BLASTP 2.12.0+
Reference: Stephen F. Altschul, Thomas L. Madden, Alejandro A.
Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J.
Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of
protein database search programs", Nucleic Acids Res. 25:3389-3402.
Reference for composition-based statistics: Alejandro A. Schaffer,
L. Aravind, Thomas L. Madden, Sergei Shavirin, John L. Spouge, Yuri
I. Wolf, Eugene V. Koonin, and Stephen F. Altschul (2001),
"Improving the accuracy of PSI-BLAST protein database searches with
composition-based statistics and other refinements", Nucleic Acids
Res. 29:2994-3005.
Database: 6f495b21362f9785467239be772260cd.SwissProt.fasta
18 sequences; 18,360 total letters
Query= ACIAD1353
Length=980
Score E
Sequences producing significant alignments: (Bits) Value
Q6PF24 Presequence protease, mitochondrial [Xenopus laevis] 434 7e-139
Q6C0U8 Presequence protease, mitochondrial [Yarrowia lipolytica (... 430 8e-138
Q28BR5 Presequence protease, mitochondrial [Xenopus tropicalis] 426 1e-135
Q7ZVZ6 Presequence protease, mitochondrial [Danio rerio] 404 2e-127
Q5JRX3 Presequence protease, mitochondrial [Homo sapiens] 401 2e-126
Q5RDG3 Presequence protease, mitochondrial [Pongo abelii] 394 1e-123
Q8VY06 Presequence protease 2, chloroplastic/mitochondrial [Arabi... 393 4e-123
Q6FUI7 Presequence protease, mitochondrial [Candida glabrata (str... 390 1e-122
Q9LJL3 Presequence protease 1, chloroplastic/mitochondrial [Arabi... 390 4e-122
Q6CWW6 Presequence protease, mitochondrial [Kluyveromyces lactis ... 382 8e-120
Q8K411 Presequence protease, mitochondrial [Mus musculus] 379 2e-118
Q46205 Protein HypA [Clostridium perfringens (strain 13 / Type A)] 377 3e-118
P32898 Presequence protease, mitochondrial [Saccharomyces cerevis... 340 3e-104
A0A0L7KF24 Falcilysin [Plasmodium falciparum (isolate HB3)] 240 3e-68
Q76NL8 Falcilysin [Plasmodium falciparum (isolate 3D7)] 240 3e-68
O22941 Insulin-degrading enzyme-like 1, peroxisomal [Arabidopsis ... 42.0 3e-06
P11913 Mitochondrial-processing peptidase subunit beta [Neurospor... 41.6 3e-06
Q40983 Stromal processing peptidase, chloroplastic [Pisum sativum] 37.4 8e-05
>Q6PF24 Presequence protease, mitochondrial [Xenopus laevis]
Length=1027
Score = 434 bits (1116), Expect = 7e-139
Identities = 306/983 (31%), Positives = 484/983 (49%), Gaps = 66/983 (7%)
Query 25 VEALDILVSEYAHKVTGAVHYHLATSHDENVFLVAFRTQPMDSKGTAHILEHTALCGSEK 84
V L + + +H TGA + H+A N+F V FRT P+DS G HILEHT LCGS+K
Sbjct 51 VPELFLTAVKLSHDNTGAKYLHVAREDSNNLFSVQFRTTPLDSTGVPHILEHTVLCGSQK 110
Query 85 FPVRDPFFLMIRRSLNTFMNAFTSADWTAYPFATQNKKDFQNLLSVYLDAAFAANLNPLD 144
+P RDPFF M+ RSL+TFMNAFT++D+T YPF+TQN KDFQNLLSVYLDA F L LD
Sbjct 111 YPCRDPFFKMLNRSLSTFMNAFTASDYTMYPFSTQNAKDFQNLLSVYLDAVFFPCLRELD 170
Query 145 FAQEGIRIELENGEP-----VYKGVVFNEMKGAMSAPSDQLYHQLAYHLFPETTYHYNSG 199
F QEG R+E EN E ++KG+VFNEMKGA + L L P+ TY SG
Sbjct 171 FWQEGWRLEHENPEDPNSPLIFKGIVFNEMKGAFTDNEKVFSQHLQNKLLPDHTYSVVSG 230
Query 200 GDPKDIPDLSYEQLVDFYKSHYHPSNAVFMTFGNQNAYDLQEQFEKLALSKFEKGTTLYS 259
G+P +IPDL++EQL +F+ +HYHPSNA F T+GN +Q + ALSKF + S
Sbjct 231 GEPLNIPDLTWEQLKEFHATHYHPSNARFFTYGNLPLEMHLKQIHEDALSKFGRIDPKTS 290
Query 260 -KPEKRLATPIQVTETYAVDS--EDLDDKTYHVLAWLLPQASDIKLRLGLRLVEGILLEN 316
P++R +P + + + VDS D + +T + +LL + +D L L+ ++++
Sbjct 291 VPPQERWQSPREYSISCGVDSFASDPEKQTMVSVNFLLSEITDSFEAFTLSLLSSLMVDG 350
Query 317 SASPLRHYLETCGYAQSTGPLMGVDDSNFEMTFYCGVQGSNAAHADEFREGVLNILQQVA 376
SP L P G ++ E F G+QG N +++ + + + ++A
Sbjct 351 PNSPFYKALIEANLGTDFSPDTGFNNYTRETYFSIGLQGINKEDSEKVKHIINRTINEIA 410
Query 377 SQPVDQALVDAILHQIELHQREINGDGMPYGLSLILNGLSSAIHHNDPVHVWDVDTAIEQ 436
Q ++ ++A+LH++E+ + +GL+L S H DPV + + I +
Sbjct 411 EQGIEPERIEALLHKLEIQMKH---QSTSFGLTLASYIASCWNHEGDPVDLLKIGDKISR 467
Query 437 VKEELKD-PMWLSNLIQTHLLDNPHRVQMTLVPDAEKSMKDQAEEKARLAEIGAHLTEED 495
++ LK+ P +L + ++ + N HR+ +++ PD + K++ E+ +L + L+EE+
Sbjct 468 FRQCLKENPKFLQDKVKQYFQVNQHRMMLSMSPDEQHYDKEEQLEEEKLTQKVKALSEEE 527
Query 496 RAQINANTEALNQRQDTPDDLDLLPKVGLEDVPADLHIVQGQLREIISNRHDYPLNLYHA 555
R QI L Q P D LP + + D+ + + + I+ D P+
Sbjct 528 RKQIYEKGLELISLQSKPQDFSCLPALKVSDIEPQIPLTDLE----IAYAGDVPVQYCTQ 583
Query 556 GTNG-IYYQQV--LIEIPDEVVHSPYFNLLSILMGEVGAGEYDYLTLQQLQTAVSGGLGM 612
TNG +Y++ V L +P+E+ PY L ++ ++G G Y+Y Q +GG+ +
Sbjct 584 PTNGMVYFRAVSSLNTLPEEL--KPYVPLFCSVITKLGCGVYNYREQAQQMELTTGGMSV 641
Query 613 GASLRSKVDDKNKISAWLTLTTKSLNEKR-DAIQLLKLAFEKLRFDEKDRIIELLQQRKT 671
+ S + + ++ L+ D + L F FD+++R+ L++
Sbjct 642 CPHIISDDSSLDTYEQGILFSSLCLDRNMPDMMHLWSEIFNSPHFDDEERLRVLVRMSAQ 701
Query 672 RWISRLSGSGHSYAMQIASRNMSALAQRDYHNTGLGALNWLSNLVDQIEQDESAYDALIH 731
+ + SGH YA ASR ++ + +G+ + + + + + +++
Sbjct 702 EMSNGIPDSGHVYASIRASRTLTPTGELQELFSGMDQVKMIKRIAEMPDM-----GSILR 756
Query 732 ELKAIHLKLL----------QAPKQFLLVCE--EQFADALV---EDIQTVWDHLEIES-- 774
+L I +L AP+Q + E F + ++ + + H+ +S
Sbjct 757 KLSRIRKYVLLSDNMRCSINAAPQQMETASKEMEHFLTGITRSKKERKAIRPHVVEKSSN 816
Query 775 ---DVIEIQHLAQQNHNQDEAWL-IQTNVQFCAS--------AYPAVEVTHPDAAPLMVL 822
EI A + D + Q FC S V THPD A L +L
Sbjct 817 PSPSGSEISRTATRKLVGDPTFKPCQMKTHFCLSFPVNYIGECVRTVPYTHPDYASLRIL 876
Query 823 AAYLRNGYLHSAIREKGGAYGGGA--SYDGNACSFRFYSYRDPRLAETFQDFEASIDWLL 880
A + +LH IREKGGAYGGGA S+DG F FYSYRDP T F+ + DW
Sbjct 877 ARIMTAKFLHGEIREKGGAYGGGAKLSFDG---IFGFYSYRDPNSLSTLSTFQKATDWAK 933
Query 881 HTSQQPHQLEEAILGLVSSMDKPGSPAGEAITACYALLHARTPAFRKTLRTRLLNVTLDD 940
++EA L + S++D P +P+ + + LH + ++ R L VT D
Sbjct 934 SGQFSQQDVDEAKLSVFSAVDSPIAPSDKGMN---HFLHGISDEMKQRHREELFAVTHSD 990
Query 941 LKRVAQHYLQEQQVTR--AVVAP 961
L + YL Q TR A++ P
Sbjct 991 LTNASNKYLTAGQCTRGTAILGP 1013
>Q6C0U8 Presequence protease, mitochondrial [Yarrowia lipolytica
(strain CLIB 122 / E 150)]
Length=990
Score = 430 bits (1106), Expect = 8e-138
Identities = 316/982 (32%), Positives = 489/982 (50%), Gaps = 81/982 (8%)
Query 6 TETINQTVHPAFQLVRQHHVEALDILVSEYAHKVTGAVHYHLATSHDENVFLVAFRTQPM 65
T ++ +H F ++R + D+ + H TGA H H+A NVF + F+T P
Sbjct 25 TLSVGDNIH-GFNVLRTKEIPEFDLQATLLEHS-TGAQHLHIARDDSNNVFSIGFKTNPP 82
Query 66 DSKGTAHILEHTALCGSEKFPVRDPFFLMIRRSLNTFMNAFTSADWTAYPFATQNKKDFQ 125
D G HILEHT LCGSEK+ VRDPFF M+ RSL FMNA T+ D+T YPFAT N D +
Sbjct 83 DRTGVPHILEHTTLCGSEKYQVRDPFFKMLNRSLANFMNAMTAQDYTFYPFATTNATDMK 142
Query 126 NLLSVYLDAAFAANLNPLDFAQEGIRIELENGEP-----VYKGVVFNEMKGAMSAPSDQL 180
NL VYLDA L LDF+QEG R+E E+ + + KGVVFNEMKG MS +
Sbjct 143 NLRDVYLDATLKPLLRELDFSQEGWRLENEDSKDKTSPIILKGVVFNEMKGQMSNAAYAF 202
Query 181 YHQLAYHLFPETTYHYNSGGDPKDIPDLSYEQLVDFYKSHYHPSNAVFMTFGNQNAYD-- 238
Y + ++P NSGGDP IP+L+YE L F+ HY+PSNA ++G+ + D
Sbjct 203 YIRYLEKIYPSLN---NSGGDPLVIPELTYEGLKKFHADHYNPSNAKTFSYGDISVADHL 259
Query 239 --LQEQFEKLALSKFEKGTTLYSKPEKRLATPIQVTETYAVDSEDLDDKTYH--VLAWLL 294
L +FE +SK T A ++ E +D+ LD H ++WL+
Sbjct 260 EALNAKFENCEISKTPGNTERLPLEFSSAAENTRIVEEGPIDTL-LDTSKQHKMSMSWLM 318
Query 295 PQASDIKLRLGLRLVEGILLENSASPLRHYLETCGYAQSTGPLMGVDDSNFEMTFYCGVQ 354
DI ++++ +L++ +SPL L G S P G+D + F G+Q
Sbjct 319 GSPKDIYESFCVKIISSLLIDGHSSPLHQKLIDSGLGSSYSPNTGLDSAPGANIFSVGLQ 378
Query 355 GSNAAHADEFREGVLNILQQVASQPVDQALVDAILHQIELHQREINGDGMPYGLSLILNG 414
G + + +L+ ++ ++ D+ +D +LHQ EL +++ N +G++L+
Sbjct 379 GVTESDLTKVETVILDTIKTTVAEGFDKGRIDGLLHQTELARKDQNA---KFGMALMNGV 435
