BLASTP 2.12.0+
Reference: Stephen F. Altschul, Thomas L. Madden, Alejandro A.
Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J.
Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of
protein database search programs", Nucleic Acids Res. 25:3389-3402.
Reference for composition-based statistics: Alejandro A. Schaffer,
L. Aravind, Thomas L. Madden, Sergei Shavirin, John L. Spouge, Yuri
I. Wolf, Eugene V. Koonin, and Stephen F. Altschul (2001),
"Improving the accuracy of PSI-BLAST protein database searches with
composition-based statistics and other refinements", Nucleic Acids
Res. 29:2994-3005.
Database: e82a7fc520c5cd0a4bd088e9c3e9b875.SwissProt.fasta
17 sequences; 7,536 total letters
Query= ACIAD1467
Length=480
Score E
Sequences producing significant alignments: (Bits) Value
P0CI72 Isoxanthopterin deaminase [Unknown prokaryotic organism] 590 0.0
Q9I6Z0 8-oxoguanine deaminase [Pseudomonas aeruginosa (strain ATC... 273 5e-90
P95442 Hydroxydechloroatrazine ethylaminohydrolase [Pseudomonas s... 221 1e-69
Q2RJW1 5-methylthioadenosine/S-adenosylhomocysteine deaminase [Mo... 176 2e-53
B8FRL9 5-methylthioadenosine/S-adenosylhomocysteine deaminase [De... 168 2e-50
Q24UA2 5-methylthioadenosine/S-adenosylhomocysteine deaminase [De... 168 3e-50
Q3ITF7 5-methylthioadenosine/S-adenosylhomocysteine deaminase [Na... 166 1e-49
A5D1G6 5-methylthioadenosine/S-adenosylhomocysteine deaminase [Pe... 166 1e-49
Q9HN51 5-methylthioadenosine/S-adenosylhomocysteine deaminase [Ha... 165 3e-49
B1I2P4 5-methylthioadenosine/S-adenosylhomocysteine deaminase [De... 164 8e-49
P72156 Atrazine chlorohydrolase [Pseudomonas sp. (strain ADP)] 118 6e-32
Q9EYU0 Melamine deaminase [Paracidovorax citrulli] 117 2e-31
Q58936 5'-deoxyadenosine deaminase [Methanocaldococcus jannaschii... 115 3e-31
Q46812 Putative aminohydrolase SsnA [Escherichia coli (strain K12)] 90.9 8e-23
Q9R111 Guanine deaminase [Mus musculus] 83.6 2e-20
Q9X034 5-methylthioadenosine/S-adenosylhomocysteine deaminase [Th... 82.0 5e-20
P76641 Guanine deaminase [Escherichia coli (strain K12)] 81.3 1e-19
>P0CI72 Isoxanthopterin deaminase [Unknown prokaryotic organism]
Length=482
Score = 590 bits (1521), Expect = 0.0
Identities = 288/467 (62%), Positives = 358/467 (77%), Gaps = 4/467 (1%)
Query 5 LIKNAHSILTG---LAGDAARSNADCIRIENGIITELASALNSQPDEIIIDAKDCAIYPA 61
LI+NA +I+TG A D +R IRI I + AL +P E I+DA DC IYPA
Sbjct 11 LIRNAAAIMTGGRGTADDPSRVPGPDIRIVGDTIDAIG-ALAPRPGETIVDATDCVIYPA 69
Query 62 WVNTHHHLFQSLLKGEPQGLNQSLTPWLASTPYRFRGAFDEDSFRLAARIGLIELLRSGC 121
WVNTHHHLFQSLLKGEP GL+ +LTPWLA+TPYRFR FDE FRLAARIGLIEL RSGC
Sbjct 70 WVNTHHHLFQSLLKGEPAGLDATLTPWLAATPYRFRALFDERRFRLAARIGLIELARSGC 129
Query 122 ATVADHHYLYWPNMPFDGAEILFDEADQLGLRFILCRGGGTLTRGLEAELPQALRPEKFD 181
ATVADH+Y+Y+P MPFD + ILF+EA++LGLRF+L RGG T TR LEA+LP ALRPE D
Sbjct 130 ATVADHNYVYYPGMPFDSSAILFEEAEKLGLRFVLLRGGATQTRQLEADLPTALRPETLD 189
Query 182 SVIADVERLVSKYHDDSPQAFKRIVMAPTTALHSTTPEQLRETAQVARRLGIRLHSHLSE 241
+ +AD+ERL ++YHD SP+A +R+VMAPTT L+S +P ++RETA VARRLG+R+HSHLSE
Sbjct 190 AYVADIERLAARYHDASPRAMRRVVMAPTTVLYSISPREMRETAAVARRLGLRMHSHLSE 249
Query 242 TVDYLDAARAKFGMTPVQFCAEHDWIGEDVWFAHLVKLLPEEIQLLGQTKTGIAHCPQSN 301
TV Y D+A + +G +PV FC EHDW+G DVW+AHLVK+ +EI LL QT TG+AHCPQSN
Sbjct 250 TVGYQDSAYSMYGKSPVAFCGEHDWLGSDVWYAHLVKVDADEIALLAQTGTGVAHCPQSN 309
Query 302 ARLGSGIADLVALEQAGMNISIGVDGAASNEAADMLSETHAAWMLQRARKGMLAKPKYEG 361
RLGSGI + + AG+ +SIGVDGAASNEAADM+SE H W+ QRAR GMLA+P Y G
Sbjct 310 GRLGSGICPVREMADAGVPVSIGVDGAASNEAADMISEVHMTWLAQRARLGMLAQPAYRG 369
Query 362 GLFEGGADAATIEDVIRWGTHGGAQVLGLNEIGTLEVGQQADLVVYQLNDLRYMGLHDVA 421
G FEGGA AA+I +VI WGT GGA+V+GL+E+G + VG AD+ VY+L+D RY GLHD A
Sbjct 370 GSFEGGAGAASIAEVIHWGTAGGARVMGLDEVGKVAVGYAADIAVYRLDDPRYFGLHDPA 429
Query 422 IGPVASGGQAQIKHMLIGGKTVIENNQVPNLDILELAAQAREAVKKL 468
IGPVASGG+ + + GK V+ ++ + +DI EL +AR V++L
Sbjct 430 IGPVASGGRPSVMALFSAGKRVVVDDLIEGVDIKELGGEARRVVREL 476
