BLASTP 2.12.0+
Reference: Stephen F. Altschul, Thomas L. Madden, Alejandro A.
Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J.
Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of
protein database search programs", Nucleic Acids Res. 25:3389-3402.
Reference for composition-based statistics: Alejandro A. Schaffer,
L. Aravind, Thomas L. Madden, Sergei Shavirin, John L. Spouge, Yuri
I. Wolf, Eugene V. Koonin, and Stephen F. Altschul (2001),
"Improving the accuracy of PSI-BLAST protein database searches with
composition-based statistics and other refinements", Nucleic Acids
Res. 29:2994-3005.
Database: 846e7df37be6f93e9ff8bf2f8fc5ee17.SwissProt.fasta
16 sequences; 4,077 total letters
Query= ACIAD1565
Length=255
Score E
Sequences producing significant alignments: (Bits) Value
P9WGQ7 Uncharacterized oxidoreductase Rv1144 [Mycobacterium tuber... 255 4e-89
P9WGQ6 Uncharacterized oxidoreductase MT1177 [Mycobacterium tuber... 255 4e-89
O02691 3-hydroxyacyl-CoA dehydrogenase type-2 [Bos taurus] 251 3e-87
O70351 3-hydroxyacyl-CoA dehydrogenase type-2 [Rattus norvegicus] 249 1e-86
Q99714 3-hydroxyacyl-CoA dehydrogenase type-2 [Homo sapiens] 248 2e-86
O08756 3-hydroxyacyl-CoA dehydrogenase type-2 [Mus musculus] 245 5e-85
O18404 3-hydroxyacyl-CoA dehydrogenase type-2 [Drosophila melanog... 238 3e-82
P66782 Uncharacterized oxidoreductase Mb1385 [Mycobacterium bovis... 130 1e-40
P9WGR9 Uncharacterized oxidoreductase Rv1350 [Mycobacterium tuber... 130 1e-40
P9WGR8 Uncharacterized oxidoreductase MT1393 [Mycobacterium tuber... 130 1e-40
G5DGA8 Ipsdienol dehydrogenase [Ips pini] 130 2e-40
Q9X248 3-oxoacyl-[acyl-carrier-protein] reductase FabG [Thermotog... 130 2e-40
Q92506 (3R)-3-hydroxyacyl-CoA dehydrogenase [Homo sapiens] 127 4e-39
Q6MGB5 (3R)-3-hydroxyacyl-CoA dehydrogenase [Rattus norvegicus] 124 9e-38
P50171 (3R)-3-hydroxyacyl-CoA dehydrogenase [Mus musculus] 123 2e-37
Q9XT00 (3R)-3-hydroxyacyl-CoA dehydrogenase [Sus scrofa] 121 9e-37
>P9WGQ7 Uncharacterized oxidoreductase Rv1144 [Mycobacterium tuberculosis
(strain ATCC 25618 / H37Rv)]
Length=250
Score = 255 bits (651), Expect = 4e-89
Identities = 149/259 (58%), Positives = 181/259 (70%), Gaps = 14/259 (5%)
Query 1 MRLKGNVVLVTGGASGLGGAVVQRLAEQGARLVIIDLNQSLGEQLARQVSGL-----FVQ 55
M+ K V +VTGGASGLG A +RL + GA++V++DL G+ + V GL F Q
Sbjct 1 MKTKDAVAVVTGGASGLGLATTKRLLDAGAQVVVVDLR---GDDV---VGGLGDRARFAQ 54
