BLASTP 2.12.0+
Reference: Stephen F. Altschul, Thomas L. Madden, Alejandro A.
Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J.
Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of
protein database search programs", Nucleic Acids Res. 25:3389-3402.
Reference for composition-based statistics: Alejandro A. Schaffer,
L. Aravind, Thomas L. Madden, Sergei Shavirin, John L. Spouge, Yuri
I. Wolf, Eugene V. Koonin, and Stephen F. Altschul (2001),
"Improving the accuracy of PSI-BLAST protein database searches with
composition-based statistics and other refinements", Nucleic Acids
Res. 29:2994-3005.
Database: 6dddf82adba8faa8981ea11cc38acf9d.SwissProt.fasta
15 sequences; 9,757 total letters
Query= ACIAD1566
Length=398
Score E
Sequences producing significant alignments: (Bits) Value
Q5ZHT1 Acyl-CoA dehydrogenase family member 11 [Gallus gallus] 181 2e-53
P96831 Probable acyl-CoA dehydrogenase FadE2 [Mycobacterium tuber... 168 3e-51
B3DMA2 Acyl-CoA dehydrogenase family member 11 [Rattus norvegicus] 174 5e-51
Q5R778 Acyl-CoA dehydrogenase family member 11 [Pongo abelii] 173 9e-51
Q709F0 Acyl-CoA dehydrogenase family member 11 [Homo sapiens] 169 3e-49
Q6JQN1 Acyl-CoA dehydrogenase family member 10 [Homo sapiens] 166 3e-48
Q80XL6 Acyl-CoA dehydrogenase family member 11 [Mus musculus] 166 3e-48
Q8K370 Acyl-CoA dehydrogenase family member 10 [Mus musculus] 153 1e-43
Q8RWZ3 Probable acyl-CoA dehydrogenase IBR3 [Arabidopsis thaliana] 152 2e-43
A5A6I0 Medium-chain specific acyl-CoA dehydrogenase, mitochondria... 147 4e-43
P11310 Medium-chain specific acyl-CoA dehydrogenase, mitochondria... 147 4e-43
Q9KJE8 (R)-benzylsuccinyl-CoA dehydrogenase [Thauera aromatica] 144 3e-42
P41367 Medium-chain specific acyl-CoA dehydrogenase, mitochondria... 142 2e-41
Q07417 Short-chain specific acyl-CoA dehydrogenase, mitochondrial... 141 5e-41
P45952 Medium-chain specific acyl-CoA dehydrogenase, mitochondria... 141 6e-41
>Q5ZHT1 Acyl-CoA dehydrogenase family member 11 [Gallus gallus]
Length=777
Score = 181 bits (458), Expect = 2e-53
Identities = 130/392 (33%), Positives = 202/392 (52%), Gaps = 28/392 (7%)
Query 11 DIAIKVEKFVREVVIPYERDPRR---DHHNCPTEE------LAVELREKAREAGVLAPHI 61
++ +KV++F+++ V P E++ H N TEE + L+E A+ G L
Sbjct 378 EVLLKVKQFMKQHVYPAEKEIAEYYAKHGN--TEERWKKPPVLERLKEMAKAEG-LWNLF 434
Query 62 LPDGTHLSQRGTAQVLIKTGLSPLGPLACQTAAPDEGNMYLLGQVGSDFIKQKFLKPLVE 121
LP + LSQ A + +TG P APD GNM +L G++ K+++L+PL+E
Sbjct 435 LPAVSSLSQLDYALIAEETGKRFFAPEVFNCQAPDTGNMEVLHLYGTEEQKKEWLEPLLE 494
Query 122 GNARSAFFMTEPAQENGAGSDPSMMQTRCWKEGDEWVIRGRKAFITGADG--AQVGIIMA 179
G S F MTEP + A SD + MQ ++G+ +VI G+K + +GA +V I+M
Sbjct 495 GKISSCFCMTEP---DVASSDATNMQCSIERDGNSYVINGKKWWSSGAGNPNCKVAIVMG 551
Query 180 KAEQGAC-------MFLVELPHPAIQIEQVPRTID--SSMPGGHATLWMNDLRVPAQQML 230
K + + M +V + P +++ + + GGH + ND+RVP M+
Sbjct 552 KTKNSSASRYKQHSMIIVPMDTPGVRLIRPLSVFGYIDEIHGGHFEVHFNDVRVPVSNMI 611
Query 231 GEPGEGFKYAQVRLSPARLSHCMRWYGACLRANEIATEYANQRMAFGQLLIDHEGCSFML 290
G GF+ AQ RL P R+ HCMR GA A EI + A QR FG+ L HE + +
