BLASTP 2.12.0+
Reference: Stephen F. Altschul, Thomas L. Madden, Alejandro A.
Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J.
Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of
protein database search programs", Nucleic Acids Res. 25:3389-3402.
Reference for composition-based statistics: Alejandro A. Schaffer,
L. Aravind, Thomas L. Madden, Sergei Shavirin, John L. Spouge, Yuri
I. Wolf, Eugene V. Koonin, and Stephen F. Altschul (2001),
"Improving the accuracy of PSI-BLAST protein database searches with
composition-based statistics and other refinements", Nucleic Acids
Res. 29:2994-3005.
Database: a8c07e3f8693469cb0249d4e104b22f4.SwissProt.fasta
19 sequences; 13,456 total letters
Query= ACIAD1488
Length=715
Score E
Sequences producing significant alignments: (Bits) Value
Q933I3 Leukotoxin translocation ATP-binding protein LktB [Mannhei... 295 9e-93
Q93FH6 Leukotoxin translocation ATP-binding protein LktB [Mannhei... 291 2e-91
P16532 Leukotoxin translocation ATP-binding protein LktB [Mannhei... 291 2e-91
Q9RCG7 Exotoxin translocation ATP-binding protein PaxB [Pasteurel... 291 3e-91
P23702 Leukotoxin export ATP-binding protein LtxB [Aggregatibacte... 291 5e-91
Q93FH2 Leukotoxin translocation ATP-binding protein LktB [Mannhei... 291 5e-91
Q933E0 Leukotoxin translocation ATP-binding protein LktB [Biberst... 290 9e-91
P0C086 Leukotoxin translocation ATP-binding protein LktB [Mannhei... 290 1e-90
Q93FH0 Leukotoxin translocation ATP-binding protein LktB [Mannhei... 290 1e-90
Q93FH3 Leukotoxin translocation ATP-binding protein LktB [Mannhei... 290 1e-90
P0C087 Leukotoxin translocation ATP-binding protein LktB [Mannhei... 290 1e-90
Q93FG6 Leukotoxin translocation ATP-binding protein LktB [Mannhei... 286 3e-89
Q46717 Alpha-hemolysin translocation ATP-binding protein HlyB [Es... 284 1e-88
Q04473 Toxin RTX-III translocation ATP-binding protein [Actinobac... 283 4e-88
Q47258 Alpha-hemolysin translocation ATP-binding protein HlyB [Es... 281 3e-87
P10089 Alpha-hemolysin translocation ATP-binding protein HlyB [Es... 281 3e-87
P0DKX6 Cyclolysin secretion/processing ATP-binding protein CyaB [... 281 3e-87
P08716 Alpha-hemolysin translocation ATP-binding protein HlyB [Es... 280 4e-87
P55122 Leukotoxin translocation ATP-binding protein LktB [Pasteur... 279 1e-86
>Q933I3 Leukotoxin translocation ATP-binding protein LktB [Mannheimia
glucosida]
Length=708
Score = 295 bits (756), Expect = 9e-93
Identities = 193/691 (28%), Positives = 345/691 (50%), Gaps = 8/691 (1%)
Query 12 LQAVLTIARHYRIESSEERIRLQLDWNQNQNPEEVLELMCRQVGLSLRVAKFNSDLLNPW 71
L A+ +A+++ I + E I+ + D + N L + + L + K L+
Sbjct 12 LVALTMLAQYHNISLNPEEIKHKFDLDGNGLSLTSWLLAAKSLALKAKHIKKEISRLHLV 71
Query 72 RLPVIAEFKDGQIGVVDKADTEGNVSIQLSGDHGLSQSFAIDSLKGLIKHIYIMRPESSI 131
LP + +G+ ++ K DT+ N + + + Q + D + + I+
Sbjct 72 NLPALVWQDNGKHFLLVKVDTDNNRYLTYNLEQDAPQILSQDEFEACYQGQLILVTSR-- 129
Query 132 PDARVDEYIKPYEANWFWSIVLKDWKRYIDIMFASLIANILALATIIFSMQVYDRVVPSQ 191
A V + ++ WF V+K K +++ + S+ I AL T +F V D+V+ +
Sbjct 130 --ASVVGQLAKFDFTWFIPAVIKYRKIFLETLIVSIFLQIFALITPLFFQVVMDKVLVHR 187
Query 192 SIPTLWVLAGGVFIAAIFEFVLRVSRIYLSDIIGKRADLKISDRVFGHALRIK-NKERSK 250
TL ++ + I IFE VL R Y+ R D+++ ++F H L + + ++
Sbjct 188 GFSTLNIITVALAIVIIFEIVLSGLRTYVFSHSTSRIDVELGAKLFRHLLSLPISYFENR 247
Query 251 STGTFISQIRELEGVRELVTSTTITAIADLPFFLLFLVILWIIGGHVFWVVVIMVPLMIL 310
G ++++REL+ +R +T +T++ DL F +F ++W + V++ +P IL
Sbjct 248 RVGDTVARVRELDQIRNFLTGQALTSVLDLLFSFIFFAVMWYYSPKLTLVILGSLPCYIL 307
Query 311 PGILAQKKLAKLAQEGMRESAIRNAILVEAVQGIEDIKLLRAESRFQNQWNHMNELSADY 370
I L + E SA A LVE+V I IK + + + W+
Sbjct 308 WSIFISPILRRRLDEKFARSADNQAFLVESVTAINMIKAMAVAPQMTDTWDKQLASYVSS 367
Query 371 SMQQRKIVGVLSAWTQKLQGLTYALVVLVGCFAVMDGEMTTGALVACSILSSRMLGPISQ 430
S + + + Q +Q + + +G V+ G+++ G L+A ++LS +++ P+ +
Sbjct 368 SFRVTVLATIGQQGVQLIQKTVMVINLWLGAHLVISGDLSIGQLIAFNMLSGQVIAPVIR 427
Query 431 ITGVLGRLQQAKVAKQSLDELMKKPVDQPDRAHLVHKPVIHGDYDLSNVVFQYNPEDSKP 490
+ + QQ ++ L +++ P +Q + P I GD N+ F+Y P D+
Sbjct 428 LAQLWQDFQQVGISVTRLGDVLNSPTEQYQGK--LSLPEIQGDIAFKNIRFRYKP-DAPT 484
Query 491 NLAIQKLRIKAGEKIAILGRNGAGKSTLLQLLSGMQSPINGKLTLDDLELSLIDPADIRR 550
L L IK GE I I+GR+G+GKSTL +LL P NG++ +D +L+L DP +RR
Sbjct 485 ILNNVNLEIKKGEVIGIVGRSGSGKSTLTKLLQRFYIPENGQVLIDGHDLALADPNWLRR 544
Query 551 DMGLLNQNASLFYGTIRENLTLGAPLANDHEIIKALKVTGALSFVEEKKEGLDHIILEGG 610
+G++ Q+ L +IREN+ L P + +I A K+ GA F+ E +EG + I+ E G
Sbjct 545 QIGVVLQDNVLLNRSIRENIALSEPGMSMERVIYAAKLAGAHDFISELREGYNTIVGEQG 604
Query 611 VGFSGGQRQALLLARLLIRQPNILLLDEPTAAIDDVSEKQLIDHLKQWLAHRTLVVATHR 670
G SGGQRQ + +AR L+ P IL+ DE T+A+D SE ++ ++++ RT+++ HR
Sbjct 605 AGLSGGQRQRIAIARALVNNPKILIFDEATSALDYESEHIIMQNMQKICQGRTVILIAHR 664
Query 671 RAVLELVDRIIVINDGKIVMDGPRDQILKQS 701
+ ++ DRIIV+ G+IV G ++L+ S
Sbjct 665 LSTVKNADRIIVMEKGEIVEQGKHHELLQNS 695
>Q93FH6 Leukotoxin translocation ATP-binding protein LktB [Mannheimia
haemolytica]
Length=708
Score = 291 bits (746), Expect = 2e-91
Identities = 191/691 (28%), Positives = 343/691 (50%), Gaps = 8/691 (1%)
Query 12 LQAVLTIARHYRIESSEERIRLQLDWNQNQNPEEVLELMCRQVGLSLRVAKFNSDLLNPW 71
L A+ +A+++ I + E I+ + D + L + + L + K L+
Sbjct 12 LVALTMLAQYHNISLNPEEIKHKFDLDGKGLSLTAWLLAAKSLALKAKHIKKEISRLHLV 71
Query 72 RLPVIAEFKDGQIGVVDKADTEGNVSIQLSGDHGLSQSFAIDSLKGLIKHIYIMRPESSI 131
LP + +G+ ++ K DT+ N + + + Q + D + + I+
Sbjct 72 NLPALVWQDNGKHFLLVKVDTDNNRYLTYNLEQDAPQILSQDEFEACYQGQLILVTSR-- 129
Query 132 PDARVDEYIKPYEANWFWSIVLKDWKRYIDIMFASLIANILALATIIFSMQVYDRVVPSQ 191
A V + ++ WF V+K K +++ + S+ I AL T +F V D+V+ +
Sbjct 130 --ASVVGQLAKFDFTWFIPAVIKYRKIFLETLIVSIFLQIFALITPLFFQVVMDKVLVHR 187
Query 192 SIPTLWVLAGGVFIAAIFEFVLRVSRIYLSDIIGKRADLKISDRVFGHALRIK-NKERSK 250
TL ++ + I IFE VL R Y+ R D+++ ++F H L + + ++
Sbjct 188 GFSTLNIITVALAIVIIFEIVLSGLRTYVFSHSTSRIDVELGAKLFRHLLSLPISYFENR 247
Query 251 STGTFISQIRELEGVRELVTSTTITAIADLPFFLLFLVILWIIGGHVFWVVVIMVPLMIL 310
G ++++REL+ +R +T +T++ DL F +F ++W + V++ +P IL
Sbjct 248 RVGDTVARVRELDQIRNFLTGQALTSVLDLLFSFIFFAVMWYYSPKLTLVILGSLPCYIL 307
Query 311 PGILAQKKLAKLAQEGMRESAIRNAILVEAVQGIEDIKLLRAESRFQNQWNHMNELSADY 370
I L + E SA A LVE+V I IK + + + W+
Sbjct 308 WSIFISPILRRRLDEKFARSADNQAFLVESVTAINMIKAMAVAPQMTDTWDKQLASYVSS 367
Query 371 SMQQRKIVGVLSAWTQKLQGLTYALVVLVGCFAVMDGEMTTGALVACSILSSRMLGPISQ 430
S + + + Q +Q + + +G V+ G+++ G L+A ++LS +++ P+ +
