BLASTP 2.12.0+


Reference: Stephen F. Altschul, Thomas L. Madden, Alejandro A.
Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J.
Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of
protein database search programs", Nucleic Acids Res. 25:3389-3402.


Reference for composition-based statistics: Alejandro A. Schaffer,
L. Aravind, Thomas L. Madden, Sergei Shavirin, John L. Spouge, Yuri
I. Wolf, Eugene V. Koonin, and Stephen F. Altschul (2001),
"Improving the accuracy of PSI-BLAST protein database searches with
composition-based statistics and other refinements", Nucleic Acids
Res. 29:2994-3005.



Database: 813426bc9558b8ef5aa36fa3c355033c.SwissProt.fasta
           12 sequences; 7,051 total letters



Query= ACIAD1276

Length=495
                                                                      Score     E
Sequences producing significant alignments:                          (Bits)  Value

Q797A7 Methylthioribose transporter [Bacillus subtilis (strain 168)]  357     2e-122
O07576 Branched-chain amino acid permease BcaP [Bacillus subtilis...  352     3e-120
Q8W4K3 Cationic amino acid transporter 4, vacuolar [Arabidopsis t...  233     4e-73 
Q9C5D6 Cationic amino acid transporter 9, chloroplastic [Arabidop...  230     3e-72 
Q9ASS7 Cationic amino acid transporter 2, vacuolar [Arabidopsis t...  231     6e-72 
Q8GYB4 Cationic amino acid transporter 3, mitochondrial [Arabidop...  216     2e-66 
O43246 Cationic amino acid transporter 4 [Homo sapiens]               215     7e-66 
Q8BLQ7 Cationic amino acid transporter 4 [Mus musculus]               208     2e-63 
Q84MA5 Cationic amino acid transporter 1 [Arabidopsis thaliana]       206     4e-63 
Q6DCE8 Cationic amino acid transporter 2 [Xenopus laevis]             201     1e-60 
O64759 Cationic amino acid transporter 5 [Arabidopsis thaliana]       199     1e-60 
P18581 Cationic amino acid transporter 2 [Mus musculus]               197     3e-59 


>Q797A7 Methylthioribose transporter [Bacillus subtilis (strain 
168)]
Length=461

 Score = 357 bits (916),  Expect = 2e-122
 Identities = 195/470 (41%), Positives = 281/470 (60%), Gaps = 16/470 (3%)

Query  11   LLRRKPINFLVQETQQGGKTLKRSLTLFQLTMFGVGATIGTGIFFVLSEQVPV-AGPAVL  69
            L R+KP+  L    Q   K+L R+L+ F LT+ G+G  IGTGIF +        AGPA++
Sbjct  4    LFRKKPLETL--SAQSKSKSLARTLSAFDLTLLGIGCVIGTGIFVITGTVAATGAGPALI  61

Query  70   ISFILAGITAGLTALCYAELSSMIPASGSSYSYAYATLGEGVAFLVAACLILEYGVSAAA  129
            ISFILAG+   L A CYAE SS IP SGS YSY+Y TLGE +AFL+   L+LEY ++ +A
Sbjct  62   ISFILAGLACALAAFCYAEFSSSIPISGSVYSYSYVTLGELLAFLIGWDLMLEYVIALSA  121

Query  130  VAIGWSEYLNNLIHNVFGVHLPNWLLSAPFVADGYKLHLGGTGLINLPAAILVFLCCMLL  189
            VA GWS Y  +L+   F +H+P  L  AP    G         + NLPAA+++ L   ++
Sbjct  122  VATGWSSYFQSLLAG-FNLHIPAALTGAPGSMAG--------AVFNLPAAVIILLITAIV  172

Query  190  MRGVTESARINAVMVLIKLCVLILFISIAATAFNAEHLTPFSPHGFAGISAAAGSIFFTF  249
             RGV ES R N V+VL+K+ +++LFI +       ++ +PF P G  G+  +A ++FF +
Sbjct  173  SRGVKESTRFNNVIVLMKIAIILLFIIVGIGYVKPDNWSPFMPFGMKGVILSAATVFFAY  232

Query  250  IGLDAVSTAGEEVENPRRNLPLAIISALFVVIIFYILVALTALGAQEQG-LFKGQQAGLA  308
            +G DAVS A EEV+NP++N+P+ IISAL V  + YI V+L   G      L  G     A
Sbjct  233  LGFDAVSNASEEVKNPQKNMPVGIISALAVCTVLYIAVSLVLTGMMPYAKLNVGDPVSFA  292

Query  309  VILQEITGSTWPAIILAAGAVISVFSITLVVLYGQTRILFAMSRDGLAPKIFHRVSTQTL  368
            +   +  G    A I++ GA+I + ++ L +LY Q R+ FAMSRDGL P +F +V     
Sbjct  293  L---KFVGQDAVAGIISVGAIIGITTVMLALLYAQVRLTFAMSRDGLLPGLFAKVHPSFK  349

Query  369  TPNANTLIVAVIVSIIAGFVPADVLWDLTSMGTLIAFTVVSIGVLVLRYRMPDAPRGFKV  428
            TP  NT +  ++ + IAGF+    L  L +MGTL AFTV+SI V+VLR + P+    F+V
Sbjct  350  TPFRNTWLTGIVAAGIAGFINLGTLAHLVNMGTLAAFTVISIAVIVLRKKHPEIKASFRV  409

Query  429  PFFPALPVLSICACLYLISSLSAIVYVIAAIWAVIAATYYFSCASKNSVL  478
            PF P +P++S   CL+ + SL  + ++   IW  +    YF  + K+S+L
Sbjct  410  PFVPVVPIISAGICLWFMYSLPGVTWLSFVIWIAVGTLVYFLYSRKHSLL  459


>O07576 Branched-chain amino acid permease BcaP [Bacillus subtilis 
(strain 168)]
Length=465

 Score = 352 bits (902),  Expect = 3e-120
 Identities = 193/468 (41%), Positives = 278/468 (59%), Gaps = 9/468 (2%)

Query  11   LLRRKPINFLVQETQQGGKTLKRSLTLFQLTMFGVGATIGTGIFFVLSEQVPVAGPAVLI  70
            + R+K I  L+  T  G K+LKR L  F LT+ G+GA IGTGIF +       AGP + I
Sbjct  5    VFRKKSIQDLIAATS-GEKSLKRELGAFDLTLLGIGAIIGTGIFVLTGTGAVTAGPGLTI  63

