BLASTP 2.12.0+
Reference: Stephen F. Altschul, Thomas L. Madden, Alejandro A.
Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J.
Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of
protein database search programs", Nucleic Acids Res. 25:3389-3402.
Reference for composition-based statistics: Alejandro A. Schaffer,
L. Aravind, Thomas L. Madden, Sergei Shavirin, John L. Spouge, Yuri
I. Wolf, Eugene V. Koonin, and Stephen F. Altschul (2001),
"Improving the accuracy of PSI-BLAST protein database searches with
composition-based statistics and other refinements", Nucleic Acids
Res. 29:2994-3005.
Database: 900cda00dee352d27d0798827ebe7115.SwissProt.fasta
13 sequences; 4,802 total letters
Query= ACIAD1429
Length=372
Score E
Sequences producing significant alignments: (Bits) Value
P39849 Aryl-alcohol dehydrogenase [Pseudomonas putida] 418 1e-149
H1ZV38 Geraniol dehydrogenase [Castellaniella defragrans (strain ... 307 4e-106
P33010 Probable alcohol dehydrogenase [Pseudomonas sp] 243 7e-82
A4YGN0 Succinate-semialdehyde dehydrogenase (acetylating) [Metall... 212 3e-69
P07327 Alcohol dehydrogenase 1A [Homo sapiens] 201 1e-64
P00325 All-trans-retinol dehydrogenase [NAD(+)] ADH1B [Homo sapiens] 200 2e-64
Q5R1W2 All-trans-retinol dehydrogenase [NAD(+)] ADH1B [Pan troglo... 199 8e-64
Q5RBP7 Alcohol dehydrogenase 1A [Pongo abelii] 197 2e-63
Q17335 Alcohol dehydrogenase class-3 [Caenorhabditis elegans] 195 3e-62
P86883 Alcohol dehydrogenase 1 [Columba livia] 194 3e-62
P80512 Alcohol dehydrogenase 1 [Naja naja] 194 5e-62
P25405 Alcohol dehydrogenase 1A [Saara hardwickii] 192 2e-61
P14139 All-trans-retinol dehydrogenase [NAD(+)] ADH1B [Papio hama... 192 3e-61
>P39849 Aryl-alcohol dehydrogenase [Pseudomonas putida]
Length=366
Score = 418 bits (1074), Expect = 1e-149
Identities = 207/366 (57%), Positives = 259/366 (71%), Gaps = 1/366 (0%)
Query 6 EITAAVTECKGADFELKQLKIREPQNDEVLVKIVATGMCHTDLIVRDQYYPVPLPAVLGH 65
EI AA+ K F L+ + + EP D+VLV++VATG+CHTDL+ RDQ+YPVPLP V GH
Sbjct 2 EIKAAIVRQKNGPFLLEHVALNEPAEDQVLVRLVATGLCHTDLVCRDQHYPVPLPMVFGH 61
Query 66 EGSGIIEAIGPNVKDLAVGDHVVLSYGFCGSCEQCSSGQPAYCQDFFGRNFSGGDPDGHS 125
EG+G++E +G VK + GDHVVL++ CGSC+ C SG P C + FG NF G G
Sbjct 62 EGAGVVERVGSAVKKVQPGDHVVLTFYTCGSCDACLSGDPTSCANSFGPNFMGRSVTGEC 121
Query 126 AVCSHDHHKIHDHFFAQSSFATYAISRENNAVKVSKDVPLELLGPLGCGIQTGAGAAINA 185
+ H ++ FF QSSFATYA+S E N VKV+KDVPLELLGPLGCGIQTGAG+ +NA
Sbjct 122 TIHDHQGAEVGASFFGQSSFATYALSYERNTVKVTKDVPLELLGPLGCGIQTGAGSVLNA 181
Query 186 LKVAPASSFVTWGAGAVGLSALLAAKVCGATTIIAVDIVESRLALAKELGATHVINSKTQ 245
