein slr1300 [Synechocystis sp. (strain... 146 4e-43
F1RAX8 Ubiquinone biosynthesis monooxygenase COQ6, mitochondrial ... 147 1e-42
Q8R1S0 Ubiquinone biosynthesis monooxygenase COQ6, mitochondrial ... 144 1e-41
Q68FU7 Ubiquinone biosynthesis monooxygenase COQ6, mitochondrial ... 144 1e-41
Q2KIL4 Ubiquinone biosynthesis monooxygenase COQ6, mitochondrial ... 140 3e-40
Q9Y2Z9 Ubiquinone biosynthesis monooxygenase COQ6, mitochondrial ... 139 5e-40
A1KVW0 Ubiquinone hydroxylase UbiM [Neisseria meningitidis serogr... 120 4e-33
P25534 2-octaprenyl-6-methoxyphenol hydroxylase [Escherichia coli... 119 4e-33
P53318 Ubiquinone biosynthesis monooxygenase COQ6, mitochondrial ... 101 1e-26
C1I201 Para-nitrophenol 4-monooxygenase [Pseudomonas sp. (strain ... 73.2 2e-17
>P25535 2-octaprenylphenol hydroxylase [Escherichia coli (strain
K12)]
Length=400
Score = 195 bits (496), Expect = 1e-61
Identities = 147/406 (36%), Positives = 205/406 (50%), Gaps = 17/406 (4%)
Query 3 QIADVVIVGGGLVGGLTALLLAQGGVQATVLDAAPILDTAKVESVMNPRVLALSQATIHL 62
Q DV IVGGG+VG A L G++ VL+ + + + RV A++ A+ L
Sbjct 2 QSVDVAIVGGGMVGLAVACGLQGSGLRVAVLEQR-VQEPLAANAPPQLRVSAINAASEKL 60
Query 63 LKTVEVWE--LISRQMPYTGMQVWNKNGYGDIQFGHHSASTPMIDQALGSMVEPSLLNLA 120
L + VW+ L R Y GM+VW+K+ +G I F S M LG +VE S+++ A
Sbjct 61 LTRLGVWQDILSRRASCYHGMEVWDKDSFGHISFDDQS----MGYSHLGHIVENSVIHYA 116
Query 121 IQQKMRAVIQ-DYRTEVQVVQIEQLPNLWQIHLADGHCIQTRLLIGADGANSFVREKAMI 179
+ K ++ Q+ N + L DG + RL+IGADGANS++R KA I
Sbjct 117 LWNKAHQSSDITLLAPAELQQVAWGENETFLTLKDGSMLTARLVIGADGANSWLRNKADI 176
Query 180 DLDVLDYKQAAISCAIKTALSHEHVARQIFLPTGPLAFLPMASLVPAEQGLWQSIVWTLP 239
L DY+ A+ I+T H+ VARQ+F G LAFLP++ SIVW+L
Sbjct 177 PLTFWDYQHHALVATIRTEEPHDAVARQVFHGEGILAFLPLSDPHLC------SIVWSLS 230
Query 240 DDYADEYSALSDHEFKALLTRESQHMLGEVVEVRSRAQFPLKARAAKQYVKEGLALIGDA 299
+ A S+ EF L + LG +R FPL R A+Q+ LAL+GDA
Sbjct 231 PEEAQRMQQASEDEFNRALNIAFDNRLGLCKVESARQVFPLTGRYARQFASHRLALVGDA 290
Query 300 AHVIHPLAGQGVNIGCLDAAVLCDAL--LHDRARGVWAHEQTLRRYEHERKGQNDAMMHG 357
AH IHPLAGQGVN+G +DAA L L LH + + + + LRRYE RK M+ G
Sbjct 291 AHTIHPLAGQGVNLGFMDAAELIAELKRLHRQGKDIGQYIY-LRRYERSRKHSAALMLAG 349
Query 358 MSIIGWLESQEFFPLIALRNTGLRWVENSEILKNSFLQQATGLSIL 403
M L S LR+ GL+ + +K ++QA GL+ L
Sbjct 350 MQGFRDLFSGTNPAKKLLRDIGLKLADTLPGVKPQLIRQAMGLNDL 395
>P75728 3-demethoxyubiquinol 3-hydroxylase [Escherichia coli (strain
K12)]
Length=391
Score = 195 bits (495), Expect = 1e-61
Identities = 139/402 (35%), Positives = 203/402 (50%), Gaps = 18/402 (4%)
Query 3 QIADVVIVGGGLVGGLTALLLAQGGVQATVLDAAPILDTAKVESVMNPRVLALSQATIHL 62
Q ++ IVGGG+VGG AL LAQ G TV++ A +S + R+ A+S A++ L
Sbjct 4 QPTEIAIVGGGMVGGALALGLAQHGFAVTVIEHAEPAPFV-ADSQPDVRISAISAASVSL 62
Query 63 LKTVEVWELIS--RQMPYTGMQVWNKNGYGDIQFGHHSASTPMIDQALGSMVEPSLLNLA 120
LK + VW+ + R PY ++ W + F P+ LG MVE ++L A
Sbjct 63 LKGLGVWDAVQAMRCHPYRRLETWEWET-AHVVFDAAELKLPL----LGYMVENTVLQQA 117
Query 121 IQQKMRAVIQ-DYRTEVQVVQIEQLPNLWQIHLADGHCIQTRLLIGADGANSFVREKAMI 179