Query  71   SFILAGITAGLTALCYAELSSMIPASGSSYSYAYATLGEGVAFLVAACLILEYGVSAAAV  130
            SF++A +     AL YAE +S +P SGS Y++ YATLGE +AF++   LILEY ++ +AV
Sbjct  64   SFVVAALACLFAALSYAEFASSVPVSGSVYTFTYATLGELMAFIIGWDLILEYMLAVSAV  123

Query  131  AIGWSEYLNNLIHNVFGVHLPNWLLSAPFVADGYKLHLGGTGLINLPAAILVFLCCMLLM  190
            ++GWS Y  + +  + G+HLP  L +AP    G         L NLPA ++V     LL 
Sbjct  124  SVGWSGYFQSFLSGL-GIHLPVALTAAPGAVKGTFT------LFNLPAFVIVMAITYLLY  176

Query  191  RGVTESARINAVMVLIKLCVLILFISIAATAFNAEHLTPFSPHGFAGISAAAGSIFFTFI  250
             G+ ES R+N +MV++K+ V++LFI++AA      +  PF P GF G+ +AA  +FF FI
Sbjct  177  LGIKESKRVNNIMVILKILVVLLFIAVAAVYVKPHNWQPFMPMGFGGVFSAAALVFFAFI  236

Query  251  GLDAVSTAGEEVENPRRNLPLAIISALFVVIIFYILVALTALGAQEQGLFKGQQAGLAVI  310
            G DAVS+A EE +NP ++LP  II +L V  I Y+ V+    G      F G    ++++
Sbjct  237  GFDAVSSAAEETKNPAKDLPKGIIFSLLVCTILYVTVSAIMTGVIPFAQFAGVDHPVSLV  296

Query  311  LQEITGSTWPAIILAAGAVISVFSITLVVLYGQTRILFAMSRDGLAPKIFHRVSTQTLTP  370
            LQ   G  W A I+  GAV+ + ++ LV+LYGQTR++FAMSRDGL P    +V  +  TP
Sbjct  297  LQS-AGQNWVAGIIDIGAVLGMTTVMLVMLYGQTRVMFAMSRDGLVPGSLSKVHPKHKTP  355

Query  371  NANTLIVAVIVSIIAGFVPADVLWDLTSMGTLIAFTVVSIGVLVLRYRMPDAPRGFKVPF  430
               T     + +++   VP D L  L ++GTL AF ++S+ V+VLR + PD PR FK P 
Sbjct  356  YVATWFFGTMSALLGSLVPLDELAKLVNIGTLSAFVLISVAVIVLRKKQPDLPRAFKCPG  415

Query  431  FPALPVLSICACLYLISSLSAIVYVIAAIWAVIAATYYFSCASKNSVL  478
             P +P L+I  CL+LI +L  +  V   +W +I    YF  + K+S L
Sbjct  416  VPVIPGLAILFCLFLILNLGWVTIVRFLVWLLIGLVIYFLYSRKHSKL  463


>Q8W4K3 Cationic amino acid transporter 4, vacuolar [Arabidopsis 
thaliana]
Length=600

 Score = 233 bits (595),  Expect = 4e-73
 Identities = 143/419 (34%), Positives = 231/419 (55%), Gaps = 21/419 (5%)

Query  11   LLRRKPINFLVQETQQGGKTLKRSLTLFQLTMFGVGATIGTGIFFVLSEQVPV-AGPAVL  69
            L+RRK ++ +      G   L + L+   L   GVG TIG G++ ++        GPA+ 
Sbjct  4    LVRRKQVDSVHLIKNDGPHQLAKKLSAVDLVAIGVGTTIGAGVYILVGTVAREHTGPALA  63

Query  70   ISFILAGITAGLTALCYAELSSMIPASGSSYSYAYATLGEGVAFLVAACLILEYGVSAAA  129
            +SF +AG+ A L+A CYAEL+S  P++GS+Y YAY  LGEG+A+LV   L+L+Y +  +A
Sbjct  64   VSFFIAGVAAALSACCYAELASRCPSAGSAYHYAYICLGEGIAWLVGWALVLDYTIGGSA  123

Query  130  VAIGWSEYLNNLIHNVFGVHLPNWLLSAPFVADGYKLHLGGTGLINLP-AAILVFLCCML  188
            +A G +  L +    +   +LP +L          +  + G G++  P AA+L+ +  +L
Sbjct  124  IARGITPNLASFFGGLD--NLPVFLA---------RQTIPGVGIVVDPCAALLIMIVTIL  172

Query  189  LMRGVTESARINAVMVLIKLCVLILFISIAA-----TAFNAEHL-TPFSPHGFAGISAAA  242
            L  G+ ES+ + A++  + +C L+  I +       T +    L + + P G  GI A +
Sbjct  173  LCFGIKESSTVQAIVTSVNVCTLVFIIVVGGYLACKTGWVGYDLPSGYFPFGLNGILAGS  232

Query  243  GSIFFTFIGLDAVSTAGEEVENPRRNLPLAIISALFVVIIFYILVALTALGAQEQGLFKG  302
              +FF++IG D V++  EEV+NP+R+LPL I  AL +  I Y+L+++  +G         
Sbjct  233  AVVFFSYIGFDTVTSTAEEVKNPQRDLPLGIGIALLICCILYMLLSVVIVGLVPYYSLNP  292

Query  303  QQAGLAVILQEITGSTWPAIILAAGAVISVFSITLVVLYGQTRILFAMSRDGLAPKIFHR  362
                 +      +G  W A IL  GA+ ++ +  L  L  Q RI  AM+RDGL P  F  
Sbjct  293  DTPISSAFGD--SGMQWAAYILTTGAITALCASLLGSLLAQPRIFMAMARDGLLPAFFSE  350

Query  363  VSTQTLTPNANTLIVAVIVSIIAGFVPADVLWDLTSMGTLIAFTVVSIGVLVLRYRMPD  421
            +S +T  P  +T+ + V+ + +A F+    L ++ S+GTL+AFT V++ VLVLRY  PD
Sbjct  351  ISPRTQVPVKSTIAIGVLAAALAFFMDVAQLSEMVSVGTLMAFTAVAVCVLVLRYVPPD  409