Query 415 LSSAIHHNDPVHVWDVDTAIEQVKEELK-DPMWLSNLIQTHLLDNPH-RVQMTLVPDAEK 472
L + DP+ + ++ +++ ++++ DP +L +++ +LLDN + QM PD EK
Sbjct 436 LPGWFNQVDPLEALEWNSVLDRFNKDMEADPEFLQKVMKKYLLDNKYFHFQMNPNPDYEK 495
Query 473 SMKDQAEEKARLAEIGAHLTEEDRAQINANTEALNQRQDTPDDLDLLPKVGLEDVPADLH 532
+++++ +E L + A LTE D+ +I L + Q+ P++LD LP + + D+P
Sbjct 496 NVQEKEDE--ILTDKLAKLTESDKEEIFETGANLEKMQEEPENLDCLPTLHVSDIPRSKP 553
Query 533 IVQGQLREIISNRHDYPLNLYHAGTNGI-YYQQV--LIEIPDEVVHSPYFNLLSILMGEV 589
V + ++ YP+ A TNG+ Y+ + L +P E + P+ L + + +
Sbjct 554 RV-----ALEHTKNPYPIQWRLAPTNGLTYFHSISSLEGLPHE--YYPFLPLFTSSLTFL 606
Query 590 GAGEYDYLTLQQLQTAV---SGGLGMGASLRSKVDDKNKISAWLTLTTKSLNEKRDAIQL 646
G + T+ QL+ + +GGL S S L+L + LN D + L
Sbjct 607 GTKD---KTMGQLEDEIKLNTGGLDFSVSCSSSP---------LSLPSSQLNFAMDGVAL 654
Query 647 LK-------LAFEKLR---FDEKDRIIELLQQRKTRWISRLSGSGHSYAMQIASRNMSAL 696
K L E LR F +++ ++ + L+ SGHS+AM A+ ++S +
Sbjct 655 DKNVETMFGLFQELLRNTDFTNVEKLKTMIAASTANLSNALAQSGHSFAMLRAASDISPV 714
Query 697 AQRDYHNTGLGALNWLSNLVDQIEQDESAYDALIHELKAIHLKLLQAPKQFLLVCEEQFA 756
+ D G+ + +LS L + EQ L+ E+ + LQ +F L E++FA
Sbjct 715 KKIDDILGGVAQVRFLSELAAKSEQQ------LVDEV----IPKLQEIAKFALTREQRFA 764
Query 757 DALVEDIQTVWDHL--------EIESDVIEIQHLA-QQNHNQDEAWLIQTNVQFCASAYP 807
+D+QT D L E I L+ + + V + A P
Sbjct 765 VTCGQDMQTKNDELVRKFAESFETNESPFNISSLSIPMTTPTSTLFKLPFQVNYAGIAIP 824
Query 808 AVEVTHPDAAPLMVLAAYLRNGYLHSAIREKGGAYGGGASYDGNACSFRFYSYRDPRLAE 867
V TH D APL VLA L + +LH IREKGGAYGGGASY+ F +YSYRDP L
Sbjct 825 GVPYTHADGAPLQVLANMLTHKHLHREIREKGGAYGGGASYNPTDGFFSYYSYRDPNLER 884
Query 868 TFQDFEASIDWLLHTSQQPHQLEEAILGLVSSMDKPGSPAGEAITACYALLHARTPAFRK 927
T Q + + +W + L+EA L L +D P S E + A YA + T R+
Sbjct 885 TLQTCQEAGEWSVKKDWSSSDLQEAKLSLFQRIDAPISVKSEGM-ALYA--NGLTYEQRE 941
Query 928 TLRTRLLNVTLDDLKRVAQHYL 949
R +LL+V +DD+KRVA+ YL
Sbjct 942 KRRRQLLDVAVDDVKRVAKQYL 963
>Q28BR5 Presequence protease, mitochondrial [Xenopus tropicalis]
Length=1027
Score = 426 bits (1094), Expect = 1e-135
Identities = 306/985 (31%), Positives = 477/985 (48%), Gaps = 70/985 (7%)
Query 25 VEALDILVSEYAHKVTGAVHYHLATSHDENVFLVAFRTQPMDSKGTAHILEHTALCGSEK 84
V L + + +H TGA + H+A N+F V FRT P+DS G HILEHT LCGS+K
Sbjct 51 VPELFLTAVKLSHDNTGAKYLHVAREDSNNLFSVQFRTTPLDSTGVPHILEHTVLCGSQK 110
Query 85 FPVRDPFFLMIRRSLNTFMNAFTSADWTAYPFATQNKKDFQNLLSVYLDAAFAANLNPLD 144
+P RDPFF M+ RSL+TFMNAFT++D+T YPF+TQN KDFQNLLSVYLDA F L LD
Sbjct 111 YPCRDPFFKMLNRSLSTFMNAFTASDYTMYPFSTQNAKDFQNLLSVYLDAVFFPCLRELD 170
Query 145 FAQEGIRIELENGEP-----VYKGVVFNEMKGAMSAPSDQLYHQLAYHLFPETTYHYNSG 199
F QEG R+E EN E ++KG+VFNEMKGA + L L P+ TY SG
Sbjct 171 FWQEGWRLEHENPEDPNSPLIFKGIVFNEMKGAFTDNEKVFSQHLQNKLLPDHTYSVVSG 230
Query 200 GDPKDIPDLSYEQLVDFYKSHYHPSNAVFMTFGNQNAYDLQEQFEKLALSKFEKGTTLYS 259
G+P +IPDL++EQL F+ +HYHPSNA F T+GN +Q + ALSKFE+ S
Sbjct 231 GEPLNIPDLTWEQLKQFHATHYHPSNARFFTYGNLPLEIHLKQIHEDALSKFERIDPKTS 290
Query 260 -KPEKRLATPIQVTETYAVDS--EDLDDKTYHVLAWLLPQASDIKLRLGLRLVEGILLEN 316
P++R +P + + + DS D + +T + +LL + +D L L+ ++++
Sbjct 291 VPPQERWQSPREYSISCGTDSFASDPEKQTTVSVNFLLSEITDTFEAFTLSLLSSLMVDG 350
Query 317 SASPLRHYLETCGYAQSTGPLMGVDDSNFEMTFYCGVQGSNAAHADEFREGVLNILQQVA 376
SP L P G ++ E F G+QG N +++ + + + +VA
Sbjct 351 PNSPFYKALIEANLGTDFSPDTGFNNYTRETYFSIGLQGINKEDSEKVKAIINKTINEVA 410
Query 377 SQPVDQALVDAILHQIELHQREINGDGMPYGLSLILNGLSSAIHHNDPVHVWDVDTAIEQ 436
++ ++A+LH++E+ + +GL+L S H DPV + + I +
Sbjct 411 EHGIEAERIEALLHKLEIQMKH---QSTSFGLTLASYVASCWNHEGDPVDLLKIGDKISR 467
Query 437 VKEELKD-PMWLSNLIQTHLLDNPHRVQMTLVPDAEKSMKDQAEEKARLAEIGAHLTEED 495
+E LK+ P +L + ++ + + HR+ +++ PD + K+ E +L + L+EE+
Sbjct 468 FRECLKENPKFLQDKVKQYFQVSQHRMTLSMSPDEQHYDKEAQLEAEKLTQKVKALSEEE 527
Query 496 RAQINANTEALNQRQDTPDDLDLLPKVGLEDVPADLHIVQGQLREIISNRHDYPLNLYHA 555
R QI L + Q P D LP + + D+ + + I+ D P+
Sbjct 528 RKQIYEKGLELIRLQSKPQDASCLPALKVSDIEPKIPLTDLD----ITYAGDVPVQYCAQ 583
Query 556 GTNG-IYYQQV--LIEIPDEVVHSPYFNLLSILMGEVGAGEYDYLTLQQLQTAVSGGLGM 612
TNG +Y++ V L +P+E+ PY L ++ ++G G Y+Y Q +GG+ +
Sbjct 584 PTNGMVYFRAVSSLNTLPEEL--KPYVPLFCSVITKLGCGVYNYREQAQQMELTTGGMSV 641
Query 613 GASLRSKVDDKNKISAWLTLTTKSLNEKR---DAIQLLKLAFEKLRFDEKDRIIELLQQR 669
+ + DD N + + SL R D + L F FD+++R+ L++
Sbjct 642 CPHIIT--DDSNLDTYEQGVVFSSLCLDRNLPDMMHLWSEIFNSPHFDDEERLRVLVRMS 699
Query 670 KTRWISRLSGSGHSYAMQIASRNMSALAQRDYHNTGLGALNWLSNLVDQIEQDESAYDAL 729
+ + SGH YA A R ++ + +G+ + + + + E +
Sbjct 700 AQEMSNGIPDSGHVYASIRAGRTLTPAGELQELFSGMDQVKMIKRIAEMPEM-----GPI 754
Query 730 IHELKAIHLKLL---------QAPKQFLLVCEEQFADALVEDIQTVWDHLEIESDVI--- 777
+ +L I +L A Q + V ++ L ++ + I V+
Sbjct 755 LRKLSRIRKYVLLSDNMRCSVNATPQQMPVASKEIEHFLAGISRSKKERKSIRPHVVEKS 814
Query 778 --------EIQHLAQQNHNQDEA---------WLIQTNVQFCASAYPAVEVTHPDAAPLM 820
EI A + D + + V + V THPD A L
Sbjct 815 SSPSSSGSEISRRATRKLVGDPTFKPCQMKTHFSLSFPVNYIGECVRTVPYTHPDYASLR 874
Query 821 VLAAYLRNGYLHSAIREKGGAYGGGA--SYDGNACSFRFYSYRDPRLAETFQDFEASIDW 878
+LA + +LH IREKGGAYGGGA S+DG F FYSYRDP T F+ + DW
Sbjct 875 ILARIMTAKFLHGEIREKGGAYGGGAKLSFDG---IFGFYSYRDPNSLSTLSTFQKAADW 931
Query 879 LLHTSQQPHQLEEAILGLVSSMDKPGSPAGEAITACYALLHARTPAFRKTLRTRLLNVTL 938
++EA L + S++D P +P+ + + LH + ++ R +L VT
Sbjct 932 AKSGQFTQQDVDEAKLSVFSAVDSPIAPSDKGMN---HFLHGISDEMKQKHREQLFAVTH 988
Query 939 DDLKRVAQHYLQEQQVTR--AVVAP 961
DL + YL Q TR A++ P
Sbjct 989 SDLTNASNKYLTAGQCTRGTAILGP 1013
>Q7ZVZ6 Presequence protease, mitochondrial [Danio rerio]
Length=1023
Score = 404 bits (1037), Expect = 2e-127
Identities = 302/993 (30%), Positives = 471/993 (47%), Gaps = 66/993 (7%)
Query 8 TINQTVHPAFQLVRQHHVEALDILVSEYAHKVTGAVHYHLATSHDENVFLVAFRTQPMDS 67
T+ Q +H F + V L + + +H TGA + H A N+F V FRT PMDS
Sbjct 36 TVGQKIHN-FTVKEVTAVPDLFLTAVKLSHDATGAQYLHAARDDSNNLFSVLFRTTPMDS 94
Query 68 KGTAHILEHTALCGSEKFPVRDPFFLMIRRSLNTFMNAFTSADWTAYPFATQNKKDFQNL 127
G HILEHT LCGS++FP RDPFF M+ RSL+TFMNAFT++D+T YPF+TQN KDFQNL
Sbjct 95 TGVPHILEHTVLCGSQRFPCRDPFFKMLNRSLSTFMNAFTASDYTMYPFSTQNAKDFQNL 154
Query 128 LSVYLDAAFAANLNPLDFAQEGIRIELEN-----GEPVYKGVVFNEMKGAMSAPSDQLYH 182
LSVYLDA F L LDF QEG R+E EN V+KGVVFNEMKG S +++LY
Sbjct 155 LSVYLDAVFFPCLRELDFWQEGWRLEHENPTDPSSPLVFKGVVFNEMKGVFS-DNERLYA 213
Query 183 Q-LAYHLFPETTYHYNSGGDPKDIPDLSYEQLVDFYKSHYHPSNAVFMTFGNQNAYDLQE 241
Q L L P+ TY SGG+P IP+L++EQL F+ +HYHPSNA F T+G+ +
Sbjct 214 QHLQNKLLPDHTYSVVSGGEPLAIPELTWEQLKHFHATHYHPSNARFFTYGDLPLEQHLQ 273
Query 242 QFEKLALSKFEKGTTLYSKPEKRLATPIQVTETYAVD------SEDLDDKTYHVLAWLLP 295
Q E+ A+SKFE+ + P + TP V + D + +++LL
Sbjct 274 QIEEEAMSKFERTEPNTAVPPQ---TPWDKPRMDHVSCRPDALAPDPVKQNTLCMSFLLG 330
Query 296 QASDIKLRLGLRLVEGILLENSASPLRHYLETCGYAQSTGPLMGVDDSNFEMTFYCGVQG 355
+D L L+ +++ SP L G D S + +F G+QG
Sbjct 331 DITDTFEMFTLSLLSSLMMSGPNSPFYKALIEPKIGSDFSSSAGFDGSTRQASFTIGLQG 390
Query 356 SNAAHADEFREGVLNILQQVASQPVDQALVDAILHQIELHQREINGDGMPYGLSLILNGL 415
+ + + + + + ++ ++A+LH+IE+ + +GL+L
Sbjct 391 MAEDDTETVKHIIAQTIDDIIASGFEEEQIEALLHKIEIQMKH---QSTSFGLALASYIA 447
Query 416 SSAIHHNDPVHVWDVDTAIEQVKEELKD-PMWLSNLIQTHLLDNPHRVQMTLVPDAEKSM 474
S H DPV + + ++ + ++ LK+ P +L +Q + +N H++ +++ PD E+ +
Sbjct 448 SLWNHDGDPVQLLKISESVSRFRQCLKENPRYLQEKVQHYFKNNTHQLTLSMSPD-ERFL 506
Query 475 KDQAE-EKARLAEIGAHLTEEDRAQINANTEALNQRQDTPDDLDLLPKVGLEDVPADLHI 533
