BLASTP 2.12.0+
Reference: Stephen F. Altschul, Thomas L. Madden, Alejandro A.
Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J.
Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of
protein database search programs", Nucleic Acids Res. 25:3389-3402.
Reference for composition-based statistics: Alejandro A. Schaffer,
L. Aravind, Thomas L. Madden, Sergei Shavirin, John L. Spouge, Yuri
I. Wolf, Eugene V. Koonin, and Stephen F. Altschul (2001),
"Improving the accuracy of PSI-BLAST protein database searches with
composition-based statistics and other refinements", Nucleic Acids
Res. 29:2994-3005.
Database: f2078f6338c6c800f90f1847edbe29af.SwissProt.fasta
15 sequences; 6,185 total letters
Query= ACIAD1412
Length=402
Score E
Sequences producing significant alignments: (Bits) Value
A5A6I0 Medium-chain specific acyl-CoA dehydrogenase, mitochondria... 186 4e-58
P11310 Medium-chain specific acyl-CoA dehydrogenase, mitochondria... 186 4e-58
Q3SZB4 Medium-chain specific acyl-CoA dehydrogenase, mitochondria... 184 3e-57
P45952 Medium-chain specific acyl-CoA dehydrogenase, mitochondria... 183 8e-57
P08503 Medium-chain specific acyl-CoA dehydrogenase, mitochondria... 182 1e-56
Q8HXY8 Medium-chain specific acyl-CoA dehydrogenase, mitochondria... 181 4e-56
P41367 Medium-chain specific acyl-CoA dehydrogenase, mitochondria... 178 4e-55
P15651 Short-chain specific acyl-CoA dehydrogenase, mitochondrial... 177 7e-55
Q07417 Short-chain specific acyl-CoA dehydrogenase, mitochondrial... 177 1e-54
Q9VSA3 Medium-chain specific acyl-CoA dehydrogenase, mitochondria... 177 2e-54
Q5RAS0 Short-chain specific acyl-CoA dehydrogenase, mitochondrial... 176 2e-54
O34421 Probable acyl-CoA dehydrogenase YngJ [Bacillus subtilis (s... 174 5e-54
P16219 Short-chain specific acyl-CoA dehydrogenase, mitochondrial... 175 5e-54
Q3ZBF6 Short-chain specific acyl-CoA dehydrogenase, mitochondrial... 175 7e-54
P45867 Acyl-CoA dehydrogenase [Bacillus subtilis (strain 168)] 172 2e-53
>A5A6I0 Medium-chain specific acyl-CoA dehydrogenase, mitochondrial
[Pan troglodytes]
Length=421
Score = 186 bits (473), Expect = 4e-58
Identities = 131/389 (34%), Positives = 192/389 (49%), Gaps = 31/389 (8%)
Query 16 AHDVALNVLRPISRKYDKAEHAYPKELDMLASLIDGMNEGGDGINAGATGAGKRGENEQQ 75
A A + P++ +YDK YP L A + MN N G G G
Sbjct 52 ARKFAREEIIPVAAEYDKTGE-YPVPLIRRAWELGLMNTHIPE-NCGGLGLG-------- 101
Query 76 GIRNGTNMSTALGIIEMCYGDTGLLLSMPRQGLGNSAIAAVANDEQLERFKGTWA----- 130
L E+ YG TG+ ++ LG I ND+Q +++ G
Sbjct 102 ------TFDACLISEELAYGCTGVQTAIEGNSLGQMPIIIAGNDQQKKKYLGRMTEEPLM 155
Query 131 -AMAITEPGCGSDSAAIRTTAVKAGDEYILNGEKIYVTSGERADSVVVWATLD---RKLG 186
A +TEPG GSD A I+T A K GDEYI+NG+K+++T+G +A+ + A D +
Sbjct 156 CAYCVTEPGAGSDVAGIKTKAEKKGDEYIINGQKMWITNGGKANWYFLLARSDPDPKAPA 215
Query 187 RAAIKSFVVPKGTPGMKVERLEHKLGIKASDTAAISFIDCRVPAANLLGNAEIDVAKGFA 246
A F+V TPG+++ R E +G + SDT I F D +VP N+L I GF