+ Q + A + R ++ + + +L ++ L G I+ +L+IGADGANS VR+ A I
Sbjct 118 LWQALEAHPKVTLRVPGSLIALHRHDDLQELELKGGEVIRAKLVIGADGANSQVRQMAGI 177
Query 180 DLDVLDYKQAAISCAIKTALSHEHVARQIFLPTGPLAFLPMASLVPAEQGLWQSIVWTLP 239
+ Y Q+ + +++ Q F P GP AFLP+ W S+VW
Sbjct 178 GVHAWQYAQSCMLISVQCENDPGDSTWQQFTPDGPRAFLPLFDN-------WASLVWYDS 230
Query 240 DDYADEYSALSDHEFKALLTRESQHMLGEVVEVRSRAQFPLKARAAKQYVKEGLALIGDA 299
+ ++ + +A + + LG V + + A FPL R A QYV+ GLAL+GDA
Sbjct 231 PARIRQLQNMNMAQLQAEIAKHFPSRLGYVTPLAAGA-FPLTRRHALQYVQPGLALVGDA 289
Query 300 AHVIHPLAGQGVNIGCLDAAVLCDALLHDRARG-VWAHEQTLRRYEHERKGQNDAMMHGM 358
AH IHPLAGQGVN+G D L D L++ R+ G WA L+RY+ R N M GM
Sbjct 290 AHTIHPLAGQGVNLGYRDVDALIDVLVNARSYGEAWASYPVLKRYQMRRMADNFIMQSGM 349
Query 359 SIIGWLESQEFFPLIALRNTGLRWVENSEILKNSFLQQATGL 400
+ S PL +RN GL E + +LK L+ A GL
Sbjct 350 DLFYAGFSNNLPPLRFMRNLGLMAAERAGVLKRQALKYALGL 391
>Q2RMZ4 Ubiquinone hydroxylase UbiL [Rhodospirillum rubrum (strain
ATCC 11170 / ATH 1.1.1 / DSM 467 / LMG 4362 / NCIMB 8255
/ S1)]
Length=429
Score = 176 bits (445), Expect = 7e-54
Identities = 136/400 (34%), Positives = 193/400 (48%), Gaps = 17/400 (4%)
Query 3 QIADVVIVGGGLVGGLTALLLAQGGVQATVLDAAPILDTAKVESVMNPRVLALSQATIHL 62
++ADV+IVGGGLVGG A LA+ GV V+D A + + + R A++ A L
Sbjct 27 KVADVLIVGGGLVGGTLACALAEKGVSVVVIDGED--PEALLAAGYDGRCSAIALACQRL 84
Query 63 LKTVEVWELISRQ-MPYTGMQVWNKNGYGDIQFGHHSASTPMIDQALGSMVEPSLLNLAI 121
L T+ +W+L+ + P ++V + + + A PM G MVE LL AI
Sbjct 85 LDTIGLWDLLGGESQPILDIRVVDGGSPLFLHYAQAEAQGPM-----GYMVENRLLRQAI 139
Query 122 QQKM-RAVIQDYRTEVQVVQIEQLPNLWQIHLADGHCIQTRLLIGADGANSFVREKAMID 180
++ R ++ + + + L+DG ++ RL++GADG S VRE A I
Sbjct 140 LTRLGRLPAATLLAPARMTALRRDLDGVSATLSDGQTVRARLVVGADGRRSQVRESAGIG 199
Query 181 LDVLDYKQAAISCAIKTALSHEHVARQIFLPTGPLAFLPMASLVPAEQGLWQSIVWTLPD 240
+ L Y Q AI ++ SH A + FLP GP A LPM G S+VWT
Sbjct 200 IRTLGYGQTAIVLTVEHERSHRGCAVEHFLPAGPFAILPMP-------GNRSSLVWTERS 252
Query 241 DYADEYSALSDHEFKALLTRESQHMLGEVVEVRSRAQFPLKARAAKQYVKEGLALIGDAA 300
D AL F+A L R LG V V R + L +AA +YV LAL+GDAA
Sbjct 253 DLVPGLLALPAEHFQAELERRFGDHLGWVRPVGPRFSYRLTLQAANRYVDHRLALVGDAA 312
Query 301 HVIHPLAGQGVNIGCLDAAVLCDALLHDRARGV-WAHEQTLRRYEHERKGQNDAMMHGMS 359
H +HP+AGQG+N G D AVL + L+ + G+ L YE R+ N M+
Sbjct 313 HGMHPVAGQGMNYGLRDVAVLAERLVAAQRLGLDPGAPALLAEYEALRRPDNLLMLAITD 372
Query 360 IIGWLESQEFFPLIALRNTGLRWVENSEILKNSFLQQATG 399
+ L S + P+ R G+ VE LK F++ A G
Sbjct 373 ALVRLFSNDIAPVALARRLGIGAVERMGPLKRLFMRHAMG 412
>Q9VMQ5 Ubiquinone biosynthesis monooxygenase COQ6, mitochondrial
[Drosophila melanogaster]
Length=477
Score = 168 bits (425), Expect = 1e-50
Identities = 134/442 (30%), Positives = 205/442 (46%), Gaps = 55/442 (12%)
Query 2 TQIADVVIVGGGLVGGLTALLLAQGGVQAT----VLDAAPILDTAKVESVMNPRVLALSQ 57
T+ D++I GGGLVG A LA+ A +L+ AP RV A++
Sbjct 46 TEHFDIIIGGGGLVGTTLAAALAKNSTLADKKVLLLEGAPEFRGFNPTGPYQNRVSAINH 105
Query 58 ATIHLLKTVEVWELI--SRQMPYTGMQVWNKNGYGDIQFGHHSASTPMIDQALGSMVEPS 115