Sbjct 368 SFRVTVLATIGQQGVQLIQKTVMVINLWLGAHLVISGDLSIGQLIAFNMLSGQVIAPVIR 427
Query 431 ITGVLGRLQQAKVAKQSLDELMKKPVDQPDRAHLVHKPVIHGDYDLSNVVFQYNPEDSKP 490
+ + QQ ++ L +++ P +Q + P I GD N+ F+Y P D+
Sbjct 428 LAQLWQDFQQVGISVTRLGDVLNSPTEQYQGK--LSLPEIKGDISFKNIRFRYKP-DAPT 484
Query 491 NLAIQKLRIKAGEKIAILGRNGAGKSTLLQLLSGMQSPINGKLTLDDLELSLIDPADIRR 550
L L I+ GE I I+GR+G+GKSTL +LL P NG++ +D +L+L DP +RR
Sbjct 485 ILNNVNLEIRQGEVIGIVGRSGSGKSTLTKLLQRFYIPENGQVLIDGHDLALADPNWLRR 544
Query 551 DMGLLNQNASLFYGTIRENLTLGAPLANDHEIIKALKVTGALSFVEEKKEGLDHIILEGG 610
+G++ Q+ L +IREN+ L P +I A K+ GA F+ E +EG + I+ E G
Sbjct 545 QIGVVLQDNVLLNRSIRENIALSDPGMPMERVIYAAKLAGAHDFISELREGYNTIVGEQG 604
Query 611 VGFSGGQRQALLLARLLIRQPNILLLDEPTAAIDDVSEKQLIDHLKQWLAHRTLVVATHR 670
G SGGQRQ + +AR L+ P IL+ DE T+A+D SE ++ ++++ RT+++ HR
Sbjct 605 AGLSGGQRQRIAIARALVNNPKILIFDEATSALDYESEHIIMQNMQKICQGRTVILIAHR 664
Query 671 RAVLELVDRIIVINDGKIVMDGPRDQILKQS 701
+ ++ DRIIV+ G+IV G ++L+ S
Sbjct 665 LSTVKNADRIIVMEKGEIVEQGKHHELLQNS 695
>P16532 Leukotoxin translocation ATP-binding protein LktB [Mannheimia
haemolytica]
Length=708
Score = 291 bits (746), Expect = 2e-91
Identities = 191/691 (28%), Positives = 343/691 (50%), Gaps = 8/691 (1%)
Query 12 LQAVLTIARHYRIESSEERIRLQLDWNQNQNPEEVLELMCRQVGLSLRVAKFNSDLLNPW 71
L A+ +A+++ I + E I+ + D + L + + L + K L+
Sbjct 12 LVALTMLAQYHNISLNPEEIKHKFDLDGKGLSLTAWLLAAKSLALKAKHIKKEISRLHLV 71
Query 72 RLPVIAEFKDGQIGVVDKADTEGNVSIQLSGDHGLSQSFAIDSLKGLIKHIYIMRPESSI 131
LP + +G+ ++ K DT+ N + + + Q + D + + I+
Sbjct 72 NLPALVWQDNGKHFLLVKVDTDNNRYLTYNLEQDAPQILSQDEFEACYQGQLILVTSR-- 129
Query 132 PDARVDEYIKPYEANWFWSIVLKDWKRYIDIMFASLIANILALATIIFSMQVYDRVVPSQ 191
A V + ++ WF V+K K +++ + S+ I AL T +F V D+V+ +
Sbjct 130 --ASVVGQLAKFDFTWFIPAVIKYRKIFLETLIVSIFLQIFALITPLFFQVVMDKVLVHR 187
Query 192 SIPTLWVLAGGVFIAAIFEFVLRVSRIYLSDIIGKRADLKISDRVFGHALRIK-NKERSK 250
TL ++ + I IFE VL R Y+ R D+++ ++F H L + + ++
Sbjct 188 GFSTLNIITVALAIVIIFEIVLSGLRTYVFSHSTSRIDVELGAKLFRHLLSLPISYFENR 247
Query 251 STGTFISQIRELEGVRELVTSTTITAIADLPFFLLFLVILWIIGGHVFWVVVIMVPLMIL 310
G ++++REL+ +R +T +T++ DL F +F ++W + V++ +P IL
Sbjct 248 RVGDTVARVRELDQIRNFLTGQALTSVLDLLFSFIFFAVMWYYSPKLTLVILGSLPCYIL 307
Query 311 PGILAQKKLAKLAQEGMRESAIRNAILVEAVQGIEDIKLLRAESRFQNQWNHMNELSADY 370
I L + E SA A LVE+V I IK + + + W+
Sbjct 308 WSIFISPILRRRLDEKFARSADNQAFLVESVTSINMIKAMAVAPQMTDTWDKQLASYVSS 367
Query 371 SMQQRKIVGVLSAWTQKLQGLTYALVVLVGCFAVMDGEMTTGALVACSILSSRMLGPISQ 430
S + + + Q +Q + + +G V+ G+++ G L+A ++LS +++ P+ +
Sbjct 368 SFRVTVLATIGQQGVQLIQKTVMVINLWLGAHLVISGDLSIGQLIAFNMLSGQVIAPVIR 427
Query 431 ITGVLGRLQQAKVAKQSLDELMKKPVDQPDRAHLVHKPVIHGDYDLSNVVFQYNPEDSKP 490
+ + QQ ++ L +++ P +Q + P I GD N+ F+Y P D+
Sbjct 428 LAQLWQDFQQVGISVTRLGDVLNSPTEQYQGK--LSLPEIKGDISFKNIRFRYKP-DAPT 484
Query 491 NLAIQKLRIKAGEKIAILGRNGAGKSTLLQLLSGMQSPINGKLTLDDLELSLIDPADIRR 550
L L I+ GE I I+GR+G+GKSTL +LL P NG++ +D +L+L DP +RR
Sbjct 485 ILNNVNLEIRQGEVIGIVGRSGSGKSTLTKLLQRFYIPENGQVLIDGHDLALADPNWLRR 544
Query 551 DMGLLNQNASLFYGTIRENLTLGAPLANDHEIIKALKVTGALSFVEEKKEGLDHIILEGG 610
+G++ Q+ L +IREN+ L P +I A K+ GA F+ E +EG + I+ E G
Sbjct 545 QIGVVLQDNVLLNRSIRENIALSDPGMPMERVIYAAKLAGAHDFISELREGYNTIVGEQG 604
Query 611 VGFSGGQRQALLLARLLIRQPNILLLDEPTAAIDDVSEKQLIDHLKQWLAHRTLVVATHR 670
G SGGQRQ + +AR L+ P IL+ DE T+A+D SE ++ ++++ RT+++ HR
Sbjct 605 AGLSGGQRQRIAIARALVNNPKILIFDEATSALDYESEHIIMQNMQKICQGRTVILIAHR 664
Query 671 RAVLELVDRIIVINDGKIVMDGPRDQILKQS 701
+ ++ DRIIV+ G+IV G ++L+ S
Sbjct 665 LSTVKNADRIIVMEKGEIVEQGKHHELLQNS 695
>Q9RCG7 Exotoxin translocation ATP-binding protein PaxB [Pasteurella
aerogenes]
Length=711
Score = 291 bits (746), Expect = 3e-91
Identities = 193/692 (28%), Positives = 350/692 (51%), Gaps = 14/692 (2%)
Query 12 LQAVLTIARHYRIESSEERIRLQLDWNQNQNPEEVLELMCRQVGLSLRVAKFNSDLLNPW 71
L A++ +A+++ I S E I+ + D L + L + K + D L
Sbjct 15 LHALVILAQYHNIAVSPEEIKHKFDPEGKGIDLVAWLLAAKSFELKAKKVKKSIDRLPFI 74
Query 72 RLPVIAEFKDGQIGVVDKADTEGNVSIQLSGDHGLSQSFAIDSLKGLIK-HIYIMRPESS 130
LP + DGQ ++ K DT+ N + + + + + + + ++ ++ +S
Sbjct 75 HLPALIWRDDGQHFILTKIDTQTNRYLIFDLEERNPKVLSAVEFQQVFQGNVILLTSRAS 134
Query 131 IPDARVDEYIKPYEANWFWSIVLKDWKRYIDIMFASLIANILALATIIFSMQVYDRVVPS 190
I + ++ WF ++K K ++++M S+ + AL T +F V D+V+
Sbjct 135 IMGK-----LAKFDFTWFIPAIIKYRKIFVEVMIVSIFLQLFALITPLFFQVVMDKVLVH 189
Query 191 QSIPTLWVLAGGVFIAAIFEFVLRVSRIYLSDIIGKRADLKISDRVFGHALRIK-NKERS 249
+ TL V+ + I IFE VL R Y+ R D+++ ++F H L + + +
Sbjct 190 RGFSTLNVITVALAIVVIFEIVLSGLRTYVFSHSTSRIDVELGAKLFRHLLALPISYFEN 249
Query 250 KSTGTFISQIRELEGVRELVTSTTITAIADLPFFLLFLVILWIIGGHVFWVVVIMVPLMI 309
+ G ++++REL+ +R +T +T++ DL F +F ++W + V+++ +P I
Sbjct 250 RRVGDTVARVRELDQIRNFLTGQALTSVLDLLFSFIFFAVMWYYSPKLTIVILLSLPCYI 309
Query 310 LPGILAQKKLAKLAQEGMRESAIRNAILVEAVQGIEDIKLLRAESRFQNQWNHM--NELS 367
I L + E +A A LVE+V I+ IK L + N W+ + +S
Sbjct 310 AWSIFISPILRRRLDEKFTRNADNQAFLVESVTAIDTIKALAVTPQMTNIWDKQLASYVS 369
Query 368 ADYSMQQRKIVGVLSAWTQKLQGLTYALVVLVGCFAVMDGEMTTGALVACSILSSRMLGP 427
AD+ + +G Q +Q + + +G V+ G+++ G L+A ++LS +++ P
Sbjct 370 ADFRVTVLATIG--QQGVQLIQKTVMIINLWLGAHLVISGDLSIGQLIAFNMLSGQVIAP 427
Query 428 ISQITGVLGRLQQAKVAKQSLDELMKKPVDQPDRAHLVHKPVIHGDYDLSNVVFQYNPED 487
+ ++ + QQ ++ L +++ P + + P I+GD N+ F+Y P D
Sbjct 428 VIRLAQLWQDFQQVGISITRLGDVLNAPTENFQGK--LSLPEINGDVTFKNIRFRYKP-D 484
Query 488 SKPNLAIQKLRIKAGEKIAILGRNGAGKSTLLQLLSGMQSPINGKLTLDDLELSLIDPAD 547
+ L L IK GE I I+GR+G+GKSTL +LL P NG++ +D +L+L DP
Sbjct 485 APIILNDVNLTIKQGEVIGIVGRSGSGKSTLTKLLQRFYIPENGQVLIDGHDLALADPNW 544
Query 548 IRRDMGLLNQNASLFYGTIRENLTLGAPLANDHEIIKALKVTGALSFVEEKKEGLDHIIL 607
+RR +G++ Q+ L +IR+N+ L P ++I A K+ GA F+ E +EG + ++
Sbjct 545 LRRQIGVVLQDNVLLNRSIRDNIALTDPSMPMEQVIHAAKLAGAHDFISELREGYNTMVG 604
Query 608 EGGVGFSGGQRQALLLARLLIRQPNILLLDEPTAAIDDVSEKQLIDHLKQWLAHRTLVVA 667
E G G SGGQRQ + +AR L+ P IL+ DE T+A+D SE ++ +++Q RT+++
Sbjct 605 EQGAGLSGGQRQRIAIARALVNNPRILIFDEATSALDYESEHIIMRNMQQICHGRTVIII 664
Query 668 THRRAVLELVDRIIVINDGKIVMDGPRDQILK 699
HR + + DRIIV+ G IV G ++L+
Sbjct 665 AHRLSTVRKADRIIVMEKGHIVERGKHSELLE 696
>P23702 Leukotoxin export ATP-binding protein LtxB [Aggregatibacter
actinomycetemcomitans]
Length=707
Score = 291 bits (744), Expect = 5e-91
Identities = 194/692 (28%), Positives = 351/692 (51%), Gaps = 14/692 (2%)
Query 12 LQAVLTIARHYRIESSEERIRLQLDWNQNQNPEEVLELMCRQVGLSLRVAKFNSDLLNPW 71