Sbjct 612 LGEGRGFEIAQGRLGPGRIHHCMRSIGAAETALEILCQRAAQRETFGKKLYHHEVVAHWI 671
Query 291 AENLIDLKQVELMINWCASVLDQ--GELGTFESSMAKVSVSETLMRVADRCVQVMGGSGL 348
AE + ++Q L+ AS +D E +M KV V +++V D +QV GG+G+
Sbjct 672 AECRLSIEQARLLTLKTASKIDTLGNRKARKEVAMTKVVVPRAVLKVIDCAIQVCGGAGV 731
Query 349 TEQTIVEQVFREIRAFRIYDGPTEVHKWSIAK 380
++ + +F IR R+ DGP EVH +IA+
Sbjct 732 SQDFPLASMFAYIRTLRVADGPDEVHLSTIAR 763
>P96831 Probable acyl-CoA dehydrogenase FadE2 [Mycobacterium tuberculosis
(strain ATCC 25618 / H37Rv)]
Length=407
Score = 168 bits (426), Expect = 3e-51
Identities = 123/367 (34%), Positives = 184/367 (50%), Gaps = 21/367 (6%)
Query 27 YERDPRRDHHNCPTEELAVELREKAREAGVLAPHILPDGTHLSQRGTAQVLIKTGLS-PL 85
Y R H P + EL+ KA++ G L L + L+ A + TG S +
Sbjct 34 YRRAAGPADHTAPP--IIEELKTKAKDRG-LWNLFLSAESGLTNLEYAPLAEMTGWSMEI 90
Query 86 GPLACQTAAPDEGNMYLLGQVGSDFIKQKFLKPLVEGNARSAFFMTEPAQENGAGSDPSM 145
P A AAPD GNM +L G++ + ++L+PL++G RSAF MTEPA A SD
Sbjct 91 APEALNCAAPDTGNMEILHMFGTEQQRAQWLRPLLDGKIRSAFSMTEPAV---ASSDARN 147
Query 146 MQTRCWKEGDEWVIRGRKAFITGADGAQVGIIM--------AKAEQGACMFLVELPHPAI 197
++T ++G ++VI GRK + +GA + I++ A A Q M LV + P +
Sbjct 148 IETTISRDGADYVINGRKWWTSGAADPRCKILIVMGRTNPDAAAHQQQSMVLVPIDTPGV 207
Query 198 QIEQVPRTIDSSMPGGHATLWMNDLRVPAQQMLGEPGEGFKYAQVRLSPARLSHCMRWYG 257
I + GH + +++RVPA +LGE G GF AQ RL P R+ HCMR G
Sbjct 208 TIVRSTPVFGWQDRHGHCEIDYHNVRVPATNLLGEEGSGFAIAQARLGPGRIHHCMRALG 267
Query 258 ACLRANEIATEYANQRMAFGQLLIDHEGCSFMLAENLIDLKQVELMINWCASVLDQGELG 317
A RA + R+AFG+ L + +A++ ++ Q L+ A +DQ G
Sbjct 268 AAERALALMVNRVRNRVAFGRPLAEQGVVQQAIAQSRNEIDQARLLCEKAAWTIDQH--G 325
Query 318 TFES----SMAKVSVSETLMRVADRCVQVMGGSGLTEQTIVEQVFREIRAFRIYDGPTEV 373
E+ +M K V DR +QV G +G+++ T + +++ RA RI+DGP EV
Sbjct 326 NKEARHLVAMIKAVAPRVACDVIDRAIQVHGAAGVSDDTPLARLYGWHRAMRIFDGPDEV 385
Query 374 HKWSIAK 380
H SIA+
Sbjct 386 HLRSIAR 392
>B3DMA2 Acyl-CoA dehydrogenase family member 11 [Rattus norvegicus]
Length=779
Score = 174 bits (440), Expect = 5e-51
Identities = 120/401 (30%), Positives = 211/401 (53%), Gaps = 24/401 (6%)
Query 11 DIAIKVEKFVREVVIPYERDPRRDH-HNCPTEE-----LAVELREKAREAGVLAPHILPD 64
++ +V++F+++ V P E++ + N + E L +E ++ +A L LP
Sbjct 380 EVLTRVKQFMKQHVFPAEKEVAEYYAQNGNSAEKWEHPLVIEKLKEMAKAEGLWNLFLPA 439
Query 65 GTHLSQRGTAQVLIKTGLSPLGPLACQTAAPDEGNMYLLGQVGSDFIKQKFLKPLVEGNA 124
+ LSQ A + +TG P APD GNM +L GS+ KQ++L+PL+ G+
Sbjct 440 VSGLSQVDYALIAEETGKCFFAPDVFNCQAPDTGNMEVLHLYGSEQQKQQWLEPLLRGDI 499
Query 125 RSAFFMTEPAQENGAGSDPSMMQTRCWKEGDEWVIRGRKAFITGADG--AQVGIIMAKAE 182
S F MTEP N + SD + M+ ++G +++ G+K + +GA ++ +++ + E
Sbjct 500 TSVFCMTEP---NVSSSDATNMECSIQRDGGSYIVHGKKWWSSGAGNPKCKIAVVLGRTE 556
Query 183 QGAC-------MFLVELPHPAIQIEQVPRTIDSSMP---GGHATLWMNDLRVPAQQMLGE 232
+ M LV + P +++ + P ++ M GGH + N +RVPA ++
Sbjct 557 SPSVSRHKVHSMILVPMDTPGVELIR-PLSVFGYMDNVHGGHWEVHFNHVRVPASNLILG 615
Query 233 PGEGFKYAQVRLSPARLSHCMRWYGACLRANEIATEYANQRMAFGQLLIDHEGCSFMLAE 292
G GF+ +Q RL P R+ HCMR G R +I + A QR AFG+ L +HE + +A+
Sbjct 616 EGRGFEISQGRLGPGRIHHCMRSVGLAERILQIMCDRAVQREAFGKKLYEHEVVAHWIAK 675
