BLASTP 2.12.0+
Reference: Stephen F. Altschul, Thomas L. Madden, Alejandro A.
Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J.
Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of
protein database search programs", Nucleic Acids Res. 25:3389-3402.
Reference for composition-based statistics: Alejandro A. Schaffer,
L. Aravind, Thomas L. Madden, Sergei Shavirin, John L. Spouge, Yuri
I. Wolf, Eugene V. Koonin, and Stephen F. Altschul (2001),
"Improving the accuracy of PSI-BLAST protein database searches with
composition-based statistics and other refinements", Nucleic Acids
Res. 29:2994-3005.
Database: 8d5f60da9b903927f467588d55b1a4b3.SwissProt.fasta
13 sequences; 5,142 total letters
Query= ACIAD1184
Length=437
Score E
Sequences producing significant alignments: (Bits) Value
P0AEB3 D-alanyl-D-alanine carboxypeptidase DacA [Escherichia coli... 171 2e-52
P0AEB4 D-alanyl-D-alanine carboxypeptidase DacA [Escherichia coli... 171 2e-52
P0AEB2 D-alanyl-D-alanine carboxypeptidase DacA [Escherichia coli... 171 2e-52
P08506 D-alanyl-D-alanine carboxypeptidase DacC [Escherichia coli... 171 4e-52
P38422 D-alanyl-D-alanine carboxypeptidase DacF [Bacillus subtili... 168 2e-51
P44466 D-alanyl-D-alanine carboxypeptidase DacA [Haemophilus infl... 166 1e-50
P37604 D-alanyl-D-alanine carboxypeptidase DacD [Salmonella typhi... 159 5e-48
P33013 D-alanyl-D-alanine carboxypeptidase DacD [Escherichia coli... 153 1e-45
P35150 D-alanyl-D-alanine carboxypeptidase DacB [Bacillus subtili... 120 2e-33
Q05523 D-alanyl-D-alanine carboxypeptidase DacA [Geobacillus stea... 115 2e-31
P08750 D-alanyl-D-alanine carboxypeptidase DacA [Bacillus subtili... 105 3e-28
O53380 D-alanyl-D-alanine carboxypeptidase DacB1 [Mycobacterium t... 93.6 4e-24
I6Y204 D-alanyl-D-alanine carboxypeptidase DacB2 [Mycobacterium t... 87.8 9e-23
>P0AEB3 D-alanyl-D-alanine carboxypeptidase DacA [Escherichia
coli O6:H1 (strain CFT073 / ATCC 700928 / UPEC)]
Length=403
Score = 171 bits (434), Expect = 2e-52
Identities = 124/426 (29%), Positives = 202/426 (47%), Gaps = 53/426 (12%)
Query 8 LSLFSLLCA---SVAHANLLNIAP-----ESVEAEAWSIVDAQSGQIISEHNSHIQRAPA 59
L+L + LC S AHA+ LNI ++AE++ ++D SG++++E N+ ++R PA
Sbjct 13 LALTTALCTAFISAAHADDLNIKTMIPGVPQIDAESYILIDYNSGKVLAEQNADVRRDPA 72
Query 60 SLTKMMVAYITLKELKAGKLHKTDILT----ATPVVNMVMWDESQMYLKPGEQISIDQLL 115
SLTKMM +Y+ + +KAGK +TD++T A N V S M+LKPG Q+ + QL+
Sbjct 73 SLTKMMTSYVIGQAMKAGKFKETDLVTIGNDAWATGNPVFKGSSLMFLKPGMQVPVSQLI 132
Query 116 AGLIVMSANDAAVTLAERISGNVPDFLKRMNQEAQALGMKDTYFSNPAGVTMPDHYSTSH 175