LQA+ +A+++ I + E I+ + D + + + L + +GL +R A D L
Sbjct 11 LQALEVLAQYHNISINPEEIKHKFDIDGHGLNQTKWLLAAKSLGLKVRTANKTVDRLPFL 70
Query 72 RLPVIAEFKDGQIGVVDKADTEGNVSIQLSGDHGLSQSFAIDSLKGLIKHIYIMRPESSI 131
LP +A DG+ ++ K D E + + L Q I K + Y +
Sbjct 71 HLPALAWRDDGEHFILLKIDQETDRYLIFD----LIQKNPIVLDKNEFEERYQSKVILIA 126
Query 132 PDARVDEYIKPYEANWFWSIVLKDWKRYIDIMFASLIANILALATIIFSMQVYDRVVPSQ 191
A + + ++ WF V+K K +I+ + S+ I AL T +F V D+V+ +
Sbjct 127 SRASIVGNLAKFDFTWFIPAVIKYRKIFIETLIVSIFLQIFALITPLFFQVVMDKVLVHR 186
Query 192 SIPTLWVLAGGVFIAAIFEFVLRVSRIYLSDIIGKRADLKISDRVFGHALRIK-NKERSK 250
TL V+ + I +FE +L R Y+ R D+++ R+F H L + + ++
Sbjct 187 GFSTLNVITVALAIVVLFEIILGGLRTYVFAHSTSRIDVELGARLFRHLLALPISYFEAR 246
Query 251 STGTFISQIRELEGVRELVTSTTITAIADLPFFLLFLVILWIIGGHVFWVVVIMVPLMIL 310
G ++++REL+ +R +T +T+I DL F +F ++W + VV+ +P ++
Sbjct 247 RVGDTVARVRELDQIRNFLTGQALTSILDLLFSFIFFAVMWYYSPKLTLVVLGSLPCYVI 306
Query 311 PGILAQKKLAKLAQEGMRESAIRNAILVEAVQGIEDIKLLRAESRFQNQWNHMNELSADY 370
+ L + + +A + LVE+V I IK + + N W+ A Y
Sbjct 307 WSVFISPILRRRLDDKFARNADNQSFLVESVTAINTIKAMAISPQMTNIWDKQ---LASY 363
Query 371 SMQQRKIVGVLSAWTQKLQGLTYALVVL---VGCFAVMDGEMTTGALVACSILSSRMLGP 427
K+ + + Q +Q + A++V+ +G V+ G+++ G L+A ++L+ +++ P
Sbjct 364 VAVSFKVTVLATIGQQGIQLIQKAVMVINLWLGAHLVISGDLSIGQLIAFNMLAGQIISP 423
Query 428 ISQITGVLGRLQQAKVAKQSLDELMKKPVDQPDRAHLVHKPVIHGDYDLSNVVFQYNPED 487
+ ++ + QQ ++ L +++ P + + V P I G+ N+ F+Y P D
Sbjct 424 VIRLAQIWQDFQQVGISVTRLGDVLNSPTENNTAS--VSLPEIQGEISFRNIKFRYKP-D 480
Query 488 SKPNLAIQKLRIKAGEKIAILGRNGAGKSTLLQLLSGMQSPINGKLTLDDLELSLIDPAD 547
S L L I GE I I+GR+G+GKSTL +L+ P G++ +D +L+L DP
Sbjct 481 SPMILNNINLDISQGEVIGIVGRSGSGKSTLTKLIQRFYIPEQGQVLIDGHDLALADPNW 540
Query 548 IRRDMGLLNQNASLFYGTIRENLTLGAPLANDHEIIKALKVTGALSFVEEKKEGLDHIIL 607
+RR +G++ Q+ L +IREN+ L P ++I A K+ GA F+ E +EG + ++
Sbjct 541 LRRQVGVVLQDNVLLNRSIRENIALTNPGMPMEKVIAAAKLAGAHDFISELREGYNTVVG 600
Query 608 EGGVGFSGGQRQALLLARLLIRQPNILLLDEPTAAIDDVSEKQLIDHLKQWLAHRTLVVA 667
E G G SGGQRQ + +AR L+ P IL+ DE T+A+D SE ++ ++ + +RT+++
Sbjct 601 EQGAGLSGGQRQRIAIARALVNNPRILIFDEATSALDYESENIIMHNMHKICQNRTVLII 660
Query 668 THRRAVLELVDRIIVINDGKIVMDGPRDQILK 699
HR + ++ DRIIV++ G+I+ G ++LK
Sbjct 661 AHRLSTVKNADRIIVMDKGEIIEQGKHQELLK 692
>Q93FH2 Leukotoxin translocation ATP-binding protein LktB [Mannheimia
haemolytica]
Length=708
Score = 291 bits (744), Expect = 5e-91
Identities = 191/691 (28%), Positives = 343/691 (50%), Gaps = 8/691 (1%)
Query 12 LQAVLTIARHYRIESSEERIRLQLDWNQNQNPEEVLELMCRQVGLSLRVAKFNSDLLNPW 71
L A+ +A+++ I + E I+ + D + L + + L + K L+
Sbjct 12 LVALTMLAQYHNISLNPEEIKHKFDLDGKGLSLTSWLLAAKSLALKAKHIKKEISRLHLV 71
Query 72 RLPVIAEFKDGQIGVVDKADTEGNVSIQLSGDHGLSQSFAIDSLKGLIKHIYIMRPESSI 131
LP + +G+ ++ K DT+ N + + + Q + D + + I+
Sbjct 72 NLPALVWQDNGKHFLLVKVDTDNNRYLTYNLEQDAPQILSQDEFEACYQGQLILVTSR-- 129
Query 132 PDARVDEYIKPYEANWFWSIVLKDWKRYIDIMFASLIANILALATIIFSMQVYDRVVPSQ 191
A V + ++ WF V+K K +++ + S+ I AL T +F V D+V+ +
Sbjct 130 --ASVVGQLAKFDFTWFIPAVIKYRKIFLETLIVSIFLQIFALITPLFFQVVMDKVLVHR 187
Query 192 SIPTLWVLAGGVFIAAIFEFVLRVSRIYLSDIIGKRADLKISDRVFGHALRIK-NKERSK 250
TL ++ + I IFE VL R Y+ R D+++ ++F H L + + ++
Sbjct 188 GFSTLNIITVALAIVIIFEIVLSGLRTYVFSHSTSRIDVELGAKLFRHLLSLPISYFENR 247
Query 251 STGTFISQIRELEGVRELVTSTTITAIADLPFFLLFLVILWIIGGHVFWVVVIMVPLMIL 310
G ++++REL+ +R +T +T++ DL F +F ++W + V++ +P IL
Sbjct 248 RVGDTVARVRELDQIRNFLTGQALTSVLDLLFSFIFFAVMWYYSPKLTLVILGSLPCYIL 307
Query 311 PGILAQKKLAKLAQEGMRESAIRNAILVEAVQGIEDIKLLRAESRFQNQWNHMNELSADY 370
I L + E SA A LVE+V I IK + + + W+
Sbjct 308 WSIFISPILRRRLDEKFARSADNQAFLVESVTAINMIKAMAVAPQMTDTWDKQLASYVSS 367
Query 371 SMQQRKIVGVLSAWTQKLQGLTYALVVLVGCFAVMDGEMTTGALVACSILSSRMLGPISQ 430
S + + + Q +Q + + +G V+ G+++ G L+A ++LS +++ P+ +
Sbjct 368 SFRVTVLATIGQQGVQLIQKTVMVINLWLGAHLVISGDLSIGQLIAFNMLSGQVIAPVIR 427
Query 431 ITGVLGRLQQAKVAKQSLDELMKKPVDQPDRAHLVHKPVIHGDYDLSNVVFQYNPEDSKP 490
+ + QQ ++ L +++ P +Q + P I GD N+ F+Y P D+
Sbjct 428 LAQLWQDFQQVGISVTRLGDVLNSPTEQYQGK--LSLPEIKGDISFKNIRFRYKP-DAPT 484
Query 491 NLAIQKLRIKAGEKIAILGRNGAGKSTLLQLLSGMQSPINGKLTLDDLELSLIDPADIRR 550
L L I+ GE I I+GR+G+GKSTL +LL P NG++ +D +L+L DP +RR
Sbjct 485 ILNNVNLEIRQGEVIGIVGRSGSGKSTLTKLLQRFYIPENGQVLIDGHDLALADPNWLRR 544
Query 551 DMGLLNQNASLFYGTIRENLTLGAPLANDHEIIKALKVTGALSFVEEKKEGLDHIILEGG 610
+G++ Q+ L +IREN+ L P +I A K+ GA F+ E +EG + I+ E G
Sbjct 545 QIGVVLQDNVLLNRSIRENIALSDPGMPMERVIYAAKLAGAHDFISELREGYNTIVGEQG 604
Query 611 VGFSGGQRQALLLARLLIRQPNILLLDEPTAAIDDVSEKQLIDHLKQWLAHRTLVVATHR 670
G SGGQRQ + +AR L+ P IL+ DE T+A+D SE ++ ++++ RT+++ HR
Sbjct 605 AGLSGGQRQRIAIARALVNNPKILIFDEATSALDYESEHIIMQNMQKICQGRTVILIAHR 664
Query 671 RAVLELVDRIIVINDGKIVMDGPRDQILKQS 701
+ ++ DRIIV+ G+IV G ++L+ S
Sbjct 665 LSTVKNADRIIVMEKGEIVEQGKHHELLQNS 695
>Q933E0 Leukotoxin translocation ATP-binding protein LktB [Bibersteinia
trehalosi]
Length=708
Score = 290 bits (742), Expect = 9e-91
Identities = 190/691 (27%), Positives = 343/691 (50%), Gaps = 8/691 (1%)
Query 12 LQAVLTIARHYRIESSEERIRLQLDWNQNQNPEEVLELMCRQVGLSLRVAKFNSDLLNPW 71
L A+ +A+++ I + E I+ + D + L + + L + K L+
Sbjct 12 LVALTMLAQYHNISLNPEEIKHKFDLDGKGLSLTSWLLAAKSLALKAKHIKKEISRLHLV 71
Query 72 RLPVIAEFKDGQIGVVDKADTEGNVSIQLSGDHGLSQSFAIDSLKGLIKHIYIMRPESSI 131
LP + +G+ ++ K DT+ N + + + Q + D + + I+
Sbjct 72 NLPALVWQDNGKHFLLVKVDTDNNRYLTYNLEQDAPQILSQDEFEACYQGQLILVTSR-- 129
Query 132 PDARVDEYIKPYEANWFWSIVLKDWKRYIDIMFASLIANILALATIIFSMQVYDRVVPSQ 191
A V + ++ WF V+K K +++ + S+ I AL T +F V D+V+ +
Sbjct 130 --ASVVGQLAKFDFTWFIPAVIKYRKIFLETLIVSIFLQIFALITPLFFQVVMDKVLVHR 187
Query 192 SIPTLWVLAGGVFIAAIFEFVLRVSRIYLSDIIGKRADLKISDRVFGHALRIK-NKERSK 250
TL ++ + I IFE VL R Y+ R D+++ ++F H L + + ++
Sbjct 188 GFSTLNIITVALAIVIIFEIVLSGLRTYVFSHSTSRIDVELGAKLFRHLLSLPISYFENR 247
Query 251 STGTFISQIRELEGVRELVTSTTITAIADLPFFLLFLVILWIIGGHVFWVVVIMVPLMIL 310
G ++++REL+ +R +T +T++ DL F +F ++W + V++ +P IL
Sbjct 248 RVGDTVARVRELDQIRNFLTGQALTSVLDLLFSFIFFAVMWYYSPKLTLVILGSLPFYIL 307
Query 311 PGILAQKKLAKLAQEGMRESAIRNAILVEAVQGIEDIKLLRAESRFQNQWNHMNELSADY 370
I L + + SA A LVE+V I IK + + + W+
Sbjct 308 WSIFISPILRRRLDDKFARSADNQAFLVESVTAINMIKAMAVAPQMTDTWDKQLASYVSS 367
Query 371 SMQQRKIVGVLSAWTQKLQGLTYALVVLVGCFAVMDGEMTTGALVACSILSSRMLGPISQ 430
S + + + Q +Q + + +G V+ G+++ G L+A ++LS +++ P+ +
Sbjct 368 SFRVTVLATIGQQGVQLIQKTVMVINLWLGAHLVISGDLSIGQLIAFNMLSGQVIAPVIR 427
