BLASTP 2.12.0+
Reference: Stephen F. Altschul, Thomas L. Madden, Alejandro A.
Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J.
Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of
protein database search programs", Nucleic Acids Res. 25:3389-3402.
Reference for composition-based statistics: Alejandro A. Schaffer,
L. Aravind, Thomas L. Madden, Sergei Shavirin, John L. Spouge, Yuri
I. Wolf, Eugene V. Koonin, and Stephen F. Altschul (2001),
"Improving the accuracy of PSI-BLAST protein database searches with
composition-based statistics and other refinements", Nucleic Acids
Res. 29:2994-3005.
Database: 23f3b80c130b12dd5c694644082d0d2d.SwissProt.fasta
19 sequences; 8,610 total letters
Query= ACIAD1219
Length=463
Score E
Sequences producing significant alignments: (Bits) Value
Q9I0K9 Adenylosuccinate lyase [Pseudomonas aeruginosa (strain ATC... 636 0.0
P44797 Adenylosuccinate lyase [Haemophilus influenzae (strain ATC... 594 0.0
A0A0H3AL67 Adenylosuccinate lyase [Vibrio cholerae serotype O1 (s... 587 0.0
P0AB90 Adenylosuccinate lyase [Escherichia coli O6:H1 (strain CFT... 586 0.0
P0AB89 Adenylosuccinate lyase [Escherichia coli (strain K12)] 586 0.0
P57351 Adenylosuccinate lyase [Buchnera aphidicola subsp. Acyrtho... 484 8e-173
Q8K9Q7 Adenylosuccinate lyase [Buchnera aphidicola subsp. Schizap... 481 3e-171
A5IGB3 Adenylosuccinate lyase [Legionella pneumophila (strain Cor... 474 7e-169
Q5ZXD1 Adenylosuccinate lyase [Legionella pneumophila subsp. pneu... 473 3e-168
Q89AM3 Adenylosuccinate lyase [Buchnera aphidicola subsp. Baizong... 473 4e-168
Q54J34 Adenylosuccinate lyase [Dictyostelium discoideum] 379 3e-131
P12047 Adenylosuccinate lyase [Bacillus subtilis (strain 168)] 109 3e-29
Q9X0I0 Adenylosuccinate lyase [Thermotoga maritima (strain ATCC 4... 99.0 1e-25
Q7A0G9 Adenylosuccinate lyase [Staphylococcus aureus (strain MW2)] 92.8 2e-23
P32427 3-carboxy-cis,cis-muconate cycloisomerase [Pseudomonas put... 73.6 3e-17
P21265 Adenylosuccinate lyase [Gallus gallus] 63.9 5e-14
O31385 3-carboxy-cis,cis-muconate cycloisomerase [Bradyrhizobium ... 58.2 3e-12
P07343 Fumarate hydratase class II [Bacillus subtilis (strain 168)] 50.8 7e-10
P05042 Fumarate hydratase class II [Escherichia coli (strain K12)] 47.0 1e-08
>Q9I0K9 Adenylosuccinate lyase [Pseudomonas aeruginosa (strain
ATCC 15692 / DSM 22644 / CIP 104116 / JCM 14847 / LMG 12228
/ 1C / PRS 101 / PAO1)]
Length=456
Score = 636 bits (1641), Expect = 0.0
Identities = 322/457 (70%), Positives = 375/457 (82%), Gaps = 5/457 (1%)
Query 1 MNALTALSPLDGRYASKCDALRPFLSEFGLIHARVTVEVRWLQALSNHAGIIEVAPFSTE 60
+++LTA+SP+DGRYA K +LRP SE+GLI RV VEVRWLQ L+ HAGI EVAPFS E
Sbjct 3 LSSLTAVSPVDGRYAGKTSSLRPIFSEYGLIRFRVMVEVRWLQRLAAHAGIPEVAPFSAE 62
Query 61 TNAALDSIVANFSEDDANRIKEIERTTNHDVKAVEYFLKEKIAGLDELKNAGEFIHFACT 120
NA LDS+ ++F + A RIKEIERTTNHDVKAVEY LKE+ A L EL EFIHFACT
Sbjct 63 ANALLDSLASDFQLEHAERIKEIERTTNHDVKAVEYLLKEQAAKLPELAAVSEFIHFACT 122
Query 121 SEDINNLSHALMLKNGRE-VLVSSMKQILNAIAALATTHAEQPMLSRTHGQTASPTTLGK 179
SEDINNLSHALML+ GR+ VL+ M+QI AI LA A+ PMLSRTHGQ ASPTTLGK
Sbjct 123 SEDINNLSHALMLREGRDSVLLPLMRQIAEAIRELAVKLADVPMLSRTHGQPASPTTLGK 182
Query 180 EMANVAYRLARQIKQFENVELLGKINGAVGNYNAHLSAYPDIDWAAHSQAFVES-LGLTF 238
E+ANV YRL RQIKQ +ELLGKINGAVGNYNAHLSAYP++DW A+++ F+E LGLTF
Sbjct 183 ELANVVYRLERQIKQVAGIELLGKINGAVGNYNAHLSAYPEVDWEANARQFIEGDLGLTF 242
Query 239 NPYTTQIEPHDYMAELFDALRRYNTILIDFNRDVWGYISLGYFKQKLKDGEVGSSTMPHK 298
NPYTTQIEPHDY+AELFDA+ R+NTILIDF+RDVWGYISLGYFKQK GE+GSSTMPHK
Sbjct 243 NPYTTQIEPHDYIAELFDAIARFNTILIDFDRDVWGYISLGYFKQKTVAGEIGSSTMPHK 302
Query 299 VNPIDFENSEGNLGIANAVLGHLGEKLPVSRWQRDLTDSTVLRNMGVGFAQSLIAFDACL 358
VNPIDFENSEGNLGIANA+ HL KLP+SRWQRDLTDSTVLRN+GVG A S+IA++A L
Sbjct 303 VNPIDFENSEGNLGIANALFQHLASKLPISRWQRDLTDSTVLRNLGVGIAHSIIAYEASL 362
Query 359 KGIGKLELNAARLAEDLNQAQEVLAEPIQTVMRRYNVEKPYEKLKALTRGQAMTRDMMVN 418
KGIGKLELNA R+AEDL+ EVLAEP+QTVMRRY VE PYEKLK LTRG+ ++ + +
Sbjct 363 KGIGKLELNAQRIAEDLDACWEVLAEPVQTVMRRYGVENPYEKLKELTRGKGISAEALQT 422
Query 419 FVNGDELSQVPAEERARLAEMTPASYTGNAADQAKQI 455
F+ +EL+ +PAE + L ++TPA Y GNAA QAK+I
Sbjct 423 FI--EELA-IPAEAKVELKKLTPAGYVGNAAAQAKRI 456
>P44797 Adenylosuccinate lyase [Haemophilus influenzae (strain