Sbjct 216 NKAFTGFIVEADTPGIQIGRKELNMGQRCSDTRGIVFEDVKVPRENVL----IGDGAGFK 271
Query 247 GVMETFDNTRPLVAAMAVGCAKASLERIKEIFKDELDTDYATPYLQTSFIAAQIYRMEAE 306
M FD TRP+VAA AVG A+ +L+ + + + ++ I+ + M +
Sbjct 272 VAMGAFDKTRPVVAAGAVGLAQRALDEATKYALER--KTFGKLLVEHQAISFMLAEMAMK 329
Query 307 WEAARLLTLKATWMADNKKPNSKEASIAKAKAGRICNEITLKCVELAASVGYNEDELLEK 366
E AR+ +A W D+ + N+ ASIAKA AG I N++ V++ G+N + +EK
Sbjct 330 VELARMSYQRAAWEVDSGRRNTYYASIAKAFAGDIANQLATDAVQILGGNGFNTEYPVEK 389
Query 367 WARDSKILDIFEGTQQIQLLIIARRELGK 395
RD+KI I+EGT QIQ LI+AR + K
Sbjct 390 LMRDAKIYQIYEGTSQIQRLIVAREHIDK 418
>P11310 Medium-chain specific acyl-CoA dehydrogenase, mitochondrial
[Homo sapiens]
Length=421
Score = 186 bits (473), Expect = 4e-58
Identities = 131/389 (34%), Positives = 192/389 (49%), Gaps = 31/389 (8%)
Query 16 AHDVALNVLRPISRKYDKAEHAYPKELDMLASLIDGMNEGGDGINAGATGAGKRGENEQQ 75
A A + P++ +YDK YP L A + MN N G G G
Sbjct 52 ARKFAREEIIPVAAEYDKTGE-YPVPLIRRAWELGLMNTHIPE-NCGGLGLG-------- 101
Query 76 GIRNGTNMSTALGIIEMCYGDTGLLLSMPRQGLGNSAIAAVANDEQLERFKGTWA----- 130
L E+ YG TG+ ++ LG I ND+Q +++ G
Sbjct 102 ------TFDACLISEELAYGCTGVQTAIEGNSLGQMPIIIAGNDQQKKKYLGRMTEEPLM 155
Query 131 -AMAITEPGCGSDSAAIRTTAVKAGDEYILNGEKIYVTSGERADSVVVWATLD---RKLG 186
A +TEPG GSD A I+T A K GDEYI+NG+K+++T+G +A+ + A D +
Sbjct 156 CAYCVTEPGAGSDVAGIKTKAEKKGDEYIINGQKMWITNGGKANWYFLLARSDPDPKAPA 215
Query 187 RAAIKSFVVPKGTPGMKVERLEHKLGIKASDTAAISFIDCRVPAANLLGNAEIDVAKGFA 246
A F+V TPG+++ R E +G + SDT I F D +VP N+L I GF
Sbjct 216 NKAFTGFIVEADTPGIQIGRKELNMGQRCSDTRGIVFEDVKVPKENVL----IGDGAGFK 271
Query 247 GVMETFDNTRPLVAAMAVGCAKASLERIKEIFKDELDTDYATPYLQTSFIAAQIYRMEAE 306
M FD TRP+VAA AVG A+ +L+ + + + ++ I+ + M +
Sbjct 272 VAMGAFDKTRPVVAAGAVGLAQRALDEATKYALER--KTFGKLLVEHQAISFMLAEMAMK 329
Query 307 WEAARLLTLKATWMADNKKPNSKEASIAKAKAGRICNEITLKCVELAASVGYNEDELLEK 366
E AR+ +A W D+ + N+ ASIAKA AG I N++ V++ G+N + +EK
Sbjct 330 VELARMSYQRAAWEVDSGRRNTYYASIAKAFAGDIANQLATDAVQILGGNGFNTEYPVEK 389
Query 367 WARDSKILDIFEGTQQIQLLIIARRELGK 395
RD+KI I+EGT QIQ LI+AR + K
Sbjct 390 LMRDAKIYQIYEGTSQIQRLIVAREHIDK 418
>Q3SZB4 Medium-chain specific acyl-CoA dehydrogenase, mitochondrial
[Bos taurus]
Length=421
Score = 184 bits (467), Expect = 3e-57
Identities = 119/315 (38%), Positives = 170/315 (54%), Gaps = 17/315 (5%)
Query 91 EMCYGDTGLLLSMPRQGLGNSAIAAVANDEQLERFKGTWA------AMAITEPGCGSDSA 144
E+ YG TG+ ++ LG + ND+Q +++ G A +TEP GSD A
Sbjct 111 ELAYGCTGVQTAIEANSLGQMPVIIAGNDQQQKKYLGRMTEEPLMCAYCVTEPVAGSDVA 170
Query 145 AIRTTAVKAGDEYILNGEKIYVTSGERADSVVVWATLD---RKLGRAAIKSFVVPKGTPG 201
I+T A K GDEYI+NG+K+++T+G +A+ + A D + A F+V TPG
Sbjct 171 GIKTKAEKKGDEYIINGQKMWITNGGKANWYFLLARSDPDPKAPASKAFTGFIVEADTPG 230
Query 202 MKVERLEHKLGIKASDTAAISFIDCRVPAANLLGNAEIDVAKGFAGVMETFDNTRPLVAA 261
+++ R E +G + SDT I F D RVP N+L I GF M FD TRP VAA
Sbjct 231 VQIGRKELNMGQRCSDTRGIVFEDVRVPKENVL----IGEGAGFKIAMGAFDKTRPPVAA 286
Query 262 MAVGCAKASL-ERIKEIFKDELDTDYATPYLQTSFIAAQIYRMEAEWEAARLLTLKATWM 320