 Score = 38.9 bits (89),  Expect = 4e-06
 Identities = 20/54 (37%), Positives = 28/54 (52%), Gaps = 0/54 (0%)

Query  425  GFKVPFFPALPVLSICACLYLISSLSAIVYVIAAIWAVIAATYYFSCASKNSVL  478
            GF  PF P LPVL I    YLI ++ A  ++   IW +I +  Y      +S+L
Sbjct  527  GFLCPFVPYLPVLCILINTYLIINIGAGTWIRVLIWLLIGSMIYIFYGRSHSLL  580


>Q9C5D6 Cationic amino acid transporter 9, chloroplastic [Arabidopsis 
thaliana]
Length=569

 Score = 230 bits (587),  Expect = 3e-72
 Identities = 142/392 (36%), Positives = 218/392 (56%), Gaps = 12/392 (3%)

Query  28   GKTLKRSLTLFQLTMFGVGATIGTGIFFVLSEQVPVAGPAVLISFILAGITAGLTALCYA  87
            G +L R L LF L + GVGA+IG G+F V       AGP V ISF+LAG +  L ALCYA
Sbjct  45   GDSLVRRLGLFDLILLGVGASIGAGVFVVTGTVARDAGPGVTISFLLAGASCVLNALCYA  104

Query  88   ELSSMIPAS-GSSYSYAYATLGEGVAFLVAACLILEYGVSAAAVAIGWSEYLNNLIHNVF  146
            ELSS  PA  G +Y Y+Y+   E  AFLV   L+L+Y + AA+++   + Y   L+    
Sbjct  105  ELSSRFPAVVGGAYMYSYSAFNEITAFLVFVQLMLDYHIGAASISRSLASYAVALLELFP  164

Query  147  GVH--LPNWLLSAPFVADGYKLHLGGTGLINLPAAILVFLCCMLLMRGVTESARINAVMV  204
             +   +P W+ S        K  LGG   +N+ A IL+ L  ++L +GV ES+ +N+VM 
Sbjct  165  ALKGSIPLWMGSG-------KELLGGLLSLNILAPILLALLTLVLCQGVRESSAVNSVMT  217

Query  205  LIKLCVLILFISIAATAFNAEHLTPFSPHGFAGISAAAGSIFFTFIGLDAVSTAGEEVEN  264
              K+ ++++ I   A   +  + +PF+P+GF  +   A  +FF+++G DAV+ + EE +N
Sbjct  218  ATKVVIVLVVICAGAFEIDVANWSPFAPNGFKAVLTGATVVFFSYVGFDAVANSAEESKN  277

Query  265  PRRNLPLAIISALFVVIIFYILVALTALGAQEQGLFKGQQAGLAVILQEITGSTWPAIIL  324
            P+R+LP+ I+ +L V I  YI V L   G     L   + A LA       G  + +I++
Sbjct  278  PQRDLPIGIMGSLLVCISLYIGVCLVLTGMVPFSLL-SEDAPLAEAFSS-KGMKFVSILI  335

Query  325  AAGAVISVFSITLVVLYGQTRILFAMSRDGLAPKIFHRVSTQTLTPNANTLIVAVIVSII  384
            + GAV  + +  LV LY Q+R+   + RDGL P IF R+     TP  + +   ++  ++
Sbjct  336  SIGAVAGLTTTLLVGLYVQSRLYLGLGRDGLLPSIFSRIHPTLHTPLHSQIWCGIVAGVL  395

Query  385  AGFVPADVLWDLTSMGTLIAFTVVSIGVLVLR  416
            AG      L  + S+GTL  ++VV+  V+ LR
Sbjct  396  AGIFNVHSLSHILSVGTLTGYSVVAACVVALR  427


 Score = 18.9 bits (37),  Expect = 6.2
 Identities = 7/15 (47%), Positives = 10/15 (67%), Gaps = 0/15 (0%)

Query  329  VISVFSITLVVLYGQ  343
            V+SV +  +  LYGQ
Sbjct  535  VVSVLATAVYALYGQ  549


>Q9ASS7 Cationic amino acid transporter 2, vacuolar [Arabidopsis 
thaliana]
Length=635

 Score = 231 bits (589),  Expect = 6e-72
 Identities = 151/424 (36%), Positives = 231/424 (54%), Gaps = 25/424 (6%)

Query  7    FSQRLLRRKPINFLVQETQQGGKTLKRSLTLFQLTMFGVGATIGTGIFFVLSEQVPV-AG  65
            + + L+RRK ++      Q  G  L R+LT+  L   GVGATIG G++ ++       +G
Sbjct  18   YVRSLVRRKQVDSA--NGQSHGHQLARALTVPHLVAIGVGATIGAGVYILVGTVAREHSG  75

Query  66   PAVLISFILAGITAGLTALCYAELSSMIPASGSSYSYAYATLGEGVAFLVAACLILEYGV  125
            P++ +SF++AGI AGL+A CYAELSS  P++GS+Y Y+Y  +GEGVA+++   LILEY +
Sbjct  76   PSLALSFLIAGIAAGLSAFCYAELSSRCPSAGSAYHYSYICVGEGVAWIIGWALILEYTI  135

Query  126  SAAAVAIGWSEYLNNLIHNVFGVHLPNWLLSAPFVADGYKLHLGGTGLINLP-AAILVFL  184
              +AVA G S  L  +     G  LP  L          +  + G  ++  P AAILVF+
Sbjct  136  GGSAVARGISPNLALIFGGEDG--LPAILA---------RHQIPGLDIVVDPCAAILVFV  184

Query  185  CCMLLMRGVTESARINAVMVLIKLCVLILFISIAATAF-------NAEHLTPFSPHGFAG  237
               LL  G+ ES     ++  + +CVL LF+ +A +           E  T F P G  G
Sbjct  185  VTGLLCMGIKESTFAQGIVTAVNVCVL-LFVIVAGSYLGFKTGWPGYELPTGFFPFGVDG  243

Query  238  ISAAAGSIFFTFIGLDAVSTAGEEVENPRRNLPLAIISALFVVIIFYILVALTALGAQEQ  297
            + A + ++FF FIG D+V++  EEV NP+R+LP+ I  AL +    Y++V++  +G    
Sbjct  244  MFAGSATVFFAFIGFDSVASTAEEVRNPQRDLPIGIGLALLLCCSLYMMVSIVIVGLIPY  303