ATCC 51907 / DSM 11121 / KW20 / Rd)]
Length=456
Score = 594 bits (1531), Expect = 0.0
Identities = 300/457 (66%), Positives = 358/457 (78%), Gaps = 4/457 (1%)
Query 1 MNALTALSPLDGRYASKCDALRPFLSEFGLIHARVTVEVRWLQALSNHAGIIEVAPFSTE 60
++ LTALSPLDGRY K LR SEFGL+ RV VEVRWLQ L++ A I EV PFST+
Sbjct 3 LSTLTALSPLDGRYQDKVTPLRAIFSEFGLMKFRVAVEVRWLQKLASTADITEVPPFSTQ 62
Query 61 TNAALDSIVANFSEDDANRIKEIERTTNHDVKAVEYFLKEKIAGLDELKNAGEFIHFACT 120
NA LD IVANF+E DA RIKEIERTTNHDVKAVEYFLKEKI EL EFIHFACT
Sbjct 63 ANAFLDGIVANFNEADAARIKEIERTTNHDVKAVEYFLKEKIQNEVELVKVSEFIHFACT 122
Query 121 SEDINNLSHALMLKNGR-EVLVSSMKQILNAIAALATTHAEQPMLSRTHGQTASPTTLGK 179
SEDINNLSHALML R EV++ +++++ I LA + P+LSRTHGQ ASP+T+GK
Sbjct 123 SEDINNLSHALMLSTARDEVILPEWQKLIDEITRLAEEYKTIPLLSRTHGQPASPSTVGK 182
Query 180 EMANVAYRLARQIKQFENVELLGKINGAVGNYNAHLSAYPDIDWAAHSQAFVESLGLTFN 239
EMANV YRL RQ KQ +N E+LGKINGAVGNYNAHLSAYP+IDW S+ FV SLG+ +N
Sbjct 183 EMANVVYRLKRQFKQLQNAEILGKINGAVGNYNAHLSAYPNIDWHKFSEEFVTSLGIQWN 242
Query 240 PYTTQIEPHDYMAELFDALRRYNTILIDFNRDVWGYISLGYFKQKLKDGEVGSSTMPHKV 299
PYTTQIEPHDY+ E FDA+ R+NTI+IDF+RD+WGYI+L +FKQ+ GE+GSSTMPHKV
Sbjct 243 PYTTQIEPHDYITEFFDAVVRFNTIIIDFDRDLWGYIALNHFKQRTIAGEIGSSTMPHKV 302
Query 300 NPIDFENSEGNLGIANAVLGHLGEKLPVSRWQRDLTDSTVLRNMGVGFAQSLIAFDACLK 359
NPIDFENSEGNLG+ANAV+ HLG+KLP+SRWQRDLTDSTVLRN+GVG LIA+ + K
Sbjct 303 NPIDFENSEGNLGLANAVMTHLGQKLPISRWQRDLTDSTVLRNLGVGLGYCLIAYASTRK 362
Query 360 GIGKLELNAARLAEDLNQAQEVLAEPIQTVMRRYNVEKPYEKLKALTRGQAMTRDMMVNF 419
GI KLE+N L E+LNQ EVLAEPIQTVMRRY +EKPYEKLK LTRG+ +T M F
Sbjct 363 GISKLEVNQPHLLEELNQNWEVLAEPIQTVMRRYGIEKPYEKLKELTRGKRVTEQAMREF 422
Query 420 VNGDELSQVPAEERARLAEMTPASYTGNAADQAKQIN 456
+ D+L +P EE+ RL ++TPA+Y G A + ++++
Sbjct 423 I--DKL-DIPQEEKLRLQKLTPATYIGAAVELVEKLS 456
>A0A0H3AL67 Adenylosuccinate lyase [Vibrio cholerae serotype O1
(strain ATCC 39541 / Classical Ogawa 395 / O395)]
Length=456
Score = 587 bits (1512), Expect = 0.0
Identities = 297/452 (66%), Positives = 356/452 (79%), Gaps = 5/452 (1%)
Query 1 MNALTALSPLDGRYASKCDALRPFLSEFGLIHARVTVEVRWLQALSNHAGIIEVAPFSTE 60
++ALTA+SP+DGRY SK ALR SEFGL+ R VE+RWLQ L+ A I EV FS E
Sbjct 3 LSALTAVSPVDGRYGSKTIALRSIFSEFGLLKYRTIVEIRWLQKLAATAEIAEVPAFSAE 62
Query 61 TNAALDSIVANFSEDDANRIKEIERTTNHDVKAVEYFLKEKIAGLDELKNAGEFIHFACT 120
N LD+I ANF+E DA RIKEIERTTNHDVKAVEYFLKEK+A + EL EFIHFACT
Sbjct 63 ANQFLDAIAANFNEADALRIKEIERTTNHDVKAVEYFLKEKVAAMPELHAVNEFIHFACT 122
Query 121 SEDINNLSHALMLKNGRE-VLVSSMKQILNAIAALATTHAEQPMLSRTHGQTASPTTLGK 179
SEDINN SHALMLK R+ V++ ++ +++AI LA + + P+LSRTHGQ ASP+T+GK
Sbjct 123 SEDINNTSHALMLKEARDTVILPEIRNVIDAIRKLAEEYRDIPLLSRTHGQPASPSTMGK 182
Query 180 EMANVAYRLARQIKQFENVELLGKINGAVGNYNAHLSAYPDIDWAAHSQAFV-ESLGLTF 238
EMANVAYR+ RQ KQ NVE+L KINGAVGNYNAHLSAYP +DW S+ F+ ESLG+ +
Sbjct 183 EMANVAYRMERQYKQIANVEILAKINGAVGNYNAHLSAYPTVDWHKFSEEFITESLGVDW 242
Query 239 NPYTTQIEPHDYMAELFDALRRYNTILIDFNRDVWGYISLGYFKQKLKDGEVGSSTMPHK 298
NPYTTQIEPHDY+AELF+A+ R+NTILIDF+RDVWGYI+LG+FKQ+ GE+GSSTMPHK
Sbjct 243 NPYTTQIEPHDYIAELFEAVARFNTILIDFDRDVWGYIALGHFKQRTIAGEIGSSTMPHK 302
Query 299 VNPIDFENSEGNLGIANAVLGHLGEKLPVSRWQRDLTDSTVLRNMGVGFAQSLIAFDACL 358
VNPIDFENSEGNLG+ANAV HL +KLP+SRWQRDLTDSTVLRN+GVG ++IA+ + L
Sbjct 303 VNPIDFENSEGNLGLANAVFTHLAQKLPISRWQRDLTDSTVLRNLGVGVGYAIIAYTSTL 362
Query 359 KGIGKLELNAARLAEDLNQAQEVLAEPIQTVMRRYNVEKPYEKLKALTRGQAMTRDMMVN 418
KGI KLE+N L +L+ EVLAEPIQTVMRRY +EKPYEKLK LTRG+ + + M
Sbjct 363 KGISKLEVNRDALLAELDHNWEVLAEPIQTVMRRYGIEKPYEKLKELTRGKRVDGEAMRQ 422
Query 419 FVNGDELSQVPAEERARLAEMTPASYTGNAAD 450
F++G L PAEE+ RL MTPASY G A +
Sbjct 423 FIDGLAL---PAEEKTRLKAMTPASYIGYAIE 451
>P0AB90 Adenylosuccinate lyase [Escherichia coli O6:H1 (strain
CFT073 / ATCC 700928 / UPEC)]
Length=456
Score = 586 bits (1511), Expect = 0.0
Identities = 292/456 (64%), Positives = 357/456 (78%), Gaps = 4/456 (1%)
Query 1 MNALTALSPLDGRYASKCDALRPFLSEFGLIHARVTVEVRWLQALSNHAGIIEVAPFSTE 60
+++LTA+SP+DGRY K ALR SE+GL+ RV VEVRWLQ L+ HA I EV F+ +
Sbjct 3 LSSLTAVSPVDGRYGDKVSALRGIFSEYGLLKFRVQVEVRWLQKLAAHAAIKEVPAFAAD 62
Query 61 TNAALDSIVANFSEDDANRIKEIERTTNHDVKAVEYFLKEKIAGLDELKNAGEFIHFACT 120
LD+IVA+FSE+DA RIK IERTTNHDVKAVEYFLKEK+A + EL EFIHFACT
Sbjct 63 AIGYLDAIVASFSEEDAARIKTIERTTNHDVKAVEYFLKEKVAEIPELHAVSEFIHFACT 122