>Q9I6Z0 8-oxoguanine deaminase [Pseudomonas aeruginosa (strain
ATCC 15692 / DSM 22644 / CIP 104116 / JCM 14847 / LMG 12228
/ 1C / PRS 101 / PAO1)]
Length=449
Score = 273 bits (698), Expect = 5e-90
Identities = 170/465 (37%), Positives = 248/465 (53%), Gaps = 26/465 (6%)
Query 6 IKNAHSILTGLAGDAARSNADCIRIENGIITELASALN--SQPDEIIIDAKDCAIYPAWV 63
I+N +I T DAA + +E+G I EL A +QP DA + P V
Sbjct 6 IRNPLAIFTANGLDAAGG----LVVEDGRIVELLGAGQQPAQPCASQFDASRHVVLPGLV 61
Query 64 NTHHHLFQSLLKGEPQGLNQSLTPWLASTPYRFRGAFDEDSFRLAARIGLIELLRSGCAT 123
NTHHH +Q+L + +NQ L PWL T Y + LA ++ L ELL SGC T
Sbjct 62 NTHHHFYQTLTRAWAPVVNQPLFPWL-KTLYPVWARLTPEKLELATKVALAELLLSGCTT 120
Query 124 VADHHYLYWPNMPFDGAEILFDEADQLGLRFILCRGGGTLTRGLEAELPQALRPEKFDSV 183
ADHHYL+ P ++ ++LG+R +L RG +L + LP ++ +++
Sbjct 121 AADHHYLF-PGGLEQAIDVQAGVVEELGMRAMLTRGSMSLGEK-DGGLPPQQTVQEAETI 178
Query 184 IADVERLVSKYHDDSPQAFKRIVMAPTTALHSTTPEQLRETAQVARRLGIRLHSHLSETV 243
+AD ERL+++YH A +I +AP + S TPE +R +A+VA R +RLH+HL+ET+
Sbjct 179 LADSERLIARYHQRGDGARVQIALAPCSPF-SVTPEIMRASAEVAARHDVRLHTHLAETL 237
Query 244 DYLDAARAKFGMTPVQFCAEHDWIGEDVWFAHLVKLLPEEIQLLGQTKTGIAHCPQSNAR 303
D D +FG+ V + W+G W AH + EEI+ LG+ TGI HCP SN R
Sbjct 238 DEEDFCLQRFGLRTVDYLDSVGWLGPRTWLAHGIHFNAEEIRRLGEAGTGICHCPSSNMR 297
Query 304 LGSGIADLVALEQAGMNISIGVDGAASNEAADMLSETHAAWMLQRARKGMLAKPKYEGGL 363
L SGI V LE AG I +GVDG+ASN+A++M+ E A LQR R
Sbjct 298 LASGICPTVELEAAGAPIGLGVDGSASNDASNMILEARQALYLQRLRY------------ 345
Query 364 FEGGADAATIEDVIRWGTHGGAQVLGLNEIGTLEVGQQADLVVYQLNDLRYMGLHDVAIG 423
GA+ T E + W T G A++LG ++IG L G+QADL +++L++LR+ G HD +
Sbjct 346 ---GAERITPELALGWATRGSARLLGRSDIGELAPGKQADLALFKLDELRFSGSHD-PLS 401
Query 424 PVASGGQAQIKHMLIGGKTVIENNQVPNLDILELAAQAREAVKKL 468
+ + +++GG + + V LD+ L A+ R A L
Sbjct 402 ALLLCAADRADRVMVGGAWRVVDGAVEGLDLAALIARHRAAASAL 446
>P95442 Hydroxydechloroatrazine ethylaminohydrolase [Pseudomonas
sp. (strain ADP)]
Length=481
Score = 221 bits (562), Expect = 1e-69
Identities = 140/415 (34%), Positives = 208/415 (50%), Gaps = 20/415 (5%)
Query 50 IIDAKDCAIYPAWVNTHHHLFQSLLKG-EPQGLNQ-SLTPWLASTPYRFRGAFDEDSFRL 107
+++ + YP +NTHHH FQ+ ++ P Q + WL Y DED
Sbjct 58 VVNCRGLTAYPGLINTHHHFFQAFVRNLAPLDWTQLDVLAWLRKI-YPVFALVDEDCIYH 116
Query 108 AARIGLIELLRSGCATVADHHYLYWPNMPFDGAEILFDEADQLGLRFILCRGGGTLTRGL 167
+ + + EL++ GC T DH Y Y + FD A+ LGLRF RG TL
Sbjct 117 STVVSMAELIKHGCTTAFDHQYNYSRRGGPFLVDRQFDAANLLGLRFHAGRGCITLPMAE 176
Query 168 EAELPQALRPEKFDSVIADVERLVSKYHDDSPQAFKRIVMAPTTALHSTTPEQLRETAQV 227
+ +P A+R E D+ +AD ERLVS++HD P A +R+V+AP++ + + PE E+A++
Sbjct 177 GSTIPDAMR-ESTDTFLADCERLVSRFHDPRPFAMQRVVVAPSSPVIAY-PETFVESARL 234
Query 228 ARRLGIRLHSHLSETVDYLDAARAKFGMTPVQFCAEHDWIGEDVWFAHLVKLLPEEIQLL 287
AR LG+ LH+HL E A A+FG + +C ++G DVW AH + +I L
Sbjct 235 ARHLGVSLHTHLGE--GETPAMVARFGERSLDWCENRGFVGPDVWLAHGWEFTAADIARL 292
Query 288 GQTKTGIAHCPQSNARLGSGIADLVALEQAGMNISIGVDGAASNEAADMLSETHAAWMLQ 347
T TG+AHCP +G+ + D+ A+ AG+ + GVDG ASN+++++ A++LQ
Sbjct 293 AATGTGVAHCPAPVFLVGAEVTDIPAMAAAGVRVGFGVDGHASNDSSNLAECIRLAYLLQ 352
Query 348 RARKGMLAKPKYEGGLFEGGADAATIEDVIRWGTHGGAQVLGLNEIGTLEVGQQADLVVY 407
+ P D +R T GGA L ++G L VG+ AD
Sbjct 353 CLKASERQHP------------VPAPYDFLRMATQGGADCLNRPDLGALAVGRAADFFAV 400
Query 408 QLNDLRYMGL-HDVAIGPVASGGQAQIKHMLIGGKTVIENNQVPNLDILELAAQA 461
LN + Y+G HD P G + +I GK V N + P LD +ELA A
Sbjct 401 DLNRIEYIGANHDPRSLPAKVGFSGPVDMTVINGKVVWRNGEFPGLDEMELARAA 455
>Q2RJW1 5-methylthioadenosine/S-adenosylhomocysteine deaminase
[Moorella thermoacetica (strain ATCC 39073 / JCM 9320)]
Length=428
Score = 176 bits (447), Expect = 2e-53
Identities = 129/425 (30%), Positives = 199/425 (47%), Gaps = 49/425 (12%)
Query 48 EIIIDAKDCAIYPAWVNTHHHLFQSLLKGEPQGLNQSLTPWLASTPYRFRGAFDEDSFRL 107
+ +IDA D P VN H H +LL+ L L WL + + +
Sbjct 47 DTVIDAGDMVALPGLVNAHTHAAMTLLRSYADDL--PLKQWLEEKIWPREDRLEREDIYW 104
Query 108 AARIGLIELLRSGCATVADHHYLYWPNMPFDGAEILFDEADQLGLRFILCRG----GGTL 163