Query 293 NLIDLKQVELMINWCASVLDQ--GELGTFESSMAKVSVSETLMRVADRCVQVMGGSGLTE 350
+ I ++++ L+ A +D E +M KV+ + + ++ADR +QV GG+G+++
Sbjct 676 SRIAIEEIRLLTLKAAHSIDTLGSAAARKEIAMIKVAAPKAVCKIADRAIQVHGGAGVSQ 735
Query 351 QTIVEQVFREIRAFRIYDGPTEVHKWSIAKKIKRDWLKRSK 391
+ ++ IR R+ DGP EVH +IAK +D ++ K
Sbjct 736 DYPLANMYAIIRTLRLADGPDEVHLSAIAKMELQDQARQLK 776
>Q5R778 Acyl-CoA dehydrogenase family member 11 [Pongo abelii]
Length=781
Score = 173 bits (438), Expect = 9e-51
Identities = 122/399 (31%), Positives = 207/399 (52%), Gaps = 24/399 (6%)
Query 11 DIAIKVEKFVREVVIPYERDPRRDHHNCPT------EELAVELREKAREAGVLAPHILPD 64
++ IKV+ F+++ ++P E++ + + L ++ ++ +A L LP
Sbjct 382 EVLIKVKHFMKQHILPAEKEVTEFYVQNENSVDKWGKPLVIDKLKEMAKAEGLWNLFLPA 441
Query 65 GTHLSQRGTAQVLIKTGLSPLGPLACQTAAPDEGNMYLLGQVGSDFIKQKFLKPLVEGNA 124
+ LSQ A + +TG P APD GNM +L GS+ K+++L+PL++GN
Sbjct 442 VSGLSQVDYALIAEETGKCFFAPDVFNCQAPDTGNMEILHLYGSEEQKKQWLEPLLQGNI 501
Query 125 RSAFFMTEPAQENGAGSDPSMMQTRCWKEGDEWVIRGRKAFITGADG--AQVGIIMAKAE 182
S F MTEP + A SD + ++ +E D +VI G+K + +GA ++ I++ + +
Sbjct 502 TSCFCMTEP---DVASSDATNIECSIQREEDSYVINGKKWWSSGAGNPKCKIAIVLGRTQ 558
Query 183 QGAC-------MFLVELPHPAIQIEQVPRTI---DSSMPGGHATLWMNDLRVPAQQMLGE 232
+ M LV + P ++I + P ++ + GGH + N +RVPA ++
Sbjct 559 NTSLSRHKQHSMILVPMNTPGVEIIR-PLSVFGYTDNFHGGHFEIHFNQVRVPATNLILG 617
Query 233 PGEGFKYAQVRLSPARLSHCMRWYGACLRANEIATEYANQRMAFGQLLIDHEGCSFMLAE 292
G GF+ +Q RL P R+ HCMR G RA +I E A QR+AF + L HE + +AE
Sbjct 618 EGRGFEISQGRLGPGRIHHCMRTVGLAERALQIMCERATQRIAFKKKLYAHEVVAHWIAE 677
Query 293 NLIDLKQVELMINWCASVLDQ-GELGT-FESSMAKVSVSETLMRVADRCVQVMGGSGLTE 350
+ I ++++ L+ A +D G G E +M KV+ + ++ D +QV GG+G+++
Sbjct 678 SRIAIEKIRLLTLKAAHSMDTLGSAGAKKEIAMIKVAAPRAVSKIVDWAIQVCGGAGVSQ 737
Query 351 QTIVEQVFREIRAFRIYDGPTEVHKWSIAKKIKRDWLKR 389
+ ++ R R+ DGP EVH +IA RD KR
Sbjct 738 DYPLANMYAITRVLRLADGPDEVHLSAIATMELRDQAKR 776
>Q709F0 Acyl-CoA dehydrogenase family member 11 [Homo sapiens]
Length=780
Score = 169 bits (427), Expect = 3e-49
Identities = 123/400 (31%), Positives = 208/400 (52%), Gaps = 26/400 (7%)
Query 11 DIAIKVEKFVREVVIPYERDPRRDHHNCPT------EELAVE-LREKAREAGVLAPHILP 63
++ IKV+ F+++ ++P E++ + + L ++ L+E A+ G L LP
Sbjct 381 EVLIKVKHFMKQHILPAEKEVTEFYVQNENSVDKWGKPLVIDKLKEMAKVEG-LWNLFLP 439
Query 64 DGTHLSQRGTAQVLIKTGLSPLGPLACQTAAPDEGNMYLLGQVGSDFIKQKFLKPLVEGN 123
+ LS A + +TG P APD GNM +L GS+ K+++L+PL++GN
Sbjct 440 AVSGLSHVDYALIAEETGKCFFAPDVFNCQAPDTGNMEVLHLYGSEEQKKQWLEPLLQGN 499
Query 124 ARSAFFMTEPAQENGAGSDPSMMQTRCWKEGDEWVIRGRKAFITGADG--AQVGIIMAKA 181
S F MTEP + A SD + ++ ++ D +VI G+K + +GA ++ I++ +
Sbjct 500 ITSCFCMTEP---DVASSDATNIECSIQRDEDSYVINGKKWWSSGAGNPKCKIAIVLGRT 556
Query 182 EQGAC-------MFLVELPHPAIQIEQVPRTI---DSSMPGGHATLWMNDLRVPAQQMLG 231
+ + M LV + P ++I + P ++ + GGH + N +RVPA ++
Sbjct 557 QNTSLSRHKQHSMILVPMNTPGVKIIR-PLSVFGYTDNFHGGHFEIHFNQVRVPATNLIL 615
Query 232 EPGEGFKYAQVRLSPARLSHCMRWYGACLRANEIATEYANQRMAFGQLLIDHEGCSFMLA 291
G GF+ +Q RL P R+ HCMR G RA +I E A QR+AF + L HE + +A
Sbjct 616 GEGRGFEISQGRLGPGRIHHCMRTVGLAERALQIMCERATQRIAFKKKLYAHEVVAHWIA 675
