BLASTP 2.12.0+


Reference: Stephen F. Altschul, Thomas L. Madden, Alejandro A.
Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J.
Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of
protein database search programs", Nucleic Acids Res. 25:3389-3402.


Reference for composition-based statistics: Alejandro A. Schaffer,
L. Aravind, Thomas L. Madden, Sergei Shavirin, John L. Spouge, Yuri
I. Wolf, Eugene V. Koonin, and Stephen F. Altschul (2001),
"Improving the accuracy of PSI-BLAST protein database searches with
composition-based statistics and other refinements", Nucleic Acids
Res. 29:2994-3005.



Database: e65442465cec5c930b4369f7327ba964.SwissProt.fasta
           23 sequences; 10,036 total letters



Query= ACIAD1151

Length=447
                                                                      Score     E
Sequences producing significant alignments:                          (Bits)  Value

A3M3K6 Argininosuccinate synthase [Acinetobacter baumannii (strai...  859     0.0  
A1KWJ8 Argininosuccinate synthase [Neisseria meningitidis serogro...  768     0.0  
A9M4B1 Argininosuccinate synthase [Neisseria meningitidis serogro...  768     0.0  
Q9JWM1 Argininosuccinate synthase [Neisseria meningitidis serogro...  768     0.0  
B4RQS8 Argininosuccinate synthase [Neisseria gonorrhoeae (strain ...  768     0.0  
Q5F5G5 Argininosuccinate synthase [Neisseria gonorrhoeae (strain ...  768     0.0  
Q9JXC1 Argininosuccinate synthase [Neisseria meningitidis serogro...  766     0.0  
P44315 Argininosuccinate synthase [Haemophilus influenzae (strain...  752     0.0  
A5UFF8 Argininosuccinate synthase [Haemophilus influenzae (strain...  752     0.0  
A5UBF3 Argininosuccinate synthase [Haemophilus influenzae (strain...  751     0.0  
Q4QJM0 Argininosuccinate synthase [Haemophilus influenzae (strain...  751     0.0  
B2UBA3 Argininosuccinate synthase [Ralstonia pickettii (strain 12J)]  744     0.0  
Q8XWC1 Argininosuccinate synthase [Ralstonia nicotianae (strain G...  744     0.0  
P0A6E4 Argininosuccinate synthase [Escherichia coli (strain K12)]     705     0.0  
P0C1A1 Argininosuccinate synthase [Dickeya dadantii (strain 3937)]    700     0.0  
Q06734 Argininosuccinate synthase [Streptomyces lavendulae]           577     0.0  
P59846 Argininosuccinate synthase [Thermus thermophilus (strain A...  172     3e-52
Q93JQ8 Argininosuccinate synthase [Rhodococcus fascians]              159     3e-47
P16460 Argininosuccinate synthase [Mus musculus]                      155     7e-46
P14568 Argininosuccinate synthase [Bos taurus]                        155     1e-45
P22768 Argininosuccinate synthase [Saccharomyces cerevisiae (stra...  155     1e-45
P00966 Argininosuccinate synthase [Homo sapiens]                      153     4e-45
P09034 Argininosuccinate synthase [Rattus norvegicus]                 152     1e-44


>A3M3K6 Argininosuccinate synthase [Acinetobacter baumannii (strain 
ATCC 17978 / CIP 53.77 / LMG 1025 / NCDC KC755 / 5377)]
Length=447

 Score = 859 bits (2220),  Expect = 0.0
 Identities = 423/446 (95%), Positives = 438/446 (98%), Gaps = 0/446 (0%)

Query  1    MTDNATILQHVPVGKKVGIAFSGGLDTSAALLWMKQKGAEPYAYTANLGQPDEDDYDAIP  60
            MTDNATILQHVPVGKKVGIAFSGGLDTSAALLWMKQKGAEPYAYTANLGQPDEDDYDAIP
Sbjct  1    MTDNATILQHVPVGKKVGIAFSGGLDTSAALLWMKQKGAEPYAYTANLGQPDEDDYDAIP  60

Query  61   KKAEQYGAVKARLIDCRLQLALEGIAAIQCGAFHISTGGVPYFNTTPLGRAVTGTMLVTA  120
            KKAEQYGAVKARLIDCRLQLALEGIAAIQCGAFHISTGGVPYFNTTPLGRAVTGTMLVTA
Sbjct  61   KKAEQYGAVKARLIDCRLQLALEGIAAIQCGAFHISTGGVPYFNTTPLGRAVTGTMLVTA  120

Query  121  MKEDDVNIWGDGSTYKGNDIERFYRYGLLTNPNLKIYKPWLDQTFIDELGGRAEMSQFLI  180
            MKEDDVNIWGDGSTYKGNDIERFYRYGLLTNPNLKIYKPWLDQ FIDELGGRAEMSQFLI
Sbjct  121  MKEDDVNIWGDGSTYKGNDIERFYRYGLLTNPNLKIYKPWLDQNFIDELGGRAEMSQFLI  180

Query  181  DNGFDYKMSKEKAYSTDSNMLGATHEAKDLEYLDAGIKIVDPIMGVAFWKDEVEIQPEQV  240
            DNGFDYKMSKEKAYSTDSNMLGATHEAKDLEYL+AGIKI DPI+GVAFWK+EVEI+PE+V
Sbjct  181  DNGFDYKMSKEKAYSTDSNMLGATHEAKDLEYLNAGIKIRDPIIGVAFWKEEVEIKPEEV  240

Query  241  SITFEEGMPVALNGQRIEDPVEFILEANRIGGRHGLGMSDQIENRIIEAKSRGIYEAPGM  300
            ++ FEEG+PVALNGQR ++PVE ILEANRIGGRHGLGMSDQIENRIIEAKSRGIYEAPGM
Sbjct  241  TVRFEEGVPVALNGQRFDNPVELILEANRIGGRHGLGMSDQIENRIIEAKSRGIYEAPGM  300

Query  301  ALLHIAYERLVTGIHNEDTIEQYRINGLRLGRLLYQGRWFDSQSLMLRETAQRWVAKAIT  360
            ALLHIAYERLVTGIHNEDTIEQYRINGLRLGRLLYQGRWFDSQ+LMLRETAQRWVAKAIT
Sbjct  301  ALLHIAYERLVTGIHNEDTIEQYRINGLRLGRLLYQGRWFDSQALMLRETAQRWVAKAIT  360

Query  361  GTVTLELRRGNDYTIMNTESPNLTYEAERLTMEKGDSMFSPMDRIGQLTMRNLDITDTRA  420
            G VTLELRRGNDYTIMNTESPNLTYEAERLTMEKGDSMF+PMDRIGQLTMRNLDITDTRA
Sbjct  361  GEVTLELRRGNDYTIMNTESPNLTYEAERLTMEKGDSMFTPMDRIGQLTMRNLDITDTRA  420

Query  421  KLGIYTNSGLLSIGHGSAVPQLETKK  446
            KLGIYT++GLLSIG GSAVPQL+ KK
Sbjct  421  KLGIYTDAGLLSIGQGSAVPQLDNKK  446


>A1KWJ8 Argininosuccinate synthase [Neisseria meningitidis serogroup 
C / serotype 2a (strain ATCC 700532 / DSM 15464 / FAM18)]
Length=447

 Score = 768 bits (1984),  Expect = 0.0
 Identities = 378/447 (85%), Positives = 411/447 (92%), Gaps = 1/447 (0%)

Query  1    MTDNATILQHVPVGKKVGIAFSGGLDTSAALLWMKQKGAEPYAYTANLGQPDEDDYDAIP  60
            M+ N TILQ++PVG+KVGIAFSGGLDTSAALLWMK KGA PYAYTANLGQPDEDDY+AIP
Sbjct  1    MSQNHTILQNLPVGQKVGIAFSGGLDTSAALLWMKLKGALPYAYTANLGQPDEDDYNAIP  60

Query  61   KKAEQYGAVKARLIDCRLQLALEGIAAIQCGAFHISTGGVPYFNTTPLGRAVTGTMLVTA  120
            KKA +YGA  ARLIDCR QLA EGIAAIQCGAFH+STGG+ YFNTTPLGRAVTGTMLV+A
Sbjct  61   KKAMEYGAENARLIDCRAQLAHEGIAAIQCGAFHVSTGGIAYFNTTPLGRAVTGTMLVSA  120

Query  121  MKEDDVNIWGDGSTYKGNDIERFYRYGLLTNPNLKIYKPWLDQTFIDELGGRAEMSQFLI  180
            MKEDDVNIWGDGSTYKGNDIERFYRYGLLTNP LKIYKPWLDQ FIDELGGR EMS+FLI
Sbjct  121  MKEDDVNIWGDGSTYKGNDIERFYRYGLLTNPALKIYKPWLDQQFIDELGGRHEMSEFLI  180

Query  181  DNGFDYKMSKEKAYSTDSNMLGATHEAKDLEYLDAGIKIVDPIMGVAFWKDEVEIQPEQV  240
             NGF+YKMS EKAYSTDSNMLGATHEAKDLE+L++GIKIV PIMGVAFW + VE+ PE+V
Sbjct  181  ANGFNYKMSVEKAYSTDSNMLGATHEAKDLEFLNSGIKIVKPIMGVAFWDENVEVSPEEV  240

Query  241  SITFEEGMPVALNGQRIEDPVEFILEANRIGGRHGLGMSDQIENRIIEAKSRGIYEAPGM  300
            S+ FEEG+PVALNG+   DPVE  LEANRIGGRHGLGMSDQIENRIIEAKSRGIYEAPGM
Sbjct  241  SVRFEEGVPVALNGKEYADPVELFLEANRIGGRHGLGMSDQIENRIIEAKSRGIYEAPGM  300

Query  301  ALLHIAYERLVTGIHNEDTIEQYRINGLRLGRLLYQGRWFDSQSLMLRETAQRWVAKAIT  360
            AL HIAYERLVTGIHNEDTIEQYRINGLRLGRLLYQGRWFDSQ+LMLRETAQRWVAKA+T
Sbjct  301  ALFHIAYERLVTGIHNEDTIEQYRINGLRLGRLLYQGRWFDSQALMLRETAQRWVAKAVT  360

Query  361  GTVTLELRRGNDYTIMNTESPNLTYEAERLTMEKGD-SMFSPMDRIGQLTMRNLDITDTR  419
            G VTLELRRGNDY+I+NTESPNLTY+ ERL+MEK + + F+P+DRIGQLTMRNLDITDTR
Sbjct  361  GEVTLELRRGNDYSILNTESPNLTYQPERLSMEKVEGAAFTPLDRIGQLTMRNLDITDTR  420