G+ + S NDA V +A+ +G+ F+ MN ALG+K+T+F G+ YS++
Sbjct 133 RGINLQSGNDACVAMADFAAGSQDAFVGLMNSYVNALGLKNTHFQTVHGLDADGQYSSAR 192
Query 176 DLALLAQAIVKQTPDYLSYSKLPSFSYQQ-RFHRATNLALKIDPTADGLKTGYTKAAGYN 234
D+AL+ QA+++ P+ S K F++ R L DG+KTG+T AGYN
Sbjct 193 DMALIGQALIRDVPNEYSIYKEKEFTFNGIRQLNRNGLLWDNSLNVDGIKTGHTDKAGYN 252
Query 235 LALTAKRPTMNVDIPDRRMIVVVLGTKNAHKRAEVANKLMNLAYAYTRDEEVIKNNQTIA 294
L +A M R+I V+G + R + KL+ + + +K + A
Sbjct 253 LVASATEGQM-------RLISAVMGGRTFKGREAESKKLLTWGFRFFETVNPLKVGKEFA 305
Query 295 ELPVIKSTLKMFKVETHQPTVVTTSLYNQPQAIDLNNFDNVTQRLYLPLGNGQKQLLEPL 354
PV + L V + +YL + G+ +
Sbjct 306 SEPV---------------------WFGDSDRASL----GVDKDVYLTIPRGRMK----- 335
Query 355 ETTNTRINVELNEQQLTAPLMKAINLATIQIYQNNQLIHSVQIADNVHIEEANFFQRFFM 414
+ + + LN +L APL K + TI + + I + I E NFF +
Sbjct 336 ---DLKASYVLNSSELHAPLQKNQVVGTINFQLDGKTIEQRPLVVLQEIPEGNFFGKIID 392
Query 415 WVKGIF 420
++K +F
Sbjct 393 YIKLMF 398
>P0AEB4 D-alanyl-D-alanine carboxypeptidase DacA [Escherichia
coli O157:H7]
Length=403
Score = 171 bits (434), Expect = 2e-52
Identities = 124/426 (29%), Positives = 202/426 (47%), Gaps = 53/426 (12%)
Query 8 LSLFSLLCA---SVAHANLLNIAP-----ESVEAEAWSIVDAQSGQIISEHNSHIQRAPA 59
L+L + LC S AHA+ LNI ++AE++ ++D SG++++E N+ ++R PA
Sbjct 13 LALTTALCTAFISAAHADDLNIKTMIPGVPQIDAESYILIDYNSGKVLAEQNADVRRDPA 72
Query 60 SLTKMMVAYITLKELKAGKLHKTDILT----ATPVVNMVMWDESQMYLKPGEQISIDQLL 115
SLTKMM +Y+ + +KAGK +TD++T A N V S M+LKPG Q+ + QL+
Sbjct 73 SLTKMMTSYVIGQAMKAGKFKETDLVTIGNDAWATGNPVFKGSSLMFLKPGMQVPVSQLI 132
Query 116 AGLIVMSANDAAVTLAERISGNVPDFLKRMNQEAQALGMKDTYFSNPAGVTMPDHYSTSH 175
G+ + S NDA V +A+ +G+ F+ MN ALG+K+T+F G+ YS++
Sbjct 133 RGINLQSGNDACVAMADFAAGSQDAFVGLMNSYVNALGLKNTHFQTVHGLDADGQYSSAR 192
Query 176 DLALLAQAIVKQTPDYLSYSKLPSFSYQQ-RFHRATNLALKIDPTADGLKTGYTKAAGYN 234
D+AL+ QA+++ P+ S K F++ R L DG+KTG+T AGYN
Sbjct 193 DMALIGQALIRDVPNEYSIYKEKEFTFNGIRQLNRNGLLWDNSLNVDGIKTGHTDKAGYN 252
Query 235 LALTAKRPTMNVDIPDRRMIVVVLGTKNAHKRAEVANKLMNLAYAYTRDEEVIKNNQTIA 294
L +A M R+I V+G + R + KL+ + + +K + A
Sbjct 253 LVASATEGQM-------RLISAVMGGRTFKGREAESKKLLTWGFRFFETVNPLKVGKEFA 305
Query 295 ELPVIKSTLKMFKVETHQPTVVTTSLYNQPQAIDLNNFDNVTQRLYLPLGNGQKQLLEPL 354
PV + L V + +YL + G+ +
Sbjct 306 SEPV---------------------WFGDSDRASL----GVDKDVYLTIPRGRMK----- 335
Query 355 ETTNTRINVELNEQQLTAPLMKAINLATIQIYQNNQLIHSVQIADNVHIEEANFFQRFFM 414
+ + + LN +L APL K + TI + + I + I E NFF +
Sbjct 336 ---DLKASYVLNSSELHAPLQKNQVVGTINFQLDGKTIEQRPLVVLQEIPEGNFFGKIID 392
Query 415 WVKGIF 420
++K +F
Sbjct 393 YIKLMF 398
>P0AEB2 D-alanyl-D-alanine carboxypeptidase DacA [Escherichia