Query 121 SEDINNLSHALMLKNGR-EVLVSSMKQILNAIAALATTHAEQPMLSRTHGQTASPTTLGK 179
SEDINNLSHALMLK R EV++ +Q+++ I LA + + P+LSRTHGQ A+P+T+GK
Sbjct 123 SEDINNLSHALMLKTARDEVILPYWRQLIDGIKDLAVQYRDIPLLSRTHGQPATPSTIGK 182
Query 180 EMANVAYRLARQIKQFENVELLGKINGAVGNYNAHLSAYPDIDWAAHSQAFVESLGLTFN 239
EMANVAYR+ RQ +Q VE+LGKINGAVGNYNAH++AYP++DW S+ FV SLG+ +N
Sbjct 183 EMANVAYRMERQYRQLNQVEILGKINGAVGNYNAHIAAYPEVDWHQFSEEFVTSLGIQWN 242
Query 240 PYTTQIEPHDYMAELFDALRRYNTILIDFNRDVWGYISLGYFKQKLKDGEVGSSTMPHKV 299
PYTTQIEPHDY+AELFD + R+NTILIDF+RDVWGYI+L +FKQK GE+GSSTMPHKV
Sbjct 243 PYTTQIEPHDYIAELFDCVARFNTILIDFDRDVWGYIALNHFKQKTIAGEIGSSTMPHKV 302
Query 300 NPIDFENSEGNLGIANAVLGHLGEKLPVSRWQRDLTDSTVLRNMGVGFAQSLIAFDACLK 359
NPIDFENSEGNLG++NAVL HL KLPVSRWQRDLTDSTVLRN+GVG +LIA+ + LK
Sbjct 303 NPIDFENSEGNLGLSNAVLQHLASKLPVSRWQRDLTDSTVLRNLGVGIGYALIAYQSTLK 362
Query 360 GIGKLELNAARLAEDLNQAQEVLAEPIQTVMRRYNVEKPYEKLKALTRGQAMTRDMMVNF 419
G+ KLE+N L ++L+ EVLAEPIQTVMRRY +EKPYEKLK LTRG+ + + M F
Sbjct 363 GVSKLEVNRDHLLDELDHNWEVLAEPIQTVMRRYGIEKPYEKLKELTRGKRVDAEGMKQF 422
Query 420 VNGDELSQVPAEERARLAEMTPASYTGNAADQAKQI 455
++G L P EE+ARL MTPA+Y G A ++
Sbjct 423 IDGLAL---PEEEKARLKAMTPANYIGRAITMVDEL 455
>P0AB89 Adenylosuccinate lyase [Escherichia coli (strain K12)]
Length=456
Score = 586 bits (1511), Expect = 0.0
Identities = 292/456 (64%), Positives = 357/456 (78%), Gaps = 4/456 (1%)
Query 1 MNALTALSPLDGRYASKCDALRPFLSEFGLIHARVTVEVRWLQALSNHAGIIEVAPFSTE 60
+++LTA+SP+DGRY K ALR SE+GL+ RV VEVRWLQ L+ HA I EV F+ +
Sbjct 3 LSSLTAVSPVDGRYGDKVSALRGIFSEYGLLKFRVQVEVRWLQKLAAHAAIKEVPAFAAD 62
Query 61 TNAALDSIVANFSEDDANRIKEIERTTNHDVKAVEYFLKEKIAGLDELKNAGEFIHFACT 120
LD+IVA+FSE+DA RIK IERTTNHDVKAVEYFLKEK+A + EL EFIHFACT
Sbjct 63 AIGYLDAIVASFSEEDAARIKTIERTTNHDVKAVEYFLKEKVAEIPELHAVSEFIHFACT 122
Query 121 SEDINNLSHALMLKNGR-EVLVSSMKQILNAIAALATTHAEQPMLSRTHGQTASPTTLGK 179
SEDINNLSHALMLK R EV++ +Q+++ I LA + + P+LSRTHGQ A+P+T+GK
Sbjct 123 SEDINNLSHALMLKTARDEVILPYWRQLIDGIKDLAVQYRDIPLLSRTHGQPATPSTIGK 182
Query 180 EMANVAYRLARQIKQFENVELLGKINGAVGNYNAHLSAYPDIDWAAHSQAFVESLGLTFN 239
EMANVAYR+ RQ +Q VE+LGKINGAVGNYNAH++AYP++DW S+ FV SLG+ +N
Sbjct 183 EMANVAYRMERQYRQLNQVEILGKINGAVGNYNAHIAAYPEVDWHQFSEEFVTSLGIQWN 242
Query 240 PYTTQIEPHDYMAELFDALRRYNTILIDFNRDVWGYISLGYFKQKLKDGEVGSSTMPHKV 299
PYTTQIEPHDY+AELFD + R+NTILIDF+RDVWGYI+L +FKQK GE+GSSTMPHKV
Sbjct 243 PYTTQIEPHDYIAELFDCVARFNTILIDFDRDVWGYIALNHFKQKTIAGEIGSSTMPHKV 302
Query 300 NPIDFENSEGNLGIANAVLGHLGEKLPVSRWQRDLTDSTVLRNMGVGFAQSLIAFDACLK 359
NPIDFENSEGNLG++NAVL HL KLPVSRWQRDLTDSTVLRN+GVG +LIA+ + LK
Sbjct 303 NPIDFENSEGNLGLSNAVLQHLASKLPVSRWQRDLTDSTVLRNLGVGIGYALIAYQSTLK 362
Query 360 GIGKLELNAARLAEDLNQAQEVLAEPIQTVMRRYNVEKPYEKLKALTRGQAMTRDMMVNF 419
G+ KLE+N L ++L+ EVLAEPIQTVMRRY +EKPYEKLK LTRG+ + + M F
Sbjct 363 GVSKLEVNRDHLLDELDHNWEVLAEPIQTVMRRYGIEKPYEKLKELTRGKRVDAEGMKQF 422
Query 420 VNGDELSQVPAEERARLAEMTPASYTGNAADQAKQI 455
++G L P EE+ARL MTPA+Y G A ++
Sbjct 423 IDGLAL---PEEEKARLKAMTPANYIGRAITMVDEL 455
>P57351 Adenylosuccinate lyase [Buchnera aphidicola subsp. Acyrthosiphon
pisum (strain APS)]
Length=456
Score = 484 bits (1247), Expect = 8e-173
Identities = 232/456 (51%), Positives = 331/456 (73%), Gaps = 4/456 (1%)
Query 1 MNALTALSPLDGRYASKCDALRPFLSEFGLIHARVTVEVRWLQALSNHAGIIEVAPFSTE 60
+ +LTA+SP+DGRY++ LR SEFG + R+ +EV+WL+ + + + I+++ +
Sbjct 3 LTSLTAISPVDGRYSNLTILLRNIFSEFGFLKYRLNIEVQWLKKIISMSQILDINNIEYK 62
Query 61 TNAALDSIVANFSEDDANRIKEIERTTNHDVKAVEYFLKEKIAGLDELKNAGEFIHFACT 120
LDSIV F+E DA IK IE+ TNHD+KA+EYFLK KIA L EF+HF CT
Sbjct 63 EILFLDSIVEEFNEKDAILIKNIEKETNHDIKALEYFLKNKIAQSKNLLTISEFVHFGCT 122
Query 121 SEDINNLSHALMLKNGREVLVSSM-KQILNAIAALATTHAEQPMLSRTHGQTASPTTLGK 179
SEDINN++++LM+K+ R+ ++ + +I++ + + + P+LS THGQ A+P+T+GK
Sbjct 123 SEDINNIAYSLMIKDARDKIILPLWYKIISTLKKMVFKYQHYPLLSLTHGQPATPSTMGK 182
Query 180 EMANVAYRLARQIKQFENVELLGKINGAVGNYNAHLSAYPDIDWAAHSQAFVESLGLTFN 239
E+AN YR+ RQ + +E+LGKING+ GNYNAHL+AYPDI+W S+ F+ S G+ +N
Sbjct 183 EIANFYYRMKRQYIILKKIEILGKINGSTGNYNAHLAAYPDINWHKISKDFITSFGINWN 242
Query 240 PYTTQIEPHDYMAELFDALRRYNTILIDFNRDVWGYISLGYFKQKLKDGEVGSSTMPHKV 299
PYTTQIEPHDY+AE F + +NTILI+FNRD+WGYISL YFKQ+ D E+GSS MPHKV
Sbjct 243 PYTTQIEPHDYIAEFFSCMSLFNTILINFNRDMWGYISLNYFKQRTIDYEIGSSIMPHKV 302