+ QAE E+ +L + L+ EDR I L Q T D LP + + D+ +
Sbjct 507 EKQAEAEEQKLQQKIQILSSEDRKDIYEKGLQLLAVQSTTQDASCLPALKVSDIEPIIPY 566
Query 534 VQGQLREIISNRHDYPLNLYHAGTNGIYYQQVLIEI---PDEVVHSPYFNLLSILMGEVG 590
Q P+ TNG+ Y + + I P+++ Y L ++ ++G
Sbjct 567 TPVQ----PGAAGGVPVQYCEQPTNGMVYFRAMSNINSLPEDL--KIYVPLFCSVITKMG 620
Query 591 AGEYDYLTLQQLQTAVSGGLGMGASLRSKVDDKNKISAWLTLTTKSLNEK-RDAIQLLKL 649
+G DY Q +GGL + + +D + + L++ L D QL
Sbjct 621 SGMLDYRQQAQRIELKTGGLSVSPQIIPDTEDLDLYEQGIILSSSCLERNLPDMFQLWSD 680
Query 650 AFEKLRFDEKDRIIELLQQRKTRWISRLSGSGHSYAMQIASRNMSALAQRDYHNTGLGAL 709
F RFD+++R+ L+ + +S SGH YAM A+R+++ A +G+ +
Sbjct 681 LFNSPRFDDEERLRVLVMMSAQELSNGISYSGHMYAMTRAARSLTPTADLQESFSGMDQV 740
Query 710 NWLSNLVDQIEQDESAYDALIHELKAI--HLKLLQAPKQFLLVCEEQFADALVEDIQTVW 767
++ + + + +++ +L I HL + + L ++ D E + +
Sbjct 741 KFMKRIAEMTD-----LTSILRKLPRIKRHLFNPENMRCALNATPQKMPDVAAEVERFIG 795
Query 768 -------DHLEIESDVIE-----------IQHLAQQNH----NQDEAWLIQTNVQFCASA 805
+ + V+E + L + H + + NV F +
Sbjct 796 NIAGNRKERKPVRPSVVERALGPEAGAAATRKLISEAHFKPCQMKTYFQLPFNVNFVSEC 855
Query 806 YPAVEVTHPDAAPLMVLAAYLRNGYLHSAIREKGGAYGGGASYDGNACSFRFYSYRDPRL 865
V TH D A L +L + +LH IREKGGAYGGGA G F FYSYRDP
Sbjct 856 VRTVPFTHADYASLCILGRMMTAKFLHGEIREKGGAYGGGARMGGGGL-FSFYSYRDPNS 914
Query 866 AETFQDFEASIDWLLHTSQQPHQLEEAILGLVSSMDKPGSPAGEAITACYALLHARTPAF 925
+T F ++W ++EA L + S++D P +P+ + + L+ T
Sbjct 915 TQTLSAFRGGVEWARAGKFTQQDIDEAKLSVFSAVDAPVAPSDKGLG---RFLNGITDEM 971
Query 926 RKTLRTRLLNVTLDDLKRVAQHYLQEQQVTRAV 958
++ R RL VT +L VA YL Q T V
Sbjct 972 KQAHRERLFAVTERNLIDVAGRYLGIGQQTCGV 1004
>Q5JRX3 Presequence protease, mitochondrial [Homo sapiens]
Length=1037
Score = 401 bits (1030), Expect = 2e-126
Identities = 303/991 (31%), Positives = 461/991 (47%), Gaps = 78/991 (8%)
Query 25 VEALDILVSEYAHKVTGAVHYHLATSHDENVFLVAFRTQPMDSKGTAHILEHTALCGSEK 84
V L + + H TGA + HLA N+F V FRT PMDS G HILEHT LCGS+K
Sbjct 57 VPELFLTAVKLTHDDTGARYLHLAREDTNNLFSVQFRTTPMDSTGVPHILEHTVLCGSQK 116
Query 85 FPVRDPFFLMIRRSLNTFMNAFTSADWTAYPFATQNKKDFQNLLSVYLDAAFAANLNPLD 144
+P RDPFF M+ RSL+TFMNAFT++D+T YPF+TQN KDFQNLLSVYLDA F L LD
Sbjct 117 YPCRDPFFKMLNRSLSTFMNAFTASDYTLYPFSTQNPKDFQNLLSVYLDATFFPCLRELD 176
Query 145 FAQEGIRIELEN-GEP----VYKGVVFNEMKGAMSAPSDQLYHQLAYHLFPETTYHYNSG 199
F QEG R+E EN +P V+KGVVFNEMKGA + L L P+ TY SG
Sbjct 177 FWQEGWRLEHENPSDPQTPLVFKGVVFNEMKGAFTDNERIFSQHLQNRLLPDHTYSVVSG 236
Query 200 GDPKDIPDLSYEQLVDFYKSHYHPSNAVFMTFGNQNAYDLQEQFEKLALSKFEK------ 253
GDP IP+L++EQL F+ +HYHPSNA F T+GN +Q + ALSKF+K
Sbjct 237 GDPLCIPELTWEQLKQFHATHYHPSNARFFTYGNFPLEQHLKQIHEEALSKFQKIEPSTV 296
Query 254 --GTTLYSKPEKRLATPIQVTETYAVDSEDLDDKTYHVLAWLLPQASDIKLRLGLRLVEG 311
T + KP + Q+T + D +T +++LLP +D L L+
Sbjct 297 VPAQTPWDKPRE-----FQITCGPDSFATDPSKQTTISVSFLLPDITDTFEAFTLSLLSS 351
Query 312 ILLENSASPLRHYLETCGYAQSTGPLMGVDDSNFEMTFYCGVQGSNAAHADEFREGVLNI 371
+L SP L G P +G + E F G+QG + R +
Sbjct 352 LLTSGPNSPFYKALIESGLGTDFSPDVGYNGYTREAYFSVGLQGIAEKDIETVRSLIDRT 411
Query 372 LQQVASQPVDQALVDAILHQIELHQREINGDGMPYGLSLILNGLSSAIHHNDPVHVWDVD 431
+ +V + + ++A+LH+IE+ + +GL L S H DPV + +
Sbjct 412 IDEVVEKGFEDDRIEALLHKIEIQMKH---QSTSFGLMLTSYIASCWNHDGDPVELLKLG 468
Query 432 TAIEQVKEELKD-PMWLSNLIQTHLLDNPHRVQMTLVPDAEKSMKDQAEEKARLAEIGAH 490
+ + ++ L++ P +L ++ + +N H++ +++ PD + K E +L +
Sbjct 469 NQLAKFRQCLQENPKFLQEKVKQYFKNNQHKLTLSMRPDDKYHEKQAQVEATKLKQKVEA 528
Query 491 LTEEDRAQINANTEALNQRQDTPDDLDLLPKVGLEDVPADLHIVQGQLREIISNRHDYPL 550
L+ DR QI L +Q P D LP + + D+ + + + +++ D P+
Sbjct 529 LSPGDRQQIYEKGLELRSQQSKPQDASCLPALKVSDIEPTIPVTE---LDVVLTAGDIPV 585
Query 551 NLYHAGTNGIYYQQV---LIEIPDEVVHSPYFNLLSILMGEVGAGEYDYLTLQQLQTAVS 607
TNG+ Y + L +P+E+ PY L ++ ++G G DY Q +
Sbjct 586 QYCAQPTNGMVYFRAFSSLNTLPEEL--RPYVPLFCSVLTKLGCGLLDYREQAQQIELKT 643
Query 608 GGLGMGASLRSKVDDKNKISAWLTLTTKSLNEKR---DAIQLLKLAFEKLRFDEKDRIIE 664
G GM AS DD + + + SL R D +QL F F+E++
Sbjct 644 G--GMSASPHVLPDDSHMDTYEQGVLFSSLCLDRNLPDMMQLWSEIFNNPCFEEEEHFKV 701
Query 665 LLQQRKTRWISRLSGSGHSYAMQIASRNMSALAQRDYHNTGLGALNWLSNLVDQIEQDES 724
L++ + + SGH YA A R ++ +G+ + + + + +
Sbjct 702 LVKMTAQELANGIPDSGHLYASIRAGRTLTPAGDLQETFSGMDQVRLMKRIAEMTD---- 757
Query 725 AYDALIHELKAIHLKLL---------QAPKQFLLVCEEQFADALVEDIQTVWDHLEIESD 775
++ +L I LL A Q + E+ D L ++ + +
Sbjct 758 -IKPILRKLPRIKKHLLNGDNMRCSVNATPQQMPQTEKAVEDFLRSIGRSKKERRPVRPH 816
Query 776 VIE------------IQHLAQQNHN-----QDEAWLIQTN------VQFCASAYPAVEVT 812
+E + H +Q + W ++T+ V + V T
Sbjct 817 TVEKPVPSSSGGDAHVPHGSQVIRKLVMEPTFKPWQMKTHFLMPFPVNYVGECIRTVPYT 876
Query 813 HPDAAPLMVLAAYLRNGYLHSAIREKGGAYGGGASYDGNACSFRFYSYRDPRLAETFQDF 872
PD A L +LA + +LH+ IREKGGAYGGGA N F YSYRDP ET Q F
Sbjct 877 DPDHASLKILARLMTAKFLHTEIREKGGAYGGGAKLSHNGI-FTLYSYRDPNTIETLQSF 935
Query 873 EASIDWLLHTSQQPHQLEEAILGLVSSMDKPGSPAGEAITACYALLHARTPAFRKTLRTR 932
++DW ++EA L + S++D P +P+ + + L+ + ++ R +
Sbjct 936 GKAVDWAKSGKFTQQDIDEAKLSVFSTVDAPVAPSDKGMD---HFLYGLSDEMKQAHREQ 992
Query 933 LLNVTLDDLKRVAQHYLQEQQVTR--AVVAP 961
L V+ D L V+ YL + T A++ P
Sbjct 993 LFAVSHDKLLAVSDRYLGTGKSTHGLAILGP 1023
>Q5RDG3 Presequence protease, mitochondrial [Pongo abelii]
Length=1037
Score = 394 bits (1011), Expect = 1e-123
Identities = 298/986 (30%), Positives = 454/986 (46%), Gaps = 76/986 (8%)
Query 25 VEALDILVSEYAHKVTGAVHYHLATSHDENVFLVAFRTQPMDSKGTAHILEHTALCGSEK 84
V L + + H TGA + HLA N+F V FRT PMDS G HILEHT LCGS+K
Sbjct 57 VPELFLTAVKLIHDDTGARYLHLAREDTNNLFSVQFRTTPMDSTGVPHILEHTVLCGSQK 116
Query 85 FPVRDPFFLMIRRSLNTFMNAFTSADWTAYPFATQNKKDFQNLLSVYLDAAFAANLNPLD 144
+P RDPFF M+ RSL+TFMNAFT++D+T YPF+TQN KDFQNLLSVYLDA F L LD
Sbjct 117 YPCRDPFFRMLNRSLSTFMNAFTASDYTLYPFSTQNPKDFQNLLSVYLDATFFPCLRELD 176
Query 145 FAQEGIRIELENGEP-----VYKGVVFNEMKGAMSAPSDQLYHQLAYHLFPETTYHYNSG 199
F QEG R+E EN V+KGVVFNEMKGA + L L P+ TY SG
Sbjct 177 FWQEGWRLEHENPRDPQTALVFKGVVFNEMKGAFTDNERIFSQHLQNRLLPDHTYSVVSG 236
Query 200 GDPKDIPDLSYEQLVDFYKSHYHPSNAVFMTFGNQNAYDLQEQFEKLALSKFEK------ 253
GDP I +L++EQL F+ +HYHPSNA F T+GN +Q + ALSKF+K
Sbjct 237 GDPLCILELTWEQLKQFHATHYHPSNARFFTYGNFPLEQHLKQIHEEALSKFQKIEPSTA 296
Query 254 --GTTLYSKPEKRLATPIQVTETYAVDSEDLDDKTYHVLAWLLPQASDIKLRLGLRLVEG 311
T + KP + Q+T + D +T +++LLP +D L L+
Sbjct 297 VPAQTPWDKPRE-----FQITCGPDSFATDPSKQTTVSVSFLLPDITDTFEAFTLSLLSS 351
Query 312 ILLENSASPLRHYLETCGYAQSTGPLMGVDDSNFEMTFYCGVQGSNAAHADEFREGVLNI 371
+L SP L G P +G + E F G+QG + R V
Sbjct 352 LLTSGPNSPFYKALIESGLGTDFSPDVGYNGYTREAYFSVGLQGIAEKDIETVRSLVDRT 411
Query 372 LQQVASQPVDQALVDAILHQIELHQREINGDGMPYGLSLILNGLSSAIHHNDPVHVWDVD 431
+ +V + + ++A+LH+IE+ + +GL L S H DPV + +
Sbjct 412 IDEVVEKGFEDDRIEALLHKIEIQMKH---QSTSFGLMLTSYIASCWNHDGDPVELLKLG 468
Query 432 TAIEQVKEELKD-PMWLSNLIQTHLLDNPHRVQMTLVPDAEKSMKDQAEEKARLAEIGAH 490
+ + ++ L++ P +L ++ + +N H++ +++ PD + K E +L +
Sbjct 469 NQLAKFRQCLQENPKFLQEKVKQYFKNNQHKLTLSMRPDDKYHEKQAQVEATKLKQKVEA 528
Query 491 LTEEDRAQINANTEALNQRQDTPDDLDLLPKVGLEDVPADLHIVQGQLREIISNRHDYPL 550
L+ DR QI L +Q P D LP + + D+ + + + +++ D P+
Sbjct 529 LSPGDRQQIYEKGLELRTQQSKPQDASCLPALKVSDIEPTIPVTE---LDVVLTAGDIPV 585
Query 551 NLYHAGTNGIYYQQV---LIEIPDEVVHSPYFNLLSILMGEVGAGEYDYLTLQQLQTAVS 607
TNG+ Y + L +P+E+ PY L ++ ++G G DY Q +
Sbjct 586 QYCAQPTNGMVYFRAFSSLNTLPEEL--RPYVPLFCSVLTKLGCGLLDYREQAQQIELKT 643
Query 608 GGLGMGASLRSKVDDKNKISAWLTLTTKSLNEKR---DAIQLLKLAFEKLRFDEKDRIIE 664