Query 431 ITGVLGRLQQAKVAKQSLDELMKKPVDQPDRAHLVHKPVIHGDYDLSNVVFQYNPEDSKP 490
+ + QQ ++ L +++ P +Q + P I GD N+ F+Y P D+
Sbjct 428 LAQLWQDFQQVGISVTRLGDVLNSPTEQYQGK--LSLPEIKGDISFKNIRFRYKP-DAPT 484
Query 491 NLAIQKLRIKAGEKIAILGRNGAGKSTLLQLLSGMQSPINGKLTLDDLELSLIDPADIRR 550
L L I+ GE I I+GR+G+GKSTL +LL P NG++ +D +L+L DP +RR
Sbjct 485 ILNNVNLEIRQGEVIGIVGRSGSGKSTLTKLLQRFYIPENGQVLIDGHDLALADPNWLRR 544
Query 551 DMGLLNQNASLFYGTIRENLTLGAPLANDHEIIKALKVTGALSFVEEKKEGLDHIILEGG 610
+G++ Q+ L +IREN+ L P +I A K+ GA F+ E +EG + I+ E G
Sbjct 545 QIGVVLQDNVLLNRSIRENIALSDPGMPMERVIYAAKLAGAHDFISELREGYNTIVGEQG 604
Query 611 VGFSGGQRQALLLARLLIRQPNILLLDEPTAAIDDVSEKQLIDHLKQWLAHRTLVVATHR 670
G SGGQRQ + +AR L+ P IL+ DE T+A+D SE ++ ++++ RT+++ HR
Sbjct 605 AGLSGGQRQRIAIARALVNNPKILIFDEATSALDYESEHIIMQNMQKICQGRTVILIAHR 664
Query 671 RAVLELVDRIIVINDGKIVMDGPRDQILKQS 701
+ ++ DRIIV+ G+IV G ++L+ S
Sbjct 665 LSTVKNADRIIVMEKGEIVEQGKHHELLQNS 695
>P0C086 Leukotoxin translocation ATP-binding protein LktB [Mannheimia
haemolytica]
Length=708
Score = 290 bits (741), Expect = 1e-90
Identities = 190/691 (27%), Positives = 343/691 (50%), Gaps = 8/691 (1%)
Query 12 LQAVLTIARHYRIESSEERIRLQLDWNQNQNPEEVLELMCRQVGLSLRVAKFNSDLLNPW 71
L A+ +A+++ I + E I+ + D + L + + L + K L+
Sbjct 12 LVALTMLAQYHNISLNPEEIKHKFDLDGKGLSLTSWLLAAKSLALKAKHIKKEISRLHLV 71
Query 72 RLPVIAEFKDGQIGVVDKADTEGNVSIQLSGDHGLSQSFAIDSLKGLIKHIYIMRPESSI 131
LP + +G+ ++ K DT+ N + + + Q + D + + I+
Sbjct 72 NLPALVWQDNGKHFLLVKVDTDNNRYLTYNLEQDAPQILSQDEFEACYQGQLILVTSR-- 129
Query 132 PDARVDEYIKPYEANWFWSIVLKDWKRYIDIMFASLIANILALATIIFSMQVYDRVVPSQ 191
A V + ++ WF V+K K +++ + S+ I AL T +F V D+V+ +
Sbjct 130 --ASVVGQLAKFDFTWFIPAVIKYRKIFLETLIVSIFLQIFALITPLFFQVVMDKVLVHR 187
Query 192 SIPTLWVLAGGVFIAAIFEFVLRVSRIYLSDIIGKRADLKISDRVFGHALRIK-NKERSK 250
TL ++ + I IFE VL R Y+ R D+++ ++F H L + + ++
Sbjct 188 GFSTLNIITVALAIVIIFEIVLSGLRTYVFSHSTSRIDVELGAKLFRHLLSLPISYFENR 247
Query 251 STGTFISQIRELEGVRELVTSTTITAIADLPFFLLFLVILWIIGGHVFWVVVIMVPLMIL 310
G ++++REL+ +R +T +T++ DL F +F ++W + V++ +P IL
Sbjct 248 RVGDTVARVRELDQIRNFLTGQALTSVLDLLFSFIFFAVMWYYSPKLTLVILGSLPCYIL 307
Query 311 PGILAQKKLAKLAQEGMRESAIRNAILVEAVQGIEDIKLLRAESRFQNQWNHMNELSADY 370
I L + + SA A LVE+V I IK + + + W+
Sbjct 308 WSIFISPILRRRLDDKFARSADNQAFLVESVTAINMIKAMAVAPQMTDTWDKQLASYVSS 367
Query 371 SMQQRKIVGVLSAWTQKLQGLTYALVVLVGCFAVMDGEMTTGALVACSILSSRMLGPISQ 430
S + + + Q +Q + + +G V+ G+++ G L+A ++LS +++ P+ +
Sbjct 368 SFRVTVLATIGQQGVQLIQKTVMVINLWLGAHLVISGDLSIGQLIAFNMLSGQVIAPVIR 427
Query 431 ITGVLGRLQQAKVAKQSLDELMKKPVDQPDRAHLVHKPVIHGDYDLSNVVFQYNPEDSKP 490
+ + QQ ++ L +++ P +Q + P I GD N+ F+Y P D+
Sbjct 428 LAQLWQDFQQVGISVTRLGDVLNSPTEQYQGK--LSLPEIKGDISFKNIRFRYKP-DAPT 484
Query 491 NLAIQKLRIKAGEKIAILGRNGAGKSTLLQLLSGMQSPINGKLTLDDLELSLIDPADIRR 550
L L I+ GE I I+GR+G+GKSTL +LL P NG++ +D +L+L DP +RR
Sbjct 485 ILNNVNLEIRQGEVIGIVGRSGSGKSTLTKLLQRFYIPENGQVLIDGHDLALADPNWLRR 544
Query 551 DMGLLNQNASLFYGTIRENLTLGAPLANDHEIIKALKVTGALSFVEEKKEGLDHIILEGG 610
+G++ Q+ L +IREN+ L P +I A K+ GA F+ E +EG + I+ E G
Sbjct 545 QIGVVLQDNVLLNRSIRENIALSDPGMPMERVIYAAKLAGAHDFISELREGYNTIVGEQG 604
Query 611 VGFSGGQRQALLLARLLIRQPNILLLDEPTAAIDDVSEKQLIDHLKQWLAHRTLVVATHR 670
G SGGQRQ + +AR L+ P IL+ DE T+A+D SE ++ ++++ RT+++ HR
Sbjct 605 AGLSGGQRQRIAIARALVNNPKILIFDEATSALDYESEHIIMQNMQKICQGRTVILIAHR 664
Query 671 RAVLELVDRIIVINDGKIVMDGPRDQILKQS 701
+ ++ DRIIV+ G+IV G ++L+ S
Sbjct 665 LSTVKNADRIIVMEKGEIVEQGKHHELLQNS 695
>Q93FH0 Leukotoxin translocation ATP-binding protein LktB [Mannheimia
haemolytica]
Length=708
Score = 290 bits (741), Expect = 1e-90
Identities = 190/691 (27%), Positives = 342/691 (49%), Gaps = 8/691 (1%)
Query 12 LQAVLTIARHYRIESSEERIRLQLDWNQNQNPEEVLELMCRQVGLSLRVAKFNSDLLNPW 71
L A+ +A+++ I + E I+ + D + L + + L + K L+
Sbjct 12 LVALTMLAQYHNISLNPEEIKHKFDLDGKGLSLTAWLLAAKSLALKAKHIKKEVSRLHLV 71
Query 72 RLPVIAEFKDGQIGVVDKADTEGNVSIQLSGDHGLSQSFAIDSLKGLIKHIYIMRPESSI 131
LP + +G+ ++ K DT+ N + + Q + D + + I+
Sbjct 72 NLPALVWQDNGKHFLLVKVDTDNNRYLTYDLEKDAPQILSQDEFEACYQGQLILVTSR-- 129
Query 132 PDARVDEYIKPYEANWFWSIVLKDWKRYIDIMFASLIANILALATIIFSMQVYDRVVPSQ 191
A V + ++ WF V+K K +++ + S+ I AL T +F V D+V+ +
Sbjct 130 --ASVVGQLAKFDFTWFIPAVIKYRKIFLETLIVSIFLQIFALITPLFFQVVMDKVLVHR 187
Query 192 SIPTLWVLAGGVFIAAIFEFVLRVSRIYLSDIIGKRADLKISDRVFGHALRIK-NKERSK 250
TL ++ + I IFE VL R Y+ R D+++ ++F H L + + ++
Sbjct 188 GFSTLNIITVALAIVIIFEIVLSGLRTYVFSHSTSRIDVELGAKLFRHLLSLPISYFENR 247
Query 251 STGTFISQIRELEGVRELVTSTTITAIADLPFFLLFLVILWIIGGHVFWVVVIMVPLMIL 310
G ++++REL+ +R +T +T++ DL F +F ++W + V++ +P IL
Sbjct 248 RVGDTVARVRELDQIRNFLTGQALTSVLDLLFSFIFFAVMWYYSPKLTLVILGSLPCYIL 307
Query 311 PGILAQKKLAKLAQEGMRESAIRNAILVEAVQGIEDIKLLRAESRFQNQWNHMNELSADY 370
I L + + SA A LVE+V I IK + + + W+
Sbjct 308 WSIFISPILRRRLDDKFARSADNQAFLVESVTAINMIKAMAVAPQMTDTWDKQLASYVSS 367
Query 371 SMQQRKIVGVLSAWTQKLQGLTYALVVLVGCFAVMDGEMTTGALVACSILSSRMLGPISQ 430
S + + + Q +Q + + +G V+ G+++ G L+A ++LS +++ P+ +
Sbjct 368 SFRVTVLATIGQQGVQLIQKTVMVINLWLGAHLVISGDLSIGQLIAFNMLSGQVIAPVIR 427
Query 431 ITGVLGRLQQAKVAKQSLDELMKKPVDQPDRAHLVHKPVIHGDYDLSNVVFQYNPEDSKP 490
+ + QQ ++ L +++ P +Q + P I GD N+ F+Y P D+
Sbjct 428 LAQLWQDFQQVGISVTRLGDVLNSPTEQYQGK--LSLPEIKGDISFKNIRFRYKP-DAPT 484
Query 491 NLAIQKLRIKAGEKIAILGRNGAGKSTLLQLLSGMQSPINGKLTLDDLELSLIDPADIRR 550
L L I+ GE I I+GR+G+GKSTL +LL P NG++ +D +L+L DP +RR
Sbjct 485 ILNNVNLEIRQGEVIGIVGRSGSGKSTLTKLLQRFYIPENGQVLIDGHDLALADPNWLRR 544
Query 551 DMGLLNQNASLFYGTIRENLTLGAPLANDHEIIKALKVTGALSFVEEKKEGLDHIILEGG 610
+G++ Q+ L +IREN+ L P +I A K+ GA F+ E +EG + I+ E G
Sbjct 545 QIGVVLQDNVLLNRSIRENIALSDPGMPMERVIYAAKLAGAHDFISELREGYNTIVGEQG 604
Query 611 VGFSGGQRQALLLARLLIRQPNILLLDEPTAAIDDVSEKQLIDHLKQWLAHRTLVVATHR 670
G SGGQRQ + +AR L+ P IL+ DE T+A+D SE ++ ++++ RT+++ HR
Sbjct 605 AGLSGGQRQRIAIARALVNNPKILIFDEATSALDYESEHIIMQNMQKICQGRTVILIAHR 664
Query 671 RAVLELVDRIIVINDGKIVMDGPRDQILKQS 701
+ ++ DRIIV+ G+IV G ++L+ S
Sbjct 665 LSTVKNADRIIVMEKGEIVEQGKHHELLQNS 695
>Q93FH3 Leukotoxin translocation ATP-binding protein LktB [Mannheimia
haemolytica]
Length=708
Score = 290 bits (741), Expect = 1e-90
Identities = 190/691 (27%), Positives = 343/691 (50%), Gaps = 8/691 (1%)
Query 12 LQAVLTIARHYRIESSEERIRLQLDWNQNQNPEEVLELMCRQVGLSLRVAKFNSDLLNPW 71
L A+ +A+++ I + E I+ + D + L + + L + K L+
Sbjct 12 LVALTMLAQYHNISLNPEEIKHKFDLDGKGLSLTSWLLAAKSLALKAKHIKKEISRLHLV 71