++I L+E++RSG T AD +Y+ GA + + GLR LC+G T
Sbjct 105 GSKIALLEMIRSGTTTFAD---MYFHMDAVAGAVV------EAGLRASLCQGLIGLQDTS 155
Query 164 TRGLEAELPQALRPEKFDSVIADVERLVSKYHDDSPQAFKRIVMAPTTALHSTTPEQLRE 223
+ LEA + +V ++H M A ++ TPE L
Sbjct 156 NKRLEAGIS-----------------MVKEWHGAGEGRIT--TMLGPHAPNTCTPEYLTR 196
Query 224 TAQVARRLGIRLHSHLSETVDYLDAARAKFGMTPVQFCAEHDWIGEDVWFAHLVKLLPEE 283
A+ A LG+ LH HL+ET ++ +A++G TPV + + V AH V L EE
Sbjct 197 VAETAAGLGVGLHIHLAETRGEVEDVKARYGATPVALVNKLGLLDLPVLAAHCVHLTTEE 256
Query 284 IQLLGQTKTGIAHCPQSNARLGSGIADLVALEQAGMNISIGVDGAASNEAADMLSETHAA 343
I +L + K G+AHCP+SN +L SG+A + + AG+N++IG DGA+SN DM++ET A
Sbjct 257 IAILAEKKVGVAHCPESNLKLASGVAPVKEMLAAGVNVAIGTDGASSNNNLDMVAETRTA 316
Query 344 WMLQRARKGMLAKPKYEGGLFEGGADAATIEDVIRWGTHGGAQVLGL-NEIGTLEVGQQA 402
+L KG+ P + T GA+ LGL EIGTLE G++A
Sbjct 317 ALL---AKGITGDP-----------TVVPAHQALVMATLNGARALGLEKEIGTLEAGKKA 362
Query 403 DLVVYQLNDLRYMGLHDVAIGPVASGGQAQIKHMLIGGKTVIENNQVPNLDILELAAQAR 462
DL++ + M +DV V + + + +++ GK ++ +V LD E+ AQ
Sbjct 363 DLILVDMRQPHLMPPNDVEANLVYAARGSDVDTVIVNGKILMARGEVKTLDAEEIYAQVT 422
Query 463 EAVKK 467
+ + K
Sbjct 423 KRMHK 427
>B8FRL9 5-methylthioadenosine/S-adenosylhomocysteine deaminase
[Desulfitobacterium hafniense (strain DSM 10664 / DCB-2)]
Length=431
Score = 168 bits (426), Expect = 2e-50
Identities = 122/446 (27%), Positives = 198/446 (44%), Gaps = 44/446 (10%)
Query 28 IRIENG---IITELASALNSQPDEIIIDAKDCAIYPAWVNTHHHLFQSLLKGEPQGLNQS 84
I IEN + E SA +S + IID + + P +NTH H ++L+ L
Sbjct 25 IGIENDRILFVGEKGSAPDSFIPDQIIDLPEDVVMPGLINTHTHAAMTMLRSYADDL--P 82
Query 85 LTPWLASTPYRFRGAFDEDSFRLAARIGLIELLRSGCATVADHHYLYWPNMPFDGAEILF 144
L PWL + + F ++ + L E+++SG T+ D ++
Sbjct 83 LMPWLQTKIWPFEDKMSDEDIYWGTLLALGEMIQSGTTTMLD----------------MY 126
Query 145 DEADQLGLRFILCRGGGTLTRGLEAELPQALRPEKFDSVIADVERLVSKYHDDSPQAFKR 204
DQ+ + G L+RGL P R A+ LV YH +
Sbjct 127 ASMDQVAKAVLEAGTRGVLSRGLIGNAPNGER------AFAENMDLVKNYHGAGQGRIQ- 179
Query 205 IVMAPTTALHSTTPEQLRETAQVARRLGIRLHSHLSETVDYLDAARAKFGMTPVQFCAEH 264
VM A ++ + E L+ Q A RLG+ +H H++ET D + + ++G TPVQ+ E
Sbjct 180 -VMFGPHAPYTCSGEFLQRVKQEADRLGVGIHIHVAETEDEIKTIKEQYGKTPVQWLEEL 238
Query 265 DWIGEDVWFAHLVKLLPEEIQLLGQTKTGIAHCPQSNARLGSGIADLVALEQAGMNISIG 324
G V AH V L E+ +++ Q K IAH P+SN +L SG A + L G+ + +G
Sbjct 239 GLFGGHVVAAHCVHLTEEDQEIMAQNKVFIAHNPESNMKLNSGTAPIPELRSRGVVVGLG 298
Query 325 VDGAASNEAADMLSETHAAWMLQRARKGMLAKPKYEGGLFEGGADAATIEDVIRWGTHGG 384
DG +SN DM E +A Q+ KG A P YE V++ T G
Sbjct 299 TDGTSSNNNLDMFGEMRSAAFQQKLVKGATALPAYE---------------VLQMATVDG 343
Query 385 AQVLGLNEIGTLEVGQQADLVVYQLNDLRYMGLHDVAIGPVASGGQAQIKHMLIGGKTVI 444
A+ LGL+++G L G +ADL+ + + + V ++ +++ GK ++
Sbjct 344 ARTLGLHDVGVLAPGYKADLISINFDQPHFYPRFSIPAHLVYVAHAGDVRTVMVDGKILM 403
Query 445 ENNQVPNLDILELAAQAREAVKKLQQ 470
+ Q+ +DI + + + K + Q
Sbjct 404 QERQLMTIDIKRVCREVEKRAKGIAQ 429
>Q24UA2 5-methylthioadenosine/S-adenosylhomocysteine deaminase
[Desulfitobacterium hafniense (strain Y51)]
Length=431
Score = 168 bits (425), Expect = 3e-50
Identities = 122/446 (27%), Positives = 198/446 (44%), Gaps = 44/446 (10%)
Query 28 IRIENG---IITELASALNSQPDEIIIDAKDCAIYPAWVNTHHHLFQSLLKGEPQGLNQS 84
I IEN + E SA +S + IID + + P +NTH H ++L+ L
Sbjct 25 IGIENDRILFVGEKGSAPDSFIPDQIIDLPEDVVMPGLINTHTHAAMTMLRSYADDL--P 82
Query 85 LTPWLASTPYRFRGAFDEDSFRLAARIGLIELLRSGCATVADHHYLYWPNMPFDGAEILF 144
L PWL + + F ++ + L E+++SG T+ D ++
Sbjct 83 LMPWLQTKIWPFEDKMSDEDIYWGTLLALGEMIQSGTTTMLD----------------MY 126
Query 145 DEADQLGLRFILCRGGGTLTRGLEAELPQALRPEKFDSVIADVERLVSKYHDDSPQAFKR 204
DQ+ + G L+RGL P R A+ LV YH +
Sbjct 127 ASMDQVAKAVLEAGTRGVLSRGLIGNAPNGER------AFAENIDLVKNYHGAGQGRIQ- 179
Query 205 IVMAPTTALHSTTPEQLRETAQVARRLGIRLHSHLSETVDYLDAARAKFGMTPVQFCAEH 264
VM A ++ + E L+ Q A RLG+ +H H++ET D + + ++G TPVQ+ E
Sbjct 180 -VMFGPHAPYTCSGEFLQRVKQEADRLGVGIHIHVAETEDEIKTIKEQYGKTPVQWLEEL 238
Query 265 DWIGEDVWFAHLVKLLPEEIQLLGQTKTGIAHCPQSNARLGSGIADLVALEQAGMNISIG 324