L S+ +GAGAVGLSA++AA V G TTIIAVD+ E+RL LA ELGATH+IN
Sbjct 182 LNPPAGSAIAIFGAGAVGLSAVMAAVVAGCTTIIAVDVKENRLELASELGATHIINPAAN 241
Query 246 DPVEAIKEITGGGVKFALESTGRPEILKQGIDALGILGSIAVVGAPPLGTTAAFDVNDLL 305
DP+EAIKEI GV + LE++G P +L Q I + I G I +VGAPP+G T D+N LL
Sbjct 242 DPIEAIKEIFADGVPYVLETSGLPAVLTQAILSSAIGGEIGIVGAPPMGATVPVDINFLL 301
Query 306 LGGKSIIGVVEGSGVPKKFIPALVSLYQQGKFPFDKLVKFYDFKDINQAAIDSHKGITLK 365
K + G+VEG + FIP LV LY+QGKFPFDKL+KFY F +IN+AA DS KG+TLK
Sbjct 302 FNRK-LRGIVEGQSISDIFIPRLVELYRQGKFPFDKLIKFYPFDEINRAAEDSEKGVTLK 360
Query 366 PILKIG 371
P+L+IG
Sbjct 361 PVLRIG 366
>H1ZV38 Geraniol dehydrogenase [Castellaniella defragrans (strain
DSM 12143 / CCUG 39792 / 65Phen)]
Length=373
Score = 307 bits (787), Expect = 4e-106
Identities = 161/366 (44%), Positives = 218/366 (60%), Gaps = 2/366 (1%)
Query 4 FTEITAAVTECKGADFELKQLKIREPQNDEVLVKIVATGMCHTDLIVRDQYYPVPLPAVL 63
F AAV G ++ ++I P+ DEVL++I G+CHTDL+ RD + PVPLP VL
Sbjct 7 FISAQAAVLRQVGGPLAVEPVRISMPKGDEVLIRIAGVGVCHTDLVCRDGF-PVPLPIVL 65
Query 64 GHEGSGIIEAIGPNVKDLAVGDHVVLSYGFCGSCEQCSSGQPAYCQDFFGRNFSGGDPDG 123
GHEGSG +EA+G V+ L GD VVLS+ CG C C G P+ C NF G
Sbjct 66 GHEGSGTVEAVGEQVRTLKPGDRVVLSFNSCGHCGNCHDGHPSNCLQMLPLNFGGAQRVD 125
Query 124 HSAVCSHDHHKIHDHFFAQSSFATYAISRENNAVKVSKDVPLELLGPLGCGIQTGAGAAI 183
V H + FF QSSF T+A++RE NAVKV D+PLELLGPLGCGIQTGAGAAI
Sbjct 126 GGQVLDGAGHPVQSMFFGQSSFGTHAVAREINAVKVGDDLPLELLGPLGCGIQTGAGAAI 185
Query 184 NALKVAPASSFVTWGAGAVGLSALLAAKVCGATTIIAVDIVESRLALAKELGATHVINSK 243
N+L + P S +G G VGLSALL A+ GA ++ ++ +R ALA ELGA+H ++
Sbjct 186 NSLGIGPGQSLAIFGGGGVGLSALLGARAVGADRVVVIEPNAARRALALELGASHALDPH 245
Query 244 TQ-DPVEAIKEITGGGVKFALESTGRPEILKQGIDALGILGSIAVVGAPPLGTTAAFDVN 302
+ D V AIK TGGG +L++TG P ++ I G++ +VG P +
Sbjct 246 AEGDLVAAIKAATGGGATHSLDTTGLPPVIGSAIACTLPGGTVGMVGLPAPDAPVPATLL 305
Query 303 DLLLGGKSIIGVVEGSGVPKKFIPALVSLYQQGKFPFDKLVKFYDFKDINQAAIDSHKGI 362
DLL ++ + EG P++FIP ++ ++ GKFPFD+L+ Y F IN+A + KG
Sbjct 306 DLLSKSVTLRPITEGDADPQRFIPRMLDFHRAGKFPFDRLITRYRFDQINEALHATEKGE 365
Query 363 TLKPIL 368
+KP+L
Sbjct 366 AIKPVL 371
>P33010 Probable alcohol dehydrogenase [Pseudomonas sp]
Length=319
Score = 243 bits (621), Expect = 7e-82
Identities = 131/280 (47%), Positives = 180/280 (64%), Gaps = 6/280 (2%)
Query 43 MCHTDLIVRDQYYPVPLPAVLGHEGSGIIEAIGPNVKDLAVGDHVVLSYGFCGSCEQCSS 102
+CHTDL ++D P PLPAVLGHEGSGI+EA+GP VK L GD VV+++ CG C C
Sbjct 17 VCHTDLAIKDGVLPFPLPAVLGHEGSGIVEAVGPGVKHLKPGDAVVMTFASCGHCASCEH 76
Query 103 GQPAYCQDFFGRNFSGGDPDGHSAVCSHDHHKIHDHFFAQSSFATYAISRENNAVKVS-- 160
+P+YC DF +N+S DG + S I FF QSSF++ A++RE+N VK+