coli (strain K12)]
Length=403
Score = 171 bits (434), Expect = 2e-52
Identities = 124/426 (29%), Positives = 202/426 (47%), Gaps = 53/426 (12%)
Query 8 LSLFSLLCA---SVAHANLLNIAP-----ESVEAEAWSIVDAQSGQIISEHNSHIQRAPA 59
L+L + LC S AHA+ LNI ++AE++ ++D SG++++E N+ ++R PA
Sbjct 13 LALTTALCTAFISAAHADDLNIKTMIPGVPQIDAESYILIDYNSGKVLAEQNADVRRDPA 72
Query 60 SLTKMMVAYITLKELKAGKLHKTDILT----ATPVVNMVMWDESQMYLKPGEQISIDQLL 115
SLTKMM +Y+ + +KAGK +TD++T A N V S M+LKPG Q+ + QL+
Sbjct 73 SLTKMMTSYVIGQAMKAGKFKETDLVTIGNDAWATGNPVFKGSSLMFLKPGMQVPVSQLI 132
Query 116 AGLIVMSANDAAVTLAERISGNVPDFLKRMNQEAQALGMKDTYFSNPAGVTMPDHYSTSH 175
G+ + S NDA V +A+ +G+ F+ MN ALG+K+T+F G+ YS++
Sbjct 133 RGINLQSGNDACVAMADFAAGSQDAFVGLMNSYVNALGLKNTHFQTVHGLDADGQYSSAR 192
Query 176 DLALLAQAIVKQTPDYLSYSKLPSFSYQQ-RFHRATNLALKIDPTADGLKTGYTKAAGYN 234
D+AL+ QA+++ P+ S K F++ R L DG+KTG+T AGYN
Sbjct 193 DMALIGQALIRDVPNEYSIYKEKEFTFNGIRQLNRNGLLWDNSLNVDGIKTGHTDKAGYN 252
Query 235 LALTAKRPTMNVDIPDRRMIVVVLGTKNAHKRAEVANKLMNLAYAYTRDEEVIKNNQTIA 294
L +A M R+I V+G + R + KL+ + + +K + A
Sbjct 253 LVASATEGQM-------RLISAVMGGRTFKGREAESKKLLTWGFRFFETVNPLKVGKEFA 305
Query 295 ELPVIKSTLKMFKVETHQPTVVTTSLYNQPQAIDLNNFDNVTQRLYLPLGNGQKQLLEPL 354
PV + L V + +YL + G+ +
Sbjct 306 SEPV---------------------WFGDSDRASL----GVDKDVYLTIPRGRMK----- 335
Query 355 ETTNTRINVELNEQQLTAPLMKAINLATIQIYQNNQLIHSVQIADNVHIEEANFFQRFFM 414
+ + + LN +L APL K + TI + + I + I E NFF +
Sbjct 336 ---DLKASYVLNSSELHAPLQKNQVVGTINFQLDGKTIEQRPLVVLQEIPEGNFFGKIID 392
Query 415 WVKGIF 420
++K +F
Sbjct 393 YIKLMF 398
>P08506 D-alanyl-D-alanine carboxypeptidase DacC [Escherichia
coli (strain K12)]
Length=400
Score = 171 bits (432), Expect = 4e-52
Identities = 125/421 (30%), Positives = 193/421 (46%), Gaps = 61/421 (14%)
Query 9 SLFSLLCASVAHANLLNIAPESVEAEAWSIVDAQSGQIISEHNSHIQRAPASLTKMMVAY 68
S F L A A A + SV+A AW ++D SG++++E N+ + PASLTK+M +Y
Sbjct 15 SAFLFLFAPTAFAAEQTVEAPSVDARAWILMDYASGKVLAEGNADEKLDPASLTKIMTSY 74
Query 69 ITLKELKAGKLHKTDILT----ATPVVNMVMWDESQMYLKPGEQISIDQLLAGLIVMSAN 124
+ + LKA K+ TD++T A N + S M+LKPG+Q+S+ L G+I+ S N
Sbjct 75 VVGQALKADKIKLTDMVTVGKDAWATGNPALRGSSVMFLKPGDQVSVADLNKGVIIQSGN 134
Query 125 DAAVTLAERISGNVPDFLKRMNQEAQALGMKDTYFSNPAGVTMPDHYSTSHDLALLAQAI 184
DA + LA+ ++G+ F+ MN A+ LG+ +T F G+ P +ST+ D+ALL +A+
Sbjct 135 DACIALADYVAGSQESFIGLMNGYAKKLGLTNTTFQTVHGLDAPGQFSTARDMALLGKAL 194
Query 185 VKQTPDYLSYSKLPSFSYQQ-RFHRATNLALKIDPTADGLKTGYTKAAGYNLALTAKRPT 243
+ P+ + K F++ + R L + DG+KTG T AGYNL +A +
Sbjct 195 IHDVPEEYAIHKEKEFTFNKIRQPNRNRLLWSSNLNVDGMKTGTTAGAGYNLVASATQ-- 252