+I L K+++ W+ I +R P MQVW N IQF H + ++ + ++ +
Sbjct 106 NSIELFKSIDAWKHIESARYKPVKQMQVWESNTDALIQFQHDNFASDVACIIENDLILDA 165
Query 116 LLNLAIQQKMRAVIQDYRTEVQVVQIEQLPNLWQIHLADGHCIQTRLLIGADGANSFVRE 175
+ LA + ++ R + + + N ++ L DG LLIGADGANS VR+
Sbjct 166 VYALAKESPNVEILNKARIQCVRLPRDSNSNHSELQLEDGRNFSCDLLIGADGANSVVRK 225
Query 176 KAMIDLDVLDYKQAAISCAIKTA--LSHEHVARQIFLPTGPLAFLPMASLVPAEQGLWQS 233
+ +D+ L+Y + + ++ VA Q FLP GP+A LP+ + S
Sbjct 226 EMNVDVFSLNYDRMGLVATLELGEDACDNSVAWQRFLPNGPVALLPLTDRL-------SS 278
Query 234 IVWTLPDDYADEYSALSDHEFKALLTRE--------------------------SQHMLG 267
+VW+ ++ A AL EF L SQH +
Sbjct 279 LVWSTTNEQAKMLQALPPTEFVDALNEAFCRQYPRVELADKAVQALNSLFGHNGSQHQVQ 338
Query 268 EVVEV-----RSRAQFPLKARAAKQYVKEGLALIGDAAHVIHPLAGQGVNIGCLDAAVLC 322
V +SRA FPL A YV G AL+GDAAH +HPLAGQGVN+G D L
Sbjct 339 YPPRVCGVLDKSRATFPLGFLHASSYVCNGAALVGDAAHRVHPLAGQGVNLGFSDVRYLV 398
Query 323 DALLHDRARGVWA-----HEQTLRRYEHERKGQNDAMMHGMSIIGWLESQEFFPLIALRN 377
++L A G +A +Q L +YE + +N +M G+ + L + +F P++ LR+
Sbjct 399 ESL----AAGAYAGFKLGDKQHLIKYERKCLAKNVPIMLGVHGLHTLYATQFSPVVLLRS 454
Query 378 TGLRWVENSEILKNSFLQQATG 399
GL+ +N +KN F++ A G
Sbjct 455 LGLQLTQNLPPVKNLFMRGAMG 476
>P72835 Uncharacterized protein slr1300 [Synechocystis sp. (strain
PCC 6803 / Kazusa)]
Length=414
Score = 146 bits (369), Expect = 4e-43
Identities = 116/401 (29%), Positives = 191/401 (48%), Gaps = 22/401 (5%)
Query 6 DVVIVGGGLVGGLTALLLAQGGVQATVLDAAPILDTAKVESVMNPRVLALSQATIHLLKT 65
DV I GGG+VG + A L G++ +++A P K +++ P+ A+S + +L
Sbjct 14 DVAIAGGGVVGLVLAAGLRHTGLKIAIIEALP-----KEQALTKPQAYAISLLSGKILAG 68
Query 66 VEVWELISRQMP-YTGMQVWNKNGYGDIQFGHHSASTPMIDQALGSMVEPSLLNLAIQQK 124
+ VWE I + + +Q+ + + G + F A + + ALG + E ++ A++
Sbjct 69 LGVWENIKDSIGHFERIQISDNDYRGTVPF----AKEDVDELALGHVAEHPVILQALENC 124
Query 125 MRAVIQ-DYRTEVQVVQIEQLPNLWQIHLA-DGH--CIQTRLLIGADGANSFVREKAMID 180
+ + + +++ N Q+ L +G +QT+LL+ ADGA S R A I
Sbjct 125 VEQCPRIAWFRPAELISFTAGENHKQVTLQQEGREITLQTKLLVAADGARSHTRSLAGIQ 184
Query 181 LDVLDYKQAAISCAIKTALSHEHVARQIFLPTGPLAFLPMASLVPAEQGLWQSIVWTLPD 240
Y Q+ ++ I+ A + F TGP+ LP+ P ++ IVWT+P
Sbjct 185 TKGWKYWQSCVAFTIQHQAPDNTTAFERFCDTGPMGILPL----PGDRA---QIVWTMPH 237
Query 241 DYADEYSALSDHEFKALLTRESQHMLGEVVEVRSRAQFPLKARAAKQYVKEGLALIGDAA 300
A L + +F L + LGE + +R FP++ + YV+ LAL+GDAA
Sbjct 238 HKAHTLVNLPEADFITELRQRIGDRLGEFHLINARRLFPVQLMQSDCYVQPRLALVGDAA 297
Query 301 HVIHPLAGQGVNIGCLDAAVLCDALLHDRARGV-WAHEQTLRRYEHERKGQNDAMMHGMS 359
H HP+ GQG+N+G D A L + ++G W L+RYEH RK +N ++
Sbjct 298 HCCHPVGGQGLNLGIRDGAALAQVIATAHSQGEDWGSLAVLKRYEHWRKPENWLILGFTD 357
Query 360 IIGWLESQEFFPLIALRNTGLRWVENSEILKNSFLQQATGL 400
++ S + P IALR GL + K L+ TGL
Sbjct 358 LLDRFFSSHWLPAIALRRFGLEVLRLVPPAKKLALRLMTGL 398
>F1RAX8 Ubiquinone biosynthesis monooxygenase COQ6, mitochondrial
[Danio rerio]
Length=484
Score = 147 bits (370), Expect = 1e-42
Identities = 131/454 (29%), Positives = 206/454 (45%), Gaps = 77/454 (17%)
Query 3 QIADVVIVGGGLVGGLTALLLAQG------GVQATVLDAAPILDTAKVESVMNPRVLALS 56