Query 300 NPIDFENSEGNLGIANAVLGHLGEKLPVSRWQRDLTDSTVLRNMGVGFAQSLIAFDACLK 359
NPIDFENSEGNLG++NA++ H+ KLP+SRWQRDL+DSTVLRN+GV + ++IA+++ L
Sbjct 303 NPIDFENSEGNLGLSNALMNHMITKLPISRWQRDLSDSTVLRNIGVAISYAIIAYNSVLS 362
Query 360 GIGKLELNAARLAEDLNQAQEVLAEPIQTVMRRYNVEKPYEKLKALTRGQAMTRDMMVNF 419
GI KLE+N + L ++L++ +L+EPIQT+MRRY ++ YEKLK LTRG+ + R+++ F
Sbjct 363 GINKLEINESELLKNLDKNWSILSEPIQTIMRRYGIKNAYEKLKKLTRGKEINRNVIHTF 422
Query 420 VNGDELSQVPAEERARLAEMTPASYTGNAADQAKQI 455
++ +P EE+ RL MTP +Y G A+ +I
Sbjct 423 ISS---LNIPEEEKKRLKNMTPFNYIGAASQIINEI 455
>Q8K9Q7 Adenylosuccinate lyase [Buchnera aphidicola subsp. Schizaphis
graminum (strain Sg)]
Length=456
Score = 481 bits (1237), Expect = 3e-171
Identities = 237/456 (52%), Positives = 331/456 (73%), Gaps = 4/456 (1%)
Query 1 MNALTALSPLDGRYASKCDALRPFLSEFGLIHARVTVEVRWLQALSNHAGIIEVAPFSTE 60
+N+LTA+SP+DGRY++ LR SEFG + R+ VE++WL+ L N I+E+
Sbjct 3 LNSLTAISPIDGRYSNSTKLLRNIFSEFGFLKYRLYVEIQWLKKLINMHQILEIKKVEKT 62
Query 61 TNAALDSIVANFSEDDANRIKEIERTTNHDVKAVEYFLKEKIAGLDELKNAGEFIHFACT 120
LD+I F+E+DA +K IE+ TNHDVKA+EYFL++K++ +L EF+HF CT
Sbjct 63 DILFLDNIFETFNEEDAISVKNIEKETNHDVKALEYFLRKKLSQSKKLSPFLEFVHFLCT 122
Query 121 SEDINNLSHALMLKNGR-EVLVSSMKQILNAIAALATTHAEQPMLSRTHGQTASPTTLGK 179
SEDINN+++ALM+KN R E+++ K+I+N + + + +LS THGQ A+P+T+GK
Sbjct 123 SEDINNIAYALMIKNARDEIILPLWKKIINFLKNASFQYRNNSLLSLTHGQPATPSTMGK 182
Query 180 EMANVAYRLARQIKQFENVELLGKINGAVGNYNAHLSAYPDIDWAAHSQAFVESLGLTFN 239
EM N YR+ RQ + + +E+LGKING GNYNAHL AYP ++W A S+ F+ SLG+ +N
Sbjct 183 EMVNFYYRMQRQYHKLKKIEILGKINGTTGNYNAHLVAYPKVNWHAVSKEFITSLGIFWN 242
Query 240 PYTTQIEPHDYMAELFDALRRYNTILIDFNRDVWGYISLGYFKQKLKDGEVGSSTMPHKV 299
PYTTQIEPHDY+AELF + +N ILID NRD+WGYISL YFKQKL D E+GSS MPHK+
Sbjct 243 PYTTQIEPHDYIAELFGCVSLFNNILIDSNRDIWGYISLNYFKQKLIDQEIGSSIMPHKI 302
Query 300 NPIDFENSEGNLGIANAVLGHLGEKLPVSRWQRDLTDSTVLRNMGVGFAQSLIAFDACLK 359
NPIDFENSEGNLG++NA++ H+ KLP+SRWQRDL+DSTVLRN+GV FA S+IA+++ L
Sbjct 303 NPIDFENSEGNLGLSNALMNHMINKLPISRWQRDLSDSTVLRNIGVVFAYSIIAYNSVLL 362
Query 360 GIGKLELNAARLAEDLNQAQEVLAEPIQTVMRRYNVEKPYEKLKALTRGQAMTRDMMVNF 419
G KL +N ++L ++L+ VL+E IQTVMRRY +E YEKLK LTRG+ + + + F
Sbjct 363 GTNKLTINTSQLLKNLDNNWSVLSEAIQTVMRRYTIENAYEKLKKLTRGKKIEKVDIHKF 422
Query 420 VNGDELSQVPAEERARLAEMTPASYTGNAADQAKQI 455
+ D+L+ +P E+ RL +++P++Y G A+ +I
Sbjct 423 I--DKLN-IPKIEKERLKKISPSNYIGAASQIIDEI 455
>A5IGB3 Adenylosuccinate lyase [Legionella pneumophila (strain
Corby)]
Length=456
Score = 474 bits (1221), Expect = 7e-169
Identities = 238/454 (52%), Positives = 318/454 (70%), Gaps = 4/454 (1%)
Query 1 MNALTALSPLDGRYASKCDALRPFLSEFGLIHARVTVEVRWLQALSNHAGIIEVAPFSTE 60
+ AL A+SP+DGRY +K AL P+ SEF L + R+ VE++W ++L+ + I EV +
Sbjct 3 LTALNAISPIDGRYVNKTRALSPYFSEFALTYYRLMVEIKWFESLAANDTIPEVPALDNK 62
Query 61 TNAALDSIVANFSEDDANRIKEIERTTNHDVKAVEYFLKEKIAGLDELKNAGEFIHFACT 120
L +++NF+E +A +IKE E+ TNHDVKAVEY+LK+K ++LK+ FIHFACT
Sbjct 63 ARKFLSDLISNFNESEAEKIKEFEKQTNHDVKAVEYYLKDKFQENEQLKSCVAFIHFACT 122
Query 121 SEDINNLSHALMLKNG-REVLVSSMKQILNAIAALATTHAEQPMLSRTHGQTASPTTLGK 179
SEDINNL++ALM+K +V+ ++ +I+ +I L HA+ MLSRTHGQ A+PTT+GK
Sbjct 123 SEDINNLAYALMIKQAIAQVIQPTIAEIMGSITLLGKQHADVAMLSRTHGQPATPTTMGK 182
Query 180 EMANVAYRLARQIKQFENVELLGKINGAVGNYNAHLSAYPDIDWAAHSQAFVESLGLTFN 239
E+ N RL R +Q V + K NGAVGNYNAH++AYP++DW H FV SLGL+FN
Sbjct 183 ELVNFVARLKRPQQQLAEVLIPAKFNGAVGNYNAHVAAYPEVDWRKHCANFVTSLGLSFN 242
Query 240 PYTTQIEPHDYMAELFDALRRYNTILIDFNRDVWGYISLGYFKQKLKDGEVGSSTMPHKV 299
YTTQIEPHD +AE+ + R N IL+D+ +D+W YISLGYFKQK EVGSSTMPHKV
Sbjct 243 AYTTQIEPHDGIAEVSQIMVRINNILLDYTQDIWSYISLGYFKQKTIAEEVGSSTMPHKV 302
Query 300 NPIDFENSEGNLGIANAVLGHLGEKLPVSRWQRDLTDSTVLRNMGVGFAQSLIAFDACLK 359
NPIDFEN+EGNLG++NA+ H KL SR QRDL+DSTVLRN+GV F+ SLIA+ + K
Sbjct 303 NPIDFENAEGNLGLSNALFIHFANKLTQSRMQRDLSDSTVLRNLGVAFSYSLIAYHSVAK 362
Query 360 GIGKLELNAARLAEDLNQAQEVLAEPIQTVMRRYNVEKPYEKLKALTRGQAMTRDMMVNF 419
G KL++N + L +DL++ EVLAE IQTVMRRYN YE+LK LTRGQ + + + F
Sbjct 363 GNDKLQINKSALQKDLSENWEVLAEAIQTVMRRYNEPNAYEQLKELTRGQMIDAENLKKF 422
Query 420 VNGDELSQVPAEERARLAEMTPASYTGNAADQAK 453
+ + +P E +A L ++TP +YTG A K
Sbjct 423 I---KTLSIPEEAKAELMKLTPETYTGLATQLVK 453
>Q5ZXD1 Adenylosuccinate lyase [Legionella pneumophila subsp.