Query 244 MNVDIPDRRMIVVVLGTKNAHKRAEVANKLMNLAYAYTRDEEVIKNNQTIAELPVIKSTL 303
D R+I VVLG K R + KL+ + + IK + T
Sbjct 253 -----GDMRLISVVLGAKTDRIRFNESEKLLTWGFRFFETVTPIKPDATF---------- 297
Query 304 KMFKVETHQPTVVTTSLYNQPQAIDLNNFDNVTQRLY--------LPLGNGQKQLLEPLE 355
VTQR++ L G + +
Sbjct 298 -------------------------------VTQRVWFGDKSEVNLGAGEAGSVTIPRGQ 326
Query 356 TTNTRINVELNEQQLTAPLMKAINLATIQIYQNNQLIHSVQIADNVHIEEANFFQRFFMW 415
N + + L E QLTAPL K + TI N + I + ++EE FF R + +
Sbjct 327 LKNLKASYTLTEPQLTAPLKKGQVVGTIDFQLNGKSIEQRPLIVMENVEEGGFFGRVWDF 386
Query 416 V 416
V
Sbjct 387 V 387
>P38422 D-alanyl-D-alanine carboxypeptidase DacF [Bacillus subtilis
(strain 168)]
Length=389
Score = 168 bits (426), Expect = 2e-51
Identities = 98/294 (33%), Positives = 172/294 (59%), Gaps = 19/294 (6%)
Query 32 EAEAWSIVDAQSGQIISEHNSHIQRAPASLTKMMVAYITLKELKAGKLHKTD-ILTATPV 90
EA++ +++ +G+++ NS+ + APAS+TK+M + ++ L GK+ +D + T+
Sbjct 36 EAKSAVLIERDTGKVLYNKNSNERLAPASMTKIMTMLLIMEALDKGKIKMSDKVRTSEHA 95
Query 91 VNMVMWDESQMYLKPGEQISIDQLLAGLIVMSANDAAVTLAERISGNVPDFLKRMNQEAQ 150
+M SQ++L+PGE++++ ++L G+ + S NDA+V +AE ISG+ +F+K+MN++A+
Sbjct 96 ASM---GGSQIFLEPGEEMTVKEMLKGIAIASGNDASVAMAEFISGSEEEFVKKMNKKAK 152
Query 151 ALGMKDTYFSNPAGVTMPDHYSTSHDLALLA------QAIVKQTPDYLSYSKLPSFSYQQ 204
LG+K+T F NP G+T HYS+++D+A++A ++I K T Y Y L + ++
Sbjct 153 ELGLKNTSFKNPTGLTEEGHYSSAYDMAIMAKELLKYESITKFTGTYEDY--LRENTDKK 210
Query 205 RFHRATNLALKIDPTADGLKTGYTKAAGYNLALTAKRPTMNVDIPDRRMIVVVLGTKNAH 264
+ TN +K P DG+KTGYT A Y L +AK+ M R I VV G
Sbjct 211 FWLVNTNRLIKFYPGVDGVKTGYTGEAKYCLTASAKKGNM-------RAIAVVFGASTPK 263
Query 265 KRAEVANKLMNLAYAYTRDEEVIKNNQTIAELPVIKSTLKMFKVETHQPTVVTT 318
+R K+++ A++ + K NQT+A++ V K K ++ T +P + T
Sbjct 264 ERNAQVTKMLDFAFSQYETHPLYKRNQTVAKVKVKKGKQKFIELTTSEPISILT 317
>P44466 D-alanyl-D-alanine carboxypeptidase DacA [Haemophilus
influenzae (strain ATCC 51907 / DSM 11121 / KW20 / Rd)]
Length=393
Score = 166 bits (421), Expect = 1e-50
Identities = 126/431 (29%), Positives = 207/431 (48%), Gaps = 65/431 (15%)
Query 5 FSILSLFSLLCASVAHANLLNIAPESVEAEAWSIVDAQSGQIISEHNSHIQRAPASLTKM 64
F LS FS+ + + P + A+ + ++D SG I++ N ++ PASLTKM
Sbjct 14 FVALSAFSVSAEDMQ----FGVTPPQITAQTYVLMDYNSGAILTALNPDQRQYPASLTKM 69
Query 65 MVAYITLKELKAGKLHKTDILTATPVVNMVMW-----DESQMYLKPGEQISIDQLLAGLI 119
M +Y+ LK GK+H TD++T + W D S+M+L Q+S+ L G+I
Sbjct 70 MTSYVVGVALKQGKIHNTDMVT----IGESAWGRNFPDSSKMFLDLNTQVSVADLNRGVI 125
Query 120 VMSANDAAVTLAERISGNVPDFLKRMNQEAQALGMKDTYFSNPAGVTMPDHYSTSHDLAL 179
V+S NDA V LAE ISGNVP+F++ MN+ Q G+K+T F+ P G+ P+ YS++ D+A+
Sbjct 126 VVSGNDATVALAEHISGNVPNFVETMNKYVQQFGLKNTNFTTPHGLDDPNQYSSARDMAI 185