Sbjct 77 ERPSYCLDFGAQNYSAQRADG-PVLLSQGDEVISGFFFGQSSFSSMAMAREHNLVKIDAL 135
Query 161 -KDVPLELLGPLGCGIQTGAGAAINALKVAPASSFVTWGAGAVGLSALLAAKVCGATTII 219
D P+ELLGPLGCG+QTGAGA + +L V SF+ G GAVGLSA++AAK+ G + II
Sbjct 136 VDDAPIELLGPLGCGVQTGAGAVMISLDVRAGRSFLVLGGGAVGLSAVMAAKLRGCSRII 195
Query 220 AVDIVESRLALAKELGATHVINSKTQDPVEAIKEIT-GGGVKFALESTGRPEILKQGIDA 278
+ ++ A LGAT VI+ ++ VE +++IT G G +ALE TG +++Q ID+
Sbjct 196 VSEPSAAKREQALALGATEVIDPLNENLVERVQQITEGQGCDYALECTGLVSVMEQAIDS 255
Query 279 LGILGSIAVVGAPP-LGTTAAFDVNDLLLGGKSIIGVVEG 317
+ + G +AVVG PP L TAA L+ G ++GV+EG
Sbjct 256 MAMRGQLAVVGVPPKLDATAAVSPLALIQKGLKLMGVIEG 295
>A4YGN0 Succinate-semialdehyde dehydrogenase (acetylating) [Metallosphaera
sedula (strain ATCC 51363 / DSM 5348 / JCM 9185
/ NBRC 15509 / TH2)]
Length=360
Score = 212 bits (540), Expect = 3e-69
Identities = 131/362 (36%), Positives = 197/362 (54%), Gaps = 8/362 (2%)
Query 9 AAVTECKGADFELKQLKIREPQNDEVLVKIVATGMCHTDLIVRDQYYPVPLPAVLGHEGS 68
AAV ++ + I +P+ EV +K+ ATG+CH+D+ V + PVP P V GHE S
Sbjct 3 AAVLHTYKEPLSIEDVNISQPKAGEVKIKVKATGLCHSDVNVFEGKTPVPPPVVAGHEIS 62
Query 69 GIIEAIGPNVKDLAVGDHVVLSYGF-CGSCEQCSSGQPAYCQDFFGRNFSGGDPDGHSAV 127
GI+E +GP V + GD V+ ++ CG C C +G+ C+ F G PDG S +
Sbjct 63 GIVEEVGPGVTRVKPGDRVISAFIHPCGKCGNCVAGKENLCETFSQVRLKGVMPDGTSRL 122
Query 128 CSHDHHKIHDHFFAQSSFATYAISRENNAVKVSKDVPLELLGPLGCGIQTGAGAAINALK 187
S D +I F FA YAI EN +V +D+ LE + LGC TG GA I++ K
Sbjct 123 -SKDGKEIRT--FLGGGFAEYAIVGENALTRVPEDMDLEKVAVLGCAGLTGYGA-ISSSK 178
Query 188 VAPASSFVTWGAGAVGLSALLAAKVCGATTIIAVDIVESRLALAKELGATHVINSKTQDP 247
+ P + G G VGLS + + GA IIAV + +L A ELGAT V+NSK DP
Sbjct 179 IEPGDTVAVIGVGGVGLSTIQLLRASGAGRIIAVGTKKWKLDRAMELGATDVVNSKEIDP 238
Query 248 VEAIKEITGGGVKFALESTGRPEILKQGIDALGILGSIAVVGAPPLGTTAAFDVNDLLLG 307
V+AIKEITGGG + +E+ G + + +D++ I G + +VG PP V ++ G
Sbjct 239 VKAIKEITGGGPQVVIEAGGNEDTIHMALDSVRIGGKVVLVGLPPATAMIPIRVASIVRG 298
Query 308 GKSIIGVVEGSGVPKKFIPALVSLYQQGKFPFDKLVK-FYDFKDINQAAIDSHKGITLKP 366
G ++G G P+ +P L+ L +QG++ +LV + ++IN+A +G ++
Sbjct 299 GIEVVG--NYGGRPRVDMPKLLELVRQGRYDPSRLVTGRFRLEEINEAVKMLEEGEAIRS 356
Query 367 IL 368
++
Sbjct 357 LI 358
>P07327 Alcohol dehydrogenase 1A [Homo sapiens]
Length=375
Score = 201 bits (510), Expect = 1e-64
Identities = 132/370 (36%), Positives = 193/370 (52%), Gaps = 15/370 (4%)
Query 11 VTECKGA-------DFELKQLKIREPQNDEVLVKIVATGMCHTDLIVRDQYYPVPLPAVL 63
V +CK A F ++++++ P+ EV +K+VA G+C TD V PLP +L
Sbjct 7 VIKCKAAVLWELKKPFSIEEVEVAPPKAHEVRIKMVAVGICGTDDHVVSGTMVTPLPVIL 66
Query 64 GHEGSGIIEAIGPNVKDLAVGDHVV-LSYGFCGSCEQCSSGQPAYCQDFFGRNFSGGDPD 122