Query  298  GLFKGQQAGLAVILQEITGSTWPAIILAAGAVISVFSITLVVLYGQTRILFAMSRDGLAP  357
                      +          W   ++  GAV+++ S  +  L  Q RIL AM+RDGL P
Sbjct  304  YAMDPDTPISSAFASH--DMQWAVYLITLGAVMALCSALMGALLPQPRILMAMARDGLLP  361

Query  358  KIFHRVSTQTLTPNANTLIVAVIVSIIAGFVPADVLWDLTSMGTLIAFTVVSIGVLVLRY  417
             IF  ++ +T  P   T+   +  + +A F+    L  + S+GTL+AFT+V+I VL+LRY
Sbjct  362  SIFSDINKRTQVPVKATVATGLCAATLAFFMDVSQLAGMVSVGTLLAFTMVAISVLILRY  421

Query  418  RMPD  421
              PD
Sbjct  422  VPPD  425


 Score = 39.7 bits (91),  Expect = 2e-06
 Identities = 17/54 (31%), Positives = 28/54 (52%), Gaps = 0/54 (0%)

Query  425  GFKVPFFPALPVLSICACLYLISSLSAIVYVIAAIWAVIAATYYFSCASKNSVL  478
            G+  PF P LP++ I   +YL+ +L +  +   ++W +I    Y     KNS L
Sbjct  559  GYMCPFVPLLPIICILINMYLLVNLGSATWARVSVWLLIGVIVYVFYGRKNSSL  612


>Q8GYB4 Cationic amino acid transporter 3, mitochondrial [Arabidopsis 
thaliana]
Length=609

 Score = 216 bits (549),  Expect = 2e-66
 Identities = 141/409 (34%), Positives = 222/409 (54%), Gaps = 27/409 (7%)

Query  23   ETQQGGKTLKRSLTLFQLTMFGVGATIGTGIFFVLSEQVPV-AGPAVLISFILAGITAGL  81
            ET    + L ++LT   L   GVG+TIG G++ ++       +GPA+ +SF++AGI+A L
Sbjct  21   ETHHHHQQLAKALTFPHLIAIGVGSTIGAGVYILVGTVAREHSGPALALSFLIAGISAAL  80

Query  82   TALCYAELSSMIPASGSSYSYAYATLGEGVAFLVAACLILEYGVSAAAVAIGWSEYLNNL  141
            +A CYAELSS  P++GS+Y Y+Y  +GEGVA+L+   LILEY +  + VA G S  L   
Sbjct  81   SAFCYAELSSRFPSAGSAYHYSYICIGEGVAWLIGWALILEYTIGGSTVARGISPNL---  137

Query  142  IHNVFGVH--LPNWLLSAPFVADGYKLHLGGTGLINLP-AAILVFLCCMLLMRGVTESAR  198
               +FG    LP  L          +  + G  ++  P AA+LVF+   L   GV ES  
Sbjct  138  -AMIFGGEDCLPTILA---------RHQIPGLDIVVDPCAAVLVFIVTGLCCLGVKESTF  187

Query  199  INAVMVLIKLCVLILFISIAATAF-------NAEHLTPFSPHGFAGISAAAGSIFFTFIG  251
               ++    + V+I F+ +A +           E  T + P+G  G+   + ++FF +IG
Sbjct  188  AQGIVTTANVFVMI-FVIVAGSYLCFKTGWVGYELPTGYFPYGVDGMLTGSATVFFAYIG  246

Query  252  LDAVSTAGEEVENPRRNLPLAIISALFVVIIFYILVALTALGAQEQGLFKGQQAGLAVIL  311
             D V++  EEV+NPRR+LPL I  +L +  + Y++V++  +G              +   
Sbjct  247  FDTVASMAEEVKNPRRDLPLGIGISLLLCCLLYMMVSVVIVGLVPYYAMDPDTPISSAFS  306

Query  312  QEITGSTWPAIILAAGAVISVFSITLVVLYGQTRILFAMSRDGLAPKIFHRVSTQTLTPN  371
                G  W A ++  GAV+++ S  +  +  Q RIL AM+RDGL P  F  V+ +T  P 
Sbjct  307  SH--GIQWAAYLINLGAVMALCSALMGSILPQPRILMAMARDGLLPSYFSYVNQRTQVPI  364

Query  372  ANTLIVAVIVSIIAGFVPADVLWDLTSMGTLIAFTVVSIGVLVLRYRMP  420
              T+   V  +I+A F+    L  + S+GTL+AFT+V+I +L++RY +P
Sbjct  365  NGTITTGVCAAILAFFMDVSQLAGMVSVGTLVAFTMVAISLLIVRYVVP  413


 Score = 40.4 bits (93),  Expect = 1e-06
 Identities = 18/54 (33%), Positives = 28/54 (52%), Gaps = 0/54 (0%)

Query  425  GFKVPFFPALPVLSICACLYLISSLSAIVYVIAAIWAVIAATYYFSCASKNSVL  478
            GF  PF P LP++ I   +YL+ +L A  +V  ++W  +    Y     +NS L
Sbjct  533  GFICPFVPLLPIVCILINMYLLVNLGAATWVRVSVWLFLGVVVYIFYGRRNSSL  586


 Score = 18.5 bits (36),  Expect = 8.2
 Identities = 17/63 (27%), Positives = 29/63 (46%), Gaps = 8/63 (13%)

Query  20   LVQETQQGGKTLKRSLTLFQLTMFGVGATIGTGIFFVLSEQVP----VAGP-AVLISFIL  74
            L+ E   GG T+ R ++     +FG    + T    +   Q+P    V  P A ++ FI+
Sbjct  118  LILEYTIGGSTVARGISPNLAMIFGGEDCLPT---ILARHQIPGLDIVVDPCAAVLVFIV  174

Query  75   AGI  77
             G+
Sbjct  175  TGL  177


>O43246 Cationic amino acid transporter 4 [Homo sapiens]
Length=635

 Score = 215 bits (547),  Expect = 7e-66
 Identities = 144/425 (34%), Positives = 234/425 (55%), Gaps = 30/425 (7%)

Query  9    QRLLRRKPINFLVQETQQGGKTLKRSLTLFQLTMFGVGATIGTGIFFVLSEQVP--VAGP  66
            Q+L R KP+     ET     +L+R L+   LT+ GVG  +G+G++ VL+  V   VAGP
Sbjct  16   QKLNRLKPLEDSTMET-----SLRRCLSTLDLTLLGVGGMVGSGLY-VLTGAVAKEVAGP  69