++ D++I GGG+VG TA+ + G G + +L+A K+ + RV ++S
Sbjct 49 ELFDIIISGGGMVG--TAMACSLGLDPNLTGKKILLLEAGHEKKMDKIPETYSTRVSSIS 106
Query 57 QATIHLLKTVEVWELI--SRQMPYTGMQVWNKNGYGDIQFGHHSASTPMIDQALGSMVEP 114
+ LL + W+ I R PY MQVW+ I F + + + +VE
Sbjct 107 PGSATLLSGLGAWDHIVNMRCKPYNKMQVWDACSDALITFDKEN-----LQDEMAYIVEN 161
Query 115 SLLNLAIQQKMRAVIQ----DYRTEVQVVQ-------IEQLPNLW-QIHLADGHCIQTRL 162
++ A+ ++++ + YRT+V E +P W Q+ LA+G + T+L
Sbjct 162 DVIVAALTKQLQTLSDHVKVQYRTKVVKYTWPHPYHVSESIP--WVQVALANGKTLHTKL 219
Query 163 LIGADGANSFVREKAMIDLDVLDYKQAAISCAIKTALSHE-HVARQIFLPTGPLAFLPMA 221
LIGADG NS VR +A I +Y Q+A+ + + E +VA Q FLPTGP+A LP++
Sbjct 220 LIGADGPNSMVRREAGIPTVKWNYDQSAVVAVLHLSEPTENNVAWQRFLPTGPIAMLPLS 279
Query 222 SLVPAEQGLWQSIVWTLPDDYADEYSALSDHEF-----KALLTRESQHMLGEV------- 269
S+VW+ +A+E + + F A + E+ L E
Sbjct 280 DTE-------SSLVWSTSHQHAEELLQMDEESFVDAINSAFWSNENHSELVETAGSLFRM 332
Query 270 ---------------------VEVRSRAQFPLKARAAKQYVKEGLALIGDAAHVIHPLAG 308
+ +SR FPL A +Y++ +ALIGDAAH +HPLAG
Sbjct 333 ALSVLMPDSGSARQLPPSVSGIGPKSRVMFPLGMGHATEYIRHRVALIGDAAHRVHPLAG 392
Query 309 QGVNIGCLDAA----VLCDALLHDRARGVWAHEQTLRRYEHERKGQNDAMMHGMSIIGWL 364
QG N+G D + VL A + + G H L +E ER+ N MM + ++ L
Sbjct 393 QGANLGFGDVSYLTQVLSQAAYNGKDIGAMQH---LLEFETERQRHNLPMMTAIDLMKRL 449
Query 365 ESQEFFPLIALRNTGLRWVENSEILKNSFLQQAT 398
S P++ LR GL+ LK + A+
Sbjct 450 YSSNTAPMVLLRTFGLQATNAVPPLKEQIMAFAS 483
>Q8R1S0 Ubiquinone biosynthesis monooxygenase COQ6, mitochondrial
[Mus musculus]
Length=476
Score = 144 bits (362), Expect = 1e-41
Identities = 133/452 (29%), Positives = 203/452 (45%), Gaps = 76/452 (17%)
Query 4 IADVVIVGGGLVGGLTALLLAQG----GVQATVLDAAPILDTAKVESVMNPRVLALSQAT 59
+ DVV+ GGGLVG A L + +L+A P K+ + RV ++S +
Sbjct 43 VYDVVVSGGGLVGSAMACALGHDIHFHDKKILLLEAGPKKALEKLSETYSNRVSSISPGS 102
Query 60 IHLLKTVEVWELIS--RQMPYTGMQVWNKNGYGDIQFGHHSASTPMIDQALGSMVEPSLL 117
LL + W+ I R + MQVW+ I F + +G +VE ++
Sbjct 103 TTLLSSFGAWDHICNMRCKAFRRMQVWDSCSEALIMFDRDNLDD------MGYIVENDVI 156
Query 118 NLAIQQKMRAVIQDYRTEVQVVQIEQLPNLW-------------QIHLADGHCIQTRLLI 164
A+ +++ AV + + + + + W I L DG +QT+LLI
Sbjct 157 MYALTKQLEAVADRVKV---LYESKAVGYSWPGAFSMADSSPWVHITLGDGSTLQTKLLI 213
Query 165 GADGANSFVREKAMIDLDVLDYKQAAISCAIKTALSHEH-VARQIFLPTGPLAFLPMASL 223
GADG S VR+ A I Y Q+A+ + + + E+ VA Q FLP+GP+A LP++
Sbjct 214 GADGHKSGVRQAAGIQNVSWKYDQSAVVATLHLSEATENNVAWQRFLPSGPIALLPLSDT 273
Query 224 VPAEQGLWQSIVWTLPDDYADEYSALSDHEFK---------------------------- 255
+ S+VW+ ++A E ++ + EF
Sbjct 274 L-------SSLVWSTSHEHAAELVSMDEEEFVDAINSAFWSDVHHTDFVDSASAMVRHAV 326
Query 256 ALL--TRESQHMLGEV---VEVRSRAQFPLKARAAKQYVKEGLALIGDAAHVIHPLAGQG 310
ALL T+ S L V+ +SRA FPL A +YV+ +ALIGDAAH IHPLAGQG
Sbjct 327 ALLKPTKVSARQLPPSIAKVDAKSRALFPLGLGHAAEYVRPRVALIGDAAHRIHPLAGQG 386
Query 311 VNIGCLDAAV----LCDALLHDRARGVWAHEQTLRRYEHERKGQNDAMMHGMSIIGWLES 366
VN+G D + L A + + G +H L YE +R+ N A++ ++ L S
Sbjct 387 VNMGFGDISSLVHHLSTAAFNGKDLGSMSH---LTGYETDRQRHNTALLAATDLLKRLYS 443