Query 292 ENLIDLKQVELMINWCASVLDQ-GELGT-FESSMAKVSVSETLMRVADRCVQVMGGSGLT 349
E+ I ++++ L+ A +D G G E +M KV+ + ++ D +QV GG+G++
Sbjct 676 ESRIAIEKIRLLTLKAAHSMDTLGSAGAKKEIAMIKVAAPRAVSKIVDWAIQVCGGAGVS 735
Query 350 EQTIVEQVFREIRAFRIYDGPTEVHKWSIAKKIKRDWLKR 389
+ + ++ R R+ DGP EVH +IA RD KR
Sbjct 736 QDYPLANMYAITRVLRLADGPDEVHLSAIATMELRDQAKR 775
>Q6JQN1 Acyl-CoA dehydrogenase family member 10 [Homo sapiens]
Length=1059
Score = 166 bits (421), Expect = 3e-48
Identities = 124/390 (32%), Positives = 190/390 (49%), Gaps = 30/390 (8%)
Query 15 KVEKFVREVVIPYERDPRRDHHNCPTEE-----LAVELREKAREAGV----LAPHILPD- 64
+++ F+ + V P E P H L +L+EKA+ G+ L P+
Sbjct 669 RLKHFMEQRVYPAE--PELQSHQASAARWSPSPLIEDLKEKAKAEGLWNLFLPLEADPEK 726
Query 65 --GTHLSQRGTAQVLIKTGLSPLGPLACQTAAPDEGNMYLLGQVGSDFIKQKFLKPLVEG 122
G L+ A + G S P C +APD GNM LL + G++ K ++L PL+EG
Sbjct 727 KYGAGLTNVEYAHLCELMGTSLYAPEVCNCSAPDTGNMELLVRYGTEAQKARWLIPLLEG 786
Query 123 NARSAFFMTEPAQENGAGSDPSMMQTRCWKEGDEWVIRGRKAFITGA--DGAQVGIIMAK 180
ARS F MTEP A SD + ++ +E +VI G K +ITG Q+ + M K
Sbjct 787 KARSCFAMTEPQV---ASSDATNIEASIREEDSFYVINGHKWWITGILDPRCQLCVFMGK 843
Query 181 AEQGA------CMFLVELPHPAIQIEQVPRTIDS--SMPGGHATLWMNDLRVPAQQMLGE 232
+ A + LV + P I+I + P T+ PGGH + +RVP + M+
Sbjct 844 TDPHAPRHRQQSVLLVPMDTPGIKIIR-PLTVYGLEDAPGGHGEVRFEHVRVPKENMVLG 902
Query 233 PGEGFKYAQVRLSPARLSHCMRWYGACLRANEIATEYANQRMAFGQLLIDHEGCSFMLAE 292
PG GF+ AQ RL P R+ HCMR G RA + R+AFG+ L++ +A+
Sbjct 903 PGRGFEIAQGRLGPGRIHHCMRLIGFSERALALMKARVKSRLAFGKPLVEQGTVLADIAQ 962
Query 293 NLIDLKQVELMINWCASVLD--QGELGTFESSMAKVSVSETLMRVADRCVQVMGGSGLTE 350
+ ++++Q L++ A ++D + + +M K+ RV DR +Q G +GL+
Sbjct 963 SRVEIEQARLLVLRAAHLMDLAGNKAAALDIAMIKMVAPSMASRVIDRAIQAFGAAGLSS 1022
Query 351 QTIVEQVFREIRAFRIYDGPTEVHKWSIAK 380
+ Q F RA R DGP EVH+ ++AK
Sbjct 1023 DYPLAQFFTWARALRFADGPDEVHRATVAK 1052
Score = 18.5 bits (36), Expect = 9.2
Identities = 14/42 (33%), Positives = 18/42 (43%), Gaps = 9/42 (21%)
Query 7 NLAHDIAIKVEKFVREVVIPYERDPRRDHHN--------CPT 40
NLA D A+K E F +P+ R +H CPT
Sbjct 591 NLAWDFAVK-EGFRVFKEMPFTNPLTRSYHTWARPQSQWCPT 631
>Q80XL6 Acyl-CoA dehydrogenase family member 11 [Mus musculus]
Length=779
Score = 166 bits (419), Expect = 3e-48
Identities = 116/400 (29%), Positives = 206/400 (52%), Gaps = 26/400 (7%)
Query 11 DIAIKVEKFVREVVIPYERDPRRDHHNCPTEE------LAVELREKAREAGVLAPHILPD 64
++ +V++F+++ V P E++ + L +E ++ +A L LP
Sbjct 380 EVLTRVKQFMKQHVFPAEKEVAEYYAQSGNSAEKWGHPLVIEKLKEMAKAEGLWNLFLPA 439
Query 65 GTHLSQRGTAQVLIKTGLSPLGPLACQTAAPDEGNMYLLGQVGSDFIKQKFLKPLVEGNA 124
+ LSQ A + +TG P APD GNM +L GS+ K+++L+PL+ G+
Sbjct 440 VSGLSQVDYALIAEETGKCFFAPDVFNCQAPDTGNMEVLHLYGSEQQKKQWLEPLLRGDI 499
Query 125 RSAFFMTEPAQENGAGSDPSMMQTRCWKEGDEWVIRGRKAFITGADG--AQVGIIMAKAE 182
S F MTEP N + SD + ++ ++G +++ G+K + +GA ++ I++ + E
Sbjct 500 TSVFCMTEP---NVSSSDATNIECTIQRDGGGYIVNGKKWWSSGAGNPKCKIAIVLGRTE 556
Query 183 QGAC-------MFLVELPHPAIQIEQVPRTID--SSMPGGHATLWMNDLRVPAQQMLGEP 233
+ M LV + P +++ + +M GGH + N +RVPA ++
Sbjct 557 SPSASRHRQHSMILVPMDTPGVELIRPLSVFGYMDNMHGGHWEVHFNHVRVPASNLILGE 616