Query 56 ADVTNEEQIDQAFQQAEEFYKKKVRVVVNCAGIGPPGKAIDREGNPLALSTFSKIININL 115
ADVT+E + A + A+ VRVVVNCAG G + + R+G L+ F KI++INL
Sbjct 55 ADVTDEAAVSNALELADSL--GPVRVVVNCAGTGNAIRVLSRDG-VFPLAAFRKIVDINL 111
Query 116 NGTFNVLSKFAARLHREAVEGEERGVIINTASVAAFDGQIGQPAYAASKAGVVGMTLPLA 175
GTFNVL A R+ + GEERGVIINTASVAAFDGQIGQ AY+ASK GVVGMTLP+A
Sbjct 112 VGTFNVLRLGAERIAKTEPIGEERGVIINTASVAAFDGQIGQAAYSASKGGVVGMTLPIA 171
Query 176 REFARYGIRVMTIAPGIFLTPLLATLPQDVQDSLGAQVPFPSRLGQPDEFAQLVESIILN 235
R+ A IRV+TIAPG+F TPLLA+LP + + SLG QVP PSRLG PDE+ LV II N
Sbjct 172 RDLASKLIRVVTIAPGLFDTPLLASLPAEAKASLGQQVPHPSRLGNPDEYGALVLHIIEN 231
Query 236 PMLNGEVIRLDGAIRMTAK 254
PMLNGEVIRLDGAIRM +
Sbjct 232 PMLNGEVIRLDGAIRMAPR 250
>P9WGQ6 Uncharacterized oxidoreductase MT1177 [Mycobacterium tuberculosis
(strain CDC 1551 / Oshkosh)]
Length=250
Score = 255 bits (651), Expect = 4e-89
Identities = 149/259 (58%), Positives = 181/259 (70%), Gaps = 14/259 (5%)
Query 1 MRLKGNVVLVTGGASGLGGAVVQRLAEQGARLVIIDLNQSLGEQLARQVSGL-----FVQ 55
M+ K V +VTGGASGLG A +RL + GA++V++DL G+ + V GL F Q
Sbjct 1 MKTKDAVAVVTGGASGLGLATTKRLLDAGAQVVVVDLR---GDDV---VGGLGDRARFAQ 54
Query 56 ADVTNEEQIDQAFQQAEEFYKKKVRVVVNCAGIGPPGKAIDREGNPLALSTFSKIININL 115
ADVT+E + A + A+ VRVVVNCAG G + + R+G L+ F KI++INL
Sbjct 55 ADVTDEAAVSNALELADSL--GPVRVVVNCAGTGNAIRVLSRDG-VFPLAAFRKIVDINL 111
Query 116 NGTFNVLSKFAARLHREAVEGEERGVIINTASVAAFDGQIGQPAYAASKAGVVGMTLPLA 175
GTFNVL A R+ + GEERGVIINTASVAAFDGQIGQ AY+ASK GVVGMTLP+A
Sbjct 112 VGTFNVLRLGAERIAKTEPIGEERGVIINTASVAAFDGQIGQAAYSASKGGVVGMTLPIA 171
Query 176 REFARYGIRVMTIAPGIFLTPLLATLPQDVQDSLGAQVPFPSRLGQPDEFAQLVESIILN 235
R+ A IRV+TIAPG+F TPLLA+LP + + SLG QVP PSRLG PDE+ LV II N
Sbjct 172 RDLASKLIRVVTIAPGLFDTPLLASLPAEAKASLGQQVPHPSRLGNPDEYGALVLHIIEN 231
Query 236 PMLNGEVIRLDGAIRMTAK 254
PMLNGEVIRLDGAIRM +
Sbjct 232 PMLNGEVIRLDGAIRMAPR 250
>O02691 3-hydroxyacyl-CoA dehydrogenase type-2 [Bos taurus]
Length=261
Score = 251 bits (640), Expect = 3e-87
Identities = 141/253 (56%), Positives = 177/253 (70%), Gaps = 5/253 (2%)
Query 3 LKGNVVLVTGGASGLGGAVVQRLAEQGARLVIIDLNQSLGEQLARQV--SGLFVQADVTN 60
+KG V L+TGGASGLG A +RL QGA V++DL S GE A+++ S F ADVT+
Sbjct 8 VKGLVALITGGASGLGLATAERLVGQGATAVLLDLPNSDGETQAKKLGKSCAFAPADVTS 67
Query 61 EEQIDQAFQQAEEFYKKKVRVVVNCAGIGPPGKAID-REGNPLALSTFSKIININLNGTF 119
E+ + A A E + + V V VNCAGI K + ++ L F ++IN+NL GTF
Sbjct 68 EKDVQAALTLAREKFGR-VDVAVNCAGIAVASKTYNLKKSQAHTLEDFQRVINVNLIGTF 126
Query 120 NVLSKFAARL-HREAVEGEERGVIINTASVAAFDGQIGQPAYAASKAGVVGMTLPLAREF 178