Query 367 QEFFPLIALRNTGLRWVENSEILKNSFLQQAT 398
PL+ LR GL+ LK + A+
Sbjct 444 TSATPLVLLRTWGLQATNAVSPLKEQIMAFAS 475
>Q68FU7 Ubiquinone biosynthesis monooxygenase COQ6, mitochondrial
[Rattus norvegicus]
Length=476
Score = 144 bits (362), Expect = 1e-41
Identities = 131/448 (29%), Positives = 200/448 (45%), Gaps = 68/448 (15%)
Query 4 IADVVIVGGGLVGGLTALLLAQG----GVQATVLDAAPILDTAKVESVMNPRVLALSQAT 59
+ DVV+ GGG+VG A L + +L+A P K+ + RV ++S +
Sbjct 43 VYDVVVSGGGMVGSAMACALGHDIHFHDKKILLLEAGPKKTLEKLSETYSNRVSSISLGS 102
Query 60 IHLLKTVEVWELIS--RQMPYTGMQVWNKNGYGDIQFGHHSASTPMIDQALGSMVEPSLL 117
LL + W+ I R + MQVW+ I F + +G +VE ++
Sbjct 103 TTLLSSFGAWDHICNMRCKAFRRMQVWDSCSEALIMFDKDNLDD------MGYIVENDVI 156
Query 118 NLAIQQKMRAVIQDYRTEVQVVQIEQLPNLW-------------QIHLADGHCIQTRLLI 164
AI +++ AV + + + + + W I L DG +QT+LLI
Sbjct 157 MHAITKQLEAVADRVKV---LYESKAVGYAWPGPFSLADSSPWVHITLGDGSTLQTKLLI 213
Query 165 GADGANSFVREKAMIDLDVLDYKQAAISCAIKTALSHEH-VARQIFLPTGPLAFLPMASL 223
GADG NS VR+ A I +Y Q+A+ + + + E+ VA Q FLP+GP+A LP++
Sbjct 214 GADGHNSGVRQAAGIQNVGWNYDQSAVVATLHLSEATENNVAWQRFLPSGPIALLPLSDT 273
Query 224 VPA-------------------------EQGLWQSIVWTLPDDYADEYSALSDHEFKALL 258
+ + W + T D+ D SA+ H L
Sbjct 274 LSSLVWSTSHAHAAELVSMHEEEFVDAINSAFWSDVHHT---DFVDSASAMVHHAVALLK 330
Query 259 -TRESQHMLGEVV---EVRSRAQFPLKARAAKQYVKEGLALIGDAAHVIHPLAGQGVNIG 314
T+ S L V + +SRA FPL A +YV+ +ALIGDAAH +HPLAGQGVN+G
Sbjct 331 PTKVSARQLPPSVAKVDAKSRALFPLGLGHAAEYVRPRVALIGDAAHRVHPLAGQGVNMG 390
Query 315 CLDAA----VLCDALLHDRARGVWAHEQTLRRYEHERKGQNDAMMHGMSIIGWLESQEFF 370
D + L A + + G +H L YE +R+ N A++ ++ L S
Sbjct 391 FGDISSLIHYLSTAAFNGKDLGSMSH---LTGYETDRQRHNTALLAATDLLKRLYSTSTT 447
Query 371 PLIALRNTGLRWVENSEILKNSFLQQAT 398
PL+ LR GL+ LK + A+
Sbjct 448 PLVLLRTWGLQATNAVSPLKEQIMAFAS 475
>Q2KIL4 Ubiquinone biosynthesis monooxygenase COQ6, mitochondrial
[Bos taurus]
Length=469
Score = 140 bits (352), Expect = 3e-40
Identities = 132/447 (30%), Positives = 197/447 (44%), Gaps = 66/447 (15%)
Query 4 IADVVIVGGGLVGGLTALLLAQG----GVQATVLDAAPILDTAKVESVMNPRVLALSQAT 59
+ DVV+ GGGLVG A L + +L+A P K+ + RV ++S +
Sbjct 36 VYDVVVSGGGLVGAAMACALGHDIHFCDKKILLLEAGPKKVLEKLPETYSNRVSSISPGS 95
Query 60 IHLLKTVEVWELIS--RQMPYTGMQVWNKNGYGDIQFGHHS-------ASTPMIDQALGS 110
LL + W+ I R + MQVW+ I F + +I AL
Sbjct 96 ATLLSSFGAWDHICNMRCRAFRRMQVWDACSEALIMFDKDNLDDMGYIVENDVIMHALTK 155
Query 111 MVEPSLLNLAIQQKMRAVIQDYRTEVQVVQIEQLPNLW-QIHLADGHCIQTRLLIGADGA 169
+E + + K +AV Y + P W I L DG +QT+LLIGADG
Sbjct 156 QLEAVSDQVTVLYKSKAV--SYTWPYPFSMADSSP--WVHITLGDGRTLQTKLLIGADGH 211
Query 170 NSFVREKAMIDLDVLDYKQAAISCAIKTALSHEH-VARQIFLPTGPLAFLPMASLVPAEQ 228
NS VR+ A I +Y Q+A+ + + + E+ VA Q FLP+GP+A LP++ +
Sbjct 212 NSGVRQAAGIRNVSWNYDQSAVVATLHLSEATENNVAWQRFLPSGPIALLPLSDTL---- 267
Query 229 GLWQSIVWTLPDDYADEYSALSDHEFKALL------------------------------ 258
S+VW+ ++A E ++ + EF +
Sbjct 268 ---SSLVWSTSHEHAAELVSMEEEEFVDAINSAFWSDVNHTDFIDSAGSMLQSAVAFLKP 324