Query  420  AKLGIYTNSGLLSIGHGSAVPQLETKK  446
            AKLGIY+ SGLLS+G GS +PQL  KK
Sbjct  421  AKLGIYSQSGLLSLGEGSVLPQLGNKK  447


>A9M4B1 Argininosuccinate synthase [Neisseria meningitidis serogroup 
C (strain 053442)]
Length=447

 Score = 768 bits (1984),  Expect = 0.0
 Identities = 379/447 (85%), Positives = 410/447 (92%), Gaps = 1/447 (0%)

Query  1    MTDNATILQHVPVGKKVGIAFSGGLDTSAALLWMKQKGAEPYAYTANLGQPDEDDYDAIP  60
            M+ N TILQ +PVG+KVGIAFSGGLDTSAALLWMK KGA PYAYTANLGQPDEDDY+AIP
Sbjct  1    MSQNHTILQSLPVGQKVGIAFSGGLDTSAALLWMKLKGALPYAYTANLGQPDEDDYNAIP  60

Query  61   KKAEQYGAVKARLIDCRLQLALEGIAAIQCGAFHISTGGVPYFNTTPLGRAVTGTMLVTA  120
            KKA +YGA  ARLIDCR QLA EGIAAIQCGAFH+STGG+ YFNTTPLGRAVTGTMLV+A
Sbjct  61   KKAMEYGAENARLIDCRAQLAHEGIAAIQCGAFHVSTGGIAYFNTTPLGRAVTGTMLVSA  120

Query  121  MKEDDVNIWGDGSTYKGNDIERFYRYGLLTNPNLKIYKPWLDQTFIDELGGRAEMSQFLI  180
            MKEDDVNIWGDGSTYKGNDIERFYRYGLLTNP LKIYKPWLDQ FIDELGGR EMS+FLI
Sbjct  121  MKEDDVNIWGDGSTYKGNDIERFYRYGLLTNPALKIYKPWLDQQFIDELGGRHEMSEFLI  180

Query  181  DNGFDYKMSKEKAYSTDSNMLGATHEAKDLEYLDAGIKIVDPIMGVAFWKDEVEIQPEQV  240
             NGF+YKMS EKAYSTDSNMLGATHEAKDLE+L++GIKIV PIMGVAFW + VE+ PE+V
Sbjct  181  ANGFNYKMSVEKAYSTDSNMLGATHEAKDLEFLNSGIKIVKPIMGVAFWDENVEVSPEEV  240

Query  241  SITFEEGMPVALNGQRIEDPVEFILEANRIGGRHGLGMSDQIENRIIEAKSRGIYEAPGM  300
            S+ FEEG+PVALNG+   DPVE  LEANRIGGRHGLGMSDQIENRIIEAKSRGIYEAPGM
Sbjct  241  SVRFEEGVPVALNGKEYADPVELFLEANRIGGRHGLGMSDQIENRIIEAKSRGIYEAPGM  300

Query  301  ALLHIAYERLVTGIHNEDTIEQYRINGLRLGRLLYQGRWFDSQSLMLRETAQRWVAKAIT  360
            AL HIAYERLVTGIHNEDTIEQYRINGLRLGRLLYQGRWFDSQ+LMLRETAQRWVAKAIT
Sbjct  301  ALFHIAYERLVTGIHNEDTIEQYRINGLRLGRLLYQGRWFDSQALMLRETAQRWVAKAIT  360

Query  361  GTVTLELRRGNDYTIMNTESPNLTYEAERLTMEK-GDSMFSPMDRIGQLTMRNLDITDTR  419
            G VTLELRRGNDY+I+NTESPNLTY+ ERL+MEK  D+ F+P+DRIGQLTMRNLDITDTR
Sbjct  361  GEVTLELRRGNDYSILNTESPNLTYQPERLSMEKVEDAAFTPLDRIGQLTMRNLDITDTR  420

Query  420  AKLGIYTNSGLLSIGHGSAVPQLETKK  446
            AKLGIY+ SGLLS+G GS +PQL  K+
Sbjct  421  AKLGIYSQSGLLSLGEGSVLPQLGNKQ  447


>Q9JWM1 Argininosuccinate synthase [Neisseria meningitidis serogroup 
A / serotype 4A (strain DSM 15465 / Z2491)]
Length=447

 Score = 768 bits (1983),  Expect = 0.0
 Identities = 378/447 (85%), Positives = 411/447 (92%), Gaps = 1/447 (0%)

Query  1    MTDNATILQHVPVGKKVGIAFSGGLDTSAALLWMKQKGAEPYAYTANLGQPDEDDYDAIP  60
            M  N TILQ++PVG+KVGIAFSGGLDTSAALLWMK KGA PYAYTANLGQPDEDDY+AIP
Sbjct  1    MNQNHTILQNLPVGQKVGIAFSGGLDTSAALLWMKLKGALPYAYTANLGQPDEDDYNAIP  60

Query  61   KKAEQYGAVKARLIDCRLQLALEGIAAIQCGAFHISTGGVPYFNTTPLGRAVTGTMLVTA  120
            KKA +YGA  ARLIDCR QLA EGIAAIQCGAFH+STGG+ YFNTTPLGRAVTGTMLV+A
Sbjct  61   KKAMEYGAENARLIDCRAQLAHEGIAAIQCGAFHVSTGGIAYFNTTPLGRAVTGTMLVSA  120

Query  121  MKEDDVNIWGDGSTYKGNDIERFYRYGLLTNPNLKIYKPWLDQTFIDELGGRAEMSQFLI  180
            MKEDDVNIWGDGSTYKGNDIERFYRYGLLTNP LKIYKPWLDQ FIDELGGR EMS+FLI
Sbjct  121  MKEDDVNIWGDGSTYKGNDIERFYRYGLLTNPALKIYKPWLDQQFIDELGGRHEMSEFLI  180

Query  181  DNGFDYKMSKEKAYSTDSNMLGATHEAKDLEYLDAGIKIVDPIMGVAFWKDEVEIQPEQV  240
             NGF+YKMS EKAYSTDSNMLGATHEAKDLE+L++GIKIV PIMG+AFW + VEI+PE+V
Sbjct  181  ANGFNYKMSVEKAYSTDSNMLGATHEAKDLEFLNSGIKIVKPIMGIAFWDENVEIKPEEV  240

Query  241  SITFEEGMPVALNGQRIEDPVEFILEANRIGGRHGLGMSDQIENRIIEAKSRGIYEAPGM  300
            S+ FEEG+PVALNG+   DPVE  LEANRIGGRHGLGMSDQIENRIIEAKSRGIYEAPGM
Sbjct  241  SVRFEEGVPVALNGKEYADPVELFLEANRIGGRHGLGMSDQIENRIIEAKSRGIYEAPGM  300

Query  301  ALLHIAYERLVTGIHNEDTIEQYRINGLRLGRLLYQGRWFDSQSLMLRETAQRWVAKAIT  360
            AL HIAYERLVTGIHNEDTIEQYRINGLRLGRLLYQGRWFDSQ+LMLRETAQRWVAKAIT
Sbjct  301  ALFHIAYERLVTGIHNEDTIEQYRINGLRLGRLLYQGRWFDSQALMLRETAQRWVAKAIT  360

Query  361  GTVTLELRRGNDYTIMNTESPNLTYEAERLTMEK-GDSMFSPMDRIGQLTMRNLDITDTR  419
            G VTLELRRGNDY+I+NTESPNLTY+ ERL+MEK  D+ F+P+DRIGQLTMRNLDITDTR
Sbjct  361  GEVTLELRRGNDYSILNTESPNLTYQPERLSMEKVEDAAFTPLDRIGQLTMRNLDITDTR  420

Query  420  AKLGIYTNSGLLSIGHGSAVPQLETKK  446
            AKLGIY+ SGLL++G GS +PQL  K+
Sbjct  421  AKLGIYSQSGLLALGEGSVLPQLGNKQ  447


>B4RQS8 Argininosuccinate synthase [Neisseria gonorrhoeae (strain 
NCCP11945)]
Length=447

 Score = 768 bits (1982),  Expect = 0.0
 Identities = 378/447 (85%), Positives = 411/447 (92%), Gaps = 1/447 (0%)

Query  1    MTDNATILQHVPVGKKVGIAFSGGLDTSAALLWMKQKGAEPYAYTANLGQPDEDDYDAIP  60
            M  N TILQ++PVG+KVGIAFSGGLDTSAALLWMK KGA PYAYTANLGQPDEDDY+AIP
Sbjct  1    MNQNHTILQNLPVGQKVGIAFSGGLDTSAALLWMKLKGALPYAYTANLGQPDEDDYNAIP  60

Query  61   KKAEQYGAVKARLIDCRLQLALEGIAAIQCGAFHISTGGVPYFNTTPLGRAVTGTMLVTA  120
            KKA +YGA  ARLIDCR QLA EGIAAIQCGAFH+STGG+ YFNTTPLGRAVTGTMLV+A
Sbjct  61   KKAMEYGAENARLIDCRAQLAHEGIAAIQCGAFHVSTGGIAYFNTTPLGRAVTGTMLVSA  120

Query  121  MKEDDVNIWGDGSTYKGNDIERFYRYGLLTNPNLKIYKPWLDQTFIDELGGRAEMSQFLI  180
            MKEDDVNIWGDGSTYKGNDIERFYRYGLLTNP LKIYKPWLDQ FIDELGGR EMS+FLI
Sbjct  121  MKEDDVNIWGDGSTYKGNDIERFYRYGLLTNPALKIYKPWLDQQFIDELGGRHEMSEFLI  180

Query  181  DNGFDYKMSKEKAYSTDSNMLGATHEAKDLEYLDAGIKIVDPIMGVAFWKDEVEIQPEQV  240
             NGF+YKMS EKAYSTDSNMLGATHEAKDLE+L++GIKIV PIMGVAFW + VEI+PE+V
Sbjct  181  ANGFNYKMSVEKAYSTDSNMLGATHEAKDLEFLNSGIKIVKPIMGVAFWDENVEIEPEEV  240

Query  241  SITFEEGMPVALNGQRIEDPVEFILEANRIGGRHGLGMSDQIENRIIEAKSRGIYEAPGM  300
            S+ FEEG+PVALNG+   DPVE  LEANRIGGRHGLGMSDQIENRIIEAKSRGIYEAPGM
Sbjct  241  SVRFEEGVPVALNGKEYADPVELFLEANRIGGRHGLGMSDQIENRIIEAKSRGIYEAPGM  300