NV+ A + E +G +RGVIINTASVAAF+GQ+GQ AY+ASK G+VGMTLP+AR+
Sbjct 127 NVIRLVAGEMGQNEPDQGGQRGVIINTASVAAFEGQVGQAAYSASKGGIVGMTLPIARDL 186
Query 179 ARYGIRVMTIAPGIFLTPLLATLPQDVQDSLGAQVPFPSRLGQPDEFAQLVESIILNPML 238
A GIRVMTIAPG+F TPLL TLP V++ L +QVPFPSRLG P E+A LV++II N L
Sbjct 187 APMGIRVMTIAPGLFGTPLLTTLPDKVRNFLASQVPFPSRLGDPAEYAHLVQAIIENSFL 246
Query 239 NGEVIRLDGAIRM 251
NGEVIRLDGAIRM
Sbjct 247 NGEVIRLDGAIRM 259
>O70351 3-hydroxyacyl-CoA dehydrogenase type-2 [Rattus norvegicus]
Length=261
Score = 249 bits (636), Expect = 1e-86
Identities = 136/253 (54%), Positives = 180/253 (71%), Gaps = 5/253 (2%)
Query 3 LKGNVVLVTGGASGLGGAVVQRLAEQGARLVIIDLNQSLGEQLARQVSG--LFVQADVTN 60
+KG V ++TGGASGLG + +RL QGA V++D+ S GE A+++ G +F A+VT+
Sbjct 8 VKGLVAVITGGASGLGLSTAKRLVGQGATAVLLDVPNSEGETEAKKLGGNCIFAPANVTS 67
Query 61 EEQIDQAFQQAEEFYKKKVRVVVNCAGIGPPGKAIDREGNPL-ALSTFSKIININLNGTF 119
E+++ A A+E + + + V VNCAGI K + N + L F ++IN+NL GTF
Sbjct 68 EKEVQAALTLAKEKFGR-IDVAVNCAGIAVAIKTYHEKKNQVHTLEDFQRVINVNLIGTF 126
Query 120 NVLSKFAARL-HREAVEGEERGVIINTASVAAFDGQIGQPAYAASKAGVVGMTLPLAREF 178
NV+ A + E +G +RGVIINTASVAAF+GQ+GQ AY+ASK G+VGMTLP+AR+
Sbjct 127 NVIRLVAGVMGQNEPDQGGQRGVIINTASVAAFEGQVGQAAYSASKGGIVGMTLPIARDL 186
Query 179 ARYGIRVMTIAPGIFLTPLLATLPQDVQDSLGAQVPFPSRLGQPDEFAQLVESIILNPML 238
A GIRV+TIAPG+F TPLL TLP V++ L +QVPFPSRLG P E+A LV+ +I NP L
Sbjct 187 APIGIRVVTIAPGLFATPLLTTLPDKVRNFLASQVPFPSRLGDPAEYAHLVQMVIENPFL 246
Query 239 NGEVIRLDGAIRM 251
NGEVIRLDGAIRM
Sbjct 247 NGEVIRLDGAIRM 259
>Q99714 3-hydroxyacyl-CoA dehydrogenase type-2 [Homo sapiens]
Length=261
Score = 248 bits (634), Expect = 2e-86
Identities = 137/253 (54%), Positives = 179/253 (71%), Gaps = 5/253 (2%)
Query 3 LKGNVVLVTGGASGLGGAVVQRLAEQGARLVIIDLNQSLGEQLARQVSG--LFVQADVTN 60
+KG V ++TGGASGLG A +RL QGA V++DL S GE A+++ +F ADVT+
Sbjct 8 VKGLVAVITGGASGLGLATAERLVGQGASAVLLDLPNSGGEAQAKKLGNNCVFAPADVTS 67
Query 61 EEQIDQAFQQAEEFYKKKVRVVVNCAGIGPPGKAID-REGNPLALSTFSKIININLNGTF 119
E+ + A A+ + + V V VNCAGI K + ++G L F +++++NL GTF
Sbjct 68 EKDVQTALALAKGKFGR-VDVAVNCAGIAVASKTYNLKKGQTHTLEDFQRVLDVNLMGTF 126
Query 120 NVLSKFAARL-HREAVEGEERGVIINTASVAAFDGQIGQPAYAASKAGVVGMTLPLAREF 178
NV+ A + E +G +RGVIINTASVAAF+GQ+GQ AY+ASK G+VGMTLP+AR+
Sbjct 127 NVIRLVAGEMGQNEPDQGGQRGVIINTASVAAFEGQVGQAAYSASKGGIVGMTLPIARDL 186
Query 179 ARYGIRVMTIAPGIFLTPLLATLPQDVQDSLGAQVPFPSRLGQPDEFAQLVESIILNPML 238
A GIRVMTIAPG+F TPLL +LP+ V + L +QVPFPSRLG P E+A LV++II NP L