Query 180 LAQAIVKQTPDYLSYSKLPSFSYQQRFHRATNLALKIDPT--ADGLKTGYTKAAGYNLAL 237
+ I++ P+ +F++ + +A L D T DG+KTG+T AGYNL
Sbjct 186 IGAHIIRDLPEEYKIYSEKNFTF-NKIKQANRNGLLWDKTINVDGMKTGHTSQAGYNLVA 244
Query 238 TAKRPTMNVDIPDRRMIVVVLGTKNAHKRAEVANKLMNLAYAYTRDEEVIKNNQTIAELP 297
+A T N + R+I VV+G R + KL+ +A + ++ + I+E
Sbjct 245 SA--TTSN----NMRLISVVMGVPTYKGREVESKKLLQWGFANFETFKTLEAGKEISEQR 298
Query 298 VI---KSTLKMFKVETHQPTVVTTSLYNQPQAIDLNNFDNVTQRLYLPLGNGQKQLLEPL 354
V K+++K+ + H T+ P G
Sbjct 299 VYYGDKNSVKLGALMDHFITI--------------------------PKG---------- 322
Query 355 ETTNTRINVELNEQQLTAPLMKAINLATIQIYQNNQLIHSVQIADNVHIEEANFFQRFFM 414
+ + + EL ++ L APL+K + + + + I S + + EA F + +
Sbjct 323 KQSEVKARYELADKNLQAPLVKGQVIGKVVYQLDGKDIASANLQVMNDVGEAGIFGKLWD 382
Query 415 W----VKGIFS 421
W VKG+FS
Sbjct 383 WLVLTVKGLFS 393
>P37604 D-alanyl-D-alanine carboxypeptidase DacD [Salmonella typhimurium
(strain LT2 / SGSC1412 / ATCC 700720)]
Length=390
Score = 159 bits (403), Expect = 5e-48
Identities = 101/281 (36%), Positives = 159/281 (57%), Gaps = 16/281 (6%)
Query 2 RLFFSILSLFSLLCASVAHANLLNIAPE--SVEAEAWSIVDAQSGQIISEHNSHIQRAPA 59
R F SLF++ + A+ ++ AP+ +++A AW ++D +GQ+++ N H QR PA
Sbjct 5 RRLFIAASLFAMHLSPALAADAVSFAPQPPAIDAGAWVLMDYTTGQVLTAGNEHQQRNPA 64
Query 60 SLTKMMVAYITLKELKAGKLHKTDILT----ATPVVNMVMWDESQMYLKPGEQISIDQLL 115
SLTK+M Y+ + + + ++ DI+T A N V S M+LK G+++S+ L
Sbjct 65 SLTKLMTGYVVDRAIDSHRISPDDIVTVGRDAWAKDNPVFVGSSLMFLKEGDRVSVRDLS 124
Query 116 AGLIVMSANDAAVTLAERISGNVPDFLKRMNQEAQALGMKDTYFSNPAGVTMPDHYSTSH 175
GLIV S NDA V LA+ I+G P F+ MN + L ++DT+F G+ P +S+++
Sbjct 125 RGLIVDSGNDACVALADYIAGGQPQFVAMMNSYVKKLNLQDTHFETVHGLDAPGQHSSAY 184
Query 176 DLALLAQAIVKQTPDYLSYSKLPSFSYQQRFHRATNLALKIDPT--ADGLKTGYTKAAGY 233
DLA+L++AI+ P++ S ++ + N L D T DGLKTG+T AG+
Sbjct 185 DLAVLSRAIIHGEPEFYHMYSEKSLTWNGITQQNRN-GLLWDKTMHIDGLKTGHTSGAGF 243
Query 234 NLALTAKRPTMNVDIPDRRMIVVVLGTKNAHKRAEVANKLM 274
NL +A VD RR+I VV+G K++ R E A KL+
Sbjct 244 NLIASA------VD-GQRRLIAVVMGAKSSKGREEQARKLL 277
>P33013 D-alanyl-D-alanine carboxypeptidase DacD [Escherichia
coli (strain K12)]
Length=388
Score = 153 bits (386), Expect = 1e-45
Identities = 119/410 (29%), Positives = 194/410 (47%), Gaps = 47/410 (11%)
Query 8 LSLFSLLCASVAHANLLNIAPESVEAEAWSIVDAQSGQIISEHNSHIQRAPASLTKMMVA 67
L +F+L A + P + A +W ++D +GQI++ N H QR PASLTK+M
Sbjct 11 LFVFNLSSGFAAENIPFSPQPPEIHAGSWVLMDYTTGQILTAGNEHQQRNPASLTKLMTG 70
Query 68 YITLKELKAGKLHKTDILT----ATPVVNMVMWDESQMYLKPGEQISIDQLLAGLIVMSA 123
Y+ + + + ++ DI+T A N V S M+LK G+++S+ L GLIV S
Sbjct 71 YVVDRAIDSHRITPDDIVTVGRDAWAKDNPVFVGSSLMFLKEGDRVSVRDLSRGLIVDSG 130