Query 259 TRESQHMLGEVV---EVRSRAQFPLKARAAKQYVKEGLALIGDAAHVIHPLAGQGVNIGC 315
TR S L V + +SR FPL A +YV+ LALIGDAAH +HPLAGQGVN+G
Sbjct 325 TRVSARQLPPSVARVDAKSRVLFPLGLGHAAEYVRPRLALIGDAAHRVHPLAGQGVNMGF 384
Query 316 LDAAV----LCDALLHDRARGVWAHEQTLRRYEHERKGQNDAMMHGMSIIGWLESQEFFP 371
D + L A + + G +H L YE +R+ N A++ ++ L S
Sbjct 385 GDISSLLHHLSTAAFNGKDLGSMSH---LTSYETDRQRHNTALLAATDLLKRLYSTRATL 441
Query 372 LIALRNTGLRWVENSEILKNSFLQQAT 398
++ LR GL+ LK + A+
Sbjct 442 VVLLRTWGLQATNAVSPLKEQIMAFAS 468
>Q9Y2Z9 Ubiquinone biosynthesis monooxygenase COQ6, mitochondrial
[Homo sapiens]
Length=468
Score = 139 bits (350), Expect = 5e-40
Identities = 134/451 (30%), Positives = 203/451 (45%), Gaps = 74/451 (16%)
Query 4 IADVVIVGGGLVGGLTALLLAQG----GVQATVLDAAPILDTAKVESVMNPRVLALSQAT 59
+ DVV+ GGGLVG A L + +L+A P K+ + RV ++S +
Sbjct 35 VYDVVVSGGGLVGAAMACALGYDIHFHDKKILLLEAGPKKVLEKLSETYSNRVSSISPGS 94
Query 60 IHLLKTVEVWELIS--RQMPYTGMQVWNKNGYGDIQFGHHSASTPMIDQALGSMVEPSLL 117
LL + W+ I R + MQVW+ I F + +G +VE ++
Sbjct 95 ATLLSSFGAWDHICNMRYRAFRRMQVWDACSEALIMFDKDNLDD------MGYIVENDVI 148
Query 118 NLAIQQKMRAVIQD----YRTEV-------QVVQIEQLPNLW-QIHLADGHCIQTRLLIG 165
A+ +++ AV YR++ + P W I L DG QT+LLIG
Sbjct 149 MHALTKQLEAVSDRVTVLYRSKAIRYTWPCPFPMADSSP--WVHITLGDGSTFQTKLLIG 206
Query 166 ADGANSFVREKAMIDLDVLDYKQAAISCAIKTALSHEH-VARQIFLPTGPLAFLPMASLV 224
ADG NS VR+ I +Y Q+A+ + + + E+ VA Q FLP+GP+A LP++ +
Sbjct 207 ADGHNSGVRQAVGIQNVSWNYDQSAVVATLHLSEATENNVAWQRFLPSGPIALLPLSDTL 266
Query 225 PAEQGLWQSIVWTLPDDYADEYSALSDHEFK---------------------ALL----- 258
S+VW+ ++A E ++ + +F A+L
Sbjct 267 -------SSLVWSTSHEHAAELVSMDEEKFVDAVNSAFWSDADHTDFIDTAGAMLQYAVS 319
Query 259 ----TRESQHMLGEVV---EVRSRAQFPLKARAAKQYVKEGLALIGDAAHVIHPLAGQGV 311
T+ S L V + +SR FPL A +YV+ +ALIGDAAH +HPLAGQGV
Sbjct 320 LLKPTKVSARQLPPSVARVDAKSRVLFPLGLGHAAEYVRPRVALIGDAAHRVHPLAGQGV 379
Query 312 NIGCLD----AAVLCDALLHDRARGVWAHEQTLRRYEHERKGQNDAMMHGMSIIGWLESQ 367
N+G D A L A + + G +H L YE ER+ N A++ ++ L S
Sbjct 380 NMGFGDISSLAHHLSTAAFNGKDLGSVSH---LTGYETERQRHNTALLAATDLLKRLYST 436
Query 368 EFFPLIALRNTGLRWVENSEILKNSFLQQAT 398
PL+ LR GL+ LK + A+
Sbjct 437 SASPLVLLRTWGLQATNAVSPLKEQIMAFAS 467
>A1KVW0 Ubiquinone hydroxylase UbiM [Neisseria meningitidis serogroup
C / serotype 2a (strain ATCC 700532 / DSM 15464 / FAM18)]
Length=461
Score = 120 bits (300), Expect = 4e-33
Identities = 104/403 (26%), Positives = 180/403 (45%), Gaps = 13/403 (3%)
Query 1 MTQIADVVIVGGGLVGGLTALLLAQGGVQATVLDAAPILDTAKVESVMNPRVLALSQATI 60
M+ +D+++VG G G A LA G++ T+++ +P+ T + R +AL+ +
Sbjct 68 MSLHSDILVVGAGPAGLSFAAELAGSGLKVTLIERSPL--TVLQNPPYDGREIALTHFSR 125
Query 61 HLLKTVEVWELISRQMPYTGMQVWNKNGYGDIQFGHHSASTPMIDQA--LGSMVEPSLLN 118
+++ + +W+ I Y NG D Q + + A LG ++ +
Sbjct 126 EIMQRLGMWDKIPENEIYPLRDAKVLNGRSDYQLHFPQPTEARGEPADCLGYLISNHNIR 185
Query 119 LAIQQKMRAVIQ-DYRTEVQVVQIEQLPNLWQIHLADGHCIQTRLLIGADGANSFVREKA 177
A + + + T+ V +++ N Q+ L +G + RLL+ AD S R +
Sbjct 186 RAAYEVVSQLDNVSILTDTVVKEVKTSDNEAQVILENGKILTARLLLAADSRFSQTRRQL 245