Query  67   AVLISFILAGITAGLTALCYAELSSMIPASGSSYSYAYATLGEGVAFLVAACLILEYGVS  126
            AVL+SF +A + + L ALCYAE  + +P +GS+Y + Y ++GE  AFL+   ++LEY + 
Sbjct  70   AVLLSFGVAAVASLLAALCYAEFGARVPRTGSAYLFTYVSMGELWAFLIGWNVLLEYIIG  129

Query  127  AAAVAIGWSEYLNNL----IHNVFGVHLPNWLLSAPFVADGYKLHLGGTGLINLPAAILV  182
             AAVA  WS YL+++    I N    H+ +W    P +  G+       G+I L +A   
Sbjct  130  GAAVARAWSGYLDSMFSHSIRNFTETHVGSW--QVPLL--GHYPDFLAAGIILLASA---  182

Query  183  FLCCMLLMRGVTESARIN----AVMVLIKLCVLILFISIAATAFNAEHLTPFSPHGFAGI  238
            F+ C     G   S+ +N    A+ +L+ L ++IL   +A     +     F+P GF+G+
Sbjct  183  FVSC-----GARVSSWLNHTFSAISLLVILFIVILGFILAQPHNWSADEGGFAPFGFSGV  237

Query  239  SAAAGSIFFTFIGLDAVSTAGEEVENPRRNLPLAIISALFVVIIFYILVALTALGAQEQG  298
             A   S F+ F+G D ++ + EE +NPRR++PLAI  +L +    YILV+ T L      
Sbjct  238  MAGTASCFYAFVGFDVIAASSEEAQNPRRSVPLAIAISLAIAAGAYILVS-TVLTLMVPW  296

Query  299  LFKGQQAGLAVILQEITGSTWPAIILAAGAVISVFSITLVVLYGQTRILFAMSRDGLAPK  358
                  + LA    +  G  W   I+AAG++ ++ ++ L +L+   RI++AM+ DGL  +
Sbjct  297  HSLDPDSALADAFYQ-RGYRWAGFIVAAGSICAMNTVLLSLLFSLPRIVYAMAADGLFFQ  355

Query  359  IFHRVSTQTLTPNANTLIVAVIVSIIAGFVPADVLWDLTSMGTLIAFTVVSIGVLVLRYR  418
            +F  V  +T  P A TL   ++ + +A  +  + L    S+GTL+A+T V+  ++VLR++
Sbjct  356  VFAHVHPRTQVPVAGTLAFGLLTAFLALLLDLESLVQFLSLGTLLAYTFVATSIIVLRFQ  415

Query  419  MPDAP  423
                P
Sbjct  416  KSSPP  420


 Score = 35.8 bits (81),  Expect = 3e-05
 Identities = 16/51 (31%), Positives = 28/51 (55%), Gaps = 0/51 (0%)

Query  426  FKVPFFPALPVLSICACLYLISSLSAIVYVIAAIWAVIAATYYFSCASKNS  476
            F++P  P +P LSI   + L+  LS + +V  +IW ++    YF    ++S
Sbjct  540  FQIPMVPLIPALSIVLNICLMLKLSYLTWVRFSIWLLMGLAVYFGYGIRHS  590


>Q8BLQ7 Cationic amino acid transporter 4 [Mus musculus]
Length=635

 Score = 208 bits (530),  Expect = 2e-63
 Identities = 145/428 (34%), Positives = 237/428 (55%), Gaps = 32/428 (7%)

Query  7    FSQRLLRRKPINFLVQETQQGGKTLKRSLTLFQLTMFGVGATIGTGIFFVLSEQVP--VA  64
            F Q+L R KP+     ET     +L+R L+   LT+ GVG  +G+G++ VL+  V   +A
Sbjct  14   FCQKLNRLKPLEESSMET-----SLRRCLSTLDLTLLGVGGMVGSGLY-VLTGTVAKDMA  67

Query  65   GPAVLISFILAGITAGLTALCYAELSSMIPASGSSYSYAYATLGEGVAFLVAACLILEYG  124
            GPAVL+SF++A + + L ALCYAE  + +P +GS+Y + Y ++GE  AFL+   ++LEY 
Sbjct  68   GPAVLLSFLVAAVASLLAALCYAEFGARVPRTGSAYLFTYVSMGEIWAFLIGWNVLLEYL  127

Query  125  VSAAAVAIGWSEYL----NNLIHNVFGVHLPNWLLSAPFVADGYKLHLGGTGLINLPAAI  180
            +  AAVA  WS YL    N+ I N    HL  W    PF+A  Y   L   G++ + +A 
Sbjct  128  IGGAAVARAWSGYLDAIFNHSIRNFTESHLGVW--QVPFLAH-YPDFL-AAGILLVASA-  182

Query  181  LVFLCCMLLMRGVTESARIN----AVMVLIKLCVLIL-FISIAATAFNAEHLTPFSPHGF  235
              F+ C     G   S+ +N    A+ +++ L +++L FI      ++AE    F+P GF
Sbjct  183  --FVSC-----GARVSSWLNHTFSAISLIVILFIIVLGFILARPHNWSAEE-GGFAPFGF  234

Query  236  AGISAAAGSIFFTFIGLDAVSTAGEEVENPRRNLPLAIISALFVVIIFYILVALTALGAQ  295
            +GI A   + F+ F+G D ++ + EE +NPR  +P+AI  +L +    YILV+ T L   
Sbjct  235  SGILAGTATCFYAFVGFDVIAASSEEAKNPRWAVPMAIAISLSLAAGAYILVS-TVLTLM  293

Query  296  EQGLFKGQQAGLAVILQEITGSTWPAIILAAGAVISVFSITLVVLYGQTRILFAMSRDGL  355
                     + LA       G +W   I+A G++ ++ ++ L  L+   RI++AM+ DGL
Sbjct  294  VPWHSLDPDSALADAFYR-RGYSWAGFIVAVGSICAMNTVLLSNLFSLPRIVYAMAADGL  352