AVG A+ +L E K + + + SF+ A+ M + E ARL +A W
Sbjct 287 AAVGLAQRALDEATKYALERKTFGKLLIEHQGISFLLAE---MAMKVELARLSYQRAAWE 343
Query 321 ADNKKPNSKEASIAKAKAGRICNEITLKCVELAASVGYNEDELLEKWARDSKILDIFEGT 380
D+ + N+ ASIAKA AG I N++ V++ G+N + +EK RD+KI I+EGT
Sbjct 344 VDSGRRNTYYASIAKAYAGDIANQLASDAVQIFGGNGFNTEYPVEKLMRDAKIYQIYEGT 403
Query 381 QQIQLLIIARRELGK 395
QIQ LIIAR +G+
Sbjct 404 AQIQRLIIAREHIGR 418
>P45952 Medium-chain specific acyl-CoA dehydrogenase, mitochondrial
[Mus musculus]
Length=421
Score = 183 bits (464), Expect = 8e-57
Identities = 115/314 (37%), Positives = 171/314 (54%), Gaps = 15/314 (5%)
Query 91 EMCYGDTGLLLSMPRQGLGNSAIAAVANDEQLERFKGTWA------AMAITEPGCGSDSA 144
E+ YG TG+ ++ LG + ND+Q +++ G A +TEP GSD A
Sbjct 111 ELAYGCTGVQTAIEANSLGQMPVILAGNDQQKKKYLGRMTEQPMMCAYCVTEPSAGSDVA 170
Query 145 AIRTTAVKAGDEYILNGEKIYVTSGERADSVVVWATL--DRKLGRA-AIKSFVVPKGTPG 201
AI+T A K GDEY++NG+K+++T+G +A+ + A D K+ + A F+V TPG
Sbjct 171 AIKTKAEKKGDEYVINGQKMWITNGGKANWYFLLARSNPDPKVPASKAFTGFIVEADTPG 230
Query 202 MKVERLEHKLGIKASDTAAISFIDCRVPAANLLGNAEIDVAKGFAGVMETFDNTRPLVAA 261
+ + + E +G + SDT I+F D RVP N+L I GF M FD TRP VAA
Sbjct 231 IHIGKKELNMGQRCSDTRGIAFEDVRVPKENVL----IGEGAGFKIAMGAFDRTRPTVAA 286
Query 262 MAVGCAKASLERIKEIFKDELDTDYATPYLQTSFIAAQIYRMEAEWEAARLLTLKATWMA 321
AVG A+ +L+ + D + ++ ++ + M + E ARL +A W
Sbjct 287 GAVGLAQRALDEATKYALDR--KTFGKLLVEHQGVSFLLAEMAMKVELARLSYQRAAWEV 344
Query 322 DNKKPNSKEASIAKAKAGRICNEITLKCVELAASVGYNEDELLEKWARDSKILDIFEGTQ 381
D+ + N+ ASIAKA AG I N++ V++ G+N + +EK RD+KI I+EGT
Sbjct 345 DSGRRNTYYASIAKAFAGDIANQLATDAVQIFGGYGFNTEYPVEKLMRDAKIYQIYEGTA 404
Query 382 QIQLLIIARRELGK 395
QIQ LIIAR + K
Sbjct 405 QIQRLIIAREHIEK 418
>P08503 Medium-chain specific acyl-CoA dehydrogenase, mitochondrial
[Rattus norvegicus]
Length=421
Score = 182 bits (462), Expect = 1e-56
Identities = 114/314 (36%), Positives = 171/314 (54%), Gaps = 15/314 (5%)
Query 91 EMCYGDTGLLLSMPRQGLGNSAIAAVANDEQLERFKGTWA------AMAITEPGCGSDSA 144
E+ YG TG+ ++ LG + ND+Q +++ G A +TEP GSD A
Sbjct 111 ELAYGCTGVQTAIEANSLGQMPVIIAGNDQQKKKYLGRMTEQPMMCAYCVTEPSAGSDVA 170
Query 145 AIRTTAVKAGDEYILNGEKIYVTSGERAD--SVVVWATLDRKLGRA-AIKSFVVPKGTPG 201
I+T A K GDEY++NG+K+++T+G +A+ V+ + D K+ + A F+V TPG
Sbjct 171 GIKTKAEKKGDEYVINGQKMWITNGGKANWYFVLTRSNPDPKVPASKAFTGFIVEADTPG 230
Query 202 MKVERLEHKLGIKASDTAAISFIDCRVPAANLLGNAEIDVAKGFAGVMETFDNTRPLVAA 261
+ + + E +G + SDT I+F D RVP N+L I GF M FD TRP VAA
Sbjct 231 IHIGKKELNMGQRCSDTRGITFEDVRVPKENVL----IGEGAGFKIAMGAFDRTRPTVAA 286
Query 262 MAVGCAKASLERIKEIFKDELDTDYATPYLQTSFIAAQIYRMEAEWEAARLLTLKATWMA 321
AVG A+ +L+ + D + ++ ++ + M + E ARL +A W
Sbjct 287 GAVGLAQRALDEATKYALDR--KTFGKLLVEHQGVSFLLAEMAMKVELARLSYQRAAWEV 344
Query 322 DNKKPNSKEASIAKAKAGRICNEITLKCVELAASVGYNEDELLEKWARDSKILDIFEGTQ 381
D+ + N+ ASIAKA AG I N++ V++ G+N + +EK RD+KI I+EGT
Sbjct 345 DSGRRNTYFASIAKAFAGDIANQLATDAVQIFGGYGFNTEYPVEKLMRDAKIYQIYEGTA 404
Query 382 QIQLLIIARRELGK 395