Query 234 GEGFKYAQVRLSPARLSHCMRWYGACLRANEIATEYANQRMAFGQLLIDHEGCSFMLAEN 293
G GF+ +Q RL P R+ HCMR G R +I + A QR AF + L +HE + +A++
Sbjct 617 GRGFEISQGRLGPGRIHHCMRTVGLAERILQIMCDRAVQREAFKKKLYEHEVVAHWIAKS 676
Query 294 LIDLKQVELMINWCASVLDQGELGTF----ESSMAKVSVSETLMRVADRCVQVMGGSGLT 349
I ++++ L+ A +D LG+ E +M KV+ + + ++AD +QV GG+G++
Sbjct 677 RIAIEEIRLLTLKAAHSID--TLGSASARKEIAMIKVAAPKAVCKIADWAIQVHGGAGVS 734
Query 350 EQTIVEQVFREIRAFRIYDGPTEVHKWSIAKKIKRDWLKR 389
+ + ++ IR R+ DGP EVH +IAK +D +R
Sbjct 735 QDYPLANMYAIIRTLRLADGPDEVHLSAIAKMELQDQARR 774
>Q8K370 Acyl-CoA dehydrogenase family member 10 [Mus musculus]
Length=1069
Score = 153 bits (386), Expect = 1e-43
Identities = 117/386 (30%), Positives = 181/386 (47%), Gaps = 28/386 (7%)
Query 18 KFVREVVIPYERDPRRDHHNCPTEE-----LAVELREKAREAGV----LAPHILPD---G 65
+F+ + V P E P H + L +L+EKA+ G+ L P+ G
Sbjct 672 QFIEQKVYPLE--PELQRHQASADRWSPSPLIEDLKEKAKAEGLWNLFLPLETDPEKKYG 729
Query 66 THLSQRGTAQVLIKTGLSPLGPLACQTAAPDEGNMYLLGQVGSDFIKQKFLKPLVEGNAR 125
L+ A + G+S +APD GNM +L + G++ K ++L PL+EG R
Sbjct 730 AGLTNVEYAHLCEVMGMSLYASEIFNCSAPDTGNMEILVRYGTEEQKARWLVPLLEGRIR 789
Query 126 SAFFMTEPAQENGAGSDPSMMQTRCWKEGDEWVIRGRKAFITGA--DGAQVGIIMAKAE- 182
S F MTEP A SD S ++ +E +VI G K + +G ++ + M K +
Sbjct 790 SCFAMTEPQV---ASSDASNIEASIKEEDGCYVINGHKWWTSGILDPRCKLCVFMGKTDP 846
Query 183 -----QGACMFLVELPHPAIQIEQVPRTID-SSMPGGHATLWMNDLRVPAQQMLGEPGEG 236
Q M LV + P I + + PGGH + D+RVP + +L PG G
Sbjct 847 QAPRHQQQSMLLVPMDSPGITVIRPLSVFGLEDPPGGHGEVRFKDVRVPKENILLGPGRG 906
Query 237 FKYAQVRLSPARLSHCMRWYGACLRANEIATEYANQRMAFGQLLIDHEGCSFMLAENLID 296
F+ AQ RL P R+ HCMR G RA + R AFG+ L++ +A + ++
Sbjct 907 FEIAQGRLGPGRIHHCMRLIGYSERALALMKTRVMSRTAFGKPLVEQGTILADIARSRVE 966
Query 297 LKQVELMINWCASVLD--QGELGTFESSMAKVSVSETLMRVADRCVQVMGGSGLTEQTIV 354
++Q L++ A ++D + + +M K+ V V DR +Q G +GL+ +
Sbjct 967 IEQARLLVLKAAHLMDVAGNKTAALDIAMIKMVVPSMAYHVIDRAIQAFGAAGLSSDYPL 1026
Query 355 EQVFREIRAFRIYDGPTEVHKWSIAK 380
Q F RA R DGP EVH+ ++AK
Sbjct 1027 AQFFGWARALRFADGPDEVHQLTVAK 1052
>Q8RWZ3 Probable acyl-CoA dehydrogenase IBR3 [Arabidopsis thaliana]
Length=824
Score = 152 bits (384), Expect = 2e-43
Identities = 105/312 (34%), Positives = 160/312 (51%), Gaps = 16/312 (5%)
Query 81 GLSPLGPLACQTAAPDEGNMYLLGQVGSDFIKQKFLKPLVEGNARSAFFMTEPAQENGAG 140
G S P APD GNM ++ + G+ ++L PL+EG RS F MTEP A
Sbjct 508 GRSVWAPQVFNCGAPDTGNMEVILRYGNKEQISEWLIPLLEGRIRSGFAMTEPQV---AS 564
Query 141 SDPSMMQTRCWKEGDEWVIRGRKAFITGA--DGAQVGIIMAKAEQGA------CMFLVEL 192
SD + ++ ++GD +VI G K + +GA +V I+M K + A M LV++
Sbjct 565 SDATNIECSIRRQGDSYVINGTKWWTSGAMDPRCRVLILMGKTDFNAPKHKQQSMILVDM 624
Query 193 PHPAIQIEQVPRTIDS--SMPGGHATLWMNDLRVPAQQMLGEPGEGFKYAQVRLSPARLS 250
P I +++ P T+ P GHA + ++ VPA+ +L G GF+ AQ RL P RL
Sbjct 625 RTPGISVKR-PLTVFGFDDAPHGHAEISFENVVVPAKNILLGEGRGFEIAQGRLGPGRLH 683
Query 251 HCMRWYGACLRANEIATEYANQRMAFGQLLIDHEGCSFMLAENLIDLKQVELMINWCASV 310
HCMR GA R E+ + A R FG+ + H LA+ ++L+ L++ A
Sbjct 684 HCMRLIGAAERGMELMAQRALSRKTFGKFIAQHGSFVSDLAKLRVELEGTRLLVLEAADH 743
Query 311 LDQ--GELGTFESSMAKVSVSETLMRVADRCVQVMGGSGLTEQTIVEQVFREIRAFRIYD 368