Query  301  ALLHIAYERLVTGIHNEDTIEQYRINGLRLGRLLYQGRWFDSQSLMLRETAQRWVAKAIT  360
            AL HIAYERLVTGIHNEDTIEQYRINGLRLGRLLYQGRWFDSQ+LMLRETAQRWVAKA+T
Sbjct  301  ALFHIAYERLVTGIHNEDTIEQYRINGLRLGRLLYQGRWFDSQALMLRETAQRWVAKAVT  360

Query  361  GTVTLELRRGNDYTIMNTESPNLTYEAERLTMEKGD-SMFSPMDRIGQLTMRNLDITDTR  419
            G VTLELRRGNDY+I+NTESPNLTY+ ERL+MEK + + F+P+DRIGQLTMRNLDITDTR
Sbjct  361  GEVTLELRRGNDYSILNTESPNLTYQPERLSMEKVEGAAFTPLDRIGQLTMRNLDITDTR  420

Query  420  AKLGIYTNSGLLSIGHGSAVPQLETKK  446
            AKLGIY+ SGLLS+G GS +PQL  K+
Sbjct  421  AKLGIYSQSGLLSLGEGSVLPQLGNKQ  447


>Q5F5G5 Argininosuccinate synthase [Neisseria gonorrhoeae (strain 
ATCC 700825 / FA 1090)]
Length=447

 Score = 768 bits (1982),  Expect = 0.0
 Identities = 378/447 (85%), Positives = 411/447 (92%), Gaps = 1/447 (0%)

Query  1    MTDNATILQHVPVGKKVGIAFSGGLDTSAALLWMKQKGAEPYAYTANLGQPDEDDYDAIP  60
            M  N TILQ++PVG+KVGIAFSGGLDTSAALLWMK KGA PYAYTANLGQPDEDDY+AIP
Sbjct  1    MNQNHTILQNLPVGQKVGIAFSGGLDTSAALLWMKLKGALPYAYTANLGQPDEDDYNAIP  60

Query  61   KKAEQYGAVKARLIDCRLQLALEGIAAIQCGAFHISTGGVPYFNTTPLGRAVTGTMLVTA  120
            KKA +YGA  ARLIDCR QLA EGIAAIQCGAFH+STGG+ YFNTTPLGRAVTGTMLV+A
Sbjct  61   KKAMEYGAENARLIDCRAQLAHEGIAAIQCGAFHVSTGGIAYFNTTPLGRAVTGTMLVSA  120

Query  121  MKEDDVNIWGDGSTYKGNDIERFYRYGLLTNPNLKIYKPWLDQTFIDELGGRAEMSQFLI  180
            MKEDDVNIWGDGSTYKGNDIERFYRYGLLTNP LKIYKPWLDQ FIDELGGR EMS+FLI
Sbjct  121  MKEDDVNIWGDGSTYKGNDIERFYRYGLLTNPALKIYKPWLDQQFIDELGGRHEMSEFLI  180

Query  181  DNGFDYKMSKEKAYSTDSNMLGATHEAKDLEYLDAGIKIVDPIMGVAFWKDEVEIQPEQV  240
             NGF+YKMS EKAYSTDSNMLGATHEAKDLE+L++GIKIV PIMGVAFW + VEI+PE+V
Sbjct  181  ANGFNYKMSVEKAYSTDSNMLGATHEAKDLEFLNSGIKIVKPIMGVAFWDENVEIEPEEV  240

Query  241  SITFEEGMPVALNGQRIEDPVEFILEANRIGGRHGLGMSDQIENRIIEAKSRGIYEAPGM  300
            S+ FEEG+PVALNG+   DPVE  LEANRIGGRHGLGMSDQIENRIIEAKSRGIYEAPGM
Sbjct  241  SVRFEEGVPVALNGKEYADPVELFLEANRIGGRHGLGMSDQIENRIIEAKSRGIYEAPGM  300

Query  301  ALLHIAYERLVTGIHNEDTIEQYRINGLRLGRLLYQGRWFDSQSLMLRETAQRWVAKAIT  360
            AL HIAYERLVTGIHNEDTIEQYRINGLRLGRLLYQGRWFDSQ+LMLRETAQRWVAKA+T
Sbjct  301  ALFHIAYERLVTGIHNEDTIEQYRINGLRLGRLLYQGRWFDSQALMLRETAQRWVAKAVT  360

Query  361  GTVTLELRRGNDYTIMNTESPNLTYEAERLTMEKGD-SMFSPMDRIGQLTMRNLDITDTR  419
            G VTLELRRGNDY+I+NTESPNLTY+ ERL+MEK + + F+P+DRIGQLTMRNLDITDTR
Sbjct  361  GEVTLELRRGNDYSILNTESPNLTYQPERLSMEKVEGAAFTPLDRIGQLTMRNLDITDTR  420

Query  420  AKLGIYTNSGLLSIGHGSAVPQLETKK  446
            AKLGIY+ SGLLS+G GS +PQL  K+
Sbjct  421  AKLGIYSQSGLLSLGEGSVLPQLGNKQ  447


>Q9JXC1 Argininosuccinate synthase [Neisseria meningitidis serogroup 
B (strain MC58)]
Length=447

 Score = 766 bits (1979),  Expect = 0.0
 Identities = 377/447 (84%), Positives = 409/447 (91%), Gaps = 1/447 (0%)

Query  1    MTDNATILQHVPVGKKVGIAFSGGLDTSAALLWMKQKGAEPYAYTANLGQPDEDDYDAIP  60
            M+ N TILQ +PVG+KVGIAFSGGLDTSAALLWMK KGA PYAYTANLGQPDEDDY+AIP
Sbjct  1    MSQNHTILQSLPVGQKVGIAFSGGLDTSAALLWMKLKGALPYAYTANLGQPDEDDYNAIP  60

Query  61   KKAEQYGAVKARLIDCRLQLALEGIAAIQCGAFHISTGGVPYFNTTPLGRAVTGTMLVTA  120
            KKA +YGA  ARLIDCR QLA EGIAAIQCGAFH+STGG+ YFNTTPLGRAVTGTMLV+A
Sbjct  61   KKAMEYGAENARLIDCRAQLAHEGIAAIQCGAFHVSTGGIAYFNTTPLGRAVTGTMLVSA  120

Query  121  MKEDDVNIWGDGSTYKGNDIERFYRYGLLTNPNLKIYKPWLDQTFIDELGGRAEMSQFLI  180
            MKEDDVNIWGDGSTYKGNDIERFYRYGLLTNP LKIYKPWLDQ FIDELGGR EMS+FLI
Sbjct  121  MKEDDVNIWGDGSTYKGNDIERFYRYGLLTNPALKIYKPWLDQQFIDELGGRHEMSEFLI  180

Query  181  DNGFDYKMSKEKAYSTDSNMLGATHEAKDLEYLDAGIKIVDPIMGVAFWKDEVEIQPEQV  240
             NGF+YKMS EKAYSTDSNMLGATHEAKDLE+L++GIKIV PIMGVAFW + VE+ PE+V
Sbjct  181  ANGFNYKMSVEKAYSTDSNMLGATHEAKDLEFLNSGIKIVKPIMGVAFWDENVEVSPEEV  240

Query  241  SITFEEGMPVALNGQRIEDPVEFILEANRIGGRHGLGMSDQIENRIIEAKSRGIYEAPGM  300
            S+ FEEG+PVALNG+   DPVE  LEANRIGGRHGLGMSDQIENRIIEAKSRGIYEAPGM
Sbjct  241  SVRFEEGVPVALNGKEYADPVELFLEANRIGGRHGLGMSDQIENRIIEAKSRGIYEAPGM  300

Query  301  ALLHIAYERLVTGIHNEDTIEQYRINGLRLGRLLYQGRWFDSQSLMLRETAQRWVAKAIT  360
            AL HIAYERLVTGIHNEDTIEQYRINGLRLGRLLYQGRWFDSQ+LMLRETAQRWVAKA+T
Sbjct  301  ALFHIAYERLVTGIHNEDTIEQYRINGLRLGRLLYQGRWFDSQALMLRETAQRWVAKAVT  360

Query  361  GTVTLELRRGNDYTIMNTESPNLTYEAERLTMEK-GDSMFSPMDRIGQLTMRNLDITDTR  419
            G VTLELRRGNDY+I+NTESPNLTY+ ERL+MEK  D+ F+P+DRIGQLTMRNLDITDTR
Sbjct  361  GEVTLELRRGNDYSILNTESPNLTYQPERLSMEKVEDAAFTPLDRIGQLTMRNLDITDTR  420

Query  420  AKLGIYTNSGLLSIGHGSAVPQLETKK  446
             KLGIY+ SGLLS+G GS +PQL  K+
Sbjct  421  VKLGIYSQSGLLSLGEGSVLPQLGNKQ  447


>P44315 Argininosuccinate synthase [Haemophilus influenzae (strain 
ATCC 51907 / DSM 11121 / KW20 / Rd)]
Length=444

 Score = 752 bits (1941),  Expect = 0.0
 Identities = 371/441 (84%), Positives = 403/441 (91%), Gaps = 1/441 (0%)

Query  6    TILQHVPVGKKVGIAFSGGLDTSAALLWMKQKGAEPYAYTANLGQPDEDDYDAIPKKAEQ  65
            TILQ++P G+KVGIAFSGGLDTSAALLWM+QKGA PYAYTANLGQPDEDDY+AIPKKA  
Sbjct  4    TILQNLPKGQKVGIAFSGGLDTSAALLWMRQKGAVPYAYTANLGQPDEDDYNAIPKKAMA  63

Query  66   YGAVKARLIDCRLQLALEGIAAIQCGAFHISTGGVPYFNTTPLGRAVTGTMLVTAMKEDD  125
            YGA  ARLIDCR QLA EGIAAIQCGAFHISTGG+PYFNTTPLGRAVTGTMLV AMKEDD
Sbjct  64   YGAENARLIDCRAQLAHEGIAAIQCGAFHISTGGIPYFNTTPLGRAVTGTMLVAAMKEDD  123

Query  126  VNIWGDGSTYKGNDIERFYRYGLLTNPNLKIYKPWLDQTFIDELGGRAEMSQFLIDNGFD  185
            VNIWGDGST+KGNDIERFYRYGLLTNPNLKIYKPWLD  FI+ELGGR EMSQFLI+NGFD
Sbjct  124  VNIWGDGSTFKGNDIERFYRYGLLTNPNLKIYKPWLDVQFIEELGGRLEMSQFLIENGFD  183

Query  186  YKMSKEKAYSTDSNMLGATHEAKDLEYLDAGIKIVDPIMGVAFWKDEVEIQPEQVSITFE  245
            YKMS EKAYSTDSNMLGATHEAKDLE L  G+KIV PIMGVAFW ++VEI+PE V++TFE
Sbjct  184  YKMSVEKAYSTDSNMLGATHEAKDLEQLSTGMKIVKPIMGVAFWDEKVEIKPETVTVTFE  243