Sbjct 187 APIGIRVMTIAPGLFGTPLLTSLPEKVCNFLASQVPFPSRLGDPAEYAHLVQAIIENPFL 246
Query 239 NGEVIRLDGAIRM 251
NGEVIRLDGAIRM
Sbjct 247 NGEVIRLDGAIRM 259
>O08756 3-hydroxyacyl-CoA dehydrogenase type-2 [Mus musculus]
Length=261
Score = 245 bits (625), Expect = 5e-85
Identities = 137/253 (54%), Positives = 180/253 (71%), Gaps = 5/253 (2%)
Query 3 LKGNVVLVTGGASGLGGAVVQRLAEQGARLVIIDLNQSLGEQLARQV--SGLFVQADVTN 60
+KG V +VTGGASG A +RL QGA V++D+ S GE A+++ S +F A+VT+
Sbjct 8 VKGLVAVVTGGASGPWLATAKRLVGQGATAVLLDVPDSEGESQAKKLGESCIFAPANVTS 67
Query 61 EEQIDQAFQQAEEFYKKKVRVVVNCAGIGPPGKAIDREGNPL-ALSTFSKIININLNGTF 119
E++I A A+E + + + V VNCAGI K ++ N + L F ++IN+NL GTF
Sbjct 68 EKEIQAALTLAKEKFGR-IDVAVNCAGIAVAIKTYHQKKNKIHTLEDFQRVINVNLIGTF 126
Query 120 NVLSKFAARL-HREAVEGEERGVIINTASVAAFDGQIGQPAYAASKAGVVGMTLPLAREF 178
NV+ A + E +G +RGVIINTASVAAF+GQ+GQ AY+ASK G+ GMTLP+AR+
Sbjct 127 NVIRLVAGEMGQNEPDQGGQRGVIINTASVAAFEGQVGQAAYSASKGGIDGMTLPIARDL 186
Query 179 ARYGIRVMTIAPGIFLTPLLATLPQDVQDSLGAQVPFPSRLGQPDEFAQLVESIILNPML 238
A GIRV+TIAPG+F TPLL TLP+ V++ L +QVPFPSRLG P E+A LV++II NP L
Sbjct 187 APTGIRVVTIAPGLFATPLLTTLPEKVRNFLASQVPFPSRLGDPAEYAHLVQTIIENPFL 246
Query 239 NGEVIRLDGAIRM 251
NGEVIRLDGAIRM
Sbjct 247 NGEVIRLDGAIRM 259
>O18404 3-hydroxyacyl-CoA dehydrogenase type-2 [Drosophila melanogaster]
Length=255
Score = 238 bits (606), Expect = 3e-82
Identities = 129/253 (51%), Positives = 175/253 (69%), Gaps = 5/253 (2%)
Query 3 LKGNVVLVTGGASGLGGAVVQRLAEQGARLVIIDLNQSLGEQLARQVSG--LFVQADVTN 60
+K V LVTGGASGLG A +RLA+QGA +++ DL S G ++A+++ +FV DVT+
Sbjct 2 IKNAVSLVTGGASGLGRATAERLAKQGASVILADLPSSKGNEVAKELGDKVVFVPVDVTS 61
Query 61 EEQIDQAFQQAEEFYKKKVRVVVNCAGIGPPGKAIDREGNPL-ALSTFSKIININLNGTF 119
E+ + A Q A++ + + + + VNCAG K + N L F ++ININ GTF
Sbjct 62 EKDVSAALQTAKDKFGR-LDLTVNCAGTATAVKTFNFNKNVAHRLEDFQRVININTVGTF 120
Query 120 NVLSKFAARLH-REAVEGEERGVIINTASVAAFDGQIGQPAYAASKAGVVGMTLPLAREF 178
NV+ A + E + +RGVI+NTASVAAFDGQIGQ AY+ASKA VVGMTLP+AR+
Sbjct 121 NVIRLSAGLMGANEPNQDGQRGVIVNTASVAAFDGQIGQAAYSASKAAVVGMTLPIARDL 180
Query 179 ARYGIRVMTIAPGIFLTPLLATLPQDVQDSLGAQVPFPSRLGQPDEFAQLVESIILNPML 238
+ GIR+ TIAPG+F TP+LA LP+ V+ L +PFP RLG+P E+A LV++I NP+L
Sbjct 181 STQGIRICTIAPGLFNTPMLAALPEKVRTFLAKSIPFPQRLGEPSEYAHLVQAIYENPLL 240
Query 239 NGEVIRLDGAIRM 251
NGEVIR+DGA+RM
Sbjct 241 NGEVIRIDGALRM 253
>P66782 Uncharacterized oxidoreductase Mb1385 [Mycobacterium bovis
(strain ATCC BAA-935 / AF2122/97)]
Length=247