G GM AS DD + + + SL R D + L F F+E++
Sbjct 644 G--GMSASPHVLPDDSHMDTYEQGVLFSSLCLDRNLPDMMHLWSEIFNNPCFEEEEHFKV 701
Query 665 LLQQRKTRWISRLSGSGHSYAMQIASRNMSALAQRDYHNTGLGALNWLSNLVDQIEQDES 724
L++ + + SGH YA A R ++ +G+ + + + + +
Sbjct 702 LVKMTAQELTNAIPDSGHLYASIRAGRTLTPAGDLQETFSGMDRVRLMKRIAEMTD---- 757
Query 725 AYDALIHELKAIHLKLL---------QAPKQFLLVCEEQFADALVEDIQTVWDHLEIESD 775
++ +L I LL A Q + E+ D L ++ + +
Sbjct 758 -IKPILRKLPRIKKHLLNGDNMRCSVNATPQQMSQTEKAVEDFLRSIGRSKKERRPVRPH 816
Query 776 VIE------------IQHLAQ-----QNHNQDEAWLIQTN------VQFCASAYPAVEVT 812
+E + H +Q + W ++T+ V + V
Sbjct 817 TVEKPVPSSSGGDAHVPHGSQIIRKLVTEPTFKPWQMKTHFLMPFPVNYVGECIRTVPYM 876
Query 813 HPDAAPLMVLAAYLRNGYLHSAIREKGGAYGGGASYDGNACSFRFYSYRDPRLAETFQDF 872
PD A L +LA + +LH+ IREKGGAYGGGA N F YSYRDP ET Q F
Sbjct 877 DPDHASLKILARLMTAKFLHTEIREKGGAYGGGAKLSHNGI-FSLYSYRDPNTIETLQSF 935
Query 873 EASIDWLLHTSQQPHQLEEAILGLVSSMDKPGSPAGEAITACYALLHARTPAFRKTLRTR 932
++DW ++EA L + S++D P +P+ + + L+ + ++ R +
Sbjct 936 GKAVDWAKSGKFTQQDIDEAKLSVFSTVDAPIAPSNKGMD---YFLYGLSDGMKQAHREQ 992
Query 933 LLNVTLDDLKRVAQHYLQEQQVTRAV 958
L V+ D L V+ YL + T ++
Sbjct 993 LFAVSHDKLLAVSNRYLGTGKSTHSL 1018
>Q8VY06 Presequence protease 2, chloroplastic/mitochondrial [Arabidopsis
thaliana]
Length=1080
Score = 393 bits (1010), Expect = 4e-123
Identities = 283/951 (30%), Positives = 465/951 (49%), Gaps = 35/951 (4%)
Query 17 FQLVRQHHVEALDILVSEYAHKVTGAVHYHLATSHDENVFLVAFRTQPMDSKGTAHILEH 76
F+ V + + + HK TG ++ + VF + FRT P DS G HILEH
Sbjct 106 FEKVSEEFISECKSKAVLFKHKKTGCEVMSVSNDDENKVFGIVFRTPPKDSTGIPHILEH 165
Query 77 TALCGSEKFPVRDPFFLMIRRSLNTFMNAFTSADWTAYPFATQNKKDFQNLLSVYLDAAF 136
+ LCGS K+P+++PF +++ SL+TF+NAFT D T YP A+ NKKDF NL+ VYLDA F
Sbjct 166 SVLCGSRKYPMKEPFVELLKGSLHTFLNAFTYPDRTCYPVASTNKKDFYNLVDVYLDAVF 225
Query 137 AANL--NPLDFAQEGIRIELEN-GEPV-YKGVVFNEMKGAMSAPSDQLYHQLAYHLFPET 192
+ F QEG EL + E + YKGVVFNEMKG S P + L L PE
Sbjct 226 FPKCVDDVHTFQQEGWHYELNDPSEDISYKGVVFNEMKGVYSQPDNILGRVTQQALCPEN 285
Query 193 TYHYNSGGDPKDIPDLSYEQLVDFYKSHYHPSNAVFMTFGNQNAYD----LQEQFEKLAL 248
TY +SGGDPKDIP L++E+ +F++ +YHPSNA +G+ + L E +
Sbjct 286 TYGVDSGGDPKDIPKLTFEKFKEFHRQYYHPSNARIWFYGDDDPVHRLRVLSEYLDMFDA 345
Query 249 SKFEKGTTLYSKPEKRLATPIQVTETY-AVDSEDLDDKTYHVLAWLL-PQASDIKLRLGL 306
S + + +P+K + P ++ E Y A + DL K L WLL + D++ +L L
Sbjct 346 SPARDSSKV--EPQKLFSRPRRIVEKYPAGEDGDLKKKHMVCLNWLLSDKPLDLQTQLAL 403
Query 307 RLVEGILLENSASPLRHYLETCGYAQSTGPLMGVDDSNFEMTFYCGVQGSNAAHADEFRE 366
++ ++L ASPLR L G ++ G++D + F G++G + + + E
Sbjct 404 GFLDHLMLGTPASPLRKILLESGLGEAL-VNSGMEDELLQPQFSIGLKGVSDDNVQKVEE 462
Query 367 GVLNILQQVASQPVDQALVDAILHQIELHQREINGDGMPYGLSLILNGLSSAIHHNDPVH 426
V+N L+++A + D V+A ++ IE RE N P GLSL+L ++ I+ DP
Sbjct 463 LVMNTLRKLADEGFDTDAVEASMNTIEFSLRENNTGSSPRGLSLMLQSIAKWIYDMDPFE 522
Query 427 VWDVDTAIEQVKEELKD---PMWLSNLIQTHLLDNPHRVQMTLVPDAEKSMKDQAEEKAR 483
+ ++ +K + + S LI+ ++L+NPH V + + PD EK+ ++AEEK+
Sbjct 523 PLKYEEPLKSLKARIAEKGSKSVFSPLIEEYILNNPHCVTIEMQPDPEKASLEEAEEKSI 582
Query 484 LAEIGAHLTEEDRAQINANTEALNQRQDTPDDLDLL---PKVGLEDVPADLHIVQGQLRE 540
L ++ A +TEED ++ TE L +Q+TPD D L P + L D+P + V ++ +
Sbjct 583 LEKVKASMTEEDLTELARATEELRLKQETPDPPDALKCVPSLNLSDIPKEPIYVPTEVGD 642
Query 541 IISNRHDYPLNLYHAGTNGIYYQQVLIEIPDEVVHS--PYFNLLSILMGEVGAGEYDYLT 598
I + + TN I Y +V+ ++ V H L + E+G + ++
Sbjct 643 I----NGVKVLRNDLFTNNILYTEVVFDM-GSVKHELLQLIPLFCQSLLEMGTQDLTFVQ 697
Query 599 LQQLQTAVSGGLGMGASLRSKVDDKNKISAWLTLTTKSL-NEKRDAIQLLKLAFEKLRFD 657
L QL +GG+ + L S V ++ + + + KS+ D L+ +++RF
Sbjct 698 LNQLIGRKTGGISV-YPLTSSVYGRDDPCSKIIVRGKSMVGRAEDLFNLMNCVLQEVRFT 756
Query 658 EKDRIIELLQQRKTRWISRLSGSGHSYAMQIASRNMSALAQRDYHNTGLGALNWLSNLVD 717
++ R + + Q + R +RL GSG A ++ GL L +L L
Sbjct 757 DQQRFKQFVSQSRARMENRLRGSGQGIAAARMDAMLNVAGWMSEQMGGLSYLEFLHTLEQ 816
Query 718 QIEQDESAYDALIHELKAIHLKLLQAPKQFLLVCEEQFADALVEDIQTVWDHLEI--ESD 775
+++QD + + E++ L + +V +L + V L++ E+
Sbjct 817 KVDQDWEGISSSLEEIRRSFLS-----RNGCIVNMTADGKSLTNTEKYVGKFLDLLPENP 871
Query 776 VIEIQHLAQQNHNQDEAWLIQTNVQFCASAYPAVEVTHPDAAPLMVLAAYLRNGYLHSAI 835
E+ + ++EA +I T V + A + V++ ++ N +L +
Sbjct 872 SGELVTWDARLPLRNEAIVIPTQVNYVGKAGNIYSSGYKLDGSSYVISKHISNTWLWDRV 931
Query 836 REKGGAYGGGASYDGNACSFRFYSYRDPRLAETFQDFEASIDWLLHTSQQPHQLEEAILG 895
R GGAYGG +D ++ F F SYRDP L +T ++ + D+L L +AI+G
Sbjct 932 RVSGGAYGGSCDFDSHSGVFSFLSYRDPNLLKTLDIYDGTGDFLRGLDVDEDTLTKAIIG 991
Query 896 LVSSMDKPGSPAGEAITACYALLHARTPAFRKTLRTRLLNVTLDDLKRVAQ 946
+ +D P + T+ L T R+ R +L+ +L D K A+
Sbjct 992 TIGDVDSYQLPDAKGYTSLLRHLLNVTDEERQIRREEILSTSLKDFKEFAE 1042
>Q6FUI7 Presequence protease, mitochondrial [Candida glabrata
(strain ATCC 2001 / BCRC 20586 / JCM 3761 / NBRC 0622 / NRRL
Y-65 / CBS 138)]
Length=990
Score = 390 bits (1001), Expect = 1e-122
Identities = 297/975 (30%), Positives = 459/975 (47%), Gaps = 61/975 (6%)
Query 17 FQLVRQHHVEALDILVSEYAHKVTGAVHYHLATSHDENVFLVAFRTQPMDSKGTAHILEH 76
FQ+ R V L + + H+ TGA H H+ NVF +AFRT P D+ G HILEH
Sbjct 29 FQVRRAVPVPELKLTAVDLIHEQTGAEHLHIDRDDKNNVFSIAFRTLPPDATGVPHILEH 88
Query 77 TALCGSEKFPVRDPFFLMIRRSLNTFMNAFTSADWTAYPFATQNKKDFQNLLSVYLDAAF 136
T LCGSEK+PVRDPFF M+ +SL FMNA T D+T +PFAT N +DF NL VYL++
Sbjct 89 TTLCGSEKYPVRDPFFKMLNKSLANFMNAMTGPDYTFFPFATTNARDFVNLRDVYLNSTL 148
Query 137 AANLNPLDFAQEGIRIELE-----NGEPVYKGVVFNEMKGAMSAPSDQLYHQLAYHLFPE 191
L DF QEG R+E + ++KGVVFNEMKG +S + Q +++P
Sbjct 149 RPLLKEQDFYQEGWRLEHSEVTNPKSDIIFKGVVFNEMKGQVSNADYHFWSQFQQNIYPS 208
Query 192 TTYHYNSGGDPKDIPDLSYEQLVDFYKSHYHPSNAVFMTFGNQNAYDLQEQFEKLALSKF 251
NSGGDP+ I DL Y+ LVDF+ ++YHPSNA T+G ++ L++ L K
Sbjct 209 LN---NSGGDPQKITDLHYQDLVDFHHANYHPSNARTFTYG---SFPLED-----TLKKV 257
Query 252 EKGTTLYSKP--EKRLATPIQVTETYAVDSEDLDD-------KTYHVLAWLLPQASDIKL 302
+ Y K K+L P+++ ET + E D +T L W + +D+
Sbjct 258 NEEFRAYGKRIINKKLPKPLELIETKELTLEGQIDPMLPAEKQTKTSLTWKCGEPTDLYE 317
Query 303 RLGLRLVEGILLENSASPLRHYLETCGYAQSTGPLMGVDDSNFEMTFYCGVQGSNAAHAD 362
L+++ +LL+ S + L G GV+ G+QGS + +
Sbjct 318 TFLLKILGNLLLDGHDSIMYKGLIESGLGHDFSVNTGVESMTAANFLTVGIQGSQ--NVE 375
Query 363 EFREGVLNILQQVASQPVDQALVDAILHQIELHQREINGDGMPYGLSLILNGLSSAIHHN 422
EF+ V ++ ++ VD VDAI+HQ+EL +++ D +GL ++ + L +
Sbjct 376 EFKSKVFDLFKEFIENDVDSNKVDAIIHQLELSKKDQKAD---FGLQILYSILPGWTNGI 432
Query 423 DPVHVWDVDTAIEQVKEELKD--PMWLSNLIQTHLLDNPHRVQMTLVPDAEKSMKDQAEE 480
DP+ + D I ++K + K+ N++ +++D P+ T+ E S K AEE
Sbjct 433 DPIEGLEFDELIGRLKSDFKENGTKIFKNILDKYIIDQPY-FHFTMKGSEEFSSKLAAEE 491
Query 481 KARLAEIGAHLTEEDRAQINANTEALNQRQDTPDDLDLLPKVGLEDVPADLHIVQGQLRE 540
+L + L E DR I L Q+ +DL LP +G+ D+ + +
Sbjct 492 STKLDKKLKELDETDRKAIFERGLLLEAAQNHKEDLSCLPTLGVADISRKV-----DTYD 546
Query 541 IISNRHDYPLNLYHAGTNGIYY----QQVLIEIPDEVVHSPYFNLLSILMGEVGAGEYDY 596
+ +N + + + + TNGI Y + + IP E+ P+ +L + + +G Y
Sbjct 547 LNTNAN---ITVRNTATNGISYIRGKKLINDMIPLELY--PFLSLFAASLTHLGTKTTPY 601
Query 597 LTLQQLQTAVSGGLGMGASLRSKVDDKNKISAWLTLTTKSLNEKRDAI-QLLKLAFEKLR 655
+ +GG+ S+ + + + ++ SLNEK D I LK +
Sbjct 602 GAIDNEIKLHTGGISTNISVNADPTTLQP-NLYFDMSGFSLNEKSDYIFNFLKTILMETD 660
Query 656 FD-EKDRIIELLQQRKTRWISRLSGSGHSYAMQIASRNMSALAQRDYHNTGLGALNWLSN 714
F KD++ L+ + S ++ SGH+ A AS ++S +A H +G+ +S
Sbjct 661 FSTHKDKLKVLINSIASSNTSHIADSGHTVARSFASGHLSTVAAIQEHISGVEHYKLISR 720