Query 72 RLPVIAEFKDGQIGVVDKADTEGNVSIQLSGDHGLSQSFAIDSLKGLIKHIYIMRPESSI 131
LP + +G+ ++ K DT+ N + + + Q + D + + I+
Sbjct 72 NLPALVWQDNGKHFLLVKVDTDNNRYLTYNLEQDAPQILSQDEFEACYQGQLILVTSR-- 129
Query 132 PDARVDEYIKPYEANWFWSIVLKDWKRYIDIMFASLIANILALATIIFSMQVYDRVVPSQ 191
A V + ++ WF V+K K +++ + S+ I AL T +F V D+V+ +
Sbjct 130 --ASVVGQLAKFDFTWFIPAVIKYRKIFLETLIVSIFLQIFALITPLFFQVVMDKVLVHR 187
Query 192 SIPTLWVLAGGVFIAAIFEFVLRVSRIYLSDIIGKRADLKISDRVFGHALRIK-NKERSK 250
TL ++ + I IFE VL R Y+ R D+++ ++F H L + + ++
Sbjct 188 GFSTLNIITVALAIVIIFEIVLSGLRTYVFSHSTSRIDVELGAKLFRHLLSLPISYFENR 247
Query 251 STGTFISQIRELEGVRELVTSTTITAIADLPFFLLFLVILWIIGGHVFWVVVIMVPLMIL 310
G ++++REL+ +R +T +T++ DL F +F ++W + V++ +P IL
Sbjct 248 RVGDTVARVRELDQIRNFLTGQALTSVLDLLFSFIFFAVMWYYSPKLTLVILGSLPCYIL 307
Query 311 PGILAQKKLAKLAQEGMRESAIRNAILVEAVQGIEDIKLLRAESRFQNQWNHMNELSADY 370
I L + + SA A LVE+V I IK + + + W+
Sbjct 308 WSIFISPILRRRLDDKFARSADNQAFLVESVTAINMIKAMAVAPQMTDTWDKQLASYVSS 367
Query 371 SMQQRKIVGVLSAWTQKLQGLTYALVVLVGCFAVMDGEMTTGALVACSILSSRMLGPISQ 430
S + + + Q +Q + + +G V+ G+++ G L+A ++LS +++ P+ +
Sbjct 368 SFRVTVLATIGQQGVQLIQKTVMVINLWLGAHLVISGDLSIGQLIAFNMLSGQVIAPVIR 427
Query 431 ITGVLGRLQQAKVAKQSLDELMKKPVDQPDRAHLVHKPVIHGDYDLSNVVFQYNPEDSKP 490
+ + QQ ++ L +++ P +Q + P I GD N+ F+Y P D+
Sbjct 428 LAQLWQDFQQVGISVTRLGDVLNSPTEQYQGK--LSLPEIKGDISFKNIRFRYKP-DAPT 484
Query 491 NLAIQKLRIKAGEKIAILGRNGAGKSTLLQLLSGMQSPINGKLTLDDLELSLIDPADIRR 550
L L I+ GE I I+GR+G+GKSTL +LL P NG++ +D +L+L DP +RR
Sbjct 485 ILNNVNLEIRQGEVIGIVGRSGSGKSTLTKLLQRFYIPENGQVLIDGHDLALADPNWLRR 544
Query 551 DMGLLNQNASLFYGTIRENLTLGAPLANDHEIIKALKVTGALSFVEEKKEGLDHIILEGG 610
+G++ Q+ L +IREN+ L P +I A K+ GA F+ E +EG + I+ E G
Sbjct 545 QIGVVLQDNVLLNRSIRENIALSDPGMPMERVIYAAKLAGAHDFISELREGYNTIVGEQG 604
Query 611 VGFSGGQRQALLLARLLIRQPNILLLDEPTAAIDDVSEKQLIDHLKQWLAHRTLVVATHR 670
G SGGQRQ + +AR L+ P IL+ DE T+A+D SE ++ ++++ RT+++ HR
Sbjct 605 AGLSGGQRQRIAIARALVNNPKILIFDEATSALDYQSEHIIMQNMQKICQGRTVILIAHR 664
Query 671 RAVLELVDRIIVINDGKIVMDGPRDQILKQS 701
+ ++ DRIIV+ G+IV G ++L+ S
Sbjct 665 LSTVKNADRIIVMEKGEIVEQGKHHELLQNS 695
>P0C087 Leukotoxin translocation ATP-binding protein LktB [Mannheimia
haemolytica]
Length=708
Score = 290 bits (741), Expect = 1e-90
Identities = 190/691 (27%), Positives = 343/691 (50%), Gaps = 8/691 (1%)
Query 12 LQAVLTIARHYRIESSEERIRLQLDWNQNQNPEEVLELMCRQVGLSLRVAKFNSDLLNPW 71
L A+ +A+++ I + E I+ + D + L + + L + K L+
Sbjct 12 LVALTMLAQYHNISLNPEEIKHKFDLDGKGLSLTSWLLAAKSLALKAKHIKKEISRLHLV 71
Query 72 RLPVIAEFKDGQIGVVDKADTEGNVSIQLSGDHGLSQSFAIDSLKGLIKHIYIMRPESSI 131
LP + +G+ ++ K DT+ N + + + Q + D + + I+
Sbjct 72 NLPALVWQDNGKHFLLVKVDTDNNRYLTYNLEQDAPQILSQDEFEACYQGQLILVTSR-- 129
Query 132 PDARVDEYIKPYEANWFWSIVLKDWKRYIDIMFASLIANILALATIIFSMQVYDRVVPSQ 191
A V + ++ WF V+K K +++ + S+ I AL T +F V D+V+ +
Sbjct 130 --ASVVGQLAKFDFTWFIPAVIKYRKIFLETLIVSIFLQIFALITPLFFQVVMDKVLVHR 187
Query 192 SIPTLWVLAGGVFIAAIFEFVLRVSRIYLSDIIGKRADLKISDRVFGHALRIK-NKERSK 250
TL ++ + I IFE VL R Y+ R D+++ ++F H L + + ++
Sbjct 188 GFSTLNIITVALAIVIIFEIVLSGLRTYVFSHSTSRIDVELGAKLFRHLLSLPISYFENR 247
Query 251 STGTFISQIRELEGVRELVTSTTITAIADLPFFLLFLVILWIIGGHVFWVVVIMVPLMIL 310
G ++++REL+ +R +T +T++ DL F +F ++W + V++ +P IL
Sbjct 248 RVGDTVARVRELDQIRNFLTGQALTSVLDLLFSFIFFAVMWYYSPKLTLVILGSLPCYIL 307
Query 311 PGILAQKKLAKLAQEGMRESAIRNAILVEAVQGIEDIKLLRAESRFQNQWNHMNELSADY 370
I L + + SA A LVE+V I IK + + + W+
Sbjct 308 WSIFISPILRRRLDDKFARSADNQAFLVESVTAINMIKAMAVAPQMTDTWDKQLASYVSS 367
Query 371 SMQQRKIVGVLSAWTQKLQGLTYALVVLVGCFAVMDGEMTTGALVACSILSSRMLGPISQ 430
S + + + Q +Q + + +G V+ G+++ G L+A ++LS +++ P+ +
Sbjct 368 SFRVTVLATIGQQGVQLIQKTVMVINLWLGAHLVISGDLSIGQLIAFNMLSGQVIAPVIR 427
Query 431 ITGVLGRLQQAKVAKQSLDELMKKPVDQPDRAHLVHKPVIHGDYDLSNVVFQYNPEDSKP 490
+ + QQ ++ L +++ P +Q + P I GD N+ F+Y P D+
Sbjct 428 LAQLWQDFQQVGISVTRLGDVLNSPTEQYQGK--LSLPEIKGDISFKNIRFRYKP-DAPT 484
Query 491 NLAIQKLRIKAGEKIAILGRNGAGKSTLLQLLSGMQSPINGKLTLDDLELSLIDPADIRR 550
L L I+ GE I I+GR+G+GKSTL +LL P NG++ +D +L+L DP +RR
Sbjct 485 ILNNVNLEIRQGEVIGIVGRSGSGKSTLTKLLQRFYIPENGQVLIDGHDLALADPNWLRR 544
Query 551 DMGLLNQNASLFYGTIRENLTLGAPLANDHEIIKALKVTGALSFVEEKKEGLDHIILEGG 610
+G++ Q+ L +IREN+ L P +I A K+ GA F+ E +EG + I+ E G
Sbjct 545 QIGVVLQDNVLLNRSIRENIALSDPGMPMERVIYAAKLAGAHDFISELREGYNTIVGEQG 604
Query 611 VGFSGGQRQALLLARLLIRQPNILLLDEPTAAIDDVSEKQLIDHLKQWLAHRTLVVATHR 670
G SGGQRQ + +AR L+ P IL+ DE T+A+D SE ++ ++++ RT+++ HR
Sbjct 605 AGLSGGQRQRIAIARALVNNPKILIFDEATSALDYESEHIIMQNMQKICQGRTVILIAHR 664
Query 671 RAVLELVDRIIVINDGKIVMDGPRDQILKQS 701
+ ++ DRIIV+ G+IV G ++L+ S
Sbjct 665 LSTVKNADRIIVMEKGEIVEQGKHHELLQNS 695
>Q93FG6 Leukotoxin translocation ATP-binding protein LktB [Mannheimia
haemolytica]
Length=708
Score = 286 bits (732), Expect = 3e-89
Identities = 189/691 (27%), Positives = 342/691 (49%), Gaps = 8/691 (1%)
Query 12 LQAVLTIARHYRIESSEERIRLQLDWNQNQNPEEVLELMCRQVGLSLRVAKFNSDLLNPW 71
L A+ +A+++ I + E I+ + D + L + + L + K L+
Sbjct 12 LVALTMLAQYHNISLNPEEIKHKFDLDGKGLSLTSWLLAAKSLALKAKHIKKEISRLHLV 71
Query 72 RLPVIAEFKDGQIGVVDKADTEGNVSIQLSGDHGLSQSFAIDSLKGLIKHIYIMRPESSI 131
LP + +G+ ++ K DT+ N + + + Q + D + + I+
Sbjct 72 NLPALVWQDNGKHFLLVKVDTDNNRYLTYNLEQDAPQILSQDEFEACYQGQLILVTSR-- 129
Query 132 PDARVDEYIKPYEANWFWSIVLKDWKRYIDIMFASLIANILALATIIFSMQVYDRVVPSQ 191
A V + ++ WF V+K K +++ + S+ I AL T +F V D+V+ +
Sbjct 130 --ASVVGQLAKFDFTWFIPAVIKYRKIFLETLIVSIFLQIFALITPLFFQVVMDKVLVHR 187
Query 192 SIPTLWVLAGGVFIAAIFEFVLRVSRIYLSDIIGKRADLKISDRVFGHALRIK-NKERSK 250
TL ++ + I IFE VL R Y+ R D+++ ++F H L + + ++
Sbjct 188 GFSTLNIITVALAIVIIFEIVLSGLRTYVFSHSTSRIDVELGAKLFRHLLSLPISYFENR 247
Query 251 STGTFISQIRELEGVRELVTSTTITAIADLPFFLLFLVILWIIGGHVFWVVVIMVPLMIL 310
G ++++REL+ +R +T +T++ DL F +F ++W + V++ +P IL
Sbjct 248 RVGDTVARVRELDQIRNFLTGQALTSVLDLLFSFIFFAVMWYYSPKLTLVILGSLPCYIL 307
Query 311 PGILAQKKLAKLAQEGMRESAIRNAILVEAVQGIEDIKLLRAESRFQNQWNHMNELSADY 370
I L + + SA A LVE+V I IK + + + W+
Sbjct 308 WSIFISPILRRRLDDKFARSADNQAFLVESVTAINMIKAMAVAPQMTDTWDKQLASYVSS 367
Query 371 SMQQRKIVGVLSAWTQKLQGLTYALVVLVGCFAVMDGEMTTGALVACSILSSRMLGPISQ 430
S + + + Q +Q + + +G V+ G+++ G L+A ++LS +++ P+ +
Sbjct 368 SFRVTVLATIGQQGVQLIQKTVMVINLWLGAHLVISGDLSIGQLIAFNMLSGQVIAPVIR 427
Query 431 ITGVLGRLQQAKVAKQSLDELMKKPVDQPDRAHLVHKPVIHGDYDLSNVVFQYNPEDSKP 490
+ + QQ ++ L +++ P +Q + P I G N+ F+Y P D+