Score = 130 bits (328), Expect = 1e-40
Identities = 89/251 (35%), Positives = 137/251 (55%), Gaps = 18/251 (7%)
Query 3 LKGNVVLVTGGASGLGGAVVQRLAEQGARLVIIDLNQSLGEQLARQVSG----LFVQADV 58
L ++TGGA GLG A+ QR +GAR+V+ D+N E A+++ G L V+ DV
Sbjct 5 LNARTAVITGGAQGLGLAIGQRFVAEGARVVLGDVNLEATEVAAKRLGGDDVALAVRCDV 64
Query 59 TNEEQIDQAFQQAEEFYKKKVRVVVNCAGIGPPGKAIDREGNPLALSTFSKIININLNGT 118
T + +D + A E + + V+VN AGI D + F ++I ++L GT
Sbjct 65 TQADDVDILIRTAVERFGG-LDVMVNNAGI-----TRDATMRTMTEEQFDQVIAVHLKGT 118
Query 119 FNVLSKFAARLHREAVEGEERGVIINTASVAAFDGQIGQPAYAASKAGVVGMTLPLAREF 178
+N ++ AA + RE +RG I+N +SV+ G +GQ Y+A+KAG+VGMT A+E
Sbjct 119 WNG-TRLAAAIMRE----RKRGAIVNMSSVSGKVGMVGQTNYSAAKAGIVGMTKAAAKEL 173
Query 179 ARYGIRVMTIAPGIFLTPLLATLPQDVQDSLGAQVPFPSRLGQPDEFAQLVESII--LNP 236
A GIRV IAPG+ + + +PQ + D A+VP R G+P E A + + L+
Sbjct 174 AHLGIRVNAIAPGLIRSAMTEAMPQRIWDQKLAEVPM-GRAGEPSEVASVAVFLASDLSS 232
Query 237 MLNGEVIRLDG 247
+ G V+ + G
Sbjct 233 YMTGTVLDVTG 243
>P9WGR9 Uncharacterized oxidoreductase Rv1350 [Mycobacterium tuberculosis
(strain ATCC 25618 / H37Rv)]
Length=247
Score = 130 bits (328), Expect = 1e-40
Identities = 89/251 (35%), Positives = 137/251 (55%), Gaps = 18/251 (7%)
Query 3 LKGNVVLVTGGASGLGGAVVQRLAEQGARLVIIDLNQSLGEQLARQVSG----LFVQADV 58
L ++TGGA GLG A+ QR +GAR+V+ D+N E A+++ G L V+ DV
Sbjct 5 LNARTAVITGGAQGLGLAIGQRFVAEGARVVLGDVNLEATEVAAKRLGGDDVALAVRCDV 64
Query 59 TNEEQIDQAFQQAEEFYKKKVRVVVNCAGIGPPGKAIDREGNPLALSTFSKIININLNGT 118
T + +D + A E + + V+VN AGI D + F ++I ++L GT
Sbjct 65 TQADDVDILIRTAVERFGG-LDVMVNNAGI-----TRDATMRTMTEEQFDQVIAVHLKGT 118
Query 119 FNVLSKFAARLHREAVEGEERGVIINTASVAAFDGQIGQPAYAASKAGVVGMTLPLAREF 178
+N ++ AA + RE +RG I+N +SV+ G +GQ Y+A+KAG+VGMT A+E
Sbjct 119 WNG-TRLAAAIMRE----RKRGAIVNMSSVSGKVGMVGQTNYSAAKAGIVGMTKAAAKEL 173
Query 179 ARYGIRVMTIAPGIFLTPLLATLPQDVQDSLGAQVPFPSRLGQPDEFAQLVESII--LNP 236
A GIRV IAPG+ + + +PQ + D A+VP R G+P E A + + L+
Sbjct 174 AHLGIRVNAIAPGLIRSAMTEAMPQRIWDQKLAEVPM-GRAGEPSEVASVAVFLASDLSS 232
Query 237 MLNGEVIRLDG 247
+ G V+ + G
Sbjct 233 YMTGTVLDVTG 243
>P9WGR8 Uncharacterized oxidoreductase MT1393 [Mycobacterium tuberculosis
(strain CDC 1551 / Oshkosh)]
Length=247
Score = 130 bits (328), Expect = 1e-40
Identities = 89/251 (35%), Positives = 137/251 (55%), Gaps = 18/251 (7%)
Query 3 LKGNVVLVTGGASGLGGAVVQRLAEQGARLVIIDLNQSLGEQLARQVSG----LFVQADV 58
L ++TGGA GLG A+ QR +GAR+V+ D+N E A+++ G L V+ DV