Query  246  EGMPVALNGQRIEDPVEFILEANRIGGRHGLGMSDQIENRIIEAKSRGIYEAPGMALLHI  305
            +G+PVALNG+  ++ V+ ILEANRIGGRHGLGMSDQIENRIIEAKSRGIYEAPGMALLHI
Sbjct  244  DGVPVALNGKHFDNAVDLILEANRIGGRHGLGMSDQIENRIIEAKSRGIYEAPGMALLHI  303

Query  306  AYERLVTGIHNEDTIEQYRINGLRLGRLLYQGRWFDSQSLMLRETAQRWVAKAITGTVTL  365
            AYERLVTGIHNEDTIEQYRING+RLGRLLYQGRWFD Q+LMLRETAQRWVAKAITGTVTL
Sbjct  304  AYERLVTGIHNEDTIEQYRINGIRLGRLLYQGRWFDPQALMLRETAQRWVAKAITGTVTL  363

Query  366  ELRRGNDYTIMNTESPNLTYEAERLTMEK-GDSMFSPMDRIGQLTMRNLDITDTRAKLGI  424
            ELRRGND+TI+NTESPNLTYEAERL+MEK  D+ F P+DRIGQLTMRNLD++DTR KLGI
Sbjct  364  ELRRGNDFTILNTESPNLTYEAERLSMEKVEDAPFDPIDRIGQLTMRNLDVSDTRGKLGI  423

Query  425  YTNSGLLSIGHGSAVPQLETK  445
            Y  +GLLS    S +PQL  K
Sbjct  424  YAQTGLLSAIKDSVLPQLGKK  444


>A5UFF8 Argininosuccinate synthase [Haemophilus influenzae (strain 
PittGG)]
Length=444

 Score = 752 bits (1941),  Expect = 0.0
 Identities = 371/441 (84%), Positives = 403/441 (91%), Gaps = 1/441 (0%)

Query  6    TILQHVPVGKKVGIAFSGGLDTSAALLWMKQKGAEPYAYTANLGQPDEDDYDAIPKKAEQ  65
            TILQ++P G+KVGIAFSGGLDTSAALLWM+QKGA PYAYTANLGQPDEDDY+AIPKKA  
Sbjct  4    TILQNLPKGQKVGIAFSGGLDTSAALLWMRQKGAVPYAYTANLGQPDEDDYNAIPKKAMA  63

Query  66   YGAVKARLIDCRLQLALEGIAAIQCGAFHISTGGVPYFNTTPLGRAVTGTMLVTAMKEDD  125
            YGA  ARLIDCR QLA EGIAAIQCGAFHISTGG+PYFNTTPLGRAVTGTMLV AMKEDD
Sbjct  64   YGAENARLIDCRAQLAHEGIAAIQCGAFHISTGGIPYFNTTPLGRAVTGTMLVAAMKEDD  123

Query  126  VNIWGDGSTYKGNDIERFYRYGLLTNPNLKIYKPWLDQTFIDELGGRAEMSQFLIDNGFD  185
            VNIWGDGST+KGNDIERFYRYGLLTNPNLKIYKPWLD  FI+ELGGR EMSQFLI+NGFD
Sbjct  124  VNIWGDGSTFKGNDIERFYRYGLLTNPNLKIYKPWLDVQFIEELGGRLEMSQFLIENGFD  183

Query  186  YKMSKEKAYSTDSNMLGATHEAKDLEYLDAGIKIVDPIMGVAFWKDEVEIQPEQVSITFE  245
            YKMS EKAYSTDSNMLGATHEAKDLE L  G+KIV PIMGVAFW ++VEI+PE V++TFE
Sbjct  184  YKMSVEKAYSTDSNMLGATHEAKDLEQLSTGMKIVKPIMGVAFWDEKVEIKPETVTVTFE  243

Query  246  EGMPVALNGQRIEDPVEFILEANRIGGRHGLGMSDQIENRIIEAKSRGIYEAPGMALLHI  305
            +G+PVALNG+  ++ V+ ILEANRIGGRHGLGMSDQIENRIIEAKSRGIYEAPGMALLHI
Sbjct  244  DGVPVALNGKHFDNAVDLILEANRIGGRHGLGMSDQIENRIIEAKSRGIYEAPGMALLHI  303

Query  306  AYERLVTGIHNEDTIEQYRINGLRLGRLLYQGRWFDSQSLMLRETAQRWVAKAITGTVTL  365
            AYERLVTGIHNEDTIEQYRING+RLGRLLYQGRWFD Q+LMLRETAQRWVAKAITGTVTL
Sbjct  304  AYERLVTGIHNEDTIEQYRINGIRLGRLLYQGRWFDPQALMLRETAQRWVAKAITGTVTL  363

Query  366  ELRRGNDYTIMNTESPNLTYEAERLTMEK-GDSMFSPMDRIGQLTMRNLDITDTRAKLGI  424
            ELRRGND+TI+NTESPNLTYEAERL+MEK  D+ F P+DRIGQLTMRNLD++DTR KLGI
Sbjct  364  ELRRGNDFTILNTESPNLTYEAERLSMEKVEDAPFDPIDRIGQLTMRNLDVSDTRGKLGI  423

Query  425  YTNSGLLSIGHGSAVPQLETK  445
            Y  +GLLS    S +PQL  K
Sbjct  424  YAQTGLLSAIKDSVLPQLGKK  444


>A5UBF3 Argininosuccinate synthase [Haemophilus influenzae (strain 
PittEE)]
Length=444

 Score = 751 bits (1940),  Expect = 0.0
 Identities = 371/441 (84%), Positives = 403/441 (91%), Gaps = 1/441 (0%)

Query  6    TILQHVPVGKKVGIAFSGGLDTSAALLWMKQKGAEPYAYTANLGQPDEDDYDAIPKKAEQ  65
            TILQ++P G+KVGIAFSGGLDTSAALLWM+QKGA PYAYTANLGQPDEDDY+AIPKKA  
Sbjct  4    TILQNLPKGQKVGIAFSGGLDTSAALLWMRQKGAVPYAYTANLGQPDEDDYNAIPKKAMA  63

Query  66   YGAVKARLIDCRLQLALEGIAAIQCGAFHISTGGVPYFNTTPLGRAVTGTMLVTAMKEDD  125
            YGA  ARLIDCR QLA EGIAAIQCGAFHISTGG+PYFNTTPLGRAVTGTMLV AMKEDD
Sbjct  64   YGAENARLIDCRSQLAHEGIAAIQCGAFHISTGGIPYFNTTPLGRAVTGTMLVAAMKEDD  123

Query  126  VNIWGDGSTYKGNDIERFYRYGLLTNPNLKIYKPWLDQTFIDELGGRAEMSQFLIDNGFD  185
            VNIWGDGST+KGNDIERFYRYGLLTNPNLKIYKPWLD  FI+ELGGR EMSQFLI+NGFD
Sbjct  124  VNIWGDGSTFKGNDIERFYRYGLLTNPNLKIYKPWLDVQFIEELGGRLEMSQFLIENGFD  183

Query  186  YKMSKEKAYSTDSNMLGATHEAKDLEYLDAGIKIVDPIMGVAFWKDEVEIQPEQVSITFE  245
            YKMS EKAYSTDSNMLGATHEAKDLE L  G+KIV PIMGVAFW ++VEI+PE V++TFE
Sbjct  184  YKMSVEKAYSTDSNMLGATHEAKDLEQLSTGMKIVKPIMGVAFWDEKVEIKPETVTVTFE  243

Query  246  EGMPVALNGQRIEDPVEFILEANRIGGRHGLGMSDQIENRIIEAKSRGIYEAPGMALLHI  305
            +G+PVALNG+  ++ V+ ILEANRIGGRHGLGMSDQIENRIIEAKSRGIYEAPGMALLHI
Sbjct  244  DGVPVALNGKHFDNAVDLILEANRIGGRHGLGMSDQIENRIIEAKSRGIYEAPGMALLHI  303

Query  306  AYERLVTGIHNEDTIEQYRINGLRLGRLLYQGRWFDSQSLMLRETAQRWVAKAITGTVTL  365
            AYERLVTGIHNEDTIEQYRING+RLGRLLYQGRWFD Q+LMLRETAQRWVAKAITGTVTL
Sbjct  304  AYERLVTGIHNEDTIEQYRINGIRLGRLLYQGRWFDPQALMLRETAQRWVAKAITGTVTL  363

Query  366  ELRRGNDYTIMNTESPNLTYEAERLTMEK-GDSMFSPMDRIGQLTMRNLDITDTRAKLGI  424
            ELRRGND+TI+NTESPNLTYEAERL+MEK  D+ F P+DRIGQLTMRNLD++DTR KLGI
Sbjct  364  ELRRGNDFTILNTESPNLTYEAERLSMEKVEDAPFDPVDRIGQLTMRNLDVSDTRGKLGI  423

Query  425  YTNSGLLSIGHGSAVPQLETK  445
            Y  +GLLS    S +PQL  K
Sbjct  424  YAQTGLLSAIKDSVLPQLGKK  444


>Q4QJM0 Argininosuccinate synthase [Haemophilus influenzae (strain 
86-028NP)]
Length=444

 Score = 751 bits (1940),  Expect = 0.0
 Identities = 371/441 (84%), Positives = 403/441 (91%), Gaps = 1/441 (0%)

Query  6    TILQHVPVGKKVGIAFSGGLDTSAALLWMKQKGAEPYAYTANLGQPDEDDYDAIPKKAEQ  65
            TILQ++P G+KVGIAFSGGLDTSAALLWM+QKGA PYAYTANLGQPDEDDY+AIPKKA  
Sbjct  4    TILQNLPKGQKVGIAFSGGLDTSAALLWMRQKGAVPYAYTANLGQPDEDDYNAIPKKAMA  63

Query  66   YGAVKARLIDCRLQLALEGIAAIQCGAFHISTGGVPYFNTTPLGRAVTGTMLVTAMKEDD  125
            YGA  ARLIDCR QLA EGIAAIQCGAFHISTGG+PYFNTTPLGRAVTGTMLV AMKEDD
Sbjct  64   YGAENARLIDCRSQLAHEGIAAIQCGAFHISTGGIPYFNTTPLGRAVTGTMLVAAMKEDD  123

Query  126  VNIWGDGSTYKGNDIERFYRYGLLTNPNLKIYKPWLDQTFIDELGGRAEMSQFLIDNGFD  185
            VNIWGDGST+KGNDIERFYRYGLLTNPNLKIYKPWLD  FI+ELGGR EMSQFLI+NGFD
Sbjct  124  VNIWGDGSTFKGNDIERFYRYGLLTNPNLKIYKPWLDVQFIEELGGRLEMSQFLIENGFD  183