LD+ + +MAKV+ ++V D +QV G +G++ T++ ++ R RI D
Sbjct 744 LDKFGNKKARGILAMAKVAAPNMALKVLDTAIQVHGAAGVSSDTVLAHLWATARTLRIAD 803
Query 369 GPTEVHKWSIAK 380
GP EVH +I K
Sbjct 804 GPDEVHLGTIGK 815
>A5A6I0 Medium-chain specific acyl-CoA dehydrogenase, mitochondrial
[Pan troglodytes]
Length=421
Score = 147 bits (370), Expect = 4e-43
Identities = 112/377 (30%), Positives = 186/377 (49%), Gaps = 29/377 (8%)
Query 18 KFVREVVIPYERDPRRDHHNCPTEELAVELREKAREAGVLAPHILPDGTHLSQRGTAQVL 77
KF RE +IP + + T E V L +A E G++ HI P+ GT
Sbjct 54 KFAREEIIPVAAEYDK------TGEYPVPLIRRAWELGLMNTHI-PENCGGLGLGTFDAC 106
Query 78 IKTGLSPLGPLACQTAAPDEGNMYLLGQV-----GSDFIKQKFLKPLVEGNARSAFFMTE 132
+ + G QTA EGN LGQ+ G+D K+K+L + E A+ +TE
Sbjct 107 LISEELAYGCTGVQTAI--EGNS--LGQMPIIIAGNDQQKKKYLGRMTEEPLMCAYCVTE 162
Query 133 PAQENGAGSDPSMMQTRCWKEGDEWVIRGRKAFITGADGAQVGIIMAK--------AEQG 184
P GAGSD + ++T+ K+GDE++I G+K +IT A ++A+ A +
Sbjct 163 P----GAGSDVAGIKTKAEKKGDEYIINGQKMWITNGGKANWYFLLARSDPDPKAPANKA 218
Query 185 ACMFLVELPHPAIQIEQVPRTIDSSMPGGHATLWMNDLRVPAQQMLGEPGEGFKYAQVRL 244
F+VE P IQI + + ++ D++VP + +L G GFK A
Sbjct 219 FTGFIVEADTPGIQIGRKELNMGQRCSDTRGIVF-EDVKVPRENVLIGDGAGFKVAMGAF 277
Query 245 SPARLSHCMRWYGACLRANEIATEYANQRMAFGQLLIDHEGCSFMLAENLIDLKQVELMI 304
R G RA + AT+YA +R FG+LL++H+ SFMLAE + ++ +
Sbjct 278 DKTRPVVAAGAVGLAQRALDEATKYALERKTFGKLLVEHQAISFMLAEMAMKVELARMSY 337
Query 305 NWCASVLDQGELGTFESSMAKVSVSETLMRVADRCVQVMGGSGLTEQTIVEQVFREIRAF 364
A +D G T+ +S+AK + ++A VQ++GG+G + VE++ R+ + +
Sbjct 338 QRAAWEVDSGRRNTYYASIAKAFAGDIANQLATDAVQILGGNGFNTEYPVEKLMRDAKIY 397
Query 365 RIYDGPTEVHKWSIAKK 381
+IY+G +++ + +A++
Sbjct 398 QIYEGTSQIQRLIVARE 414
>P11310 Medium-chain specific acyl-CoA dehydrogenase, mitochondrial
[Homo sapiens]
Length=421
Score = 147 bits (370), Expect = 4e-43
Identities = 112/377 (30%), Positives = 186/377 (49%), Gaps = 29/377 (8%)
Query 18 KFVREVVIPYERDPRRDHHNCPTEELAVELREKAREAGVLAPHILPDGTHLSQRGTAQVL 77
KF RE +IP + + T E V L +A E G++ HI P+ GT
Sbjct 54 KFAREEIIPVAAEYDK------TGEYPVPLIRRAWELGLMNTHI-PENCGGLGLGTFDAC 106
Query 78 IKTGLSPLGPLACQTAAPDEGNMYLLGQV-----GSDFIKQKFLKPLVEGNARSAFFMTE 132
+ + G QTA EGN LGQ+ G+D K+K+L + E A+ +TE
Sbjct 107 LISEELAYGCTGVQTAI--EGNS--LGQMPIIIAGNDQQKKKYLGRMTEEPLMCAYCVTE 162
Query 133 PAQENGAGSDPSMMQTRCWKEGDEWVIRGRKAFITGADGAQVGIIMAK--------AEQG 184
P GAGSD + ++T+ K+GDE++I G+K +IT A ++A+ A +
Sbjct 163 P----GAGSDVAGIKTKAEKKGDEYIINGQKMWITNGGKANWYFLLARSDPDPKAPANKA 218
Query 185 ACMFLVELPHPAIQIEQVPRTIDSSMPGGHATLWMNDLRVPAQQMLGEPGEGFKYAQVRL 244
F+VE P IQI + + ++ D++VP + +L G GFK A
Sbjct 219 FTGFIVEADTPGIQIGRKELNMGQRCSDTRGIVF-EDVKVPKENVLIGDGAGFKVAMGAF 277
Query 245 SPARLSHCMRWYGACLRANEIATEYANQRMAFGQLLIDHEGCSFMLAENLIDLKQVELMI 304
R G RA + AT+YA +R FG+LL++H+ SFMLAE + ++ +
Sbjct 278 DKTRPVVAAGAVGLAQRALDEATKYALERKTFGKLLVEHQAISFMLAEMAMKVELARMSY 337
Query 305 NWCASVLDQGELGTFESSMAKVSVSETLMRVADRCVQVMGGSGLTEQTIVEQVFREIRAF 364
A +D G T+ +S+AK + ++A VQ++GG+G + VE++ R+ + +
Sbjct 338 QRAAWEVDSGRRNTYYASIAKAFAGDIANQLATDAVQILGGNGFNTEYPVEKLMRDAKIY 397
Query 365 RIYDGPTEVHKWSIAKK 381
+IY+G +++ + +A++