Sbjct 5 LNARTAVITGGAQGLGLAIGQRFVAEGARVVLGDVNLEATEVAAKRLGGDDVALAVRCDV 64
Query 59 TNEEQIDQAFQQAEEFYKKKVRVVVNCAGIGPPGKAIDREGNPLALSTFSKIININLNGT 118
T + +D + A E + + V+VN AGI D + F ++I ++L GT
Sbjct 65 TQADDVDILIRTAVERFGG-LDVMVNNAGI-----TRDATMRTMTEEQFDQVIAVHLKGT 118
Query 119 FNVLSKFAARLHREAVEGEERGVIINTASVAAFDGQIGQPAYAASKAGVVGMTLPLAREF 178
+N ++ AA + RE +RG I+N +SV+ G +GQ Y+A+KAG+VGMT A+E
Sbjct 119 WNG-TRLAAAIMRE----RKRGAIVNMSSVSGKVGMVGQTNYSAAKAGIVGMTKAAAKEL 173
Query 179 ARYGIRVMTIAPGIFLTPLLATLPQDVQDSLGAQVPFPSRLGQPDEFAQLVESII--LNP 236
A GIRV IAPG+ + + +PQ + D A+VP R G+P E A + + L+
Sbjct 174 AHLGIRVNAIAPGLIRSAMTEAMPQRIWDQKLAEVPM-GRAGEPSEVASVAVFLASDLSS 232
Query 237 MLNGEVIRLDG 247
+ G V+ + G
Sbjct 233 YMTGTVLDVTG 243
>G5DGA8 Ipsdienol dehydrogenase [Ips pini]
Length=253
Score = 130 bits (328), Expect = 2e-40
Identities = 90/254 (35%), Positives = 138/254 (54%), Gaps = 8/254 (3%)
Query 1 MRLKGNVVLVTGGASGLGGAVVQRLAEQGARLVIIDLNQSLGEQLARQVSGLFVQADVTN 60
++++ +V LVTGG SGLG A + L +GAR+ I N+ E QV L V+ DV +
Sbjct 3 VKIQDSVYLVTGGGSGLGEATAKLLLTEGARVTIFSRNEYKNEFPHDQV--LSVKGDVRS 60
Query 61 EEQIDQAFQQAEEFYKKKVRVVVNCAGIGPPGKAIDREGN--PLALSTFSKIININLNGT 118
E + +A + + + K + V++CAG+ G + P + + I+ NL GT
Sbjct 61 ESDVKRALEATIQKFGK-LDGVMHCAGVFQNGDELFNMDTQQPGDYTVLTDIVTTNLLGT 119
Query 119 FNVLSKFAAR--LHREAVEGEERGVIINTASVAAFDGQIGQPAYAASKAGVVGMTLPLAR 176
FNV ++ A L + E ++G+IIN +S + AY+ SKA ++G++ LA+
Sbjct 120 FNV-NRLAIPYFLTNQPDEEGQKGIIINCSSTSGHSPMSSAVAYSTSKAAIIGLSYALAK 178
Query 177 EFARYGIRVMTIAPGIFLTPLLATLPQDVQDSLGAQVPFPSRLGQPDEFAQLVESIILNP 236
+ + GIRVM IAP + TP+ QD + FP+RL QP E+A V+ II P
Sbjct 179 QLSTLGIRVMDIAPALCDTPMFRRAVGFNQDIANFRNLFPARLIQPIEYANAVKHIIETP 238
Query 237 MLNGEVIRLDGAIR 250
MLNG +LDGA+R
Sbjct 239 MLNGSSYQLDGALR 252
>Q9X248 3-oxoacyl-[acyl-carrier-protein] reductase FabG [Thermotoga
maritima (strain ATCC 43589 / DSM 3109 / JCM 10099 / NBRC
100826 / MSB8)]
Length=246
Score = 130 bits (327), Expect = 2e-40
Identities = 84/256 (33%), Positives = 138/256 (54%), Gaps = 19/256 (7%)
Query 1 MRLKGNVVLVTGGASGLGGAVVQRLAEQGARLVIIDLNQSLGEQLARQVSGLFVQAD--- 57
MRL+G V L+TG ASG+G A A++GA ++ D+++ + L ++ GL + D
Sbjct 1 MRLEGKVCLITGAASGIGKATTLLFAQEGATVIAGDISKENLDSLVKEAEGLPGKVDPYV 60
Query 58 --VTNEEQIDQAFQQAEEFYKKKVRVVVNCAGIGPPGKAIDREGNPLALSTFSKIININL 115
VT+ +QI + ++ + Y + + V+VN AGI + + + +IN+NL
Sbjct 61 LNVTDRDQIKEVVEKVVQKYGR-IDVLVNNAGITRDALLVRMKEED-----WDAVINVNL 114
Query 116 NGTFNVLSKFAARLHREAVEGEERGVIINTASVAAFDGQIGQPAYAASKAGVVGMTLPLA 175