Query  186  YKMSKEKAYSTDSNMLGATHEAKDLEYLDAGIKIVDPIMGVAFWKDEVEIQPEQVSITFE  245
            YKMS EKAYSTDSNMLGATHEAKDLE L  G+KIV PIMGVAFW ++VEI+PE V++TFE
Sbjct  184  YKMSVEKAYSTDSNMLGATHEAKDLEQLSTGMKIVKPIMGVAFWDEKVEIKPETVTVTFE  243

Query  246  EGMPVALNGQRIEDPVEFILEANRIGGRHGLGMSDQIENRIIEAKSRGIYEAPGMALLHI  305
            +G+PVALNG+  ++ V+ ILEANRIGGRHGLGMSDQIENRIIEAKSRGIYEAPGMALLHI
Sbjct  244  DGVPVALNGKHFDNAVDLILEANRIGGRHGLGMSDQIENRIIEAKSRGIYEAPGMALLHI  303

Query  306  AYERLVTGIHNEDTIEQYRINGLRLGRLLYQGRWFDSQSLMLRETAQRWVAKAITGTVTL  365
            AYERLVTGIHNEDTIEQYRING+RLGRLLYQGRWFD Q+LMLRETAQRWVAKAITGTVTL
Sbjct  304  AYERLVTGIHNEDTIEQYRINGIRLGRLLYQGRWFDPQALMLRETAQRWVAKAITGTVTL  363

Query  366  ELRRGNDYTIMNTESPNLTYEAERLTMEK-GDSMFSPMDRIGQLTMRNLDITDTRAKLGI  424
            ELRRGND+TI+NTESPNLTYEAERL+MEK  D+ F P+DRIGQLTMRNLD++DTR KLGI
Sbjct  364  ELRRGNDFTILNTESPNLTYEAERLSMEKVEDAPFDPVDRIGQLTMRNLDVSDTRGKLGI  423

Query  425  YTNSGLLSIGHGSAVPQLETK  445
            Y  +GLLS    S +PQL  K
Sbjct  424  YAQTGLLSAIKDSVLPQLGKK  444


>B2UBA3 Argininosuccinate synthase [Ralstonia pickettii (strain 
12J)]
Length=445

 Score = 744 bits (1922),  Expect = 0.0
 Identities = 368/442 (83%), Positives = 401/442 (91%), Gaps = 1/442 (0%)

Query  6    TILQHVPVGKKVGIAFSGGLDTSAALLWMKQKGAEPYAYTANLGQPDEDDYDAIPKKAEQ  65
            TILQHVPVG+KVGIAFSGGLDTSAAL WMK KGA PYAYTANLGQPDE+DYDAIP+KA +
Sbjct  3    TILQHVPVGQKVGIAFSGGLDTSAALRWMKNKGALPYAYTANLGQPDEEDYDAIPRKAME  62

Query  66   YGAVKARLIDCRLQLALEGIAAIQCGAFHISTGGVPYFNTTPLGRAVTGTMLVTAMKEDD  125
            YGA KARLIDCR QLA EGIAAIQ GAFHISTGG+ YFNTTPLGRAVTGTMLV AMKEDD
Sbjct  63   YGAEKARLIDCRPQLANEGIAAIQSGAFHISTGGITYFNTTPLGRAVTGTMLVAAMKEDD  122

Query  126  VNIWGDGSTYKGNDIERFYRYGLLTNPNLKIYKPWLDQTFIDELGGRAEMSQFLIDNGFD  185
            VNIWGDGST+KGNDIERFYRYGLLTNP LKIYKPWLDQ FIDELGGRAEMS F+   GF 
Sbjct  123  VNIWGDGSTFKGNDIERFYRYGLLTNPALKIYKPWLDQAFIDELGGRAEMSAFMTKEGFG  182

Query  186  YKMSKEKAYSTDSNMLGATHEAKDLEYLDAGIKIVDPIMGVAFWKDEVEIQPEQVSITFE  245
            YKMS EKAYSTDSNMLGATHEAKDLE+L++GI+IV+PIMGVAFWK EVE++ E+VSITF+
Sbjct  183  YKMSAEKAYSTDSNMLGATHEAKDLEHLNSGIRIVNPIMGVAFWKPEVEVKAEEVSITFD  242

Query  246  EGMPVALNGQRIEDPVEFILEANRIGGRHGLGMSDQIENRIIEAKSRGIYEAPGMALLHI  305
            EG PVA+NG+ I DPVE  LE NRIGGRHGLGMSDQIENRIIEAKSRGIYEAPGMALLHI
Sbjct  243  EGRPVAVNGREIADPVEMFLELNRIGGRHGLGMSDQIENRIIEAKSRGIYEAPGMALLHI  302

Query  306  AYERLVTGIHNEDTIEQYRINGLRLGRLLYQGRWFDSQSLMLRETAQRWVAKAITGTVTL  365
            AYERLVTGIHNEDTIEQYRINGLRLGRLLYQGRWFD Q++MLRETAQRWVA+A+TGTVTL
Sbjct  303  AYERLVTGIHNEDTIEQYRINGLRLGRLLYQGRWFDPQAIMLRETAQRWVARAVTGTVTL  362

Query  366  ELRRGNDYTIMNTESPNLTYEAERLTMEK-GDSMFSPMDRIGQLTMRNLDITDTRAKLGI  424
            ELRRGNDY+I+NTESPNLTY  ERL+MEK  D+ FSP DRIGQLTMRNLD+ DTR KL I
Sbjct  363  ELRRGNDYSILNTESPNLTYAPERLSMEKVEDAPFSPADRIGQLTMRNLDLMDTRDKLAI  422

Query  425  YTNSGLLSIGHGSAVPQLETKK  446
            Y+ +GLLS+G  +A+PQL+  K
Sbjct  423  YSKAGLLSLGTANALPQLDGGK  444


>Q8XWC1 Argininosuccinate synthase [Ralstonia nicotianae (strain 
GMI1000)]
Length=445

 Score = 744 bits (1922),  Expect = 0.0
 Identities = 368/438 (84%), Positives = 400/438 (91%), Gaps = 1/438 (0%)

Query  6    TILQHVPVGKKVGIAFSGGLDTSAALLWMKQKGAEPYAYTANLGQPDEDDYDAIPKKAEQ  65
            TILQHVPVG+KVGIAFSGGLDTSAAL WMK KGA PYAYTANLGQPDE+DYDAIP+KA +
Sbjct  3    TILQHVPVGQKVGIAFSGGLDTSAALRWMKNKGALPYAYTANLGQPDEEDYDAIPRKALE  62

Query  66   YGAVKARLIDCRLQLALEGIAAIQCGAFHISTGGVPYFNTTPLGRAVTGTMLVTAMKEDD  125
            YGA KARLIDCR QLA EGIAAIQ GAFHISTGG+ YFNTTPLGRAVTGTMLV AMKEDD
Sbjct  63   YGAEKARLIDCRPQLANEGIAAIQAGAFHISTGGITYFNTTPLGRAVTGTMLVAAMKEDD  122

Query  126  VNIWGDGSTYKGNDIERFYRYGLLTNPNLKIYKPWLDQTFIDELGGRAEMSQFLIDNGFD  185
            V+IWGDGST+KGNDIERFYRYGLLTNP LKIYKPWLDQTFIDELGGRAEMS F+   GF 
Sbjct  123  VHIWGDGSTFKGNDIERFYRYGLLTNPALKIYKPWLDQTFIDELGGRAEMSAFMTKEGFG  182

Query  186  YKMSKEKAYSTDSNMLGATHEAKDLEYLDAGIKIVDPIMGVAFWKDEVEIQPEQVSITFE  245
            YKMS EKAYSTDSNMLGATHEAKDLE+L++GI+IV+PIMGVAFWK EVE++ E+VSITF+
Sbjct  183  YKMSAEKAYSTDSNMLGATHEAKDLEHLNSGIRIVNPIMGVAFWKPEVEVKAEEVSITFD  242

Query  246  EGMPVALNGQRIEDPVEFILEANRIGGRHGLGMSDQIENRIIEAKSRGIYEAPGMALLHI  305
            EG PVA+NG+ I DPVE  LE NRIGGRHGLGMSDQIENRIIEAKSRGIYEAPGMALLHI
Sbjct  243  EGRPVAVNGREIADPVEMFLELNRIGGRHGLGMSDQIENRIIEAKSRGIYEAPGMALLHI  302

Query  306  AYERLVTGIHNEDTIEQYRINGLRLGRLLYQGRWFDSQSLMLRETAQRWVAKAITGTVTL  365
            AYERLVTGIHNEDTIEQYRINGLRLGRLLYQGRWFD Q++MLRETAQRWVA+A+TGTVTL
Sbjct  303  AYERLVTGIHNEDTIEQYRINGLRLGRLLYQGRWFDPQAIMLRETAQRWVARAVTGTVTL  362

Query  366  ELRRGNDYTIMNTESPNLTYEAERLTMEK-GDSMFSPMDRIGQLTMRNLDITDTRAKLGI  424
            ELRRGNDY+I+NTESPNLTY  ERL+MEK  D+ FSP DRIGQLTMRNLD+ DTR KL I
Sbjct  363  ELRRGNDYSILNTESPNLTYAPERLSMEKVEDAPFSPADRIGQLTMRNLDLMDTRDKLAI  422

Query  425  YTNSGLLSIGHGSAVPQL  442
            Y+ +GLLS+G  SA+PQL
Sbjct  423  YSKAGLLSLGTSSALPQL  440


>P0A6E4 Argininosuccinate synthase [Escherichia coli (strain K12)]
Length=447

 Score = 705 bits (1820),  Expect = 0.0
 Identities = 346/438 (79%), Positives = 385/438 (88%), Gaps = 0/438 (0%)

Query  6    TILQHVPVGKKVGIAFSGGLDTSAALLWMKQKGAEPYAYTANLGQPDEDDYDAIPKKAEQ  65
            TIL+H+PVG+++GIAFSGGLDTSAALLWM+QKGA PYAYTANLGQPDE+DYDAIP++A +
Sbjct  3    TILKHLPVGQRIGIAFSGGLDTSAALLWMRQKGAVPYAYTANLGQPDEEDYDAIPRRAME  62

Query  66   YGAVKARLIDCRLQLALEGIAAIQCGAFHISTGGVPYFNTTPLGRAVTGTMLVTAMKEDD  125
            YGA  ARLIDCR QL  EGIAAIQCGAFH +TGG+ YFNTTPLGRAVTGTMLV AMKED 
Sbjct  63   YGAENARLIDCRKQLVAEGIAAIQCGAFHNTTGGLTYFNTTPLGRAVTGTMLVAAMKEDG  122