GHE +GI+E++G V + GD V+ L+ CG C C + + YC N G D
Sbjct 67 GHEAAGIVESVGEGVTTVKPGDKVIPLAIPQCGKCRICKNPESNYCLKNDVSNPQGTLQD 126
Query 123 GHSAVCSHDHHKIHDHFFAQSSFATYAISRENNAVKVSKDVPLELLGPLGCGIQTGAGAA 182
G S IH HF S+F+ Y + EN K+ PLE + +GCG TG G+A
Sbjct 127 GTSRFTCR-RKPIH-HFLGISTFSQYTVVDENAVAKIDAASPLEKVCLIGCGFSTGYGSA 184
Query 183 INALKVAPASSFVTWGAGAVGLSALLAAKVCGATTIIAVDIVESRLALAKELGATHVINS 242
+N KV P S+ +G G VGLSA++ K GA IIAVDI + + A AKELGAT IN
Sbjct 185 VNVAKVTPGSTCAVFGLGGVGLSAIMGCKAAGAARIIAVDINKDKFAKAKELGATECINP 244
Query 243 KT-QDPV-EAIKEITGGGVKFALESTGRPEILKQGIDAL-GILGSIAVVGAPPLGTTAAF 299
+ + P+ E +KE+T GGV F+ E GR + + + G+ +VG PP +
Sbjct 245 QDYKKPIQEVLKEMTDGGVDFSFEVIGRLDTMMASLLCCHEACGTSVIVGVPPDSQNLSM 304
Query 300 DVNDLLLGGKSIIGVVEGSGVPKKFIPALVSLYQQGKFPFDKLV-KFYDFKDINQAAIDS 358
+ LLL G++ G + G K+ +P LV+ + KF D L+ F+ IN+
Sbjct 305 NPM-LLLTGRTWKGAILGGFKSKECVPKLVADFMAKKFSLDALITHVLPFEKINEGFDLL 363
Query 359 HKGITLKPIL 368
H G +++ IL
Sbjct 364 HSGKSIRTIL 373
>P00325 All-trans-retinol dehydrogenase [NAD(+)] ADH1B [Homo sapiens]
Length=375
Score = 200 bits (509), Expect = 2e-64
Identities = 133/370 (36%), Positives = 191/370 (52%), Gaps = 15/370 (4%)
Query 11 VTECKGA-------DFELKQLKIREPQNDEVLVKIVATGMCHTDLIVRDQYYPVPLPAVL 63
V +CK A F ++ +++ P+ EV +K+VA G+CHTD V PLP +L
Sbjct 7 VIKCKAAVLWEVKKPFSIEDVEVAPPKAYEVRIKMVAVGICHTDDHVVSGNLVTPLPVIL 66
Query 64 GHEGSGIIEAIGPNVKDLAVGDHVV-LSYGFCGSCEQCSSGQPAYCQDFFGRNFSGGDPD 122
GHE +GI+E++G V + GD V+ L CG C C + + YC N G D
Sbjct 67 GHEAAGIVESVGEGVTTVKPGDKVIPLFTPQCGKCRVCKNPESNYCLKNDLGNPRGTLQD 126
Query 123 GHSAVCSHDHHKIHDHFFAQSSFATYAISRENNAVKVSKDVPLELLGPLGCGIQTGAGAA 182
G IH HF S+F+ Y + EN K+ PLE + +GCG TG G+A
Sbjct 127 GTRRFTCRGK-PIH-HFLGTSTFSQYTVVDENAVAKIDAASPLEKVCLIGCGFSTGYGSA 184
Query 183 INALKVAPASSFVTWGAGAVGLSALLAAKVCGATTIIAVDIVESRLALAKELGATHVINS 242
+N KV P S+ +G G VGLSA++ K GA IIAVDI + + A AKELGAT IN
Sbjct 185 VNVAKVTPGSTCAVFGLGGVGLSAVMGCKAAGAARIIAVDINKDKFAKAKELGATECINP 244
Query 243 KT-QDPV-EAIKEITGGGVKFALESTGRPEILKQGIDAL-GILGSIAVVGAPPLGTTAAF 299
+ + P+ E +KE+T GGV F+ E GR + + + G+ +VG PP +
Sbjct 245 QDYKKPIQEVLKEMTDGGVDFSFEVIGRLDTMMASLLCCHEACGTSVIVGVPPASQNLSI 304
Query 300 DVNDLLLGGKSIIGVVEGSGVPKKFIPALVSLYQQGKFPFDKLV-KFYDFKDINQAAIDS 358
+ LLL G++ G V G K+ IP LV+ + KF D L+ F+ IN+
Sbjct 305 NPM-LLLTGRTWKGAVYGGFKSKEGIPKLVADFMAKKFSLDALITHVLPFEKINEGFDLL 363
Query 359 HKGITLKPIL 368
H G +++ +L
Sbjct 364 HSGKSIRTVL 373
>Q5R1W2 All-trans-retinol dehydrogenase [NAD(+)] ADH1B [Pan troglodytes]
Length=375
Score = 199 bits (505), Expect = 8e-64