QIQ LIIAR + K
Sbjct 405 QIQRLIIAREHIEK 418
>Q8HXY8 Medium-chain specific acyl-CoA dehydrogenase, mitochondrial
[Macaca fascicularis]
Length=421
Score = 181 bits (459), Expect = 4e-56
Identities = 130/392 (33%), Positives = 191/392 (49%), Gaps = 31/392 (8%)
Query 16 AHDVALNVLRPISRKYDKAEHAYPKELDMLASLIDGMNEGGDGINAGATGAGKRGENEQQ 75
A A + P++ +YDK YP L A + MN N G G G
Sbjct 52 ARKFAREEIIPVAAEYDKTGE-YPVPLIRRAWELGLMNPHIPQ-NCGGLGLG-------- 101
Query 76 GIRNGTNMSTALGIIEMCYGDTGLLLSMPRQGLGNSAIAAVANDEQLERFKGTWA----- 130
L E+ YG TG+ ++ LG I N++Q +++ G
Sbjct 102 ------TFDACLISEELAYGCTGVQTAIEGNSLGQMPIIIAGNEQQKKKYLGRMTEEPLM 155
Query 131 -AMAITEPGCGSDSAAIRTTAVKAGDEYILNGEKIYVTSGERADSVVVWATLD---RKLG 186
A +TEPG GSD A I+T A K GDEYI+NG+K+++T+G +A + A D +
Sbjct 156 CAYCVTEPGAGSDVAGIKTKAEKKGDEYIINGQKMWITNGGKASWYFLLARSDPDPKAPA 215
Query 187 RAAIKSFVVPKGTPGMKVERLEHKLGIKASDTAAISFIDCRVPAANLLGNAEIDVAKGFA 246
A F+V TPG+++ R E +G + SDT I F D +V N+L I GF
Sbjct 216 NKAFTGFIVEADTPGIQIGRKELNMGQRCSDTRGIVFEDVKVLKENVL----IGDGAGFK 271
Query 247 GVMETFDNTRPLVAAMAVGCAKASLERIKEIFKDELDTDYATPYLQTSFIAAQIYRMEAE 306
M FD TRP V++ AVG A+ +L+ + + + ++ I+ + M +
Sbjct 272 IAMGAFDKTRPTVSSGAVGLAQRALDEATKYALER--KTFGKLLIEHQAISFMLAEMAMK 329
Query 307 WEAARLLTLKATWMADNKKPNSKEASIAKAKAGRICNEITLKCVELAASVGYNEDELLEK 366
E AR+ +A W D+ + N+ ASIAKA AG I N++ V++ G+N + +EK
Sbjct 330 VELARMSYQRAAWEVDSGRRNTYYASIAKAFAGDIANQLATDAVQIFGGNGFNTEYPVEK 389
Query 367 WARDSKILDIFEGTQQIQLLIIARRELGKSSS 398
RD+KI I+EGT QIQ LIIAR +GK S
Sbjct 390 LMRDAKIYQIYEGTSQIQRLIIAREHIGKYKS 421
>P41367 Medium-chain specific acyl-CoA dehydrogenase, mitochondrial
[Sus scrofa]
Length=421
Score = 178 bits (452), Expect = 4e-55
Identities = 121/326 (37%), Positives = 172/326 (53%), Gaps = 24/326 (7%)
Query 87 LGIIEMC-------YGDTGLLLSMPRQGLGNSAIAAVANDEQLERFKGTWA------AMA 133
LGII+ C YG TG+ ++ LG + N +Q +++ G A
Sbjct 100 LGIIDSCLITEELAYGCTGVQTAIEANTLGQVPLIIGGNYQQQKKYLGRMTEEPLMCAYC 159
Query 134 ITEPGCGSDSAAIRTTAVKAGDEYILNGEKIYVTSGERADSVVVWATLD---RKLGRAAI 190
+TEPG GSD A I+T A K GDEYI+NG+K+++T+G +A+ + A D + A
Sbjct 160 VTEPGAGSDVAGIKTKAEKKGDEYIINGQKMWITNGGKANWYFLLARSDPDPKAPASKAF 219
Query 191 KSFVVPKGTPGMKVERLEHKLGIKASDTAAISFIDCRVPAANLLGNAEIDVAKGFAGVME 250
F+V TPG+++ R E +G + SDT I F D RVP N+L GF M
Sbjct 220 TGFIVEADTPGVQIGRKEINMGQRCSDTRGIVFEDVRVPKENVLTGE----GAGFKIAMG 275
Query 251 TFDNTRPLVAAMAVGCAKASL-ERIKEIFKDELDTDYATPYLQTSFIAAQIYRMEAEWEA 309
TFD TRP VAA AVG A+ +L E K + + + SF+ A M + E
Sbjct 276 TFDKTRPPVAAGAVGLAQRALDEATKYALERKTFGKLLAEHQGISFLLAD---MAMKVEL 332
Query 310 ARLLTLKATWMADNKKPNSKEASIAKAKAGRICNEITLKCVELAASVGYNEDELLEKWAR 369
ARL +A W D+ + N+ ASIAKA A I N++ V++ G+N + +EK R
Sbjct 333 ARLSYQRAAWEIDSGRRNTYYASIAKAYAADIANQLATDAVQVFGGNGFNTEYPVEKLMR 392
Query 370 DSKILDIFEGTQQIQLLIIARRELGK 395
D+KI I+EGT QIQ +IIAR +G+
Sbjct 393 DAKIYQIYEGTAQIQRIIIAREHIGR 418
>P15651 Short-chain specific acyl-CoA dehydrogenase, mitochondrial