Query 715 LVDQIEQDESAYDALIHELKAIHLKLLQAPKQFLLV---CEEQFADALVEDIQTVWDHLE 771
L + D+ +I +L + ++ + C+ Q E V
Sbjct 721 LCSIMNDDKLFQSEVIDKLVMLQRIIVNSQNMEFFASVDCQAQENKIRKEVDYFVSTLPN 780
Query 772 IESDVIEIQHLAQQNHNQDEAWL----IQTNVQFCASAYPAVEVTHPDAAPLMVLAAYLR 827
SD+ A D L V + A AY V TH D A L VLA L
Sbjct 781 TSSDISGAIQTACVPRYSDSQVLNLIKFPFQVHYTAQAYNGVSYTHKDGAALQVLANMLT 840
Query 828 NGYLHSAIREKGGAYGGGASYDGNACSFRFYSYRDPRLAETFQDFEASIDWLLHTSQ-QP 886
+LH IREKGGAYGGGA++ + F +YSYRDP + Q FE S ++L+ ++
Sbjct 841 FKHLHKEIREKGGAYGGGATFSALSGIFSYYSYRDPNPLASIQTFEKSASYVLNDAKWTQ 900
Query 887 HQLEEAILGLVSSMDKPGSPAGEAITACYALLHARTPAFRKTLRTRLLNVTLDDLKRVAQ 946
L+E+ L + +D P SP E T T R+ R +LL+ +L D+ RVA+
Sbjct 901 SDLDESKLSIFQQVDAPISPKSEGSTFFNL---GVTDEMRQVRREQLLDTSLLDIHRVAE 957
Query 947 HYLQEQQVTRAVVAP 961
Y+ + VV P
Sbjct 958 RYILPNKSIATVVGP 972
>Q9LJL3 Presequence protease 1, chloroplastic/mitochondrial [Arabidopsis
thaliana]
Length=1080
Score = 390 bits (1003), Expect = 4e-122
Identities = 291/966 (30%), Positives = 469/966 (49%), Gaps = 65/966 (7%)
Query 17 FQLVRQHHVEALDILVSEYAHKVTGAVHYHLATSHDENVFLVAFRTQPMDSKGTAHILEH 76
F+ V + + + HK TG ++ + VF V FRT P DS G HILEH
Sbjct 107 FEKVSEEFISECKSKAILFKHKKTGCEVMSVSNEDENKVFGVVFRTPPKDSTGIPHILEH 166
Query 77 TALCGSEKFPVRDPFFLMIRRSLNTFMNAFTSADWTAYPFATQNKKDFQNLLSVYLDAAF 136
+ LCGS K+PV++PF +++ SL+TF+NAFT D T YP A+ N KDF NL+ VYLDA F
Sbjct 167 SVLCGSRKYPVKEPFVELLKGSLHTFLNAFTYPDRTCYPVASTNTKDFYNLVDVYLDAVF 226
Query 137 AANL--NPLDFAQEGIRIELEN-GEPV-YKGVVFNEMKGAMSAPSDQLYHQLAYHLFPET 192
+ F QEG EL + E + YKGVVFNEMKG S P + L L PE
Sbjct 227 FPKCVDDAHTFQQEGWHYELNDPSEDISYKGVVFNEMKGVYSQPDNILGRIAQQALSPEN 286
Query 193 TYHYNSGGDPKDIPDLSYEQLVDFYKSHYHPSNAVFMTFGNQNAYD----LQEQFEKLAL 248
TY +SGGDPKDIP+L++E+ +F++ +YHPSNA +G+ + L E +
Sbjct 287 TYGVDSGGDPKDIPNLTFEEFKEFHRQYYHPSNARIWFYGDDDPVHRLRVLSEYLDMFEA 346
Query 249 SKFEKGTTLYSKPEKRLATPIQVTETYAVDSEDLDDKTYHVLA--WLLPQAS-DIKLRLG 305
S + + K +K + P+++ E Y D D K H+L WLL + D++ +L
Sbjct 347 SPSPNSSKI--KFQKLFSEPVRLVEKYPA-GRDGDLKKKHMLCVNWLLSEKPLDLQTQLA 403
Query 306 LRLVEGILLENSASPLRHYLETCGYAQSTGPLMGVDDSNFEMTFYCGVQGSNAAHADEFR 365
L ++ ++L ASPLR L G ++ G+ D + F G++G + + +
Sbjct 404 LGFLDHLMLGTPASPLRKILLESGLGEAL-VSSGLSDELLQPQFGIGLKGVSEENVQKVE 462
Query 366 EGVLNILQQVASQPVDQALVDAILHQIELHQREINGDGMPYGLSLILNGLSSAIHHNDPV 425
E +++ L+++A + D V+A ++ IE RE N P GLSL+L +S I+ DP
Sbjct 463 ELIMDTLKKLAEEGFDNDAVEASMNTIEFSLRENNTGSFPRGLSLMLQSISKWIYDMDPF 522
Query 426 HVWDVDTAIEQVKEELKD---PMWLSNLIQTHLLDNPHRVQMTLVPDAEKSMKDQAEEKA 482
++ +K + + S LI+ +L+N HRV + + PD EK+ +++ EEK
Sbjct 523 EPLKYTEPLKALKTRIAEEGSKAVFSPLIEKLILNNSHRVTIEMQPDPEKATQEEVEEKN 582
Query 483 RLAEIGAHLTEEDRAQINANTEALNQRQDTPDD---LDLLPKVGLEDVPADLHIVQ---G 536
L ++ A +TEED A++ TE L +Q+TPD L +P + L D+P + V G
Sbjct 583 ILEKVKAAMTEEDLAELARATEELKLKQETPDPPEALRCVPSLNLGDIPKEPTYVPTEVG 642
Query 537 QLREIISNRHDYPLNLYHAGTNGIYYQQVLIEIPDEVVHS--PYFNLLSILMGEVGAGEY 594
+ + RHD TN I Y +V+ +I + H P L + E+G +
Sbjct 643 DINGVKVLRHD-------LFTNDIIYTEVVFDI-GSLKHELLPLVPLFCQSLLEMGTKDL 694
Query 595 DYLTLQQLQTAVSGGLGMGASLRSKVDDKNKISAWLTLTTKSLNEKRDAI-QLLKLAFEK 653
++ L QL +GG+ + L S V K++ + + + KS+ + D + L+ ++
Sbjct 695 TFVQLNQLIGRKTGGISV-YPLTSSVRGKDEPCSKIIVRGKSMAGRADDLFNLMNCLLQE 753
Query 654 LRFDEKDRIIELLQQRKTRWISRLSGSGHSYAMQIASRNMSALAQRDYHNTGLGALNWLS 713
++F ++ R + + Q + R +RL GSGH A ++ GL L +L
Sbjct 754 VQFTDQQRFKQFVSQSRARMENRLRGSGHGIAAARMDAMLNIAGWMSEQMGGLSYLEFLH 813
Query 714 NLVDQIEQDESAYDALIHELKAIHLKL------LQAPKQFLLVCEE---QFADALVEDIQ 764
L ++++D + + E++ L + A + L E+ +F D L E+
Sbjct 814 TLEKKVDEDWEGISSSLEEIRRSLLARNGCIVNMTADGKSLTNVEKSVAKFLDLLPENPS 873
Query 765 ---TVWD-HLEIESDVIEIQHLAQQNHNQDEAWLIQTNVQFCASAYPAVEVTHPDAAPLM 820
WD L + ++ I I Q N+ + T + SAY
Sbjct 874 GGLVTWDGRLPLRNEAIVIP--TQVNYVGKAGNIYSTGYELDGSAY-------------- 917
Query 821 VLAAYLRNGYLHSAIREKGGAYGGGASYDGNACSFRFYSYRDPRLAETFQDFEASIDWLL 880
V++ ++ N +L +R GGAYGG +D ++ F + SYRDP L +T ++ + D+L
Sbjct 918 VISKHISNTWLWDRVRVSGGAYGGFCDFDSHSGVFSYLSYRDPNLLKTLDIYDGTGDFLR 977
Query 881 HTSQQPHQLEEAILGLVSSMDKPGSPAGEAITACYALLHARTPAFRKTLRTRLLNVTLDD 940
L +AI+G + +D P + ++ L T R+ R +L +L D
Sbjct 978 GLDVDQETLTKAIIGTIGDVDSYQLPDAKGYSSLLRHLLGVTDEERQRKREEILTTSLKD 1037
Query 941 LKRVAQ 946
K AQ
Sbjct 1038 FKDFAQ 1043
>Q6CWW6 Presequence protease, mitochondrial [Kluyveromyces lactis
(strain ATCC 8585 / CBS 2359 / DSM 70799 / NBRC 1267 / NRRL
Y-1140 / WM37)]
Length=982
Score = 382 bits (981), Expect = 8e-120
Identities = 291/980 (30%), Positives = 466/980 (48%), Gaps = 65/980 (7%)
Query 13 VHPAFQLVRQHHVEALDILVSEYAHKVTGAVHYHLATSHDENVFLVAFRTQPMDSKGTAH 72
V +++ R V L + + H TG+ H H+ + NVF + F+T P DS G H
Sbjct 25 VFHGYEVKRLLPVPELKLTAVDLLHNQTGSQHLHIDRDDNNNVFSIGFKTNPPDSTGVPH 84
Query 73 ILEHTALCGSEKFPVRDPFFLMIRRSLNTFMNAFTSADWTAYPFATQNKKDFQNLLSVYL 132
ILEHT LCGS K+PVRDPFF M+ RSL FMNA T D+T YPFAT N+ DF NL VYL
Sbjct 85 ILEHTTLCGSHKYPVRDPFFKMLNRSLANFMNAMTGHDYTFYPFATTNETDFANLRDVYL 144
Query 133 DAAFAANLNPLDFAQEGIRIEL-----ENGEPVYKGVVFNEMKGAMSAPSDQLYHQLAYH 187
DA LN DF QEG R+E N + +KGVV+NEMKG +S + + +
Sbjct 145 DATLNPLLNQQDFLQEGWRLEHTKVDDPNSDIGFKGVVYNEMKGQVSNANYYFWIKFQES 204
Query 188 LFPETTYHYNSGGDPKDIPDLSYEQLVDFYKSHYHPSNAVFMTFGNQNAYDLQEQFEKLA 247
+P NSGGDP + DL YE L+ F++++YHPSNA T+GN +DL ++
Sbjct 205 YYPSLN---NSGGDPTKMTDLQYEDLISFHRNNYHPSNAKTFTYGN---FDLNNTLQR-- 256
Query 248 LSKFEKGTTLYSK--PEKRLATPIQVTETYAVDSEDL-------DDKTYHVLAWLLPQAS 298
L+K +G Y + +KR PIQ+ E +V++E D + + W+ +
Sbjct 257 LNKEYQG---YGRRGSKKRELLPIQMKEDVSVETEGQVDPMLPPDKQIKTSVTWICGKPE 313
Query 299 DIKLRLGLRLVEGILLENSASPLRHYLETCGYAQSTGPLMGVDDSNFEMTFYCGVQGSNA 358
D L+++ +LL+ +SP L G A GV+ GVQG +
Sbjct 314 DTYQTFLLKILGNLLLDGHSSPFYQKLIESGLAYDFSVNTGVESQTAANFITIGVQGCD- 372
Query 359 AHADEFREGVLNILQQVASQPVDQALVDAILHQIELHQREINGDGMPYGLSLILNGLSSA 418
D E + + ++V P +++ + AI+ Q+EL +++ D +GL L+ + L
Sbjct 373 -EVDSIYEVINKVWEEVLQNPFEESRIQAIIQQLELSKKDQRAD---FGLQLLYSVLPGW 428
Query 419 IHHNDPVHVWDVDTAIEQVKEE--LKDPMWLSNLIQTHLLDNPHRVQMTLVPDAEKSMKD 476
++ DP D +E+ +E+ K +LI+ ++ P + T+ S K
Sbjct 429 VNKTDPFDSLLFDETLERFQEDWATKGDNLFKDLIKEFVISKP-VFKFTMKGSETFSQKL 487
Query 477 QAEEKARLAEIGAHLTEEDRAQINANTEALNQRQDTPDDLDLLPKVGLEDVPADLHIVQG 536
AEE+ RL L EED+ I + L + QD +DL LP + + +P
Sbjct 488 DAEEQERLERKLKLLDEEDKKVIFERGKQLQELQDLKEDLSCLPSLQISAIPRVSKTYPL 547
Query 537 QLREIISNRHDYPLNLYHAGTNGIYY----QQVLIEIPDEVVHSPYFNLLSILMGEVGAG 592
++ + NR TNGI Y + + IP E+ P+ L + + +G
Sbjct 548 LEKDNVLNR--------ITDTNGITYVRGKRLLNHHIPRELY--PFLPLYADSLTNLGTS 597
Query 593 EYDYLTLQQLQTAVSGGLGMGASLRSKVDDKNKISAWLTLTTKSLNEKRDAIQLL--KLA 650
++ T+++ +GG+ S+ K + +LN K D I KL
Sbjct 598 TEEFSTIEEQIKLHTGGVSTRVSVNPDA-QTGKPMLLFQVDGWALNSKTDHIFKFWKKLL 656
Query 651 FEKLRFDEKDRIIELLQQRKTRWISRLSGSGHSYAMQIASRNMSALAQRDYHNTGLGALN 710
E K+++ L++ + + ++ +GH++A + ++S + G+ L
Sbjct 657 CETDFHKHKEKLKVLIRSLASSNTASVAETGHAFARNFGAAHLSVTKAINESLNGIEQLQ 716
Query 711 WLSNLVDQIEQDESAYDALIHELKAIHLKLL---QAPKQFLLVCEEQF-ADALVEDIQTV 766
L N + Q DE+ ++ + K + L+ + +F++ + Q DA+ + I
Sbjct 717 -LINKLSQCLDDEALFEKEVVS-KLVELQSYINGSSDMKFMITSDSQVQIDAVHQQITGF 774
Query 767 WDHLEIES---DVIEIQHLAQQNHNQDEAWLIQTNVQFCASAYPAVEVTHPDAAPLMVLA 823
L +S D + +N + V + A YP V THPD A L +L+