Sbjct 398 QIYEGTSQIQRLIVARE 414
>Q9KJE8 (R)-benzylsuccinyl-CoA dehydrogenase [Thauera aromatica]
Length=406
Score = 144 bits (363), Expect = 3e-42
Identities = 96/303 (32%), Positives = 159/303 (52%), Gaps = 17/303 (6%)
Query 92 TAAPDEGNMYLLGQVGSDFIKQKFLKPLVEGNARSAFFMTEPAQENGAGSDPSMMQTRCW 151
T PD N+Y L + GS + K+++ G SA TEP GAGSD S + T
Sbjct 102 TLPPDAPNLYYLEECGSPAQRDKYVRRYCRGEIDSAMMATEP----GAGSDISGLTTTAV 157
Query 152 KEGDEWVIRGRKAFITGADGAQVGIIM-------AKAEQGACMFLVELPHPAIQI-EQVP 203
+E +WVI G K FI+ D ++ I A ++ F+++ P ++I ++P
Sbjct 158 RENGQWVINGSKIFISKCDKDELFFICIAVTDKEAPTKRRFTAFILDKDTPGLRIGAEIP 217
Query 204 RTIDSSMPGGHATLWMNDLRVPAQQMLGEPGEGFKYAQVRLSPARLSHCMRWYGACLRAN 263
+ +MP +++++++RV + +LGE G+ F Q R R+ G R
Sbjct 218 --VIGAMPTW--SVYLDNVRVGDEAVLGEVGDAFIPLQNRFGVRRIELAAHCTGMAERLI 273
Query 264 EIATEYANQRMAFGQLLIDHEGCSFMLAENLIDLKQVELMINWCASVLDQGELGT-FESS 322
++ + AN R FG L D + +A++ I+L+QV L + + A DQG E++
Sbjct 274 QMMIDQANLRKTFGVALADRQTVQNWIADSTIELEQVRLQLYFTAWKSDQGHKDLRLEAA 333
Query 323 MAKVSVSETLMRVADRCVQVMGGSGLTEQTIVEQVFREIRAFRIYDGPTEVHKWSIAKKI 382
K++ +E L RVADR +Q+ GG GL+ + +E V R +R +R+ +G +E+H+ SIAKK+
Sbjct 334 SLKIAATEMLTRVADRAIQLHGGLGLSREMGIEYVARMVRIWRVVEGASEIHRMSIAKKL 393
Query 383 KRD 385
D
Sbjct 394 LTD 396
>P41367 Medium-chain specific acyl-CoA dehydrogenase, mitochondrial
[Sus scrofa]
Length=421
Score = 142 bits (359), Expect = 2e-41
Identities = 114/377 (30%), Positives = 184/377 (49%), Gaps = 29/377 (8%)
Query 18 KFVREVVIPYERDPRRDHHNCPTEELAVELREKAREAGVLAPHILPDGTHLSQRGTAQVL 77
KF RE +IP + R T E V L ++A E G++ HI P+ G
Sbjct 54 KFAREEIIPVAAEYDR------TGEYPVPLLKRAWELGLMNTHI-PESFGGLGLGIIDSC 106
Query 78 IKTGLSPLGPLACQTAAPDEGNMYLLGQV----GSDFIKQK-FLKPLVEGNARSAFFMTE 132
+ T G QTA E N LGQV G ++ +QK +L + E A+ +TE
Sbjct 107 LITEELAYGCTGVQTAI--EANT--LGQVPLIIGGNYQQQKKYLGRMTEEPLMCAYCVTE 162
Query 133 PAQENGAGSDPSMMQTRCWKEGDEWVIRGRKAFITGADGAQVGIIMAK--------AEQG 184
P GAGSD + ++T+ K+GDE++I G+K +IT A ++A+ A +
Sbjct 163 P----GAGSDVAGIKTKAEKKGDEYIINGQKMWITNGGKANWYFLLARSDPDPKAPASKA 218
Query 185 ACMFLVELPHPAIQIEQVPRTIDSSMPGGHATLWMNDLRVPAQQMLGEPGEGFKYAQVRL 244
F+VE P +QI + + ++ D+RVP + +L G GFK A
Sbjct 219 FTGFIVEADTPGVQIGRKEINMGQRCSDTRGIVF-EDVRVPKENVLTGEGAGFKIAMGTF 277
Query 245 SPARLSHCMRWYGACLRANEIATEYANQRMAFGQLLIDHEGCSFMLAENLIDLKQVELMI 304
R G RA + AT+YA +R FG+LL +H+G SF+LA+ + ++ L
Sbjct 278 DKTRPPVAAGAVGLAQRALDEATKYALERKTFGKLLAEHQGISFLLADMAMKVELARLSY 337
Query 305 NWCASVLDQGELGTFESSMAKVSVSETLMRVADRCVQVMGGSGLTEQTIVEQVFREIRAF 364
A +D G T+ +S+AK ++ ++A VQV GG+G + VE++ R+ + +
Sbjct 338 QRAAWEIDSGRRNTYYASIAKAYAADIANQLATDAVQVFGGNGFNTEYPVEKLMRDAKIY 397
Query 365 RIYDGPTEVHKWSIAKK 381
+IY+G ++ + IA++
Sbjct 398 QIYEGTAQIQRIIIARE 414
>Q07417 Short-chain specific acyl-CoA dehydrogenase, mitochondrial
[Mus musculus]
Length=412
Score = 141 bits (355), Expect = 5e-41
Identities = 105/377 (28%), Positives = 171/377 (45%), Gaps = 23/377 (6%)
Query 19 FVREVVIPYERDPRRDHHNCPTEELAVELREKAREAGVLAPHILPDGTHLSQRGTAQVLI 78
F + ++P R+H PT ++ +K E G+LA + + LS G +