Query  356  APKIFHRVSTQTLTPNANTLIVAVIVSIIAGFVPADVLWDLTSMGTLIAFTVVSIGVLVL  415
              ++F RV  +T  P    L+  V+++++A  +  + L    S+GTL+A+T V+  ++VL
Sbjct  353  FFQVFARVHPRTQVPVVGILVFGVLMALLALLLDLEALVQFLSIGTLLAYTFVATSIIVL  412

Query  416  RYRMPDAP  423
            R++    P
Sbjct  413  RFQKASPP  420


 Score = 29.6 bits (65),  Expect = 0.003
 Identities = 13/44 (30%), Positives = 21/44 (48%), Gaps = 0/44 (0%)

Query  426  FKVPFFPALPVLSICACLYLISSLSAIVYVIAAIWAVIAATYYF  469
            F++P  P  P LSI     L+  LS + ++    W ++    YF
Sbjct  540  FQIPLVPLTPALSILLNTCLMLKLSYLTWLRFIFWLLVGLVVYF  583


>Q84MA5 Cationic amino acid transporter 1 [Arabidopsis thaliana]
Length=594

 Score = 206 bits (525),  Expect = 4e-63
 Identities = 132/420 (31%), Positives = 227/420 (54%), Gaps = 19/420 (5%)

Query  2    KNPVTFSQRLLRRKPINFLVQETQ-QGGKTLKRSLTLFQLTMFGVGATIGTGIFFVLS-E  59
            + P  F  R++ R   +  + E + + G  +K++LT + L  FG+GA IG+GIF +   E
Sbjct  40   ETPSRFMDRIMTRSLDSDEINEMKARSGHEMKKTLTWWDLMWFGIGAVIGSGIFVLTGLE  99

Query  60   QVPVAGPAVLISFILAGITAGLTALCYAELSSMIPASGSSYSYAYATLGEGVAFLVAACL  119
                +GPAV++S++++G++A L+  CY E +  IP +G S++Y    LG+ +AF+ A  +
Sbjct  100  ARNHSGPAVVLSYVVSGVSAMLSVFCYTEFAVEIPVAGGSFAYLRVELGDFMAFIAAGNI  159

Query  120  ILEYGVSAAAVAIGWSEYLNNLIHNVFGVHLP-NWLLSAPFVADGYKLHLGGTGLINLPA  178
            ILEY V  AAVA  W+ Y   L++     H P ++ +    + + Y  HL        P 
Sbjct  160  ILEYVVGGAAVARSWTSYFATLLN-----HKPEDFRIIVHKLGEDYS-HLD-------PI  206

Query  179  AILVF-LCCMLLMRGVTESARINAVMVLIKLCVLILFISIAATAFNAEHLTPFSPHGFAG  237
            A+ V  + C+L + G   S+R N +  +I + V++  I    T  + ++ + F+P+G  G
Sbjct  207  AVGVCAIICVLAVVGTKGSSRFNYIASIIHMVVILFVIIAGFTKADVKNYSDFTPYGVRG  266

Query  238  ISAAAGSIFFTFIGLDAVSTAGEEVENPRRNLPLAIISALFVVIIFYILVALTALGAQEQ  297
            +  +A  +FF +IG DAVST  EE +NP R++P+ ++ ++ V  + Y L+A+T    Q  
Sbjct  267  VFKSAAVLFFAYIGFDAVSTMAEETKNPGRDIPIGLVGSMVVTTVCYCLMAVTLCLMQPY  326

Query  298  GLFKGQQAGLAVILQEITGSTWPAIILAAGAVISVFSITLVVLYGQTRILFAMSRDGLAP  357
                   A  +V    + G  W   I+A GA+  + ++ LV   GQ R +  ++R  + P
Sbjct  327  QQI-DPDAPFSVAFSAV-GWDWAKYIVAFGALKGMTTVLLVGAIGQARYMTHIARAHMMP  384

Query  358  KIFHRVSTQTLTPNANTLIVAVIVSIIAGFVPADVLWDLTSMGTLIAFTVVSIGVLVLRY  417
                +V+ +T TP   T+++    ++IA F    +L DL S+ TL  F  V++ +LV RY
Sbjct  385  PWLAQVNAKTGTPINATVVMLAATALIAFFTKLKILADLLSVSTLFIFMFVAVALLVRRY  444


 Score = 24.3 bits (51),  Expect = 0.13
 Identities = 19/83 (23%), Positives = 33/83 (40%), Gaps = 11/83 (13%)

Query  376  IVAVIVSIIAGFVPADV--LWDLTSMGTLIAFTVVSI---------GVLVLRYRMPDAPR  424
            +V ++  IIAGF  ADV    D T  G    F   ++          V  +     +  R
Sbjct  237  MVVILFVIIAGFTKADVKNYSDFTPYGVRGVFKSAAVLFFAYIGFDAVSTMAEETKNPGR  296

Query  425  GFKVPFFPALPVLSICACLYLIS  447
               +    ++ V ++C CL  ++
Sbjct  297  DIPIGLVGSMVVTTVCYCLMAVT  319


>Q6DCE8 Cationic amino acid transporter 2 [Xenopus laevis]
Length=622

 Score = 201 bits (510),  Expect = 1e-60
 Identities = 134/425 (32%), Positives = 213/425 (50%), Gaps = 48/425 (11%)

Query  27   GGKTLKRSLTLFQLTMFGVGATIGTGIFFVLSEQVPV-AGPAVLISFILAGITAGLTALC  85
            G   L R L+   L   GVG+T+G G++ +  E   V +GP+++ISF++A + + L  LC
Sbjct  26   GSSDLCRCLSTLDLVALGVGSTLGAGVYVLAGEVAKVDSGPSIIISFLIAALASVLAGLC  85

Query  86   YAELSSMIPASGSSYSYAYATLGEGVAFLVAACLILEYGVSAAAVAIGWSEYLNNLIHNV  145
            YAE  + +P +GS+Y Y+Y T+GE  AF+    LIL Y +  ++VA  WS   + L+   
Sbjct  86   YAEFGARVPLTGSAYLYSYVTVGELWAFITGWNLILSYVIGTSSVARAWSATFDELV---  142

Query  146  FGVHLPNWLLSAPFVADGYKLHLGGTGLINLP---AAILVFLCCMLLMRGVTESARINAV  202
             G  + N+L        G  +H+   GL   P   A  L+ L   LL  GV ES  +N V
Sbjct  143  -GKKIGNFL--------GNTMHMDLPGLAEYPDIFAVCLIILLAGLLSFGVKESTAVNKV  193