Identities = 133/370 (36%), Positives = 191/370 (52%), Gaps = 15/370 (4%)
Query 11 VTECKGA-------DFELKQLKIREPQNDEVLVKIVATGMCHTDLIVRDQYYPVPLPAVL 63
V +CK A F ++ +++ P+ EV +K+VA G+C TD V PLPA+L
Sbjct 7 VIKCKAAVLWEVKKPFSIEDVEVAPPKAYEVRIKMVAVGICRTDDHVVSGNLVTPLPAIL 66
Query 64 GHEGSGIIEAIGPNVKDLAVGDHVV-LSYGFCGSCEQCSSGQPAYCQDFFGRNFSGGDPD 122
GHE +GI+E++G V + GD V+ L CG C C + + YC N G D
Sbjct 67 GHEAAGIVESVGEGVTTVKPGDKVIPLFTPQCGKCRVCKNPESNYCLKNDLGNPRGTLQD 126
Query 123 GHSAVCSHDHHKIHDHFFAQSSFATYAISRENNAVKVSKDVPLELLGPLGCGIQTGAGAA 182
G IH HF S+F+ Y + EN K+ PLE + +GCG TG G+A
Sbjct 127 GTRRFTCRGK-PIH-HFLGTSTFSQYTVVDENAVAKIDAASPLEKVCLIGCGFSTGYGSA 184
Query 183 INALKVAPASSFVTWGAGAVGLSALLAAKVCGATTIIAVDIVESRLALAKELGATHVINS 242
+N KV P S+ +G G VGLSA++ K GA IIAVDI + + A AKELGAT IN
Sbjct 185 VNVAKVTPGSTCAVFGLGGVGLSAVMGCKAAGAARIIAVDINKDKFAKAKELGATECINP 244
Query 243 KT-QDPV-EAIKEITGGGVKFALESTGRPEILKQGIDAL-GILGSIAVVGAPPLGTTAAF 299
+ + P+ E +KE+T GGV F+ E GR + + + G+ +VG PP +
Sbjct 245 QDYKKPIQEVLKEMTDGGVDFSFEVIGRLDTMMASLLCCHEACGTSVIVGVPPASQNLSI 304
Query 300 DVNDLLLGGKSIIGVVEGSGVPKKFIPALVSLYQQGKFPFDKLV-KFYDFKDINQAAIDS 358
+ LLL G++ G V G K+ IP LV+ + KF D L+ F+ IN+
Sbjct 305 NPM-LLLTGRTWKGAVYGGFKSKEGIPKLVADFMAKKFSLDALITHVLPFEKINEGFDLL 363
Query 359 HKGITLKPIL 368
H G +++ +L
Sbjct 364 HSGKSIRTVL 373
>Q5RBP7 Alcohol dehydrogenase 1A [Pongo abelii]
Length=375
Score = 197 bits (502), Expect = 2e-63
Identities = 132/370 (36%), Positives = 191/370 (52%), Gaps = 15/370 (4%)
Query 11 VTECKGA-------DFELKQLKIREPQNDEVLVKIVATGMCHTDLIVRDQYYPVPLPAVL 63
V +CK A F ++++++ P+ EV +K+VA G+C TD V PLPA+L
Sbjct 7 VIKCKAAVLWELKKPFSIEEVEVAPPKAQEVRIKMVAVGICGTDDHVVSGTMVTPLPAIL 66
Query 64 GHEGSGIIEAIGPNVKDLAVGDHVV-LSYGFCGSCEQCSSGQPAYCQDFFGRNFSGGDPD 122
GHE +GI+E++G V + GD V+ L+ CG C C + + YC N G D
Sbjct 67 GHEAAGIVESVGEGVTTVKPGDKVIPLAVPQCGKCRICKNPESNYCLKNDVSNPQGTLQD 126
Query 123 GHSAVCSHDHHKIHDHFFAQSSFATYAISRENNAVKVSKDVPLELLGPLGCGIQTGAGAA 182
G S IH HF S+F+ Y + EN K+ PL + +GCG TG G+A
Sbjct 127 GTSRFTCRGK-PIH-HFLGISTFSQYTVVDENAVAKIDAASPLAKVCLIGCGFSTGYGSA 184
Query 183 INALKVAPASSFVTWGAGAVGLSALLAAKVCGATTIIAVDIVESRLALAKELGATHVINS 242
+N KV P S+ +G G VGLS ++ K GA IIAVDI + + A AKELGAT IN
Sbjct 185 VNVAKVTPGSTCAVFGLGGVGLSVVMGCKAAGAARIIAVDINKDKFAKAKELGATECINP 244
Query 243 KTQD-PV-EAIKEITGGGVKFALESTGRPEILKQGIDAL-GILGSIAVVGAPPLGTTAAF 299
+ + P+ E +KE+T GGV F+ E GR + + + G+ +VG PP +
Sbjct 245 QDYNKPIQEVLKEMTDGGVDFSFEVIGRLDTMMASLLCCHEACGTSVIVGVPPDSQNLSM 304
Query 300 DVNDLLLGGKSIIGVVEGSGVPKKFIPALVSLYQQGKFPFDKLV-KFYDFKDINQAAIDS 358
+ LLL G++ G V G K+ +P LV+ + KF D L+ F+ IN