G FNV + ++ G I+N +SV G GQ YAASKAGV+GMT A
Sbjct 115 KGVFNVTQMVVPYMIKQ-----RNGSIVNVSSVVGIYGNPGQTNYAASKAGVIGMTKTWA 169
Query 176 REFARYGIRVMTIAPGIFLTPLLATLPQDVQDSLGAQVPFPSRLGQPDEFAQLVESIIL- 234
+E A IRV +APG TP+ LP+ +++ +++P R G+P+E AQ++ +
Sbjct 170 KELAGRNIRVNAVAPGFIETPMTEKLPEKARETALSRIPL-GRFGKPEEVAQVILFLASD 228
Query 235 -NPMLNGEVIRLDGAI 249
+ + G+VI +DG +
Sbjct 229 ESSYVTGQVIGIDGGL 244
>Q92506 (3R)-3-hydroxyacyl-CoA dehydrogenase [Homo sapiens]
Length=261
Score = 127 bits (319), Expect = 4e-39
Identities = 83/240 (35%), Positives = 121/240 (50%), Gaps = 22/240 (9%)
Query 2 RLKGNVVLVTGGASGLGGAVVQRLAEQGARLVIIDLNQSLGEQLARQVSG---------- 51
RL+ + LVTG SG+G AV RLA +GA + DL+++ ++ R + G
Sbjct 8 RLRSALALVTGAGSGIGRAVSVRLAGEGATVAACDLDRAAAQETVRLLGGPGSKEGPPRG 67
Query 52 --LFVQADVTNEEQIDQAFQQAEEFYKKKVRVVVNCAGIGPPGKAIDREGNPLALSTFSK 109
QADV+ +Q + + + VVV+CAGI + ++ + K
Sbjct 68 NHAAFQADVSEARAARCLLEQVQACFSRPPSVVVSCAGITQDEFLLH-----MSEDDWDK 122
Query 110 IININLNGTFNVLSKFAARLHREAVEGEERGVIINTASVAAFDGQIGQPAYAASKAGVVG 169
+I +NL GTF V A L V RG IIN +S+ G +GQ YAASKAGV+G
Sbjct 123 VIAVNLKGTFLVTQAAAQAL----VSNGCRGSIINISSIVGKVGNVGQTNYAASKAGVIG 178
Query 170 MTLPLAREFARYGIRVMTIAPGIFLTPLLATLPQDVQDSLGAQVPFPSRLGQPDEFAQLV 229
+T ARE R+GIR ++ PG TP+ +PQ V D + +P LG P++ A +V
Sbjct 179 LTQTAARELGRHGIRCNSVLPGFIATPMTQKVPQKVVDKITEMIPM-GHLGDPEDVADVV 237
>Q6MGB5 (3R)-3-hydroxyacyl-CoA dehydrogenase [Rattus norvegicus]
Length=259
Score = 124 bits (310), Expect = 9e-38
Identities = 82/243 (34%), Positives = 124/243 (51%), Gaps = 26/243 (11%)
Query 1 MRLKGNVVLVTGGASGLGGAVVQRLAEQGARLVIIDLNQSLGEQLARQVSG--------- 51
+RL+ + LVTG SG+G A+ RLA +GA + DL+ + + R +
Sbjct 5 LRLRSALALVTGAGSGIGRAISVRLAAEGAAVAACDLDGAAAQDTVRLLGNPGSEDREPR 64
Query 52 ---LFVQADVTNEEQIDQAFQQAEEFYKKKVRVVVNCAGIGPPGKAIDREGNPLALST-- 106
QADV+ + +Q + + + VVV+CAGI R+ L +S
Sbjct 65 GKHAAFQADVSEGPAAKRLLEQVQACFFRPPSVVVSCAGI-------TRDEFLLHMSEED 117
Query 107 FSKIININLNGTFNVLSKFAARLHREAVEGEERGVIINTASVAAFDGQIGQPAYAASKAG 166
+ ++I +NL GTF V A L V RG IIN +S+ G IGQ YA+SKAG
Sbjct 118 WDRVIAVNLKGTFLVTQAAAQAL----VSSGGRGSIINISSIVGKVGNIGQTNYASSKAG 173
Query 167 VVGMTLPLAREFARYGIRVMTIAPGIFLTPLLATLPQDVQDSLGAQVPFPSRLGQPDEFA 226
V+G+T ARE R+GIR ++ PG TP+ +P+ V+D + A +P +G P++ A
Sbjct 174 VIGLTQTAARELGRHGIRCNSVLPGFIATPMTQKMPEKVKDKVTAMIPL-GHMGDPEDVA 232
Query 227 QLV 229
+V
Sbjct 233 DVV 235
>P50171 (3R)-3-hydroxyacyl-CoA dehydrogenase [Mus musculus]