pneumophila (strain Philadelphia 1 / ATCC 33152 / DSM 7513)]
Length=456
Score = 473 bits (1217), Expect = 3e-168
Identities = 237/454 (52%), Positives = 318/454 (70%), Gaps = 4/454 (1%)
Query 1 MNALTALSPLDGRYASKCDALRPFLSEFGLIHARVTVEVRWLQALSNHAGIIEVAPFSTE 60
+ AL A+SP+DGRY +K AL P+ SEF L + R+ VE++W ++L+ + I EV +
Sbjct 3 LTALNAISPIDGRYVNKTRALSPYFSEFALTYYRLMVEIKWFESLAANDTIPEVPALDNK 62
Query 61 TNAALDSIVANFSEDDANRIKEIERTTNHDVKAVEYFLKEKIAGLDELKNAGEFIHFACT 120
L +++NF+E +A +IKE E+ TNHDVKAVEY+L++K ++LK+ FIHFACT
Sbjct 63 ARKFLSDLISNFNESEAEKIKEFEKQTNHDVKAVEYYLQDKFQENEQLKSCVAFIHFACT 122
Query 121 SEDINNLSHALMLKNG-REVLVSSMKQILNAIAALATTHAEQPMLSRTHGQTASPTTLGK 179
SEDINNL++ALM+K +V+ ++ +I+ +I L HA+ MLSRTHGQ A+PTT+GK
Sbjct 123 SEDINNLAYALMIKQAIAQVIQPTIAEIMGSITLLGKQHADVAMLSRTHGQPATPTTMGK 182
Query 180 EMANVAYRLARQIKQFENVELLGKINGAVGNYNAHLSAYPDIDWAAHSQAFVESLGLTFN 239
E+ N RL R +Q V + K NGAVGNYNAH++AYP++DW H FV SLGL+FN
Sbjct 183 ELVNFVARLKRPQQQLAEVLIPAKFNGAVGNYNAHVAAYPEVDWRKHCANFVTSLGLSFN 242
Query 240 PYTTQIEPHDYMAELFDALRRYNTILIDFNRDVWGYISLGYFKQKLKDGEVGSSTMPHKV 299
YTTQIEPHD +AE+ + R N IL+D+ +D+W YISLGYFKQK EVGSSTMPHKV
Sbjct 243 AYTTQIEPHDGIAEVSQIMVRINNILLDYTQDIWSYISLGYFKQKTIAEEVGSSTMPHKV 302
Query 300 NPIDFENSEGNLGIANAVLGHLGEKLPVSRWQRDLTDSTVLRNMGVGFAQSLIAFDACLK 359
NPIDFEN+EGNLG++NA+ H KL SR QRDL+DSTVLRN+GV F+ SLIA+ + K
Sbjct 303 NPIDFENAEGNLGLSNALFIHFANKLTQSRMQRDLSDSTVLRNLGVAFSYSLIAYHSVAK 362
Query 360 GIGKLELNAARLAEDLNQAQEVLAEPIQTVMRRYNVEKPYEKLKALTRGQAMTRDMMVNF 419
G KL++N + L +DL++ EVLAE IQTVMRRYN YE+LK LTRGQ + + + F
Sbjct 363 GNDKLQINKSALQKDLSENWEVLAEAIQTVMRRYNEPNAYEQLKELTRGQMIDAENLKKF 422
Query 420 VNGDELSQVPAEERARLAEMTPASYTGNAADQAK 453
+ + +P E +A L ++TP +YTG A K
Sbjct 423 I---KTLSIPEEAKAELMKLTPETYTGLATQLVK 453
>Q89AM3 Adenylosuccinate lyase [Buchnera aphidicola subsp. Baizongia
pistaciae (strain Bp)]
Length=460
Score = 473 bits (1216), Expect = 4e-168
Identities = 237/455 (52%), Positives = 326/455 (72%), Gaps = 6/455 (1%)
Query 4 LTALSPLDGRYASKCDALRPFLSEFGLIHARVTVEVRWLQALSNHAGIIEVAPFSTETNA 63
L A+SP+DGRY+SK LR SE+ + RVT+E+ WL+ +S V ++ +
Sbjct 6 LFAISPIDGRYSSKVIKLRNIFSEYAFLKFRVTIELLWLKKISLLQEFKIV--YNKDVLN 63
Query 64 ALDSIVANFSEDDANRIKEIERTTNHDVKAVEYFLKEKIAGLDELKNAGEFIHFACTSED 123
LD I+ NFS+ DA IK +E+ TNHDVK++EYFL++KI + +HF CTSED
Sbjct 64 CLDRIIDNFSKKDALEIKILEKKTNHDVKSIEYFLQKKIFKCLGNHDILGLVHFGCTSED 123
Query 124 INNLSHALMLK-NGREVLVSSMKQILNAIAALATTHAEQPMLSRTHGQTASPTTLGKEMA 182
INNL++ALMLK + R++++ +I+ I +A H PMLSRTHGQ A+P+T+GKE+
Sbjct 124 INNLAYALMLKVSRRDIILPLWNKIIFEIKKIALLHHNVPMLSRTHGQPATPSTIGKELI 183
Query 183 NVAYRLARQIKQFENVELLGKINGAVGNYNAHLSAYPDIDWAAHSQAFVESLGLTFNPYT 242
N AYRL RQ+KQF+N+E+LGKING+ GNYNA ++ +DW SQ FV SLGL +NPYT
Sbjct 184 NFAYRLERQLKQFKNIEILGKINGSTGNYNALHFSHSSVDWHKISQEFVTSLGLFWNPYT 243
Query 243 TQIEPHDYMAELFDALRRYNTILIDFNRDVWGYISLGYFKQKLKDGEVGSSTMPHKVNPI 302
TQIEPHD+++E F L R NTILI+FNRD+WGYISL YF Q K E+GSS MPHK+NPI
Sbjct 244 TQIEPHDFISEFFSCLARVNTILINFNRDIWGYISLQYFNQTPKLDEIGSSVMPHKINPI 303
Query 303 DFENSEGNLGIANAVLGHLGEKLPVSRWQRDLTDSTVLRNMGVGFAQSLIAFDACLKGIG 362
DFENSEGNLG++NA++ HL EKLP+SRWQRDL+DSTVLRN+G A S+IA+D+ + G+
Sbjct 304 DFENSEGNLGLSNAIISHLIEKLPISRWQRDLSDSTVLRNVGTVIAYSIIAYDSIILGLK 363
Query 363 KLELNAARLAEDLNQAQEVLAEPIQTVMRRYNVEKPYEKLKALTRGQAMTRDMMVNFVNG 422
KL++N +RL +DLN E+LAEPIQTVMR+Y + Y +LK +TRG+ +T D+++ +VN
Sbjct 364 KLKVNTSRLLQDLNHHWEILAEPIQTVMRKYGINDTYNELKNITRGKRVTSDIILKYVNS 423
Query 423 DELSQVPAEERARLAEMTPASYTGNAADQAKQIND 457
++P E+ +L ++TP +Y G ++ K N+
Sbjct 424 ---LKIPRNEKEKLLQLTPENYLGLSSKLVKIFNN 455
>Q54J34 Adenylosuccinate lyase [Dictyostelium discoideum]
Length=466
Score = 379 bits (973), Expect = 3e-131
Identities = 220/463 (48%), Positives = 295/463 (64%), Gaps = 19/463 (4%)
Query 1 MNALTALSPLDGRYASKCDALRPFLSEFGLIHARVTVEVRWLQALSNHAGIIEVAPFST- 59
+N LTA+SP+DGRY + L + SE+ LI RV VE+ + LS + E+ P +