Sbjct 305 NPM-LLLTGRTWKGAVLGGFKSKECVPKLVADFMAKKFSLDALITHVLPFEKINDGFDLL 363
Query 359 HKGITLKPIL 368
H G +++ IL
Sbjct 364 HSGKSIRTIL 373
>Q17335 Alcohol dehydrogenase class-3 [Caenorhabditis elegans]
Length=384
Score = 195 bits (495), Expect = 3e-62
Identities = 129/373 (35%), Positives = 184/373 (49%), Gaps = 19/373 (5%)
Query 9 AAVTECKGADFELKQLKIREPQNDEVLVKIVATGMCHTDLIVRDQYYPVPL-PAVLGHEG 67
AAV A ++ +++ P+ EV VKI+ T +CHTD D + P L P VLGHEG
Sbjct 13 AAVAWSAKAPLSIETIQVAPPKAHEVRVKILYTAVCHTDAYTLDGHDPEGLFPVVLGHEG 72
Query 68 SGIIEAIGPNVKDLAVGDHVVLSY-GFCGSCEQCSSGQPAYCQDFFGRNFSGGDPDGHSA 126
SGI+E++G V A GDHVV Y C CE C + + CQ +G PDG S
Sbjct 73 SGIVESVGEGVTGFAPGDHVVPLYVPQCKECEYCKNPKTNLCQKIRISQGNGFMPDGSSR 132
Query 127 VCSHDHHKIHDHFFAQSSFATYAISRENNAVKVSKDVPLELLGPLGCGIQTGAGAAINAL 186
+ H F S+F+ Y + + + KV+ + PLE + LGCGI TG GA +N
Sbjct 133 FTCNGKQLFH--FMGCSTFSEYTVVADISLCKVNPEAPLEKVSLLGCGISTGYGAVLNTC 190
Query 187 KVAPASSFVTWGAGAVGLSALLAAKVCGATTIIAVDIVESRLALAKELGATHVINSKTQD 246
KV S+ WG GAVGL+ ++ AK GA I+ +D++ES+ AK GAT IN K+ +
Sbjct 191 KVEEGSTVAVWGLGAVGLAVIMGAKAAGAKKIVGIDLIESKFESAKFFGATECINPKSVE 250
Query 247 PVEA------IKEITGGGVKFALESTGRPEILKQGIDAL----GILGSIAVVGAPPLGTT 296
E + E GG + E G ++Q ++A G+ I V GA T
Sbjct 251 LPEGKSFQAWLVEQFDGGFDYTFECIGNVHTMRQALEAAHKGWGVSCIIGVAGAGQEIAT 310
Query 297 AAFDVNDLLLGGKSIIGVVEGSGVPKKFIPALVSLYQQGKFPFDKLVKF-YDFKDINQAA 355
F L+ G++ G G + +P LV Y K D+ + ++ DIN A
Sbjct 311 RPFQ----LVTGRTWKGTAFGGWKSVESVPRLVDDYMNKKLLIDEFITHRWNIDDINTAF 366
Query 356 IDSHKGITLKPIL 368
HKG +L+ +L
Sbjct 367 DVLHKGESLRSVL 379
>P86883 Alcohol dehydrogenase 1 [Columba livia]
Length=375
Score = 194 bits (494), Expect = 3e-62
Identities = 131/372 (35%), Positives = 191/372 (51%), Gaps = 9/372 (2%)
Query 3 KFTEITAAVTECKGADFELKQLKIREPQNDEVLVKIVATGMCHTD-LIVRDQYYPVPLPA 61
K AAV G ++++++ P+ EV +KIVATG+C TD +V+ V P
Sbjct 5 KVIRCRAAVAWAVGKPLSVEEVEVAPPKAGEVRIKIVATGICRTDDHVVKGCIANVEFPV 64
Query 62 VLGHEGSGIIEAIGPNVKDLAVGDHVV-LSYGFCGSCEQCSSGQPAYCQDFFGRNFSGGD 120
+ GHEG+GI+E+IG V + GD V+ L CG C C + + +YC
Sbjct 65 IPGHEGAGIVESIGEGVTSVKPGDKVIPLCIPNCGECTFCLNPEASYCVKSHFSEPQNLM 124
Query 121 PDGHSAVCSHDHHKIHDHFFAQSSFATYAISRENNAVKVSKDVPLELLGPLGCGIQTGAG 180
PD S +IH HF S+FA Y ++ E K+ PL+ + LGCG TG G
Sbjct 125 PDKTSRFTCKGK-QIH-HFMWVSTFAEYTVAPETAVAKIDSAAPLDKVCLLGCGFSTGYG 182
Query 181 AAINALKVAPASSFVTWGAGAVGLSALLAAKVCGATTIIAVDIVESRLALAKELGATHVI 240
AAIN KV P S+ +G G VGLS ++ KV GA+ IIA+DI + + A AKELGAT I
Sbjct 183 AAINTAKVKPGSTCAVFGLGGVGLSVVMGCKVAGASRIIAIDINKDKFAKAKELGATDCI 242
Query 241 NSKT-QDPV-EAIKEITGGGVKFALESTGRPEILKQGIDALGI-LGSIAVVGAPPLGTTA 297