G V AH V L E+ +++ Q K IAH P+SN +L SG A + L G+ + +G
Sbjct 239 GLFGGHVVAAHCVHLTEEDQEIMAQNKVFIAHNPESNMKLNSGTAPIPELRSRGVVVGLG 298
Query 325 VDGAASNEAADMLSETHAAWMLQRARKGMLAKPKYEGGLFEGGADAATIEDVIRWGTHGG 384
DG +SN DM E +A Q+ KG A P YE V++ T G
Sbjct 299 TDGTSSNNNLDMFGEMRSAAFQQKLVKGATALPAYE---------------VLQMATVDG 343
Query 385 AQVLGLNEIGTLEVGQQADLVVYQLNDLRYMGLHDVAIGPVASGGQAQIKHMLIGGKTVI 444
A+ LGL+++G L G +ADL+ + + + V ++ +++ GK ++
Sbjct 344 ARTLGLHDVGVLAPGYKADLISINFDQPHFYPRFSIPAHLVYVAHAGDVRTVMVDGKILM 403
Query 445 ENNQVPNLDILELAAQAREAVKKLQQ 470
+ Q+ +DI + + + K + Q
Sbjct 404 QERQLMTIDIKRVCREVEKRAKGIAQ 429
>Q3ITF7 5-methylthioadenosine/S-adenosylhomocysteine deaminase
[Natronomonas pharaonis (strain ATCC 35678 / DSM 2160 / CIP
103997 / JCM 8858 / NBRC 14720 / NCIMB 2260 / Gabara)]
Length=431
Score = 166 bits (421), Expect = 1e-49
Identities = 122/423 (29%), Positives = 198/423 (47%), Gaps = 38/423 (9%)
Query 51 IDAKDCAIYPAWVNTHHHLFQSLLKGEPQGLNQSLTPWLASTPYRFRGAFDEDSFRLAAR 110
+DA+ C + P VNTH H +LL+G ++ L WL + + R R
Sbjct 45 LDAEGCLVVPGLVNTHCHAAMTLLRGYAD--DKPLDRWLQEDIWPVEAELTPEDIRAGTR 102
Query 111 IGLIELLRSGCATVADHHYLYWPNMPFDGAEILFDEADQLGLRFILCRGGGTLTRGLEAE 170
+GL+ELL++G V D ++ +P A + ++ G+R L G G +T G +
Sbjct 103 LGLVELLKNGVTAVGDMYF----EVPEVAAAV-----EEAGIRARL--GHGIVTVGKDEA 151
Query 171 LPQALRPEKFDSVIADVERLVSKYHDDSPQAFKRIVMAPTTALHSTTPEQLRETAQVARR 230
+A F+ +A V++ D + R + P + L + P+ + E AR
Sbjct 152 DARA----DFEEGLA-----VARELDGAADGRVRTALMPHS-LTTADPDLIAEFVPRARD 201
Query 231 LGIRLHSHLSETVDYLDAARAKFGMTPVQFCAEHDWIGEDVWFAHLVKLLPEEIQLLGQT 290
G+ +H H +ET D +D + G+ P++F E + E + AH V + EI+LL +
Sbjct 202 AGVPIHYHANETTDEVDPIVDERGVRPLEFADELGLLDEGDFIAHGVHVDETEIELLAER 261
Query 291 KTGIAHCPQSNARLGSGIADLVALEQAGMNISIGVDGAASNEAADMLSETHAAWMLQRAR 350
G+AHCP SN +L SGIA + AG+ + IG DG ASN D++ E A M+
Sbjct 262 GVGVAHCPASNMKLASGIAPVQEFLDAGVTVGIGTDGPASNNDLDVVDEMRDAAMV---- 317
Query 351 KGMLAKPKYEGGLFEGGADAATIEDVIRWGTHGGAQVLGLNEIGTLEVGQQADLVVYQLN 410
G L A A D++ T GGA+ LG + G +E G ADL + L+
Sbjct 318 ----------GKLGADDAAAVAAPDIVNAATAGGAETLGF-DAGRVEAGALADLAIVDLD 366
Query 411 DLRYMGLHDVAIGPVASGGQAQIKHMLIGGKTVIENNQVPNLDILELAAQAREAVKKLQQ 470
HD+ + + ++H ++GG+ ++E+ +V LD + +A +L
Sbjct 367 APHLTPSHDLVSHLAYAVRGSDVRHTVVGGEVIVEDREVRTLDAGAVKREAERHAAELVS 426
Query 471 RAE 473
RAE
Sbjct 427 RAE 429
>A5D1G6 5-methylthioadenosine/S-adenosylhomocysteine deaminase
[Pelotomaculum thermopropionicum (strain DSM 13744 / JCM 10971
/ SI)]
Length=433
Score = 166 bits (421), Expect = 1e-49
Identities = 121/422 (29%), Positives = 194/422 (46%), Gaps = 42/422 (10%)
Query 51 IDAKDCAIYPAWVNTHHHLFQSLLKGEPQGLNQSLTPWLASTPYRFRGAFDEDSFRLAAR 110
ID P +VN H H +LL+ + L WL+ + +
Sbjct 52 IDGTGMVAMPGFVNCHTHAAMTLLRSYADDM--PLMKWLSEKIWPVEERLQPEDIYWGTM 109
Query 111 IGLIELLRSGCATVADHHYLYWPNMPFDGAEILFDEADQLGLRFILCRGGGTLTRGLEAE 170
+ +E+++SG T AD ++ E + ++ G+R L RG + G
Sbjct 110 LCCLEMIKSGTTTFADMYF---------SMERVAAAVEESGMRACLSRGMIGVGSGARKA 160
Query 171 LPQALRPEKFDSVIADVERLVSKYHDDSPQAFKRIVMAPTTALHSTTPEQLRETAQVARR 230
+ ++L + + AD R+ + + +P ++ PE L++ +A R
Sbjct 161 IDESLSFVREWNGGAD-GRITAMFGPHAP--------------YTCPPEYLKKVVDLAAR 205
Query 231 LGIRLHSHLSETVDYLDAARAKFGMTPVQFCAEHDWIGEDVWFAHLVKLLPEEIQLLGQT 290
G +H H++ET D ++ RA +G TPV++ V AH V L +I++L
Sbjct 206 EGAGIHIHVAETRDEIEQIRAGYGTTPVRYLDAAGVFELPVLAAHCVHLDEGDIEILSAK 265
Query 291 KTGIAHCPQSNARLGSGIADLVALEQAGMNISIGVDGAASNEAADMLSETHAAWMLQRAR 350
+ GIAHCP+SN +L SGIA + L QAG + +G DGAASN DML E +A +L +
Sbjct 266 RVGIAHCPESNMKLASGIAPVTELLQAGAAVGLGTDGAASNNNLDMLEEMRSASLLHKVS 325
Query 351 KG-MLAKPKYEGGLFEGGADAATIEDVIRWGTHGGAQVLGLNEIGTLEVGQQADLVVYQL 409
G LA P +E +R T GGA LGL ++G L+ G +ADL++
Sbjct 326 TGDPLALPSFE---------------ALRMATAGGALALGLKDVGLLKPGMKADLILVDF 370
Query 410 NDLRYMGLHDVAIGPVASGGQAQIKHMLIGGKTVIENNQVPNLDILELAAQAREAVKKLQ 469
HD+ V + A + ++I GK V+E QV NLD ++ A+A++ +L
Sbjct 371 RRPHLCPQHDLIAHLVYAAQSADVDTVIINGKVVMEKRQVLNLDEEKIMAEAQKRALRLV 430