Sbjct 428 LAQLWQDFQQVGISVTRLGDVLNSPTEQYQGK--LSLPEIKGYISFKNIRFRYKP-DAPT 484
Query 491 NLAIQKLRIKAGEKIAILGRNGAGKSTLLQLLSGMQSPINGKLTLDDLELSLIDPADIRR 550
L L I+ GE I I+GR+G+GKSTL +LL P NG++ +D +L+L DP +RR
Sbjct 485 ILNNVNLEIRQGEVIGIVGRSGSGKSTLTKLLQRFYIPENGQVLIDGHDLALADPNWLRR 544
Query 551 DMGLLNQNASLFYGTIRENLTLGAPLANDHEIIKALKVTGALSFVEEKKEGLDHIILEGG 610
+G++ Q+ L +IREN+ L P +I A K+ GA F+ E +EG + I+ E G
Sbjct 545 QIGVVLQDNVLLNRSIRENIALSDPGMPMERVIYAAKLAGAHDFISELREGYNTIVGEQG 604
Query 611 VGFSGGQRQALLLARLLIRQPNILLLDEPTAAIDDVSEKQLIDHLKQWLAHRTLVVATHR 670
G SGGQRQ + +AR L+ P IL+ DE T+A+D SE ++ ++++ RT+++ HR
Sbjct 605 AGLSGGQRQRIAIARALVNNPKILIFDEATSALDYESEHIIMQNMQKICQGRTVILIAHR 664
Query 671 RAVLELVDRIIVINDGKIVMDGPRDQILKQS 701
+ ++ DRIIV+ G+IV G ++L+ S
Sbjct 665 LSTVKNADRIIVMEKGEIVEQGKHHELLQNS 695
>Q46717 Alpha-hemolysin translocation ATP-binding protein HlyB
[Escherichia coli O157:H7]
Length=706
Score = 284 bits (727), Expect = 1e-88
Identities = 183/693 (26%), Positives = 356/693 (51%), Gaps = 14/693 (2%)
Query 12 LQAVLTIARHYRIESSEERIRLQLDWNQNQNPEEVLELMCRQVGLSLRVAKFNSDLLNPW 71
L A++ +A+++ I + E IR Q + + L + +GL + + + L+
Sbjct 11 LYALILLAQYHNITVNAETIRHQYNTHTQDFGVTEWLLAAKSIGLKAKYVEKHFSRLSII 70
Query 72 RLPVIAEFKDGQIGVVDKADTEGNVSIQLSGDHGLSQSFAIDSLKGLIKHIYIMRPESSI 131
LP + DG+ ++ + + + + + S +F+ D + L + I+
Sbjct 71 SLPALIWRDDGKHYILSRITKDSSRYLVYDPEQHQSLTFSRDEFEKLYQGKVILVTSR-- 128
Query 132 PDARVDEYIKPYEANWFWSIVLKDWKRYIDIMFASLIANILALATIIFSMQVYDRVVPSQ 191
A V + ++ +WF V+K + ++++ S LAL T +F V D+V+ +
Sbjct 129 --ATVVGELAKFDFSWFIPSVVKYRRILLEVLTVSAFIQFLALITPLFFQVVMDKVLVHR 186
Query 192 SIPTLWVLAGGVFIAAIFEFVLRVSRIYLSDIIGKRADLKISDRVFGHALRIK-NKERSK 250
TL ++ I +FE +L +R Y+ R D+++ ++F H L + + ++
Sbjct 187 GFSTLNIITIAFIIVILFEVILTGARTYIFSHTTSRIDVELGAKLFRHLLALPVSYFENR 246
Query 251 STGTFISQIRELEGVRELVTSTTITAIADLPFFLLFLVILWIIGGHVFWVVVIMVPLMIL 310
G ++++RELE +R +T +T++ DL F ++F ++W + V+++ +P ++
Sbjct 247 RVGETVARVRELEQIRNFLTGQALTSVLDLFFSVIFFCVMWYYSPQLTLVILLSLPCYVI 306
Query 311 PGILAQKKLAKLAQEGMRESAIRNAILVEAVQGIEDIKLLRAESRFQNQWNHMNELSADY 370
+ L + + +A A LVE V I IK + + W+ A Y
Sbjct 307 WSLFISPLLRRRLDDKFLRNAENQAFLVETVTAINTIKSMAVSPQMIATWDKQ---LAGY 363
Query 371 SMQQRKIVGVLSAWTQKLQGLTYALVVL---VGCFAVMDGEMTTGALVACSILSSRMLGP 427
++ V Q +Q + +++V+ +G V+ GE++ G L+A ++L+ +++ P
Sbjct 364 VASSFRVNLVAMTGQQGIQLIQKSVMVISLWMGAHLVISGEISIGQLIAFNMLAGQVIAP 423
Query 428 ISQITGVLGRLQQAKVAKQSLDELMKKPVDQPDRAHLVHKPVIHGDYDLSNVVFQYNPED 487
+ ++ + QQ ++ + L +++ PV++ +++ P I GD + NV F+Y+ D
Sbjct 424 VIRLAHLWQDFQQVGISVERLGDVLNTPVEKKSGRNIL--PEIQGDIEFKNVRFRYS-SD 480
Query 488 SKPNLAIQKLRIKAGEKIAILGRNGAGKSTLLQLLSGMQSPINGKLTLDDLELSLIDPAD 547
L L I G+ I I+GR+G+GKSTL +LL P G++ +D +LSL DP
Sbjct 481 GNVILNNINLYISKGDVIGIVGRSGSGKSTLTKLLQRFYIPETGQILIDGHDLSLADPEW 540
Query 548 IRRDMGLLNQNASLFYGTIRENLTLGAPLANDHEIIKALKVTGALSFVEEKKEGLDHIIL 607
+RR +G++ Q L +I +N+TL +P + + I+A ++ GA F+ E KEG + I+
Sbjct 541 LRRQIGVVLQENILLNRSIIDNITLASPAVSMEQAIEAARLAGAHDFIRELKEGYNTIVG 600
Query 608 EGGVGFSGGQRQALLLARLLIRQPNILLLDEPTAAIDDVSEKQLIDHLKQWLAHRTLVVA 667
E GVG SGGQRQ + +AR L+ P IL+ DE T+A+D SE ++ ++ + +RT+++
Sbjct 601 EQGVGLSGGQRQRIAIARALVTNPRILIFDEATSALDYESENIIMKNMSRICKNRTVIII 660
Query 668 THRRAVLELVDRIIVINDGKIVMDGPRDQILKQ 700
HR + ++ +RIIV+++G I DG +++ +
Sbjct 661 AHRLSTVKNANRIIVMDNGFISEDGTHKELISK 693
>Q04473 Toxin RTX-III translocation ATP-binding protein [Actinobacillus
pleuropneumoniae]
Length=711
Score = 283 bits (724), Expect = 4e-88
Identities = 185/691 (27%), Positives = 348/691 (50%), Gaps = 12/691 (2%)
Query 12 LQAVLTIARHYRIESSEERIRLQLDWNQNQNPEEVLELMCRQVGLSLRVAKFNSDLLNPW 71
L A++ +A+++ + + E ++ + D + L + + L ++ K + + L
Sbjct 15 LHALVILAQYHNVAVNPEEVKHKFDLDGKGLDLVAWLLAAKSLELKMKRVKKSIERLPFI 74
Query 72 RLPVIAEFKDGQIGVVDKADTEGNVSIQLSGDHGLSQSFAIDSLKGLIKHIYIMRPESSI 131
LP + DGQ ++ K DT+ N + + + + + + I+
Sbjct 75 HLPALIWRDDGQHVILMKIDTQTNRYLIFDLEERNPKVLSAAEFHEIFQGGMILITSR-- 132
Query 132 PDARVDEYIKPYEANWFWSIVLKDWKRYIDIMFASLIANILALATIIFSMQVYDRVVPSQ 191
A + + ++ WF V+K K +++ + S+ + AL T +F V D+V+ +
Sbjct 133 --ASIMGQLAKFDFTWFIPAVIKYRKIFVETIIVSIFLQLFALITPLFFQVVMDKVLVHR 190
Query 192 SIPTLWVLAGGVFIAAIFEFVLRVSRIYLSDIIGKRADLKISDRVFGHALRIK-NKERSK 250
TL V+ + + IFE VL R Y+ R D+++ ++F H L + + ++
Sbjct 191 GFSTLNVITVALSVVVIFEIVLSGLRTYIFSHSTSRIDVELGAKLFRHLLALPISYFENR 250
Query 251 STGTFISQIRELEGVRELVTSTTITAIADLPFFLLFLVILWIIGGHVFWVVVIMVPLMIL 310
G ++++REL+ +R +T +T++ DL F +F ++W + V+++ +P I
Sbjct 251 RVGDTVARVRELDQIRNFLTGQALTSVLDLLFSFIFFAVMWYYSPKLTIVILLSLPCYIA 310
Query 311 PGILAQKKLAKLAQEGMRESAIRNAILVEAVQGIEDIKLLRAESRFQNQWNHM--NELSA 368
I L + E +A + LVE+V I+ IK L + N W+ + +SA
Sbjct 311 WSIFISPILRRRLDEKFARNADNQSFLVESVSAIDTIKALAVTPQMTNIWDKQLASYVSA 370
Query 369 DYSMQQRKIVGVLSAWTQKLQGLTYALVVLVGCFAVMDGEMTTGALVACSILSSRMLGPI 428
D+ + +G Q +Q + + +G V+ G+++ G L+ ++LS +++ P+
Sbjct 371 DFRVTVLATIG--QQGVQLIQKTVMIINLWLGAHLVISGDLSIGQLITFNMLSGQVIAPV 428
Query 429 SQITGVLGRLQQAKVAKQSLDELMKKPVDQPDRAHLVHKPVIHGDYDLSNVVFQYNPEDS 488
++ + QQ ++ L +++ P + + P I GD ++ F+Y P D+
Sbjct 429 VRLAQLWQDFQQVGISITRLGDVLNSPTENYQGK--LSLPEIFGDIAFKHIRFRYKP-DA 485
Query 489 KPNLAIQKLRIKAGEKIAILGRNGAGKSTLLQLLSGMQSPINGKLTLDDLELSLIDPADI 548
L L +K GE I I+GR+G+GKSTL +LL P NG++ +D +L+L DP +
Sbjct 486 PIILDDVNLSVKQGEVIGIVGRSGSGKSTLTKLLQRFYIPENGQVLIDGHDLALADPNWL 545
Query 549 RRDMGLLNQNASLFYGTIRENLTLGAPLANDHEIIKALKVTGALSFVEEKKEGLDHIILE 608
RR +G++ Q+ L +IR+N+ L P + +I A K+ GA F+ E +EG + I+ E
Sbjct 546 RRQIGVVLQDNVLLNRSIRDNIALTDPSMSMERVIYAAKLAGAHDFISELREGYNTIVGE 605
Query 609 GGVGFSGGQRQALLLARLLIRQPNILLLDEPTAAIDDVSEKQLIDHLKQWLAHRTLVVAT 668
G G SGGQRQ + +AR L+ P IL+ DE T+A+D SE ++ ++++ RT+++
Sbjct 606 LGAGLSGGQRQRIAIARALVNNPRILIFDEATSALDYESEHIIMQNMQKICHGRTVIIIA 665
Query 669 HRRAVLELVDRIIVINDGKIVMDGPRDQILK 699
HR + ++ DRIIV+ G IV G +Q+L+
Sbjct 666 HRLSTVKNADRIIVMEKGHIVEQGKHNQLLE 696
>Q47258 Alpha-hemolysin translocation ATP-binding protein HlyB
[Escherichia coli]
Length=707
Score = 281 bits (718), Expect = 3e-87
Identities = 183/694 (26%), Positives = 348/694 (50%), Gaps = 16/694 (2%)
Query 12 LQAVLTIARHYRIESSEERIRLQLDWNQNQNPEEVLELMCRQVGLSLRVAKFNSDLLNPW 71
L A+ +A+++ + + E I+ + D + L + + L ++ K D LN
Sbjct 11 LYALEILAQYHNVSVNPEEIKHRFDTDGTGLGLTSWLLAAKSLELKVKQVKKTIDRLNFI 70
Query 72 RLPVIAEFKDGQIGVVDKADTEGNVSIQLSGDHGLSQSFAIDSLKGLIK-HIYIMRPESS 130