Query  126  VNIWGDGSTYKGNDIERFYRYGLLTNPNLKIYKPWLDQTFIDELGGRAEMSQFLIDNGFD  185
            VNIWGDGSTYKGNDIERFYRYGLLTN  L+IYKPWLD  FIDELGGR EMS+F+I  GFD
Sbjct  123  VNIWGDGSTYKGNDIERFYRYGLLTNAELQIYKPWLDTDFIDELGGRHEMSEFMIACGFD  182

Query  186  YKMSKEKAYSTDSNMLGATHEAKDLEYLDAGIKIVDPIMGVAFWKDEVEIQPEQVSITFE  245
            YKMS EKAYSTDSNMLGATHEAKDLEYL++ +KIV+PIMGV FW + V+I  E+V++ FE
Sbjct  183  YKMSVEKAYSTDSNMLGATHEAKDLEYLNSSVKIVNPIMGVKFWDESVKIPAEEVTVRFE  242

Query  246  EGMPVALNGQRIEDPVEFILEANRIGGRHGLGMSDQIENRIIEAKSRGIYEAPGMALLHI  305
            +G PVALNG+   D VE +LEANRIGGRHGLGMSDQIENRIIEAKSRGIYEAPGMALLHI
Sbjct  243  QGHPVALNGKTFSDDVEMMLEANRIGGRHGLGMSDQIENRIIEAKSRGIYEAPGMALLHI  302

Query  306  AYERLVTGIHNEDTIEQYRINGLRLGRLLYQGRWFDSQSLMLRETAQRWVAKAITGTVTL  365
            AYERL+TGIHNEDTIEQY  +G +LGRLLYQGRWFDSQ+LMLR++ QRWVA  ITG VTL
Sbjct  303  AYERLLTGIHNEDTIEQYHAHGRQLGRLLYQGRWFDSQALMLRDSLQRWVASQITGEVTL  362

Query  366  ELRRGNDYTIMNTESPNLTYEAERLTMEKGDSMFSPMDRIGQLTMRNLDITDTRAKLGIY  425
            ELRRGNDY+I+NT S NLTY+ ERLTMEKGDS+FSP DRIGQLTMRNLDITDTR KL  Y
Sbjct  363  ELRRGNDYSILNTVSENLTYKPERLTMEKGDSVFSPDDRIGQLTMRNLDITDTREKLFGY  422

Query  426  TNSGLLSIGHGSAVPQLE  443
              +GLLS    S VPQ+E
Sbjct  423  AKTGLLSSSAASGVPQVE  440


>P0C1A1 Argininosuccinate synthase [Dickeya dadantii (strain 3937)]
Length=449

 Score = 700 bits (1806),  Expect = 0.0
 Identities = 343/437 (78%), Positives = 382/437 (87%), Gaps = 1/437 (0%)

Query  6    TILQHVPVGKKVGIAFSGGLDTSAALLWMKQKGAEPYAYTANLGQPDEDDYDAIPKKAEQ  65
            TIL+H+PVG+++GIAFSGGLDTSAALLWM+QKGA PYAYTANLGQPDEDDYDAIP++A++
Sbjct  3    TILKHLPVGQRIGIAFSGGLDTSAALLWMRQKGAVPYAYTANLGQPDEDDYDAIPRRAKE  62

Query  66   YGAVKARLIDCRLQLALEGIAAIQCGAFHISTGGVPYFNTTPLGRAVTGTMLVTAMKEDD  125
            YGA  ARLIDCR QL  EGIAAIQCGAFH +TGG+ YFNTTPLGRAVTGTMLV AMKED 
Sbjct  63   YGAENARLIDCRKQLVAEGIAAIQCGAFHNTTGGMTYFNTTPLGRAVTGTMLVAAMKEDG  122

Query  126  VNIWGDGSTYKGNDIERFYRYGLLTNPNLKIYKPWLDQTFIDELGGRAEMSQFLIDNGFD  185
            VNIWGDGSTYKGNDIERFYRYGLLTN  LKIYKPWLD  FIDELGGR EMS+F+  +GFD
Sbjct  123  VNIWGDGSTYKGNDIERFYRYGLLTNAELKIYKPWLDTDFIDELGGRQEMSEFMTTSGFD  182

Query  186  YKMSKEKAYSTDSNMLGATHEAKDLEYLDAGIKIVDPIMGVAFWKDEVEIQPEQVSITFE  245
            YKMS EKAYSTDSNMLGATHEAKDLE+L++ +KIV+PIMGV FW + V I  E+V++ FE
Sbjct  183  YKMSAEKAYSTDSNMLGATHEAKDLEFLNSSVKIVNPIMGVKFWDENVRIPAEEVTVRFE  242

Query  246  EGMPVALNGQRIEDPVEFILEANRIGGRHGLGMSDQIENRIIEAKSRGIYEAPGMALLHI  305
             G PVALNGQ   D VE +LEANRIGGRHGLGMSDQIENRIIEAKSRGIYEAPGMALLHI
Sbjct  243  RGHPVALNGQTFSDDVELLLEANRIGGRHGLGMSDQIENRIIEAKSRGIYEAPGMALLHI  302

Query  306  AYERLVTGIHNEDTIEQYRINGLRLGRLLYQGRWFDSQSLMLRETAQRWVAKAITGTVTL  365
            AYERLVTGIHNEDTIEQY  +G +LGRLLYQGRWFD Q+LMLR+  QRWVA  ITG VTL
Sbjct  303  AYERLVTGIHNEDTIEQYHAHGRQLGRLLYQGRWFDPQALMLRDALQRWVASEITGEVTL  362

Query  366  ELRRGNDYTIMNTESPNLTYEAERLTMEKGDSMFSPMDRIGQLTMRNLDITDTRAKLGIY  425
            ELRRGNDY+I+NT S NLTY+ ERLTMEKG+S+FSP DRIGQLTMRNLDITDTR KL  Y
Sbjct  363  ELRRGNDYSILNTVSDNLTYKPERLTMEKGESVFSPDDRIGQLTMRNLDITDTREKLFNY  422

Query  426  TNSGLLSIGHGSAVPQL  442
              SGL+  G+ + +PQ+
Sbjct  423  VESGLIFSGN-AGLPQV  438


>Q06734 Argininosuccinate synthase [Streptomyces lavendulae]
Length=482

 Score = 577 bits (1486),  Expect = 0.0
 Identities = 277/434 (64%), Positives = 336/434 (77%), Gaps = 1/434 (0%)

Query  7    ILQHVPVGKKVGIAFSGGLDTSAALLWMKQKGAEPYAYTANLGQPDEDDYDAIPKKAEQY  66
            +L  +P G++VGIAFSGGLDTS A+ WM+ KGA P  YTA++GQ DE D  ++P +A  Y
Sbjct  4    VLTSLPAGERVGIAFSGGLDTSVAVAWMRDKGAVPCTYTADIGQYDEPDIASVPSRASAY  63

Query  67   GAVKARLIDCRLQLALEGIAAIQCGAFHISTGGVPYFNTTPLGRAVTGTMLVTAMKEDDV  126
            GA   RL+DCR  L  EG+AA+ CGAFHI +GG PYFNTTPLGRAVTGT+LV AM ED V
Sbjct  64   GAEITRLVDCRAALVEEGLAALACGAFHIRSGGRPYFNTTPLGRAVTGTLLVRAMLEDGV  123

Query  127  NIWGDGSTYKGNDIERFYRYGLLTNPNLKIYKPWLDQTFIDELGGRAEMSQFLIDNGFDY  186
             IWGDGST+KGNDIERFYRYGLL NP+L+IYKPWLD  F+ ELGGR EMS++L+ +G  Y
Sbjct  124  QIWGDGSTFKGNDIERFYRYGLLANPHLRIYKPWLDADFVTELGGRKEMSEWLLAHGLPY  183

Query  187  KMSKEKAYSTDSNMLGATHEAKDLEYLDAGIKIVDPIMGVAFWKDEVEIQPEQVSITFEE  246
            + S EKAYSTD+N+ GATHEAK LE+LD GI+ VDPIMGV FW   VEI  E V++ FE+
Sbjct  184  RDSTEKAYSTDANIWGATHEAKTLEHLDTGIETVDPIMGVRFWDPSVEIATEDVTVGFEQ  243

Query  247  GMPVALNGQRIEDPVEFILEANRIGGRHGLGMSDQIENRIIEAKSRGIYEAPGMALLHIA  306
            G PV++NG+     V+ ++EAN IGGRHGLGMSDQIENRIIEAKSRGIYEAPGMALLHI 
Sbjct  244  GRPVSINGKEFASAVDLVMEANAIGGRHGLGMSDQIENRIIEAKSRGIYEAPGMALLHIV  303

Query  307  YERLVTGIHNEDTIEQYRINGLRLGRLLYQGRWFDSQSLMLRETAQRWVAKAITGTVTLE  366
            YERLV  IHNEDT+  Y   G RLGRL+Y+GRW D Q+LM+RE+ QRWV  A+TG VTL 
Sbjct  304  YERLVNAIHNEDTLAAYHNEGRRLGRLMYEGRWLDPQALMIRESLQRWVGTAVTGEVTLR  363

Query  367  LRRGNDYTIMNTESPNLTYEAERLTMEK-GDSMFSPMDRIGQLTMRNLDITDTRAKLGIY  425
            LRRG DY+I++T  P  +Y  ++L+ME+  DS F P+DRIGQLTMRNLDI D+RA+L  Y
Sbjct  364  LRRGEDYSILDTTGPAFSYHPDKLSMERTEDSAFGPVDRIGQLTMRNLDIADSRARLEQY  423

Query  426  TNSGLLSIGHGSAV  439
               GL+   H + +
Sbjct  424  VGLGLVGTPHPTPI  437


>P59846 Argininosuccinate synthase [Thermus thermophilus (strain 
ATCC 27634 / DSM 579 / HB8)]
Length=400

 Score = 172 bits (436),  Expect = 3e-52
 Identities = 119/384 (31%), Positives = 198/384 (52%), Gaps = 23/384 (6%)

Query  16   KVGIAFSGGLDTSAALLWMKQK-GAEPYAYTANLGQPDEDDYDAIPKKAEQYGAVKARLI  74
            K+ +A+SGGLDTS  L W+K+   AE  A+TA++GQ +E   +   +KA + GA KA  +
Sbjct  2    KIVLAYSGGLDTSIILKWLKETYRAEVIAFTADIGQGEE--VEEAREKALRTGASKAIAL  59