[Rattus norvegicus]
Length=412
Score = 177 bits (450), Expect = 7e-55
Identities = 127/393 (32%), Positives = 203/393 (52%), Gaps = 33/393 (8%)
Query 6 PKKFKMMVNQAHDVALNVLRPISRKYDKAEHAYPKELDMLASLIDGMNEGG---DGINAG 62
P+ +M+ D A L PI+ + DK EH +P S + M E G +
Sbjct 35 PETHQMLRQTCRDFAEKELVPIAAQLDK-EHLFP------TSQVKKMGELGLLAMDVPEE 87
Query 63 ATGAGKRGENEQQGIRNGTNMSTALGIIEMCYGDTGLLLSMPRQGLGNSAIAAVANDEQL 122
+GAG + S AL I TG+++S+ L I + +Q
Sbjct 88 LSGAGL----------DYLAYSIALEEISRGCASTGVIMSV-NNSLYLGPILKFGSSQQK 136
Query 123 ERFKGTWA------AMAITEPGCGSDSAAIRTTAVKAGDEYILNGEKIYVTSGERADSVV 176
+++ + A++EPG GSD+ A TTA + GD ++LNG K ++T+ A + V
Sbjct 137 QQWITPFTNGDKIGCFALSEPGNGSDAGAASTTAREEGDSWVLNGTKAWITNSWEASATV 196
Query 177 VWATLDRKLGRAAIKSFVVPKGTPGMKVERLEHKLGIKASDTAAISFIDCRVPAANLLGN 236
V+A+ DR I +F+VP TPG+ + + E KLGI+AS TA + F DCR+P NLLG
Sbjct 197 VFASTDRSRQNKGISAFLVPMPTPGLTLGKKEDKLGIRASSTANLIFEDCRIPKENLLG- 255
Query 237 AEIDVAKGFAGVMETFDNTRPLVAAMAVGCAKASLERIKEIFKDELDTDYATPYLQTSFI 296
+ GF M+T D R +A+ A+G A+ASL+ + ++ + P + I
Sbjct 256 ---EPGMGFKIAMQTLDMGRIGIASQALGIAQASLDCAVKYAENR--HAFGAPLTKLQNI 310
Query 297 AAQIYRMEAEWEAARLLTLKATWMADNKKPNSKEASIAKAKAGRICNEITLKCVELAASV 356
++ M E+ARLLT +A + DNKKP +KE+++AK A I+ + +++ +
Sbjct 311 QFKLADMALALESARLLTWRAAMLKDNKKPFTKESAMAKLAASEAATAISHQAIQILGGM 370
Query 357 GYNEDELLEKWARDSKILDIFEGTQQIQLLIIA 389
GY + E++ RD++I +I+EGT +IQ L+IA
Sbjct 371 GYVTEMPAERYYRDARITEIYEGTSEIQRLVIA 403
>Q07417 Short-chain specific acyl-CoA dehydrogenase, mitochondrial
[Mus musculus]
Length=412
Score = 177 bits (448), Expect = 1e-54
Identities = 126/394 (32%), Positives = 204/394 (52%), Gaps = 35/394 (9%)
Query 6 PKKFKMMVNQAHDVALNVLRPISRKYDKAEHAYP----KELDMLASLIDGMNEGGDGINA 61
P+ +M+ D A L PI+ + D+ EH +P K++ L L + E
Sbjct 35 PETHQMLRQTCRDFAEKELVPIAAQLDR-EHLFPTAQVKKMGELGLLAMDVPEE------ 87
Query 62 GATGAGKRGENEQQGIRNGTNMSTALGIIEMCYGDTGLLLSMPRQGLGNSAIAAVANDEQ 121
+GAG + S AL I TG+++S+ L I + +Q
Sbjct 88 -LSGAGL----------DYLAYSIALEEISRACASTGVIMSV-NNSLYLGPILKFGSAQQ 135
Query 122 LERFKGTWA------AMAITEPGCGSDSAAIRTTAVKAGDEYILNGEKIYVTSGERADSV 175
+++ + A++EPG GSD+ A TTA + GD ++LNG K ++T+ A +
Sbjct 136 KQQWITPFTNGDKIGCFALSEPGNGSDAGAASTTAREEGDSWVLNGTKAWITNSWEASAT 195
Query 176 VVWATLDRKLGRAAIKSFVVPKGTPGMKVERLEHKLGIKASDTAAISFIDCRVPAANLLG 235
VV+A+ DR I +F+VP TPG+ + + E KLGI+AS TA + F DCR+P NLLG
Sbjct 196 VVFASTDRSRQNKGISAFLVPMPTPGLTLGKKEDKLGIRASSTANLIFEDCRIPKENLLG 255
Query 236 NAEIDVAKGFAGVMETFDNTRPLVAAMAVGCAKASLERIKEIFKDELDTDYATPYLQTSF 295
+ GF M+T D R +A+ A+G A+ASL+ + ++ + P +
Sbjct 256 ----EPGMGFKIAMQTLDMGRIGIASQALGIAQASLDCAVKYAENR--NAFGAPLTKLQN 309
Query 296 IAAQIYRMEAEWEAARLLTLKATWMADNKKPNSKEASIAKAKAGRICNEITLKCVELAAS 355
I ++ M E+ARLLT +A + DNKKP +KE+++AK A I+ + +++
Sbjct 310 IQFKLADMALALESARLLTWRAAMLKDNKKPFTKESAMAKLAASEAATAISHQAIQILGG 369
Query 356 VGYNEDELLEKWARDSKILDIFEGTQQIQLLIIA 389
+GY + E++ RD++I +I+EGT +IQ L+IA