N + P+ E + E+TG V ++ E GR + + + + + G +VG P
Sbjct 243 NPQDFNKPIQEVVTEMTGHEVDYSFEVIGRADTMIAALASCNMNTGVFVMVGVAPSDAVI 302
Query 298 AFDVNDLLLGGKSIIGVVEGSGVPKKFIPALVSLYQQGKFPFDKLVKF-YDFKDINQAAI 356
+ D LLL G++ G + G + FIP LVS Y + KF D L+ F +N+
Sbjct 303 SVDPL-LLLTGRTHKGTLVGGSKGRNFIPRLVSSYLEKKFNSDLLITHTLPFAKVNEGFA 361
Query 357 DSHKGITLKPIL 368
H G +++ +L
Sbjct 362 LLHAGKSIRTVL 373
>P80512 Alcohol dehydrogenase 1 [Naja naja]
Length=375
Score = 194 bits (493), Expect = 5e-62
Identities = 130/371 (35%), Positives = 193/371 (52%), Gaps = 16/371 (4%)
Query 11 VTECKGA-------DFELKQLKIREPQNDEVLVKIVATGMCHTDLIVRDQYYPVPLPAVL 63
V +CK A ++Q+++ P+ EV +KI+ATG+C +D V + +PLP VL
Sbjct 6 VIKCKAAIAWELNKPLSIEQIEVAPPKAHEVRIKILATGVCRSDEHVISGAFRMPLPMVL 65
Query 64 GHEGSGIIEAIGPNVKDLAVGDHVVLSYG-FCGSCEQCSSGQPAYCQDFFGRNFSGGDPD 122
GHE +G++E++G V + GD V+ + CG C C S + C + SG PD
Sbjct 66 GHEAAGVVESVGEGVTCVKPGDKVIPLFAPQCGKCRACQSPKGNLCTSNDLNSGSGLMPD 125
Query 123 GHSAVCSHDHHKIHDHFFAQSSFATYAISRENNAVKVSKDVPLELLGPLGCGIQTGAGAA 182
G S IH HF + S+F Y + EN+ VK+ PLE + +GCG TG GAA
Sbjct 126 GTSRFTCKGK-SIH-HFISTSTFTEYTVVHENSVVKIDPSAPLEKVCLIGCGFSTGYGAA 183
Query 183 INALKVAPASSFVTWGAGAVGLSALLAAKVCGATTIIAVDIVESRLALAKELGATHVINS 242
+ KV P S +G G VGLS ++ K GA+ II VDI + + A AKE+GAT IN
Sbjct 184 MQTAKVEPGSICAVFGLGGVGLSVVMGCKAAGASRIIGVDINKDKFAKAKEMGATECINP 243
Query 243 -KTQDPV-EAIKEITGG-GVKFALESTGRPEILKQGIDAL-GILGSIAVVGAPPLGTTAA 298
+ P+ E + ++TGG GV ++ E GR E + + LG+ VVG PP +
Sbjct 244 LDFKKPINEVLFDLTGGEGVDYSFEVIGRTETMISAFTSCHQNLGTSVVVGVPPNASMIT 303
Query 299 FDVNDLLLGGKSIIGVVEGSGVPKKFIPALVSLYQQGKFPFDKLVKF-YDFKDINQAAID 357
++ +L G++ G V G K +P LVS + Q KF D L+ F+ IN+
Sbjct 304 YNPL-MLFTGRTWKGCVFGGWKSKDSVPKLVSDFMQKKFVLDPLITHTLPFEKINEGFDL 362
Query 358 SHKGITLKPIL 368
G +++ +L
Sbjct 363 LRSGKSIRTVL 373
>P25405 Alcohol dehydrogenase 1A [Saara hardwickii]
Length=375
Score = 192 bits (489), Expect = 2e-61
Identities = 127/371 (34%), Positives = 191/371 (51%), Gaps = 16/371 (4%)
Query 11 VTECKGA-------DFELKQLKIREPQNDEVLVKIVATGMCHTDLIVRDQYYPVPLPAVL 63
V +CK A ++Q+++ P+ EV +KI+ATG+C +D V + +PLP VL
Sbjct 6 VIKCKAAIAWEIKKPLSIEQIEVAPPKAHEVRIKILATGICRSDDHVISGAFKMPLPMVL 65
Query 64 GHEGSGIIEAIGPNVKDLAVGDHVV-LSYGFCGSCEQCSSGQPAYCQDFFGRNFSGGDPD 122
GHE +G++E++G V + GD V+ L CG C C S + C +G PD
Sbjct 66 GHEAAGVVESVGEGVTCVKPGDKVIPLFVPQCGKCSSCRSTRGNLCTSNDLSAATGLMPD 125
Query 123 GHSAVCSHDHHKIHDHFFAQSSFATYAISRENNAVKVSKDVPLELLGPLGCGIQTGAGAA 182
G S K HF + SSF Y + EN+ VK+ PLE + +GCG TG GAA
Sbjct 126 GTSRFTCKG--KSLHHFISTSSFTEYTVVHENSVVKIDAAAPLEKVCLIGCGFSTGYGAA 183