Query 470 QR 471
R
Sbjct 431 NR 432
>Q9HN51 5-methylthioadenosine/S-adenosylhomocysteine deaminase
[Halobacterium salinarum (strain ATCC 700922 / JCM 11081 /
NRC-1)]
Length=431
Score = 165 bits (418), Expect = 3e-49
Identities = 125/424 (29%), Positives = 196/424 (46%), Gaps = 42/424 (10%)
Query 51 IDAKDCAIYPAWVNTHHHLFQSLLKGEPQGLNQSLTPWLASTPYRFRGAFDEDSFRLAAR 110
+DA C + P VN H H+ +LL+G ++ L WL + + R AR
Sbjct 46 VDAAGCLVMPGLVNAHCHVAMTLLRGYAD--DKQLDAWLQEDIWPAEAELADGDIRAGAR 103
Query 111 IGLIELLRSGCATVADHHYLYWPNMPFDGAEILFDEADQLGLRFILCRGGGTLTRGLEAE 170
+GL+E++R+G AD M F+ E++ D + GLR + G G +T G +
Sbjct 104 LGLVEMIRAGTTAFAD--------MYFEVPEVV-DAITEAGLRARV--GHGVVTVGKDDA 152
Query 171 LPQALRPEKFDSVIADVERLVSKYHDDSPQAFKRIVMAPTT-ALHSTTPEQLRETAQVAR 229
+AD E +S + + A RI A +L + E LRE AR
Sbjct 153 -----------DAVADNEEALSVAREFNDAADGRITSAYMPHSLTTVGEEYLREFVAAAR 201
Query 230 RLGIRLHSHLSETVDYLDAARAKFGMTPVQFCAEHDWIGEDVWFAHLVKLLPEEIQLLGQ 289
+ +H H +ET ++ + G P+++ A+ + ED + AH V EI+LL +
Sbjct 202 EADVPVHFHANETEQEVEPIVDEHGSRPLEYAADVGLLAEDDFLAHGVHTTAGEIELLAE 261
Query 290 TKTGIAHCPQSNARLGSGIADLVALEQAGMNISIGVDGAASNEAADMLSETHAAWMLQRA 349
+ + HCP SN +L SG+A + A+ +AG+ +++G DGAASN D+ E A ML
Sbjct 262 SGASVVHCPASNMKLASGMAPVQAMREAGVTVALGTDGAASNNDLDVFDELRDAAML--- 318
Query 350 RKGMLAKPKYEGGLFEGGADAATIEDVIRWGTHGGAQVLGLNEIGTLEVGQQADLVVYQL 409
G L G ADA + T GGA LG + G +EVG ADL V
Sbjct 319 -----------GKLQTGAADAVPARAAVEMATAGGAAALGFDS-GRIEVGANADLAVVDF 366
Query 410 NDLRYMGLHD-VAIGPVASGGQAQIKHMLIGGKTVIENNQVPNLDILELAAQAREAVKKL 468
+ +HD V+ A+ GQ ++H + G+ ++ + +V D + QA + +L
Sbjct 367 DAPHLTPVHDHVSHLAYAATGQ-DVRHTICDGEVLMRDREVLPFDEAAVREQAAQRASEL 425
Query 469 QQRA 472
RA
Sbjct 426 AARA 429
>B1I2P4 5-methylthioadenosine/S-adenosylhomocysteine deaminase
[Desulforudis audaxviator (strain MP104C)]
Length=430
Score = 164 bits (415), Expect = 8e-49
Identities = 133/475 (28%), Positives = 214/475 (45%), Gaps = 57/475 (12%)
Query 2 MKYLIKNAHSILTG---LAGDAARSNADCIRIENGIITELASALNSQPDEI----IIDAK 54
M+ LI+NA+ I GD A +E G I A + P IDA
Sbjct 1 MRLLIRNAYVIPVAGSDFTGDVA--------VEEGRIV-FAGPTGAVPGTFEADETIDAT 51
Query 55 DCAIYPAWVNTHHHLFQSLLKGEPQGLNQSLTPWLASTPYRFRGAFDEDSFRLAARIGLI 114
P VN H H +L +G L L WL + D + + +
Sbjct 52 GMVATPGLVNCHTHAAMTLFRGYADDL--PLMEWLTRKIWPVENLLTGDDIYWGSLLAGL 109
Query 115 ELLRSGCATVADHHYLYWPNMPFDGAEILFDEADQLGLRFILCRGGGTLTRGLEAELPQA 174
E+L+SG T AD ++ + + +++GLR LCRG ++
Sbjct 110 EMLKSGTTTFADQYF---------EMDRVAQAVEEIGLRASLCRGLIGVS---------- 150
Query 175 LRPEKFDSVIADVERLVSKYHDDSPQAFKRIVMAPTTALHSTTPEQLRETAQVARRLGIR 234
E + +A+ V ++H + A + M A ++ P L++ + L +
Sbjct 151 ---EHAEKALAEGCEFVRRWHGAA--AGRISAMLGPHAPYTCPPAYLKKVVAASEELDVG 205
Query 235 LHSHLSETVDYLDAARAKFGMTPVQFCAEHDWIGEDVWFAHLVKLLPEEIQLLGQTKTGI 294
LH HLSET ++ +A++G +P+ E V AH V L +I++L + G+
Sbjct 206 LHIHLSETRTEIEQIKAEYGCSPIALMEETGLFHRPVLAAHCVHLSEADIKILARRGVGV 265
Query 295 AHCPQSNARLGSGIADLVALEQAGMNISIGVDGAASNEAADMLSETHAAWMLQRARKGML 354
AH PQSN +L SGIA +V + AG+ + IG DGAASN +M+ E A +LQ+ +G
Sbjct 266 AHNPQSNMKLASGIAPVVRMLAAGVRVGIGTDGAASNNDLNMVEEMRTAALLQKVAQG-- 323
Query 355 AKPKYEGGLFEGGADAATIEDVIRWGTHGGAQVLGLNE-IGTLEVGQQADLVVYQLNDLR 413
+ + G V+ T GGA+VLGL + IGTLEVG++AD+V++++N
Sbjct 324 -----DPTVLPAGL-------VLEMATAGGARVLGLEDRIGTLEVGKRADVVLWRVNQPH 371
Query 414 YMGLHDVAIGPVASGGQAQIKHMLIGGKTVIENNQVPNLDILELAAQAREAVKKL 468
H+ V S G+A + +++ G V+ +V +D + QA ++L
Sbjct 372 LCPAHNYQAHLVYSAGRADVDTVIVDGHVVMRGRRVLTVDEETVLRQAERTARRL 426
>P72156 Atrazine chlorohydrolase [Pseudomonas sp. (strain ADP)]
Length=474
Score = 118 bits (295), Expect = 6e-32
Identities = 117/466 (25%), Positives = 204/466 (44%), Gaps = 41/466 (9%)
Query 28 IRIENGIITELASALNSQPD--EIIIDAKDCAIYPAWVNTHHHLFQSLLKGEPQGLNQSL 85
+ +++G I L S P + +IDA+ + P ++N H H+ Q LL+G P Q
Sbjct 26 VHVQDGRIVALGVHAESVPPPADRVIDARGKVVLPGFINAHTHVNQILLRGGPSHGRQ-F 84
Query 86 TPWLASTPYRFRGAFDEDSFRLAARIGLIELLRSGCATVADH--HYLYWPNMPFDGAEIL 143