Sbjct 775 LSSLPKDSKPCDFYSENYSMLENPGKPTLLQFPFQVHYTAKCYPGVSYTHPDGAKLQILS 834
Query 824 AYLRNGYLHSAIREKGGAYGGGASYDGNACSFRFYSYRDPRLAETFQDFEASIDWLLHTS 883
L + YLH IREKGGAYGGGA+Y +F FYSYRDP + F++ +++L+ S
Sbjct 835 NMLTHKYLHREIREKGGAYGGGATYSALDGTFSFYSYRDPHALNSLSTFDSVPEFILNKS 894
Query 884 Q--QPHQLEEAILGLVSSMDKPGSPAGEAITACYALLHARTPAFRKTLRTRLLNVTLDDL 941
+P L EA L + +D P S E + + T ++ R +LL+V L+D+
Sbjct 895 SWGEP-DLNEAKLSVFQQVDSPMSAKNEGTILFH---YDVTDEMKQRRREQLLDVNLNDI 950
Query 942 KRVAQHYLQEQQVTRAVVAP 961
+VA+ YL++ + ++V P
Sbjct 951 HQVAEEYLKQDKSIASIVGP 970
>Q8K411 Presequence protease, mitochondrial [Mus musculus]
Length=1036
Score = 379 bits (974), Expect = 2e-118
Identities = 288/993 (29%), Positives = 457/993 (46%), Gaps = 78/993 (8%)
Query 9 INQTVHPAFQLVRQHHVEALDILVSEYAHKVTGAVHYHLATSHDENVFLVAFRTQPMDSK 68
+ + +H F + + V L + + +H TGA + HLA N+F V FRT PMDS
Sbjct 42 VGEKIH-GFTVNQVTPVPELFLTAVKLSHDNTGARYLHLAREDKNNLFSVQFRTTPMDST 100
Query 69 GTAHILEHTALCGSEKFPVRDPFFLMIRRSLNTFMNAFTSADWTAYPFATQNKKDFQNLL 128
G H+LEHT LCGS+K+P RDPFF M+ RSL+TFMNA T++D+T YPF+TQN KDFQNLL
Sbjct 101 GVPHVLEHTVLCGSQKYPCRDPFFKMLNRSLSTFMNAMTASDYTIYPFSTQNPKDFQNLL 160
Query 129 SVYLDAAFAANLNPLDFAQEGIRIELENGEP-----VYKGVVFNEMKGAMSAPSDQLYHQ 183
SVYLDA F L LDF QEG R+E EN ++KGVVFNEMKGA +
Sbjct 161 SVYLDATFFPCLRELDFWQEGWRLEHENPRDPQTPLIFKGVVFNEMKGAFTDNERIFSQH 220
Query 184 LAYHLFPETTYHYNSGGDPKDIPDLSYEQLVDFYKSHYHPSNAVFMTFGNQNAYDLQEQF 243
L L P+ TY SGGDP IP+L++EQL F+ +HYHPSNA F T+GN +Q
Sbjct 221 LQNKLLPDHTYSVVSGGDPLCIPELTWEQLKQFHATHYHPSNARFFTYGNFQLEGHLKQI 280
Query 244 EKLALSKF---EKGTTLYSKPEKRLATPIQVTETYAVDSEDLDDKTYHVLAWLLPQASDI 300
+ ALSKF E+ T + ++P +T + + +T +++LLP +D
Sbjct 281 HEEALSKFQRLEQSTAVPAQPHWDKPREFHITCGPDSLATETAKQTTVSVSFLLPDITDT 340
Query 301 KLRLGLRLVEGILLENSASPLRHYLETCGYAQSTGPLMGVDDSNFEMTFYCGVQGSNAAH 360
L L+ +L+ SP L G P +G + E F G+QG
Sbjct 341 FEAFTLSLLSSLLIAGPNSPFYKALIESGLGTDFSPDVGYNGYTREAYFSVGLQGIAEKD 400
Query 361 ADEFREGVLNILQQVASQPVDQALVDAILHQIELHQREINGDGMPYGLSLILNGLSSAIH 420
RE V +++V + + ++A+LH+IE+ + +GL+L S H
Sbjct 401 VKTVRELVDRTIEEVIEKGFEDDRIEALLHKIEIQTKH---QSASFGLTLTSYIASCWNH 457
Query 421 HNDPVHVWDVDTAIEQVKEELKD-PMWLSNLIQTHLLDNPHRVQMTLVPDAEKSMKDQAE 479
DPV + + + + + ++ LK+ P +L ++ + +N H++ +++ PD + K
Sbjct 458 DGDPVELLQIGSQLTRFRKCLKENPKFLQEKVEQYFKNNQHKLTLSMKPDDKYYEKQTQM 517
Query 480 EKARLAEIGAHLTEEDRAQINANTEALNQRQDTPDDLDLLPKVGLEDVPADLHIVQGQLR 539
E +L + L+ D+ QI L +Q D LP + + D+ + +
Sbjct 518 ETEKLEQKVNSLSPADKQQIYEKGLELQTQQSKHQDASCLPALKVSDIEPSMPFTK---L 574
Query 540 EIISNRHDYPLNLYHAGTNGIYYQQV---LIEIPDEVVHSPYFNLLSILMGEVGAGEYDY 596
+I D P+ TNG+ Y + L +P+++ P L ++ ++G G +Y
Sbjct 575 DIGLAAGDIPVQYCPQPTNGMVYFRAFSSLNTLPEDL--RPIVPLFCSVLTKLGCGILNY 632
Query 597 LTLQQLQTAVSGGLGMGASLRSKVDDKNKISAWLTLTTKSLNEK-RDAIQLLKLAFEKLR 655
Q +GG+ + + + + ++ L D + L F
Sbjct 633 REQAQQIELKTGGMSVTPHVLPDDSQLDTYEQGVLFSSLCLERNLPDMMHLWSEIFNNPC 692
Query 656 FDEKDRIIELLQQRKTRWISRLSGSGHSYAMQIASRNMSALAQRDYHNTGLGALNWLSNL 715
F+E++ L++ + +S SGH YA AS+ + T G L +
Sbjct 693 FEEEEHFKVLVKMTAQELSNGISDSGHLYAALRASKTL----------TPSGDLQETFSG 742
Query 716 VDQIEQDESAYDALIHELKAIHLKLLQAPKQFLLVCEEQFADALVEDIQTVWDHLEIESD 775
+DQ++ + A + ++K I L+ L K++LL C+ Q E+E+
Sbjct 743 MDQVKVMKRI--AEMTDIKPI-LRKLPRIKKYLLNCDNMRCSVNATPQQMPQAEKEVENF 799
Query 776 VIEI-----------QHLAQQNHNQDEA----------------------------WLIQ 796
+ + H+ ++ + +++
Sbjct 800 LRNVGRSKKERKPVRPHIVEKPTPSGPSGAAHVSGSQIVRKLVTDPTFKPCQMKTHFVLP 859
Query 797 TNVQFCASAYPAVEVTHPDAAPLMVLAAYLRNGYLHSAIREKGGAYGGGASYDGNACSFR 856
V + V PD A L +LA + +LH+ IREKGGAYGGGA + F
Sbjct 860 FPVNYIGECVRTVPYADPDHASLKILARLMTAKFLHTEIREKGGAYGGGAKLTHSGI-FT 918
Query 857 FYSYRDPRLAETFQDFEASIDWLLHTSQQPHQLEEAILGLVSSMDKPGSPAGEAITACYA 916
YSYRDP ET Q F ++DW ++EA L + S++D P +P+ + +
Sbjct 919 LYSYRDPNSIETLQSFGKAVDWAKSGKFTQQDIDEAKLSVFSTVDSPVAPSDKGMD---H 975
Query 917 LLHARTPAFRKTLRTRLLNVTLDDLKRVAQHYL 949
L+ + ++ R +L V D L V+ YL
Sbjct 976 FLYGLSDEMKQAYREQLFAVNHDKLTSVSHKYL 1008
>Q46205 Protein HypA [Clostridium perfringens (strain 13 / Type
A)]
Length=973
Score = 377 bits (969), Expect = 3e-118
Identities = 267/950 (28%), Positives = 479/950 (50%), Gaps = 37/950 (4%)
Query 13 VHPAFQLVRQHHVEALDILVSEYAHKVTGAVHYHLATSHDENVFLVAFRTQPMDSKGTAH 72
++ F+L+ ++ + + + H+ T A + + D F + FRT P +S G H
Sbjct 8 IYSGFKLLNIENLNEIGGVGLRFEHEKTKAKLIKILSEDDNKCFAIGFRTPPENSTGVPH 67
Query 73 ILEHTALCGSEKFPVRDPFFLMIRRSLNTFMNAFTSADWTAYPFATQNKKDFQNLLSVYL 132
ILEH+ LCGS KF ++PF +++ SLNTF+NA T D T YP A++N+KDF NL+ VYL
Sbjct 68 ILEHSVLCGSRKFNTKEPFVELLKGSLNTFLNAMTYPDKTIYPVASRNEKDFMNLMDVYL 127
Query 133 DAAFAANL--NPLDFAQEGIRIELENGEP--VYKGVVFNEMKGAMSAPSDQLYHQLAYHL 188
DA N+ + F QEG +EN E Y GVV+NEMKGA S+P LY ++ +
Sbjct 128 DAVLYPNIYKHKEIFMQEGWHYYIENKEDELKYNGVVYNEMKGAYSSPDSILYRKIPQTI 187
Query 189 FPETTYHYNSGGDPKDIPDLSYEQLVDFYKSHYHPSNAVFMTFGNQNAYDLQEQFEKLAL 248
+P+T Y +SGGDP +IP+L+YE+ V+F+K +YHPSN+ +GN + E + L
Sbjct 188 YPDTCYALSSGGDPDEIPNLTYEEFVEFHKKYYHPSNSYIFLYGNGDTEKELEFINEEYL 247
Query 249 SKFE-KGTTLYSKPEKRLATPIQVTETYAV-DSEDLDDKTYHVLAWLLPQASDIKLRLGL 306
FE K K +K + + + TY + +SEDL+ K+Y+ L +++ A+D + L
Sbjct 248 KNFEYKEIDSEIKEQKSFESMKEESFTYGIAESEDLNHKSYYSLNFVIGDATDGEKGLAF 307
Query 307 RLVEGILLENSASPLRHYLETCGYAQSTGPLMGVDDSNFEMTFYCGVQGSNAAHADEFRE 366
++ +L ++A+PL+ L G ++ D+S + F V+ + +EF++
Sbjct 308 DVLAYLLTRSTAAPLKKALIDAGIGKAVSG--DFDNSTKQSAFTVLVKNAELNKEEEFKK 365
Query 367 GVLNILQQVASQPVDQALVDAILHQIELHQREINGDGMPYGLSLILNGLSSAIHHNDPVH 426
V++ L+ + +D+ L++A ++++E RE + P GL L + S ++ DP
Sbjct 366 VVMDTLKDLVENGIDKELIEASINRVEFELREGDYGSYPNGLIYYLKVMDSWLYDGDPYV 425
Query 427 VWDVDTAIEQVKEELKDPMWLSNLIQTHLLDNPHRVQMTLVPDAEKSMKDQAEEKARLAE 486
+ + +E++K L + +LI+ ++++N H ++L P+ + K AE K +L E
Sbjct 426 HLEYEKNLEKIKSALTS-NYFEDLIERYMINNTHSSLVSLHPEKGINEKKSAELKKKLEE 484
Query 487 IGAHLTEEDRAQINANTEALNQRQDTPD---DLDLLPKVGLEDVPADLHIVQGQLREIIS 543
I E+ +I N + L +RQ TPD DL+ +P + LED+ + + + +EI
Sbjct 485 IKNSFDEKTLNEIIDNCKKLKERQSTPDKKEDLESIPMLSLEDIDKEATKIPTEEKEI-- 542
Query 544 NRHDYPLNLYH-AGTNGIYYQQVLI---EIPDEVVHSPYFNLLSILMGEVGAGEYDYLTL 599
D L+H TN I Y +P++++ PY LL ++G+ G YDY L
Sbjct 543 ---DGITTLHHDFHTNKIDYVNFFFNTNSVPEDLI--PYVGLLCDILGKCGTENYDYSKL 597
Query 600 QQLQTAVSGGLGMGASLRSKVDDKNKISAWLTLTTKSLNEKRD-AIQLLKLAFEKLRFDE 658
+GG+ GA + + N+ +L ++ K+L+ K + AI+L+ D+
Sbjct 598 SNAINISTGGISFGAITFANLKKNNEFRPYLEISYKALSSKTNKAIELVDEIVNHTDLDD 657
Query 659 KDRIIELLQQRKTRWISRLSGSGHSYAMQIASRNMSALAQRDYHNTGLGALNWLSNLVDQ 718
DRI++++++++ R + SGH AM+ + +S R ++ + L++ LV+
Sbjct 658 MDRIMQIIREKRARLEGAIFDSGHRIAMK---KVLSYSTNRGAYDEKISGLDYYDFLVNI 714
Query 719 IEQDESAYDALIHELKAIHLKLLQAPKQFLLVC-EEQFADALVEDIQTVWDHLEIESDVI 777
++D+ + + LK + + + +E+ + E ++ + + ++
Sbjct 715 EKEDKKS--TISDSLKKVRDLIFNKGNMLISYSGKEEEYENFKEKVKYLIS--KTNNNDF 770
Query 778 EIQHLAQQNHNQDEAWLIQTNVQFCASAYPAVEVTHPDAAPLMVLAAYLRNGYLHSAIRE 837
E + + ++E L Q NVQ+ A + + L +L + L YL +A+R
Sbjct 771 EKEEYNFELGKKNEGLLTQGNVQYVAKGGNYKTHGYKYSGALSLLESILGFDYLWNAVRV 830
Query 838 KGGAYGGGASY--DGNACSFRFYSYRDPRLAETFQDFEASIDWLLHTSQQPHQLEEAILG 895
KGGAYG +++ DG A SYRDP + T + ++ +L ++ + I+G
Sbjct 831 KGGAYGVFSNFRRDGGA---YIVSYRDPNIKSTLEAYDNIPKYLNDFEADEREMTKYIIG 887
Query 896 LVSSMDKPGSPAGEAITACYALLHARTPAFRKTLRTRLLNVTLDDLKRVA 945
+ D+P S + A L T + R ++N ++ +K A