Sbjct 9 LNNLTAISPIDGRYWGQVQVLSEYFSEYALIKYRVQVEIEYFIELSK---LSELKPLNAV 65
Query 60 ---ETNAALDSIVANFSEDDANRIKEIERTTNHDVKAVEYFLKEKI-AGLDELKNAGEFI 115
+ + L I F E DA +IK+IE+TTNHD+KAVEYF+KEK+ L + EFI
Sbjct 66 NKEDDHKKLRDIYLQFKESDAQKIKQIEKTTNHDIKAVEYFIKEKMHTELQYSEVVTEFI 125
Query 116 HFACTSEDINNLSHAL-MLKNGREVLVSSMKQ-ILNAIAALATTHAEQPMLSRTHGQTAS 173
HF TS+DINN + L ++++ +VL+ +KQ IL + A PML+RTHGQ A+
Sbjct 126 HFGLTSQDINNTAIPLSIVESVEKVLIPQLKQSILEPLRQFAQQWKSIPMLARTHGQPAT 185
Query 174 PTTLGKEMANVAYRLARQIKQFE-NVELLGKINGAVGNYNAHLSAYPDIDWAAHSQAFVE 232
PTT+GKE+ RL QI E +V K GA GN NAH +YP IDW S+ FV+
Sbjct 186 PTTVGKELMVFIERLENQINHLEQSVPHTCKFGGATGNLNAHKVSYPAIDWVVFSEKFVK 245
Query 233 SL--GLTFNPYTTQIEPHDYMAELFDALRRYNTILIDFNRDVWGYISLGYFKQKLKDGEV 290
L L +TTQIE +D +A L DA +R NTILID RD+W YIS+ YF QKL GEV
Sbjct 246 VLHPSLKRMRFTTQIEHYDNVASLLDAFKRINTILIDLCRDIWTYISMEYFNQKLVKGEV 305
Query 291 GSSTMPHKVNPIDFENSEGNLGIANAVLGHLGEKLPVSRWQRDLTDSTVLRNMGVGFAQS 350
GSSTMPHKVNPIDFEN+EGN+G+ANA+ HL KLP+SR QRDLTDSTVLR++GV F+ S
Sbjct 306 GSSTMPHKVNPIDFENAEGNMGVANALYEHLSAKLPISRLQRDLTDSTVLRSIGVPFSHS 365
Query 351 LIAFDACLKGIGKLELNAARLAEDLNQAQEVLAEPIQTVMRRYNVEKPYEKLKALTR--- 407
+++F + +G+ KL LN A +A+DL+ V++E IQT++RR KPYE LK LTR
Sbjct 366 ILSFKSIQRGLSKLVLNEANIAKDLDANWAVVSEAIQTILRREGFPKPYEALKELTRVSG 425
Query 408 GQAMTRDMMVNFVNGDELSQVPAEERARLAEMTPASYTGNAAD 450
+ +T + F+ D LS +P + ++ L +TP +Y G D
Sbjct 426 SKKITESDIQTFI--DSLS-IPDDIKSELKLITPFNYIGIIPD 465
>P12047 Adenylosuccinate lyase [Bacillus subtilis (strain 168)]
Length=431
Score = 109 bits (273), Expect = 3e-29
Identities = 96/341 (28%), Positives = 159/341 (47%), Gaps = 32/341 (9%)
Query 76 DANRIKEIERTTNHDVKAVEYFLKEKIAGLDELKNAGEFIHFACTSEDINNLSHALMLKN 135
D NRI EIE+ T HDV A + E + +E K ++H+ TS D+ + + + +LK
Sbjct 55 DINRILEIEKDTRHDVVAFTRAVSESLG--EERK----WVHYGLTSTDVVDTALSYLLKQ 108
Query 136 GREVLVSSMKQILNAIAALATTHAEQPMLSRTHGQTASPTTLGKEMANVAYRLARQIKQF 195
++L+ +++ ++ I A H M+ RTHG A PTT G ++A + R +++F
Sbjct 109 ANDILLKDLERFVDIIKEKAKEHKYTVMMGRTHGVHAEPTTFGLKLALWHEEMKRNLERF 168
Query 196 ENVEL---LGKINGAVGNYNAHLSAYPDIDWAAHSQAFVESLGLTFNPYTTQIEPHDYMA 252
+ + +GKI+GAVG Y A++ + + Q E LGL P +TQ D A
Sbjct 169 KQAKAGIEVGKISGAVGTY-ANIDPFVE-------QYVCEKLGLKAAPISTQTLQRDRHA 220
Query 253 ELFDALRRYNTILIDFNRDVWGY--ISLGYFKQKLKDGEVGSSTMPHKVNPIDFENSEGN 310
+ L T + F ++ G ++ G+ GSS MPHK NPI EN G
Sbjct 221 DYMATLALIATSIEKFAVEIRGLQKSETREVEEFFAKGQKGSSAMPHKRNPIGSENMTGM 280
Query 311 LGIANAVLGHLGEKLPVSRW-QRDLTDST----VLRNMGVGFAQSLIAFDACLKGIGKLE 365
+ + E +P+ W +RD++ S+ +L + + L F +K +
Sbjct 281 ARVIRGYMMTAYENVPL--WHERDISHSSAERIILPDATIALNYMLNRFSNIVKNLTVFP 338
Query 366 LNAARLAE---DLNQAQEVLAEPIQTVMRRYNVEKPYEKLK 403
N R + L +Q VL I T + R E+ Y+ ++
Sbjct 339 ENMKRNMDRTLGLIYSQRVLLALIDTGLTR---EEAYDTVQ 376
Score = 18.9 bits (37), Expect = 6.8
Identities = 14/56 (25%), Positives = 28/56 (50%), Gaps = 10/56 (18%)
Query 52 IEVAPFSTET--------NAALDSIVANFSEDDANRIKEIERTTNHDVKAVEYFLK 99
++ AP ST+T A +++A E A I+ ++++ +V+ E+F K
Sbjct 204 LKAAPISTQTLQRDRHADYMATLALIATSIEKFAVEIRGLQKSETREVE--EFFAK 257
>Q9X0I0 Adenylosuccinate lyase [Thermotoga maritima (strain ATCC
43589 / DSM 3109 / JCM 10099 / NBRC 100826 / MSB8)]
Length=431
Score = 99.0 bits (245), Expect = 1e-25
Identities = 81/291 (28%), Positives = 136/291 (47%), Gaps = 26/291 (9%)
Query 69 VANFSEDDANRIKEIERTTNHDVKAVEYFLKEKIAGLDELKNAGEFIHFACTSEDINNLS 128
+ N ++ D K+IE TNHDV A E I + + F H+ TS D+ + +
Sbjct 48 IRNNAKIDVELFKKIEEKTNHDVVA----FVEGIGSM--IGEDSRFFHYGLTSSDVLDTA 101
Query 129 HALMLKNGREVLVSSMKQILNAIAALATTHAEQPMLSRTHGQTASPTTLGKEMANVAYRL 188
++L L ++L+ S+K+ + + +A + P + RTHG A PT+ G ++ +
Sbjct 102 NSLALVEAGKILLESLKEFCDVLWEVANRYKHTPTIGRTHGVHAEPTSFGLKVLGWYSEM 161
Query 189 ARQIKQFENV---ELLGKINGAVGNYNAHLSAYPDIDWAAHSQAFVESLGLTFNPYTTQI 245
R +++ E GKI+GAVGNY + P+++ A S LGL P +TQ+