WL + Y + A + +A R+ E +RSG T+ ++ +Y N+ + A +
Sbjct 85 YDWLFNVVYPGQKAMRPEDVAVAVRLYCAEAVRSGITTINENADSAIYPGNI--EAAMAV 142
Query 144 FDEADQLGLRFILCRGGGTLTRG--------LEAELPQALRPEKFDSVIADVERLVSKYH 195
+ E +G+R + R G L+A PQ + +R+ +
Sbjct 143 YGE---VGVRVVYARMFFDRMDGRIQGYVDALKARSPQVELCSIMEETAVAKDRITALSD 199
Query 196 DDSPQAFKRIVMAPTTALHST-TPEQLRETAQVARRLGIRLHSHLSETVDYLDAARAKFG 254
A RI + P A + T E +R AR + H++E+ D G
Sbjct 200 QYHGTAGGRISVWPAPATTTAVTVEGMRWAQAFARDRAVMWTLHMAES----DHDERIHG 255
Query 255 MTPVQFCAEHDWIGEDVWFAHLVKLLPEEIQLLGQTKTGIAHCPQSNARLGSGIADLVAL 314
M+P ++ + + E + AH V ++++LL + +A SNA LGSG+A + +
Sbjct 256 MSPAEYMECYGLLDERLQVAHCVYFDRKDVRLLHRHNVKVASQVVSNAYLGSGVAPVPEM 315
Query 315 EQAGMNISIGVDGAASNEAADMLSETHAAWMLQRARKGMLAKPKYEGGLFEGGADAATIE 374
+ GM + IG D SN++ +M+ + + RA AD T E
Sbjct 316 VERGMAVGIGTDNGNSNDSVNMIGDMKFMAHIHRA--------------VHRDADVLTPE 361
Query 375 DVIRWGTHGGAQVLGL-NEIGTLEVGQQADLVVYQLNDLRYMGLHDVAIGPVASGGQAQI 433
++ T GA+ LG+ +EIG++E G++ADL++ L + H +A V ++
Sbjct 362 KILEMATIDGARSLGMDHEIGSIETGKRADLILLDLRHPQTTPHHHLAATIVFQAYGNEV 421
Query 434 KHMLIGGKTVIENNQ---VPNLDILELAAQAREAVKKLQQRAEKMA 476
+LI G V+EN + +P L +A+ + QRA +A
Sbjct 422 DTVLIDGNVVMENRRLSFLPPERELAFLEEAQSRATAILQRANMVA 467
>Q9EYU0 Melamine deaminase [Paracidovorax citrulli]
Length=474
Score = 117 bits (292), Expect = 2e-31
Identities = 117/466 (25%), Positives = 204/466 (44%), Gaps = 41/466 (9%)
Query 28 IRIENGIITELASALNSQPD--EIIIDAKDCAIYPAWVNTHHHLFQSLLKGEPQGLNQSL 85
+ +++G I L S P + +IDA+ + P ++N H H+ Q LL+G P Q L
Sbjct 26 VHVQDGRIVALGVHAESVPPPADRVIDARGKVVLPGFINAHTHVNQILLRGGPSHGRQ-L 84
Query 86 TPWLASTPYRFRGAFDEDSFRLAARIGLIELLRSGCATVADH--HYLYWPNMPFDGAEIL 143
WL + Y + A + +A R+ E +RSG T+ D+ +Y N+ + A +
Sbjct 85 YDWLFNVLYPGQKAMRPEDVAVAVRLYCAEAVRSGITTINDNADSAIYPGNI--EAAMAV 142
Query 144 FDEADQLGLRFILCRGGGTLTRG--------LEAELPQALRPEKFDSVIADVERLVSKYH 195
+ E +G+R + R G L+A PQ + +R+ +
Sbjct 143 YGE---VGVRVVYARMFFDRMDGRIQGYVDALKARSPQVELCSIMEETAVAKDRITALSD 199
Query 196 DDSPQAFKRIVMAPTTALH-STTPEQLRETAQVARRLGIRLHSHLSETVDYLDAARAKFG 254
A RI + P A+ + T E +R AR + H++E+ D
Sbjct 200 QYHGTAGGRISVWPAPAITPAVTVEGMRWAQAFARDRAVMWTLHMAES----DHDERLHW 255
Query 255 MTPVQFCAEHDWIGEDVWFAHLVKLLPEEIQLLGQTKTGIAHCPQSNARLGSGIADLVAL 314
M+P ++ + + E + AH V ++++LL + +A SNA LGSG+A + +
Sbjct 256 MSPAEYMECYGLLDERLQVAHCVYFDRKDVRLLHRHNVKVASQVVSNAYLGSGVAPVPEM 315
Query 315 EQAGMNISIGVDGAASNEAADMLSETHAAWMLQRARKGMLAKPKYEGGLFEGGADAATIE 374
+ GM + IG D N++ +M+ + + RA AD T E
Sbjct 316 VERGMAVGIGTDDGNCNDSVNMIGDMKFMAHIHRA--------------VHRDADVLTPE 361
Query 375 DVIRWGTHGGAQVLGL-NEIGTLEVGQQADLVVYQLNDLRYMGLHDVAIGPVASGGQAQI 433
++ T GA+ LG+ +EIG++E G++ADL++ L + H +A V ++
Sbjct 362 KILEMATIDGARSLGMDHEIGSIETGKRADLILLDLRHPQTTPHHHLAATIVFQAYGNEV 421
Query 434 KHMLIGGKTVIENNQ---VPNLDILELAAQAREAVKKLQQRAEKMA 476
+LI G V+EN + +P L +A+ + QRA +A
Sbjct 422 DTVLIDGNVVMENRRLSFLPPERELAFLEEAQSRATAILQRANMVA 467
>Q58936 5'-deoxyadenosine deaminase [Methanocaldococcus jannaschii
(strain ATCC 43067 / DSM 2661 / JAL-1 / JCM 10045 / NBRC
100440)]
Length=420
Score = 115 bits (288), Expect = 3e-31
Identities = 105/424 (25%), Positives = 184/424 (43%), Gaps = 47/424 (11%)
Query 50 IIDAKDCAIYPAWVNTHHHLFQSLLKGEPQGLNQSLTPWLASTPYRFRGAFDEDSFRLAA 109
IID K+ P +NTH H+ +L +G L L WL + + +E+
Sbjct 39 IIDGKNKIAIPGLINTHTHIPMTLFRGVADDL--PLMEWLNNYIWPMEAKLNEEIVYWGT 96
Query 110 RIGLIELLRSGCATVADHHYLYWPNMPFDGAEILFDEADQLGLRFILCRGGGTL--TRGL 167
+G IE++RSG T D ++ E + D+ G+R +L G L
Sbjct 97 LLGCIEMIRSGTTTFNDMYFFL---------EGIAKAVDESGMRAVLAYGMIDLFDEERR 147
Query 168 EAELPQALRPEKFDSVIADVERLVSKYHDDSPQAFKRIVMA-PTTALHSTTPEQLRETAQ 226
E EL A EK+ + I + RI+ A A ++ + E L E
Sbjct 148 ERELKNA---EKYINYINSLNN-------------SRIMPALGPHAPYTCSKELLMEVNN 191
Query 227 VARRLGIRLHSHLSETVDYLDAARAKFGMTPVQFCAEHDWIGE-DVWFAHLVKLLPEEIQ 285
+A++ + +H HL+ET+D + + K GM P + + + AH V L EEI+