Query 183 INALKVAPASSFVTWGAGAVGLSALLAAKVCGATTIIAVDIVESRLALAKELGATHVINS 242
+ KV P S+ +G G VGLSA++ K GA+ II VDI + + AKE+GAT +N
Sbjct 184 VETAKVEPGSTCAVFGLGGVGLSAVMGCKAAGASRIIGVDINKDKFPKAKEMGATECVNP 243
Query 243 -KTQDPV-EAIKEITGG-GVKFALESTGRPEILKQGIDALGI-LGSIAVVGAPPLGTTAA 298
+ P+ E + ++TGG GV ++ E GR + + + + + G+ +VG PP +
Sbjct 244 LDYKKPINEVLFDLTGGEGVDYSFEVIGRTDTMTAALASCHMDYGTSIIVGLPPSASEIT 303
Query 299 FDVNDLLLGGKSIIGVVEGSGVPKKFIPALVSLYQQGKFPFDKLVKF-YDFKDINQAAID 357
F L+ G++ G V G K +P LVS + Q KF D L+ F IN+
Sbjct 304 FSPG-LIFTGRTWKGSVFGGWKSKDSVPRLVSDFMQKKFSLDPLITHTMPFDKINEGFEL 362
Query 358 SHKGITLKPIL 368
G +++ +L
Sbjct 363 LRAGKSIRSVL 373
>P14139 All-trans-retinol dehydrogenase [NAD(+)] ADH1B [Papio
hamadryas]
Length=375
Score = 192 bits (488), Expect = 3e-61
Identities = 132/370 (36%), Positives = 189/370 (51%), Gaps = 15/370 (4%)
Query 11 VTECKGA-------DFELKQLKIREPQNDEVLVKIVATGMCHTDLIVRDQYYPVPLPAVL 63
V +CK A F ++ +++ P+ EV +K+VA G+C TD V PLPA+L
Sbjct 7 VIKCKAAVLWEVKKPFSIEDVEVAPPKAYEVRIKMVAVGICRTDDHVVSGNLVSPLPAIL 66
Query 64 GHEGSGIIEAIGPNVKDLAVGDHVV-LSYGFCGSCEQCSSGQPAYCQDFFGRNFSGGDPD 122
GHE +GI+E++G V + GD V+ L CG C C S + YC N G D
Sbjct 67 GHEAAGIVESVGEGVTTVKPGDKVIPLFTPQCGKCRVCKSPEGNYCVKNDLSNPRGTLQD 126
Query 123 GHSAVCSHDHHKIHDHFFAQSSFATYAISRENNAVKVSKDVPLELLGPLGCGIQTGAGAA 182
G IH HF S+F+ Y + EN K+ PLE + +GCG TG G+A
Sbjct 127 GTRRFTCRGK-PIH-HFVGTSTFSQYTVVDENAVAKIDAASPLEKVCLIGCGFSTGYGSA 184
Query 183 INALKVAPASSFVTWGAGAVGLSALLAAKVCGATTIIAVDIVESRLALAKELGATHVINS 242
+N KV P S +G G VGLSA++ K GA IIAVDI + + A AKELGAT IN
Sbjct 185 VNVAKVTPGSVCAVFGLGGVGLSAVMGCKAAGAARIIAVDINKDKFAKAKELGATECINP 244
Query 243 KT-QDPV-EAIKEITGGGVKFALESTGRPEILKQGIDAL-GILGSIAVVGAPPLGTTAAF 299
+ + P+ E +KE+T GGV F+ E GR + + + G+ +VG PP +
Sbjct 245 QDYKKPIQEVLKEMTDGGVDFSFEVIGRLDTMMASLLCCHEACGTSVIVGVPPDSQNLSI 304
Query 300 DVNDLLLGGKSIIGVVEGSGVPKKFIPALVSLYQQGKFPFDKLV-KFYDFKDINQAAIDS 358
+ LLL G++ G V G ++ IP LV+ + KF D L+ F+ IN+
Sbjct 305 NPM-LLLTGRTWKGAVYGGFKSREGIPKLVADFMAKKFSLDALITHVLPFEKINEGFDLL 363
Query 359 HKGITLKPIL 368
G +++ +L
Sbjct 364 RSGKSIRTVL 373
Lambda K H a alpha
0.320 0.139 0.413 0.792 4.96
Gapped
Lambda K H a alpha sigma
0.267 0.0410 0.140 1.90 42.6 43.6
Effective search space used: 1362075
Database: 900cda00dee352d27d0798827ebe7115.SwissProt.fasta
Posted date: May 15, 2024 6:39 PM
Number of letters in database: 4,802
Number of sequences in database: 13
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Neighboring words threshold: 11
Window for multiple hits: 40
Loading
Data ...