Sbjct 162 KRNVQRLERAIEEVSYGKISGAVGNY---ANVPPEVEEKALSY-----LGLKPEPVSTQV 213
Query 246 EPHD----YMAELFDALRRYNTILIDFNRDVWGYISLGYFKQKLKDGEVGSSTMPHKVNP 301
P D Y++ L I ++ + ++ + G+ GSS MPHK NP
Sbjct 214 VPRDRHAFYLSTLAIVAAGIERIAVEIRH--LQRTEVLEVEEPFRKGQRGSSAMPHKKNP 271
Query 302 IDFENSEGNLGIANAVLGHLGEKLPVSRW-QRDLTDSTVLRNMGVGFAQSL 351
I E G + A + E ++ W +RD++ S+V R + Q+L
Sbjct 272 ITCERLTGLSRMMRAYVDPSLEN--IALWHERDISHSSVERYVFPDATQTL 320
>Q7A0G9 Adenylosuccinate lyase [Staphylococcus aureus (strain
MW2)]
Length=431
Score = 92.8 bits (229), Expect = 2e-23
Identities = 75/274 (27%), Positives = 130/274 (47%), Gaps = 22/274 (8%)
Query 76 DANRIKEIERTTNHDVKAVEYFLKEKIAGLDELKNAGEFIHFACTSEDINNLSHALMLKN 135
+ R +EIE+ T HDV A + E + +E K ++H+ TS D+ + + + ++K
Sbjct 55 NVERAQEIEQETRHDVVAFTRQVSETLG--EERK----WVHYGLTSTDVVDTALSFVIKQ 108
Query 136 GREVLVSSMKQILNAIAALATTHAEQPMLSRTHGQTASPTTLGKEMANVAYRLARQIKQF 195
+++ +++ ++ +A A + M+ RTHG A PTT G +MA + R +++F
Sbjct 109 ANDIIEKDLERFIDVLAEKAKNYKYTLMMGRTHGVHAEPTTFGVKMALWYTEMQRNLQRF 168
Query 196 ENVE---LLGKINGAVGNYNAHLSAYPDIDWAAHSQAFVESLGLTFNPYTTQIEPHDYMA 252
+ V +GK++GAVG + + P+I+ + LG+ P +TQ D A
Sbjct 169 KQVREEIEVGKMSGAVGTF---ANIPPEIE-----SYVCKHLGIGTAPVSTQTLQRDRHA 220
Query 253 ELFDALRRYNTILIDFNRDVWGY--ISLGYFKQKLKDGEVGSSTMPHKVNPIDFENSEGN 310
L T L F ++ ++ G+ GSS MPHK NPI EN G
Sbjct 221 YYIATLALIATSLEKFAVEIRNLQKTETREVEEAFAKGQKGSSAMPHKRNPIGSENITGI 280
Query 311 LGIANAVLGHLGEKLPVSRW-QRDLTDSTVLRNM 343
+ + E +P+ W +RD++ S+ R M
Sbjct 281 SRVIRGYITTAYENVPL--WHERDISHSSAERIM 312
>P32427 3-carboxy-cis,cis-muconate cycloisomerase [Pseudomonas
putida]
Length=422
Score = 73.6 bits (179), Expect = 3e-17
Identities = 97/389 (25%), Positives = 158/389 (41%), Gaps = 41/389 (11%)
Query 20 ALRPFLSEFGLIHARVTVEVRWLQALSNHAGIIEVAPFSTETNAALDSIVANFSEDDANR 79
A+R S+ G + + E AL+ + P S AA+++ D
Sbjct 14 AMREIFSDRGRLQGMLDFEA----ALARAEAAAGLVPHSAV--AAIEAACKAERYDVGAL 67
Query 80 IKEIERTTNHDVKAVEYFLKEKIAGLDELKNAGEFIHFACTSEDINNLSHALMLKNGREV 139
I N + V+ K +G+ E A ++H TS+D + L L++ ++
Sbjct 68 ANAIATAGNSAIPLVKALGKVIASGVPE---AERYVHLGATSQDAMDTGLVLQLRDALDL 124
Query 140 LVSSMKQILNAIAALATTHAEQPMLSRTHGQTASPTTLGKEMANVAYRLARQIKQFENVE 199
+ + + ++ + ++ A HA+ PM+ RT Q A+P TLG ++A V L R ++ + +
Sbjct 125 IEADLGKLADTLSQQALKHADTPMVGRTWLQHATPVTLGMKLAGVLGALTRHRQRLQELG 184
Query 200 ---LLGKINGAVGNYNAHLSAYPDIDWAAHSQAFVESLGLTFNPYTTQIEPHDYMAELFD 256
GA G+ A S + A Q L L P+ TQ D + E
Sbjct 185 PPCWCCSSGGASGSLAALGSKAMPVAEALAEQL---KLSLPEQPWHTQ---RDRLVEFAS 238
Query 257 ALRRYNTILIDFNRDV--WGYISLGYFKQKLKDGEVGSSTMPHKVNPIDFENSEGNLGIA 314
L L F RDV G + G+ GSSTMPHK NP+ + +G A
Sbjct 239 VLGLVAGSLGKFGRDVSLLMQTEAGEVFEPSAPGKGGSSTMPHKRNPV---GAAVLIGAA 295
Query 315 NAVLGHLGEKLPVSRWQRDLTDSTVLRNMGVGFAQSLIAFDACLKGIGKL---------- 364
V G + + + R++G+ A+ D C G L
Sbjct 296 TRVPGLVSTLFAAMPQEHE-------RSLGLWHAEWETLPDICCLVSGALRQAQVIAEGI 348
Query 365 ELNAARLAEDLNQAQE-VLAEPIQTVMRR 392
E++AAR+ +L+ Q VLAE + V+ R
Sbjct 349 EVDAARMRRNLDLTQGLVLAEAVSIVLAR 377
>P21265 Adenylosuccinate lyase [Gallus gallus]
Length=485
Score = 63.9 bits (154), Expect = 5e-14
Identities = 70/312 (22%), Positives = 126/312 (40%), Gaps = 31/312 (10%)
Query 61 TNAALDSIVANFSEDDANRIKEIERTTNHDVKAVEYFLKEKIAGLDELKNAGEFIHFACT 120
T+ + + AN D E E+ HDV A + A IH T
Sbjct 59 TDEQIKEMEANLDNIDFKMAAEEEKKLRHDVMAHVHTFAHCCP------KAAAIIHLGAT 112
Query 121 SEDINNLSHALMLKNGREVLVSSMKQILNAIAALATTHAEQPMLSRTHGQTASPTTLGKE 180
S + + + ++L++G +L+ + ++++ +A A THA+ P L TH Q A TT+GK
Sbjct 113 SCYVGDNTDLIVLRDGFNLLLPKLARVISRLADFAETHADLPTLGFTHYQPAQLTTVGKR 172
Query 181 MANVAYRLARQIKQFENVELLGKINGAVGN----------YNAHLSAYPDIDWAAHSQA- 229
L ++ E + G G + S ++D ++A
Sbjct 173 CCLWIQDLCMDLQNLERARDDLRFRGVKGTTGTQASFLQLFEGDHSKVEELDRLVTAKAG 232
Query 230 FVESLGLTFNPYTTQIEPHDYMAELFDALRRYNTILIDFNRDVWGYISLGYFKQKLKDGE 289
F S +T Y+ +++ E+ L + D+ +L ++ + +