Query 178 MIDLDVLDYKQAAISCAIKTALSHEHVARQIFLPTGPLAFLPMASLVPAEQGLWQSIVWT 237
I D+ DY + C +K LS++H A + F +A LP+ E+ L +++ T
Sbjct 246 GISSDMHDYSRTMFVCRMKHTLSNQHTAYECFHYGRTIALLPL------EEHLTNTVI-T 298
Query 238 LPDDYADEYSALSDHEFKALLTRESQHMLGEVVEVRSRAQFPLKARAAKQYVKEGLALIG 297
+ D + LS E A + + + LG++ V S +PL AK++ + ALIG
Sbjct 299 VDTDKINSVQNLSPEELAASVKEQLKGRLGDMELVSSIHHYPLVGMIAKRFYGKRSALIG 358
Query 298 DAAHVIHPLAGQGVNIGCLDAAVLCDALLHDRARGV-WAHEQTLRRYEHERKGQNDAMMH 356
DAA +HP+ G N+G A +L +L RG L +Y ++ + H
Sbjct 359 DAAVGMHPVTAHGFNLGLSSADILAKLILEAEQRGQDIGASSLLEKYSNKHMLHAHPLYH 418
Query 357 GMSIIGWLESQEFFPLIALRNTGLRWVENSEILKNSFLQQATG 399
G +++ L + E P LR LR N LK +Q TG
Sbjct 419 GTNMMLKLFTNETAPAKLLRGLVLRAGNNFPPLKKLITKQLTG 461
>P25534 2-octaprenyl-6-methoxyphenol hydroxylase [Escherichia
coli (strain K12)]
Length=392
Score = 119 bits (297), Expect = 4e-33
Identities = 106/404 (26%), Positives = 181/404 (45%), Gaps = 29/404 (7%)
Query 7 VVIVGGGLVGGLTALLLAQGGVQATVLDAAPILDTAKVESVMNP----RVLALSQATIHL 62
V+IVGGG+ G AL +++ A + +++ ES +P R +AL+ T
Sbjct 3 VIIVGGGMAGATLALAISRLSHGALPVH---LIEATAPESHAHPGFDGRAIALAAGTCQQ 59
Query 63 LKTVEVWE-LISRQMPYTGMQVWNKNGYGDIQFGHHSASTPMIDQALGSMVEPSLLNLAI 121
L + VW+ L T + V ++ G + ALG +VE L N+
Sbjct 60 LARIGVWQSLADCATAITTVHVSDRGHAGFVTLAAEDYQLA----ALGQVVE--LHNVG- 112
Query 122 QQKMRAVIQD-----YRTEVQVVQIEQLPNLWQIHLADGHCIQTRLLIGADGANSFVREK 176
Q++ A+++ +V + + + ++ L G + R+L+ ADG +S +
Sbjct 113 -QRLFALLRKAPGVTLHCPDRVANVARTQSHVEVTLESGETLTGRVLVAADGTHSALATA 171
Query 177 AMIDLDVLDYKQAAISCAIKTALSHEHVARQIFLPTGPLAFLPMASLVPAEQGLWQSIVW 236
+D Y+Q A+ + T+++HE A + F GPLA LPM+ G S+VW
Sbjct 172 CGVDWQQEPYEQLAVIANVATSVAHEGRAFERFTQHGPLAMLPMSD------GRC-SLVW 224
Query 237 TLPDDYADEYSALSDHEFKALLTRESQHMLGEVVEVRSRAQFPLKARAAKQYVKEGLALI 296
P + +E + SD +F L LG++ R+ +PL A + + L+
Sbjct 225 CHPLERREEVLSWSDEKFCRELQSAFGWRLGKITHAGKRSAYPLALTHAARSITHRTVLV 284
Query 297 GDAAHVIHPLAGQGVNIGCLDAAVLCDALLHDRARGV-WAHEQTLRRYEHERKGQNDAMM 355
G+AA +HP+AGQG N+G D L + L + RG L RY+ R+ +A +
Sbjct 285 GNAAQTLHPIAGQGFNLGMRDVMSLAETLTQAQERGEDMGDYGVLCRYQQRRQSDREATI 344
Query 356 HGMSIIGWLESQEFFPLIALRNTGLRWVENSEILKNSFLQQATG 399
+ L + + PL+ RN GL +E ++ Q+ G
Sbjct 345 GVTDSLVHLFANRWAPLVVGRNIGLMTMELFTPARDVLAQRTLG 388
>P53318 Ubiquinone biosynthesis monooxygenase COQ6, mitochondrial
[Saccharomyces cerevisiae (strain ATCC 204508 / S288c)]
Length=479
Score = 101 bits (251), Expect = 1e-26
Identities = 122/465 (26%), Positives = 190/465 (41%), Gaps = 82/465 (18%)
Query 3 QIADVVIVGGGLVGGLTALLLAQG----GVQATVLDAAPILDTAKVESVMNP-------R 51
++ DV+IVGGG G A + ++ T++D + D K+ N R
Sbjct 26 KLTDVLIVGGGPAGLTLAASIKNSPQLKDLKTTLVDMVDLKD--KLSDFYNSPPDYFTNR 83
Query 52 VLALSQATIHLLKTVEVWELI-SRQMPYTGMQVWNKNGYGDIQFGHHSASTPMIDQALGS 110
+++++ +IH L+ L+ R Y G+ V + S +D A S
Sbjct 84 IVSVTPRSIHFLENNAGATLMHDRIQSYDGLYVTD------------GCSKATLDLARDS 131
Query 111 M--------VEPSLLNLAIQQKMRAVIQDYRTEVQVVQIEQL----PNLWQ-IHLADGHC 157