LP + +DG+ ++ K E N + + + + L + HI ++ SS
Sbjct 71 SLPALVWREDGRHFILTKVSKEANRYLIFDLEQRNPRVLEQSEFEALYQGHIILIASRSS 130
Query 131 IPDARVDEYIKPYEANWFWSIVLKDWKRYIDIMFASLIANILALATIIFSMQVYDRVVPS 190
+ + ++ WF ++K + +I+ + S+ + AL T +F V D+V+
Sbjct 131 VAGK-----LAKFDFTWFIPAIIKYRRIFIETLVVSVFLQLFALITPLFFQVVMDKVLVH 185
Query 191 QSIPTLWVLAGGVFIAAIFEFVLRVSRIYLSDIIGKRADLKISDRVFGHALRIK-NKERS 249
+ TL V+ + + +FE +L R Y+ R D+++ ++F H L + + S
Sbjct 186 RGFSTLNVITVALSVVVVFEIILSGLRTYIFAHSTSRIDVELGAKLFRHLLALPISYFES 245
Query 250 KSTGTFISQIRELEGVRELVTSTTITAIADLPFFLLFLVILWIIGGHVFWVVVIMVPLMI 309
+ G ++++REL+ +R +T +T++ DL F +F ++W + V++ +P
Sbjct 246 RRVGDTVARVRELDQIRNFLTGQALTSVLDLLFSFIFFAVMWYYSPKLTLVILFSLPCYA 305
Query 310 LPGILAQKKLAKLAQEGMRESAIRNAILVEAVQGIEDIKLLRAESRFQNQWNHMNELSAD 369
+ L + + +A + LVE+V I IK + + N W+ A
Sbjct 306 AWSVFISPILRRRLDDKFSRNADNQSFLVESVTAINTIKAMAVSPQMTNIWDKQ---LAG 362
Query 370 YSMQQRKIVGVLSAWTQKLQGLTYALVVL---VGCFAVMDGEMTTGALVACSILSSRMLG 426
Y K+ + + Q +Q + ++++ +G V+ G+++ G L+A ++L+ +++
Sbjct 363 YVAAGFKVTVLATIGQQGIQLIQKTVMIINLWLGAHLVISGDLSIGQLIAFNMLAGQIVA 422
Query 427 PISQITGVLGRLQQAKVAKQSLDELMKKPVDQPDRAHLVHKPVIHGDYDLSNVVFQYNPE 486
P+ ++ + QQ ++ L +++ P + + P I+GD N+ F+Y P
Sbjct 423 PVIRLAQIWQDFQQVGISVTRLGDVLNSPTESYHGKLAL--PEINGDITFRNIRFRYKP- 479
Query 487 DSKPNLAIQKLRIKAGEKIAILGRNGAGKSTLLQLLSGMQSPINGKLTLDDLELSLIDPA 546
DS L L IK GE I I+GR+G+GKSTL +L+ P NG++ +D +L+L DP
Sbjct 480 DSPVILDNINLSIKQGEVIGIVGRSGSGKSTLTKLIQRFYIPENGQVLIDGHDLALADPN 539
Query 547 DIRRDMGLLNQNASLFYGTIRENLTLGAPLANDHEIIKALKVTGALSFVEEKKEGLDHII 606
+RR +G++ Q+ L +I +N++L P + ++I A K+ GA F+ E +EG + I+
Sbjct 540 WLRRQVGVVLQDNVLLNRSIIDNISLANPGMSVEKVIYAAKLAGAHDFISELREGYNTIV 599
Query 607 LEGGVGFSGGQRQALLLARLLIRQPNILLLDEPTAAIDDVSEKQLIDHLKQWLAHRTLVV 666
E G G SGGQRQ + +AR L+ P IL+ DE T+A+D SE ++ ++ + RT+++
Sbjct 600 GEQGAGLSGGQRQRIAIARALVNNPKILIFDEATSALDYESEHIIMRNMHKICKGRTVII 659
Query 667 ATHRRAVLELVDRIIVINDGKIVMDGPRDQILKQ 700
HR + ++ DRIIV+ GKIV G ++L +
Sbjct 660 IAHRLSTVKNADRIIVMEKGKIVEQGKHKELLSE 693
>P10089 Alpha-hemolysin translocation ATP-binding protein HlyB
[Escherichia coli]
Length=707
Score = 281 bits (718), Expect = 3e-87
Identities = 184/694 (27%), Positives = 347/694 (50%), Gaps = 16/694 (2%)
Query 12 LQAVLTIARHYRIESSEERIRLQLDWNQNQNPEEVLELMCRQVGLSLRVAKFNSDLLNPW 71
L A+ +A+++ + + E I+ + D + L + + L ++ K D LN
Sbjct 11 LYALEILAQYHNVSVNPEEIKHRFDTDGTGLGLTSWLLAAKSLELKVKQVKKTIDRLNFI 70
Query 72 RLPVIAEFKDGQIGVVDKADTEGNVSIQLSGDHGLSQSFAIDSLKGLIK-HIYIMRPESS 130
LP + +DG ++ K E N + + + + L + HI ++ SS
Sbjct 71 SLPALVWREDGCHFILTKVSKEANRYLIFDLEQRNPRVLEQSEFEALYQGHIILIASRSS 130
Query 131 IPDARVDEYIKPYEANWFWSIVLKDWKRYIDIMFASLIANILALATIIFSMQVYDRVVPS 190
+ + ++ WF ++K K +I+ + S+ + AL T +F V D+V+
Sbjct 131 VTGK-----LAKFDFTWFIPAIIKYRKIFIETLVVSVFLQLFALITPLFFQVVMDKVLVH 185
Query 191 QSIPTLWVLAGGVFIAAIFEFVLRVSRIYLSDIIGKRADLKISDRVFGHALRIK-NKERS 249
+ TL V+ + + +FE +L R Y+ R D+++ ++F H L + + S
Sbjct 186 RGFSTLNVITVALSVVVVFEIILSGLRTYIFAHSTSRIDVELGAKLFRHLLALPISYFES 245
Query 250 KSTGTFISQIRELEGVRELVTSTTITAIADLPFFLLFLVILWIIGGHVFWVVVIMVPLMI 309
+ G ++++REL+ +R +T +T++ DL F +F ++W + V++ +P
Sbjct 246 RRVGDTVARVRELDQIRNFLTGQALTSVLDLLFSFIFFAVMWYYSPKLTLVILFSLPCYA 305
Query 310 LPGILAQKKLAKLAQEGMRESAIRNAILVEAVQGIEDIKLLRAESRFQNQWNHMNELSAD 369
+ L + + +A + LVE+V I IK + + N W+ A
Sbjct 306 AWSVFISPILRRRLDDKFSRNADNQSFLVESVTAINTIKAMAVSPQMTNIWDKQ---LAG 362
Query 370 YSMQQRKIVGVLSAWTQKLQGLTYALVVL---VGCFAVMDGEMTTGALVACSILSSRMLG 426
Y K+ + + Q +Q + ++++ +G V+ G+++ G L+A ++L+ +++
Sbjct 363 YVAAGFKVTVLATIGQQGIQLIQKTVMIINLWLGAHLVISGDLSIGQLIAFNMLAGQIVA 422
Query 427 PISQITGVLGRLQQAKVAKQSLDELMKKPVDQPDRAHLVHKPVIHGDYDLSNVVFQYNPE 486
P+ ++ + QQ ++ L +++ P + + P I+GD N+ F+Y P
Sbjct 423 PVIRLAQIWQDFQQVGISVTRLGDVLNSPTESYHGKLAL--PEINGDITFRNIRFRYKP- 479
Query 487 DSKPNLAIQKLRIKAGEKIAILGRNGAGKSTLLQLLSGMQSPINGKLTLDDLELSLIDPA 546
DS L L IK GE I I+GR+G+GKSTL +L+ P NG++ +D +L+L DP
Sbjct 480 DSPVILDNINLSIKQGEVIGIVGRSGSGKSTLTKLIQRFYIPENGQVLIDGHDLALADPN 539
Query 547 DIRRDMGLLNQNASLFYGTIRENLTLGAPLANDHEIIKALKVTGALSFVEEKKEGLDHII 606
+RR +G++ Q+ L +I +N++L P + ++I A K+ GA F+ E +EG + I+
Sbjct 540 WLRRQVGVVLQDNVLLNRSIIDNISLANPGMSVEKVIYAAKLAGAHDFISELREGYNTIV 599
Query 607 LEGGVGFSGGQRQALLLARLLIRQPNILLLDEPTAAIDDVSEKQLIDHLKQWLAHRTLVV 666
E G G SGGQRQ + +AR L+ P IL+ DE T+A+D SE ++ ++ + RT+++
Sbjct 600 GEQGAGLSGGQRQRIAIARALVNNPKILIFDEATSALDYESEHVIMRNMHKICKGRTVII 659
Query 667 ATHRRAVLELVDRIIVINDGKIVMDGPRDQILKQ 700
HR + ++ DRIIV+ GKIV G ++L +
Sbjct 660 IAHRLSTVKNADRIIVMEKGKIVEQGKHKELLSE 693
>P0DKX6 Cyclolysin secretion/processing ATP-binding protein CyaB
[Bordetella pertussis (strain ATCC 9797 / DSM 5571 / NCTC
10739 / 18323)]
Length=712
Score = 281 bits (718), Expect = 3e-87
Identities = 183/689 (27%), Positives = 350/689 (51%), Gaps = 12/689 (2%)
Query 12 LQAVLTIARHYRIESSEERIRLQLDWNQNQNPEEVLELMCRQVGLSLRVAKFNSDLLNPW 71
L ++ +AR++ + + E++R + + + E ++L R+VGL +R + L
Sbjct 16 LLCLVMLARYHGLAADPEQLRHE--FAEQAFCSETIQLAARRVGLKVRRHRPAPARLPRA 73
Query 72 RLPVIAEFKDGQIGVVDKADTEGNVSIQLSGDHGLSQSFAIDSLKGLIKHIYIMRPESSI 131
LP IA + G V+ + + + ++ + + L ++ ++
Sbjct 74 PLPAIALDRQGGYFVLARFEPGADQAVLIQRPGQAPARLGQAEFEALWAGELLLCACAAS 133
Query 132 PDARVDEYIKPYEANWFWSIVLKDWKRYIDIMFASLIANILALATIIFSMQVYDRVVPSQ 191
P + + ++ +WF ++K +++ SL+ ++L T +F V D+V+ +
Sbjct 134 PT----QALARFDFSWFIPALVKHRHLIGEVLLISLVLQFISLLTPLFFQVVMDKVLVNN 189
Query 192 SIPTLWVLAGGVFIAAIFEFVLRVSRIYLSDIIGKRADLKISDRVFGHALRIKNKE-RSK 250
++ TL V+A G A +FE +L R YL + D+++ R++ H LR+ +++
Sbjct 190 AMETLNVIAVGFLAAILFEALLTGIRTYLFAHTSSKLDVELGARLYAHLLRLPLAYFQAR 249
Query 251 STGTFISQIRELEGVRELVTSTTITAIADLPFFLLFLVILWIIGGHVFWVVVIMVPLMIL 310
G ++++RELE +R +T +T + D+ F ++F+ +++ + VV+ +P L
Sbjct 250 RVGDSVARVRELEHIRAFLTGNAVTVLLDVVFSVVFIAVMFFYSVKLTLVVLAALPCYFL 309
Query 311 PGILAQKKLAKLAQEGMRESAIRNAILVEAVQGIEDIKLLRAESRFQNQWNHMNELSADY 370
++ L + A A LVE V GI+ +K L E ++Q W+
Sbjct 310 LSLVLTPVLRRRLDVKFNRGAENQAFLVETVSGIDTVKSLAVEPQWQRNWDRQLAGYVAA 369
Query 371 SMQQRKIVGVLSAWTQKLQGLTYALVVLVGCFAVMDGEMTTGALVACSILSSRMLGPISQ 430
+ + + + + L V+ VG V+ MT G LVA ++LS + P+ +
Sbjct 370 GLSVANVAMLANTGVTLISRLVALGVLWVGATEVVAQRMTVGELVAFNMLSGHVTQPVIR 429
Query 431 ITGVLGRLQQAKVAKQSLDELMKKPVDQP-DRAHLVHKPVIHGDYDLSNVVFQYNPEDSK 489
+ + QQ V+ Q L +++ + D+A L P + G +L V F+Y P D+
Sbjct 430 LAQLWNDFQQTGVSMQRLGDILNCRTEVAGDKAQL---PALRGSIELDRVSFRYRP-DAA 485