Query 124 NDAAVTLAERISGNVPDFLKRMNQEAQALGMKDTYFSNPAGVTMPDHYSTSHDLALLAQA 183
NDA V LA+ I+G F++ MN A+ L +KDT+F G+ P +S+++DLA+L++A
Sbjct 131 NDACVALADYIAGGQRQFVEMMNNYAEKLHLKDTHFETVHGLDAPGQHSSAYDLAVLSRA 190
Query 184 IVKQTPDYLSYSKLPSFSYQQRFHRATNLALKIDPT--ADGLKTGYTKAAGYNLALTAKR 241
I+ P++ S ++ + N L D T DGLKTG+T AG+NL +A
Sbjct 191 IIHGEPEFYHMYSEKSLTWNGITQQNRN-GLLWDKTMNVDGLKTGHTSGAGFNLIASA-- 247
Query 242 PTMNVDIPDRRMIVVVLGTKNAHKRAEVANKLMNLAYAYTRDEEVIKNNQTIAELPVIKS 301
VD RR+I VV+G +A R E A KL+ +++ +
Sbjct 248 ----VD-GQRRLIAVVMGADSAKGREEEARKLLRWGQQNFTTVQILHRGK---------- 292
Query 302 TLKMFKVETHQPTVVTTSLYNQPQAIDLNNFDNVTQRLYLPLGNGQKQLLEPLETTNTRI 361
KV T + Y + IDL Q ++ +L E + +
Sbjct 293 -----KVGTER------IWYGDKENIDL----GTEQEFWM--------VLPKAEIPHIKA 329
Query 362 NVELNEQQLTAPLMKAINLATIQIYQNNQLIHSVQIADNVHIEEANFFQR 411
L+ ++LTAP+ + I++Y ++ + + + E + F R
Sbjct 330 KYTLDGKELTAPISAHQRVGEIELYDRDKQVAHWPLVTLESVGEGSMFSR 379
>P35150 D-alanyl-D-alanine carboxypeptidase DacB [Bacillus subtilis
(strain 168)]
Length=382
Score = 120 bits (300), Expect = 2e-33
Identities = 78/236 (33%), Positives = 132/236 (56%), Gaps = 18/236 (8%)
Query 10 LFSLLCASVAHANLLNIAPESVEAEAWSIVDAQSGQIISEHNSHIQRAPASLTKMMVAYI 69
L + + + AHA + V A++ I+D SG+++ + H +R AS+TK+M A +
Sbjct 16 LIATVNVNTAHAAI------DVSAKSAIIIDGASGRVLYAKDEHQKRRIASITKIMTAVL 69
Query 70 TLKELKAGKLHKTDILTATPVVNMVMWDESQMYLKPGEQISIDQLLAGLIVMSANDAAVT 129
++ +GK+ +T ++A N V + S +YL G+++ + L+ GL++ S NDAAV
Sbjct 70 AIE---SGKMDQTVTVSA----NAVRTEGSAIYLTEGQKVKLKDLVYGLMLRSGNDAAVA 122
Query 130 LAERISGNVPDFLKRMNQEAQALGMKDTYFSNPAGV-TMPDHYSTSHDLALLAQAIVKQT 188
+AE + G++ F+ MNQ+A+ LGMK+T F NP G+ +HYST++D+A+L + +K
Sbjct 123 IAEHVGGSLDGFVYMMNQKAEQLGMKNTRFQNPHGLDDHENHYSTAYDMAILTKYAMK-L 181
Query 189 PDYLSYSKLPSF---SYQQRFHRATNLALKIDPTADGLKTGYTKAAGYNLALTAKR 241
DY S + + + + L + P + G KTGYTK A L TA +
Sbjct 182 KDYQKISGTKIYKAETMESVWKNKNKLLTMLYPYSTGGKTGYTKLAKRTLVSTASK 237
>Q05523 D-alanyl-D-alanine carboxypeptidase DacA [Geobacillus
stearothermophilus]
Length=452
Score = 115 bits (287), Expect = 2e-31
Identities = 118/443 (27%), Positives = 196/443 (44%), Gaps = 87/443 (20%)
Query 27 APESVEAEAWSIVDAQSGQIISEHNSHIQRAPASLTKMMVAYITLKELKAGKLHKTDILT 86
AP + A+A +VDAQ+G+I+ E N AS+TKMM Y+ L +KA ++ + T
Sbjct 33 APLDIRADAAILVDAQTGRILYEKNIDTVLGIASMTKMMTEYLLLDAIKAKRVKWDQMYT 92
Query 87 ATPVVNMVMWDE--SQMYLKPGEQISIDQLLAGLIVMSANDAAVTLAERISGNVPDFLKR 144
+ V + D S + L+ + ++ +L + + SAN A V +AE I+G+ +F+K
Sbjct 93 PSDYVYRLSQDRALSNVPLRKDGKYTVRELYEAMAIYSANGATVAIAEIIAGSEKNFVKM 152