Length=259
Score = 123 bits (308), Expect = 2e-37
Identities = 81/243 (33%), Positives = 124/243 (51%), Gaps = 26/243 (11%)
Query 1 MRLKGNVVLVTGGASGLGGAVVQRLAEQGARLVIIDLNQSLGEQLARQVSG--------- 51
+RL+ + LVTG SG+G A+ RLA +GA + DL+ + + R +
Sbjct 5 LRLRSALALVTGAGSGIGRAISVRLAAEGAAVAACDLDGAAAQDTVRLLGSPGSEDGAPR 64
Query 52 ---LFVQADVTNEEQIDQAFQQAEEFYKKKVRVVVNCAGIGPPGKAIDREGNPLALST-- 106
QADV+ + ++ + + + VVV+CAGI R+ L +S
Sbjct 65 GKHAAFQADVSQGPAARRLLEEVQACFSRPPSVVVSCAGI-------TRDEFLLHMSEED 117
Query 107 FSKIININLNGTFNVLSKFAARLHREAVEGEERGVIINTASVAAFDGQIGQPAYAASKAG 166
+ ++I +NL GTF V A L V RG IIN +S+ G IGQ YA+SKAG
Sbjct 118 WDRVIAVNLKGTFLVTQAAAQAL----VSSGGRGSIINISSIIGKVGNIGQTNYASSKAG 173
Query 167 VVGMTLPLAREFARYGIRVMTIAPGIFLTPLLATLPQDVQDSLGAQVPFPSRLGQPDEFA 226
V+G+T ARE R+GIR ++ PG TP+ +P+ V+D + A +P +G P++ A
Sbjct 174 VIGLTQTAARELGRHGIRCNSVLPGFIATPMTQKMPEKVKDKVTAMIPL-GHMGDPEDVA 232
Query 227 QLV 229
+V
Sbjct 233 DVV 235
>Q9XT00 (3R)-3-hydroxyacyl-CoA dehydrogenase [Sus scrofa]
Length=259
Score = 121 bits (303), Expect = 9e-37
Identities = 83/243 (34%), Positives = 122/243 (50%), Gaps = 26/243 (11%)
Query 1 MRLKGNVVLVTGGASGLGGAVVQRLAEQGARLVIIDLNQSLGEQLARQVSG--------- 51
+RL+ + LVTG SG+G AV RLA +GA + DL+ + ++ + + G
Sbjct 5 LRLRSALALVTGAGSGIGRAVSVRLAAEGAAVAACDLDGAAAQETVQLLGGPGSEKGAPS 64
Query 52 ---LFVQADVTNEEQIDQAFQQAEEFYKKKVRVVVNCAGIGPPGKAIDREGNPLALST-- 106
QADV+ E + +Q + ++ + VVV+CAGI R+ L +S
Sbjct 65 GPMAAFQADVSEAETARRLLEQVQAYFFRPPSVVVSCAGI-------TRDEFLLRMSEDD 117
Query 107 FSKIININLNGTFNVLSKFAARLHREAVEGEERGVIINTASVAAFDGQIGQPAYAASKAG 166
+ K+I +NL G F V A L G IIN +S+ G +GQ YAASKAG
Sbjct 118 WDKVIAVNLKGIFLVTQAAAQALVSSGCPGS----IINISSIIGKVGNMGQTNYAASKAG 173
Query 167 VVGMTLPLAREFARYGIRVMTIAPGIFLTPLLATLPQDVQDSLGAQVPFPSRLGQPDEFA 226
V+G+T +ARE RY IR ++ PG TP+ +PQ V D + +P LG P + A
Sbjct 174 VIGLTQAVARELGRYRIRCNSVLPGFIKTPMAQKVPQKVLDKVVGMIPM-GHLGGPPDVA 232
Query 227 QLV 229
+V
Sbjct 233 DVV 235
Lambda K H a alpha
0.322 0.139 0.388 0.792 4.96
Gapped
Lambda K H a alpha sigma
0.267 0.0410 0.140 1.90 42.6 43.6
Effective search space used: 718468
Database: 846e7df37be6f93e9ff8bf2f8fc5ee17.SwissProt.fasta
Posted date: May 9, 2024 3:38 PM
Number of letters in database: 4,077
Number of sequences in database: 16
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Neighboring words threshold: 11
Window for multiple hits: 40
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Data ...