Query  75   DCRLQLALEGI-AAIQCGAFHISTGGVPYFNTTPLGRAVTGTMLVTAMKEDDVNIWGDGS  133
            D + +   + +   ++ GA +       Y   T + R +    LV   +E+       G+
Sbjct  60   DLKEEFVRDFVFPMMRAGAVYEGY----YLLGTSIARPLIAKHLVRIAEEEGAEAIAHGA  115

Query  134  TYKGNDIERFYRYGLLTNPNLKIYKPWLDQTFIDELGGRAEMSQFLIDNGFDYKMSKEKA  193
            T KGND  RF        P++K+  PW + +F     GR EM  +   +G    +++EK 
Sbjct  116  TGKGNDQVRFELTAYALKPDIKVIAPWREWSF----QGRKEMIAYAEAHGIPVPVTQEKP  171

Query  194  YSTDSNMLGATHEAKDLEYLDAGIKIVDPIMGVAFWKDEVEIQPEQVSITFEEGMPVALN  253
            YS D+N+L  ++E   LE  D   +    +  +    +E    PE V + F EG PVA+N
Sbjct  172  YSMDANLLHISYEGGVLE--DPWAEPPKGMFRMTQDPEEAPDAPEYVEVEFFEGDPVAVN  229

Query  254  GQRIEDPVEFILEANRIGGRHGLGMSDQIENRIIEAKSRGIYEAPGMALLHIAYERLVTG  313
            G+R+  P   +   N IGGRHG+G  D +ENR +  KSRG+YE PG  +L+ A   + + 
Sbjct  230  GERLS-PAALLQRLNEIGGRHGVGRVDIVENRFVGMKSRGVYETPGGTILYHARRAVESL  288

Query  314  IHNEDTIEQYRINGLRLGRLLYQGRWFDSQSLMLRETAQRW---VAKAITGTVTLELRRG  370
              + + + Q  +   +   L+Y G W+  +    RE  Q +   VA+++TG   L+L +G
Sbjct  289  TLDREVLHQRDMLSPKYAELVYYGFWYAPE----REALQAYFDHVARSVTGVARLKLYKG  344

Query  371  NDYTIMNTESPNLTYEAERLTMEK  394
            N Y ++  ++P   Y  + ++ ++
Sbjct  345  NVY-VVGRKAPKSLYRQDLVSFDE  367


>Q93JQ8 Argininosuccinate synthase [Rhodococcus fascians]
Length=395

 Score = 159 bits (401),  Expect = 3e-47
 Identities = 121/381 (32%), Positives = 185/381 (49%), Gaps = 16/381 (4%)

Query  19   IAFSGGLDTSAALLWMKQK-GAEPYAYTANLGQPDEDDYDAIPKKAEQYGAVKARLIDCR  77
            +A+SGGLDTS A+ W+K++   E  AY ANLGQ +  D +A+ K+A   GA +  + D R
Sbjct  5    LAYSGGLDTSVAVHWLKERYQTEVIAYCANLGQIE--DLEAVSKRATAAGASEVIVEDVR  62

Query  78   -LQLALEGIAAIQCGAFHISTGGVPYFNTTPLGRAVTGTMLVTAMKEDDVNIWGDGSTYK  136
             L L    I A+  GA +       Y    PL R +    LV+  +E   +    G+T K
Sbjct  63   DLFLHDYAIPALAAGAAYEGK----YLLAAPLSRPLIAERLVSIARERGASAVAHGATGK  118

Query  137  GNDIERFYRYGLLTNPNLKIYKPWLDQTFIDELGGRAEMSQFLIDNGFDYKMSKEKAYST  196
            GND  RFY       P L I  P +D     E+  R     +   +G D  +SK   YS 
Sbjct  119  GNDQVRFYTSVRALAPELDILAPVIDW----EMTSRGSEIAYADRHGIDVGVSKTTPYSI  174

Query  197  DSNMLGATHEAKDLEYLDAGIKIVDPIMGVAFWKDEVEIQPEQVSITFEEGMPVALNGQR  256
            D+N+ G + E  DL+ +D           +     +   +P  ++I FE G+PVAL+G++
Sbjct  175  DTNIWGTSIECGDLDLIDHAPP--PDAWQITTAPVQAPDRPTTITIEFEAGIPVALDGRK  232

Query  257  IEDPVEFILEANRIGGRHGLGMSDQIENRIIEAKSRGIYEAPGMALLHIAYERLVTGIHN  316
            + D ++ + E       +G+G ++ +E+RI+  KSRGIYEAP   +L  A   L   + +
Sbjct  233  L-DLIDLVSELGDTAAANGIGRTEILESRIVGFKSRGIYEAPAATVLLAARTDLEALVLD  291

Query  317  EDTIEQYRINGLRLGRLLYQGRWFDSQSLMLRETAQRWVAKAITGTVTLELRRGNDYTIM  376
             +T+   R    +   L+Y G WF      L     R +A  +TGTVT+EL +G+   I 
Sbjct  292  RETLHHKRSIADQYAELVYYGYWFTDLRAALDAYCAR-LAHRVTGTVTVELYKGSARCIG  350

Query  377  NTESPNLTYEAERLTMEKGDS  397
             T      Y +     E+ D+
Sbjct  351  RTSPKYGRYSSALADYEEADT  371


>P16460 Argininosuccinate synthase [Mus musculus]
Length=412

 Score = 155 bits (392),  Expect = 7e-46
 Identities = 117/413 (28%), Positives = 197/413 (48%), Gaps = 30/413 (7%)

Query  17   VGIAFSGGLDTSAALLWMKQKGAEPYAYTANLGQPDEDDYDAIPKKAEQYGAVKARLIDC  76
            V +A+SGGLDTS  L+W+K++G +  AY AN+GQ  ++D++   KKA + GA K  + D 
Sbjct  7    VVLAYSGGLDTSCILVWLKEQGYDVIAYLANIGQ--KEDFEEARKKALKLGAKKVFIEDV  64

Query  77   RLQLALEGI-AAIQCGAFHISTGGVPYFNTTPLGRAVTGTMLVTAMKEDDVNIWGDGSTY  135
              +   E I  A+Q  A +       Y   T L R       V   + +       G+T 
Sbjct  65   SKEFVEEFIWPAVQSSALYEDR----YLLGTSLARPCIARRQVEIAQREGAKYVSHGATG  120

Query  136  KGNDIERFYRYGLLTNPNLKIYKPWLDQTFIDELGGRAEMSQFLIDNGFDYKMSKEKAYS  195
            KGND  RF        P +K+  PW    F +   GR ++ ++   +G    ++ +  +S
Sbjct  121  KGNDQVRFELTCYSLAPQIKVIAPWRMPEFYNRFKGRNDLMEYAKQHGIPIPVTPKSPWS  180

Query  196  TDSNMLGATHEAKDLE----YLDAGI--KIVDPIMGVAFWKDEVEIQPEQVSITFEEGMP  249
             D N++  ++EA  LE        G+  K  DP         +    P+ + I F++G+P
Sbjct  181  MDENLMHISYEAGILENPKNQAPPGLYTKTQDPA--------KAPNSPDVLEIEFKKGVP  232

Query  250  VAL----NGQRIEDPVEFILEANRIGGRHGLGMSDQIENRIIEAKSRGIYEAPGMALLHI  305
            V +    +G      +E  +  N + G+HG+G  D +ENR I  KSRGIYE P   +L+ 
Sbjct  233  VKVTNIKDGTTRTTSLELFMYLNEVAGKHGVGRIDIVENRFIGMKSRGIYETPAGTILYH  292

Query  306  AYERLVTGIHNEDTIEQYRINGLRLGRLLYQGRWFDSQSLMLRETAQRWVAKAITGTVTL  365
            A+  +     + +  +  +  GL+   L+Y G W   +   +R   Q+   + + G V +
Sbjct  293  AHLDIEAFTMDREVRKIKQGLGLKFAELVYTGFWHSPECEFVRHCIQK-SQERVEGKVQV  351

Query  366  ELRRGNDYTIMNTESPNLTYEAERLTME-KGDSMFSPMDRIGQLTMRNLDITD  417
             + +G  Y I+  ESP   Y  E ++M  +GD  + P+D  G + + +L + +
Sbjct  352  SVFKGQVY-ILGRESPLSLYNEELVSMNVQGD--YEPIDATGFININSLRLKE  401


>P14568 Argininosuccinate synthase [Bos taurus]
Length=412

 Score = 155 bits (391),  Expect = 1e-45
 Identities = 118/413 (29%), Positives = 196/413 (47%), Gaps = 30/413 (7%)

Query  17   VGIAFSGGLDTSAALLWMKQKGAEPYAYTANLGQPDEDDYDAIPKKAEQYGAVKARLIDC  76
            V +A+SGGLDTS  L+W+K++G +  AY AN+GQ  ++D++   KKA + GA K  + D 
Sbjct  7    VVLAYSGGLDTSCILVWLKEQGYDVIAYLANIGQ--KEDFEEARKKALKLGAKKVFIEDI  64

Query  77   RLQLALEGI-AAIQCGAFHISTGGVPYFNTTPLGRAVTGTMLVTAMKEDDVNIWGDGSTY  135
              +   E I  AIQ  A +       Y   T L R       V   + +       G+T 
Sbjct  65   SKEFVEEFIWPAIQSSALYEDR----YLLGTSLARPCIARKQVEIAQREGAKYVSHGATG  120

Query  136  KGNDIERFYRYGLLTNPNLKIYKPWLDQTFIDELGGRAEMSQFLIDNGFDYKMSKEKAYS  195
            KGND  RF        P +K+  PW    F +   GR ++ ++   +G    ++ +  +S
Sbjct  121  KGNDQIRFELTCYSLAPQIKVIAPWRMPEFYNRFQGRNDLMEYAKQHGIPVPVTPKNPWS  180

Query  196  TDSNMLGATHEAKDLE----YLDAGI--KIVDPIMGVAFWKDEVEIQPEQVSITFEEGMP  249
             D N++  ++EA  LE        G+  K  DP         +    P+ + I F++G+P
Sbjct  181  MDENLMHISYEAGILENPKNQAPPGLYTKTQDPA--------KAPNSPDMLEIEFKKGVP  232

Query  250  VAL----NGQRIEDPVEFILEANRIGGRHGLGMSDQIENRIIEAKSRGIYEAPGMALLHI  305
            V +    +G      +E  L  N + G+HG+G  D +ENR I  KSRGIYE P   +L+ 
Sbjct  233  VKVTNVGDGTTHSTALELFLYLNEVAGKHGVGRIDIVENRFIGMKSRGIYETPAGTILYH  292