Sbjct 888 TIRKYDQPISNGIKGDIAVSYYLSNFTYEDLQKEREEIINADVEKIKSFA 937
>P32898 Presequence protease, mitochondrial [Saccharomyces cerevisiae
(strain ATCC 204508 / S288c)]
Length=989
Score = 340 bits (872), Expect = 3e-104
Identities = 292/985 (30%), Positives = 455/985 (46%), Gaps = 96/985 (10%)
Query 25 VEALDILVSEYAHKVTGAVHYHLATSHDENVFLVAFRTQPMDSKGTAHILEHTALCGSEK 84
V L + + H TGA H H+ NVF +AF+T P DS G HILEHT LCGS K
Sbjct 37 VPELRLTAVDLVHSQTGAEHLHIDRDDKNNVFSIAFKTNPPDSTGVPHILEHTTLCGSVK 96
Query 85 FPVRDPFFLMIRRSLNTFMNAFTSADWTAYPFATQNKKDFQNLLSVYLDAAFAANLNPLD 144
+PVRDPFF M+ +SL FMNA T D+T +PF+T N +DF NL VYLD+ L D
Sbjct 97 YPVRDPFFKMLNKSLANFMNAMTGPDYTFFPFSTTNPQDFANLRGVYLDSTLNPLLKQED 156
Query 145 FAQEGIRIELEN-----GEPVYKGVVFNEMKGAMSAPSDQLYHQLAYHLFPETTYHYNSG 199
F QEG R+E +N V+KGVV+NEMKG +S + + + ++P NSG
Sbjct 157 FDQEGWRLEHKNITDPESNIVFKGVVYNEMKGQISNANYYFWSKFQQSIYPSLN---NSG 213
Query 200 GDPKDIPDLSYEQLVDFYKSHYHPSNAVFMTFGNQNAYDLQEQFEKLALSKFEKGTTLYS 259
GDP I DL Y L+DF+ +YHPSNA T+GN D +Q + S + K
Sbjct 214 GDPMKITDLRYGDLLDFHHKNYHPSNAKTFTYGNLPLVDTLKQLNE-QFSGYGKRAR--- 269
Query 260 KPEKRLATPIQVTETYAVDSEDLDD-------KTYHVLAWLLPQASDIKLRLGLRLVEGI 312
+ +L PI + + V D +T + W+ D L+++ +
Sbjct 270 --KDKLLMPIDLKKDIDVKLLGQIDTMLPPEKQTKASMTWICGAPQDTYDTFLLKVLGNL 327
Query 313 LLENSASPLRHYLETCGYAQSTGPLMGVDDSNFEMTFYCGVQGSNAAHADEFREGVLNIL 372
L++ +S + L G GV+ + G+QG + + F++ V NI
Sbjct 328 LMDGHSSVMYQKLIESGIGLEFSVNSGVEPTTAVNLLTVGIQG--VSDIEIFKDTVNNIF 385
Query 373 QQV--ASQPVDQALVDAILHQIELHQREINGDGMPYGLSLILNGLSSAIHHNDPVHVWDV 430
Q + P D+ +DAI+ Q+EL +++ D +GL L+ + L + DP
Sbjct 386 QNLLETEHPFDRKRIDAIIEQLELSKKDQKAD---FGLQLLYSILPGWTNKIDPFESLLF 442
Query 431 DTAIEQVKEEL--KDPMWLSNLIQTHLLDNP-HRVQMTLVPDAEKSMKDQAEEKARLAEI 487
+ +++ + +L K +LI+ +++ P + + KS+ D EE+ RL E
Sbjct 443 EDVLQRFRGDLETKGDTLFQDLIRKYIVHKPCFTFSIQGSEEFSKSLDD--EEQTRLREK 500
Query 488 GAHLTEEDRAQINANTEALNQRQDTPDDLDLLPKVGLEDVP--ADLHIVQGQLREIISNR 545
L E+D+ I L ++Q+ +DL LP + ++D+P D + ++ Q +S
Sbjct 501 ITALDEQDKKNIFKRGILLQEKQNEKEDLSCLPTLQIKDIPRAGDKYSIE-QKNNTMSRI 559
Query 546 HDYPLNLYHAGTNGIYY---QQVLIE-IPDEVVHSPYFNLLSILMGEVGAGEYDYLTLQQ 601
D TNGI Y +++L + IP E+ PY L + + +G + ++
Sbjct 560 TD---------TNGITYVRGKRLLNDIIPFELF--PYLPLFAESLTNLGTTTESFSEIED 608
Query 602 LQTAVSGGLGMGASLRSKVDDKNKISAWLTLTTK--SLNEKRDAI------QLLKLAFEK 653
+GG+ + S D N L SLN K D I LL+ F K
Sbjct 609 QIKLHTGGISTHVEVTS---DPNTTEPRLIFGFDGWSLNSKTDHIFEFWSKILLETDFHK 665
Query 654 LRFDEKDRIIELLQQRKTRWISRLSGSGHSYAMQIASRNMSALAQRDYHNTGLGALNWLS 713
D+ +I LL T S ++ +GH++A R SA H GA+N
Sbjct 666 -NSDKLKVLIRLLASSNT---SSVADAGHAFA-----RGYSAA-----HYRSSGAINETL 711
Query 714 NLVDQIEQDESAYDALIHE---LKAIHLKLLQAPKQFLLVCEEQFADALVEDIQTVWDHL 770
N ++Q++ + L +E + + KL + K + F D+Q
Sbjct 712 NGIEQLQFINRLHSLLDNEETFQREVVDKLTELQKYIVDTNNMNFFITSDSDVQAKTVES 771
Query 771 EIESDVIEIQH---LAQQNHNQDEAWL----------IQTNVQFCASAYPAVEVTHPDAA 817
+I + + H L D + V + + A V TH D +
Sbjct 772 QISKFMERLPHGSCLPNGPKTSDYPLIGSKCKHTLIKFPFQVHYTSQALLGVPYTHKDGS 831
Query 818 PLMVLAAYLRNGYLHSAIREKGGAYGGGASYDGNACSFRFYSYRDPRLAETFQDFEASID 877
L V++ L +LH +REKGGAYGGGASY A F FYSYRDP+ ++ + F+ S
Sbjct 832 ALQVMSNMLTFKHLHREVREKGGAYGGGASYSALAGIFSFYSYRDPQPLKSLETFKNSGR 891
Query 878 WLLHTSQ-QPHQLEEAILGLVSSMDKPGSPAGEAITACYALLHARTPAFRKTLRTRLLNV 936
++L+ ++ L+EA L + +D P SP GE +T + T ++ R +LL+V
Sbjct 892 YILNDAKWGVTDLDEAKLTIFQQVDAPKSPKGEGVT---YFMSGVTDDMKQARREQLLDV 948
Query 937 TLDDLKRVAQHYLQEQQVTRAVVAP 961
+L D+ RVA+ YL ++ V+ P
Sbjct 949 SLLDVHRVAEKYLLNKEGVSTVIGP 973
>A0A0L7KF24 Falcilysin [Plasmodium falciparum (isolate HB3)]
Length=1193
Score = 240 bits (612), Expect = 3e-68
Identities = 245/1099 (22%), Positives = 448/1099 (41%), Gaps = 180/1099 (16%)
Query 14 HPAFQLVRQHHVEALDILVSEYAHKVTGAVHYHLATSHD---ENVFLVAFRTQPMDSKGT 70
H ++ ++ + + E + + Y HK L T+ E F +T KG
Sbjct 68 HNSYDIIEKRYNEEFKMTYTVYQHKKAKTQVISLGTNDPLDVEQAFAFYVKTLTHSGKGI 127
Query 71 AHILEHTALCGSEKFPVRDPFFLMIRRSLNTFMNAFTSADWTAYPFATQNKKDFQNLLSV 130
HILEH+ L GS+ + ++ L+ + +L+T +NA+T D T Y + N KDF N++ V
Sbjct 128 PHILEHSVLSGSKNYNYKNSIGLLEKGTLHTHLNAYTFNDRTVYMAGSMNNKDFFNIMGV 187
Query 131 YLDAAFAANL--NPLDFAQEGIRIELE----------------NGEPVYKGVVFNEMKGA 172
Y+D+ F N+ N F EG E+E + + + G+V+NEMKGA
Sbjct 188 YMDSVFQPNVLENKYIFETEGWTYEVEKLKEDEKGKAEIPQMKDYKVSFNGIVYNEMKGA 247
Query 173 MSAPSDQLYHQLAYHLFPETTYHYNSGGDPKDIPDLSYEQLVDFYKSHYHPSNAVFMTFG 232
+S+P + LYH+ ++FP+ + NSGGDPK+I +L+YE+ +FY +Y+P F
Sbjct 248 LSSPLEDLYHEEMKYMFPDNVHSNNSGGDPKEITNLTYEEFKEFYYKNYNPKKVKVFFFS 307
Query 233 NQNAYDL----QEQFEKLALSKFEKGTTLYSKPEKRLATPIQVTETYAVDSEDLDDKTYH 288
N +L + +L SK+ + + P + + Y SE+ ++
Sbjct 308 KNNPTELLNFVDQYLGQLDYSKYRDDAVESVEYQTYKKGPFYIKKKYGDHSEEKENLV-- 365
Query 289 VLAWLL----------------------------PQASDIKLR-----LGLRLVEGILLE 315
+AWLL +SD+ L L ++ +L+
Sbjct 366 SVAWLLNPKVDKTNNHNNNHSNNQSSENNGYSNGSHSSDLSLENPTDYFVLLIINNLLIH 425
Query 316 NSASPLRHYLETCGYAQSTGPLMGVDDSNFEMTFYCGVQGSNAAHAD---------EFRE 366
S L L CG + G++DS + F G++G + E +
Sbjct 426 TPESVLYKALTDCGLGNNVID-RGLNDSLVQYIFSIGLKGIKRNNEKIKIFDKVHYEVED 484
Query 367 GVLNILQQVASQPVDQALVDAILHQIELHQREINGDGMPYGLSLILNGLSSAIHHNDPVH 426
++N L++V + +++ V+A ++ IE +E N + + S ++ DP+
Sbjct 485 VIMNALKKVVKEGFNKSAVEASINNIEFILKEANLK-TSKSIDFVFEMTSKLNYNRDPLL 543
Query 427 VWDVDTAIEQVKEELK-DPMWLSNLIQTHLLDNPHRVQMTLVPDAEKSMKDQAEEKARLA 485
+++ + + VK ++K +PM+L ++ H ++N HR + L D + + + EK L
Sbjct 544 IFEFEKYLNIVKNKIKNEPMYLEKFVEKHFINNAHRSVILLEGDENYAQEQENLEKQELK 603
Query 486 EIGAHLTEEDRAQINANTEALNQ---RQDTPDDLDLLPKVGLED-------VPADLHI-- 533
+ + E+++ Q+ N E L++ +++P+ L+ P + + D VP +++
Sbjct 604 KRIENFNEQEKEQVIKNFEELSKYKNAEESPEHLNKFPIISISDLNKKTLEVPVNVYFTN 663
Query 534 ------VQGQLREIISNRH--------------------------------DY------- 548
+ ++ +N H DY
Sbjct 664 INENNNIMETYNKLKTNEHMLKDNMDVFLKKYVLKNDKHNTNNNNNNNNNMDYSFTETKY 723
Query 549 ----PLNLYHAGTNGIYYQQVLIEIPDEVVHS-PYFNLLSILMGEVGAGEYDYLTLQQLQ 603
P+ +Y T GI Y Q + + V Y NL L+ E + L+
Sbjct 724 EGNVPILVYEMPTTGIVYLQFVFSLDHLTVDELAYLNLFKTLILENKTNKRSSEDFVILR 783
Query 604 TAVSGGLGMGASLRSK-----VDDKNKISAWLTLTTKSLNEK-RDAIQLLKLAFEKLRFD 657
G + +L SK V DK A L L+ K DA+ + A ++ F
Sbjct 784 EKNIGSMSANVALYSKDDHLNVTDKYNAQALFNLEMHVLSHKCNDALNIALEAVKESDFS 843
Query 658 EKDRIIELLQQRKTRWISRLSGSGHSYAMQIASRNMSALAQRDYHNTGLGALNWLSNLVD 717
K ++I++L+++ + S G++ M+ +++ ++ HN G N+L L +
Sbjct 844 NKKKVIDILKRKINGMKTTFSEKGYAILMKYVKAHLN--SKHYAHNIIYGYENYL-KLQE 900
Query 718 QIEQDESAYDALIHELKAIHLKLLQAPKQFLLVCEEQFA--------------------- 756
Q+E E+ + L + L I K+ + V + A
Sbjct 901 QLELAENDFKTLENILVRIRNKIFNKKNLMVSVTSDYGALKHLFVNSNESLKNLVSYFEE 960
Query 757 -DALVEDIQTVWDHLEIE--SDVIEIQHLAQQNHNQDEAWLIQT---NVQFCASAYPAVE 810
D + D+Q + + ++ I+ + L + + E +++ T +V + E
Sbjct 961 NDKYINDMQNKVNDPTVMGWNEEIKSKKLFDEEKVKKEFFVLPTFVNSVSMSGILFKPGE 1020
Query 811 VTHPDAAPLMVLAAYLRNGYLHSAIREKGGAYG--GGASYDGNACSFRFYSYRDPRLAET 868
P V+ A L+N YL +R GAYG YDG S F S RDP L +T
Sbjct 1021 YLDPS---FTVIVAALKNSYLWDTVRGLNGAYGVFADIEYDG---SVVFLSARDPNLEKT 1074
Query 869 FQDFEASIDWL--LHTSQQPHQLEEAILGLVSSMDKPGSPAGEAITACYALLHARTPAFR 926
F S L + + + L I+ + ++DKP + + L+ + R
Sbjct 1075 LATFRESAKGLRKMADTMTENDLLRYIINTIGTIDKPRRGIELSKLSFLRLISNESEQDR 1134
Query 927 KTLRTRLLNVTLDDLKRVA 945