Query 145 MNQEAQALGMKDTYFSNPAGVT-------MPDHYSTSHD-------LALLAQAIVKQTPD 190
MN +A+ LG+KD F N G++ P+ ST+ + +A+LA ++K P+
Sbjct 153 MNDKAKELGLKDYKFVNATGLSNKDLKGFHPEGTSTNEENVMSARAMAMLAYRLLKDHPE 212
Query 191 YLSYSKLPSFSYQQRFHRATNLALKID-------------PTADGLKTGYTKAAGYNLAL 237
L + +P + F T +K+D DGLKTGYT+ AG
Sbjct 213 VLKTASIP----HKVFREGTKDEIKMDNWNWMLPGLVYGYEGVDGLKTGYTEFAGNCFTG 268
Query 238 TAKRPTMNVDIPDRRMIVVVLGTKNA------HKRAEVANKLMNLAY-AYTRDEEVIKNN 290
TAKR + R+I VV+ K+A R + KL N + Y+ + K
Sbjct 269 TAKRNGV-------RLISVVMNAKDASGKTTKEARFKETEKLFNYGFNQYSLETLYPKGY 321
Query 291 QTIAE--LPVIKSTLKMFKVETHQPTVVTTSLYNQPQAIDLNNFDNVTQRLYLPLGNGQK 348
Q + LPV+K K +V T + L L + NG++
Sbjct 322 QLKGKETLPVVKGKEKEVRVAT-------------------------GKNLDLLVKNGEE 356
Query 349 QLLEPLETTNTRINVELNEQQLTAPLMK--AINLATIQIYQNNQLIH---------SVQI 397
+ +P+ + + + E +L APL K + T++ ++ L V +
Sbjct 357 KQYKPVYVLDKKKMTK--EGKLVAPLKKGETVGYMTLEYKGDDSLAFLSPDMQKNIRVPL 414
Query 398 ADNVHIEEANFFQRFFMWVKGIF 420
+E+AN+F V G+F
Sbjct 415 VTTAEVEKANWFVLSMRAVGGLF 437
>P08750 D-alanyl-D-alanine carboxypeptidase DacA [Bacillus subtilis
(strain 168)]
Length=443
Score = 105 bits (263), Expect = 3e-28
Identities = 104/432 (24%), Positives = 183/432 (42%), Gaps = 75/432 (17%)
Query 28 PESVEAEAWSIVDAQSGQIISEHNSHIQRAPASLTKMMVAYITLKELKAGKLHKTDILTA 87
P + A A +++A SG+I+ N+ + AS+TKMM Y+ L+ + GK+ T
Sbjct 35 PIDINASAAIMIEASSGKILYSKNADKRLPIASMTKMMTEYLLLEAIDQGKVKWDQTYTP 94
Query 88 TPVVNMVMWDES--QMYLKPGEQISIDQLLAGLIVMSANDAAVTLAERISGNVPDFLKRM 145
V + D S + L+ + ++ +L + SAN AA+ +AE ++G+ F+++M
Sbjct 95 DDYVYEISQDNSLSNVPLRKDGKYTVKELYQATAIYSANAAAIAIAEIVAGSETKFVEKM 154
Query 146 NQEAQALGMKDTYFSNPAGVTMPDHYS--------------TSHDLALLAQAIVKQTPDY 191
N +A+ LG+ D F N G+ D + ++ D+A+LA ++ P+
Sbjct 155 NAKAKELGLTDYKFVNATGLENKDLHGHQPEGTSVNEESEVSAKDMAVLADHLITDYPEI 214
Query 192 LSYSKLPSFSYQQRFHRAT-----NLALK------IDPTADGLKTGYTKAAGYNLALTAK 240
L S + +++ N LK T DGLKTG T +AG TA+
Sbjct 215 LETSSIAKTKFREGTDDEMDMPNWNFMLKGLVSEYKKATVDGLKTGSTDSAGSCFTGTAE 274
Query 241 RPTMNVDIPDRRMIVVVLGTK-NAHK-RAEVANKLMNLAYAYTRDEEVIKNNQTIAELPV 298
R M R+I VVL K N H R + K+ + A+ +E+ +
Sbjct 275 RNGM-------RVITVVLNAKGNLHTGRFDETKKMFDYAFDNFSMKEIYAEGDQVKG--- 324
Query 299 IKSTLKMFKVETHQPTVVTTSLYNQPQAIDLNNFDNVTQRLYLPLGNGQKQLLEPLETTN 358
T+ + K + + +VT ++ LP+ NG+++ N
Sbjct 325 -HKTISVDKGKEKEVGIVTNKAFS------------------LPVKNGEEK--------N 357
Query 359 TRINVELNEQQLTAPLMKAINLATIQIYQN---------NQLIHSVQIADNVHIEEANFF 409
+ V LN+ LTAP+ K + + N + V + ++E+AN+F
Sbjct 358 YKAKVTLNKDNLTAPVKKGTKVGKLTAEYTGDEKDYGFLNSDLAGVDLVTKENVEKANWF 417