Query  203  MVLIKLCVLILFISIAATAFNAEH-----------------------------LTPFSPH  233
               I + VL+  I+      N ++                                F P 
Sbjct  194  FTAINILVLLFVIASGCVTGNLKYWKMSKEDLWATKQSVSNHSIGNETGLDFGAGGFMPF  253

Query  234  GFAGISAAAGSIFFTFIGLDAVSTAGEEVENPRRNLPLAIISALFVVIIFYILVALTALG  293
            GF+G  A A + F+ F+G D ++T GEEV+NP++++PL I+ +L +    Y  V+ +   
Sbjct  254  GFSGTLAGAATCFYAFVGFDCIATTGEEVKNPQKSIPLGIVLSLSICFFAYFGVSASLTL  313

Query  294  AQEQGLFKGQQAGLAVILQEITGSTWPAIILAAGAVISVFSITLVVLYGQTRILFAMSRD  353
                 L   Q    A    E  G      I+A G++ ++ +  L  ++   RILFAM+RD
Sbjct  314  MMPYHLLDSQSPLPAAF--EYVGWNVAKYIVAVGSLCALTTSLLGSMFPMPRILFAMARD  371

Query  354  GLAPKIFHRVSTQTLTPNANTLIVAVIVSIIAGFVPADVLWDLTSMGTLIAFTVVSIGVL  413
            GL  +   RVS++  +P   T++  V+ +++A       L D+ S+GTL+A+T+VS  VL
Sbjct  372  GLLFQPLSRVSSRQ-SPVIATIVSGVVAALMAFLFNLKALVDMMSIGTLLAYTLVSTCVL  430

Query  414  VLRYR  418
            +LRY+
Sbjct  431  LLRYQ  435


 Score = 46.2 bits (108),  Expect = 2e-08
 Identities = 43/162 (27%), Positives = 78/162 (48%), Gaps = 15/162 (9%)

Query  331  SVFSITLVVLYGQTRILFAMSRDG-LAPKIFHRVSTQTLTPNANT--LIVAVIVSIIAGF  387
            ++ S  +++L  Q +  F  S DG L  +    +S    TP+ ++  L+   +++I    
Sbjct  423  TLVSTCVLLLRYQPQTDFGKSPDGNLQEQNISSISHLPETPSVHSSALVTRCVIAITLLV  482

Query  388  VPADVLWDLTSMGTL------IAFTVVSI-GV---LVLRYRMPD--APRGFKVPFFPALP  435
              A V+  + S   L      ++  V+S+ G+   LV+ +R P   +   F VPF P LP
Sbjct  483  CVASVVSTVGSQCLLSGRAWCLSLLVLSLLGIIIALVIIWRQPQNQSKATFMVPFVPVLP  542

Query  436  VLSICACLYLISSLSAIVYVIAAIWAVIAATYYFSCASKNSV  477
            V+SI   +YL+  LS   ++  A+W  +    YF    ++S+
Sbjct  543  VVSILVNIYLMVQLSTDTWLRYAVWMAVGFVIYFGYGIRHSI  584


>O64759 Cationic amino acid transporter 5 [Arabidopsis thaliana]
Length=569

 Score = 199 bits (507),  Expect = 1e-60
 Identities = 133/451 (29%), Positives = 228/451 (51%), Gaps = 24/451 (5%)

Query  7    FSQRLLRRKPI-NFLVQETQQGGKTLKRSLTLFQLTMFGVGATIGTGIFFVLSEQV-PVA  64
            F  RL+ R    N   +  +Q    +KR LT + L  FG G+ IG GIF +  ++    A
Sbjct  39   FKNRLVSRSDDENERFELKKQSEHEMKRCLTWWDLVWFGFGSVIGAGIFVLTGQEAHEQA  98

Query  65   GPAVLISFILAGITAGLTALCYAELSSMIPASGSSYSYAYATLGEGVAFLVAACLILEYG  124
            GPA+++S++++G++A L+  CY E +  IP +G S++Y    LG+  AF+ A  ++LE  
Sbjct  99   GPAIVLSYVVSGLSAMLSVFCYTEFAVEIPVAGGSFAYLRIELGDFAAFITAGNILLESI  158

Query  125  VSAAAVAIGWSEYLNNLIHNVFGVHLPNWLLSAPFVADGYKLHLGGTGLINLPAAILVFL  184
            V  AAVA  W+ Y   L++       PN L     ++ G+        L++  A +++  
Sbjct  159  VGTAAVARAWTSYFATLLN-----RSPNALRIKTDLSSGF-------NLLDPIAVVVIAA  206

Query  185  CCMLLMRGVTESARINAVMVLIKLCVLILFISIAATAFNAEHLTPFSPHGFAGISAAAGS  244
               +      +++ +N +   I   V+   I       +  +LTPF P G  G+  AA  
Sbjct  207  SATIASISTRKTSLLNWIASAINTLVIFFVIIAGFIHADTSNLTPFLPFGPEGVFRAAAV  266

Query  245  IFFTFIGLDAVSTAGEEVENPRRNLPLAIISALFVVIIFYILVALTALGAQEQGLFKGQQ  304
            ++F + G D+++T  EE +NP R++P+ ++ ++ ++ + Y L+AL +L   ++       
Sbjct  267  VYFAYGGFDSIATMAEETKNPSRDIPIGLLGSMSIITVIYCLMAL-SLSMMQKYTDIDPN  325

Query  305  AGLAVILQEITGSTWPAIILAAGAVISVFSITLVVLYGQTRILFAMSRDGLAPKIFHRVS  364
            A  +V  Q + G  W   ++A GA+  + ++ LV   GQ R +  ++R  + P IF  V 
Sbjct  326  AAYSVAFQSV-GMKWGKYLVALGALKGMTTVLLVGALGQARYVTHIARTHMIPPIFALVH  384

Query  365  TQTLTPNANTLIVAVIVSIIAGFVPADVLWDLTSMGTLIAFTVVSIGVLVLRYRM-PDAP  423
             +T TP    L+VA+  ++IA F   DVL  L S+ TL  FT++ I +LV RY +  D P
Sbjct  385  PKTGTPINANLLVAIPSALIAFFSGLDVLASLLSISTLFIFTMMPIALLVRRYYVRQDTP  444