R R++N +D + A
Sbjct 1135 VEFRKRIMNTKKEDFYKFA 1153
>Q76NL8 Falcilysin [Plasmodium falciparum (isolate 3D7)]
Length=1193
Score = 240 bits (612), Expect = 3e-68
Identities = 245/1099 (22%), Positives = 448/1099 (41%), Gaps = 180/1099 (16%)
Query 14 HPAFQLVRQHHVEALDILVSEYAHKVTGAVHYHLATSHD---ENVFLVAFRTQPMDSKGT 70
H ++ ++ + + E + + Y HK L T+ E F +T KG
Sbjct 68 HNSYDIIEKRYNEEFKMTYTVYQHKKAKTQVISLGTNDPLDVEQAFAFYVKTLTHSGKGI 127
Query 71 AHILEHTALCGSEKFPVRDPFFLMIRRSLNTFMNAFTSADWTAYPFATQNKKDFQNLLSV 130
HILEH+ L GS+ + ++ L+ + +L+T +NA+T D T Y + N KDF N++ V
Sbjct 128 PHILEHSVLSGSKNYNYKNSIGLLEKGTLHTHLNAYTFNDRTVYMAGSMNNKDFFNIMGV 187
Query 131 YLDAAFAANL--NPLDFAQEGIRIELE----------------NGEPVYKGVVFNEMKGA 172
Y+D+ F N+ N F EG E+E + + + G+V+NEMKGA
Sbjct 188 YMDSVFQPNVLENKYIFETEGWTYEVEKLKEDEKGKAEIPQMKDYKVSFNGIVYNEMKGA 247
Query 173 MSAPSDQLYHQLAYHLFPETTYHYNSGGDPKDIPDLSYEQLVDFYKSHYHPSNAVFMTFG 232
+S+P + LYH+ ++FP+ + NSGGDPK+I +L+YE+ +FY +Y+P F
Sbjct 248 LSSPLEDLYHEEMKYMFPDNVHSNNSGGDPKEITNLTYEEFKEFYYKNYNPKKVKVFFFS 307
Query 233 NQNAYDL----QEQFEKLALSKFEKGTTLYSKPEKRLATPIQVTETYAVDSEDLDDKTYH 288
N +L + +L SK+ + + P + + Y SE+ ++
Sbjct 308 KNNPTELLNFVDQYLGQLDYSKYRDDAVESVEYQTYKKGPFYIKKKYGDHSEEKENLV-- 365
Query 289 VLAWLL----------------------------PQASDIKLR-----LGLRLVEGILLE 315
+AWLL +SD+ L L ++ +L+
Sbjct 366 SVAWLLNPKVDKTNNHNNNHSNNQSSENNGYSNGSHSSDLSLENPTDYFVLLIINNLLIH 425
Query 316 NSASPLRHYLETCGYAQSTGPLMGVDDSNFEMTFYCGVQGSNAAHAD---------EFRE 366
S L L CG + G++DS + F G++G + E +
Sbjct 426 TPESVLYKALTDCGLGNNVID-RGLNDSLVQYIFSIGLKGIKRNNEKIKNFDKVHYEVED 484
Query 367 GVLNILQQVASQPVDQALVDAILHQIELHQREINGDGMPYGLSLILNGLSSAIHHNDPVH 426
++N L++V + +++ V+A ++ IE +E N + + S ++ DP+
Sbjct 485 VIMNALKKVVKEGFNKSAVEASINNIEFILKEANLK-TSKSIDFVFEMTSKLNYNRDPLL 543
Query 427 VWDVDTAIEQVKEELK-DPMWLSNLIQTHLLDNPHRVQMTLVPDAEKSMKDQAEEKARLA 485
+++ + + VK ++K +PM+L ++ H ++N HR + L D + + + EK L
Sbjct 544 IFEFEKYLNIVKNKIKNEPMYLEKFVEKHFINNAHRSVILLEGDENYAQEQENLEKQELK 603
Query 486 EIGAHLTEEDRAQINANTEALNQ---RQDTPDDLDLLPKVGLED-------VPADLHI-- 533
+ + E+++ Q+ N E L++ +++P+ L+ P + + D VP +++
Sbjct 604 KRIENFNEQEKEQVIKNFEELSKYKNAEESPEHLNKFPIISISDLNKKTLEVPVNVYFTN 663
Query 534 ------VQGQLREIISNRH--------------------------------DY------- 548
+ ++ +N H DY
Sbjct 664 INENNNIMETYNKLKTNEHMLKDNMDVFLKKYVLKNDKHNTNNNNNNNNNMDYSFTETKY 723
Query 549 ----PLNLYHAGTNGIYYQQVLIEIPDEVVHS-PYFNLLSILMGEVGAGEYDYLTLQQLQ 603
P+ +Y T GI Y Q + + V Y NL L+ E + L+
Sbjct 724 EGNVPILVYEMPTTGIVYLQFVFSLDHLTVDELAYLNLFKTLILENKTNKRSSEDFVILR 783
Query 604 TAVSGGLGMGASLRSK-----VDDKNKISAWLTLTTKSLNEK-RDAIQLLKLAFEKLRFD 657
G + +L SK V DK A L L+ K DA+ + A ++ F
Sbjct 784 EKNIGSMSANVALYSKDDHLNVTDKYNAQALFNLEMHVLSHKCNDALNIALEAVKESDFS 843
Query 658 EKDRIIELLQQRKTRWISRLSGSGHSYAMQIASRNMSALAQRDYHNTGLGALNWLSNLVD 717
K ++I++L+++ + S G++ M+ +++ ++ HN G N+L L +
Sbjct 844 NKKKVIDILKRKINGMKTTFSEKGYAILMKYVKAHLN--SKHYAHNIIYGYENYL-KLQE 900
Query 718 QIEQDESAYDALIHELKAIHLKLLQAPKQFLLVCEEQFA--------------------- 756
Q+E E+ + L + L I K+ + V + A
Sbjct 901 QLELAENDFKTLENILVRIRNKIFNKKNLMVSVTSDYGALKHLFVNSNESLKNLVSYFEE 960
Query 757 -DALVEDIQTVWDHLEIE--SDVIEIQHLAQQNHNQDEAWLIQT---NVQFCASAYPAVE 810
D + D+Q + + ++ I+ + L + + E +++ T +V + E
Sbjct 961 NDKYINDMQNKVNDPTVMGWNEEIKSKKLFDEEKVKKEFFVLPTFVNSVSMSGILFKPGE 1020
Query 811 VTHPDAAPLMVLAAYLRNGYLHSAIREKGGAYG--GGASYDGNACSFRFYSYRDPRLAET 868
P V+ A L+N YL +R GAYG YDG S F S RDP L +T
Sbjct 1021 YLDPS---FTVIVAALKNSYLWDTVRGLNGAYGVFADIEYDG---SVVFLSARDPNLEKT 1074
Query 869 FQDFEASIDWL--LHTSQQPHQLEEAILGLVSSMDKPGSPAGEAITACYALLHARTPAFR 926
F S L + + + L I+ + ++DKP + + L+ + R
Sbjct 1075 LATFRESAKGLRKMADTMTENDLLRYIINTIGTIDKPRRGIELSKLSFLRLISNESEQDR 1134
Query 927 KTLRTRLLNVTLDDLKRVA 945
R R++N +D + A
Sbjct 1135 VEFRKRIMNTKKEDFYKFA 1153
>O22941 Insulin-degrading enzyme-like 1, peroxisomal [Arabidopsis
thaliana]
Length=970
Score = 42.0 bits (97), Expect = 3e-06
Identities = 50/193 (26%), Positives = 78/193 (40%), Gaps = 24/193 (12%)
Query 62 TQPMDSKGTAHILEHTALCGSEKFPVRDPFFLMIRRSLNTFMNAFTSADWTAYPFATQNK 121
+ P +G AH LEH SEK+P D + I + NA+T+++ T Y F N
Sbjct 59 SDPQGLEGLAHFLEHMLFYASEKYPEEDSYSKYITEHGGS-TNAYTASEETNYHFDV-NA 116
Query 122 KDFQNLLSVYLDAAFAANLNPLDFAQEGIRIELENGEPVYKGVVFNEMKGAMSAPSDQLY 181
F L + A F + PL A +R K V K +S
Sbjct 117 DCFDEALDRF--AQFF--IKPLMSADATMR--------EIKAVDSENQKNLLS--DGWRI 162
Query 182 HQLAYHLFPET-TYHYNSGGD-------PKDIPDLSYEQLVDFYKSHYHPSNAVFMTFGN 233
QL HL E YH S G+ P+ + +L+ FY+ HY + + +G
Sbjct 163 RQLQKHLSKEDHPYHKFSTGNMDTLHVRPQAKGVDTRSELIKFYEEHYSANIMHLVVYGK 222
Query 234 QNAYDLQEQFEKL 246
++ +Q+ E++
Sbjct 223 ESLDKIQDLVERM 235
>P11913 Mitochondrial-processing peptidase subunit beta [Neurospora
crassa (strain ATCC 24698 / 74-OR23-1A / CBS 708.71 /
DSM 1257 / FGSC 987)]
Length=476
Score = 41.6 bits (96), Expect = 3e-06
Identities = 47/187 (25%), Positives = 80/187 (43%), Gaps = 20/187 (11%)
Query 61 RTQPMDSKGTAHILEHTALCGSEKFPVRDPFFLMIRRSLNTFMNAFTSADWTAYPFATQN 120
R + ++ GTAH LEH A G+ K + L I ++ +NA+TS + T Y FA
Sbjct 73 RAETDETNGTAHFLEHLAFKGTTK-RTQQQLELEI-ENMGAHLNAYTSRENTVY-FAKAL 129
Query 121 KKDFQNLLSVYLDAAFAANL--NPLDFAQEGIRIELENGEPVYKGVVFNEMKGAMSAPSD 178
+D + + D + L + ++ ++ I E E E + VVF+ +
Sbjct 130 NEDVPKCVDILQDILQNSKLEESAIERERDVILRESEEVEKQLEEVVFDHL--------- 180
Query 179 QLYHQLAYHLFPETTYHYNSGGDPKDIPDLSYEQLVDFYKSHYHPSNAVFMTFGNQNAYD 238
H AY P G ++I D++ +LV++ K++Y V + G
Sbjct 181 ---HATAYQHQP---LGRTILGPRENIRDITRTELVNYIKNNYTADRMVLVGAGGVPHEQ 234
Query 239 LQEQFEK 245
L E +K
Sbjct 235 LVEMADK 241
>Q40983 Stromal processing peptidase, chloroplastic [Pisum sativum]
Length=1257
Score = 37.4 bits (85), Expect = 8e-05
Identities = 45/170 (26%), Positives = 72/170 (42%), Gaps = 20/170 (12%)
Query 66 DSKGTAHILEHTALCGSEKFPVRDPFFLMIRRSLNTFMNAFTSADWTAYPF-ATQNKKDF 124
D +G AH++EH A GS+K R+ RS NA+T T + + + KD
Sbjct 230 DEQGIAHMIEHVAFLGSKK---REKLLGTGARS-----NAYTDFHHTVFHIHSPTSTKDS 281
Query 125 QNLLSVYLDAAFAANLNPLDFAQEGIRIELENGEPVYKGVVFNEMKGAMSAPSDQLYHQL 184
+LL LDA +P A RIE E + + +E++ M+ ++ QL
Sbjct 282 DDLLPSVLDALNEITFHPNFLAS---RIEKE------RRAILSELQ-MMNTIEYRVDCQL 331
Query 185 AYHLFPETTYHYNSG-GDPKDIPDLSYEQLVDFYKSHYHPSNAVFMTFGN 233
HL E G + I +++ F++ Y P+NA G+
Sbjct 332 LQHLHSENKLSKRFPIGLEEQIKKWDADKIRKFHERWYFPANATLYIVGD 381
Score = 22.7 bits (47), Expect = 2.3
Identities = 22/94 (23%), Positives = 37/94 (39%), Gaps = 4/94 (4%)
Query 48 ATSHDENVFLVAFRTQPMD-SKGTAHILEHTALCGSEKFPVRDPFF---LMIRRSLNTFM 103
A V+L +R+ P + TAH L L G E+F P L ++ + M
Sbjct 875 ALDRARQVYLSYYRSIPKSLERSTAHKLMVAMLDGDERFTEPTPSSLENLTLQSVKDAVM 934
Query 104 NAFTSADWTAYPFATQNKKDFQNLLSVYLDAAFA 137
N F + +++ ++ + YL A A
Sbjct 935 NQFVGNNMEVSIVGDFTEEEIESCILDYLGTAQA 968
Lambda K H a alpha
0.319 0.134 0.392 0.792 4.96
Gapped
Lambda K H a alpha sigma
0.267 0.0410 0.140 1.90 42.6 43.6
Effective search space used: 15728850
Database: 6f495b21362f9785467239be772260cd.SwissProt.fasta
Posted date: May 19, 2024 9:03 PM
Number of letters in database: 18,360
Number of sequences in database: 18
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Neighboring words threshold: 11
Window for multiple hits: 40
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Data ...