Query 490 PNLAIQKLRIKAGEKIAILGRNGAGKSTLLQLLSGMQSPINGKLTLDDLELSLIDPADIR 549
L LRI GE + ++GR+G+GKSTL +L+ M G++ +D ++ ++D A +R
Sbjct 486 DALRNVSLRIAPGEVVGVVGRSGSGKSTLTRLIQRMFVADRGRVLIDGHDIGIVDSASLR 545
Query 550 RDMGLLNQNASLFYGTIRENLTLGAPLANDHEIIKALKVTGALSFVEEKKEGLDHIILEG 609
R +G++ Q ++LF ++R+N+ L P A+ HE++ A ++ GA F+ + EG D ++ E
Sbjct 546 RQLGVVLQESTLFNRSVRDNIALTRPGASMHEVVAAARLAGAHEFICQLPEGYDTMLGEN 605
Query 610 GVGFSGGQRQALLLARLLIRQPNILLLDEPTAAIDDVSEKQLIDHLKQWLAHRTLVVATH 669
GVG SGGQRQ + +AR LI +P +L+LDE T+A+D SE + +++ RT+++ H
Sbjct 606 GVGLSGGQRQRIGIARALIHRPRVLILDEATSALDYESEHIIQRNMRDICDGRTVIIIAH 665
Query 670 RRAVLELVDRIIVINDGKIVMDGPRDQIL 698
R + + DRI+V+ G++ G + +L
Sbjct 666 RLSAVRCADRIVVMEGGEVAECGSHETLL 694
>P08716 Alpha-hemolysin translocation ATP-binding protein HlyB
[Escherichia coli]
Length=707
Score = 280 bits (717), Expect = 4e-87
Identities = 184/694 (27%), Positives = 349/694 (50%), Gaps = 16/694 (2%)
Query 12 LQAVLTIARHYRIESSEERIRLQLDWNQNQNPEEVLELMCRQVGLSLRVAKFNSDLLNPW 71
L A+ +A+++ + + E I+ + D + L + + L ++ K D LN
Sbjct 11 LYALEILAQYHNVSVNPEEIKHRFDTDGTGLGLTSWLLAAKSLELKVKQVKKTIDRLNFI 70
Query 72 RLPVIAEFKDGQIGVVDKADTEGNVSIQLSGDHGLSQSFAIDSLKGLIK-HIYIMRPESS 130
LP + +DG+ ++ K E N + + + + L + HI ++ SS
Sbjct 71 FLPALVWREDGRHFILTKISKEVNRYLIFDLEQRNPRVLEQSEFEALYQGHIILITSRSS 130
Query 131 IPDARVDEYIKPYEANWFWSIVLKDWKRYIDIMFASLIANILALATIIFSMQVYDRVVPS 190
+ + ++ WF ++K + +I+ + S+ + AL T +F V D+V+
Sbjct 131 VTGK-----LAKFDFTWFIPAIIKYRRIFIETLVVSVFLQLFALITPLFFQVVMDKVLVH 185
Query 191 QSIPTLWVLAGGVFIAAIFEFVLRVSRIYLSDIIGKRADLKISDRVFGHALRIK-NKERS 249
+ TL V+ + + +FE +L R Y+ R D+++ ++F H L + + S
Sbjct 186 RGFSTLNVITVALSVVVVFEIILSGLRTYIFAHSTSRIDVELGAKLFRHLLALPISYFES 245
Query 250 KSTGTFISQIRELEGVRELVTSTTITAIADLPFFLLFLVILWIIGGHVFWVVVIMVPLMI 309
+ G ++++REL+ +R +T +T++ DL F L+F ++W + V++ +P
Sbjct 246 RRVGDTVARVRELDQIRNFLTGQALTSVLDLLFSLIFFAVMWYYSPKLTLVILFSLPCYA 305
Query 310 LPGILAQKKLAKLAQEGMRESAIRNAILVEAVQGIEDIKLLRAESRFQNQWNHMNELSAD 369
+ L + + +A + LVE+V I IK + + N W+ A
Sbjct 306 AWSVFISPILRRRLDDKFSRNADNQSFLVESVTAINTIKAMAVSPQMTNIWDKQ---LAG 362
Query 370 YSMQQRKIVGVLSAWTQKLQGLTYALVVL---VGCFAVMDGEMTTGALVACSILSSRMLG 426
Y K+ + + Q +Q + ++++ +G V+ G+++ G L+A ++L+ +++
Sbjct 363 YVAAGFKVTVLATIGQQGIQLIQKTVMIINLWLGAHLVISGDLSIGQLIAFNMLAGQIVA 422
Query 427 PISQITGVLGRLQQAKVAKQSLDELMKKPVDQPDRAHLVHKPVIHGDYDLSNVVFQYNPE 486
P+ ++ + QQ ++ L +++ P + + P I+GD N+ F+Y P
Sbjct 423 PVIRLAQIWQDFQQVGISVTRLGDVLNSPTESYHGKLTL--PEINGDITFRNIRFRYKP- 479
Query 487 DSKPNLAIQKLRIKAGEKIAILGRNGAGKSTLLQLLSGMQSPINGKLTLDDLELSLIDPA 546
DS L L IK GE I I+GR+G+GKSTL +L+ P NG++ +D +L+L DP
Sbjct 480 DSPVILDNINLSIKQGEVIGIVGRSGSGKSTLTKLIQRFYIPENGQVLIDGHDLALADPN 539
Query 547 DIRRDMGLLNQNASLFYGTIRENLTLGAPLANDHEIIKALKVTGALSFVEEKKEGLDHII 606
+RR +G++ Q+ L +I +N++L P + ++I A K+ GA F+ E +EG + I+
Sbjct 540 WLRRQVGVVLQDNVLLNRSIIDNISLANPGMSVEKVIYAAKLAGAHDFISELREGYNTIV 599
Query 607 LEGGVGFSGGQRQALLLARLLIRQPNILLLDEPTAAIDDVSEKQLIDHLKQWLAHRTLVV 666
E G G SGGQRQ + +AR L+ P IL+ DE T+A+D SE ++ ++ + RT+++
Sbjct 600 GEQGAGLSGGQRQRIAIARALVNNPKILIFDEATSALDYESEHVIMRNMHKICKGRTVII 659
Query 667 ATHRRAVLELVDRIIVINDGKIVMDGPRDQILKQ 700
HR + ++ DRIIV+ GKIV G ++L +
Sbjct 660 IAHRLSTVKNADRIIVMEKGKIVEQGKHKELLSE 693
>P55122 Leukotoxin translocation ATP-binding protein LktB [Pasteurella
haemolytica-like sp. (strain 5943B)]
Length=708
Score = 279 bits (713), Expect = 1e-86
Identities = 187/692 (27%), Positives = 345/692 (50%), Gaps = 10/692 (1%)
Query 12 LQAVLTIARHYRIESSEERIRLQLDWNQNQNPEEVLELMCRQVGLSLRVAKFNSDLLNPW 71
L A+ +A+++ I + E I+ + D L + + L + K L+
Sbjct 12 LVALKMLAQYHNIPLNPEEIKHKFDIEGKGLTLTSWLLAAKSLELKAKHIKKEISRLHLV 71
Query 72 RLPVIAEFKDGQIGVVDKADTEGNVSIQLSGDHGLSQSFAIDSLKGLIK-HIYIMRPESS 130
LP + +G+ ++ K DT+ + + + + + + + + I ++ +S
Sbjct 72 NLPALVWQDNGKHFLLVKIDTDKKRYLTYNLEQDAPKILSQEEFESCYQGKIILVTSRAS 131
Query 131 IPDARVDEYIKPYEANWFWSIVLKDWKRYIDIMFASLIANILALATIIFSMQVYDRVVPS 190
I V + K ++ WF V+K K +++ + S+ I AL T +F V D+V+
Sbjct 132 I----VGQLAK-FDFTWFIPAVIKYRKIFLETLLVSIFLQIFALITPLFFQVVMDKVLVH 186
Query 191 QSIPTLWVLAGGVFIAAIFEFVLRVSRIYLSDIIGKRADLKISDRVFGHALRIK-NKERS 249
+ TL ++ + I IFE VL R Y+ R D+++ R+F H L + + +
Sbjct 187 RGFSTLNIITVALAIVIIFEIVLSGLRTYIFAHSTSRIDVELGARLFRHLLALPISYFEN 246
Query 250 KSTGTFISQIRELEGVRELVTSTTITAIADLPFFLLFLVILWIIGGHVFWVVVIMVPLMI 309
+ G ++++REL+ +R +T +T++ DL F +F ++W + V++ +P I
Sbjct 247 RRVGDTVARVRELDQIRNFLTGQALTSVLDLLFSFIFFAVMWYYSPKLTLVILGSLPCYI 306
Query 310 LPGILAQKKLAKLAQEGMRESAIRNAILVEAVQGIEDIKLLRAESRFQNQWNHMNELSAD 369
L I L + + A A LVE+V I IK + + + W+
Sbjct 307 LWSIFISPILRRRLDDKFARGADNQAFLVESVTAINMIKAMAVSPQMTDTWDKQLASYVS 366
Query 370 YSMQQRKIVGVLSAWTQKLQGLTYALVVLVGCFAVMDGEMTTGALVACSILSSRMLGPIS 429
S + + + Q +Q + + +G V+ G+++ G L+A ++LS +++ P+
Sbjct 367 SSFRVTVLATIGQQGVQLIQKTVMVINLWLGAHLVISGDLSIGQLIAFNMLSGQVIAPVI 426
Query 430 QITGVLGRLQQAKVAKQSLDELMKKPVDQPDRAHLVHKPVIHGDYDLSNVVFQYNPEDSK 489
++ + Q ++ L +++ P +Q + P I GD N+ F+Y P D+
Sbjct 427 RLAQLWQDFTQVGISVTRLGDVLNSPTEQYQGK--LSLPEIQGDIAFKNIRFRYKP-DAP 483
Query 490 PNLAIQKLRIKAGEKIAILGRNGAGKSTLLQLLSGMQSPINGKLTLDDLELSLIDPADIR 549
L L IK GE I I+GR+G+GKSTL +LL P NG++ +D +L+L DP +R
Sbjct 484 TILNNVNLEIKKGEVIGIVGRSGSGKSTLTKLLQRFYIPENGQVLIDGHDLALADPNWLR 543
Query 550 RDMGLLNQNASLFYGTIRENLTLGAPLANDHEIIKALKVTGALSFVEEKKEGLDHIILEG 609
R +G++ Q+ L +IREN+ L P + +I A K+ GA F+ + +EG + I+ E
Sbjct 544 RQIGVVLQDNVLLNRSIRENIALSEPGMSMERVIYAAKLAGAHDFISDVREGYNTIVGEQ 603
Query 610 GVGFSGGQRQALLLARLLIRQPNILLLDEPTAAIDDVSEKQLIDHLKQWLAHRTLVVATH 669
G G SGGQRQ + +AR L+ P IL+ DE T+A+D SE ++ ++++ RT+++ H
Sbjct 604 GAGLSGGQRQRIAIARALVNNPKILIFDEATSALDYESEHIIMQNMQKICQGRTVILIAH 663
Query 670 RRAVLELVDRIIVINDGKIVMDGPRDQILKQS 701
R + ++ DRIIV+ G+IV G +++L+ +
Sbjct 664 RLSTVKNADRIIVMEKGEIVEQGKHNELLQNN 695
Lambda K H a alpha
0.322 0.138 0.400 0.792 4.96
Gapped
Lambda K H a alpha sigma
0.267 0.0410 0.140 1.90 42.6 43.6
Effective search space used: 8066980
Database: a8c07e3f8693469cb0249d4e104b22f4.SwissProt.fasta
Posted date: May 9, 2024 10:40 AM
Number of letters in database: 13,456
Number of sequences in database: 19
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Neighboring words threshold: 11
Window for multiple hits: 40
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Data ...