Sbjct 192 LAKKYNVPIHIHLNETLDEIKMVKEKTGMEPFIYLNSFGFFDDVRAIAAHCVHLTDEEIK 251
Query 286 LLGQTKTGIAHCPQSNARLGSGIADLVALEQAGMNISIGVDGAASNEAADMLSETHAAWM 345
++ Q ++H P SN +L SG+A + L G+N+++G DG SN ++ E + +
Sbjct 252 IMKQKNINVSHNPISNLKLASGVAPIPKLLAEGINVTLGTDGCGSNNNLNLFEEIKVSAI 311
Query 346 LQRARKGMLAKPKYEGGLFEGGADAATIEDVIRWGTHGGAQVLGLNEIGTLEVGQQADLV 405
L KG+ P E+ + T GA+ L + + G + G AD+V
Sbjct 312 L---HKGVNLNP-----------TVVKAEEAFNFATKNGAKALNI-KAGEIREGYLADIV 356
Query 406 VYQLNDLRYMGLHDVAIGPVASGGQAQIKHMLIGGKTVIENNQVPNLDILELAAQAREAV 465
+ L D Y+ + + + + ++I G V+ + ++ +D ++ +A E
Sbjct 357 LINL-DKPYLYPKENIMSHLVYAFNGFVDDVIIDGNIVMRDGEILTVDEEKVYEKAEEMY 415
Query 466 KKLQ 469
+ L+
Sbjct 416 EILR 419
Score = 20.4 bits (41), Expect = 2.1
Identities = 16/52 (31%), Positives = 22/52 (42%), Gaps = 2/52 (4%)
Query 3 KYLIKNAHSILTGLAGDAARSNAD--CIRIENGIITELASALNSQPDEIIID 52
K L A I G D N D + + I++ L A N D++IID
Sbjct 338 KALNIKAGEIREGYLADIVLINLDKPYLYPKENIMSHLVYAFNGFVDDVIID 389
>Q46812 Putative aminohydrolase SsnA [Escherichia coli (strain
K12)]
Length=442
Score = 90.9 bits (224), Expect = 8e-23
Identities = 114/459 (25%), Positives = 185/459 (40%), Gaps = 49/459 (11%)
Query 28 IRIENGIITELASALNSQ-PDEIIIDAKDCAIYPAWVNTHHHLFQSLLKGEPQGLNQ--S 84
I IEN +I + AL + PD + + P V +H+H + L +G +
Sbjct 23 IAIENDVIVAIGDALTQRYPDASFKEMHGRIVMPGIVCSHNHFYSGLSRGIMANIAPCPD 82
Query 85 LTPWLASTPYRFRGAFDEDSFRLAARIGLIELLRSGCATVADHHYLYWPNMPFDGAEILF 144
L + +R A DE+S + I +E ++SGC +V DHH P L
Sbjct 83 FISTLKNLWWRLDRALDEESLYYSGLICSLEAIKSGCTSVIDHHAS--PAYIGGSLSTLR 140
Query 145 DEADQLGLRFILCRGGGTLTRGLEAELPQALRPE-KFDSVIADVERLVSK-YHDDSPQAF 202
D ++GLR + C G++ EL + + +F +I + ++ S+ Y ++
Sbjct 141 DAFLKVGLRAMTCFETTDRNNGIK-ELQEGVEENIRFARLIDEAKKATSEPYLVEAHIGA 199
Query 203 KRIVMAPTTALHSTTPEQLRETAQVARRLGIRLHSHLSETVDYLDAARAKFGMTPVQFCA 262
P L E LRE + G LH H +E + + + +G + A
Sbjct 200 HAPFTVPDAGL-----EMLREAVKAT---GRGLHIHAAEDLYDVSYSHHWYGKDLLARLA 251
Query 263 EHDWIGEDVWFAHLVKLLPEEIQLLGQTKTGIAHCPQSNARLGSG----IADLVALEQAG 318
+ D I AH + L ++I LL Q + H +SN G ++D+
Sbjct 252 QFDLIDSKTLVAHGLYLSKDDITLLNQRDAFLVHNARSNMNNHVGYNHHLSDI------- 304
Query 319 MNISIGVDGAASNEAADMLSETHAAWMLQRARKGMLAKPKYEGGLFEGGADAATIEDVIR 378
N+++G DG S DM E A+ R G L + L G
Sbjct 305 RNLALGTDGIGS----DMFEEMKFAFFKHRDAGGPLWPDSFAKALTNGNE---------L 351
Query 379 WGTHGGAQVLGLNEIGTLEVGQQADLVVYQLNDLRYMGLHDVAIGPVASG-GQAQIKHML 437
+ GA + G LE G +ADL + N + L D G +A G G + ++
Sbjct 352 MSRNFGA------KFGLLEAGYKADLTICDYNSPTPL-LADNIAGHIAFGMGSGSVHSVM 404
Query 438 IGGKTVIENNQVPNLDILELAAQAREAVKKLQQRAEKMA 476
+ G V E+ Q N D + AQAR+A + +R + +A
Sbjct 405 VNGVMVYEDRQF-NFDCDSIYAQARKAAASMWRRMDALA 442
>Q9R111 Guanine deaminase [Mus musculus]
Length=454
Score = 83.6 bits (205), Expect = 2e-20
Identities = 99/404 (25%), Positives = 168/404 (42%), Gaps = 50/404 (12%)
Query 60 PAWVNTHHHLFQSLLKGEPQGLNQSLTPWLAS----TPYRFRGA-FDEDSFRLAARIGLI 114
P V+TH H Q G ++ L WL T RFR E+ + R
Sbjct 76 PGLVDTHIHAPQYAFAGS--NVDLPLLEWLNKYTFPTEQRFRSTDVAEEVYTRVVR---- 129
Query 115 ELLRSGCATVADHHYLYWPNMPFDGAEILFDEADQLGLRFILCRGGGTLTRGLEAELPQA 174
L++G T Y+ + D + IL + D+ G R + G + L +P+
Sbjct 130 RTLKNGTTTAC-----YFGTIHTDSSLILAEITDKFGQRAFV----GKVCMDLNDTVPEY 180
Query 175 LRPEKFDSVIADVERLVSKYHDDSPQAFKRIVMAPTTALHSTTPEQLRETAQVARRLGIR 234
E + + + ER VS+ + K IV T S T + E +A+ +
Sbjct 181 --KETTEESVKETERFVSEMLQKNYPRVKPIVTPRFTL--SCTETLMSELGNIAKTHDLY 236
Query 235 LHSHLSETVDYLDAARAKFGMTP--VQFCAEHDWIGEDVWFAHLVKLLPEEIQLLGQTKT 292
+ SH+SE + ++A ++ + +++ + AH L EE+ + +
Sbjct 237 IQSHISENREEIEAVKSLYPSYKNYTDVYDKNNLLTNKTVMAHGCYLSEEELNIFSERGA 296
Query 293 GIAHCPQSNARLGSGIADLVALEQAGMNISIGVDGAASNEAADMLSETHAAWMLQRARKG 352
IAHCP SN L SG+ +++ + + + I +G D A + ML A M+
Sbjct 297 SIAHCPNSNLSLSSGLLNVLEVLKHKVKIGLGTD-VAGGYSYSMLDAIRRAVMVSNV--- 352
Query 353 MLAKPKYEGGLFEGGADAATIEDVIRWGTHGGAQVLGL-NEIGTLEVGQQAD--LVVYQL 409
+L E L T+++V R T GG+Q LGL +EIG EVG++ D L+ +
Sbjct 353 LLINKVNEKNL--------TLKEVFRLATLGGSQALGLDSEIGNFEVGKEFDALLINPRA 404