Query  424  RGFKVPFFPALPVLSICACLYLISSLSAIVY  454
            R   +        L  C    ++SS+    Y
Sbjct  445  RVHLIK-------LITCLLFVVVSSMGTSAY  468


 Score = 18.5 bits (36),  Expect = 8.1
 Identities = 20/62 (32%), Positives = 29/62 (47%), Gaps = 15/62 (24%)

Query  394  WDLTSMGTLIAFTVVSIGVLVLRYRMPDAPRGFKVPFFPALPVLSICACLYLISSLSAIV  453
            WDL   G     +V+  G+ VL  +      G      PA+ VLS     Y++S LSA++
Sbjct  71   WDLVWFGF---GSVIGAGIFVLTGQEAHEQAG------PAI-VLS-----YVVSGLSAML  115

Query  454  YV  455
             V
Sbjct  116  SV  117


>P18581 Cationic amino acid transporter 2 [Mus musculus]
Length=657

 Score = 197 bits (501),  Expect = 3e-59
 Identities = 142/447 (32%), Positives = 231/447 (52%), Gaps = 53/447 (12%)

Query  5    VTFSQRLLRRKPINFLVQETQQGGKTLKRSLTLFQLTMFGVGATIGTGIFFVLSEQVPV-  63
            +TF++ L+RRK +     E  +    L R LT   L   GVG+T+G G++ +  E     
Sbjct  8    LTFARCLIRRKIVTLDSLEDSK----LCRCLTTVDLIALGVGSTLGAGVYVLAGEVAKAD  63

Query  64   AGPAVLISFILAGITAGLTALCYAELSSMIPASGSSYSYAYATLGEGVAFLVAACLILEY  123
            +GP++++SF++A + + +  LCYAE  + +P +GS+Y Y Y T+GE  AF+    LIL Y
Sbjct  64   SGPSIVVSFLIAALASVMAGLCYAEFGARVPKTGSAYLYTYVTVGELWAFITGWNLILSY  123

Query  124  GVSAAAVAIGWSEYLNNLIHNVFGVHLPNWLLSAPFVADGYKLHLGGTGLINLP---AAI  180
             +  ++VA  WS   + L++   G           F    +K++   TGL   P   A  
Sbjct  124  VIGTSSVARAWSGTFDELLNKQIG----------QFFKTYFKMNY--TGLAEYPDFFAVC  171

Query  181  LVFLCCMLLMRGVTESARINAVMVLIKLCVLILF----------------------ISIA  218
            LV L   LL  GV ESA +N     I + VL+                        IS +
Sbjct  172  LVLLLAGLLSFGVKESAWVNKFFTAINILVLLFVMVAGFVKGNVANWKISEEFLKNISAS  231

Query  219  ATAFNAEHLTP------FSPHGFAGISAAAGSIFFTFIGLDAVSTAGEEVENPRRNLPLA  272
            A    +E+ T       F P+GF G  A A + F+ F+G D ++T GEEV NP++ +P+ 
Sbjct  232  AREPPSENGTSIYGAGGFMPYGFTGTLAGAATCFYAFVGFDCIATTGEEVRNPQKAIPIG  291

Query  273  IISALFVVIIFYILVALTALGAQEQGLFKGQQAGLAVILQEITGSTWPA-IILAAGAVIS  331
            I+++L V  + Y  V+  AL          +++ L V  + +  S  PA  +++AG++ +
Sbjct  292  IVTSLLVCFMAYFGVS-AALTLMMPYYLLDEKSPLPVAFEYVRWS--PAKYVVSAGSLCA  348

Query  332  VFSITLVVLYGQTRILFAMSRDGLAPKIFHRVSTQTLTPNANTLIVAVIVSIIAGFVPAD  391
            + +  L  ++   RILFAM+RDGL  +   RVS +  +P A T+   VI +++A      
Sbjct  349  LSTSLLGSMFPLPRILFAMARDGLLFRFLARVSKRQ-SPVAATMTAGVISAVMAFLFDLK  407

Query  392  VLWDLTSMGTLIAFTVVSIGVLVLRYR  418
             L D+ S+GTL+A+++V+  VL+LRY+
Sbjct  408  ALVDMMSIGTLMAYSLVAACVLILRYQ  434


 Score = 48.9 bits (115),  Expect = 3e-09
 Identities = 26/82 (32%), Positives = 43/82 (52%), Gaps = 2/82 (2%)

Query  398  SMGTLIAFTVVSIGVLVLRYRMPDAPR--GFKVPFFPALPVLSICACLYLISSLSAIVYV  455
            S+  L  F V+ + V++  +R P   +   F VPF P LP  SI   +YL+  LSA  ++
Sbjct  525  SLALLALFLVLCVAVILTIWRQPQNQQKVAFMVPFLPFLPAFSILVNIYLMVQLSADTWI  584

Query  456  IAAIWAVIAATYYFSCASKNSV  477
              +IW  +    YF+   ++S+
Sbjct  585  RFSIWMALGFLIYFAYGIRHSL  606


 Score = 20.4 bits (41),  Expect = 2.1
 Identities = 12/26 (46%), Positives = 14/26 (54%), Gaps = 1/26 (4%)

Query  111  VAFLVAACLILE-YGVSAAAVAIGWS  135
            +AFL+    IL  YGV A A    WS
Sbjct  500  LAFLILGLSILTTYGVQAIARLEAWS  525


 Score = 19.6 bits (39),  Expect = 3.6
 Identities = 11/42 (26%), Positives = 20/42 (48%), Gaps = 0/42 (0%)

Query  179  AILVFLCCMLLMRGVTESARINAVMVLIKLCVLILFISIAAT  220
            A L+    +L   GV   AR+ A  + +    L+L +++  T
Sbjct  501  AFLILGLSILTTYGVQAIARLEAWSLALLALFLVLCVAVILT  542



Lambda      K        H        a         alpha
   0.328    0.140    0.415    0.792     4.96 

Gapped
Lambda      K        H        a         alpha    sigma
   0.267   0.0410    0.140     1.90     42.6     43.6 

Effective search space used: 2847161


  Database: 813426bc9558b8ef5aa36fa3c355033c.SwissProt.fasta
    Posted date:  May 9, 2024  7:38 AM
  Number of letters in database: 7,051
  Number of sequences in database:  12



Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Neighboring words threshold: 11
Window for multiple hits: 40