Query 410 QRFFMWVKGIFS 421
+ G F+
Sbjct 418 VLTMRSIGGFFA 429
>O53380 D-alanyl-D-alanine carboxypeptidase DacB1 [Mycobacterium
tuberculosis (strain ATCC 25618 / H37Rv)]
Length=405
Score = 93.6 bits (231), Expect = 4e-24
Identities = 74/263 (28%), Positives = 124/263 (47%), Gaps = 31/263 (12%)
Query 27 APESVEAEAWSIVDAQSGQIISEHNSHIQRAPASLTKMMVAYITLKELKAGKLHKTDILT 86
AP V AEAW + D SG +I+ + H + PAS+ K++VA ++ L K +
Sbjct 88 APGDVSAEAWLVADLDSGAVIAARDPHGRHRPASVIKVLVAMASINTLTLNK-------S 140
Query 87 ATPVVNMVMWDESQMYLKPGEQISIDQLLAGLIVMSANDAAVTLAERISGNVPDFLKRMN 146
+ + +++ + G +++QLL GL++ S NDAA LA ++ G +P L+++N
Sbjct 141 VAGTADDAAVEGTKVGVNTGGTYTVNQLLHGLLMHSGNDAAYALARQL-GGMPAALEKIN 199
Query 147 QEAQALGMKDTYFSNPAGVTMPDHYSTSHDLAL----------LAQAIVKQTPDYLSYSK 196
A LG +DT + P+G+ P ++++D+ L A + +T D+ +
Sbjct 200 LLAAKLGGRDTRVATPSGLDGPGMSTSAYDIGLFYRYAWQNPVFADIVATRTFDFPGHGD 259
Query 197 LPSFSYQQRFHRATNLALKIDPTADGLKTGYTKAAGYNLALTAKRPTMNVDIPDRRMIVV 256
P + + N L P A G KTGYT AG A R RR++ V
Sbjct 260 HPGYELEN-----DNQLLYNYPGALGGKTGYTDDAGQTFVGAANR-------DGRRLMTV 307
Query 257 VL-GTKNAHKRAEVANKLMNLAY 278
+L GT+ E A L++ +
Sbjct 308 LLHGTRQPIPPWEQAAHLLDYGF 330
>I6Y204 D-alanyl-D-alanine carboxypeptidase DacB2 [Mycobacterium
tuberculosis (strain ATCC 25618 / H37Rv)]
Length=291
Score = 87.8 bits (216), Expect = 9e-23
Identities = 66/206 (32%), Positives = 100/206 (49%), Gaps = 17/206 (8%)
Query 33 AEAWSIVDAQSGQIISEHNSHIQRAPASLTKMMVAYITLKELKAGKLHKTDILTATPVVN 92
A+ W + D SGQ+++ + ++ PAS K+++A + L EL D+ N
Sbjct 42 AQTWIVADLDSGQVLAGRDQNVAHPPASTIKVLLALVALDELDLNSTVVADVADTQAECN 101
Query 93 MVMWDESQMYLKPGEQISIDQLLAGLIVMSANDAAVTLAERISGNVPDFLKRMNQEAQAL 152
V +KPG + QLL GL+++S NDAA TLA + G K MN +A L
Sbjct 102 CV-------GVKPGRSYTARQLLDGLLLVSGNDAANTLAHMLGGQDVTVAK-MNAKAATL 153
Query 153 GMKDTYFSNPAGVTMP--DHYSTSHDLALLAQAIVKQTPDYLSYSKLPSFSY-----QQR 205
G T+ + P+G+ P ST+HDL ++ +A + P + + PS + +Q
Sbjct 154 GATSTHATTPSGLDGPGGSGASTAHDLVVIFRAAM-ANPVFAQITAEPSAMFPSDNGEQL 212
Query 206 FHRATNLALKIDPTADGLKTGYTKAA 231
L L+ P A G KTGYT AA
Sbjct 213 IVNQDEL-LQRYPGAIGGKTGYTNAA 237
Lambda K H a alpha
0.320 0.132 0.375 0.792 4.96
Gapped
Lambda K H a alpha sigma
0.267 0.0410 0.140 1.90 42.6 43.6
Effective search space used: 1747940
Database: 8d5f60da9b903927f467588d55b1a4b3.SwissProt.fasta
Posted date: May 30, 2024 8:20 AM
Number of letters in database: 5,142
Number of sequences in database: 13
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Neighboring words threshold: 11
Window for multiple hits: 40
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Data ...