Query 410 NDLRYMGLHDVAIGPVAS---------GGQAQIKHMLIGGKTVI 444
+D + +G ++ G I+ + +GGK V+
Sbjct 405 SDSPIDLFYGDFVGDISEAVIQKFLYLGDDRNIEEVYVGGKQVV 448
>Q9X034 5-methylthioadenosine/S-adenosylhomocysteine deaminase
[Thermotoga maritima (strain ATCC 43589 / DSM 3109 / JCM 10099
/ NBRC 100826 / MSB8)]
Length=406
Score = 82.0 bits (201), Expect = 5e-20
Identities = 104/451 (23%), Positives = 173/451 (38%), Gaps = 78/451 (17%)
Query 28 IRIENGIITELASALNSQPDEIIIDAKDCAIYPAWVNTHHHLFQSLLKGEPQGLNQSLTP 87
+ IENG I + ++ +D + PA NTH H +LL+G + L S
Sbjct 21 VEIENGTIKRVLQG----EVKVDLDLSGKLVMPALFNTHTHAPMTLLRGVAEDL--SFEE 74
Query 88 WLASTPYRFRGAFDEDSFRLAARIGLIELLRSGCATVADHHYLYWPNMPFDGAEILFDEA 147
WL S E + +E+ R G A D ++ E +
Sbjct 75 WLFSKVLPIEDRLTEKMAYYGTILAQMEMARHGIAGFVDMYF---------HEEWIAKAV 125
Query 148 DQLGLRFILCRG--------GGTLTRGLEAELPQALRPEKFDSVIADVERLVSKYHDDSP 199
G+R +L RG GG L L +L ++++
Sbjct 126 RDFGMRALLTRGLVDSNGDDGGRLEENL---------------------KLYNEWNGFEG 164
Query 200 QAFKRIVMAPTTALHSTTPEQLRETAQVARRLGIRLHSHLSETV--DYLDAARAKFGMTP 257
+ F + P + + + E L+ A+ L + HL ET +Y G+
Sbjct 165 RIF--VGFGPHSP-YLCSEEYLKRVFDTAKSLNAPVTIHLYETSKEEYDLEDILNIGLKE 221
Query 258 VQFCAEHDWIGEDVWFAHLVKLLPEEIQLLGQTKTGIAHCPQSNARLGSGIADLVALEQA 317
V+ A AH V L +L ++H P SN +LG+GIA + + +
Sbjct 222 VKTIA-----------AHCVHLPERYFGVLKDIPFFVSHNPASNLKLGNGIAPVQRMIEH 270
Query 318 GMNISIGVDGAASNEAADMLSETHAAWMLQRARKGMLAKPKYEGGLFEGGADAATIEDVI 377
GM +++G DGAASN + ++ E A +LQ+A+ P+ + +
Sbjct 271 GMKVTLGTDGAASNNSLNLFFEMRLASLLQKAQ-----NPR-----------NLDVNTCL 314
Query 378 RWGTHGGAQVLGLNEIGTLEVGQQADLVVYQLNDLRYMGLHDVAIGPVASGGQAQIKHML 437
+ T+ GAQ +G G +E G ADLVV L DL M + ++ +
Sbjct 315 KMVTYDGAQAMGFKS-GKIEEGWNADLVVIDL-DLPEMFPVQNIKNHLVHAFSGEVFATM 372
Query 438 IGGKTVIENNQVPNLDILELAAQAREAVKKL 468
+ GK + + + P +D E+ + K+L
Sbjct 373 VAGKWIYFDGEYPTIDSEEVKRELARIEKEL 403
>P76641 Guanine deaminase [Escherichia coli (strain K12)]
Length=439
Score = 81.3 bits (199), Expect = 1e-19
Identities = 103/419 (25%), Positives = 171/419 (41%), Gaps = 57/419 (14%)
Query 46 PDEIII-DAKDCAIYPAWVNTHHHLFQSLLKGEPQGLNQSLTPWLASTPYRFRGAFDEDS 104
PD I + D + I P +V+TH H QS + G + L WL + +++
Sbjct 61 PDTIRVRDYRGKLIVPGFVDTHIHYPQSEMVG---AYGEQLLEWLNKHTFPTERRYEDLE 117
Query 105 F-RLAARIGLIELLRSGCATVADHHYLYWPNMPFDGAEILFDEADQLGLRFILCRGGGTL 163
+ R + + +LLR+G T L + + + LF+ A + +R I G +
Sbjct 118 YAREMSAFFIKQLLRNGTTTA-----LVFGTVHPQSVDALFEAASHINMRMI---AGKVM 169
Query 164 TRGLEAELPQALRPEKFDSVIADVERLVSKYHDDSPQAFKRIVMAPTTALHSTT-PEQLR 222
++ P L + +S + L+ ++H + R++ A T T+ PEQ+
Sbjct 170 ---MDRNAPDYLL-DTAESSYHQSKELIERWHKNG-----RLLYAITPRFAPTSSPEQMA 220
Query 223 ETAQVARRL-GIRLHSHLSETVDYLDAARAKFGMTPVQFCAEHDW--IGEDVWFAHLVKL 279
++ +H+HL E D + ++ + H + G++ FAH V L
Sbjct 221 MAQRLKEEYPDTWVHTHLCENKDEIAWVKSLYPDHDGYLDVYHQYGLTGKNCVFAHCVHL 280
Query 280 LPEEIQLLGQTKTGIAHCPQSNARLGSGIADLVALEQAGMNISIGVDGAASN--EAADML 337
+E L +TK+ IA CP SN LGSG+ +L Q + + +G D A L
Sbjct 281 EEKEWDRLSETKSSIAFCPTSNLYLGSGLFNLKKAWQKKVKVGMGTDIGAGTTFNMLQTL 340
Query 338 SETHAAWMLQRARKGMLAKPKYEGGLFEGGADAATIEDVIRWGTHGGAQVLGLNE-IGTL 396
+E + LQ R + + T GGA+ LGL++ IG
Sbjct 341 NEAYKVLQLQGYR--------------------LSAYEAFYLATLGGAKSLGLDDLIGNF 380
Query 397 EVGQQADLVVYQ-----LNDLRY---MGLHDVAIGPVASGGQAQIKHMLIGGKTVIENN 447
G++AD VV + L LRY + L D + G I + G+ V E N
Sbjct 381 LPGKEADFVVMEPTATPLQQLRYDNSVSLVDKLFVMMTLGDDRSIYRTYVDGRLVYERN 439
Lambda K H a alpha
0.321 0.136 0.405 0.792 4.96
Gapped
Lambda K H a alpha sigma
0.267 0.0410 0.140 1.90 42.6 43.6
Effective search space used: 2847056
Database: e82a7fc520c5cd0a4bd088e9c3e9b875.SwissProt.fasta
Posted date: May 9, 2024 12:09 PM
Number of letters in database: 7,536
Number of sequences in database: 17
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Neighboring words threshold: 11
Window for multiple hits: 40
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Data ...