M ++ SL N Q + D +VV I+ P W + L++G
Sbjct 132 MLCMIEIINIQASLYNRISQYDSKKDSIDIIDNTKVVNIKHSDPNDPLSWPLVTLSNGEV 191
Query 158 IQTRLLIGADGANSFVREKAMIDLDVLDYKQAAISCAIKTALSHEHVAR-QIFLPTGPLA 216
+TRLL+GADG NS R + I Y + ++K + Q FLPTGP+A
Sbjct 192 YKTRLLVGADGFNSPTRRFSQIPSRGWMYNAYGVVASMKLEYPPFKLRGWQRFLPTGPIA 251
Query 217 FLPM----ASLVPAEQGLWQSIVWTLP---------------------------DDYADE 245
LPM A+LV + ++ +LP D D
Sbjct 252 HLPMPENNATLVWSSSERLSRLLLSLPPESFTALINAAFVLEDADMNYYYRTLEDGSMDT 311
Query 246 YSALSDHEFKA---LLTRESQHMLGEVVEVR-------SRAQFPLKARAAKQYVKEGLAL 295
+ D +F+ T + + + E+ R +RA+FPLK A +Y + +AL
Sbjct 312 DKLIEDIKFRTEEIYATLKDESDIDEIYPPRVVSIIDKTRARFPLKLTHADRYCTDRVAL 371
Query 296 IGDAAHVIHPLAGQGVNIGCLDAAVLCDALLHDRARGV-WAHEQTLRRYEHERKGQNDAM 354
+GDAAH HPLAGQG+N+G D L AL RG+ +L + ER N+ +
Sbjct 372 VGDAAHTTHPLAGQGLNMGQTDVHGLVYALEKAMERGLDIGSSLSLEPFWAERYPSNNVL 431
Query 355 MHGMSIIGWLESQEFFPLIALRNTGLRWVENSEILKNSFLQQATG 399
+ + L F P++ALR GL +KN + G
Sbjct 432 LGMADKLFKLYHTNFPPVVALRTFGLNLTNKIGPVKNMIIDTLGG 476
>C1I201 Para-nitrophenol 4-monooxygenase [Pseudomonas sp. (strain
WBC-3)]
Length=403
Score = 73.2 bits (178), Expect = 2e-17
Identities = 88/366 (24%), Positives = 155/366 (42%), Gaps = 47/366 (13%)
Query 1 MTQIADVVIVGGGLVGGLTALLLAQGGVQATVLDAAP-ILDTAKVESVMNPRVLALSQAT 59
M + VV+VGGG VG LTAL L + G++ VL+A P + + + + M P AL +
Sbjct 1 METLDGVVVVGGGPVGLLTALKLGKAGIKVVVLEAEPGVSPSPRAVAYMPPTAAALDR-- 58
Query 60 IHLLKTVEVWELISRQMPYTGMQVWNKNGYGDIQFGHHSASTPMIDQALGSMVEPSLLNL 119
LL+ + ++ Y ++G G++ M L + + L
Sbjct 59 FGLLQDIRKRAVMCPDFAY-------RHGNGEL-------IAKMDWSVLSQDTQYPYMLL 104
Query 120 AIQQKMRAVIQDYRTEVQVVQIEQLPNLWQIHLADGHC------------IQTRLLIGAD 167
Q + VI + E+ V+I + ++ D + ++ R L D
Sbjct 105 LGQNHVSNVIFQHLRELPNVEIRWNHRVEEVDQDDAYVTIETSSPGGTSRLRARWLAATD 164
Query 168 GANSFVREKAMIDLDVLDYKQAAISCAIKTALSHEHVARQIFLPTGPLAFLPMASLVPAE 227
GA S VR+K + D + + + ++ + S +R F+ P+ + + L +
Sbjct 165 GARSTVRQKIGLTFDGITWDERLVATNVFYDFSLHGYSRANFVHD-PVDWAVVVQL--DK 221
Query 228 QGLWQSIVWTLPDDYADEYSALSDHEFKALLTRESQHMLG-----EVVEVRSRAQFPLKA 282
GLW+ E ++LSD E + L + +L + V + +
Sbjct 222 TGLWRVCY--------GEDASLSDAEVRRRLPERFKRLLPGAPTPDQYRVDHLNPYRVHQ 273
Query 283 RAAKQYVKEGLALIGDAAHVIHPLAGQGVNIGCLDAAVLCDALLHDRARGVWAHEQTLRR 342
R A ++ + + L GDAAH +P+ G G++ G LDA L +AL+ G A +TL
Sbjct 274 RCAAEFRRGRVVLAGDAAHATNPMGGLGLSGGVLDAEHLAEALIAVIKNG--ASTKTLDE 331
Query 343 YEHERK 348
Y +R+
Sbjct 332 YSIDRR 337
Lambda K H a alpha
0.322 0.135 0.403 0.792 4.96
Gapped
Lambda K H a alpha sigma
0.267 0.0410 0.140 1.90 42.6 43.6
Effective search space used: 1992359
Database: 9779d6877d2fe68a4582dbd9d4ff6267.SwissProt.fasta
Posted date: May 9, 2024 3:10 PM
Number of letters in database: 6,219
Number of sequences in database: 14
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Neighboring words threshold: 11
Window for multiple hits: 40
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Data ...