Sbjct 233 FKRSYMVTGQTYSRKVD-----IEVLSVLASLGASVHKICTDIRLLANLKEIEEPFEKDQ 287
Query 290 VGSSTMPHKVNPIDFENSEGNLGIANAVLGHLGEKL---PVSRWQRDLTDSTVLRNMGVG 346
+GSS MP+K NP+ SE +A ++ + + L V ++R L DS N V
Sbjct 288 IGSSAMPYKRNPM---RSERCCSLARHLMTLVLDPLQTASVQWFERTLDDSA---NRRVC 341
Query 347 FAQSLIAFDACL 358
A++ + D L
Sbjct 342 LAEAFLTADIIL 353
Score = 18.5 bits (36), Expect = 9.1
Identities = 7/39 (18%), Positives = 18/39 (46%), Gaps = 0/39 (0%)
Query 363 KLELNAARLAEDLNQAQEVLAEPIQTVMRRYNVEKPYEK 401
K+++ + L + + I+ + +E+P+EK
Sbjct 247 KVDIEVLSVLASLGASVHKICTDIRLLANLKEIEEPFEK 285
>O31385 3-carboxy-cis,cis-muconate cycloisomerase [Bradyrhizobium
diazoefficiens (strain JCM 10833 / BCRC 13528 / IAM 13628
/ NBRC 14792 / USDA 110)]
Length=451
Score = 58.2 bits (139), Expect = 3e-12
Identities = 56/198 (28%), Positives = 87/198 (44%), Gaps = 13/198 (7%)
Query 111 AGEFIHFACTSEDINNLSHALMLKNGREVLVSSMKQILNAIAALATTHAEQPMLSRTHGQ 170
A ++H+ TS+D+ + + L L+ + L + + + + AALA H M++RT Q
Sbjct 99 AARYVHWGATSQDVIDTATMLTLRAAIDALDADLSRAIKGFAALARNHRNTAMVARTWLQ 158
Query 171 TASPTTLGKEMANVAYRLAR---QIKQFENVELLGKINGAVGNYNAHLSAYPDIDWAAHS 227
A P G + A A LAR ++++ L + GA G L+A D
Sbjct 159 HALPMPFGLKAAEYAASLARARCRLRRLSRDGLALQFGGAAGT----LAALGDKGLVVAE 214
Query 228 QAFVE-SLGLTFNPYTTQIEPHDYMAELFDALRRYNTILIDFNRDVWGYISLGYFK--QK 284
+ E +L L P+ T D +AE AL RDV + + +
Sbjct 215 RLAQELNLPLPEAPWHTH---RDRIAEAASALAILAGSCGKIARDVSLMMQTDVAEAFEP 271
Query 285 LKDGEVGSSTMPHKVNPI 302
+G GSSTMPHK NP+
Sbjct 272 AGEGRGGSSTMPHKRNPV 289
>P07343 Fumarate hydratase class II [Bacillus subtilis (strain
168)]
Length=462
Score = 50.8 bits (120), Expect = 7e-10
Identities = 59/232 (25%), Positives = 99/232 (43%), Gaps = 30/232 (13%)
Query 109 KNAGEFIHFACTSEDINNLS----------HALMLKNGREVLVSSMKQILNAIAALATTH 158
KN+ + IH ++D+N H + E LV ++ Q+ N + A +
Sbjct 120 KNSDQTIH---PNDDVNRSQSSNDTFPTAMHVAAVLAVYEQLVPALDQLRNTLDEKAKAY 176
Query 159 AEQPMLSRTHGQTASPTTLGKEMANVAYRLARQ----IKQFENVELLGKINGAVGNYNAH 214
+ + RTH Q A+P TLG+E++ + L R ++ + + L AVG
Sbjct 177 NDIVKIGRTHLQDATPLTLGQEISGWVHMLDRSKEMILEATDKMRALAIGGTAVG---TG 233
Query 215 LSAYPDIDWAAHSQAFVESLGLTFNPYTTQ---IEPHDYMAELFDALRRYNTILIDFNRD 271
++A+P+ S+ + G TF+ + + HD + AL+ L+ D
Sbjct 234 INAHPEFGELV-SEEITKLTGQTFSSSPNKFHALTSHDEITYAHGALKALAADLMKIAND 292
Query 272 VWGYIS---LGYFKQKLKDGEVGSSTMPHKVNPIDFENSEGNLGIANAVLGH 320
V S G + + + E GSS MP KVNP SE IA ++G+
Sbjct 293 VRWLASGPRCGIGEIVIPENEPGSSIMPGKVNP---TQSEALTMIAAQIMGN 341
>P05042 Fumarate hydratase class II [Escherichia coli (strain
K12)]
Length=467
Score = 47.0 bits (110), Expect = 1e-08
Identities = 52/219 (24%), Positives = 93/219 (42%), Gaps = 23/219 (11%)
Query 102 IAGLDELKNAGEFIHFACTSEDI-NNLSHALMLKNGREVLVSSMKQILNAIAALATTHAE 160
+ G++ + + ++ + +S D+ H L R+ L+ +K + + + A+
Sbjct 121 VRGMERKVHPNDDVNKSQSSNDVFPTAMHVAALLALRKQLIPQLKTLTQTLNEKSRAFAD 180
Query 161 QPMLSRTHGQTASPTTLGKEMANVAYRLARQIKQFE----NVELLGKINGAVGNYNAHLS 216
+ RTH Q A+P TLG+E++ L +K E +V L AVG L+
Sbjct 181 IVKIGRTHLQDATPLTLGQEISGWVAMLEHNLKHIEYSLPHVAELALGGTAVG---TGLN 237
Query 217 AYPDIDWAAHSQAFVESLG-LTFNPYTT------QIEPHDYMAELFDALRRYNTILIDFN 269
+P+ +++ + L +T P+ T + D + + AL+ L+
Sbjct 238 THPE-----YARRVADELAVITCAPFVTAPNKFEALATCDALVQAHGALKGLAASLMKIA 292
Query 270 RDVWGYIS---LGYFKQKLKDGEVGSSTMPHKVNPIDFE 305
DV S G + + + E GSS MP KVNP E
Sbjct 293 NDVRWLASGPRCGIGEISIPENEPGSSIMPGKVNPTQCE 331
Lambda K H a alpha
0.318 0.133 0.379 0.792 4.96
Gapped
Lambda K H a alpha sigma
0.267 0.0410 0.140 1.90 42.6 43.6
Effective search space used: 3117230
Database: 23f3b80c130b12dd5c694644082d0d2d.SwissProt.fasta
Posted date: May 17, 2024 7:33 AM
Number of letters in database: 8,610
Number of sequences in database: 19
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Neighboring words threshold: 11
Window for multiple hits: 40
Loading
Data ...