Sbjct 370 MGYVTEMPAERYYRDARITEIYEGTSEIQRLVIA 403
>Q9VSA3 Medium-chain specific acyl-CoA dehydrogenase, mitochondrial
[Drosophila melanogaster]
Length=419
Score = 177 bits (448), Expect = 2e-54
Identities = 118/317 (37%), Positives = 169/317 (53%), Gaps = 17/317 (5%)
Query 84 STALGIIEMCYGDTGLLLSMPRQGLGNSAIAAVANDEQLERFKGTW------AAMAITEP 137
+T L E+ YG TG++ ++ GLG + + N EQ +++ G AA +TEP
Sbjct 100 TTCLSAEELAYGCTGIMTALEASGLGQTPVILSGNKEQKKKYLGRLLEEPLVAAYCVTEP 159
Query 138 GCGSDSAAIRTTAVKAGDEYILNGEKIYVTSGERADSVVVWATL--DRKLGRA-AIKSFV 194
G GSD + I+T A K GDE+++NG+K+++T+G A+ V A D K + A F+
Sbjct 160 GAGSDVSGIKTRAEKKGDEWVINGQKMWITNGGVANWYFVLARTNPDPKCPPSKAFTGFI 219
Query 195 VPKGTPGMKVERLEHKLGIKASDTAAISFIDCRVPAANLLGNAEIDVAKGFAGVMETFDN 254
V + +PG+ R E +G +ASDT I+F D RVP N+L I GF M TFD
Sbjct 220 VERDSPGLTPGRKELNMGQRASDTRGITFEDVRVPKENVL----IGEGAGFKIAMGTFDK 275
Query 255 TRPLVAAMAVGCAKASLERIKEIFKDELDTD-YATPYLQTSFIAAQIYRMEAEWEAARLL 313
TRP VAA AVG A+ L+ E K L+ + P + + M E +RL
Sbjct 276 TRPPVAAGAVGLAQRCLD---EALKYALERKTFGVPIAYHQAVQFMLADMAIGVETSRLA 332
Query 314 TLKATWMADNKKPNSKEASIAKAKAGRICNEITLKCVELAASVGYNEDELLEKWARDSKI 373
+ W D + NS ASIAK A + N+I V++ G+N + +EK RD+KI
Sbjct 333 WRLSAWEIDQGRRNSYYASIAKCHAADMANKIASDAVQIFGGNGFNSEYPVEKLMRDAKI 392
Query 374 LDIFEGTQQIQLLIIAR 390
I+EGT QIQ LII+R
Sbjct 393 YQIYEGTSQIQRLIISR 409
>Q5RAS0 Short-chain specific acyl-CoA dehydrogenase, mitochondrial
[Pongo abelii]
Length=412
Score = 176 bits (447), Expect = 2e-54
Identities = 125/392 (32%), Positives = 206/392 (53%), Gaps = 31/392 (8%)
Query 6 PKKFKMMVNQAHDVALNVLRPISRKYDKAEHAYPKELDMLASLIDGMNEGGDGINAGATG 65
P+ +M++ D A L PI+ + DK EH +P A+ + M GG G+ A
Sbjct 35 PETHQMLLQTCRDFAEKELFPIAAQVDK-EHLFP------AAQVKKM--GGLGLLA---- 81
Query 66 AGKRGENEQQGIRNGTNMSTALGIIEMCYG--DTGLLLSMPRQGLGNSAIAAVANDEQLE 123
E+ G ++ A+ + E+ G TG+++S+ L I + EQ +
Sbjct 82 ---MDVPEELGGAGLDYLAYAIAMEEISRGCASTGVIMSV-NNSLYLGPILKFGSKEQKQ 137
Query 124 RFKGTWAA------MAITEPGCGSDSAAIRTTAVKAGDEYILNGEKIYVTSGERADSVVV 177
++ + + A++EPG GSD+ A TTA GD ++LNG K ++T+ A + VV
Sbjct 138 KWVTPFTSGDKIGCFALSEPGNGSDAGAASTTARAEGDSWVLNGTKAWITNAWEASAAVV 197
Query 178 WATLDRKLGRAAIKSFVVPKGTPGMKVERLEHKLGIKASDTAAISFIDCRVPAANLLGNA 237
+A+ DR L I +F+VP TPG+ + + E KLGI+ S TA + F DCR+P ++LG
Sbjct 198 FASTDRALQNKGISAFLVPMPTPGLTLGKKEDKLGIRGSSTANLIFEDCRIPKDSILG-- 255
Query 238 EIDVAKGFAGVMETFDNTRPLVAAMAVGCAKASLERIKEIFKDELDTDYATPYLQTSFIA 297
+ GF M+T D R +A+ A+G A+ +L+ ++ + + P + I
Sbjct 256 --EPGMGFKIAMQTLDMGRIGIASQALGIAQTALDCAVNYAENRM--AFGAPLTKLQVIQ 311
Query 298 AQIYRMEAEWEAARLLTLKATWMADNKKPNSKEASIAKAKAGRICNEITLKCVELAASVG 357
++ M E+ARLLT +A + DNKKP KEA++AK A I+ + +++ +G
Sbjct 312 FKLADMALALESARLLTWRAAMLKDNKKPFIKEAAMAKLAASEAATAISHQAIQILGGMG 371
Query 358 YNEDELLEKWARDSKILDIFEGTQQIQLLIIA 389
Y + E+ RD++I +I+EGT +IQ L+IA
Sbjct 372 YVTEMPAERHYRDARITEIYEGTSEIQRLVIA 403
>O34421 Probable acyl-CoA dehydrogenase YngJ [Bacillus subtilis
(strain 168)]