Sbjct 48 FAEKELVPIAAQLDREHL-FPTAQV-----KKMGELGLLAMDVPEE---LSGAGLDYLAY 98
Query 79 KTGLSPLGPLACQTAA-PDEGNMYLLGQV---GSDFIKQKFLKPLVEGNARSAFFMTEPA 134
L + T N LG + GS KQ+++ P G+ F ++EP
Sbjct 99 SIALEEISRACASTGVIMSVNNSLYLGPILKFGSAQQKQQWITPFTNGDKIGCFALSEP- 157
Query 135 QENGAGSDPSMMQTRCWKEGDEWVIRGRKAFITGADGAQVGIIMAKAEQ-----GACMFL 189
G GSD T +EGD WV+ G KA+IT + A ++ A ++ G FL
Sbjct 158 ---GNGSDAGAASTTAREEGDSWVLNGTKAWITNSWEASATVVFASTDRSRQNKGISAFL 214
Query 190 VELPHPAIQIEQVPRTIDSSMPGGHATLWMNDLRVPAQQMLGEPGEGFKYAQVRLSPARL 249
V +P P + + + + A L D R+P + +LGEPG GFK A L R+
Sbjct 215 VPMPTPGLTLGKKEDKL-GIRASSTANLIFEDCRIPKENLLGEPGMGFKIAMQTLDMGRI 273
Query 250 SHCMRWYGACLRANEIATEYANQRMAFGQLLIDHEGCSFMLAENLIDLKQVELMINWCAS 309
+ G + + A +YA R AFG L + F LA+ + L+ L+ A
Sbjct 274 GIASQALGIAQASLDCAVKYAENRNAFGAPLTKLQNIQFKLADMALALESARLLTWRAAM 333
Query 310 VLDQGELGTFESSMAKVSVSETLMRVADRCVQVMGGSGLTEQTIVEQVFREIRAFRIYDG 369
+ D + T ES+MAK++ SE ++ + +Q++GG G + E+ +R+ R IY+G
Sbjct 334 LKDNKKPFTKESAMAKLAASEAATAISHQAIQILGGMGYVTEMPAERYYRDARITEIYEG 393
Query 370 PTEVHKWSIAKKIKRDW 386
+E+ + IA + R +
Sbjct 394 TSEIQRLVIAGHLLRSY 410
>P45952 Medium-chain specific acyl-CoA dehydrogenase, mitochondrial
[Mus musculus]
Length=421
Score = 141 bits (355), Expect = 6e-41
Identities = 114/377 (30%), Positives = 180/377 (48%), Gaps = 29/377 (8%)
Query 18 KFVREVVIPYERDPRRDHHNCPTEELAVELREKAREAGVLAPHILPDGTHLSQRGTAQVL 77
KF RE +IP P D E L ++A E G++ HI P+ GT
Sbjct 54 KFAREEIIPVA--PEYDKSG----EYPFPLIKRAWELGLINAHI-PESCGGLGLGTFDAC 106
Query 78 IKTGLSPLGPLACQTAAPDEGNMYLLGQV-----GSDFIKQKFLKPLVEGNARSAFFMTE 132
+ T G QTA E N LGQ+ G+D K+K+L + E A+ +TE
Sbjct 107 LITEELAYGCTGVQTAI--EANS--LGQMPVILAGNDQQKKKYLGRMTEQPMMCAYCVTE 162
Query 133 PAQENGAGSDPSMMQTRCWKEGDEWVIRGRKAFITGADGAQVGIIMAK--------AEQG 184
P+ AGSD + ++T+ K+GDE+VI G+K +IT A ++A+ A +
Sbjct 163 PS----AGSDVAAIKTKAEKKGDEYVINGQKMWITNGGKANWYFLLARSNPDPKVPASKA 218
Query 185 ACMFLVELPHPAIQIEQVPRTIDSSMPGGHATLWMNDLRVPAQQMLGEPGEGFKYAQVRL 244
F+VE P I I + + + D+RVP + +L G GFK A
Sbjct 219 FTGFIVEADTPGIHIGKKELNMGQRCSDTRGIAF-EDVRVPKENVLIGEGAGFKIAMGAF 277
Query 245 SPARLSHCMRWYGACLRANEIATEYANQRMAFGQLLIDHEGCSFMLAENLIDLKQVELMI 304
R + G RA + AT+YA R FG+LL++H+G SF+LAE + ++ L
Sbjct 278 DRTRPTVAAGAVGLAQRALDEATKYALDRKTFGKLLVEHQGVSFLLAEMAMKVELARLSY 337
Query 305 NWCASVLDQGELGTFESSMAKVSVSETLMRVADRCVQVMGGSGLTEQTIVEQVFREIRAF 364
A +D G T+ +S+AK + ++A VQ+ GG G + VE++ R+ + +
Sbjct 338 QRAAWEVDSGRRNTYYASIAKAFAGDIANQLATDAVQIFGGYGFNTEYPVEKLMRDAKIY 397
Query 365 RIYDGPTEVHKWSIAKK 381
+IY+G ++ + IA++
Sbjct 398 QIYEGTAQIQRLIIARE 414
Lambda K H a alpha
0.321 0.136 0.414 0.792 4.96
Gapped
Lambda K H a alpha sigma
0.267 0.0410 0.140 1.90 42.6 43.6
Effective search space used: 3091890
Database: 6dddf82adba8faa8981ea11cc38acf9d.SwissProt.fasta
Posted date: May 9, 2024 8:08 PM
Number of letters in database: 9,757
Number of sequences in database: 15
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Neighboring words threshold: 11
Window for multiple hits: 40
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Data ...