Query  306  AYERLVTGIHNEDTIEQYRINGLRLGRLLYQGRWFDSQSLMLRETAQRWVAKAITGTVTL  365
            A+  +     + +  +  +  GL+   L+Y G W   +   +R    +   + + G V +
Sbjct  293  AHLDIEAFTMDREVRKIKQGLGLKFAELVYTGFWHSPECEFVRHCIAK-SQERVEGKVQV  351

Query  366  ELRRGNDYTIMNTESPNLTYEAERLTME-KGDSMFSPMDRIGQLTMRNLDITD  417
             + +G  Y I+  ESP   Y  E ++M  +GD  + P+D  G + + +L + +
Sbjct  352  SVFKGQVY-ILGRESPLSLYNEELVSMNVQGD--YEPVDATGFININSLRLKE  401


>P22768 Argininosuccinate synthase [Saccharomyces cerevisiae (strain 
ATCC 204508 / S288c)]
Length=420

 Score = 155 bits (391),  Expect = 1e-45
 Identities = 121/417 (29%), Positives = 190/417 (46%), Gaps = 34/417 (8%)

Query  16   KVGIAFSGGLDTSAALLWMKQKGAEPYAYTANLGQPDEDDYDAIPKKAEQYGAVKARLID  75
            KV +A+SGGLDTS  L W+  +G E  A+ AN+GQ  E+D+DA  +KA + GA K   +D
Sbjct  5    KVCLAYSGGLDTSVILAWLLDQGYEVVAFMANVGQ--EEDFDAAKEKALKIGACKFVCVD  62

Query  76   CRLQLALEGI-AAIQCGAFHISTGGVPYFNTTPLGRAVTGTMLVTAMKEDDVNIWGDGST  134
            CR     + +  A+Q  A +       Y   T L R V     +   K++       G T
Sbjct  63   CREDFVKDILFPAVQVNAVYEDV----YLLGTSLARPVIAKAQIDVAKQEGCFAVSHGCT  118

Query  135  YKGNDIERFYRYGLLTNPNLKIYKPWLDQTFIDELGGRAEMSQFLIDNGFDYKMSKEKAY  194
             KGND  RF        P++K   PW    F +   GR ++  +    G     +K K +
Sbjct  119  GKGNDQIRFELSFYALKPDVKCITPWRMPEFFERFAGRKDLLDYAAQKGIPVAQTKAKPW  178

Query  195  STDSNMLGATHEAKDLEYLDAGIK------IVDPIMGVAFWKDEVEIQPEQVSITFEEGM  248
            STD N    ++EA  LE  D          IVDP+        +   QP+ ++I FE G+
Sbjct  179  STDENQAHISYEAGILEDPDTTPPKDMWKLIVDPM--------DAPDQPQDLTIDFERGL  230

Query  249  PVAL--------NGQRIEDPVEFILEANRIGGRHGLGMSDQIENRIIEAKSRGIYEAPGM  300
            PV L            +  P++  L A+ +   +G+G  D +E+R I  KSRG YE   +
Sbjct  231  PVKLTYTDNKTSKEVSVTKPLDVFLAASNLARANGVGRIDIVEDRYINLKSRGCYEQAPL  290

Query  301  ALLHIAYERLVTGIHNEDTIEQYRINGL--RLGRLLYQGRWFDSQSLMLRETAQRWVAKA  358
             +L  A+  L  G+  +  + Q R + +     RL+Y G +F  +   +R   Q     +
Sbjct  291  TVLRKAHVDL-EGLTLDKEVRQLRDSFVTPNYSRLIYNGSYFTPECEYIRSMIQP-SQNS  348

Query  359  ITGTVTLELRRGNDYTIMNTESPNLTYEAERLTMEKGDSMFSPMDRIGQLTMRNLDI  415
            + GTV + L +GN   +  +      Y+    +M++    F P D  G + ++ + I
Sbjct  349  VNGTVRVRLYKGNVIILGRSTKTEKLYDPTESSMDELTG-FLPTDTTGFIAIQAIRI  404


>P00966 Argininosuccinate synthase [Homo sapiens]
Length=412

 Score = 153 bits (387),  Expect = 4e-45
 Identities = 117/413 (28%), Positives = 196/413 (47%), Gaps = 30/413 (7%)

Query  17   VGIAFSGGLDTSAALLWMKQKGAEPYAYTANLGQPDEDDYDAIPKKAEQYGAVKARLIDC  76
            V +A+SGGLDTS  L+W+K++G +  AY AN+GQ  ++D++   KKA + GA K  + D 
Sbjct  7    VVLAYSGGLDTSCILVWLKEQGYDVIAYLANIGQ--KEDFEEARKKALKLGAKKVFIEDV  64

Query  77   RLQLALEGI-AAIQCGAFHISTGGVPYFNTTPLGRAVTGTMLVTAMKEDDVNIWGDGSTY  135
              +   E I  AIQ  A +       Y   T L R       V   + +       G+T 
Sbjct  65   SREFVEEFIWPAIQSSALYEDR----YLLGTSLARPCIARKQVEIAQREGAKYVSHGATG  120

Query  136  KGNDIERFYRYGLLTNPNLKIYKPWLDQTFIDELGGRAEMSQFLIDNGFDYKMSKEKAYS  195
            KGND  RF        P +K+  PW    F +   GR ++ ++   +G    ++ +  +S
Sbjct  121  KGNDQVRFELSCYSLAPQIKVIAPWRMPEFYNRFKGRNDLMEYAKQHGIPIPVTPKNPWS  180

Query  196  TDSNMLGATHEAKDLE----YLDAGI--KIVDPIMGVAFWKDEVEIQPEQVSITFEEGMP  249
             D N++  ++EA  LE        G+  K  DP         +    P+ + I F++G+P
Sbjct  181  MDENLMHISYEAGILENPKNQAPPGLYTKTQDPA--------KAPNTPDILEIEFKKGVP  232

Query  250  VAL----NGQRIEDPVEFILEANRIGGRHGLGMSDQIENRIIEAKSRGIYEAPGMALLHI  305
            V +    +G   +  +E  +  N + G+HG+G  D +ENR I  KSRGIYE P   +L+ 
Sbjct  233  VKVTNVKDGTTHQTSLELFMYLNEVAGKHGVGRIDIVENRFIGMKSRGIYETPAGTILYH  292

Query  306  AYERLVTGIHNEDTIEQYRINGLRLGRLLYQGRWFDSQSLMLRETAQRWVAKAITGTVTL  365
            A+  +     + +  +  +  GL+   L+Y G W   +   +R    +   + + G V +
Sbjct  293  AHLDIEAFTMDREVRKIKQGLGLKFAELVYTGFWHSPECEFVRHCIAK-SQERVEGKVQV  351

Query  366  ELRRGNDYTIMNTESPNLTYEAERLTME-KGDSMFSPMDRIGQLTMRNLDITD  417
             + +G  Y I+  ESP   Y  E ++M  +GD  + P D  G + + +L + +
Sbjct  352  SVLKGQVY-ILGRESPLSLYNEELVSMNVQGD--YEPTDATGFININSLRLKE  401


>P09034 Argininosuccinate synthase [Rattus norvegicus]
Length=412

 Score = 152 bits (384),  Expect = 1e-44
 Identities = 115/413 (28%), Positives = 196/413 (47%), Gaps = 30/413 (7%)

Query  17   VGIAFSGGLDTSAALLWMKQKGAEPYAYTANLGQPDEDDYDAIPKKAEQYGAVKARLIDC  76
            V +A+SGGLDTS  L+W+K++G +  AY AN+GQ  ++D++   KKA + GA K  + D 
Sbjct  7    VVLAYSGGLDTSCILVWLKEQGYDVIAYLANIGQ--KEDFEEARKKALKLGAKKVFIEDV  64

Query  77   RLQLALEGI-AAIQCGAFHISTGGVPYFNTTPLGRAVTGTMLVTAMKEDDVNIWGDGSTY  135
              +   E I  A+Q  A +       Y   T L R       V   + +       G+T 
Sbjct  65   SKEFVEEFIWPAVQSSALYEDR----YLLGTSLARPCIARKQVEIAQREGAKYVSHGATG  120

Query  136  KGNDIERFYRYGLLTNPNLKIYKPWLDQTFIDELGGRAEMSQFLIDNGFDYKMSKEKAYS  195
            KGND  RF        P +K+  PW    F +   GR ++ ++   +G    ++ +  +S
Sbjct  121  KGNDQVRFELTCYSLAPQIKVIAPWRMPEFYNRFKGRNDLMEYAKQHGIPIPVTPKSPWS  180

Query  196  TDSNMLGATHEAKDLE----YLDAGI--KIVDPIMGVAFWKDEVEIQPEQVSITFEEGMP  249
             D N++  ++EA  LE        G+  K  DP         +    P+ + I F++G+P
Sbjct  181  MDENLMHISYEAGILENPKNQAPPGLYTKTQDPA--------KAPNTPDVLEIEFKKGVP  232

Query  250  VAL----NGQRIEDPVEFILEANRIGGRHGLGMSDQIENRIIEAKSRGIYEAPGMALLHI  305
            V +    +G      ++  +  N + G+HG+G  D +ENR I  KSRGIYE P   +L+ 
Sbjct  233  VKVTNVKDGTTHSTSLDLFMYLNEVAGKHGVGRIDIVENRFIGMKSRGIYETPAGTILYH  292

Query  306  AYERLVTGIHNEDTIEQYRINGLRLGRLLYQGRWFDSQSLMLRETAQRWVAKAITGTVTL  365
            A+  +     + +  +  +  GL+   L+Y G W   +   +R    +   + + G V +
Sbjct  293  AHLDIEAFTMDREVRKIKQGLGLKFAELVYTGFWHSPECEFVRHCIDK-SQERVEGKVQV  351

Query  366  ELRRGNDYTIMNTESPNLTYEAERLTME-KGDSMFSPMDRIGQLTMRNLDITD  417
             + +G  Y I+  ESP   Y  E ++M  +GD  + P+D  G + + +L + +
Sbjct  352  SVFKGQVY-ILGRESPLSLYNEELVSMNVQGD--YEPIDATGFININSLRLKE  401



Lambda      K        H        a         alpha
   0.319    0.137    0.403    0.792     4.96 

Gapped
Lambda      K        H        a         alpha    sigma
   0.267   0.0410    0.140     1.90     42.6     43.6 

Effective search space used: 3456042


  Database: e65442465cec5c930b4369f7327ba964.SwissProt.fasta
    Posted date:  May 19, 2024  7:27 PM
  Number of letters in database: 10,036
  Number of sequences in database:  23



Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Neighboring words threshold: 11
Window for multiple hits: 40