Length=380
Score = 174 bits (442), Expect = 5e-54
Identities = 114/330 (35%), Positives = 177/330 (54%), Gaps = 16/330 (5%)
Query 73 EQQGIRNGTNMSTALGIIEM--CYGDTGLLLSMPRQGLGNSAIAAVANDEQLERF----- 125
E+ G G +S AL + E+ G TGL + LG S + +EQ +
Sbjct 57 EEYGGSGGDTISYALAVEEVGKACGSTGLSYAAA-VSLGASPLYYFGTEEQKQTHLTPLA 115
Query 126 KGT-WAAMAITEPGCGSDSAAIRTTAVKAGDEYILNGEKIYVTSGERADSVVVWATLDR- 183
GT + +TEP GSD+ +T A+ GDEY++NGEK ++T+ A +V+V A +
Sbjct 116 SGTALGSFGLTEPNAGSDAGGTQTKAISNGDEYVINGEKCWITNASYARTVIVTAVTGKN 175
Query 184 KLGRAAIKSFVVPKGTPGMKVERLEHKLGIKASDTAAISFIDCRVPAANLLGNAEIDVAK 243
K G+ I + +VP TPG+ + K+G++ S+TA I D RVPAANLLG D K
Sbjct 176 KDGKNIISALIVPTDTPGLTITSPYDKMGVRGSNTAEILLEDVRVPAANLLG----DPTK 231
Query 244 GFAGVMETFDNTRPLVAAMAVGCAKASLERIKEIFKDELDTDYATPYLQTSFIAAQIYRM 303
GF + T D R +AA+AVG A+A+L+ K+ + P I ++ M
Sbjct 232 GFKQFLYTLDGGRISIAALAVGIAQAALDASLAYAKER--KQFGQPISSFQAIQFKLADM 289
Query 304 EAEWEAARLLTLKATWMADNKKPNSKEASIAKAKAGRICNEITLKCVELAASVGYNEDEL 363
E + AR + LKA W+ D+ +P +KEA+ AK A + + +++ GY ++
Sbjct 290 AMEIDLARQMVLKAAWLKDHNRPFTKEAAYAKLFASEMATRACNQAIQIHGGSGYMKEYG 349
Query 364 LEKWARDSKILDIFEGTQQIQLLIIARREL 393
+E+ RD+K+++I EGT +IQ L+IAR+ L
Sbjct 350 VERMLRDAKLMEIGEGTSEIQRLVIARQLL 379
>P16219 Short-chain specific acyl-CoA dehydrogenase, mitochondrial
[Homo sapiens]
Length=412
Score = 175 bits (444), Expect = 5e-54
Identities = 125/392 (32%), Positives = 205/392 (52%), Gaps = 31/392 (8%)
Query 6 PKKFKMMVNQAHDVALNVLRPISRKYDKAEHAYPKELDMLASLIDGMNEGGDGINAGATG 65
P+ +M++ D A L PI+ + DK EH +P A+ + M GG G+ A
Sbjct 35 PETHQMLLQTCRDFAEKELFPIAAQVDK-EHLFP------AAQVKKM--GGLGLLA---- 81
Query 66 AGKRGENEQQGIRNGTNMSTALGIIEMCYG--DTGLLLSMPRQGLGNSAIAAVANDEQLE 123
E+ G ++ A+ + E+ G TG+++S+ L I + EQ +
Sbjct 82 ---MDVPEELGGAGLDYLAYAIAMEEISRGCASTGVIMSV-NNSLYLGPILKFGSKEQKQ 137
Query 124 RFKGTWAA------MAITEPGCGSDSAAIRTTAVKAGDEYILNGEKIYVTSGERADSVVV 177
+ + + A++EPG GSD+ A TTA GD ++LNG K ++T+ A + VV
Sbjct 138 AWVTPFTSGDKIGCFALSEPGNGSDAGAASTTARAEGDSWVLNGTKAWITNAWEASAAVV 197
Query 178 WATLDRKLGRAAIKSFVVPKGTPGMKVERLEHKLGIKASDTAAISFIDCRVPAANLLGNA 237
+A+ DR L I +F+VP TPG+ + + E KLGI+ S TA + F DCR+P ++LG
Sbjct 198 FASTDRALQNKGISAFLVPMPTPGLTLGKKEDKLGIRGSSTANLIFEDCRIPKDSILG-- 255
Query 238 EIDVAKGFAGVMETFDNTRPLVAAMAVGCAKASLERIKEIFKDELDTDYATPYLQTSFIA 297
+ GF M+T D R +A+ A+G A+ +L+ ++ + + P + I
Sbjct 256 --EPGMGFKIAMQTLDMGRIGIASQALGIAQTALDCAVNYAENRM--AFGAPLTKLQVIQ 311
Query 298 AQIYRMEAEWEAARLLTLKATWMADNKKPNSKEASIAKAKAGRICNEITLKCVELAASVG 357
++ M E+ARLLT +A + DNKKP KEA++AK A I+ + +++ +G
Sbjct 312 FKLADMALALESARLLTWRAAMLKDNKKPFIKEAAMAKLAASEAATAISHQAIQILGGMG 371
Query 358 YNEDELLEKWARDSKILDIFEGTQQIQLLIIA 389
Y + E+ RD++I +I+EGT +IQ L+IA
Sbjct 372 YVTEMPAERHYRDARITEIYEGTSEIQRLVIA 403
>Q3ZBF6 Short-chain specific acyl-CoA dehydrogenase, mitochondrial
[Bos taurus]
Length=412
Score = 175 bits (443), Expect = 7e-54
Identities = 127/393 (32%), Positives = 204/393 (52%), Gaps = 33/393 (8%)
Query 6 PKKFKMMVNQAHDVALNVLRPISRKYDKAEHAYPKELDMLASLIDGMNEGG---DGINAG 62
P+ +M+ D A L PI+ + DK EH +P A+ + M E G +
Sbjct 35 PETHQMLRQTCRDFAEKELFPIAAQVDK-EHRFP------AAQVKKMGELGLMAMNVPEE 87
Query 63 ATGAGKRGENEQQGIRNGTNMSTALGIIEMCYGDTGLLLSMPRQGLGNSAIAAVANDEQL 122
+GAG + S A+ I TG+++S+ L I EQ
Sbjct 88 LSGAGL----------DYLAYSIAMEEISRGCASTGVIMSV-NNSLYLGPILKFGTKEQK 136
Query 123 ERFKGTWAA------MAITEPGCGSDSAAIRTTAVKAGDEYILNGEKIYVTSGERADSVV 176
+++ + + A++EPG GSD+ A TTA GD ++L+G K ++T+ A +VV
Sbjct 137 QQWVAPFTSGDKIGCFALSEPGNGSDAGAAATTARADGDSWVLSGTKAWITNAWEASAVV 196
Query 177 VWATLDRKLGRAAIKSFVVPKGTPGMKVERLEHKLGIKASDTAAISFIDCRVPAANLLGN 236
V+A+ DR L I +F+VP TPG+ + + E KLGI+AS TA + F D R+P +LLG
Sbjct 197 VFASTDRSLHNKGISAFLVPMPTPGLTLGKKEDKLGIRASSTANLIFEDRRIPKDSLLGE 256
Query 237 AEIDVAKGFAGVMETFDNTRPLVAAMAVGCAKASLERIKEIFKDELDTDYATPYLQTSFI 296
+ GF M+T D R +A+ A+G A+A+L+ + E + + P + I
Sbjct 257 PGL----GFKIAMQTLDTGRIGIASQALGIAQAALD--CAVTYAENRSAFGAPLTKLQAI 310
Query 297 AAQIYRMEAEWEAARLLTLKATWMADNKKPNSKEASIAKAKAGRICNEITLKCVELAASV 356
++ M E+ARLLT +A + DNKKP +KEA++AK A IT + +++ +
Sbjct 311 QFKLADMALALESARLLTWRAAMLKDNKKPFTKEAAMAKLAASEAATAITHQAMQILGGM 370
Query 357 GYNEDELLEKWARDSKILDIFEGTQQIQLLIIA 389
GY ++ E+ RD++I +I+EGT +IQ L++A
Sbjct 371 GYVKEMPAERHYRDARITEIYEGTSEIQRLVVA 403
>P45867 Acyl-CoA dehydrogenase [Bacillus subtilis (strain 168)]
Length=379
Score = 172 bits (437), Expect = 2e-53
Identities = 95/260 (37%), Positives = 153/260 (59%), Gaps = 6/260 (2%)
Query 131 AMAITEPGCGSDSAAIRTTAVKAGDEYILNGEKIYVTSGERADSVVVWATLDRKLGRAAI 190
A A+TE G GSD+ +++TTA + GD+Y+LNG K+++T+G AD +V+A D + + +
Sbjct 122 AFALTEAGSGSDAGSMKTTAERIGDDYVLNGSKVFITNGGVADIYIVFAVTDPEKKKKGV 181
Query 191 KSFVVPKGTPGMKVERLEHKLGIKASDTAAISFIDCRVPAANLLGNAEIDVAKGFAGVME 250
+F+V K G + E KLGI++S T I F DC VPA+ LG + +GF M+
Sbjct 182 TAFIVEKDFEGFFTGKKEKKLGIRSSPTTEIMFEDCVVPASKRLG----EEGEGFKIAMK 237
Query 251 TFDNTRPLVAAMAVGCAKASLERIKEIFKDELDTDYATPYLQTSFIAAQIYRMEAEWEAA 310
T D R +AA AVG A+ +L+ + K+ + + IA ++ M EA+
Sbjct 238 TLDGGRNGIAAQAVGIAQGALDAALQYAKER--KQFGKSIAEQQGIAFKLADMATMIEAS 295
Query 311 RLLTLKATWMADNKKPNSKEASIAKAKAGRICNEITLKCVELAASVGYNEDELLEKWARD 370
RLLT +A W+ + P K ++++K AG ++T + V++ GY +D +E++ RD
Sbjct 296 RLLTYQAAWLESSGLPYGKASAMSKLMAGDTAMKVTTEAVQIFGGYGYTKDYPVERYMRD 355
Query 371 SKILDIFEGTQQIQLLIIAR 390
+KI I+EGTQ+IQ L+I+R
Sbjct 356 AKITQIYEGTQEIQRLVISR 375
Lambda K H a alpha
0.317 0.132 0.378 0.792 4.96
Gapped
Lambda K H a alpha sigma
0.267 0.0410 0.140 1.90 42.6 43.6
Effective search space used: 1913120
Database: f2078f6338c6c800f90f1847edbe29af.SwissProt.fasta
Posted date: May 18, 2024 3:56 PM
Number of letters in database: 6,185
Number of sequences in database: 15
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Neighboring words threshold: 11
Window for multiple hits: 40
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Data ...
